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Charting a path to health for all at net-zero emissions Lancet (IF 98.4) Pub Date : 2025-04-25 Judith Rodin, Jennifer R Bratburd, Noah Duff, Jonathan A Patz, Howard Frumkin, Catherine E Woteki, Sarah Whitmee, Michele Toplitz, Victor J Dzau, Andy Haines
No Abstract
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Navigating health financing cliffs: a new era in global health Lancet (IF 98.4) Pub Date : 2025-04-25 Kumanan Rasanathan, Maylene M Beltran, Alberta A Biritwum-Nyarko, Mark S Blecher, Mark Dybul, Hajime Inoue, Kelechi Ohiri, Walaiporn Patcharanarumol, Yogan Pillay, K Srinath Reddy, Minghui Ren, Zubin Cyrus Shroff, Bright Simons, Susan Sparkes, Kalipso Chalkidou
No Abstract
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NIH access bans imperil global scientific cooperation Lancet (IF 98.4) Pub Date : 2025-04-24 Bryant Furlow
No Abstract
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Can the FDA fulfil its mission with a smaller workforce? Lancet (IF 98.4) Pub Date : 2025-04-24 Susan Jaffe
No Abstract
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Pippa Tyrrell Lancet (IF 98.4) Pub Date : 2025-04-24 Georgina Ferry
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Research at the centre of UK health-care delivery to fix clinical academia Lancet (IF 98.4) Pub Date : 2025-04-24 Helena Marzo-Ortega
No Abstract
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Taiwan's national health care on the brink of systemic collapse Lancet (IF 98.4) Pub Date : 2025-04-24 Jing-Xing Li, Shu-Bai Hsu
No Abstract
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Ticagrelor monotherapy for acute coronary syndromes Lancet (IF 98.4) Pub Date : 2025-04-24 Chunguang Guo, Dan Shan, Zaoqu Liu, Fuchu He
No Abstract
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Ticagrelor monotherapy for acute coronary syndromes Lancet (IF 98.4) Pub Date : 2025-04-24 Anastasios Apostolos, Grigorios Tsigkas
No Abstract
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Ticagrelor monotherapy for acute coronary syndromes Lancet (IF 98.4) Pub Date : 2025-04-24 Chongquan Huang
No Abstract
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Ticagrelor monotherapy for acute coronary syndromes – Authors' reply Lancet (IF 98.4) Pub Date : 2025-04-24 Marco Valgimigli, Sung-Jin Hong, Felice Gragnano, Myeong-Ki Hong
No Abstract
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Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial Lancet (IF 98.4) Pub Date : 2025-04-24 Akhil Santhosh, Annie Baa, Sindhura Durga Chitikela
No Abstract
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Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial Lancet (IF 98.4) Pub Date : 2025-04-24 Dimitrios Moris, Pejman Radkani, Thomas Fishbein
No Abstract
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Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial Lancet (IF 98.4) Pub Date : 2025-04-24 Shouhui Yi, Jiao Lu, Jianchuan Deng, Zuojin Liu, Diguang Wen
No Abstract
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Pretransplantation optimisation for unresectable colorectal liver metastases: the TransMet trial – Authors' reply Lancet (IF 98.4) Pub Date : 2025-04-24
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-24
Strunk T, Molloy EJ, Mishra A, Bhutta ZA. Neonatal bacterial sepsis. Lancet 2024; 404: 277–93—In figure 1 of this Seminar, the teal key title has been updated to “Other neonatal disorders”. This correction has been made to the online version as of April 24, 2025.
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-24
Buonfrate D, Ferrari TCA, Adegnika AA, Russell Stothard J, Gobbi FG. Human schistosomiasis. Lancet 2025; 405: 658–70—In this Seminar, Ayola Akim Adegnika's name should have appeared as Prof A A Adegnika in the affiliations. This correction has been made to the online version as of April 24, 2025.
