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Eltrombopag in chronic myelomonocytic leukemia with severe thrombocytopenia. A Groupe Francophone des Myélodysplasies (GFM) study Leukemia (IF 12.8) Pub Date : 2024-09-12 Florence Rabian, Sylvie Chevret, Bérengère Gruson, Sylvain Thépot, Anouk Walter-Petrich, Thorsten Braun, Norbert Vey, José Miguel Torregrosa-Diaz, Pierre Peterlin, Andrea Toma, Maud D’Aveni, Jacques Delaunay, Laurence Legros, Nathalie Droin, Fatiha Chermat, Daniel Lusina, Lionel Adès, Rosa Sapena, Eric Solary, Pierre Fenaux, Raphael Itzykson
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USP4 regulates ribosome biogenesis and protein synthesis for hematopoietic stem cell regeneration and leukemia progression Leukemia (IF 12.8) Pub Date : 2024-09-12 Bo Liu, Xianli Zhang, Yuanyuan Zhou, Haiping Liu, Zhenkun Wang, Yuting Fu, Qiongdan Gao, Xiang Cheng, Qingyuan Sun, Zhenyu Ju
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CXCR4 as a therapeutic target in acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-09-11 Jan Korbecki, Mateusz Bosiacki, Patrycja Kupnicka, Katarzyna Barczak, Dariusz Chlubek, Irena Baranowska-Bosiacka
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Determinants of survival after first relapse of acute lymphoblastic leukemia: a Children’s Oncology Group study Leukemia (IF 12.8) Pub Date : 2024-09-11 Susan R. Rheingold, Deepa Bhojwani, Lingyun Ji, Xinxin Xu, Meenakshi Devidas, John A. Kairalla, Mary Shago, Nyla A. Heerema, Andrew J. Carroll, Heather Breidenbach, Michael Borowitz, Brent L. Wood, Anne L. Angiolillo, Barbara L. Asselin, W. Paul Bowman, Patrick Brown, ZoAnn E. Dreyer, Kimberly P. Dunsmore, Joanne M. Hilden, Eric Larsen, Kelly Maloney, Yousif Matloub, Leonard A. Mattano, Stuart S. Winter
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The non-canonical BAF chromatin remodeling complex is a novel target of spliceosome dysregulation in SF3B1-mutated chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-09-11 Daniel Hägerstrand, Blaž Oder, Diego Cortese, Ying Qu, Amrei Binzer-Panchal, Cecilia Österholm, Teresa Del Peso Santos, Leily Rabbani, Hassan Foroughi Asl, Aron Skaftason, Viktor Ljungström, August Lundholm, Maria Koutroumani, Zahra Haider, Cecilia Jylhä, John Mollstedt, Larry Mansouri, Karla Plevova, Andreas Agathangelidis, Lydia Scarfò, Marine Armand, Alice F. Muggen, Neil E. Kay, Tait Shanafelt
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Diverse mechanisms of leukemogenesis associated with PAX5 germline mutation Leukemia (IF 12.8) Pub Date : 2024-09-10 Laura Rachele Bettini, Grazia Fazio, Claudia Saitta, Rocco Piazza, Sonia Palamini, Chiara Buracchi, Stefano Rebellato, Nicola Santoro, Cristiano Simone, Andrea Biondi, Giovanni Cazzaniga
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Are measurable residual disease results after consolidation therapy useful in children with acute lymphoblastic leukemia? Leukemia (IF 12.8) Pub Date : 2024-09-10 Janine Stutterheim, Rachella van der Waarden, Hester A. de Groot-Kruseman, Edwin Sonneveld, Valérie de Haas, Rana Dandis, C. Ellen van der Schoot, Vincent H. J. van der Velden, Rob Pieters
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Early-life tobacco exposure is causally implicated in aberrant RAG-mediated recombination in childhood acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-09-09 Tanxin Liu, Keren Xu, Anmol Pardeshi, Swe Swe Myint, Alice Y. Kang, Libby M. Morimoto, Michael R. Lieber, Joseph L. Wiemels, Scott C. Kogan, Catherine Metayer, Adam J. de Smith
