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Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect Bone Res. (IF 14.3) Pub Date : 2024-10-18 Bilal M. El-Masri, Christina M. Andreasen, Kaja S. Laursen, Viktoria B. Kofod, Xenia G. Dahl, Malene H. Nielsen, Jesper S. Thomsen, Annemarie Brüel, Mads S. Sørensen, Lars J. Hansen, Albert S. Kim, Victoria E. Taylor, Caitlyn Massarotti, Michelle M. McDonald, Xiaomeng You, Julia F. Charles, Jean-Marie Delaisse, Thomas L. Andersen
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Osteoarthritis Year in Review 2024: Molecular Biomarkers of Osteoarthritis. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-18 Hope D Welhaven,Avery H Welfley,Ronald K June
OBJECTIVE To provide a comprehensive and insightful summary of studies on molecular biomarkers at the gene, protein, and metabolite levels across different sample types and joints affected by osteoarthritis (OA). METHODS A literature search using the PubMed database for publications on OA biomarkers published between April 1, 2023 and April 30, 2024 was performed. Publications were then screened, examined
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Osteopetrosis-like disorders induced by osteoblast-specific retinoic acid signaling inhibition in mice Bone Res. (IF 14.3) Pub Date : 2024-10-17 Siyuan Sun, Yuanqi Liu, Jiping Sun, Bingxin Zan, Yiwen Cui, Anting Jin, Hongyuan Xu, Xiangru Huang, Yanfei Zhu, Yiling Yang, Xin Gao, Tingwei Lu, Xinyu Wang, Jingyi Liu, Li Mei, Lei Shen, Qinggang Dai, Lingyong Jiang
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Hierarchies in focus: crafting the gold standard for pain measures in knee osteoarthritis trials and meta-analyses. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-17 Robin Christensen,Carsten B Juhl
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SEX-SPECIFIC DIVERGENCES IN THE TYPES AND TIMING OF INFILTRAING IMMUNE CELL DURING THE INTERVERTEBRAL DISC ACUTE INJURY RESPONSE IS ASSOCIATED WITH REDUCED DEGENERATIVE CHANGES. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-17 Sade W Clayton,Remy E Walk,Laura Mpofu,Garrett W D Easson,Simon Y Tang
OBJECTIVE Inadequate repair of the intervertebral disc (IVD) contributes to low back pain. Infiltrating immune cells into damaged tissues are critical mediators of repair, yet little is known about the identities, roles, and temporal regulation following IVD injury. By analyzing transcripts of immune cell markers, histopathologic analysis, immunofluorescence, and flow cytometry, we aimed to define
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Dual-Mobility Articulations in Revision Total Hip Arthroplasty: A Comparison with Metal or Ceramic on Highly Cross-Linked Polyethylene and Constrained Articulations. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-17 Monti Khatod,Priscilla H Chan,Heather A Prentice,Brian H Fasig,Elizabeth W Paxton,Nithin C Reddy,Matthew P Kelly
BACKGROUND The increased availability of dual-mobility acetabular constructs (DMCs) provides surgeons with a newer option to increase the effective femoral head size in revision total hip arthroplasty (rTHA). We sought to evaluate risks of re-revision and prosthetic dislocation following rTHA involving a DMC compared with other articulations. METHODS A cohort study was conducted using data from a U
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To Provide Care, or to Care for?: The Influence of Language on Medicine. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-17 Anna L Park,Louise Aronson,Mohammad Diab
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A Computer Modeling-Based Target Zone for Transposition Osteotomy of the Acetabulum in Patients with Hip Dysplasia. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-17 Kenji Kitamura,Masanori Fujii,Goro Motomura,Satoshi Hamai,Shinya Kawahara,Taishi Sato,Ryosuke Yamaguchi,Daisuke Hara,Takeshi Utsunomiya,Yasuharu Nakashima
BACKGROUND This study aimed to determine the acetabular position to optimize hip biomechanics after transposition osteotomy of the acetabulum (TOA), a specific form of periacetabular osteotomy, in patients with hip dysplasia. METHODS We created patient-specific finite-element models of 46 patients with hip dysplasia to simulate 12 virtual TOA scenarios: lateral rotation to achieve a lateral center-edge
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A monoallelic variant in CCN2 causes an autosomal dominant spondyloepimetaphyseal dysplasia with low bone mass Bone Res. (IF 14.3) Pub Date : 2024-10-16 Shanshan Li, Rui Shao, Shufa Li, Jiao Zhao, Qi Deng, Ping Li, Zhanying Wei, Shuqin Xu, Lin Chen, Baojie Li, Weiguo Zou, Zhenlin Zhang
