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Quantitative determination of selected elements in infant baby formulae and baby food cereals commercially available in Serbia using the ICP OES method J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-27 Emilija Pecev-Marinković, Ivana Rašić Mišić, Jelena Mrmošanin, Stefan Petrović, Aleksandra Pavlović, Snežana Tošić
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Boric acid alleviates periodontal inflammation induced by IL-1β in human gingival fibroblasts J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-26 Serife Buket Bozkurt, Sema S. Hakki, Forrest H. Nielsen
Boric acid (BA) has been found to have therapeutic effects on periodontal disease through beneficially affecting antibacterial, anti-viral, and anti-inflammatory actions. This study was conducted to determine the effect of BA on cell viability and on mRNA expressions of proinflammatory and anti-inflammatory cytokines and on oxidative stress enzymes induced by IL-1β (1 ng/mL) in Human Gingival Fibroblasts
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Titanium corrosion products from dental implants and their effect on cells and cytokine release: A review J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-24 Eswar Kandaswamy, M. Harsha, Vinayak M. Joshi
Titanium is considered to be an inert material owing to the ability of the material to form a passive titanium oxide layer. However, once the titanium oxide layer is lost, it can lead to exposure of the underlying titanium substructure and can undergo corrosion. The article explores the role of titanium ions and particles from dental implants on cells, cytokine release, and on the systemic redistribution
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Fostering healthy aging through selective nutrition: A long-term comparison of two dietary patterns and their holistic impact on mineral status in middle-aged individuals—A randomized controlled intervention trial in Germany J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-22 Denny Pellowski, Tom Heinze, Max Tuchtenhagen, Sandra M. Müller, Sören Meyer, Maria Maares, Christiana Gerbracht, Charlotte Wernicke, Hajo Haase, Anna P. Kipp, Tilman Grune, Andreas F.H. Pfeiffer, Knut Mai, Tanja Schwerdtle
Aging is associated with a decline in physiological functions and an increased risk of age-related diseases, emphasizing the importance of identifying dietary strategies for healthy aging. Minerals play a crucial role in maintaining optimal health during aging, making them relevant targets for investigation. Therefore, we aimed to analyze the effect of different dietary pattern on mineral status in
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The effects of cadmium on selected oxidative stress parameters and the content of photosynthetic pigments in cucumber Cucumis sativus L. J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-21 Agnieszka Rombel-Bryzek, Bartosz Bojarski, Paweł Świsłowski, Mateusz Jakubiak, Iryna Boliukh, Małgorzata Rajfur
Environmental pollution by cadmium (Cd) is currently a common problem in many countries, especially in highly industrialised areas. Cd present in the soil can be absorbed by plants through the root system. The aim of the present study was to investigate the effects of cadmium on the metabolic activity of cucumber plants ( L.) and the accumulation and distribution of Cd in the organs of the plants.
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Is chromium(III) pharmacologically relevant? An update focused on studies with diabetic rodent models J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-20 John B. Vincent
A decade ago, the author assessed the status of chromium as the trivalent ion as an essential element and as a therapeutic agent based on rodent studies for this journal. The current review was undertaken to update considerations regarding the status of chromium, focusing on studies of Cr supplementation of diabetic rodent models over the last decade. Cr can no longer be considered an essential trace
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Interaction and competition for intestinal absorption by zinc, iron, copper, and manganese at the intestinal mucus layer J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-17 Vincent Einhorn, Hajo Haase, Maria Maares
Trace elements such as zinc, manganese, copper, or iron are essential for a wide range of physiological functions. It is therefore crucial to ensure an adequate supply of these elements to the body. Many previous investigations have dealt with the role of transport proteins, in particular their selectivity for, and competition between, different ions. Another so far less well investigated major factor
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Inflammatory immunity and bacteriological perspectives: A new direction for copper treatment of sepsis J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-16 Zhenzhen Huang, Lunfei Cao, Dengfeng Yan
