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Prognosticating Residual Dysplasia at Skeletal Maturity Following Closed Reduction for Developmental Dysplasia of the Hip: A Long-Term Study with an Average 20-Year Follow-up. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-18 Janus Siu Him Wong,Evelyn Eugenie Kuong,Michael Kai Tsun To,Alfred Lok Hang Lee,Noah Lok Wah So,Wang Chow
BACKGROUND Patients with developmental dysplasia of the hip (DDH) are at risk for residual acetabular dysplasia even after successful closed reduction. The aim of this study was to identify predictors of long-term outcomes in order to guide prognostication and management. METHODS Patients who were treated for DDH at 2 institutions between 1970 and 2010 and had follow-up until skeletal maturity were
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Liposomal Bupivacaine Does Not Decrease Postoperative Pain in Patients with Intracapsular Femoral Neck Fracture Treated with Hemiarthroplasty: HEAT-A Randomized, Controlled Trial. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-18 Kevin K Kang,Lucas Voyvodic,Daniel Komlos,Samuel Swiggett,Mitchell K Ng
BACKGROUND Liposomal bupivacaine (LB) is a long-lasting local anesthetic agent that was developed for use in the surgical setting to help manage postoperative pain. The objective of this study was to evaluate the effect of LB on postoperative pain, function, and overall hospital course in patients with intracapsular hip fractures who were treated with hip hemiarthroplasty. METHODS This was a single-center
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Minimally Invasive Surgery for Posterior Atlantoaxial Lateral Mass Joint Fusion (MIS-PALF): A Muscle-Sparing Procedure for Atlantoaxial Instability or Dislocation. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-18 Kan-Lin Hung,Yong Lu,Yinglun Tian,Shilin Xue,Guodong Gao,Qiyue Gao,Nanfang Xu,Shenglin Wang
BACKGROUND Conventional surgical procedures for atlantoaxial instability or dislocation (AAI/D) have been associated with a high prevalence of postoperative occipitocervical pain and dysfunction, as well as substantial perioperative blood loss. We hypothesized that minimally invasive surgery for posterior atlantoaxial lateral mass joint fusion (MIS-PALF), a procedure that can largely avoid disruption
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The T4-L1-Hip Axis: Sagittal Spinal Realignment Targets in Long-Construct Adult Spinal Deformity Surgery: Early Impact. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-18 Jeffrey Hills,Gregory M Mundis,Eric O Klineberg,Justin S Smith,Breton Line,Jeffrey L Gum,Themistocles S Protopsaltis,D Kojo Hamilton,Alex Soroceanu,Robert Eastlack,Pierce Nunley,Khaled M Kebaish,Lawrence G Lenke,Richard A Hostin,Munish C Gupta,Han Jo Kim,Christopher P Ames,Douglas C Burton,Christopher I Shaffrey,Frank J Schwab,Virginie Lafage,Renaud Lafage,Shay Bess,Michael P Kelly,
BACKGROUND Our understanding of the relationship between sagittal alignment and mechanical complications is evolving. In normal spines, the L1-pelvic angle (L1PA) accounts for the magnitude and distribution of lordosis and is strongly associated with pelvic incidence (PI), and the T4-pelvic angle (T4PA) is within 4° of the L1PA. We aimed to examine the clinical implications of realignment to a normal
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Patient Factors Associated with 10-Year Survival After Arthroplasty for Hip Fracture: A Population-Based Study in Ontario, Canada. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-18 Mina Tohidi,George Grammatopoulos,Stephen M Mann,Alexandra Pysklywec,Patti A Groome
BACKGROUND The aim of this study was to describe long-term (10-year) patient survival after arthroplasty for hip fracture and to determine what patient factors are associated with that outcome. METHODS We performed a retrospective cohort analysis of patients ≥60 years old who underwent either hemiarthroplasty or total hip arthroplasty for femoral neck fracture between 2002 and 2009. We used routinely
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Degradomics defines proteolysis information flow from human knee osteoarthritis cartilage to matched synovial fluid and the contributions of secreted proteases ADAMTS5, MMP13 and CMA1 to articular cartilage breakdown Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-16 Sumit Bhutada, Anna Hoyle, Nicolas S. Piuzzi, Suneel S. Apte
Proteolytic cartilage extracellular matrix breakdown is a major mechanism of articular cartilage loss in osteoarthritis (OA) pathogenesis. We sought to determine the overlap of proteolytic peptides in matched knee OA cartilage and synovial fluid on a proteome-wide scale to increase the prospective biomarker repertoire and to attribute proteolytic cleavages to specific secreted proteases.