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Letter to the editor regarding "Association between synovial tissue damage and pain in late-stage knee osteoarthritis: A cross-sectional study". Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-16 Tzu Han Feng,Chen Dong,Brian Shiian Chen,James Cheng Chung Wei
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CORR Insights®: What Are the Relative Associations of Surgeon Performance and Prosthesis Quality With THA Revision Rates? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-10-16 Jashvant Poeran
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Versatility of 14-3-3 proteins and their roles in bone and joint-related diseases Bone Res. (IF 14.3) Pub Date : 2024-10-15 Renpeng Zhou, Weirong Hu, Peter X. Ma, Chuan-ju Liu
Bone and joint-related diseases, including osteoarthritis (OA), rheumatoid arthritis (RA), and bone tumors, pose significant health challenges due to their debilitating effects on the musculoskeletal system. 14-3-3 proteins, a family of conserved regulatory molecules, play a critical role in the pathology of these diseases. This review discusses the intricate structure and multifunctionality of 14-3-3
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Periostin+ myeloid cells improved long bone regeneration in a mechanosensitive manner Bone Res. (IF 14.3) Pub Date : 2024-10-15 Ziyan Wang, Minmin Lin, Yonghao Pan, Yang Liu, Chengyu Yang, Jianqun Wu, Yan Wang, Bingtong Yan, Jingjing Zhou, Rouxi Chen, Chao Liu
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Protein Folding Dependence on Selenoprotein M Contributes to Steady Cartilage Extracellular Matrix Repressing Ferroptosis Via PERK/ATF4/CHAC1 Axis. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-15 Yitong Zhao,Ying Zheng,Han Li,Yao Li,Ru Wang,Yongsong Cai,Haishi Zheng,Xinyu Huo,Jiajun Ren,Dongxian Guo,Rui Luo,Xinyao Wu,Jingyi Lu,Qingxin Song,Yan Zhang,Chenxing Ma,Lu Wang,Runyuan Wang,Jing Wang,Yingli He,Peng Xu,Jian Sun,Shemin Lu
OBJECTIVE Initiation of endoplasmic reticulum (ER) stress is pivotal to the advancement of osteoarthritis (OA). We aimed to explore the function of ER-resident selenoprotein M (SELM) in cartilage-forming chondrocytes, investigating how SELM participates in cartilage extracellular matrix (ECM) metabolism and ER stress modulation. METHODS Articular cartilage samples with knee OA undergoing total knee
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Metabolic reprogramming in skeletal cell differentiation Bone Res. (IF 14.3) Pub Date : 2024-10-11 Joshua C. Bertels, Guangxu He, Fanxin Long
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Is Kinesiophobia Associated With Quality of Life, Level of Physical Activity, and Function in Older Adults With Knee Osteoarthritis? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-10-09 Shaun Kai Kiat Chua,Chien Joo Lim,Yong Hao Pua,Su-Yin Yang,Bryan Yijia Tan
BACKGROUND Beyond knee pain itself, the fear of movement, also known as kinesiophobia, recently has been proposed as a potential factor contributing to disability and functional limitation in patients with knee osteoarthritis (OA). Nevertheless, the available evidence on the association of kinesiophobia with patient-reported outcome measures (PROMs) in knee OA remains limited. QUESTIONS/PURPOSES Among
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Radiographically Apparent Acetabular Sourcil Landmarks Are Created by Comparable Regions of the Pelvis With Extraarticular Bone Variably Confounding Estimates of Joint Coverage. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-10-09 Dominic J L Rivas,Stuart Weinstein,Marcus Tatum,Holly D Aitken,Alison Ford,Spencer Dempewolf,Michael C Willey,Jessica E Goetz
BACKGROUND The severity of hip dysplasia is characterized by radiographic measurements that require user definition of the acetabular sourcil edge, a bony landmark for which the corresponding three-dimensional (3D) anatomy is not well defined in any imaging plane. QUESTIONS/PURPOSES To use digitally reconstructed radiographs to determine: (1) What 3D anatomy is contributing to the "acetabular sourcil"
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Making sense of osteoarthritis: A narrative review. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-09 Ben Darlow,Joletta Belton,Melanie Brown,Jane Clark,Dawn P Richards,Naomi Simick Behera,Samantha Bunzli