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Therapeutic potential of the linalool against cadmium-induced testicular tissue damage J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-15 Tuba Yalçın, Sercan Kaya
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Assessment of carcinogenic and non-carcinogenic risk of exposure to potentially toxic elements in tea infusions: Determination by ICP-OES and multivariate statistical data analysis J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-15 Mahmood Ahmed, Muhammad Ahmad, Muhammad Ayyan Khan, Aamir Sohail, Mudassar Sanaullah, Waqar Ahmad, Dure Najaf Iqbal, Khuram Khalid, Tanveer A. Wani, Seema Zargar
The perennial evergreen tea () plant is one of the most popular nonalcoholic drinks in the world. Fertilizers and industrial, agricultural, and municipal activities are the usual drivers of soil contamination, contaminating tea plants with potentially toxic elements (PTEs). These elements might potentially accumulate to larger amounts in the leaves of plants after being taken up from the soil. Thus
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Assessment of cancer risk and radiological effects from 210Po and 210Pb with consumption of wild medicinal herbal plants J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-14 Aleksandra Moniakowska, Dagmara Strumińska-Parulska
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Evaluation of imprecision in the different detection methods of Zn based on 5 years of data from an external quality assessment program in China J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-12 Chao Zhang, Ying Yan, Chuanbao Zhang
This study examines the imprecision of zinc (Zn) measurements across various clinical detection methods by analyzing the external quality assessment (EQA) data from 2018 to 2022. The findings of this study aim to offer recommendations for enhancing Zn measurements. Participating laboratories were grouped into peer categories based on the detection methods. The robust mean and coefficient of variation
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Concentrations and influencing factors of 17 elements in placenta, cord blood, and maternal blood of women from an e-waste recycling area J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-12 Yacui Luo, Haijun Zhang, Fangzhong Gui, Jiayang Fang, Haijiang Lin, Danhong Qiu, Lingfei Ge, Qiong Wang, Peiwei Xu, Jun Tang
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Investigation of Zinc on hemorheological parameters in a rat model of diabetes J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-10 Nural Pastacı Özsobacı, Denizhan Karış, Alev Meltem Ercan, Derviş Özçelik
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Characterizations of biogenic selenium nanoparticles and their anti-biofilm potential against Streptococcus mutans ATCC 25175 J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-07 Binbin Si, Yang Yang, Muhammad Naveed, Fenghuan Wang, Malik Wajid Hussain Chan
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Drug-induced osteoporosis and mechanisms of bone tissue regeneration through trace elements J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-04 Nayara de Souza da Costa, Luíza Siqueira Lima, Maria Eduarda Andrade Galiciolli, Deborah Helen Fabiano Ribeiro, Milena Mariano Ribeiro, Gisele de Paula Júlia Garica, Isabela Saragioto Marçal, Juliana Ferreira da Silva, Meire Ellen Pereira, Cláudia Sirlene Oliveira, Izonete Cristina Guiloski
Osteoporosis is associated with an imbalance in bone formation, with certain drugs used in disease treatment being implicated in its development. Supplementation with trace elements may contribute to bone regeneration, offering an alternative approach by enhancing bone mineral density (BMD) and thereby thwarting the onset of osteoporosis. This review aims to assess the mechanisms through which trace
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Ameliorative potential of eriocitrin against cadmium instigated hepatotoxicity in rats via regulating Nrf2/keap1 pathway J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-04-04 Muhammad Faisal Hayat, Muhammad Zohaib, Muhammad Umar Ijaz, Moazama Batool, Asma Ashraf, Bader O. Almutairi, Usman Atique
Cadmium (Cd) is a hazardous heavy metal that adversely affects the vital body organs particularly liver. Eriocitrin (ERCN) is a plant-based flavonoid that is well-known for its wide range of pharmacological potential. This research trial was aimed to determine the ameliorative potential of ERCN against Cd provoked hepatotoxicity in rats. Twenty-four rats () were apportioned into control, Cd treated