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Effect of arthroscopic partial meniscectomy on structural degeneration of the knee – A 5-year MRI-based follow-up of the placebo-surgery controlled FIDELITY (Finnish Degenerative Meniscus Lesion Study) trial Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-12 Niko Sillanpää, Marika Iivanainen, Aleksandra Turkiewicz, Raine Sihvonen, Mika Paavola, Simo Taimela, Teppo L.N. Järvinen, Martin Englund
To assess the 5-year effects of arthroscopic partial meniscectomy (APM) vs. placebo surgery on the development of the structural changes of the knee by magnetic resonance imaging (MRI).
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Antihistamine use and osteoarthritis or joint pain Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-12 Aleksandra Turkiewicz, Clara Hellberg, Andrea Dell’Isola, Martin Englund
Antihistamines have been reported to be linked with less pain in osteoarthritis. We aimed to estimate associations between antihistamine use and three outcomes: prevalent osteoarthritis, current joint pain, and developing osteoarthritis.
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The relationships between patellofemoral bone remodeling, cartilage composition, and vertical loading rate: PET/MRI in isolated patellofemoral osteoarthritis Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-12 Rupsa Bhattacharjee, Eric Hammond, Ngarmsrikam Chotigar, Zehra Akkaya, Fei Jiang, Emma Bahroos, Misung Han, Spencer Behr, Matthew D. Bucknor, Richard B. Souza, Valentina Pedoia, Sharmila Majumdar
Loading is invariably an important factor of consideration for understanding the causality flow and parallel existence of articular cartilage and subchondral bone changes. The goal of this study was to investigate the patterns of subregional 18NaF-SUV vs. T1p-T2 associations and vertical ground reaction force loading rates; in isolated patellofemoral-joint-osteoarthritis (PFJ-OA) patients.
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Thirty-five Years of Reporting of Sex and Race in Clinical Studies of U.S. FDA-Authorized Orthopaedic Devices. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-12 Hongying Jiang,Katherine Kavlock,Qin Li,Shruti Mistry,Valerie Hermes,Alonza Gibbs,Elizabeth Adegboyega-Panox,Raquel Peat
BACKGROUND At the U.S. Food and Drug Administration (FDA), the mission of the Center for Devices and Radiological Health (CDRH) is to ensure that all patients and providers have timely and continued access to safe, effective, and high-quality medical devices and safe radiation-emitting products. Although the CDRH has observed enrollment differences in some clinical trials, no systematic analysis has
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Levels of Synovial Fluid Inflammatory Biomarkers on Day of Arthroscopic Partial Meniscectomy Predict Long-Term Outcomes and Conversion to TKA: A 10-Year Mean Follow-up Study. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-12 Michael R Moore,Brittany DeClouette,Isabel Wolfe,Matthew T Kingery,Carlos Sandoval-Hernandez,Ryan Isber,Thorsten Kirsch,Eric J Strauss
BACKGROUND The purpose of the present study was to evaluate the relationships of the concentrations of pro- and anti-inflammatory biomarkers in the knee synovial fluid at the time of arthroscopic partial meniscectomy (APM) to long-term patient-reported outcomes (PROs) and conversion to total knee arthroplasty (TKA). METHODS A database of patients who underwent APM for isolated meniscal injury was analyzed
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What's Important: Engaging Meaningfully with Sustainability Efforts as an Orthopaedic Surgeon. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-11 Laura L Bellaire
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Feasibility of the Non-Window-Type 3D-Printed Porous Titanium Cage in Posterior Lumbar Interbody Fusion: A Randomized Controlled Multicenter Trial. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-11 Dae-Woong Ham,Sang-Min Park,Youngbae B Kim,Dong-Gune Chang,Jae Jun Yang,Byung-Taek Kwon,Kwang-Sup Song
BACKGROUND Three-dimensionally printed titanium (3D-Ti) cages can be divided into 2 types: window-type cages, which have a void for bone graft, and non-window-type cages without a void. Few studies have investigated the necessity of a void for bone graft in fusion surgery. Therefore, the present study assessed the clinical and radiographic outcomes of window and non-window-type 3D-Ti cages in single-level
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Is 18F-fluoride PET/CT an Accurate Tool to Diagnose Loosening After Total Joint Arthroplasty? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-11 Caroline Sköld,Jens Sörensen,Anders Brüggemann,Nils P Hailer
BACKGROUND Several studies using positron emission tomography (PET) show highly elevated periprosthetic bone uptake of fluorine-18 sodium fluoride (18F-fluoride), suggestive of implant loosening after arthroplasty. Focus so far has been on qualitative but not on quantitative assessment. There is also a lack of intraoperative confirmation of preoperative 18F-fluoride PET findings. Although the method
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Effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis based on large randomized trials: A systematic review and network meta-analysis Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-10 Tiago V. Pereira, Pakeezah Saadat, Pavlos Bobos, Samir M. Iskander, Nicolas S. Bodmer, Martina Rudnicki, Henry Dan Kiyomoto, Thais Montezuma, Matheus O. Almeida, Rishi Bansal, Pai-Shan Cheng, Jason W. Busse, Alex J. Sutton, Peter Tugwell, Gillian A. Hawker, Peter Jüni, Bruno R. da Costa
To quantify the effectiveness and safety of intra-articular interventions for knee and hip osteoarthritis (OA) through a systematic review and Bayesian random-effects network meta-analysis.
