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UK Transfusion Laboratory Collaborative: Minimum standards for staff qualifications, training, competency and the use of information technology in hospital transfusion laboratories 2023 Transfus. Med. (IF 1.5) Pub Date : 2024-02-13 Kerry Dowling, Jennifer Davies, Shruthi Narayan, Victoria Tuckley, Chris Robbie, Chris Ward, Caroline Subramaniam, Claire Whitham, Tracey Tomlinson, Georgia Stephens, Anne Thomson, Sinead Carty, Anna Capps-Jenner, Dan Willis
CONFLICT OF INTEREST STATEMENT The authors declare no conflicts of interest.
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Guidelines for the specification, implementation and management of IT systems in hospital transfusion laboratories Transfus. Med. (IF 1.5) Pub Date : 2024-01-24 Julie Staves, Paul Ashford, Tom Bullock, Tony Coates, Linda Lodge, Nishil Patel, Megan Rowley, Nigel Sargant, Chloë E. George
CONFLICT OF INTEREST STATEMENT The BSH paid the expenses incurred during the writing of this guidance. All authors have made a declaration of interest to the BSH and Task Force Chairs which may be viewed on request.
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Impact of the COVID-19 outbreak on blood supply in two large university hospitals Transfus. Med. (IF 1.5) Pub Date : 2024-01-23 Christian M. Brieske, Christian Temme, Jens Hiller, Meike Goebel, Sven Peine, Peter A. Horn
This study aimed to examine the relationship between the decrease in elective procedures and the need for blood donation during the novel coronavirus disease (COVID-19) pandemic at university hospitals.
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Suggested blood donor deferral strategy regarding hepatitis B infections in China Transfus. Med. (IF 1.5) Pub Date : 2024-01-23 Ling Li, Rui Wang, Jin Guo, Liu He, Zhengmin Liu, Qianqian Qin, Jing Zhang, Shuo Wu, Liqin Huang, Hongwei Ge, Zhong Liu
Hepatitis B virus (HBV) reactivity in individual immunologic and nucleic acid tests (NAT) tests does not represent the true infectious status of the blood donor. This study discusses the use of confirmatory tests to determine when deferral of blood donors is appropriate.
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Validation of the Sysmex XN analyser and Blood Bank mode for the quality and safety of donor blood and transfusion products Transfus. Med. (IF 1.5) Pub Date : 2024-01-09 Ondrej Valina, Ida Vankova, Konstantinos Mintzas, Klara Knappova, Zdenka Gasova
Our objective was to compare the measurement of residual white blood cell (rWBC) and residual red blood cell (rRBC) counts in blood products using the XN Blood Bank mode and the laboratory standard operating procedures for manual counts. In addition, to compare the whole blood complete blood count (CBC) values of blood donors and the quality of blood products using the Sysmex XN analyser versus the
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Prevention strategies for vasovagal reaction in whole blood donors: A quadri-armed randomised control trial Transfus. Med. (IF 1.5) Pub Date : 2024-01-02 Radheshyam Meher, Gopal Kumar Patidar, Rahul Chaurasia, Hem Chandra Pandey, Anjali Hazarika
Vasovagal reaction (VVR) is a frequently encountered generalised donor adverse reaction, associated with donor deterrence towards future donation. Several mitigation strategies for prevention of VVR were tried but still not standardised. This quadri-armed randomised study evaluated the utility of water ingestion, applied muscle tension (AMT) and combination of both in preventing the VVR among blood
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Prevalence, incidence, risk factors and residual risk associated with viral infections among eligible Brazilian blood donors Transfus. Med. (IF 1.5) Pub Date : 2024-01-02 Ana Paula Alves Santos, Danyelle Romana Alves Rios, Clara Lemos Carneiro Trindade, Fernanda Eshtefane Garrides Oliveira, Milena Batista Oliveira, Saulo Nascimento de Melo, Vinícius Silva Belo
Knowledge regarding the profile of eligible blood donors presenting positive results in laboratory screening is essential for reducing transfusion-transmitted human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV). Our study aimed to evaluate the prevalence, incidence, predictor variables and residual risk (RR) of HIV/HBV/HCV in blood bags donated in Minas Gerais, Brazil
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Analysis of a 5-year, evidenced-based, rational blood utilisation project in a South African regional hospital Transfus. Med. (IF 1.5) Pub Date : 2023-12-28 Robert Wise, Kirsten Hood, David Bishop, Gary Sharp, Reitze Rodseth
Blood products are a lifesaving but limited resource, particularly in resource-limited settings. Evidence-based transfusion criteria tailored to local hospitals have shown great promise in reducing costs, minimising shortages, and ameliorating the morbidity and mortality associated with liberal blood product usage. We implemented the “Saving Blood, Saving Lives” project to: promote responsible blood
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Role of disruptions in O RhD negative donations in Colombia on increasing maternal mortality ratio from haemorrhage Transfus. Med. (IF 1.5) Pub Date : 2023-12-27 María-Isabel Bermúdez-Forero, Diana-Carolina Delgado-López, Diego-Alexander Anzola-Samudio, Fernando Palomino, Michel-Andres Garcia-Otalora
The aim of this work was to evaluate the relationship of the maternal mortality ratio due to obstetric haemorrhage (MMROH) with the national blood donations, particularly O RhD negative (Oneg) before and during COVID-19 pandemic.