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Predictors of urinary heavy metal concentrations among pregnant women in Jinan, China J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-30 Jiayi Song, Xiang Wang, Qichen Huang, Chuanling Wei, Dongxia Yang, Cuilan Wang, Kefeng Fan, Shuang Cheng, Xiaohui Guo, Ju Wang
Toxic heavy metal exposure and insufficiency or excess of essential heavy metals may have negative effects on pregnant women’s health and fetal growth. To date, the predictors of pregnant women’s heavy metal exposure levels remain unclear and vary with different regions. The study intended to explore potential predictors of exposure to heavy metals individually and high co-exposure to heavy metal mixtures
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Dietary nano-Selenium supplementation improves growth performance, nutrient digestibility and hematology in Cirrhinus mrigala fingerlings J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-30 Nisar Ahmad, Syed Makhdoom Hussain, Shafaqat Ali, Pallab K. Sarker, Khalid A. Al-Ghanim, Muhammad Mahmood
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Nutritional profile and risk assessment of inorganic elements in enteral and parenteral nutrition formulas J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-27 Iohanna M.N. Ribeiro Menezes, Patricia de A. Nascimento, Rafaella R.A. Peixoto, Andrea Oliveira
The contents of essential (Ca, Fe, K, Na, P, and Zn) and potentially toxic inorganic elements (As, Al, Cd, Cr, Cu, Mn, and Pb) in enteral and parenteral nutrition formulas were evaluated by inductively coupled plasma optical emission spectrometry (ICP OES) and graphite furnace atomic absorption spectrometry (GFAAS). A total of 30 enteral formulas, 23 parenteral solution components, and 3 parenteral
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Determination of copper status by five biomarkers in serum of healthy women J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-22 Thilo Samson Chillon, Max Tuchtenhagen, Maria Schwarz, Julian Hackler, Raban Heller, Peyman Kaghazian, Arash Moghaddam, Lutz Schomburg, Hajo Haase, Anna P. Kipp, Tanja Schwerdtle, Maria Maares
The essential trace element copper is relevant for many important physiological processes. Changes in copper homeostasis can result from disease and affect human health. A reliable assessment of copper status by suitable biomarkers may enable fast detection of subtle changes in copper metabolism. To this end, additional biomarkers besides serum copper and ceruloplasmin (CP) concentrations are required
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Quantitative profiling and baseline intervals of trace elements in healthy lung tissues J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-21 Aleksandar Stojsavljević, Katarina Marković, Aleksandar Lukač, Aleksandar Ristanović, Nebojša Marić, Stefan Marković, Ivana Šarac, Janez Ščančar
Human lung tissue, as an interface with the environment, is susceptible to various environmental pollutants, including trace metals. However, quantitative data on trace metals in human lung tissues remain poorly described. This study aimed to characterize the elemental composition of histologically healthy, unaffected parts of human lung tissues, associated with non-infective, non-infiltrative, and
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Assessment of trace element and mineral levels in students from Turkmenistan in comparison to Iran and Russia J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-20 Anatoly A. Kirichuk, Anatoly V. Skalny, Dirk Schaumlöffel, Irina A. Kovaleva, Tatiana V. Korobeinikova, Andrey S. Kritchenkov, Michael Aschner, Borhan Mansouri, Andrey A. Skalny, Alexey A. Tinkov
Of the present study was to assess essential trace element and mineral levels in serum, hair, and urine of healthy first-year students from Turkmenistan (n = 73) in comparison to students from Iran (n = 78) or Russia (n = 95). Examination of foreign students was performed within two days after arrival to Russia during medical examination prior admission to RUDN University. Serum, hair, and urine trace
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Fabrication of bimetallic Ag@ZnO nanocomposite and its anti-cancer activity on cervical cancer via impeding PI3K/AKT/mTOR pathway J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-20 Qinghua Yin, Qiang Zhou, Jianbing Hu, Jie Weng, Songlian Liu, Leilan Yin, Ling Long, Yajun Tong, Kewei Tang, Site Bai, Ludi Ou
Bimetallic nanoparticles, specifically Zinc oxide (ZnO) and Silver (Ag), continue to much outperform other nanoparticles investigated for a variety of biological uses in the field of cancer therapy. This study introduces biosynthesis of bimetallic silver/zinc oxide nanocomposites (Ag@ZnO NCs) using the extract and evaluates their anti-cancer properties against cervical cancer. The process of generating