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Letter to the Editor: A Conversation With … Emily Wilson PhD, Contemporary Interpreter of the Iliad, on Listening, Hearing, and Communicating. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-10 Lyn Jones
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Medicolegal Sidebar: Taking Care of Professional Athletes-Is It Worth the Risk? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-10 B Sonny Bal
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No Association Between Growth Hormone Therapy and Upper Extremity Physeal Tension Injuries: A Matched Case-control Study. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-10 Ruth H Jones,Samuel A Beber,Akshitha Adhiyaman,Olivia C Tracey,Emilie Lijesen,Daniel W Green,Peter D Fabricant
BACKGROUND Recent evidence has identified a strong association between growth hormone therapy and physeal injuries in the lower extremity; however, few studies have investigated this association in the upper extremity. QUESTIONS/PURPOSES (1) Do pediatric patients with physeal tension injuries of the shoulder and elbow have higher odds of having exposure to recombinant growth hormone therapy than matched
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Which Interventions Are Effective in Treating Sleep Disturbances After THA or TKA? A Systematic Review. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-09 Emily Pilc,Sri Vibhaav Bankuru,Sarah F Brauer,John W Cyrus,Nirav K Patel
BACKGROUND Poor sleep quality is a common complaint after total joint arthroplasty (TJA), and it is associated with reports of higher pain and worse functional outcomes. Several interventions have been investigated with the intent to reduce the incidence of postoperative sleep disturbance with varying effectiveness. An aggregate of the best available evidence, along with an evaluation of the quality
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Osteopontin deficiency promotes cartilaginous endplate degeneration by enhancing the NF-κB signaling to recruit macrophages and activate the NLRP3 inflammasome Bone Res. (IF 14.3) Pub Date : 2024-09-06 Yanqiu Wang, Wanqian Zhang, Yi Yang, Jinghao Qin, Ruoyu Wang, Shuai Wang, Wenjuan Fu, Qin Niu, Yanxia Wang, Changqing Li, Hongli Li, Yue Zhou, Minghan Liu
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Patients' Preferences for Bone-Anchored Prostheses After Lower-Extremity Amputation: A 2-Center Discrete Choice Experiment in The Netherlands (PREFER-BAP-1). J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-06 Gabriel-Kyrillos M Saleib,Marcel F Jonker,Mark G Van Vledder,Michael H J Verhofstad,Maria A Paping,Ruud A Leijendekkers,Oscar J F Van Waes
BACKGROUND The rising popularity and use of a bone-anchored prosthesis (BAP) involving an osseointegrated implant for patients with lower-limb amputations experiencing socket-related issues have led to increased interest in the measurement of clinical and functional outcomes. However, the value of BAP treatment characteristics from the patient perspective has not yet been investigated. This study aimed
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Demographics, Indications, and Revision Rates for Radial Head Arthroplasty: Analysis of Data from the Australian Orthopaedic Association National Joint Replacement Registry. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-06 Narinder Kumar,Belinda J Gabbe,Richard S Page,Sze-Ee Soh,David R J Gill,Dylan Harries,Ilana N Ackerman