People make sense of osteoarthritis (OA) by drawing on information, beliefs, and knowledge. This narrative review summarises diverse qualitative and quantitative research investigating beliefs and knowledge about OA and the impact these have on behaviour and outcomes. It synthesises evidence and highlights key actions clinicians can take to support people to make sense of OA in helpful ways. Beliefs
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Emerging evidence of artemin/GFRα3 signaling in musculoskeletal pain. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-05 Ankita Gupta,Santosh K Mishra,B Duncan X Lascelles
Chronic musculoskeletal pain is highly prevalent and poses a significant personal, societal, and economic burden. Management of chronic musculoskeletal pain remains a challenge. Long-term use of common analgesic medications such as nonsteroidal anti-inflammatory drugs and opioids is associated with adverse events, and in the case of opioids, drug addiction. Additionally, many individuals do not experience
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Osteoarthritis year in review 2024: Biomechanics. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-04 Annegret Mündermann,Corina Nüesch,Hannah Ewald,Ilse Jonkers
OBJECTIVE We aimed to systematically review and summarize the literature of the past year on osteoarthritis (OA) and biomechanics, to highlight gaps and challenges, and to present some promising approaches and developments. METHODS A systematic literature search was conducted using Pubmed and the Web of Science Core Collection. We included original articles and systematic reviews on OA and biomechanics
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Does a Concise Patient-reported Outcome Measure Provide a Valid Measure of Physical Function for Cancer Patients After Lower Extremity Surgery? Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-10-04 Theresa Nalty,Shalin S Patel,Justin E Bird,Valerae O Lewis,Patrick P Lin
BACKGROUND Current functional assessment tools for orthopaedic oncology are long surveys that contribute to patients' survey fatigue and yet lack the ability to discern meaningful differences in a patient population that is often mobile but unable to perform strenuous activities. We sought to determine whether a shorter, novel tool based on existing, validated surveys could better capture differences
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High-Dose TXA Is Associated with Less Blood Loss Than Low-Dose TXA without Increased Complications in Patients with Complex Adult Spinal Deformity. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-03 Andrew H Kim,Kevin C Mo,Andrew B Harris,Renaud Lafage,Brian J Neuman,Richard A Hostin,Alexandra Soroceanu,Han Jo Kim,Eric O Klineberg,Jeffrey L Gum,Munish C Gupta,D Kojo Hamilton,Frank Schwab,Doug Burton,Alan Daniels,Peter G Passias,Robert A Hart,Breton G Line,Christopher Ames,Virginie Lafage,Christopher I Shaffrey,Justin S Smith,Shay Bess,Lawrence Lenke,Khaled M Kebaish,
BACKGROUND Tranexamic acid (TXA) is commonly utilized to reduce blood loss in adult spinal deformity (ASD) surgery. Despite its widespread use, there is a lack of consensus regarding the optimal dosing regimen. The aim of this study was to assess differences in blood loss and complications between high, medium, and low-dose TXA regimens among patients undergoing surgery for complex ASD. METHODS A multicenter
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Validation of Examination Maneuvers for Adolescent Idiopathic Scoliosis in the Telehealth Setting. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-02 Alexander R Farid,M Timothy Hresko,Semhal Ghessese,Gabriel S Linden,Stephanie Wong,Daniel Hedequist,Craig Birch,Danielle Cook,Kelsey Mikayla Flowers,Grant D Hogue
BACKGROUND Telehealth visits (THVs) have made it essential to adopt innovative ways to evaluate patients virtually. This study validates a novel THV approach that uses educational videos and an instructional datasheet, enabling parents to use smartphones to measure their child's scoliosis at home or in telehealth settings. METHODS We identified a prospective cohort of patients with adolescent idiopathic
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AOA Critical Issues Symposium: The Disruptive Physician: Bad Apple or Toxic Tree? J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-10-02 Rey N Ramirez,Joel L Mayerson,Valerae O Lewis,Alan Friedman,Lisa Lattanza