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Analysis of relationship between mixed heavy metal exposure and early renal damage based on a weighted quantile sum regression and Bayesian kernel machine regression model J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-19 Qi An, Qingyao Wang, Rujie Liu, Jiachen Zhang, Shuangjing Li, Weitong Shen, Han Zhou, Yufen Liang, Yang Li, Lina Mu, Lijian Lei
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Permanent and decidua dentition as chronological biomarkers of heavy metal contamination: A review of the forensic literature J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-19 Javier Rojas-Torres, María Eugenia González Quijón, Andrés Henríquez-Vidal, Leslie Devia-Rubio, Luis Martínez-Duran
Contamination with heavy metals (HM) has great environmental consequences in the environment due to lack of biodegradation, in addition, accumulation in living beings causes defects in tissues and organs, deteriorating their function and inducing a wide spectrum of diseases. Human biomonitoring consists of the periodic measurement of a certain chemical substance or metabolite in a particular population
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Copper homeostasis and cuproptosis in gynecological disorders: Pathogenic insights and therapeutic implications J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-18 Ying Lin, Ming Yuan, Guoyun Wang
This review comprehensively explores the complex role of copper homeostasis in female reproductive system diseases. As an essential trace element, copper plays a crucial role in various biological functions. Its dysregulation is increasingly recognized as a pivotal factor in the pathogenesis of gynecological disorders. We investigate how copper impacts these diseases, focusing on aspects like oxidative
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Trace elements in bean-to-bar chocolates from Brazil and Ecuador J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-13 Vitor Hugo Burgon, Manuela Luísa Nunes Silva, Raquel Fernanda Milani, Marcelo Antonio Morgano
The high quality and unique flavor and aroma of bean-to-bar chocolates have resulted in an increase in the consumption of these products. Nevertheless, cocoa beans may present inorganic contaminants from environmental and anthropogenic sources which can contribute to contamination of the chocolates, despite the fewer processing steps and few ingredients used in bean-to-bar manufacturing process compared
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Selenium levels in colorectal cancer: A systematic review and meta-analysis of serum, plasma, and colorectal specimens J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-12 Amit Pal, Aninda Dhar, Muhammad Aaqib Shamim, Isha Rani, Ram Rattan Negi, Aaina Sharma, Namrata Chatterjee, Anmol Goyal, Sadashiv, Bandhan Kaur, Vincenzo Tondolo, Mauro Rongioletti, Subha Ranjan Samantaray, Mehboob Hoque, Anil Pawar, Kalyan Goswami, Rosanna Squitti
Colorectal cancer (CRC) is a growing public health problem. Several clinical studies have shown a potentially protective effect of selenium (Se), but the reports are inconsistent. The objective of the study was to examine the evidence for relation between serum/tissue Se status and CRC. In this Systematic Review and Meta-Analysis, we searched Cochrane Library, EBSCOhost, EMBASE, ProQuest, PubMed/MEDLINE
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The magnesium depletion score is associated with increased likelihood of kidney stone disease among female adults J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-12 Ying Xu, Yingyi Qin, Hongtao Lu, Lulu Liu, Weiyan Huang, Anwen Huang, Yufei Ye, Hui Shen, Zhiyong Guo, Wei Chen
The association between magnesium depletion score (MDS) and kidney stone disease (KSD) remains unknown. This study was designed to investigate the association of MDS with KSD in adults. A total of 19,654 participants were enrolled from the National Health and Nutrition Examination Surveys (NHANES). The MDS was calculated by assessing four aspects, including alcohol assumption, renal function, and use
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Evidence for genetic causality between iron homeostasis and Parkinson's disease: A two-sample Mendelian randomization study J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-11 Hong Chen, Xie Wang, Ze Chang, Juan Zhang, Daojun Xie
Parkinson's disease (PD) is a degenerative disease of the central nervous system, and its specific etiology is still unclear. At present, it is believed that the main pathological basis is the reduction of dopamine concentration in the brain striatum. Although many previous studies have believed that iron as an important nutrient element participates in the occurrence and development of PD, whether
