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A Narrative Review of Strategies to Optimize Nutrition, Feeding, and Growth among Preterm-born Infants: Implications for Practice. Adv. Nutr. (IF 8.0) Pub Date : 2024-09-21 Faith E Bala,Katlyn E McGrattan,Christina J Valentine,Sudarshan R Jadcherla
Preterm birth is the leading cause of neonatal and under-five mortality globally, and healthcare-related burden and nutrition-related morbidities are unsustainable, particularly among resource-limited regions. Additionally, preterm infants are susceptible to multiple adverse outcomes including growth faltering, sub-optimal neurodevelopment, and multi-systemic morbidities. Maturation, healing, repair
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Effects of Nonnutritive Sweeteners on the BMI of Children and Adolescents: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Prospective Cohort Studies Adv. Nutr. (IF 8.0) Pub Date : 2024-09-13 Alan Espinosa, Kenny Mendoza, Hugo Laviada-Molina, Jorge Aarón Rangel-Méndez, Fernanda Molina-Segui, Qi Sun, Deirdre K. Tobias, Walter C. Willett, Josiemer Mattei
The effect of nonnutritive sweeteners (NNSs) on the body mass index [BMI (in kg/m2)] of children and adolescents remains unclear despite rising consumption. Detailed systematic evaluations are warranted. We aimed to summarize evidence on NNS consumption and BMI sex- and age-specific absolute changes (kg/m2) in pediatric populations, by NNS type, study design, duration, analysis type, conflicts of interest
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Exploring Multidimensional and Within-Food Group Diversity for Diet Quality and Long-Term Health in High-Income Countries Adv. Nutr. (IF 8.0) Pub Date : 2024-09-03 Anaëlle Bolo, Eric Verger, Hélène Fouillet, François Mariotti
Dietary diversity is a crucial component of healthy eating patterns because it ensures nutritional adequacy. Yet, concerns have been raised about the potential risks of its increase, which may reflect excessive consumption of unhealthy foods and higher obesity or cardiometabolic risk, particularly in high-income countries. However, the links between dietary diversity and different health outcomes remain
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The Effect of Whole-Diet Interventions on Memory and Cognitive Function in Healthy Older Adults – A Systematic Review Adv. Nutr. (IF 8.0) Pub Date : 2024-08-19 Lina Tingö, Cecilia Bergh, Julia Rode, Maria Fernanda Roca Rubio, Jonas Persson, Linnea Brengesjö Johnson, Lotte H Smit, Ashley N Hutchinson
An increasing number of cross-sectional studies suggests that diet may impact memory and cognition in healthy older adults. However, randomized controlled trials investigating the effects of whole-diet interventions on memory and cognition in healthy older adults are rather rare, and conflicting results are often reported. Therefore, a systematic review was conducted to compile the current evidence
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Emerging Evidence and Critical Issues with the Use of Single-Drop Capillary Blood for the Measurement of Hemoglobin Concentration in Population-Level Anemia Surveys Adv. Nutr. (IF 8.0) Pub Date : 2024-08-14 Crystal D Karakochuk, Omar Dary, Monica C Flores-Urrutia, Maria Nieves Garcia-Casal, Chika Hayashi, Maria Elena D Jefferds, Robert Johnston, Leila M Larson, Carine Mapango, Dora I Mazariegos Cordero, Denish Moorthy, Sorrel Namaste, Lisa M Rogers, Kuntal Saha, Sara Wuehler
Accurate and precise measurement of hemoglobin concentration is critical for reliable estimations of anemia prevalence at the population level. When systematic and/or random error are introduced in hemoglobin measurement, estimates of anemia prevalence might be significantly erroneous and, hence, limit their usefulness. For decades, single-drop capillary blood has been the most common blood source
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Evolution of Dietary Diversity: Further Consideration of Contextual and Multidimensional Features Adv. Nutr. (IF 8.0) Pub Date : 2024-08-13 Kirsten A Herrick, Jennifer L Lerman
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Recommendations for Designing, Conducting, and Reporting Feeding Trials in Nutrition Research Adv. Nutr. (IF 8.0) Pub Date : 2024-08-10 Delyse SY Tien, Meghan Hockey, Daniel So, Jordan Stanford, Erin D Clarke, Clare E Collins, Heidi M Staudacher
Double-blind, placebo-controlled, randomized controlled trials are the gold standard for clinical trials in nutrition science. For trials of whole diets, dietary counseling is advantageous as they offer clinical translatability although can vary in the fidelity of the intended intervention from participant to participant and across studies. Feeding trials, in which most or all food is provided, offer
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An Overview of Reviews on the Association of Low Calorie Sweetener Consumption With Body Weight and Adiposity Adv. Nutr. (IF 8.0) Pub Date : 2024-08-08 Kelly A Higgins, Rita Rawal, Matthew Kramer, David J Baer, Aaron Yerke, David M Klurfeld
Numerous systematic reviews (SR) and meta-analyses (MA) on low calorie sweeteners (LCS) have been published in recent years, concluding that LCS have beneficial, neutral, or detrimental effects on various health outcomes, depending on the review. The objective of this overview of reviews was to determine how the methodologies of SR investigating the association between LCS consumption and body weight
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Prevalence of and Survival with Cachexia among Patients with Cancer: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-08-08 Tomoya Takaoka, Akinori Yaegashi, Daiki Watanabe
Cachexia is associated with lower overall survival (OS) in patients with cancer; however, the relationship between the two is reported to differ according to the definitive criteria for diagnosing cachexia.