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The influence of the COVID-19 pandemic on blood donation and supply in China Transfus. Med. (IF 1.5) Pub Date : 2023-12-27 Si-cong Yu, Yun-tai Yao
During the COVID-19 pandemic, there was a sharp decline in blood donation which posed a serious threat to the clinical blood supply worldwide. The aim of this study was to evaluate the influence of the COVID-19 pandemic on blood donation and supply in China on a nationwide level.
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Utility of rotational thromboelastometry in the management of massive haemorrhage at a regional Australian hospital Transfus. Med. (IF 1.5) Pub Date : 2023-11-29 Yu-Hsuan Liu, Jessica Sia, Azhar Munas, Catherine Tacon, Kris Salaveria, Harrison Langa Lutshaba, Josh Hanson
Rotational thromboelastometry (ROTEM) allows targeted and individualised blood product replacement.
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A novel homozygous splice-site mutation of JK gene leads to Jk(a-b-) phenotype Transfus. Med. (IF 1.5) Pub Date : 2023-11-10 Jiaxuan Yang, Lina Ni, Aijing Li, Minghao Li, Shulin Ruan, Dong Xiang, Ziyan Zhu, Luyi Ye
This study aimed to investigate the molecular mechanism of the Jk(a-b-) phenotype in a Chinese transfusion patient.
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Intravenous immunoglobulin alteration in response to adverse reactions in neurological conditions: A retrospective cohort study Transfus. Med. (IF 1.5) Pub Date : 2023-11-14 Melinda Jiang, Lydia Lam, Joshua G. Kovoor, James Kimber, Aashray K. Gupta, Brandon Stretton, Rudy Goh, Stephen Bacchi
Intravenous immunoglobulin (IVIg) is an important treatment in a range of neurological conditions. There is currently limited evidence regarding the frequency and management of IVIg-associated adverse reactions (AR) in neurological disorders.
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Reactions to serum eye drops—New Zealand experience and review of the literature Transfus. Med. (IF 1.5) Pub Date : 2023-11-10 Krishna G. Badami, Malcolm McKellar
Serum eye drops (SED) are used to treat ocular surface disease. Reactions to SED are poorly documented.
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Apparent changes in RhD status during pregnancy: A case study of weak D variant due to RHD*DAU-2. Transfus. Med. (IF 1.5) Pub Date : 2023-11-10 Matthew Holt,Shane Grimsley,Matthew Hazell,Tom Bullock,Tracey Watson,Laura Eastwood,Rachel Allan,Marina Karakantza
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Recurrent pregnancy loss in a patient with anti-Rh17 Transfus. Med. (IF 1.5) Pub Date : 2023-11-08 Bushra Moiz, Muhammed Salman, Seher Rasheed, Ruhul Qudus, Glenda Millard, Catherine A. Hyland, Robert L. Flower, Brett Wilson, Robyn Turner, Genghis H. Lopez, Yew-Wah Liew
Rh is one of the most important blood group systems in transfusion medicine. The two homologous genes RHD and RHCE are located on chromosome 1p36.11 and encode for RhD and RhCE proteins, respectively. Complex genetic polymorphisms result in a variety of antigenic expression of D, C, E, c, and e. Here, we describe a case of a young female with D−− who developed anti-Rh17 secondary to blood transfusion
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Prevalence and incidence of transfusion-transmissible infections among blood donors in Malawi: A population-level study Transfus. Med. (IF 1.5) Pub Date : 2023-10-12 Emmanuel Singogo, Maganizo Chagomerana, Collin Van Ryn, Robert M'bwana, Andrew Likaka, Bridon M'baya, Sydney Puerto-Meredith, Effie Chipeta, Victor Mwapasa, Adamson Muula, Cavan Reilly, Mina C. Hosseinipour
Voluntary non-remunerated blood donors (VNRBDs) are essential to sustain national blood supplies. Expanding testing capacity for the major transfusion-transmitted infections (TTI) is crucial to ensure safe blood products. Understanding trends in TTIs can inform prioritisation of resources.
