The objective of the study was to assess the effect of soft-tissue volume augmentation during early, delayed, and late dental implant therapy in terms of professionally determined esthetics and self-reported patient satisfaction on esthetics. For this, a comprehensive electronic literature search was performed to identify randomized clinical trials (RCTs) and controlled clinical trials (CCTs) reporting

Background and AimManaging periodontal disease often involves complex decisions involving multiple treatment options, and patient autonomy significantly influences this decision‐making process. This study aimed to characterise the autonomy and information‐seeking preferences among patients diagnosed with stage III/IV periodontitis, and to identify the factors influencing these preferences.Materials

AimTo evaluate the impact of macrophage depletion on bone loss and inflammatory responses in a mouse model of peri‐implantitis, assessing macrophage depletion potential as a therapeutic strategy.Materials and MethodsUsing 6‐week‐old male C57BL/6 mice, peri‐implantitis was induced by placing a silk ligature around osteointegrated dental implants. Mice were divided into three groups: Healthy control

AimTo evaluate early buccal bone resorption (BBR) in areas with or without buccal keratinized tissue (KT), and different mucosal thickness (MT) following implant placement at healed sites.Materials and MethodsIn 9 beagle dogs, three months following the hemimaxilla third and fourth premolars extraction, full‐thickness flaps were elevated and two tissue‐level implants were inserted. Before suturing

AimsTo quantify changes in soft‐tissue volume induced by non‐surgical periodontal therapy (NSPT) in patients with periodontitis and correlate them with clinical parameters and smoking. A new digital approach is investigated because standard periodontal clinical assessment methods are unable to accurately capture volumetric changes.Materials and MethodsThirty‐nine subjects with periodontitis aged 27–70

BackgroundBisphosphonates (BPs) are effective in managing bone diseases due to their anti‐resorptive properties but are linked to medication‐related osteonecrosis of the jaw (MRONJ), particularly concerning dental implants. This study explored the combined impact of ligature‐induced peri‐implant inflammation and zoledronic acid (ZA), a BP, using a murine model.MethodsTwenty‐four mice underwent bilateral

BackgroundAccurately replicating the emergence profile (EP) of conditioned soft tissue is pivotal for the success of implant‐supported restorations. In the field of digital technology, various methods have emerged to capture EP. This review aims to critically assess current digital methodologies for capturing peri‐implant EP.Material and MethodsProspective interventional or observational clinical studies

AimTo assess the efficacy of injectable bone fillers for alveolar ridge preservation (ARP).Materials and MethodsThe mandibular premolars (P2, P3, P4) were bilaterally assigned to ARP in a total of n = 9 beagle dogs. Each P was decapitated and hemisected under preservation of the mesial (i.e., devitalization and filling with calcium hydroxide) and removal of the distal root. The resulting 6 extraction

BackgroundThe widespread adoption of digital technologies in dentistry has transformed workflows and practices. However, limited, if any, information is available on the extent of digital workflow integration in periodontics. This study aims to evaluate literacy, utilization, and knowledge of digital technologies, specifically implant navigation systems, among American board‐certified periodontists

BackgroundThe aim of this study was to evaluate the effect of surgical guide design and type of blade, in relation to soft tissue thickness, on the accuracy of computer‐assisted crown lengthening.MethodsA set of fully dentate anatomic maxilla models was implemented, using 2 types of soft‐tissue masks with a mean thickness of 1.5 and 3.5 mm, respectively, to simulate a clinical scenario of altered passive

AimTo evaluate a deep learning (DL) model for detecting keratinized gingiva (KG) in dental photographs and validate its clinical applicability using reference retainers for calibration.Materials and MethodsA total of 576 sextant photographs were selected from 32 subjects, each with three sets of photographs: iodine‐stained, unstained and line‐marked retainers. Relative keratinized gingiva width (rKGW)

AimsTo identify genetic biomarkers that may be used in the diagnosis, prevention or management of different forms of periodontal disease.Materials and MethodsFollowing protocol registration and PICOTS (patient, intervention, comparison, outcome, time, studies) questions, a systematic search of the literature was conducted (PudMed, Ovid), resulting in 1592 papers screened by two reviewers. Diagnostic

