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Synergistic effects of using sodium hypochlorite (bleach) and desiccation in surface inactivation for Toxocara spp
Experimental Parasitology ( IF 2.1 ) Pub Date : 2024-04-15 , DOI: 10.1016/j.exppara.2024.108753
Janice L. Liotta , Alexandra Helfer , Lucy Huang , Timothy Wu , Dwight D. Bowman , Carlo Castillo , Hussni O. Mohammed , Bryant S. Blank

and are parasitic nematodes found in the intestines of cats and dogs respectively, with a cosmopolitan distribution, and the potential for anthropozoonotic transmission, resulting in human toxocariasis. Spread of spp. is primarily through the ingestion of embryonated eggs contaminating surfaces or uncooked food, or through the ingestion of a paratenic host containing a third-stage larva. The spp. eggshell is composed of a lipid layer providing a permeability barrier, a chitinous layer providing structural strength, and thin vitelline and uterine layers, which combined create a biologically resistant structure, making the spp. egg very hardy, and capable of surviving for years in the natural environment. The use of sodium hypochlorite, household bleach, as a disinfectant for spp. eggs has been reported, with results varying from ineffective to limited effectiveness depending on parameters including contact time, concentration, and temperature. Desiccation or humidity levels have also been reported to have an impact on larval development and/or survival of spp. eggs. However, to date, after a thorough search of the literature, no relevant publications have been found that evaluated the use of sodium hypochlorite and desiccation in combination. These experiments aim to assess the effects of using a combination of desiccation and 10% bleach solution (0.6% sodium hypochlorite) on fertilized or embryonated eggs of . and . Results of these experiments highlight the synergistic effects of desiccation and bleach, and demonstrate a relatively simple method for surface inactivation, resulting in a decrease in viability or destruction of , and eggs. Implications for these findings may apply to larger scale elimination of ascarid eggs from both research, veterinary, and farming facilities to mitigate transmission.

中文翻译:

使用次氯酸钠(漂白剂)和干燥对弓蛔虫属表面灭活的协同作用

和 是分别在猫和狗肠道中发现的寄生线虫,具有世界性分布,并且具有人畜共患传播的潜力,导致人类弓蛔虫病。物种的传播。主要是通过摄入污染表面或未煮熟的食物的含胚卵,或通过摄入含有第三阶段幼虫的寄生虫宿主。该种。蛋壳由提供渗透性屏障的脂质层、提供结构强度的几丁质层以及薄卵黄层和子宫层组成,这些层结合在一起形成了生物抵抗结构,使蛋壳成为一种生物抗性结构。鸡蛋非常耐寒,能够在自然环境中生存多年。使用次氯酸钠(家用漂白剂)作为细菌的消毒剂。据报道,鸡蛋的效果从无效到有限,具体取决于接触时间、浓度和温度等参数。据报道,干燥或湿度水平也会影响幼虫的发育和/或幼虫的存活。蛋。然而,迄今为止,经过彻底检索文献,尚未发现相关出版物评价次氯酸钠与干燥的联合使用。这些实验旨在评估结合使用干燥和 10% 漂白剂溶液(0.6% 次氯酸钠)对受精卵或含胚卵的影响。和 。这些实验的结果强调了干燥和漂白的协同效应,并证明了一种相对简单的表面失活方法,导致 和 鸡蛋的活力下降或破坏。这些发现的意义可能适用于从研究、兽医和农业设施中大规模消除蛔虫卵,以减少传播。
更新日期:2024-04-15
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