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Cohesin mutations in acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-09-09 Austin Boucher, Josiah Murray, Sridhar Rao
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JAK2V617F impairs lymphoid differentiation in myeloproliferative neoplasms Leukemia (IF 12.8) Pub Date : 2024-09-07 Daniel C. Choi, Nassima Messali, Narasimha Rao Uda, Ghaith Abu-Zeinah, Pouneh Kermani, Maria Mia Yabut, Heidi E. L. Lischer, Franco Castillo Tokumori, Katie Erdos, Thomas Lehmann, Marta Sobas, Tata Nageswara Rao, Joseph M. Scandura
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Plasma cell disorders supress mucosal anti-bacterial immunity: another dimension of immunoparesis in plasma cell neoplasms Leukemia (IF 12.8) Pub Date : 2024-09-07 Sian Faustini, Y. L. Tracey Chan, Lilli Evans, Emily Collman, Alec Rapson, Claire Backhouse, Annabelle Emery, John P. Campbell, Sally Moore, Alex Richter, Guy Pratt, Mark T. Drayson, Jennifer L. J. Heaney
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Phase 3 study of gilteritinib versus salvage chemotherapy in predominantly Asian patients with relapsed/refractory FLT3-mutated acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-09-05 Jianxiang Wang, Bin Jiang, Jian Li, Ligen Liu, Xin Du, Hao Jiang, Jianda Hu, Menghe Yuan, Taishi Sakatani, Takeshi Kadokura, Masato Takeuchi, Masanori Kosako, Xiao Ma, Larisa Girshova, Jerome Tan, Sergey Bondarenko, Lily Wong Lee Lee, Archrob Khuhapinant, Elena Martynova, Nahla Hasabou
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Mutational mechanisms in multiply relapsed pediatric acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-09-04 Cédric G. van der Ham, Lianne C. Suurenbroek, Michelle M. Kleisman, Željko Antić, Stefan H. Lelieveld, Marley Yeong, Liset Westera, Edwin Sonneveld, Peter M. Hoogerbrugge, Vincent H. J. van der Velden, Frank N. van Leeuwen, Roland P. Kuiper
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Genome-wide CRISPR/Cas9 library screening identified OGDH as a regulator of disease progress and resistance to decitabine in myelodysplastic neoplasm by reprogramming glutamine metabolism Leukemia (IF 12.8) Pub Date : 2024-09-03 Xiaoyan Xu, Jiaqian Qi, Hong Wang, Ziyan Zhang, Tingting Pan, Xueqian Li, Jingyi Yang, Haohao Han, Mengting Guo, Meng Zhou, Chengsen Cai, Yaqiong Tang, Qixiu Hou, Suning Chen, Depei Wu, Yue Han
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Mosaic chromosomal alterations in hematopoietic cells and clinical outcomes in patients with multiple myeloma Leukemia (IF 12.8) Pub Date : 2024-09-02 Simon Husby, Morten Tulstrup, Mads Harsløf, Christian Nielsen, Eva Haastrup, Lene Hyldahl Ebbesen, Mette Klarskov Andersen, Maroulio Pertesi, Christian Brieghel, Carsten U. Niemann, Björn Nilsson, Agoston Gyula Szabo, Niels Frost Andersen, Niels Abildgaard, Annette Vangsted, Kirsten Grønbæk
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Star wars against leukemia: attacking the clones Leukemia (IF 12.8) Pub Date : 2024-09-02 Monika M. Toma, Tomasz Skorski
