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4D label-free proteome analysis of the liver damage mechanism in mice with chronic benzene exposure Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-09-16 Zhe Zheng, Hongwei Li, Zhenqian Zhang, Xiandun Zhai, Haojie Qin, Li Zhang
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A novel G3BP1-GFP reporter human kidney cell system enabling real-time monitoring of stress granule dynamics for in vitro kidney toxicity assessment Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-09-05 Hana Lee, Sunkyung Choi, Eun-Mi Kim, Kee K. Kim
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Ursolic acid inhibits autophagy-dependent neuronal cell death by reducing oxidative stress levels in an in vitro model of Parkinson’s disease Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-09-04 Jinyong Gao, BingHai Lei, Hui He, Di Xi, XiaoDong Wang, Chunhui Lian, Xiaoqin Sun, Zhitong Feng, Yanyan Yu
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Salvia microphylla essential oil reduces cell viability in cisplatin-resistant clear cell type ovarian cancer cells caused by mitochondrial dysfunction Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-08-27 Hyewon Jang, Hyeonmi Jo, Whasun Lim, Sunwoo Park, In Ho Choi
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HSP72 is a stimulus for activating toll-like receptor 2 in M2 macrophages leading to IL-6-mediated tumor malignancy Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-08-23 Wol Soon Jo, Min Ho Jeong, Soo Kyung Jeong, Su Jung Oh, Ji Sue Baik, Ji An Seo, Jeong-Hwa Baek, Chang Geun Lee, Joong Sun Kim, Sung Dae Kim, Moon-Taek Park
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Anti-inflammatory activity of Akebia quinata D. extracts by inhibiting MAPK and NF-κB signaling pathways in LPS-induced RAW 264.7 cells according to extraction solvents Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-08-03 Hyeon Mi Jo, In Ho Choi
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CircNFIX promotes stemness and evasion of phagocytosis in glioma stem cells by sponging miR-449a to upregulate the expression of CD47 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-24 Yuanwei Fu, Zhizhao Qu, Rui Bai, Liu Yang, Hongqin Wang
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Mangiferin can alleviate atopic dermatitis-like responses in mice and HaCaT cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-22 Cuilin Xie, MengYao Hu, Bin Niu
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Stress granule reporter system to assess perfluorooctanoic acid gastric toxicity in vitro Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-22 Jung-Min Lee, Kee K. Kim, Eun-Mi Kim
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Anti-melanogenic effects of porcine placenta peptides through inhibition of tyrosinase expression and activity Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-16 Wonchul Lim, Woo-Jin Sim, Kwang-Soo Baek, Jinhak Kim, Tae-Gyu Lim
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Desflurane restrains renal ischemia–reperfusion-stimulated endoplasmic reticulum stress and apoptosis via elevating microRNA-181c-5p to target DNA damage-inducible transcript 4 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-12 JunFu Liu, Hui Chen, Shiying Huang
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Zearalenone activates GnRH neurons related to central precocious puberty by regulating microRNA-384/GPER signaling Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-02 Yan Sun
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Silencing circRUFY1 protects retinal ganglion cell injury in acute intraocular hypertension by activating the ERK pathway through miR-196a-5p/CALM3 axis Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-07-02 BinBin Li, ShaoJun Li, Wei Tang, Min Zeng
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The therapeutic potential of Laggera alata in alleviating inflammation and oxidative stress: insights into the miR-150-5p/TRIM8 axis Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-24 JiangCun Wei, Sen Liang, Peng Yang, Bing Qing, JiaBao Ma, LeiMin Jiang, QingMei Deng, Wen Zhong, MingGang Wang, ZuJie Qin
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Nuclear translocation of β-catenin and migration of arecoline-induced oral cancer cells reduced by Taiwanin E via p-GSK3β downregulation Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-19 Chi-Cheng Li, Marthandam Asokan Shibu, Wei-Wen Kuo, Yueh-Hsiung Kuo, Yun-Peng Chao, Chun-Hsu Yao, Da-Tian Bau, Pei-Jei Lio, Chung-Jen Chiang, Chih-Yang Huang