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Tuesday 10 October 2023 Sig Session Transfus. Med. (IF 1.5) Pub Date : 2023-10-06
SIG 1: BLOOD BANK TECHNOLOGY SIG
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Wednesday 11 October 2023 Simultaneous Sessions Transfus. Med. (IF 1.5) Pub Date : 2023-10-06
SS1 MARGARET KENWRIGHT AWARDS
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Thursday 12 October 2023 Transfus. Med. (IF 1.5) Pub Date : 2023-10-06
SS8 EDUCATION SESSIONS–EDUCATION COURSES/RESOURCES FOR SCIENTIFIC AND CLINICAL COLLEAGUES
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Poster Presentations Transfus. Med. (IF 1.5) Pub Date : 2023-10-06
Theme: Blood donation (including donor safety)
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Author Index Transfus. Med. (IF 1.5) Pub Date : 2023-10-06
A Abbas, Rabiat 16, 15 Abdalla, Saif Elden B. 34 Abdulla, Sam 84 Aboud, Zainab 101 Adams, Helen 104 Adams, M 79 Adegboye, Oluwatobi 42, 43 Adeturinmo, Mary 123 Adewole, Taiwo 17 Agarwal, Nikhil 106 Ahmed, Izza 60 Ainger, Elise 35 Akhtar, Naim 18 Akhtar, Shazia 41 Ali, Natasha 76 Alimam, Samah 71 Aliu, Syntyche 15 Allard, Shubha 18 Amedu, Omale Joseph 15 Amedu, Omale Joseph 16 Anand, Rekha 55, 18 Anbazhagan
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Comparing transfusion practice at multiple hospitals using electronically collected and analysed data Transfus. Med. (IF 1.5) Pub Date : 2023-10-02 Ross D'Souza, Amanpreet Singh Dhesi, Kate Pendry, Andrew Charlton, Sophie Staples, Nicholas A. Watkins, Michael F. Murphy
Comparisons of transfusion practice between organisations are time-consuming using manual methods for data collection. We performed a feasibility study to determine whether large-scale transfusion data from three English hospitals could be combined to allow comparisons of transfusion practice.
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SHOT UK Collaborative Reviewing and Reforming IT Processes in Transfusion (SCRIPT) survey: Laboratory information management systems: Are we ready for digital transformation? Transfus. Med. (IF 1.5) Pub Date : 2023-09-30 Jennifer Davies, Victoria Tuckley, Alistair McGrann, Megan Rowley, Heather Clarke, Peter Baker, Shruthi Narayan
To understand the use, functionality and interoperability of laboratory information management systems (LIMS) in UK transfusion laboratories.
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How do we translate gaps and unmet needs of blood management for thalassemia into a collaborative implementation framework? Transfus. Med. (IF 1.5) Pub Date : 2023-09-29 Chanin Limwongse, Ponlapat Rojnuckarin, Pawinee Kupatawintu, Aphisit Thongthaisin, Parichart Permpikul, Pimpan Kitpoka, Phandee Watanaboonyongcharoen, Pranee Sucharitchan, Kitti Torcharus, Suthat Fucharoen, Khachen Kongpakwattana, Osot Nerapusee, Suporn Chuncharunee
The mainstay of management for thalassemia is regular blood transfusions. However, gaps and unmet needs of blood services for thalassemia are still not clearly identified and addressed in Thailand, a country prevalent with thalassemia. What can be a collaborative implementation framework that helps advance practices and policies relating to blood management for thalassemia?