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Correlation between urinary rare earth elements and liver function in a Zhuang population aged 35–74 years in Nanning J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-09 Xingxi Luo, Liling Wei, Shun Liu, Kaili Wu, Dongping Huang, Suyang Xiao, Erna Guo, Lei Lei, Xiaoqiang Qiu, Xiaoyun Zeng
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Reference values for metal(loid)s concentrations in the urine samples of healthy Iranian adults: Results from the first nationally representative human biomonitoring study J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-07 Zahra Soleimani, Rosa Haghshenas, Yousef Farzi, Ali Taherkhani, Zahra Shokri Varniab, Maryam Naserinjad, Parnian Abedinjad, Samet salehyan, Abdullah Maeiyat, Fatemeh Gorgani, Saham Mirzaei, Mohsen Abbasi-Kangevari, Kazem Naddafi, Masud Yunesian, Alireza Mesdaghina, Farshad Farzadfar
This study measured the concentrations of arsenic (As), aluminum (Al), cadmium (Cd), chromium (Cr), mercury (Hg), nickel (Ni), and lead (Pb) in the urine samples of the Iranian adult population. This nationally representative study was conducted on 490 participants in six provinces of Iran who were selected based on the clustering method. Participants included healthy Iranian adults aged above 25 years
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Food groups consumption and urinary metal mixtures in women from Northern Mexico J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-07 Ángel Mérida-Ortega, Rodrigo Ugalde-Resano, Alma Rincón-Rubio, Gisela Flores-Collado, M. Karen Flores-García, Karla Rangel-Moreno, Chris Gennings, Lizbeth López-Carrillo
We aimed to evaluate the association between food groups and mixtures of urinary metal concentrations in a sample of women; as well as identify the most important metals within each mixture. This is a cross-sectional analysis between food groups consumption and mixtures of various metals in urine from 439 women, ≥18 years old, from Northen Mexico. We estimated the dietary intake of 20 food groups through
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Reduction of haemoglobin is related to metal mixtures exposure in Chinese preschoolers: Joint effect models J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-05 Ye Fu, Minghui He, Yang Liu, Mingzhu Li, Meiqin Zhu, Yan Wang, Wei Lin, Lili Yu, Liting Yang, Yao Zhang, Yanli Liu, Hongxian Ji, Hongcheng Ding, Jing Wang
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Plasma levels and dietary intake of minerals in patients with type 2 diabetes and chronic kidney disease: A case-control study J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-04 Mudili Sivaprasad, Tattari Shalini, Manisha Sahay, Rakesh Sahay, Manavalan Satyanarayanan, G. Bhanuprakash Reddy
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease (CKD) worldwide. Altered mineral levels leading to adverse outcomes are widely reported in diabetes but limited in DKD, in the Indian scenario, hence this study was taken up to address this issue. A hospital-based case-control study was taken up with 54 healthy controls (C) and 140 subjects with type 2 diabetes wherein 74
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The biotoxic effects of heavy metals exposure in miners and non-miners J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-04 Narjes Soltani, Tabandeh Sadeghi, Mohammad Reza Mahmoodi, Majid Saadloo, Mohammad Reza Baneshi, Zohreh Rajabi, Ali Shamsizadeh
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Chronic dietary iron overload affects hepatic iron metabolism and cognitive behavior in Wistar rats J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-02 Padmaja Anil Shete, Niraj Sudhir Ghatpande, Mokshada Evameshwar Varma, Pranav Vijay Joshi, Komal Ravindra Suryavanshi, Ashwini Vivek Misar, Sachin Hanumantrao Jadhav, Priti Parag Apte, Prasad Padmakar Kulkarni
Iron accumulation in organs affects iron metabolism, leading to deleterious effects on the body. Previously, it was studied that high dietary iron in various forms and concentrations influences iron metabolism, resulting in iron accumulation in the liver and spleen and cognitive impairment. However, the actual mechanism and impact of long-term exposure to high dietary iron remain unknown. As a result
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Essential trace element levels in multiple sclerosis: Bridging demographic and clinical gaps, assessing the need for supplementation J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-03-02 Aleksandar Stojsavljević, Jovana Jagodić, Slađan Pavlović, Evica Dinčić, Jovana Kuveljić, Dragan Manojlović, Maja Živković
Multiple sclerosis (MS) is a chronic demyelinating disorder intricately linked to perturbations in trace element levels. While previous studies have explored circulating trace elements in a limited sample, understanding the impact of demographic and clinical variables on the elemental profile within a larger cohort remains elusive. This study aimed to evaluate essential trace elements (Cr, Mn, Co,