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Hesperidin protects C2C12 myoblasts from oxidative damage by reducing ROS-mediated mitochondrial damage and endoplasmic reticulum stress Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-20 Yung Hyun Choi
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hsa_circ_0002454 controls cervical cancer cell growth and metastasis by targeting SDC4 through miR-654-3p Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-17 Yanmei Li, Yuzhen Zhang, Fuqiang Xu, Nan Wang, Qing Liu
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Long intergenic non-protein coding RNA 1436 accelerates cell proliferation, migration and adhesion properties of the MUM-2B cell line via microRNA-513a-5p/CUG Triplet repeat-binding protein 1 axis to activate the phosphatidylinositol 3-kinase/Akt signaling pathway Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-17 XinCheng Sun, ZhaoDong Chu, XiaoYan Zhao, MengJiao Wang, YaNan Kong, GuoHua Lu
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Clinical analysis of DNA methylation in the diagnosis of cervical lesions Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-14 Qin Tian, Huaxin Shi, Lihua Yang, Ting Guo, Hui Yang, Luying Zhu, Xuan long, Weina Wu, Jie Ren
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Unveiling the toxicological impact of yeast vacuoles in Daphnia Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-12 Taehwan Kim, Hyo Jin Choi, Woo-Ri Shin, Uyen Le Ngoc Phuong, Dae-Young Park, Ji-Young Ahn, Yang Hoon Kim, Jiho Min
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Intermittent caloric restriction effectively increases yeast chronological lifespan Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-09 Olumide Temitayo Jemiseye, Sung-Keun Lee
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Terrestrosin D inhibits invasion and induces apoptosis through inhibition of STAT3 in anaplastic thyroid carcinoma Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-06-03 Honglai Zhang, Dawei Sun, Peijie Lei, Jingjing Cheng
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Dietary flavonoids protect human brain microvascular endothelial cell from oxidative stress-induced dysfunction Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-30 Qian Tan, Xiaoqiong Yan, Lizhu Chen, Kun Jiang, Zhenli Guo
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Ursolic acid reverses hypoxia-driving radioresistance of glioma cells via SENP1/HIF‐1α axis Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-21 Bailin Zhang, Han Peng, Jing Zhang, Wenjin Wei, Jinshi Zhang, Xiaoqiang Pan, Qiuhua Jiang, Zhenyu Zhang
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Ethyl acetate layer of a methanol extract from Aquilaria crassna promotes oxidative stress-mediated apoptosis in non-small-cell lung cancer cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-16 Kwang-Youn Kim, You Lim Hwang, Kwang Il Park, Soon-Cheol Ahn
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FAM120A promotes angiogenesis in pancreatic cancer by increasing the mRNA expression of RHOA Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-16 Yifeng Wu, Jiye Feng, Chang Xin, Zongyang Wu, Minmin Cai, Wenyi Xu
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Plantamajoside ameliorates TGFβ2-induced autophagy, epithelial–mesenchymal transition and inflammatory processes in human lens epithelial cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-14 Xiaoxiang Sun, Xuequan Sun, Xinyan Xu, Yuxuan Wang, Susu Lu
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A preliminary study on the effects of Xiaoyao San on neurological function and 5-HT2A mRNA expression in mice with Tourette syndrome Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-13 Xingyue Liu, Guoyun Cao
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Liquiritin alleviates LPS-stimulated podocyte apoptosis and inflammation by activating Nrf2 signaling Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-14 Shijiao Zheng, Yu Li, Dan Luo, Cairong Zhu, Haiyan Zhao, Jing He, Hongyu Yang, Tong Wang, Zhen Chen
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Serum malondialdehyde and superoxide dismutase levels in patients with non-traumatic osteonecrosis of femoral head: a cross-sectional study Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-09 Wen-Xiu Zhu, Yong-Heng Zhao, Peng Zhang, Qing-He Ye, Biao-Fang Wei