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Introduction of EUBIS standards to upgrade inspections of blood establishments to improve the safety of blood transfusion: The Polish experience Transfus. Med. (IF 1.5) Pub Date : 2023-09-21 Elżbieta Lachert, Jolanta Antoniewicz-Papis, Agata Mikołowska, Jolanta Kubis, Zbigniew M. Szczepiorkowski, Magdalena Łętowska
The competent authority (CA) responsible for external inspections of Polish blood establishments (BEs) and supervision of the quality system is the Institute of Haematology and Transfusion Medicine (IHTM). Before the implementation of the European Blood Inspection System (EuBIS) classification of non-compliance, the IHTM inspections were conducted according to national guidelines and the non-compliance-related
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Does decreasing the incubation period used in the antibody screen affect its sensitivity? Transfus. Med. (IF 1.5) Pub Date : 2023-09-20 Grace Kenneday, Hui Jun Chih, Susan Finch, Paul Ellery
Pre-transfusion testing (PTT) encompasses a set of mandatory laboratory tests performed before red blood cell transfusion. The antibody screen, one component of PTT, commonly includes a 10–20 min incubation. The primary aim of this study was to determine if this period can be reduced when using current immunohematology methodologies.
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The ongoing dilemma of prophylactic platelet transfusions pre-procedure and the development of evidence-based recommendations. Transfus. Med. (IF 1.5) Pub Date : 2023-09-15 Simon J Stanworth,Akshay Shah,James Doidge,Peter Watkinson,
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A challenge for blood management: A patient presenting anti-Vel antibody undergoing orthotopic liver transplantation. Transfus. Med. (IF 1.5) Pub Date : 2023-09-06 Valéria de Freitas Dutra,Ana Paula Hitomi Yokoyama,Marcelo Bruno de Rezende,Guilherme Eduardo Gonçalves Felga,José Mauro Kutner,Carolina Bonet-Bub
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Low-titer group O whole blood in military ground ambulances: Lessons from the Israel Defense Forces initial experience Transfus. Med. (IF 1.5) Pub Date : 2023-09-05 Tomer Talmy, Michael Malkin, Akiva Esterson, Mark H. Yazer, Anat Sebbag, Avi Shina, Eilat Shinar, Elon Glassberg, Sami Gendler, Ofer Almog
Cold-stored low-titer group O whole blood (LTOWB) has become increasingly utilised in both prehospital and in-hospital settings for resuscitation of traumatic haemorrhage. However, implementing the use of LTOWB to ground medical teams has been limited due to logistic challenges.
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Virological safety of the UK blood supply in the era of individual risk assessments and HIV PrEP Transfus. Med. (IF 1.5) Pub Date : 2023-09-05 Victoria Maddox, Pamela Vallely, Susan R. Brailsford, Heli Harvala
A more individualised donor selection policy was implemented in the UK in 2021, which replaced the previous 3-month deferral for men who have sex with men (MSM). Other blood services have a variety of policies in place to ensure the virological safety of blood components, ranging from an indefinite ban on MSM, to a defined period of exclusion, or to an individualised risk assessment that is not based
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Systematic review of prevalence and risk factors of transfusion transmissible infections among blood donors, and blood safety improvements in Southern Africa Transfus. Med. (IF 1.5) Pub Date : 2023-08-28 Sydney Puerto-Meredith, Emmanuel Singogo, Maganizo Chagomerana, Tiya Nthani, Andrew Likaka, Austrida Gondwe, Bridon M'baya, Mina C. Hosseinipour
Blood and blood products are listed as one of the essential medicines by the World Health Organization (WHO). In addition to inadequate supply, most sub-Saharan Africa (SSA) nations fail to meet their blood needs because many donated blood units are discarded because they are contaminated with transfusion-transmitted infections (TTIs). We sought to estimate the prevalence of TTIs, identify the risk
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Exploring the increasing need for plasma collection: Perspectives of voluntary nonremunerated donors on payment for plasma in Canada Transfus. Med. (IF 1.5) Pub Date : 2023-08-20 Kelly Holloway
The aim of this paper is to understand how voluntary nonremunerated plasma donors in Canada view payment for plasma and the emerging commercial sector.