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Impact of somatic gene mutations on the risk of thrombosis in myelofibrosis Leukemia (IF 12.8) Pub Date : 2024-08-30 Irene Pastor-Galán, Arturo Pereira, Eduardo Arellano-Rodrigo, Iván Martín, Adrián Mosquera-Orgueira, María-Teresa Gómez-Casares, Alberto Hernández-Sánchez, Francisca Ferrer-Marín, Elvira Mora, Patricia Velez, Rosa Ayala, Anna Angona, Natalia de las Heras, Elena Magro, María-Isabel Mata-Vázquez, María-Laura Fox, Sonia González de Villambrosía, María-José Ramírez, Ana García, Valentín García-Gutiérrez
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IL-10R inhibition reprograms tumor-associated macrophages and reverses drug resistance in multiple myeloma Leukemia (IF 12.8) Pub Date : 2024-08-30 Jennifer Sun, Stefan Corradini, Feda Azab, Monica Shokeen, Barbara Muz, Katerina E. Miari, Mina Maksimos, Camila Diedrich, Obed Asare, Kinan Alhallak, Chaelee Park, Berit Lubben, Yixuan Chen, Ola Adebayo, Hannah Bash, Sarah Kelley, Mark Fiala, Diane E. Bender, Haibin Zhou, Shaomeng Wang, Ravi Vij, Mark T. S. Williams, Abdel Kareem Azab
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The clinical impact of acquired von Willebrand syndrome secondary to Waldenström macroglobulinemia: an underrecognized source of major bleeding events Leukemia (IF 12.8) Pub Date : 2024-08-28 Karan L. Chohan, Rajiv K. Pruthi, Saurabh Zanwar, Jonas Paludo, Ronald Go, Animesh Pardanani, Aneel Ashrani, Joselle M. Cook, Carrie A. Thompson, Asher Chanan-Khan, Sikander Ailawadhi, Thomas M. Habermann, Thomas E. Witzig, Morie A. Gertz, David Dingli, Fransis K. Buadi, Angela Dispenzieri, Nelson Leung, Shaji K. Kumar, Vincent Rajkumar, William L. Nichols, Robert A. Kyle, Stephen M. Ansell, Prashant
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Genetic hallmarks and clinical implications of chromothripsis in childhood T-cell acute lymphoblastic leukemia Leukemia (IF 12.8) Pub Date : 2024-08-27 Agata Pastorczak, Zuzanna Urbanska, Borys Styka, Karolina Miarka-Walczyk, Lukasz Sedek, Kamila Wypyszczak, Anna Wakulinska, Zuzanna Nowicka, Tomasz Szczepański, Marcin Stańczak, Wojciech Fendler, Jerzy Kowalczyk, Wojciech Młynarski, Monika Lejman
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Third-generation anti-CD19 CAR T cells for relapsed/refractory chronic lymphocytic leukemia: a phase 1/2 study Leukemia (IF 12.8) Pub Date : 2024-08-27 Patrick Derigs, Maria-Luisa Schubert, Peter Dreger, Anita Schmitt, Schayan Yousefian, Simon Haas, Caroline Röthemeier, Brigitte Neuber, Angela Hückelhoven-Krauss, Monika Brüggemann, Helga Bernhard, Guido Kobbe, Albrecht Lindemann, Mathias Rummel, Birgit Michels, Felix Korell, Anthony D. Ho, Carsten Müller-Tidow, Michael Schmitt
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Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation Leukemia (IF 12.8) Pub Date : 2024-08-26 Vilma Dembitz, Hannah Lawson, Richard Burt, Sirisha Natani, Céline Philippe, Sophie C. James, Samantha Atkinson, Jozef Durko, Lydia M. Wang, Joana Campos, Aoife M. S. Magee, Keith Woodley, Michael J. Austin, Ana Rio-Machin, Pedro Casado, Findlay Bewicke-Copley, Giovanny Rodriguez Blanco, Diego Pereira-Martins, Lieve Oudejans, Emeline Boet, Alex von Kriegsheim, Juerg Schwaller, Andrew J. Finch, Bela
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A multidimensional analysis reveals distinct immune phenotypes and the composition of immune aggregates in pediatric acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-08-26 Joost B. Koedijk, Inge van der Werf, Livius Penter, Marijn A. Vermeulen, Farnaz Barneh, Alicia Perzolli, Joyce I. Meesters-Ensing, Dennis S. Metselaar, Thanasis Margaritis, Marta Fiocco, Hester A. de Groot-Kruseman, Rubina Moeniralam, Kristina Bang Christensen, Billie Porter, Kathleen Pfaff, Jacqueline S. Garcia, Scott J. Rodig, Catherine J. Wu, Henrik Hasle, Stefan Nierkens, Mirjam E. Belderbos, C