Disruptive physician behavior has become a common problem in medicine. Individuals who conduct themselves in a manner that could negatively affect patient care, or "disruptive physicians," frequently cause stress for patients and staff, are a headache for leadership, and can require expensive remediation. We suggest that rather than "bad apples," many disruptive physicians are the fruit of a "toxic
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De Novo Natural Language Processing Algorithm Accurately Identifies Myxofibrosarcoma From Pathology Reports. Clin. Orthop. Relat. Res. (IF 4.2) Pub Date : 2024-10-02 Sarah E Lindsay,Cecelia J Madison,Duncan C Ramsey,Yee-Cheen Doung,Kenneth R Gundle
BACKGROUND Available codes in the ICD-10 do not accurately reflect soft tissue sarcoma diagnoses, and this can result in an underrepresentation of soft tissue sarcoma in databases. The National VA Database provides a unique opportunity for soft tissue sarcoma investigation because of the availability of all clinical results and pathology reports. In the setting of soft tissue sarcoma, natural language
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What if OA cartilage degradation is driven by the infrapatellar fat pad? Insights from lipodystrophy models. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-02 Lea Loisay,Xavier Houard
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Cartilage on the test bench - What is the functional role of synovial fluid in reducing wear and fatigue? Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-10-02 Markus A Wimmer,Thomas M Schmid
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Metabolic syndrome and patient-reported outcome two years after hip and knee arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Rasmus R Sørensen,Signe Timm,Lasse E Rasmussen,Claus L Brasen,Claus Varnum
Aims The influence of metabolic syndrome (MetS) on the outcome after hip and knee arthroplasty is debated. We aimed to investigate the change in patient-reported outcome measure (PROM) scores after hip and knee arthroplasty, comparing patients with and without MetS. Methods From 1 May 2017 to 30 November 2019, a prospective cohort of 2,586 patients undergoing elective unilateral hip and knee arthroplasty
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Ultrasound-guided infiltration with hyaluronic acid compared with corticosteroid for the treatment of Morton's neuroma. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Gabriel F Ferreira,Thomas L Lewis,Tifani D Fernandes,João P Pedroso,Gustavo G Arliani,Robbie Ray,Vitor A Patriarcha,Miguel V Filho
Aims A local injection may be used as an early option in the treatment of Morton's neuroma, and can be performed using various medications. The aim of this study was to compare the effects of injections of hyaluronic acid compared with corticosteroid in the treatment of this condition. Methods A total of 91 patients were assessed for this trial, of whom 45 were subsequently included and randomized
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The outcomes of surgical treatment of complex radial head fractures. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Tim Jakobi,Inke Krieg,Yves Gramlich,Matthias Sauter,Matthias Schnetz,Reinhard Hoffmann,Alexander Klug
Aims The aim of this study was to evaluate the outcome of complex radial head fractures at mid-term follow-up, and determine whether open reduction and internal fixation (ORIF) or radial head arthroplasty (RHA) should be recommended for surgical treatment. Methods Patients who underwent surgery for complex radial head fractures (Mason type III, ≥ three fragments) were divided into two groups (ORIF
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Staged revision of the infected knee arthroplasty and endoprosthesis. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Christopher J Lodge,Amirul Adlan,Rajpal S Nandra,Jasprit Kaur,Lee Jeys,Jonathan D Stevenson
Aims Periprosthetic joint infection (PJI) is a challenging complication of any arthroplasty procedure. We reviewed our use of static antibiotic-loaded cement spacers (ABLCSs) for staged management of PJI where segmental bone loss, ligamentous instability, or soft-tissue defects necessitate a static construct. We reviewed factors contributing to their failure and techniques to avoid these complications
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The effect of combined malnutrition and obesity on trauma and orthopaedic surgery outcomes. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Diego A Abelleyra Lastoria,Chigoziem Ogbolu,Olufemi Olatigbe,Rebecca Beni,Ahsan Iftikhar,Caroline B Hing