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The Carbon Isotope Ratio as an Objective Biomarker of Added Sugar Intake: A Scoping Review of Current Evidence in Human Nutrition Adv. Nutr. (IF 8.0) Pub Date : 2024-07-31 Gina L Tripicchio, Alissa D Smethers, Jessica J Johnson, Jordan A Olenginski, Diane M O’Brien, Jennifer Orlet Fisher, Vitalina A Robinson, Sarah H Nash
Objective biomarkers of dietary intake are needed to advance nutrition research. The carbon isotope ratio (C13/C12; CIR) holds promise as an objective biomarker of added sugar (AS) and sugar-sweetened beverage (SSB) intake. This systematic scoping review presents the current evidence on CIRs from human studies. Search results (through April 12, 2024) yielded 6297 studies and 24 final articles. Studies
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We Are What, When, And How We Eat: The Evolutionary Impact of Dietary Shifts on Physical and Cognitive Development, Health, and Disease Adv. Nutr. (IF 8.0) Pub Date : 2024-07-25 Nicola Luigi Bragazzi, Daniele Del Rio, Emeran A Mayer, Pedro Mena
“We are what, when, and how we eat”: the evolution of human dietary habits mirrors the evolution of humans themselves. Key developments in human history, such as the advent of stone tool technology, the shift to a meat-based diet, control of fire, advancements in cooking and fermentation techniques, and the domestication of plants and animals, have significantly influenced human anatomical, physiological
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Disrupted Prenatal Metabolism May Explain the Etiology of Suboptimal Neurodevelopment: A Focus on Phthalates and Micronutrients and their Relationship to Autism Spectrum Disorder Adv. Nutr. (IF 8.0) Pub Date : 2024-07-24 Mariana Parenti, Carolyn M Slupsky
Pregnancy is a time of high metabolic coordination, as maternal metabolism adapts to support the growing fetus. Many of these changes are coordinated by the placenta, a critical fetal endocrine organ and the site of maternal–fetal crosstalk. Dysregulation in maternal and placental metabolism during pregnancy has been linked to adverse outcomes, including altered neurodevelopment. Autism spectrum disorder
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Nutritional Modulation of Host Defense Peptide Synthesis: A Novel Host-Directed Antimicrobial Therapeutic Strategy? Adv. Nutr. (IF 8.0) Pub Date : 2024-07-23 Melanie Whitmore, Isabel Tobin, Amanda Burkardt, Guolong Zhang
The escalating threat of antimicrobial resistance underscores the imperative for innovative therapeutic strategies. Host defense peptides (HDPs), integral components of innate immunity, exhibit profound antimicrobial and immunomodulatory properties. Various dietary compounds, such as short-chain fatty acids, vitamins, minerals, sugars, amino acids, phytochemicals, bile acids, probiotics, and prebiotics
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Health Effects of Various Edible Vegetable Oils: An Umbrella Review Adv. Nutr. (IF 8.0) Pub Date : 2024-07-23 Phooi Tee Voon, Choon Ming Ng, Yen Teng Ng, Yen Jun Wong, Sia Yen Yap, Siew Lian Leong, Xiou Shuang Yong, Shaun Wen Huey Lee
Vegetable oils, derived from diverse sources such as seeds, nuts, and some fruits, play a significant role in dietary health. However, the current evidence on the health effects of different types of vegetable oil consumption remains controversial. This umbrella review aims to synthesize evidence from systematic reviews and meta-analyses to assess the health outcomes associated with various vegetable
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Analytic Methods for Understanding the Temporal Patterning of Dietary and 24-H Movement Behaviors: A Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-07-18 Rebecca M Leech, Stephanie E Chappel, Nicola D Ridgers, Heather A Eicher-Miller, Ralph Maddison, Sarah A McNaughton
Dietary and movement behaviors [physical activity (PA), sedentary behavior (SED), and sleep] occur throughout a 24-h day and involve multiple contexts. Understanding the temporal patterning of these 24-h behaviors and their contextual determinants is key to determining their combined effect on health. A scoping review was conducted to identify novel analytic methods for determining temporal behavior
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Intersections of Climate Change with Food Systems, Nutrition, and Health: An Overview and Evidence Map Adv. Nutr. (IF 8.0) Pub Date : 2024-07-15 Thalia Morrow Sparling, Claudia Offner, Megan Deeney, Philippa Denton, Kristin Bash, Rachel Juel, Susan Moore, Suneetha Kadiyala