BACKGROUND Population-level data from national arthroplasty registries enable the use and outcomes of arthroplasty procedures to be monitored over time. This study aimed to describe the demographics, indications, and outcomes (up to 15 years) for radial head arthroplasty (RHA) procedures in Australia, as well as the factors associated with an increased likelihood of revision. METHODS Individual-level
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"Dr. AI Will See You Now": How Do ChatGPT-4 Treatment Recommendations Align With Orthopaedic Clinical Practice Guidelines? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-06 Tanios Dagher,Emma P Dwyer,Hayden P Baker,Senthooran Kalidoss,Jason A Strelzow
BACKGROUND Artificial intelligence (AI) is engineered to emulate tasks that have historically required human interaction and intellect, including learning, pattern recognition, decision-making, and problem-solving. Although AI models like ChatGPT-4 have demonstrated satisfactory performance on medical licensing exams, suggesting a potential for supporting medical diagnostics and decision-making, no
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Hydroxychloroquine and a low antiresorptive activity bisphosphonate conjugate prevent and reverse ovariectomy-induced bone loss in mice through dual antiresorptive and anabolic effects Bone Res. (IF 14.3) Pub Date : 2024-09-05 Zhenqiang Yao, Akram Ayoub, Venkatesan Srinivasan, Jun Wu, Churou Tang, Rong Duan, Aleksa Milosavljevic, Lianping Xing, Frank H. Ebetino, Alison J. Frontier, Brendan F. Boyce
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No Short-term Clinical Benefit to Bovine Collagen Implant Augmentation in Primary Rotator Cuff Repair: A Matched Retrospective Study. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-05 Mark Haft,Steve S Li,Zachary C Pearson,Uzoma Ahiarakwe,Amie F Bettencourt,Umasuthan Srikumaran
BACKGROUND Bovine bioinductive collagen implants (herein, "bovine collagen implant") can be used to augment rotator cuff repair. Concern exists that these bovine collagen implants may not yield clinical benefits and may actually increase postoperative stiffness and the need for reoperation. QUESTIONS/PURPOSES Among patients who underwent primary rotator cuff repair with or without a bovine collagen
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Not the Last Word: Restrictive Covenants Can be Liberating. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-05 Joseph Bernstein
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Targeting Fascin1 maintains chondrocytes phenotype and attenuates osteoarthritis development Bone Res. (IF 14.3) Pub Date : 2024-09-04 Panpan Yang, Yun Xiao, Liangyu Chen, Chengliang Yang, Qinwei Cheng, Honghao Li, Dalin Chen, Junfeng Wu, Zhengquan Liao, Changsheng Yang, Chong Wang, Hong Wang, Bin Huang, Ee Ke, Xiaochun Bai, Kai Li
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Bone targeted nano-drug and nano-delivery Bone Res. (IF 14.3) Pub Date : 2024-09-04 Yilun Wu, Bing Sun, Ying Tang, Aining Shen, Yanlin Lin, Xiaohui Zhao, Jingui Li, Michael J. Monteiro, Wenyi Gu
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Evidence-based hierarchy of pain outcome measures for osteoarthritis clinical trials and meta-analyses Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-04 Pakeezah Saadat, Tiago V. Pereira, Rahim Lalji, Henry D. Kiyomoto, Nicolas S. Bodmer, Pavlos Bobos, Samir Iskander, Areti-Angeliki Veroniki, Gillian A. Hawker, Alex J. Sutton, Peter Jüni, Bruno R. da Costa
To rank commonly used patient-reported outcome measures (PROMs) for assessing pain in osteoarthritis trials according to their assay sensitivity, defined as the ability of a PROM to distinguish an effective from a less effective intervention or placebo, proposing a hierarchy for PROM selection in trials and data-extraction in meta-analyses.