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Response surface methodology optimizes selenium inhibition of prostate cancer PC-3 cell viability J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-28 Andrew Whitcomb, Xiuqi Li, John Lawson, Merrill Christensen
The rising incidence of prostate cancer in the U.S. necessitates innovative therapeutic approaches to this disease. Though extensive research has studied Selenium as an anticarcinogen against prostate cancer, results have varied due to overlooked experimental confounds. Recent studies have identified differential effects of various selenium compounds on prostate cancer cells. This study leverages Mixture
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Correlations between bone metabolism biomarkers and fluoride exposure in adults and children J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-28 Shuo Yang, Shuiyuan Yu, Yuhui Du, Zichen Feng, Xuecheng Jiao, Qinyang Li, Jingjing Wu, Lei Sun, Juan Zuo, Xiaoli Fu, Zhiyuan Li, Hui Huang, Guoyu Zhou, Fangfang Yu, Yue Ba
Increased exposure to fluoride, which notably affects bone metabolism, is a global concern. However, the correlations and sensitivity of bone metabolism to fluoride remain controversial. In this cross-sectional study, 549 children (aged 7–12 years) and 504 adults (≥ 18 years old) were recruited in the high-fluoride areas of the Henan Province. Urinary fluoride (UF) level was determined using a fluoride
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Are lead, cadmium and mercury risk factors for resistant hypertension? J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-28 Arturo Corbatón Anchuelo, Nieves Martell Claros, María Abad Cardiel, José Antonio García Donaire, Manuel Fuentes Ferrer, Adrián Bravo Gómez, Elena Llorente Martín, Angielys Zamora Trillo, Gonzalo Bonmatí Torres, Montserrat González-Estecha
Lead (Pb), cadmium (Cd) and mercury (Hg) are toxic trace elements that represent a public health problem as risk factors for cardiovascular disease and hypertension (HT) and could also contribute to the development of resistant hypertension (rHT) To compare the blood concentrations of Pb, Cd and Hg in subjects with resistant and non-resistant HT and to define whether there is a relationship between
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Corrigendum to “Arsenic exposure and pulmonary function decline: Potential mediating role of TRAIL in chronic obstructive pulmonary disease patients” [J. Trace Elem. Med. Biol. 83 (2024) 127415] J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-27 Ying Liu, Feng-Min Zhu, Juan Xu, You-Peng Deng, Jing Sun, Qi-Yuan He, Zhen-Yu Cheng, Min-Min Tang, Jin Yang, Lin Fu, Hui Zhao
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Selenium protects against Pb-induced renal oxidative injury in weaning rats and human renal tubular epithelial cells through activating NRF2 J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-27 Chongmei Tian, Yu Qiu, Yaping Zhao, Liping Fu, Daozong Xia, Junjie Ying
Lead (Pb) poisoning posing a crucial health risk, especially among children, causing devastating damage not only to brain development, but also to kidney function. Thus, an urgent need persists to identify highly effective, safe, and low-toxicity drugs for the treatment of Pb poisoning. The present study focused on exploring the protective effects of Se on Pb-induced nephrotoxicity in weaning rats
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Associations of multiple metal intake with all-cause and cardiovascular mortality in US adults stratified by age and sex: A prospective cohort from the NHANES database study J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-21 Ziyi Liu, Jiyuan Li, Qing Chen, Xue Zhao, Fenghua Peng, Hongliang Zhang
The relationship between dietary metal intake and mortality risk is controversial, and we investigated the relationship between intake of five metals (iron, copper, selenium, zinc, and magnesium) and all-cause, cardiovascular mortality in the total population, gender subgroups, and age subgroups. 17,207 participants from the National Health and Nutrition Examination Survey (NHANES) database from 2009
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The association between endothelial function and autoimmune thyroiditis induced by iodine excess J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-17 Dandan Wang, Peng Li, Zheng Zhou, Meihui Jin, Baoxiang Li, Fan Li, Hongmei Shen
Iodine excess (IE) intake leads to lymphocyte dysfunction and contributes to autoimmune thyroiditis (AIT). Abnormal thyroid function is associated with adverse cardiovascular events, endothelial dysfunction is often an early pathophysiological feature in most cardiovascular disease. However, the relationship between iodine and the cardiovascular system is currently unclear. Therefore, the aim of this