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Downregulation of UBA1 expression in myelodysplastic neoplasm Leukemia (IF 12.8) Pub Date : 2024-08-23 Yue Wei, Hong Zheng, Ziyi Li, Pamela Pennington Lockyer, Faezeh Darbaniyan, Rashmi Kanagal-Shamanna, Hui Yang, Danielle Hammond, Guillermo Garcia-Manero
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Menin inhibitors in pediatric acute leukemia: a comprehensive review and recommendations to accelerate progress in collaboration with adult leukemia and the international community Leukemia (IF 12.8) Pub Date : 2024-08-23 Branko Cuglievan, Hagop Kantarjian, Jeffrey E. Rubnitz, Todd M. Cooper, C. Michel Zwaan, Jessica A. Pollard, Courtney D. DiNardo, Tapan M. Kadia, Erin Guest, Nicholas J. Short, David McCall, Naval Daver, Cesar Nunez, Fadi G. Haddad, Miriam Garcia, Kapil N. Bhalla, Abhishek Maiti, Samanta Catueno, Warren Fiskus, Bing Z. Carter, Amber Gibson, Michael Roth, Sajad Khazal, Priti Tewari, Hussein A. Abbas
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Chromosome 9p trisomy increases stem cells clonogenic potential and fosters T-cell exhaustion in JAK2-mutant myeloproliferative neoplasms Leukemia (IF 12.8) Pub Date : 2024-08-23 Chiara Carretta, Sandra Parenti, Matteo Bertesi, Sebastiano Rontauroli, Filippo Badii, Lara Tavernari, Elena Genovese, Marica Malerba, Elisa Papa, Samantha Sperduti, Elena Enzo, Margherita Mirabile, Francesca Pedrazzi, Anita Neroni, Camilla Tombari, Barbara Mora, Margherita Maffioli, Marco Mondini, Marco Brociner, Monica Maccaferri, Elena Tenedini, Silvia Martinelli, Niccolò Bartalucci, Elisa Bianchi
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STING is crucial for the survival of RUNX1::RUNX1T1 leukemia cells Leukemia (IF 12.8) Pub Date : 2024-08-23 Yue Sun, Yushuang Wu, Guozheng Pang, Jingru Huang, Mengyao Sheng, Jiaying Xie, Pingyue Chen, Yin Wang, Dongrui Yin, Guangjie Zhao, Stefan K. Bohlander, Jian Huang, Guo-Liang Xu, Hai Gao, Dan Zhou, Yuheng Shi
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Evolution of T-cell fitness through AML progression: enhanced bispecific T-cell engager-mediated function of bone marrow T cells at remission compared to initial diagnosis and relapse Leukemia (IF 12.8) Pub Date : 2024-08-22 Maryam Kazerani, Anetta Marcinek, Nora Philipp, Bettina Brauchle, Jonathan Jonas Taylor, Helena Domínguez Moreno, Andrea Terrasi, Benjamin Tast, Lisa Rohrbacher, Yingshuai Wang, Maximilian Warm, Alica-Joana Emhardt, Giulia Magno, Karsten Spiekermann, Tobias Herold, Tobias Straub, Sebastian Theurich, Gunnar Schotta, Roman Kischel, Veit L. Bücklein, Marion Subklewe
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Optimal prognostic threshold for measurable residual disease positivity by multiparameter flow cytometry in acute myeloid leukemia (AML) Leukemia (IF 12.8) Pub Date : 2024-08-21 Eduardo Rodríguez-Arbolí, Megan Othus, Sylvie D. Freeman, Francesco Buccisano, Lok Lam Ngai, Ian Thomas, Raffaele Palmieri, Jacqueline Cloos, Sean Johnson, Elisa Meddi, Nigel H. Russell, Adriano Venditti, Patrycja Gradowska, Gert J. Ossenkoppele, Bob Löwenberg, Roland B. Walter