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Paroxysmal cold hemoglobinuria: A diagnostic dilemma in a paediatric patient Transfus. Med. (IF 1.5) Pub Date : 2023-08-13 Keenan O. Hogan, Gabor Oroszi
Autoimmune hemolytic anaemia is rare in the paediatric population. Differentiation of the underlying aetiology is complicated by heterogeneity in diagnostic criteria and testing strategies. Paroxysmal cold hemoglobinuria (PCH) is an uncommon form of paediatric autoimmune hemolytic anaemia. Identification of the causative biphasic hemolysin requires clinical recognition and access to the Donath-Landsteiner
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Preventative plasmapheresis in a diabetic pregnant patient with hypertriglyceridemia and distal pancreatectomy Transfus. Med. (IF 1.5) Pub Date : 2023-08-10 Keenan O. Hogan
Pregnant patients with a history of hypertriglyceridemia are at increased risk for development of acute pancreatitis. When conservative management fails to maintain triglyceride levels less than 250–500 mg dL−1, implementation of pregnancy category C medications to prevent pancreatitis must be considered. Plasmapheresis rapidly reduces triglyceride levels and has been reported as a successful third-line
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Severe fetal anaemia due to red cell alloimmunisation in a Rhnull woman: A case report Transfus. Med. (IF 1.5) Pub Date : 2023-08-10 Nadège Cuvellier, Andrew Carlin, Dominique A. Badr, Hanane El-Kenz, Isabelle Ruth, Jacques C. Jani
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest.
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Quantitative increases of extracellular vesicles in prolonged cold storage of platelets increases the potential to enhance fibrin clot formation Transfus. Med. (IF 1.5) Pub Date : 2023-08-08 J. Nash, A. Davies, C. V. Saunders, C. E. George, J. O. Williams, P. E. James
Platelet derived extracellular vesicles (EVs) display a pro-coagulant phenotype and are generated throughout platelet concentrate (PC) storage. Cold storage (CS) of PCs is thought to provide a superior haemostatic advantage over room temperature (RT) storage and could prolong the storage time. However, the effect of storage conditions on EV generation and PC function is unknown. We investigated EV
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Evaluation of Dengue, Zika virus, and Chikungunya virus transmission by blood components in recipients of haematopoietic stem cell transplantation Transfus. Med. (IF 1.5) Pub Date : 2023-08-01 Fernando Nivaldo de Oliveira, Suzete Cleusa Ferreira, Anna Shoko Nishiya, Alfredo Mendrone-Junior, Marjorie Vieira Batista, Vanderson Rocha, Silvia Figueiredo Costa
Brazil has a high prevalence of arboviruses, especially Dengue (DENV), Zika (ZKV), and Chikungunya (CHKV).
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Investigation of the effect of pre-analytical factors on particle concentration and size in cryoprecipitate using nanoparticle tracking analysis Transfus. Med. (IF 1.5) Pub Date : 2023-07-22 Ji Hui Hwang, John-Paul Tung, Damien G. Harkin, Robert L. Flower, Natalie M. Pecheniuk
Cryoprecipitate is used primarily to replenish fibrinogen levels in patients. Little is known about the presence of micro- or nano-sized particles in cryoprecipitate. Therefore, we aimed to quantify these particles and investigate some pre-analytical considerations.
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Double or nothing: Costs of duplicate haematinic ordering in medical inpatients. Transfus. Med. (IF 1.5) Pub Date : 2023-06-29 Thomas Jackson Wiseman,Sheryn Tan,Brandon Stretton,Joshua Kovoor,Aashray Gupta,Jack Fabian,Weng Onn Chan,James Malycha,Samuel Gluck,Toby Gilbert,Andrew C Zannettino,Stephen Bacchi
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Plasma exchange in acute hemolytic reaction due to ABO-incompatible erythrocyte concentrate transfusions: Single center experience Transfus. Med. (IF 1.5) Pub Date : 2023-06-28 Neslihan Andıç, Hava Üsküdar Teke, Eren Gündüz
Acute hemolytic transfusion reaction (AHTR) due to ABO-incompatible erythrocyte concentrate (EC) is one of the most catastrophic complications of transfusion. Since the hemolysis is intravascular; hemoglobinemia and hemoglobinuria result in disseminated intravascular coagulation (DIC), acute renal failure, shock, and sometimes death.
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Effects of storage on quality and function of acid-treated platelets with reduced HLA Class I surface expression Transfus. Med. (IF 1.5) Pub Date : 2023-06-25 Mohammad Reza Mirlashari, Annette Vetlesen, Lise Sofie H. Nissen-Meyer, Geir Hetland
Refractory patients need to be provided with HLA-matched platelets (PLTs), which require time-consuming cross-matching. Treatment of PLTs with citric acid leads to denaturation of the HLA Class I complexes without significant damage to the PLTs. HLA Class I depleted PLTs could alternatively be used to HLA-matched PLTs for transfusion. These PLTs have verified normal function up to 4–6 h after acid
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Re-examine the transfusion transmitted risk of SARS-CoV-2 virus during a major COVID-19 outbreak in 2022 Transfus. Med. (IF 1.5) Pub Date : 2023-06-07 S. C. Ng, A. W. H. Chu, W. M. Chan, C. C. Y. Yip, K. H. Leung, C. K. So, J. N. S. Leung, K. K. W. To, C. K. Lee
Although no case of COVID-19 transmission through transfusion has been reported, blood transfusion service (BTS) continues to implement pre-donation and post-donation measures to minimise the risk. In year 2022, when local healthcare system was badly impacted by a major outbreak, it opened an opportunity to re-examine the viraemia risk in these asymptomatic donors.