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Arsenic exposure and pulmonary function decline: Potential mediating role of TRAIL in chronic obstructive pulmonary disease patients J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-17 Ying Liu, Feng-Min Zhu, Juan Xu, You-Peng Deng, Jing Sun, Qi-Yuan He, Zhen-Yu Cheng, Min-Min Tang, Jin Yang, Lin Fu, Hui Zhao
Environmental arsenic (As) exposure is strongly related to the progression of chronic obstructive pulmonary disease (COPD). Pulmonary epithelial cells apoptosis is implicated in the pathophysiological mechanisms of COPD. However, the role of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL), one biomarker of apoptosis, remains unclear in As-mediated pulmonary function alternations in
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Exposure to zinc oxide nanoparticles induced reproductive toxicities in male Sprague Dawley rats J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-12 Nagina Rehman, Farhat Jabeen, Muhammad Asad, Aneela Nijabat, Amir Ali, Safir Ullah Khan, Juan Pedro Luna-Arias, Zia-ur-Rehman Mashwani, Ayesha Siddiqa, Adhimoolam Karthikeyan, Ajaz Ahmad
This research delves into the reproductive toxicology of zinc oxide nanoparticles (ZnO-NPs) in male Sprague Dawley rats. It specifically examines the repercussions of Zn accumulation in the testes, alterations in testosterone levels, and histopathological changes in the gonadal tissues. The primary objective of this study is to elucidate the extent of reproductive toxicity induced by ZnO-NPs in male
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Relationship between heavy metal concentrations and Chronic kidney disease in population of Hoveyzeh cohort study: A cross-sectional study in Iran J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-09 Mehrsa Drikvandi, Sahand Jorfi, Bahman Cheraghian, Mehdi Ahmadi
Chronic kidney disease (CKD) is a multifactorial disease whose prevalence is increasing worldwide. CKD affects 700 million to 1 billion people worldwide, with a prevalence of 9.1% to 13.4%. In Iran, the reported prevalence of CKD is 15.14%, even higher than the global prevalence. Some studies introduced heavy metals as possible risk factors of CKD. We conducted the first study in Iran to examine the
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Corrigendum to “Antiviral potential of nanoparticles for the treatment of Coronavirus infections” [J. Trace Elem. Med. Biol. 72 (2022) 1–17] J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-08 Joy Sarkar, Sunandana Das, Sahasrabdi Aich, Prithu Bhattacharyya, Krishnendu Acharya
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Dosage-effect of selenium supplementation on blood glucose and oxidative stress in type 2 diabetes mellitus and normal mice J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-07 Xiaxia Cai, Zhuo Hu, Mingyuan Zhang, Qinyu Dang, Qian Yang, Xiaoyan Zhao, Yandi Zhu, Yadi Zhang, Yuchen Wei, Haiqin Fang, Huanling Yu
The effectiveness of selenium (Se) supplementation on glycemic control is disparate. Objective: This study aims to evaluate the effects of different dosages of Se diets on the blood glucose in type 2 diabetes mellitus (T2DM, db/db) and normal (db/m) mice. Methods: The db/db and db/m mice were fed with different dosages of Se supplemented diets (0, 0.1, 0.3, 0.9, 2.7 mg/kg) for 12 weeks, respectively
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Oral exposure to food grade titanium dioxide (E171) induces intestinal and behavioural alterations in adult mice but limited effects in young mice J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-05 Carolina Rodríguez-Ibarra, Daniel Díaz-Urbina, Alejandro A. Zagal-Salinas, Estefany I. Medina-Reyes, Alejandro Déciga-Alcaraz, Rogelio Hernández-Pando, Yolanda I. Chirino
Food-grade titanium dioxide (E171), a white colourant widely used in ultra-processed food products, has been banned in the European Union. However, its usage is still permitted in medicines, and in several other countries. The estimated intake of E171 in children is higher than in adults, which led us to hypothesise that E171 induces differential effects depending on age, with adult mice being the
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Polymer-clay nanofibrous wound dressing materials containing different boron compounds J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-03 Sara Asghari Dilmani, Sena Koç, Tülay Selin Erkut, Menemşe Gümüşderelioğlu
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Zinc as a potential regulator of the BCR-ABL oncogene in chronic myelocytic leukemia cells J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-02 Bo Zhu, Longshuo Sun, Zhonghua Li, Pengyou Shang, Chunhao Yang, Kaiqiang Li, Jiahuang Li, Qi Zhi, Zichun Hua