Aims To determine whether obesity and malnutrition have a synergistic effect on outcomes from skeletal trauma or elective orthopaedic surgery. Methods Electronic databases including MEDLINE, Global Health, Embase, Web of Science, ScienceDirect, and PEDRo were searched up to 14 April 2024, as well as conference proceedings and the reference lists of included studies. Studies were appraised using tools
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A focus on the Shoulder and Elbow in 2024. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 T Duncan Tennent,Adam C Watts,Fares S Haddad
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Preoperative patient-reported outcome measures predict minimal clinically important difference and patient-acceptable symptomatic state following arthroscopic Bankart repair. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Yi Long,Zhen-Ze Zheng,Xin-Hao Li,De-Dong Cui,Xing-Hao Deng,Jiang Guo,Rui Yang
Aims The aims of this study were to validate the minimal clinically important difference (MCID) and patient-acceptable symptom state (PASS) thresholds for Western Ontario Shoulder Instability Index (WOSI), Rowe score, American Shoulder and Elbow Surgeons (ASES), and visual analogue scale (VAS) scores following arthroscopic Bankart repair, and to identify preoperative threshold values of these scores
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Characterization of articular lesions associated with glenohumeral instability using arthroscopy. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Gonzalo Luengo-Alonso,Maria Valencia,Natalia Martinez-Catalan,Cristina Delgado,Emilio Calvo
Aims The prevalence of osteoarthritis (OA) associated with instability of the shoulder ranges between 4% and 60%. Articular cartilage is, however, routinely assessed in these patients using radiographs or scans (2D or 3D), with little opportunity to record early signs of cartilage damage. The aim of this study was to assess the prevalence and localization of chondral lesions and synovial damage in
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Association between surgeon and hospital volume and outcome of first-time revision hip arthroplasty for aseptic loosening. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Richard J Holleyman,Simon S Jameson,R M Dominic Meek,Vikas Khanduja,Mike R Reed,Andrew Judge,Tim N Board
Aims This study evaluates the association between consultant and hospital volume and the risk of re-revision and 90-day mortality following first-time revision of primary hip arthroplasty for aseptic loosening. Methods We conducted a cohort study of first-time, single-stage revision hip arthroplasties (RHAs) performed for aseptic loosening and recorded in the National Joint Registry (NJR) data for
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The management of idiopathic toe walking. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Yael Gelfer,Anne E McNee,Jennifer D Harris,Jason Mavrotas,Laura Deriu,John Cashman,Jonathan Wright,Alpesh Kothari,,,Mia Dunkley,Christine Douglas,Derfel Williams,Sarah Dewhurst,Amanda Trees
Aims The aim of this study was to gain a consensus for best practice of the assessment and management of children with idiopathic toe walking (ITW) in order to provide a benchmark for practitioners and guide the best consistent care. Methods An established Delphi approach with predetermined steps and degree of agreement based on a standardized protocol was used to determine consensus. The steering
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Factors associated with the choice of treatment for coronoid fractures. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Huub H de Klerk,Lukas P E Verweij,Job N Doornberg,Ruurd L Jaarsma,Tsuyoshi Murase,Neal C Chen,Michel P J van den Bekerom,,,Kekatpure Al,Bhashyam Ar,Watts Ac,van T A,Alder-Price Ac,Turow A,Boonrod A,Masri B,The B,Jadav B,Mudgal Cs,Lameijer Cm,Langhammer Cg,Tu Cg,Rosso C,Ring D,Ruch Ds,Eygendaal D,Alentorn-Geli E,Kholinne E,Ek Et,Bain Gi,Lawton Jn,White Ja,Phadnis J,Alexander J,Sato K,Shimada K,Boerboom
Aims This study aimed to gather insights from elbow experts using the Delphi method to evaluate the influence of patient characteristics and fracture morphology on the choice between operative and nonoperative treatment for coronoid fractures. Methods A three-round electronic (e-)modified Delphi survey study was performed between March and December 2023. A total of 55 elbow surgeons from Asia, Australia