AimTo assess the medium‐term implant success and survival rates of immediately placed and restored implants with a novel design in the esthetic zone.Materials and MethodsA total of n = 20 patients had received immediately placed tapered, two‐part implants with a progressive thread design (PL) (n = 20) and an immediate “non full‐functional” loading (patient‐specific abutments) for single tooth replacements

ObjectivesThe aim of this scoping review is to determine the effects of autoimmune diseases (ADs) and the agents used for treatment on dental implant survival and biologic outcomes.Material and MethodsAn electronic database search was performed in MEDLINE (PubMed), The Cochrane Library, and Embase on 29‐04‐2024. Clinical studies in English on implant therapy in patients with ADs were potentially eligible

Antiseptics such as chlorhexidine digluconate (CHX) are widely used in clinical dental practice, but their potential risks, particularly regarding antimicrobial resistance (AMR), are not yet known. This study explores the genomic and transcriptomic mechanisms of CHX adaptation in 3 clinical isolates of Streptococcus spp. and their adapted counterparts. The genomic analysis revealed mutations in genes

ObjectivesThis study evaluated the image quality of smartglass‐supported Dynamic Computer‐Assisted Implant Surgery (dCAIS) by testing discernibility with a Landolt ring chart reproduced with smartglasses and on the dCAIS monitor.Materials and Methods15 participants’ discernibility was measured under four conditions using Landolt rings. Each condition measured 13 visual acuity levels, with each level

BackgroundPeriodontitis is a destructive disease that affects periodontal tissue. While current research focuses on disease management, research on tissue repair remains limited. Metformin, a first‐line medication for diabetes treatment, has positive effects on bone health in nondiabetic patients. However, its potential for repairing periodontal tissue remains unclear. Therefore, this study aimed to

BackgroundCollagenated bovine bone mineral (CBBM) is used for maxillary sinus elevation‐based augmentation. We compared collagen degradation in cross‐linked (CL) CBBM and non‐cross‐linked (NCL) CBBM (in vitro) and preclinical results in CBBM‐CL, CBBM‐NCL, deproteinized bovine bone mineral (DBBM), and DBBM with fibrin sealant grafts (in vivo) after repair of perforated Schneiderian membrane (SM).Me

AimsTo evaluate the impact of an anti‐sensitivity toothpaste on the oral‐health‐related quality of life (OHrQoL) in a real‐world (RW) setting.Materials and MethodsThis was a decentralised, prospective, 24‐week, open‐label study in participants with self‐reported dentine hypersensitivity (DH). A total of 655 enrolled participants used a 5% potassium nitrate toothpaste per label instructions and completed

BackgroundPeri‐implantitis has become an important health issue in implant dentistry in the past years. Despite the magnitude of this problem and the potential grave consequences, the predictability and long‐term stability of its treatment is still a matter of controversy. The aim of this study was to assess clinical and radiographic results 5 years after the peri‐implantitis reconstructive treatment

BackgroundChronic rhinosinusitis (CRS) and chronic periodontitis (CP) are prevalent inflammatory conditions with significant impacts on health. Previous research has suggested a potential link between these diseases, primarily through odontogenic sources, but comprehensive population‐based studies are scarce. This study aimed to explore the association of CRS with prior CP.MethodsWe performed a case‐control

BackgroundThe purpose of this randomized, three‐armed clinical trial is to determine if a postoperative injection of 0.5% bupivacaine is more effective than 2% lidocaine in controlling pain after periodontal flap surgery.MethodsSeventy‐six patients planned for similar periodontal surgeries were included. Prior to surgery, patients were randomized to receive one cartridge (1.7 mL) of either 2% lidocaine

BackgroundPeriodontitis is a chronic inflammatory condition that affects the supporting structures of the teeth. It is closely associated with oxidative stress and inflammation. Taurine, a semi‐essential amino acid recognized for its antioxidant and anti‐inflammatory properties, has not been extensively investigated in the context of periodontitis. This pilot study sought to evaluate the levels of

The cover image is based on the article Impact of Collagen Membrane in Vertical Ridge Augmentation Using Ti‐Reinforced PTFE Mesh: A Randomised Controlled Trial by Istvan A. Urban et al., https://doi.org/10.1111/jcpe.14129. image