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Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties Leukemia (IF 12.8) Pub Date : 2024-08-21 Héléna Boutzen, Alex Murison, Alexa Oriecuia, Suraj Bansal, Christopher Arlidge, Jean C. Y. Wang, Mathieu Lupien, Kerstin B. Kaufmann, John E. Dick
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Prevalence of metabolic comorbidities and viral co-infections in monoclonal gammopathy: a retrospective analysis Leukemia (IF 12.8) Pub Date : 2024-08-20 Tinatin Muradashvili, Mansen Yu, Sabrina L. Browning, Noffar Bar, Elan Gorshein, Terri L. Parker, Natalia Neparidze
Monoclonal gammopathy (MG) represents a spectrum of related diseases, with monoclonal gammopathy of undetermined significance (MGUS) being the most prevalent. MGUS invariably precedes every case of smoldering multiple myeloma (SMM) and clinical multiple myeloma (MM). A risk of progression from MGUS to MM is about 1% per year [1], whereas for patients with SMM, it can reach up to 63% in 2 years [2]
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Efficacy and safety of bosutinib in previously treated patients with chronic myeloid leukemia: final results from the BYOND trial Leukemia (IF 12.8) Pub Date : 2024-08-20 Carlo Gambacorti-Passerini, Tim H. Brümmendorf, Elisabetta Abruzzese, Kevin R. Kelly, Vivian G. Oehler, Valentín García-Gutiérrez, Henrik Hjorth-Hansen, Thomas Ernst, Eric Leip, Simon Purcell, Gerald Luscan, Andrea Viqueira, Francis J. Giles, Andreas Hochhaus
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Atrial fibrillation burden and clinical outcomes following BTK inhibitor initiation Leukemia (IF 12.8) Pub Date : 2024-08-17 John Alan Gambril, Sanam M. Ghazi, Stephen Sansoterra, Mussammat Ferdousi, Onaopepo Kola-Kehinde, Patrick Ruz, Adam S. Kittai, Kerry Rogers, Michael Grever, Seema Bhat, Tracy Wiczer, John C. Byrd, Jennifer Woyach, Daniel Addison
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Identification, risk factors, and clinical course of CNS relapse in DLBCL patients across 19 prospective phase 2 and 3 trials—a LYSA and GLA/ DSHNHL collaboration Leukemia (IF 12.8) Pub Date : 2024-08-16 Fabian Frontzek, Loïc Renaud, Ulrich Dührsen, Viola Poeschel, Sophie Bernard, Loïc Chartier, Nicolas Ketterer, Christian Récher, Olivier Fitoussi, Gerhard Held, Olivier Casasnovas, Corinne Haioun, Nicolas Mounier, Hervé Tilly, Franck Morschhauser, Steven Le Gouill, Imke E. Karsten, Gerben Duns, Christian Steidl, David W. Scott, Wolfram Klapper, Andreas Rosenwald, German Ott, Thierry Molina, Georg Lenz
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Autophagy in cancer resistance: New combinatorial strategy for cancer therapy Leukemia (IF 12.8) Pub Date : 2024-08-15 Eloïne Bestion, Régis Costello, Soraya Mezouar, Philippe Halfon
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The VLA-4 integrin is constitutively active in circulating chronic lymphocytic leukemia cells via BCR autonomous signaling: a novel anchor-independent mechanism exploiting soluble blood-borne ligands Leukemia (IF 12.8) Pub Date : 2024-08-14 Erika Tissino, Annalisa Gaglio, Antonella Nicolò, Federico Pozzo, Tamara Bittolo, Francesca Maria Rossi, Riccardo Bomben, Paola Nanni, Ilaria Cattarossi, Eva Zaina, Anna Maria Zimbo, Giulia Ianna, Guido Capasso, Gabriela Forestieri, Riccardo Moia, Moumita Datta, Andrea Härzschel, Jacopo Olivieri, Giovanni D’Arena, Luca Laurenti, Francesco Zaja, Annalisa Chiarenza, Giuseppe A. Palumbo, Enrica Antonia