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Hypophosphatemia related to intravenous iron therapy with ferric carboxymaltose: A case series Transfus. Med. (IF 1.5) Pub Date : 2023-06-01 Nigel Wei-Peng Seng, Jason Bae Barco, Marc Hai-Liang Wong, Kai-Xiong Lim, Wee-Ming Peh, Choong-Tatt Ng, Tim Cushway, Fung-Joon Foo, Frederick Hong-Xiang Koh
This case series would like to highlight hypophosphatemia related to ferric carboxymaltose and its adverse clinical consequences.
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Trend in seroprevalence of HTLV-1/2 in Taiwanese blood donors—A 10-year follow-up Transfus. Med. (IF 1.5) Pub Date : 2023-05-20 Yu-Han Lee, Chi-Te Lu, I-Jung Feng, Chi-Ming Hung
This study evaluated the Human T-lymphotropic virus (HTLV) screening policy impact on the HTLV seroprevalence from 2009 to 2018 as well as the differences between administrative districts in terms of prevalence distribution in Taiwan.
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A multidisciplinary comparison of transfusion and perioperative support for high-risk cardiac surgery at three large academic centres in North America Transfus. Med. (IF 1.5) Pub Date : 2023-05-12 Jeremy W. Jacobs, Andrew W. Shih, Frederick W. Lombard, Justyna Bartoszko, Darren Mullane, Christine Cserti-Gadzewich, Quentin Eichbaum
Cardiac surgery is associated with numerous peri- and post-operative haemostatic complications and blood transfusion requirements. Complex procedures such as redo-sternotomy heart transplantation or type A aortic dissection repairs are at high-risk for severe coagulopathy and significant transfusion requirements. However, current practice guidelines do not specifically address high-risk surgeries,
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Hyperhaemolysis caused by anti-HI antibodies in a patient with myelodysplastic syndrome following a first ever red cell transfusion Transfus. Med. (IF 1.5) Pub Date : 2023-04-25 Richard Hinton, Ruby Haji, Richard Kaczmarski, Mark Layton, Akila Danga
Hyperhaemolysis is a rare and life-threatening delayed haemolytic transfusion reaction characterised by complement-mediated destruction of both host and transfused red cells. It is well recognised as a complication of transfusion in patients with haemoglobinopathies and has occasionally been described in haematological malignancy and anaemia of chronic disease. Anti-HI antibodies are usually clinically
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The lack of anti-PF4 antibodies in convalescent plasma from COVID-19 infected blood donor. Transfus. Med. (IF 1.5) Pub Date : 2023-03-30 Andrea Piccin,Barbara Mullin,Alastair Brown,Gary Benson
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Hemolytic disease of the newborn due to anti-Jra from a Chinese mother with one novel and one classic heterozygous mutation Transfus. Med. (IF 1.5) Pub Date : 2023-03-27 Jie Xiao, Qixiu Yang, Shouxi Gao, Hui Song, Fengyong Zhao, Zhonghui Guo, Yuyu Zhang, Ziyan Zhu, Luyi Ye, Dong Xiang
Investigation of a Jr(a-) family samples, identification of the mutant and assessment of the differences of Jr antigen density of the Jr(a-) family members, random adult and newborn individuals' RBCs.