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The impact of closed suction wound drainage on chronic pain and health-related quality of life after posterior spinal fusion in patients with adolescent idiopathic scoliosis. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Linda Helenius,Paul Gerdhem,Matti Ahonen,Johanna Syvänen,Jenni Jalkanen,Yrjänä Nietosvaara,Ilkka Helenius
Aims Closed suction subfascial drainage is widely used after instrumented posterior spinal fusion in patients with a spinal deformity. The aim of this study was to determine the effect of this wound drainage on the outcomes in patients with adolescent idiopathic scoliosis (AIS). This was a further analysis of a randomized, multicentre clinical trial reporting on patients after posterior spinal fusion
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Estimation of two-year hospital costs of hip and knee periprosthetic joint infection treatments using activity-based costing. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Aaron S Hammat,Renjy Nelson,Joshua S Davis,Laurens Manning,David Campbell,Lucian B Solomon,Emmanuel S Gnanamanickam,Stuart A Callary
Aims Our aim was to estimate the total costs of all hospitalizations for treating periprosthetic joint infection (PJI) by main management strategy within 24 months post-diagnosis using activity-based costing. Additionally, we investigated the influence of individual PJI treatment pathways on hospital costs within the first 24 months. Methods Using admission and procedure data from a prospective observational
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Glenohumeral joint kinematics during apprehension-relocation test in patients with anterior shoulder instability and glenoid bone loss. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Josephine Olsen Kipp,Emil T Petersen,Thomas Falstie-Jensen,Johanne Frost Teilmann,Anna Zejden,Rikke Jellesen Åberg,Sepp de Raedt,Theis M Thillemann,Maiken Stilling
Aims This study aimed to quantify the shoulder kinematics during an apprehension-relocation test in patients with anterior shoulder instability (ASI) and glenoid bone loss using the radiostereometric analysis (RSA) method. Kinematics were compared with the patient's contralateral healthy shoulder. Methods A total of 20 patients with ASI and > 10% glenoid bone loss and a healthy contralateral shoulder
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The impact of ethnicity on care and outcome after hip fracture in England and Wales. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Sohail Nisar,Jonathan Lamb,Antony Johansen,Robert West,Hemant Pandit
Aims To determine if patient ethnicity among patients with a hip fracture influences the type of fracture, surgical care, and outcome. Methods This was an observational cohort study using a linked dataset combining data from the National Hip Fracture Database and Hospital Episode Statistics in England and Wales. Patients' odds of dying at one year were modelled using logistic regression with adjustment
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Are the current minimal clinically important differences fit for purpose? Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Nick D Clement,Fares S Haddad
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Outcomes of arthroscopic stabilization for recurrent instability are equal to stabilization after a primary event. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Jawaad Saleem,Ben Rawi,Magnus Arnander,Eyiyemi Pearse,Duncan Tennent
Aims Extensive literature exists relating to the management of shoulder instability, with a more recent focus on glenoid and humeral bone loss. However, the optimal timing for surgery following a dislocation remains unclear. There is concern that recurrent dislocations may worsen subsequent surgical outcomes, with some advocating stabilization after the first dislocation. The aim of this study was
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Elbow kinematics with increased lengthening of a radial head arthroplasty evaluated with dynamic radiostereometric analysis. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Johanne Frost Teilmann,Emil T Petersen,Theis M Thillemann,Chalotte K Hemmingsen,Josephine Olsen Kipp,Thomas Falstie-Jensen,Maiken Stilling