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A Call to Start Implementing the Results of High-Quality Randomized Trials in Daily Orthopaedic Practice: Commentary on an article by Neil J. White, MD, et al.: "Low-Intensity Pulsed Ultrasound Versus Sham in the Treatment of Operatively Managed Scaphoid Nonunions. The SNAPU Randomized Controlled Trial". J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-04 Tom J Crijns
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Cementless Oxford Unicompartmental Knee Replacements: More Data, More Questions: Commentary on an article by Hasan R. Mohammad, MRCS, MRes(Dist), DPhil(Oxon), et al.: "A Matched Comparison of Implant and Functional Outcomes of Cemented and Cementless Unicompartmental Knee Replacements. A Study from the National Registry for England, Wales, Northern Ireland and the Isle of Man and the Hospital Episode J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-04 Aaron G Chen,Michael S Reich
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Periprosthetic Joint Infection and Mortality: A Call to Action. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-04 Mohit Bhandari
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What's Important (Arts & Humanities): America's Wild Horses. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-03 Alexander J Ghanayem
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Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-03 Stephen M Gillinov,Maxwell Modrak,Nancy Park,Peter F Monahan,Christopher V Wilhelm,Michael S Lee,Ronak J Mahatme,Scott Fong,Jay Moran,Jonathan N Grauer,Andrew E Jimenez
BACKGROUND Patients with hemophilia A can develop joint hemarthroses, degenerative changes, and eventually undergo total shoulder arthroplasty (TSA). Few data exist concerning complications and prosthesis survival after TSA in this population. QUESTIONS/PURPOSES (1) Is hemophilia A associated with more bleeding and thromboembolic adverse events after TSA relative to matched controls? (2) Is 5-year
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CORR Insights®: Taper Junction Subsidence Occurs in Modular Tumor Endoprostheses: How Concerned Should We Be? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-03 Magdalena Maria Gilg
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Editorial: How to Make the Most of Open Notes. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-03 Seth S Leopold,Clare M Rimnac,David Ring
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CORR® Curriculum-Orthopaedic Education: Artificial Intelligence and Surgical Assessment. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-03 Paul J Dougherty,Pamela Andreatta
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What Are the Complications, Reconstruction Survival, and Functional Outcomes of Modular Prosthesis and Allograft-prosthesis Composite for Proximal Femur Reconstruction in Children With Primary Bone Tumors? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-09-03 Ahmed Atherley O'Meally,Giovanni Rizzi,Monica Cosentino,Hisaki Aiba,Ayano Aso,Konstantina Solou,Laura Campanacci,Federica Zuccheri,Barbara Bordini,Davide Maria Donati,Costantino Errani
BACKGROUND Proximal femur reconstruction after bone tumor resection in children is a demanding surgery for orthopaedic oncologists because of the small bone size and possible limb-length discrepancy at the end of skeletal growth owing to physis loss. The most commonly used reconstruction types used for the proximal femur are modular prostheses and allograft-prosthesis composites. To our knowledge,
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Comparison of weight loss interventions in overweight and obese adults with knee osteoarthritis: A systematic review and network meta-analysis of randomized trials Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-02 Arashi Shahid, Aricia Jieqi Thirumaran, Robin Christensen, Venkatesha Venkatesha, Marius Henriksen, Jocelyn L. Bowden, David J. Hunter
To ascertain the comparative effectiveness of weight-loss strategies for osteoarthritis (OA) to develop rational treatment algorithms aimed at improving OA-related symptoms in overweight/obese individuals. Medline, Embase, CINAHL, Scopus, and Web of Science were searched from inception to June 2023 for observational studies and randomized trials. Network meta-analyses were performed using a frequentist
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Dysregulated neutrophil extracellular traps and haemostatic biomarkers as diagnostic tools and therapeutic targets in periprosthetic joint infection. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Julia Oto,Raquel Herranz,Manuel Fuertes,Emma Plana,Patricia Verger,Francisco Baixauli,José V Amaya,Pilar Medina
Aims Bacterial infection activates neutrophils to release neutrophil extracellular traps (NETs) in bacterial biofilms of periprosthetic joint infections (PJIs). The aim of this study was to evaluate the increase in NET activation and release (NETosis) and haemostasis markers in the plasma of patients with PJI, to evaluate whether such plasma induces the activation of neutrophils, to ascertain whether
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Understanding the mechanism of injury and fracture pattern of paediatric triplane ankle fractures versus adult trimalleolar fractures. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Jasper Prijs,Jaideep Rawat,Kaj Ten Duis,Nick Assink,Jorrit S Harbers,Job N Doornberg,Bhavin Jadav,Ruurd L Jaarsma,Frank F A IJpma