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Cucurbitacin-I exhibits anticancer activity by inducing apoptosis in SKOV3 human ovarian cancer cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-06 Ji-Won Park, Seong Mi Kim, Soo Yeon Lee, Seung-Won Park, Jin-Kyung Kim
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Cytotoxicity-reducing and anti-inflammatory effects of a natural herb mixture extract Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-05-06 Jun-Ho Ahn, Sang-Hyun Shin, Se-Myo Park, Mi-Sun Choi, Soojin Kim, Jung-Hwa Oh, Seokjoo Yoon, Eun-Jung Park, Hyoung-Yun Han
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High expression of Testin predicted worse prognosis in pancreatic adenocarcinoma associated with immune infiltration Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-30 Rui Chen, Zhengli Zhou, Qihua Dang, Changjing Zuo, Tao Wang
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Oncheong-eum alleviated hepatic lipid accumulation and intestinal barrier disruption in nonalcoholic steatohepatitis in vivo model Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-29 Kwang-Youn Kim, Yun-Mi Kang, Tae In Kim, Yeon-Ji Kim, Kyungho Kim
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Unlocking the potential: Baicalin's apoptosis-reducing power and activation of NRF2/P62 for alleviating diabetic cardiomyopathy in rats Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-27 Wanling Wang, Rui Han, Li Lai, Xia Zhang
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Decreased LTBP2 expression inhibits proliferation and migration of glioma Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-26 Yonghui Zhang, Yue Qin, Xiaochen Yu
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Circ_0000277 promotes the malignant progression of oesophageal squamous cell carcinoma through miR-1294-dependent regulation of DVL3 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-22 Zejun Fu, Jiancheng Liu
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Toxicological implications of storage conditions on yeast vacuole properties and activities Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-22 Hyo Jin Choi, Taehwan Kim, Woo-Ri Shin, Jin-Pyo Lee, Uyen Le Ngoc Phuong, Ji-Young Ahn, Yang-Hoon Kim, Jiho Min
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Cobrotoxin, a single peptide from snake venom, ameliorates atopic dermatitis via suppression of MK2 modulated by IgE and IL-33 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-21 Jin Woo Lee, Younghoon Choi, Sang Heon Lee, No-June Park, Mediana Hadiwidjaja, Young Chang Sohn, Nurul Farhana Jufri, Eun-Hwa Sohn, Su-Nam Kim
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GPD1 relieves the proliferation, migration and invasion abilities of oral cancer cells by inhibiting mitochondrial function Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-19 Qichao Kang, Xiangling Liao, Zhen Du
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Molecular targets of histone deacetylase inhibitors in neurodegeneration and neuroprotection Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-17 Yeongwon Park, Shangfei Yu, Seung Yong Hwang, Hyemyung Seo
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New insight of exercise on dementia; combinatory effects of physical and cognitive exercise Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-13 Hyo-Jeong Cha, Jun Hong Park, Changwan Hong
Background Dementia is a progressive neurological disorder which is clinically characterized by memory loss, behavioral symptoms, and loss of ability to live a normal life. Dementia patients may have to cope with permanent and irreversible symptoms. Purpose of Review Although a new drug for dementia with beta-amyloid-removal function has recently received FDA approval, the effect of delaying the progression
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MicroRNA-29b-3p reduces cisplatin resistance in non-small cell lung cancer by targeting myeloid cell leukemia-1 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-12 Yuanjun Cheng, Bin Chen, Xuxiao Dong, Jian Shu, Jie Yao
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Licochalcone B, a natural anti-inflammatory agent, inhibits the inflammatory response and oxidative stress of periodontal ligament cells in periodontitis Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-07 Zhen Du, Xiangling Liao, Qichao Kang
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Tolylfluanid induces developmental toxicity via liver dysfunction in zebrafish embryos Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-02 Taeyeon Hong, Hahyun Park, Gwonhwa Song, Whasun Lim