Aims The aim of this study was to evaluate the kinematics of the elbow following increasing length of the radius with implantation of radial head arthroplasties (RHAs) using dynamic radiostereometry (dRSA). Methods Eight human donor arms were examined by dRSA during motor-controlled flexion and extension of the elbow with the forearm in an unloaded neutral position, and in pronation and supination
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Management of bone loss in anterior shoulder instability. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Antonio Arenas-Miquelez,Raul Barco,Francisco J Cabo Cabo,Abdul-Ilah Hachem
Bone defects are frequently observed in anterior shoulder instability. Over the last decade, knowledge of the association of bone loss with increased failure rates of soft-tissue repair has shifted the surgical management of chronic shoulder instability. On the glenoid side, there is no controversy about the critical glenoid bone loss being 20%. However, poor outcomes have been described even with
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Predicting recurrence of instability after a primary traumatic anterior shoulder dislocation. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Navnit S Makaram,Hannes Becher,Erlend Oag,Nicholas R Heinz,Conor J McCann,Samuel P Mackenzie,C M Robinson
Aims The risk factors for recurrent instability (RI) following a primary traumatic anterior shoulder dislocation (PTASD) remain unclear. In this study, we aimed to determine the rate of RI in a large cohort of patients managed nonoperatively after PTASD and to develop a clinical prediction model. Methods A total of 1,293 patients with PTASD managed nonoperatively were identified from a trauma database
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Pre- and postoperative Coronal Plane Alignment of the Knee classification and its impact on clinical outcomes in total knee arthroplasty. Bone Joint J. (IF 4.9) Pub Date : 2024-10-01 Toshiki Konishi,Satoshi Hamai,Hidetoshi Tsushima,Shinya Kawahara,Yukio Akasaki,Satoshi Yamate,Shuhei Ayukawa,Yasuharu Nakashima
Aims The Coronal Plane Alignment of the Knee (CPAK) classification has been developed to predict individual variations in inherent knee alignment. The impact of preoperative and postoperative CPAK classification phenotype on the postoperative clinical outcomes of total knee arthroplasty (TKA) remains elusive. This study aimed to examine the effect of postoperative CPAK classification phenotypes (I
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Assessment of whole cartilage surface damage in an osteoarthritis rat model: The Cartilage Roughness Score (CRS) utilizing microcomputed tomography. Osteoarthr. Cartil. (IF 7.2) Pub Date : 2024-09-30 Sami Kauppinen,David Fercher,Gonçalo Barreto,Ville-Pauli Karjalainen,Vesa Virtanen,Lucia Baixauli-Marin,Marina Fonti,Shipin Zhang,Tuomas Frondelius,Patrick Weber,Simo Saarakkala,Marcy Zenobi-Wong,Mikko A J Finnilä
OBJECTIVE This study aims to establish an accurate and robust imaging biomarker for pre-clinical osteoarthritis (OA) research, focusing on early detection of cartilage surface degeneration. METHOD Using 50 male Wistar rats, this study aims to observe Collagenase-induced OA (CIOA) progression through microcomputed x-ray tomography (µCT), histopathological analysis, and gait analysis. A novel parameter
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Delayed Unions or Nonunions of the Distal Femur: A Comprehensive Overview. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-30 Elsa B Rodriguez-Baron,Hosaam Gawad,Basem Attum,William T Obremskey
➢ The failure rate of treatment of nonunions of the distal femur with internal fixation and autologous bone grafting remains high at 20% to 30%.➢ Successful treatment of nonunions of the distal femur requires good mechanical stability combined with autologous bone graft. This may require dual-plate fixation or intramedullary nail-plate combinations.➢ Autologous bone graft remains the bone graft of
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Multimodal analyses of immune cells during bone repair identify macrophages as a therapeutic target in musculoskeletal trauma Bone Res. (IF 14.3) Pub Date : 2024-09-29 Yasmine Hachemi, Simon Perrin, Maria Ethel, Anais Julien, Julia Vettese, Blandine Geisler, Christian Göritz, Céline Colnot
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Spatial multiplexed immunofluorescence analysis reveals coordinated cellular networks associated with overall survival in metastatic osteosarcoma Bone Res. (IF 14.3) Pub Date : 2024-09-27 Ryan A. Lacinski, Sebastian A. Dziadowicz, Vincent K. Melemai, Brody Fitzpatrick, John J. Pisquiy, Tanya Heim, Ines Lohse, Karen E. Schoedel, Nicolas J. Llosa, Kurt R. Weiss, Brock A. Lindsey