Aims Paediatric triplane fractures and adult trimalleolar ankle fractures both arise from a supination external rotation injury. By relating the experience of adult to paediatric fractures, clarification has been sought on the sequence of injury, ligament involvement, and fracture pattern of triplane fractures. This study explores the similarities between triplane and trimalleolar fractures for each
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Outcomes of fixed versus mobile-bearing medial unicompartmental knee arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Kevin B Fricka,Eric J Wilson,Alexander V Strait,Henry Ho,Robert H Hopper,William G Hamilton,Robert A Sershon
Aims The optimal bearing surface design for medial unicompartmental knee arthroplasty (UKA) remains controversial. The aim of this study was to compare outcomes of fixed-bearing (FB) and mobile-bearing (MB) UKAs from a single high-volume institution. Methods Prospectively collected data were reviewed for all primary cemented medial UKAs performed by seven surgeons from January 2006 to December 2022
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Early Motion and Directed Exercise (EMADE) following ankle fracture fixation: a pragmatic randomized controlled trial. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Paul A Matthews,Brigitte E Scammell,Tim A Coughlin,Jessica Nightingale,Ben J Ollivere
Aims This study aimed to compare the outcomes of two different postoperative management approaches following surgical fixation of ankle fractures: traditional cast immobilization versus the Early Motion and Directed Exercise (EMADE) programme. Methods A total of 157 patients aged 18 years or older who underwent successful open reduction and internal fixation (ORIF) of Weber B (AO44B) ankle fractures
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Management of zone 2 fifth metatarsal fractures varies based on treating specialty. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Matthew T Kingery,Manasa L Kadiyala,Raymond Walls,Abhishek Ganta,Sanjit R Konda,Kenneth A Egol
Aims This study evaluated the effect of treating clinician speciality on management of zone 2 fifth metatarsal fractures. Methods This was a retrospective cohort study of patients with acute zone 2 fifth metatarsal fractures who presented to a single large, urban, academic medical centre between December 2012 and April 2022. Zone 2 was the region of the fifth metatarsal base bordered by the fourth
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Survivorship, complications, and functional outcomes of uncemented distal femoral endoprosthesis with short, curved stem for patients with bone tumours. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Taojun Gong,Minxun Lu,Hongtao Sheng,Zhuangzhuang Li,Yong Zhou,Yi Luo,Li Min,Chongqi Tu
Aims Endoprosthetic reconstruction following distal femur tumour resection has been widely advocated. In this paper, we present the design of an uncemented endoprosthesis system featuring a short, curved stem, with the goal of enhancing long-term survivorship and functional outcomes. Methods This study involved patients who underwent implantation of an uncemented distal femoral endoprosthesis with
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Efficacy and safety of commonly used thromboprophylaxis agents following hip and knee arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Tim Cheok,Alexander Beveridge,Morgan Berman,Martin Coia,Alexander Campbell,Tycus T S Tse,Job N Doornberg,Ruurd L Jaarsma
Aims We investigated the efficacy and safety profile of commonly used venous thromboembolism (VTE) prophylaxis agents following hip and knee arthroplasty. Methods A systematic search of PubMed, Embase, Cochrane Library, Web of Science, and OrthoSearch was performed. Prophylaxis agents investigated were aspirin (< 325 mg and ≥ 325 mg daily), enoxaparin, dalteparin, fondaparinux, unfractionated heparin
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The current role of CT in total knee arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Fabio Mancino,Andreas Fontalis,Babar Kayani,Ahmed Magan,Ricci Plastow,Fares S Haddad
Advanced 3D imaging and CT-based navigation have emerged as valuable tools to use in total knee arthroplasty (TKA), for both preoperative planning and the intraoperative execution of different philosophies of alignment. Preoperative planning using CT-based 3D imaging enables more accurate prediction of the size of components, enhancing surgical workflow and optimizing the precision of the positioning
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Long-term outcomes of anterior latissimus dorsi tendon transfer for irreparable subscapularis tears. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Chang H Baek,Jung G Kim,Bo T Kim
Aims Favourable short-term outcomes have been reported following latissimus dorsi tendon transfer for patients with an irreparable subscapularis (SSC) tendon tear. The aim of this study was to investigate the long-term outcomes of this transfer in these patients. Methods This was a retrospective study involving 30 patients with an irreparable SSC tear and those with a SSC tear combined with a reparable
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A new method for evaluating radial neck fractures based on Judet classification. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Yi C Wang,Jiao J Song,Ting T Li,Dan Yang,Zhi B Lv,Zhen Y Wang,Zi M Zhang,Yi Luo