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Loss of Dnajc21 leads to cytopenia and altered nucleotide metabolism in zebrafish Leukemia (IF 12.8) Pub Date : 2024-08-13 Sarada Ketharnathan, Sujata Pokharel, Sergey V. Prykhozhij, Anna Cordeiro-Santanach, Kevin Ban, Serkan Dogan, Huy-Dung Hoang, Mira F. Liebman, Elaine Leung, Tommy Alain, Irina Alecu, Steffany A. L. Bennett, Miroslava Čuperlović-Culf, Yigal Dror, Jason N. Berman
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GNAS knockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma Leukemia (IF 12.8) Pub Date : 2024-08-08 Michael Y. He, Kit I. Tong, Ting Liu, Ryder Whittaker Hawkins, Victoria Shelton, Yong Zeng, Mehran Bakhtiari, Yufeng Xiao, Guangrong Zheng, Ali Sakhdari, Lin Yang, Wenxi Xu, David G. Brooks, Rob C. Laister, Housheng Hansen He, Robert Kridel
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Transfusion independence after lenalidomide discontinuation in patients with del(5q) myelodysplastic neoplasm: a HARMONY Alliance study Leukemia (IF 12.8) Pub Date : 2024-08-05 Elena Crisà, Elvira Mora, Ulrich Germing, Cecile Bally, Maria Diez Campelo, Mikko Myllymäki, Martin Jädersten, Rami Komrokji, Uwe Platzbecker, Detlef Haase, Wolf-Karsten Hofmann, Najla H. Al Ali, Daniela Barraco, Juan José Bargay, Teresa Bernal, Felix López Cadenas, Anna Calvisi, Isabella Capodanno, Marco Cerrano, Rosanna Ciancia, Monica Crugnola, Andrea Kündgen, Carlo Finelli, Claudio Fozza, Chiara
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BCR::ABL1 Proteolysis-targeting chimeras (PROTACs): The new frontier in the treatment of Ph+ leukemias? Leukemia (IF 12.8) Pub Date : 2024-08-04 Nataly Cruz-Rodriguez, Hua Tang, Benjamin Bateman, Weiping Tang, Michael Deininger
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Rational combinatorial targeting by adapter CAR-T-cells (AdCAR-T) prevents antigen escape in acute myeloid leukemia Leukemia (IF 12.8) Pub Date : 2024-08-03 Daniel Atar, Lara Ruoff, Anna-Sophia Mast, Simon Krost, Moustafa Moustafa-Oglou, Sophia Scheuermann, Beate Kristmann, Maximilian Feige, Aysegül Canak, Kathrin Wolsing, Lennart Schlager, Karin Schilbach, Latifa Zekri, Martin Ebinger, Daniel Nixdorf, Marion Subklewe, Johannes Schulte, Claudia Lengerke, Irmela Jeremias, Niels Werchau, Joerg Mittelstaet, Peter Lang, Rupert Handgretinger, Patrick Schlegel
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Clinical implications of residual normal plasma cells within bone marrow across various disease stages in multiple myeloma Leukemia (IF 12.8) Pub Date : 2024-08-02 Wenqiang Yan, Lihui Shi, Jingyu Xu, Lingna Li, Jian Cui, Yuntong Liu, Jieqiong Zhou, Chenxing Du, Tengteng Yu, Shuaishuai Zhang, Rui Lv, Weiwei Sui, Shuhui Deng, Xiaoqing Li, Xin Du, Yan Xu, Dehui Zou, Lugui Qiu, Mu Hao, Gang An
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Absence of ABL1 exon 2-encoded SH3 residues in BCR::ABL1 destabilizes the autoinhibited kinase conformation and confers resistance to asciminib Leukemia (IF 12.8) Pub Date : 2024-07-31 Ariel Leyte-Vidal, RosaAnna DeFilippis, Ian R. Outhwaite, Isabelle Kwan, Ji Young Lee, Carlyn Leavitt, Kaeli B. Miller, Delphine Rea, Aziz M. Rangwala, Kevin Lou, Suhana Patel, Ailin Alvarez, Kevan M. Shokat, Ivet Bahar, Markus A. Seeliger, Neil P. Shah
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Tumor evolution analysis uncovered immune-escape related mutations in relapse of diffuse large B-cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-07-30 Xueshuai Han, Jingru Sui, Kui Nie, Yang Zhao, Xuan Lv, Jindou Xie, Leonard Tan, Rex K. H. Au-Yeung, Jiao Ma, Giorgio Inghirami, Olivier Elemento, Wayne Tam, Zhaoqi Liu