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-24
Hu X, Zhang J, Yang S, et al. Angiography-derived fractional flow reserve versus intravascular ultrasound to guide percutaneous coronary intervention in patients with coronary artery disease (FLAVOUR II): a multicentre, randomised, non inferiority trial. Lancet 2025; 405: 1491–504—In this Article, the spelling of author Shengxian Tu's name was incorrect. This correction has been made to the online
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-24
Amouzou A, Barros AJD, Requejo J, et al. The 2025 report of the Lancet Countdown to 2030 for women's, children's, and adolescents’ health: tracking progress on health and nutrition. Lancet 2025; 405: 1505–54—In this Review, Abdoulaye Maïga was missing from the author list and his details have been added. These corrections have been made to the online version as of April 24, 2025, and the printed version
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From crisis to opportunity: a united response to Trump's attacks on climate action Lancet (IF 98.4) Pub Date : 2025-04-21 Marina Romanello, Paul J Beggs, Wenjia Cai, Stella Hartinger, Tafadzwanashe Mabhaudhi, Kris A Murray, Joacim Rocklöv
No Abstract
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Relieve the suffering: palliative care for the next decade Lancet (IF 98.4) Pub Date : 2025-04-18 William E Rosa, Stephen Connor, Ghauri Aggarwal, Samy Alsirafy, Joanne Brennan, Helena Davies, Julia Downing, Betty Ferrell, Richard Harding, Felicia Marie Knaul, Emmanuel B K Luyirika, María M Marroquín, Joan Marston, Lukas Radbruch, M R Rajagopal, Libby Sallnow, Eric L Krakauer
No Abstract
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Prolonged grief disorder Lancet (IF 98.4) Pub Date : 2025-04-17 Clare Killikelly, Kirsten V Smith, Ningning Zhou, Holly G Prigerson, Mary-Frances O'Connor, Cyrille Kossigan Kokou-Kpolou, Paul A Boelen, Andreas Maercker
Prolonged grief disorder is a mental health disorder recently included in diagnostic manuals worldwide. This Review presents published research evidence in strong support for the current conceptualisation of prolonged grief disorder: a diagnosable mental health condition with core symptoms of yearning, preoccupation, or both, which is associated with symptoms of emotional pain, identity disturbances
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Safety and immunogenicity of a virus-like particle Chikungunya virus vaccine Lancet (IF 98.4) Pub Date : 2025-04-17 Ernesto T A Marques, Donald S Burke
No Abstract
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After release, another struggle: Syria's ex-detainees Lancet (IF 98.4) Pub Date : 2025-04-17 Cosette Molijn
Section snippets An unwelcoming realityThose who survive detention are faced with a harsh reality once outside. Many return to heavily damaged or destroyed neighbourhoods, have financial problems, and are unable to find work in Syria's devasted economy. Family members who awaited the return of their loved ones for years might expect men or sons to retake their role as breadwinners, although they often
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Humanitarians warn over assistance for mine victims Lancet (IF 98.4) Pub Date : 2025-04-17 John Zarocostas
No Abstract
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Aid cuts prompting a shift in migration policy Lancet (IF 98.4) Pub Date : 2025-04-17 Sharmila Devi
No Abstract
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My autistic meltdown: the impact of autistic sensory needs Lancet (IF 98.4) Pub Date : 2025-04-17 Mary Doherty
No Abstract
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Susan Franklin Wood Lancet (IF 98.4) Pub Date : 2025-04-17 Andrew Green
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Population health and a representative US health-care workforce Lancet (IF 98.4) Pub Date : 2025-04-17 Vincent Guilamo-Ramos, Marco Thimm-Kaiser, Adam Benzekri, Danielle McCamey
No Abstract
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Medical research funding cuts will save money and spend lives Lancet (IF 98.4) Pub Date : 2025-04-17 Cameron John Sabet
No Abstract
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Rehabilitation under fire: insights from SUMC Lancet (IF 98.4) Pub Date : 2025-04-17 Alan Friedman, Cheryl Benjamin, Iuly Treger
No Abstract
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The need for expansion of global collaborations on AI in oncology Lancet (IF 98.4) Pub Date : 2025-04-17 Qiang Liu, Chuying Huang, Ge Zhan, Yujing Guan, Shenglong Li
No Abstract
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Finalising the WHO Pandemic Agreement for a safer future Lancet (IF 98.4) Pub Date : 2025-04-17 Walid Ammar, Christopher Baggoley, Felicity Harvey, Yasmin Ali Haque, Jeremy Konyndyk, Youngmee Jee, Samba Sow, Elhadj As Sy, Theresa Tam