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Prevalence and specificity of red blood cell antibodies in patients transfused in tertiary hospitals in Burkina Faso Transfus. Med. (IF 1.5) Pub Date : 2023-03-22 Salam Sawadogo, Koumpingnin Nébié, Catherine Traoré, Yérémadé Juste Bonzi, Mariam Boro, Dieudonné Yonli, Joseph Yaméogo, Paul Ouédraogo, Catherine Coulibaly, Jedida Zala, Véronique Deneys, Eléonore Kafando
Sub-Saharan African countries face the challenge of immunological transfusion safety that puts many patients at risk of post-transfusion hemolytic reactions. This is because pre-transfusion testing for irregular/unexpected antibodies that helps to prevent these risks are neither universally available nor accessible. The aim of our study was to determine the prevalence of red blood cell alloantibodies
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Optimising platelet usage during the induction therapy of acute myeloid leukaemia: Impact of physician education Transfus. Med. (IF 1.5) Pub Date : 2023-03-21 John Gnanaraj, Abhishekh Basavarajegowda, Smita Kayal, Dibyajyothi Sahoo, Esha Toora, Biswajit Dubashi, Prasanth Ganesan
Platelet products are scarce and expensive resources to be used judiciously. However, inappropriate usage is common. Lack of physician awareness is an important issue. We implemented a physician education program (PEP) along with repeated WhatsApp reminders at our centre. We audited the platelet usage practise before and after the intervention.
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The use of prothrombin complex concentrate in chronic liver disease: A review of the literature Transfus. Med. (IF 1.5) Pub Date : 2023-03-20 Marie-Astrid van Dievoet, Xavier Stephenne, Madeleine Rousseaux, Ton Lisman, Cedric Hermans, Véronique Deneys
Patients with chronic liver disease (CLD) and cirrhosis present a rebalanced hemostatic system in the three phases of haemostasis. This balance is however unstable and can easily tip towards bleeding or thrombosis. Management of both spontaneous bleeding and bleeding during invasive procedures remains a challenge in this patient population. Transfusion of blood products can result in circulatory overload
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Critical appraisal of knowledge, attitude and practice studies for blood donation in India Transfus. Med. (IF 1.5) Pub Date : 2023-03-20 Rahul Chaurasia, Gopal Kumar Patidar, Hem Chandra Pandey, Suganya Palanisamy, Lubna Naseer, Sapna Chopra, Vidushi Gupta
A critical appraisal of the literature helps to assess the strength and weakness of the research and suggests ways to improve future research. Our aim was to critically appraise the knowledge, attitude, and practice (KAP) studies conducted in India for blood donation.
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Cultured CD71+ erythroid cells modulate the host immune response Transfus. Med. (IF 1.5) Pub Date : 2023-03-15 Abdulrahman Alshalani, Boukje M. Beuger, Robin van Bruggen, Jason P. Acker, Nicole P. Juffermans
The study aimed to determine the impact of Red Blood Cells (RBCs) generated from peripheral blood mononuclear cells (PBMCs) on T cell proliferation and host response following whole blood stimulation.
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Emergency red cell exchange for the management of acute complications in sickle cell disease: Automated versus manual Transfus. Med. (IF 1.5) Pub Date : 2023-03-08 Diana Mihalca, Adeel Ahmad, Dipal Mehta, Tanya Freeman, Funmilayo Orebayo, Oloruntoyin Bello-Sanyaolu, Natasha Lewis, Basabi Chatterjee, Dimitris A. Tsitsikas
Red blood cell exchange is the cornerstone of the management for acute complications of sickle cell disease. It improves anaemia and improvesperipheral tissue oxygen delivery while at the same time reduces the proportion of circulating sickle erythrocytes. Even though automated red cell exchange is very effective in rapidly lowering the Hb S level, 24-h availability is currently not feasible for most
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Evaluation of two temperature storage conditions for full blood count samples from Lifeblood's donors Transfus. Med. (IF 1.5) Pub Date : 2023-03-02 Georgina Jacko, Anna Green, Leo Lycett, Sue Ismay, James Peberdy, James Daly
Lifeblood completes full blood count samples for selected donors to assess their suitability for future donations. Removing the current practice for refrigerated (2–8°C) storage and aligning with room temperature (20–24°C) storage of other donor blood samples would produce significant efficiencies in blood donor centres. This study aimed to compare full blood count results under two temperature conditions
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Hemolysis during therapeutic plasma exchange: A rare phenomena Transfus. Med. (IF 1.5) Pub Date : 2023-03-01 Brinda Kakkar, Sameer Melinkeri, Sharwari Narawade, Sanjiv Ketkar, Sonali Kulkarni
Hemolysis is an uncommon complication in patients undergoing therapeutic plasma exchange (TPE) using cell separator machine based on continuous centrifugation method. However, it is frequently encountered in patients undergoing TPE using a membrane filtration technique. We report an interesting case where hemolysis was noted during TPE using a cell separator machine.