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What's Important: Moving Orthopaedic Patient Care Forward: Tips for Successful Systems Improvement. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-27 David N Bernstein,Robert Kaspar Wagner,Jacob S Borgida,Mitchel B Harris,Thuan V Ly
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No Discernible Difference in Revision Rate or Survivorship Between Posterior Cruciate-Retaining and Posterior Cruciate-Substituting TKA. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-27 Young-Hoo Kim,Jang-Won Park,Young-Soo Jang,Eun-Jung Kim
BACKGROUND Many authors and the data of multiple registries have suggested that the use of posterior cruciate-substituting (posterior stabilized [PS]) total knee arthroplasty (TKA) leads to a higher risk of revision compared with the use of posterior cruciate-retaining (CR) TKA. The aim of the present prospective, randomized, long-term study was to compare PS and CR TKA with regard to the clinical
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Pharmacologic or genetic targeting of peripheral nerves prevents peri-articular traumatic heterotopic ossification Bone Res. (IF 14.3) Pub Date : 2024-09-26 Manyu Zhu, Ji-Hye Yea, Zhao Li, Qizhi Qin, Mingxin Xu, Xin Xing, Stefano Negri, Mary Archer, Monisha Mittal, Benjamin Levi, Aaron W. James
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Short-Term Complications of Arthroscopic Bristow or Latarjet Procedure with Screw Versus Suture-Button Fixation: A Prospective Study of 308 Consecutive Cases by a Single Surgeon. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-26 Zhenxing Shao,Yanfang Jiang,Qingfa Song,Hangle Wang,Hao Luo,Xu Cheng,Guoqing Cui
BACKGROUND This study aimed to investigate the short-term complications (minimum 1-year follow-up) after either an arthroscopic Bristow or Latarjet procedure for anterior shoulder instability utilizing screw or suture-button fixation. METHODS Patients undergoing arthroscopic Bristow or Latarjet procedures between November 2016 and April 2021 were enrolled. Data were collected at baseline, 3 months
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Do Half of Orthopaedic Surgeons Change Jobs within Their First 2 Years?: An Analysis Using the American Board of Orthopaedic Surgery Database. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-26 Jonathan D McKeeman,Dustin A Greenhill,Akhil Sharma,John J Harrast,David F Martin,Douglas W Lundy
BACKGROUND The claim that "50% of orthopaedic surgeons leave their first job within 2 years" did not originate from evidence. The purpose of this study was to investigate practice change rates among board- eligible orthopaedic surgeons using the American Board of Orthopaedic Surgery (ABOS) database. METHODS We utilized information provided by orthopaedic surgeons taking the ABOS Part II Examination
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What's Important: Breaking Bread Together, Finding an Extracurricular Pursuit. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-26 Stephen P Maier
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Sagittal Fragment Rotation and Ogden Type-I Classification Are Hallmarks of Combined Tibial Tubercle Fracture and Patellar Tendon Injury. J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-26 Rebecca J Schultz,Jason Z Amaral,Matthew J Parham,Raymond L Kitziger,Tiffany M Lee,Scott D McKay,Basel M Touban
BACKGROUND Tibial tubercle fractures (TTFs) are uncommon injuries, comprising <3% of all proximal tibial fractures. These fractures occasionally occur in conjunction with a patellar tendon injury (PTI). We aimed to identify risk factors associated with combined TTF and PTI. METHODS A retrospective review was performed of patients presenting to a single, tertiary children's hospital with TTF between
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Review of the Influences of Sex Differences on Health and Disease: What Is the Role of Journals? J. Bone Joint. Surg. (IF 4.4) Pub Date : 2024-09-26 Judith G Regensteiner,Kimberly Templeton
➢ Sex-based differences are understudied, which has potential consequences for the health of everyone.➢ Women's health is particularly affected given a lack of sex-specific data across many disease states.➢ Journals do not consistently require the inclusion of both sexes and the disaggregation of data by sex in cell, animal model, and human studies.➢ Instructions for investigators and journals regarding