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REXO5 promotes genomic integrity through regulating R-loop using its exonuclease activity Leukemia (IF 12.8) Pub Date : 2024-07-30 Ye Jin Lee, Seo Yun Lee, Soomi Kim, Soo-Hyun Kim, Soo Hyeon Lee, Sungho Park, Jae Jin Kim, Dong-Wook Kim, Hongtae Kim
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The m6A methyltransferase METTL14 promotes cell proliferation via SETBP1-mediated activation of PI3K-AKT signaling pathway in myelodysplastic neoplasms Leukemia (IF 12.8) Pub Date : 2024-07-25 Lingxu Jiang, Yudi Zhang, Jiejing Qian, Xinping Zhou, Liya Ma, Shuanghong Zhu, Lu Wang, Wei Wang, Wenli Yang, Yingwan Luo, Wei Lang, Gaixiang Xu, Yanling Ren, Chen Mei, Li Ye, Qi Zhang, Xiaozhen Liu, Jie Jin, Jie Sun, Hongyan Tong
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Older MRD vs. younger MUD in patients older than 50 years with AML in remission using post-transplant cyclophosphamide Leukemia (IF 12.8) Pub Date : 2024-07-24 Simona Piemontese, Myriam Labopin, Goda Choi, Annoek E. C. Broers, Jacopo Peccatori, Ellen Meijer, Gwendolyn Van Gorkom, Montserrat Rovira, Maria Jesús Pascual Cascon, Simona Sica, Jan Vydra, Alexander Kulagin, Alexandros Spyridonidis, Arnon Nagler, Ali Bazarbachi, Bipin Savani, Eolia Brissot, Jaime Sanz, Mohamad Mohty, Fabio Ciceri
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Mutation in Bruton Tyrosine Kinase (BTK) A428D confers resistance To BTK-degrader therapy in chronic lymphocytic leukemia Leukemia (IF 12.8) Pub Date : 2024-07-24 Richard L. Wong, Michael Y. Choi, Huan-You Wang, Thomas J. Kipps
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In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis Leukemia (IF 12.8) Pub Date : 2024-07-23 Ngoc Tung Tran, Robin Graf, Ernesto Acevedo-Ochoa, Janine Trombke, Timm Weber, Thomas Sommermann, Claudia Salomon, Ralf Kühn, Klaus Rajewsky, Van Trung Chu
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Improved outcome of COVID-19 over time in patients treated with CAR T-cell therapy: Update of the European COVID-19 multicenter study on behalf of the European Society for Blood and Marrow Transplantation (EBMT) Infectious Diseases Working Party (IDWP) and the European Hematology Association (EHA) Lymphoma Group Leukemia (IF 12.8) Pub Date : 2024-07-23 Anne Mea Spanjaart, Per Ljungman, Gloria Tridello, Juana Schwartz, Nuria Martinez-Cibrián, Pere Barba, Mi Kwon, Lucia Lopez-Corral, Joaquin Martinez-Lopez, Christelle Ferra, Roberta Di Blasi, Hervé Ghesquieres, Pim Mutsaers, Friso Calkoen, Margot Jak, Jaap van Doesum, Joost S. P. Vermaat, Marjolein van der Poel, Johan Maertens, Massimiliano Gambella, Elisabetta Metafuni, Fabio Ciceri, Riccardo Saccardi
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Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes Leukemia (IF 12.8) Pub Date : 2024-07-20 Johann-Christoph Jann, Christopher B. Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin M. Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S. Winer, Martha Wadleigh, Richard M. Stone, Daniel J. DeAngelo, Jacqueline S. Garcia, Torsten Haferlach, R. Coleman Lindsley, Marlise R. Luskin, Maximilian Stahl, Zuzana Tothova
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Silencing GNAS enhances HDAC3i efficacy in CREBBP wild type B cell lymphoma Leukemia (IF 12.8) Pub Date : 2024-07-19 Patrizia Mondello