Generally, decreased zinc in the serum of tumor patients but increased zinc in tumor cells can be observed. However, the role of zinc homeostasis in myeloid leukemia remains elusive. is essential for the initiation, maintenance, and progression of chronic myelocytic leukemia (CML). We are currently investigating the association between zinc homeostasis and CML. Genes involved in zinc homeostasis were
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Metallic nanoparticles and treatment of cutaneous leishmaniasis: A systematic review J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-01 Rhanoica Oliveira Guerra, José Rodrigues do Carmo Neto, Priscilla Elias Ferreira da Silva, Pablo Igor Ribeiro Franco, Rafaela Miranda Barbosa, Tarcísio de Albuquerque Martins, Juliana Costa-Madeira, Thais Soares Farnesi de Assunção, Carlo José Freire de Oliveira, Juliana Reis Machado, Luciana de Almeida Silva Teixeira, Wellington Francisco Rodrigues, Virmondes Rodrigues Júnior, Anielle Christine Almeida
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Trace and essential elements as vital components to improve the performance of the male reproductive system: Implications in cell signaling pathways J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-01 Ali Morabbi, Mohammad Karimian
Successful male fertilization requires the main processes such as normal spermatogenesis, sperm capacitation, hyperactivation, and acrosome reaction. The progress of these processes depends on some endogenous and exogenous factors. So, the optimal level of ions and essential and rare elements such as selenium, zinc, copper, iron, manganese, calcium, and so on in various types of cells of the reproductive
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Boric acid and Molybdenum trioxide synergistically stimulate osteogenic differentiation of human bone marrow-derived mesenchymal stromal cells J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-01 A. Scheurle, E. Kunisch, A.R. Boccaccini, T. Walker, T. Renkawitz, F. Westhauser
Metals and their metal ions have been shown to exhibit certain biological functions that make them attractive for use in biomaterials, for example in bone tissue engineering (BTE) applications. Recent data shows that Molybdenum (Mo) is a potent inducer of osteogenic differentiation in human bone marrow-derived mesenchymal stromal cells (BMSCs). On the other hand, while boron (B) has been shown to enhance
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Association of blood cadmium levels and all-cause mortality among adults with rheumatoid arthritis: The NHANES cohort study J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-02-01 Haobiao Liu, Mian Liu, Lichun Qiao, Zhihao Yang, Yujie He, Miaoye Bao, Xue Lin, Jing Han
The potential impact of environmental cadmium exposure on the prognosis of patients with rheumatoid arthritis (RA) remains unclear, despite its known association with various adverse health outcomes. In this study, a total of 1285 RA patients were included in the National Health and Nutrition Examination Survey (NHANES) conducted between 2003 and 2016. The Cox regression model was employed to investigate
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In vitro digestion and characterization of selenized Saccharomyces cerevisiae, Pichia fermentans and probiotic Saccharomyces boulardii J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-01-30 Ivana Hyrslova, Antonin Kana, Vera Nesporova, Iva Mrvikova, Agapi I. Doulgeraki, Barbora Lampova, Ivo Doskocil, Sarka Musilova, Marek Kieliszek, Gabriela Krausova
Yeasts have the remarkable capability to transform and integrate inorganic selenium into their cellular structures, thereby enhancing its bioavailability and reducing its toxicity. In recent years, yeasts have attracted attention as potential alternative sources of protein. This study explores the selenium accumulation potential of two less explored yeast strains, namely the probiotic CCDM 2020 and
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Doping zinc oxide and titanium dioxide nanoparticles with gold induces additional oxidative stress, membrane damage, and neurotoxicity in Mytilus galloprovincialis: Results from a laboratory bioassay J. Trace Elem. Med. Bio. (IF 3.5) Pub Date : 2024-01-29 Imen Bouzidi, Abdelhafidh Khazri, Karine Mougin, Wejden Bendhafer, Abdelghafar M. Abu-Elsaoud, Oana-Alexandra Plavan, Mohamed A.M. Ali, Gabriel Plavan, Sadin Özdemir, Hamouda Beyrem, Fehmi Boufahja, Badreddine Sellami
While previous studies have provided insights into the effects of zinc oxide (ZnO) and titanium dioxide (TiO) nanoparticles (NPs) on aquatic organisms, there is still a substantial amount of information lacking about the possible effects of their doped counterparts. The goal of the current work was to address this gap by examining reaction to exposure to doped and undoped nanoparticles. Two concentrations