No Abstract
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Irrigation efficacy in CSDH surgery: the FINISH trial Lancet (IF 98.4) Pub Date : 2025-04-17 Aaron Lawson McLean
No Abstract
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Irrigation efficacy in CSDH surgery: the FINISH trial – Authors' reply Lancet (IF 98.4) Pub Date : 2025-04-17 Rahul Raj, Kimmo Lönnrot, Teppo L N Järvinen
No Abstract
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Need for VA-ECMO after heart transplantation with HOPE Lancet (IF 98.4) Pub Date : 2025-04-17 Jose Gonzalez-Costello, Snehal R Patel, Ulrich P Jorde
No Abstract
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Need for VA-ECMO after heart transplantation with HOPE – Authors' reply Lancet (IF 98.4) Pub Date : 2025-04-17 Filip Rega, Guillaume Lebreton, Göran Dellgren, Andreas Wallinder
No Abstract
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Efficacy and safety of topical delgocitinib cream versus oral alitretinoin capsules in adults with severe chronic hand eczema (DELTA FORCE): a 24-week, randomised, head-to-head, phase 3 trial Lancet (IF 98.4) Pub Date : 2025-04-16 Ana Maria Giménez-Arnau, Andreas Pinter, Wiebke Sondermann, Ziad Reguiai, Richard Woolf, Charles Lynde, Franz J Legat, Antonio Costanzo, Juan F Silvestre, Natja Mellerup, Marie Louise Østerdal, Ursula Plohberger, Lasse Ryttig, Andrea Bauer
BackgroundChronic hand eczema is a heterogeneous, fluctuating, and long-lasting disease affecting the hands and wrists that substantially affects quality of life. For severe chronic hand eczema, topical corticosteroids are often unsatisfactory and systemic treatment can be required. The aim of the head-to-head, phase 3 DELTA FORCE trial was to evaluate the efficacy and safety of topical delgocitinib
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Chronic hand eczema treatment: exploring topical JAK inhibition further Lancet (IF 98.4) Pub Date : 2025-04-16 Yael Renert-Yuval
No Abstract
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Negative pressure wound therapy versus usual care in patients with surgical wound healing by secondary intention in the UK (SWHSI-2): an open-label, multicentre, parallel-group, randomised controlled trial Lancet (IF 98.4) Pub Date : 2025-04-15 Catherine Arundel, Laura Mandefield, Caroline Fairhurst, Kalpita Baird, Athanasios Gkekas, Pedro Saramago, Ian Chetter
BackgroundSurgical wound healing by secondary intention (SWHSI) presents a substantial management and financial challenge. Negative pressure wound therapy (NPWT) has increasingly been used as a treatment despite an absence of comparative evidence of effectiveness. We evaluated the effectiveness of NPWT compared with usual care for improving time to wound healing in patients with an SWHSI. MethodsWe
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Is negative pressure wound therapy beneficial for post-surgical wounds? Lancet (IF 98.4) Pub Date : 2025-04-15 Kenji Inaba, Matthew Martin
No Abstract
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A proposed framework for monitoring and evaluating progress at the intersection of women, power, and cancer Lancet (IF 98.4) Pub Date : 2025-04-15 Elise M Garton, Gavin Allman, Hyo Sook Bae, Kalina Duncan, Ibithal Fadhil, Nazik Hammad, Shirin Heidari, Erica Liebermann, Meritxell Mallafré-Larrosa, Jennifer Moodley, Rachel Nugent, Isabelle Soerjomataram, Carolyn D Taylor, Karla Unger-Saldaña, Verna Vanderpuye, Ophira Ginsburg
Section snippets ContributorsEMG, GA, HSB, IF, NH, EL, MM-L, JM, RN, IS, KUS, VV, SH, and OG were responsible for conceptualisation of the manuscript. EMG, HSB, MM-L, and OG were responsible for the methods and project administration. EMG, HSB, and MM-L completed formal analysis. EMG completed visualisation and the original draft. OG was responsible for supervision of the work. All authors contributed
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CONSORT 2025 statement: updated guideline for reporting randomised trials Lancet (IF 98.4) Pub Date : 2025-04-14 Sally Hopewell, An-Wen Chan, Gary S Collins, Asbjørn Hróbjartsson, David Moher, Kenneth F Schulz, Ruth Tunn, Rakesh Aggarwal, Michael Berkwits, Jesse A Berlin, Nita Bhandari, Nancy J Butcher, Marion K Campbell, Runcie C W Chidebe, Diana Elbourne, Andrew Farmer, Dean A Fergusson, Robert M Golub, Steven N Goodman, Tammy C Hoffmann, Isabelle Boutron
Well designed and properly executed randomised trials are considered the most reliable evidence on the benefits of healthcare interventions. However, there is overwhelming evidence that the quality of reporting is not optimal. The CONSORT (Consolidated Standards of Reporting Trials) statement was designed to improve the quality of reporting and provides a minimum set of items to be included in a report