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Nudt15-mediated inflammatory signaling contributes to divergent outcomes in leukemogenesis and hematopoiesis Leukemia (IF 12.8) Pub Date : 2024-07-18 Jiachen Wang, Yu Zhang, Lei Li, Liujiao Wang, Shuainan Sun, Bowu Wang, Yanwen Ge, Zhonghui Zhang
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Clinical and molecular characteristics of extramedullary acute myeloid leukemias Leukemia (IF 12.8) Pub Date : 2024-07-18 Tariq Kewan, Waled S. Bahaj, Carmelo Gurnari, Olisaemeka D. Ogbue, Sudipto Mukherjee, Anjali Advani, James R. Cook, Heesun J. Rogers, Hetty E. Carraway, Suresh K. Balasubramanian, Valeria Visconte, Jaroslaw P. Maciejewski
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Proteomic screening identifies PF4/Cxcl4 as a critical driver of myelofibrosis Leukemia (IF 12.8) Pub Date : 2024-07-18 Daniele Capitanio, Francesca R. Calledda, Vittorio Abbonante, Daniele Cattaneo, Manuela Moriggi, Bartalucci Niccolò, Cristina Bucelli, Delfina Tosi, Umberto Gianelli, Alessandro Maria Vannucchi, Alessandra Iurlo, Cecilia Gelfi, Alessandra Balduini, Alessandro Malara
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Immunofluorescence microscopy on the blood smear identifies patients with myeloproliferative neoplasms Leukemia (IF 12.8) Pub Date : 2024-07-17 Carlo Zaninetti, Leonard Vater, Lars Kaderali, Carl C. Crodel, Tina M. Schnöder, Jessica Fuhrmann, Leonard Swensson, Jan Wesche, Carmen Freyer, Andreas Greinacher, Florian H. Heidel
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Molecular relapse after first-line intensive therapy in patients with CBF or NPM1-mutated acute myeloid leukemia – a FILO study Leukemia (IF 12.8) Pub Date : 2024-07-17 Corentin Orvain, Sarah Bertoli, Pierre Peterlin, Yohann Desbrosses, Pierre-Yves Dumas, Alexandre Iat, Marie-Anne Hospital, Martin Carre, Emmanuelle Tavernier, Jérémie Riou, Anne Bouvier, Audrey Bidet, Sylvie Tondeur, Florian Renosi, Marie-Joelle Mozziconacci, Pascale Flandrin-Gresta, Bérengère Dadone-Montaudié, Eric Delabesse, Arnaud Pigneux, Mathilde Hunault-Berger, Christian Recher
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Validation of independent prognostic significance of blast count in a large cohort of MDS patients Leukemia (IF 12.8) Pub Date : 2024-07-16 Raniah Al Amri, Vandana Baloda, Sara A. Monaghan, Flavia G. Rosado, Erika M. Moore, Bryan Rea, Miroslav Djokic, Nidhi Aggarwal, Svetlana A. Yatsenko, Nathanael G. Bailey
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FBXL6 is a vulnerability in AML and unmasks proteolytic cleavage as a major experimental pitfall in myeloid cells Leukemia (IF 12.8) Pub Date : 2024-07-16 Anna Sperk, Antje Gabriel, Daniela Koch, Abirami Augsburger, Victoria Sanchez, David Brockelt, Rupert Öllinger, Thomas Engleitner, Piero Giansanti, Romina Ludwig, Priska Auf der Maur, Wencke Walter, Torsten Haferlach, Irmela Jeremias, Roland Rad, Barbara Steigenberger, Bernhard Kuster, Ruth Eichner, Florian Bassermann
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PHF6 suppresses self-renewal of leukemic stem cells in AML Leukemia (IF 12.8) Pub Date : 2024-07-14 Sapana S. Jalnapurkar, Aishwarya S. Pawar, Subin S. George, Charles Antony, Patrick Somers, Jason Grana, Victoria K. Feist, Sandeep Gurbuxani, Vikram R. Paralkar
更新日期：2024-09-11
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