ObjectivesTo assess the reproduction accuracy of a surgical guide during both the manufacturing phase (from designed files to manufactured surgical guides) and the application phase (from manufactured surgical guides to post‐plasma sterilization) across four three‐dimensional (3D) printing technologies.Materials and MethodsTwenty‐four surgical guides were designed and categorized into four groups (six

ObjectivesThis study evaluated the effectiveness of force‐feedback–based autonomous dental implant robotic systems combined with osseodensification (OD) for transcrestal sinus floor elevation (TSFE), to understand patterns of force‐feedback curves, visualize the TSFE process through mechanical vision, and offer new perspectives on surgical strategies.Materials and MethodsThe included patients required

ObjectiveThis randomised clinical trial aimed to compare the effects of multimedia information and verbal explanations on patients' knowledge and anxiety as primary outcomes and decision‐making as a secondary outcome.Materials and MethodsOne hundred patients needing dental replacement were randomly assigned (1:1) to either a multimedia group (n = 50) or a verbal group (n = 50). They completed self‐administered

The aim of this comprehensive review was to evaluate comparative studies on horizontal and fixed‐angle centrifugation methods for preparing platelet‐rich fibrin (PRF). Furthermore, additional studies utilizing horizontal PRF (H‐PRF) were systematically investigated. This overview review article offers deeper insights into the advantages of H‐PRF when compared to fixed‐angle methods across a wide range

Regenerating the functional dentin–pulp complex remains a significant challenge in endodontics. Conventional regenerative endodontic therapies often result in the formation of non–pulp-like tissue due to the uncontrolled induction of stem cells and cytokines. Mimicking developmental processes to promote regeneration represents a promising yet challenging approach in regenerative medicine. This study

Extracellular vesicles (EVs) are lipid-enclosed particles released from cells, containing lipids, DNA, RNA, metabolites, and cytosolic and cell surface proteins. EVs support intercellular communication and orchestrate organogenesis by transferring bioactive molecules in between cells. Mesenchymal stem cells are known to produce EVs, which exhibit immunomodulatory and regenerative capabilities in many

This systematic review aimed to evaluate all available evidence across all fields of medicine regarding the comparative effectiveness of platelet‐rich plasma (PRP) versus injectable platelet‐rich fibrin (i‐PRF). A comprehensive search was conducted in PubMed, Scopus, and Web of Science up to September 30, 2024. Following a thorough screening process, studies were divided into in vitro, in vivo, and

BackgroundPeri‐implantitis is an oral inflammatory disease with increased incidence across the population as linked to the wide use of dental implants to replace missing teeth. While the recent World Workshop Classifications provided a framework for clinicians to diagnose and assess the severity of peri‐implantitis, an objective assessment of the mucosal inflammatory burden around the dental implant

BackgroundPeri‐implantitis poses a major challenge as contemporary nonsurgical treatments show dissatisfactory results and mucosal flap surgery is often needed. Diode lasers can remove granulation tissue and submucosal bacteria, and if it achieves similar clinical results, then it could be used as a less invasive first approach. The aim was to compare the healing of peri‐implantitis lesions 6 months

AimTo evaluate the clinical, microbial and cytokine changes following the use of oral azithromycin as an adjunct to non‐surgical subgingival instrumentation (NSI) in stage III/IV, grade C periodontitis through a triple‐blind, parallel‐armed, randomised controlled trial.Material and MethodsA total of 52 patients with stage III/IV grade C periodontitis were randomly allocated to two groups receiving

AimTo compare the dimensional outcomes of horizontal augmentation with the retentive‐flap technique using particulate and cross‐linked collagenated bone substitutes.Materials and MethodsThis two‐centre, two‐arm randomized clinical trial investigated 69 subjects: 34 in the particulate group and 35 in the collagenated group. Patients were randomly assigned to receive single implant placement with simultaneous

ObjectivesTo systematically appraise the evidence on premature ridge resorption following various vertical ridge augmentation (VRA) techniques in healthy adult patients undergoing staged VRA procedures. The study aimed to identify VRA techniques resulting in the least premature bone resorption and to rank them using Bayesian Network Meta‐Analysis (NMA).Material and MethodsSearches were conducted in