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A novel immune-related LncRNA prognostic signature for cutaneous melanoma Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-04-01 Nan Hu, Cancan Huang, Yancheng He, Shuyang Li, Jingyi Yuan, Guishu Zhong, Yan Chen
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Establishment of a small-cell lung cancer (SCLC) mouse model using enhanced cancer stem-cell-functioning 3D SCLC spheroids Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-03-20 Yong Hun Jung, In Kyoung Kim, So Young Eom, Hyunsoo Kim, Kyungwon Park, Seok Chung, Sang Haak Lee, Chang Dong Yeo, Hye Joung Kim, Hye Seon Kang
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Cheong-sang-gyeon-tong-tang improves hepatic steatosis by regulating cholesterol metabolism Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-03-08 Yun-Mi Kang, Kwang-Youn Kim, Tae In Kim, Yeon-Ji Kim, Han-Hae Kim, Kyungho Kim
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Induction of glioblastoma invasion triggered by system Xc−-mediated glutamate release Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-03-07 Jiyoon Baik, Myunghoon Lee, Jae Hong Yoo, Ahyeon Jo, Kyung-Seok Han
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A systematic review of the carcinogenicity of rats and mice by sex due to exposure to phenyl compounds Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-03-05 Kyung-Taek Rim
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MicroRNA-34b-5p increases chemosensitivity of hepatocellular carcinoma cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-03-04 JinSuo Chen, LiNa Wang, XueMei Wu, ZhiJie Ding, WenXi Cao, LeiLei Yang, YongPing Zhou, Li Xia, Zhao Song
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Prediction of herb–drug interaction between hyperforin and sedative hypnotics (zolpidem, alprazolam, and midazolam) using physiologically-based pharmacokinetic modeling Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-24 Anna Shin, Boyun Jang, Sunyoung Cho, Youngsoo Kim, Min Soo Park, Kwang-Il Park, Young Woo Kim, Choon Ok Kim
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VD/VDR-mediated ATG16L1 activation reduces Alzheimer’s disease-like pathology and cognitive decline Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-24 Zhixiong Huang, Wei Ang, Hefei Huang, Yanyan Wang
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Dual suppressive effect of p-coumaric acid on pigmentation in B16F10 cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-22 Sohee Jang, Chang-Woo Ha, Sung-Hyeok Kim, Jung Hun Choi, Seung Namkoong, Sungsil Hong, Hyun Jung Koo, Youn-Kyu Kim, Mediana Hadiwidjaja, Sung Ryul Lee, Eun-Hwa Sohn
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Bergenin ameliorates the progression of atherosclerosis by inhibiting oxidative stress, inflammation, and monocytes adhesion in human umbilical vein endothelial cells Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-21 Liyuan Liang, Wei Yang
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Mechanistic insight of mitochondrial dysfunctions in cardiovascular diseases with potential biomarkers Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-20 Md. Nazmul Islam, Vineet Kumar Mishra, Rina Munalisa, Farzana Parveen, Saieeda Fabia Ali, Khadiza Akter, Tanvir Ahmed, Tsung-Jung Ho, Chih-Yang Huang
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The atypical protein kinase RIOK3 contributes to the phenotypic modulation of vascular smooth muscle cells in intracranial aneurysms Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-09 Jianzhu Wei, Yang Zhang, Bo Xie, Ziyi Zhu, Jingyu Qian, Yulin Tan
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Lycopene mitigates DHT-induced apoptosis and oxidative stress in human granulosa cell line KGN by regulating the Nrf2 pathway Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-05 Yue Chen, Mengmeng Zhao, Xiaoqing Li, Yuanyuan Liu, Yuhong Shang
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CARD9 regulates myocardial inflammation, oxidative stress, and vascular dysfunction in hypertensive rats by activating MAPK/p38 pathway in combination with NOD2 Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-02-01 XiangBin Xin, Jing Zhang, YanQin Du, XiaoTing Jang, XinYi Tian, Fu Ma, Fang Chen
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Evaluation of the antinociceptive effect and standardization of Platycladus orientalis (L.) Franco extract Mol. Cell. Toxicol. (IF 1.1) Pub Date : 2024-01-26 Hyun-Yong Kim, Guanglei Zuo, Hee Jung Lee, Seung Hwan Hwang, Soo Kyeong Lee, Jun Hong Park, Hong-Won Suh, Soon Sung Lim