Aims To propose a new method for evaluating paediatric radial neck fractures and improve the accuracy of fracture angulation measurement, particularly in younger children, and thereby facilitate planning treatment in this population. Methods Clinical data of 117 children with radial neck fractures in our hospital from August 2014 to March 2023 were collected. A total of 50 children (26 males, 24 females
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Tendon transfers for the management of irreparable subscapularis tears. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Ignacio De Rus Aznar,José L Ávila Lafuente,Abdul-Ilah Hachem,Jorge Díaz Heredia,Jean Kany,Bassem Elhassan,Miguel Á Ruiz Ibán
Rotator cuff pathology is the main cause of shoulder pain and dysfunction in older adults. When a rotator cuff tear involves the subscapularis tendon, the symptoms are usually more severe and the prognosis after surgery must be guarded. Isolated subscapularis tears represent 18% of all rotator cuff tears and arthroscopic repair is a good alternative primary treatment. However, when the tendon is deemed
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Comparing the risk of reoperation between pneumatic tourniquet and non-tourniquet use in surgical treatment of ankle fractures. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Issam El-Khaldi,Mads H Gude,Per H Gundtoft,Bjarke Viberg
Aims Pneumatic tourniquets are often used during the surgical treatment of unstable traumatic ankle fractures. The aim of this study was to assess the risk of reoperation after open reduction and internal fixation of ankle fractures with and without the use of pneumatic tourniquets. Methods This was a population-based cohort study using data from the Danish Fracture Database with a follow-up period
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The bone trauma and soft-tissue injury classification system in total hip arthroplasty (BOSTI Hip). Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Babar Kayani,Mohammed U K Wazir,Fabio Mancino,Ricci Plastow,Fares S Haddad
Aims The primary objective of this study was to develop a validated classification system for assessing iatrogenic bone trauma and soft-tissue injury during total hip arthroplasty (THA). The secondary objective was to compare macroscopic bone trauma and soft-tissues injury in conventional THA (CO THA) versus robotic arm-assisted THA (RO THA) using this classification system. Methods This study included
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The impact of a femoral stem collar on primary hip arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Babar Kayani,Kevin Staats,Fares S Haddad
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Infographic: Defining accurate terminology for post-injury weightbearing instructions. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Alex J Trompeter,Matt L Costa,
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The effect of intra-articular autologous protein solution on knee osteoarthritis symptoms. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Marla Ross,Yushy Zhou,Michael English,Paul Sharplin,Marc Hirner
Aims Knee osteoarthritis (OA) is characterized by a chronic inflammatory process involving multiple cytokine pathways, leading to articular cartilage degeneration. Intra-articular therapies using pharmaceutical or autologous anti-inflammatory factors offer potential non-surgical treatment options. Autologous protein solution (APS) is one such product that uses the patient's blood to produce a concentrate
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Auditing the microbiological quality of the air in operating theatres. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 William Whyte,Andrew M Thomas
The critical relationship between airborne microbiological contamination in an operating theatre and surgical site infection (SSI) is well known. The aim of this annotation is to explain the scientific basis of using settle plates to audit the quality of air, and to provide information about the practicalities of using them for the purposes of clinical audit. The microbiological quality of the air
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Increased early complications after total hip arthroplasty compared with hemiarthroplasty in older adults with a femoral neck fracture. Bone Joint J. (IF 4.9) Pub Date : 2024-09-01 Masaki Hatano,Yusuke Sasabuchi,Toshiaki Isogai,Hisatoshi Ishikura,Takeyuki Tanaka,Sakae Tanaka,Hideo Yasunaga
Aims The aim of this study was to compare the early postoperative mortality and morbidity in older patients with a fracture of the femoral neck, between those who underwent total hip arthroplasty (THA) and those who underwent hemiarthroplasty. Methods This nationwide, retrospective cohort study used data from the Japanese Diagnosis Procedure Combination database. We included older patients (aged ≥
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The cereblon-AMPK (AMP-activated protein kinase) axis in chondrocytes regulates the pathogenesis of osteoarthritis Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-08-30 Yeon Lee, Hyo-Eun Kim, Ji-Sun Kwak, Chul-Seung Park, Jang-Soo Chun
AMP-activated protein kinase (AMPK) dysregulation is implicated in osteoarthritis (OA), but the mechanisms underlying this dysregulation remain unclear. We investigated the role of cereblon, a substrate-recognition protein within the E3-ligase ubiquitin complex, in AMPK dysregulation and OA pathogenesis. Cereblon expression was examined in human (n = 5) and mouse (n = 10) OA cartilage. The role of