Scientific research linking climate change to food systems, nutrition, and nutrition-related health (FSNH) has proliferated, showing bidirectional and compounding dependencies that create cascading risks for human and planetary health. Within this proliferation, it is unclear which evidence to prioritize for action and which research gaps, if filled, would catalyze the most impact. We systematically
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Antioxidants and Fertility in Women with Ovarian Aging: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-07-15 Yujie Shang, Nannan Song, Ruohan He, Minghua Wu
Ovarian aging is a major factor for female subfertility. Multiple antioxidants have been applied in different clinical scenarios, but their effects on fertility in women with ovarian aging are still unclear. To address this, a meta-analysis was performed to evaluate the effectiveness and safety of antioxidants on fertility in women with ovarian aging. A total of 20 randomized clinical trials with 2617
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Magnesium and Cognitive Health in Adults: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-07-14 Fan Chen, Jifan Wang, Yijie Cheng, Ruogu Li, Yifei Wang, Yutong Chen, Tammy Scott, Katherine L Tucker
Magnesium (Mg) plays a key role in neurological functioning and manifestations. However, the evidence from randomized controlled trials (RCTs) and cohorts on Mg and cognitive health among adults has not been systematically reviewed. We aimed to examine the associations of various Mg forms (supplements, dietary intake, and biomarkers) with cognitive outcomes by summarizing evidence from RCTs and cohorts
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Is There Evidence to Support Probiotic Use for Healthy People? Adv. Nutr. (IF 8.0) Pub Date : 2024-07-06 Daniel J Merenstein, Daniel J Tancredi, J Philip Karl, Alex H Krist, Irene Lenoir-Wijnkoop, Gregor Reid, Stefan Roos, Hania Szajewska, Mary Ellen Sanders
Probiotics are typically marketed as foods and dietary supplements, categories for products intended to maintain health in generally healthy populations and which, unlike drugs, cannot claim to treat or cure disease. This review addresses the existing evidence that probiotics are beneficial to healthy people. Our approach was to perform a descriptive review of efficacy evidence that probiotics can
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Artificial Intelligence in Malnutrition: A Systematic Literature Review Adv. Nutr. (IF 8.0) Pub Date : 2024-07-04 Sander MW Janssen, Yamine Bouzembrak, Bedir Tekinerdogan
Malnutrition among the population of the world is a frequent yet underdiagnosed problem in both children and adults. Development of malnutrition screening and diagnostic tools for early detection of malnutrition is necessary to prevent long-term complications to patients’ health and well-being. Most of these tools are based on predefined questionnaires and consensus guidelines. The use of artificial
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Dietary Patterns in Asia: Current Evidence and Future Directions Adv. Nutr. (IF 8.0) Pub Date : 2024-06-20 Lukas Schwingshackl, Georg Hoffmann
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Dietary Patterns and Cardiovascular Diseases in Asia: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-06-20 Gladys Huiyun Lim, Nithya Neelakantan, Yu Qi Lee, Su Hyun Park, Zhi Heng Kor, Rob M van Dam, Mary Foong-Fong Chong, Airu Chia
With emerging Asian-derived diet quality indices and data-driven dietary patterns available, we aimed to synthesize the various dietary patterns and quantify its association with cardiovascular diseases (CVDs) among Asian populations. We systematically searched PubMed, Embase, Scopus, and Web of Science for observational studies in South, Southeast, and East Asia. Dietary patterns were grouped “high-quality
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Galacto-Oligosaccharides and the Elderly Gut: Implications for Immune Restoration and Health Adv. Nutr. (IF 8.0) Pub Date : 2024-06-17 Yunan Hu, Mashael R Aljumaah, Maria Andrea Azcarate-Peril
The increasing prevalence of noncommunicable diseases in the aging population has been correlated with a decline in innate and adaptive immune responses; hence, it is imperative to identify approaches to improve immune function, prevent related disorders, and reduce or treat age-associated health complications. Prebiotic supplementation is a promising approach to modulate the gut microbiome and immune