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Oral gepotidacin for the treatment of uncomplicated urogenital gonorrhoea (EAGLE-1): a phase 3 randomised, open-label, non-inferiority, multicentre study Lancet (IF 98.4) Pub Date : 2025-04-14 Jonathan D C Ross, Janet Wilson, Kimberly A Workowski, Stephanie N Taylor, David A Lewis, Sally Gatsi, William Flight, Nicole E Scangarella-Oman, Charles Jakielaszek, Dan Lythgoe, Marcy Powell, Salim Janmohamed, Judith Absalon, Caroline Perry
BackgroundGepotidacin, a first-in-class, bactericidal, triazaacenaphthylene antibacterial that inhibits bacterial DNA replication, was shown to be efficacious and well tolerated in the treatment of uncomplicated urinary tract infections. We evaluated the efficacy and safety of gepotidacin for the treatment of uncomplicated urogenital gonorrhoea. MethodsEAGLE-1 (NCT04010539) was a phase 3, open-label
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Gepotidacin shows promise for the treatment of uncomplicated gonorrhoea Lancet (IF 98.4) Pub Date : 2025-04-14 Magnus Unemo, Teodora Wi
No Abstract
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Why and how academic medicine must champion diversity, equity, inclusion, and accessibility Lancet (IF 98.4) Pub Date : 2025-04-12 Arghavan Salles, Ananya Tina Banerjee, Wendy Caceres, Mamas Mamas, Oni Blackstock
No Abstract
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-12
Sidibe M, Makgoba TC, Bishop Paul, et al. Accelerating domestic investments to end AIDS in Africa. Lancet 2025; Published Online April 8, 2025 https://doi.org/10.1016/S0140-6736(25)00685-3—In this Correspondence, paragraph four has been updated to clarify that amfAR conducted the research using World Bank Development Indicators on health spending. This correction has been made to the online version
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Department of Error Lancet (IF 98.4) Pub Date : 2025-04-10
Cluver L, Makangila G, Hillis S, et al. Protecting Africa's children from extreme risk: a runway of sustainability for PEPFAR programmes. Lancet 2025; published online April 8. https://doi.org/10.1016/S0140-6736(25)00401-5—In figure 2B of this Health Policy, the colour scale was inverted. This correction has been made to the online version as of April 10, 2025, and will be made to the printed version
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Accelerating vaccine development in Africa: lessons from HIV research Lancet (IF 98.4) Pub Date : 2025-04-10 Nicaise Ndembi, Shelly Karuna, Jessica Cowden, Alberto Cagigi, Anthony Pilorget, Amber Moodley, Julie Ake, Sandhya Vasan, Nelson Michael, Jerome H Kim
No Abstract
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Clinical presentation and epidemiological assessment of confirmed human mpox cases in DR Congo: a surveillance-based observational study Lancet (IF 98.4) Pub Date : 2025-04-10 Emile Malembi, Roser Escrig-Sarreta, Jackie Ntumba, Camila G Beiras, Robert Shongo, Justin Bengehya, Charles Nselaka, Elisabeth Pukuta, Daniel Mukadi-Bamuleka, Noëlla Mulopo-Mukanya, Xinying Leng, Clara Pérez-Mañá, Cristina Galván-Casas, Susana Muñoz, Steeven Bilembo-Kitwanda, Pierre Kitha, Vivi Maketa, Patrick Mitashi, Aruna Abedi, Justus Nsio, Jacques Daudi Cinyabuuma
BackgroundMpox, caused by the monkeypox virus, is a serious public health threat in Africa, especially in DR Congo. Previously limited to endemic areas with clade 1a, monkeypox virus has recently spread to non-endemic regions, where clade 1b has emerged. This study provides a clinical comparison of mpox cases in DR Congo regions where clade 1a and clade 1b are prevalent. MethodsWe conducted a retrospective
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Integrating research into surveillance: enhancing the response to mpox Lancet (IF 98.4) Pub Date : 2025-04-10 Francine Ntoumi, Nathalie Strub-Wourgaft
No Abstract
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Towards a greener, healthier Paris Lancet (IF 98.4) Pub Date : 2025-04-10 Jacqui Thornton
No Abstract
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“Staggering” scale of sexual violence in Sudan Lancet (IF 98.4) Pub Date : 2025-04-10 Sharmila Devi
No Abstract
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On a mission to reinvigorate anatomy | Gabriel Weston, ALIVE: An Alternative Anatomy, Jonathan Cape/Vintage (2025), p. 304, £20·00, ISBN: 9781787330603 Lancet (IF 98.4) Pub Date : 2025-04-10 Rachel Clarke
No Abstract
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Annihilation: a fragile body in a sick society | Michel Houellebecq, Annihilation, Shaun Whiteside (Ed.), Picador (2024), p. 544, £22·00, ISBN: 9781035026395 Lancet (IF 98.4) Pub Date : 2025-04-10 Joseph Moody
No Abstract
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A taste of your own medicine: the experience of a transplant Lancet (IF 98.4) Pub Date : 2025-04-10 Havi Carel
No Abstract