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The Effect of Time-Restricted Eating Combined with Exercise on Body Composition and Metabolic Health: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-06-17 Zihan Dai, Kewen Wan, Masashi Miyashita, Robin Sze-tak Ho, Chen Zheng, Eric Tsz-chun Poon, Stephen Heung-sang Wong
Time-restricted eating (TRE) is increasingly popular, but its benefits in combination with exercise still need to be determined. This systematic review and meta-analysis aimed to evaluate the efficacy of TRE combined with exercise compared with control diet with exercise in improving the body composition and metabolic health of adults. Five electronic databases were searched for relevant studies. Randomized
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A Systematic Review and Bayesian Network Meta-Analysis Comparing In-Person, Remote, and Blended Interventions in Physical Activity, Diet, Education, and Behavioral Modification on Gestational Weight Gain among Overweight or Obese Pregnant Individuals Adv. Nutr. (IF 8.0) Pub Date : 2024-06-13 Hongli Yu, Mingmao Li, Guoping Qian, Shuqi Yue, Zbigniew Ossowski, Anna Szumilewicz
Despite the well-documented adverse outcomes associated with obesity during pregnancy, this condition remains a promising modifiable risk factor. The aim of this study was to ascertain the most effective treatment modalities for gestational weight gain (GWG) in pregnant women classified as overweight or obese. A systematic search was conducted across 4 electronic databases: Embase, EBSCOhost, PubMed
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The Quality of Lunches Brought from Home to School: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-06-12 Siwan Song, Elizabeth Tabares, Ariun Ishdorj, Molly Crews, Jayna Dave
This systematic review and meta-analysis, spanning studies published between 1995 and 2021, investigates various aspects of lunches brought from home (LBFH) to school by children. These meals, in contrast to those provided by the National School Lunch Program (NSLP), lack strict nutritional standards. Despite the availability of NSLP lunches, ∼40% of US children opt for LBFH. This review aims to assess
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National Policies to Limit Food Marketing and Competitive Food Sales in Schools: A Global Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-06-12 Michelle Perry, Kayla Mardin, Grace Chamberlin, Emily A Busey, Lindsey Smith Taillie, Francesca R Dillman Carpentier, Barry M Popkin
School food environments contribute to children’s nutritional intake and overall health. As such, the World Health Organization and other public health organizations encourage policies that restrict children’s access and exposure to foods and beverages that do not build health in and around schools. This global scoping review explores the presence and characteristics of policies that restrict competitive
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Ceramides as Emerging Players in Cardiovascular Disease: Focus on Their Pathogenetic Effects and Regulation by Diet Adv. Nutr. (IF 8.0) Pub Date : 2024-06-12 Riccardo Spaggiari, Sharon Angelini, Alessandra Di Vincenzo, Gerarda Scaglione, Sara Morrone, Veronica Finello, Sofia Fagioli, Fabiola Castaldo, Juana M Sanz, Domenico Sergi, Angelina Passaro
Impaired lipid metabolism is a pivotal driver of cardiovascular disease (CVD). In this regard, the accumulation of ceramides within the circulation as well as in metabolically active tissues and atherosclerotic plaques is a direct consequence of derailed lipid metabolism. Ceramides may be at the nexus between impaired lipid metabolism and CVD. Indeed, although on one hand ceramides have been implicated
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Time to Step-Up Our Game Concerning Nutrient Analysis of Pasteurized Donor Human Milk? Adv. Nutr. (IF 8.0) Pub Date : 2024-05-30 Deborah L O’Connor
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Impact of Holder Pasteurization and Preanalytical Handling Techniques on Fat Concentration in Donor Human Milk: A Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-05-30 Autumn Davis, Maryanne T Perrin
Donor human milk (DHM) is an essential source of nutrition among high-risk infants (e.g., premature and low-birth weight). Holder pasteurization, a common step in DHM processing, is known to partially alter the composition of DHM; however, the impact on fat composition is historically inconsistent. This scoping review aimed to broadly review the literature on the impact of Holder pasteurization on
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Mitigating Intestinal Dysbiosis in the Very Preterm Infant Adv. Nutr. (IF 8.0) Pub Date : 2024-05-20 Mark A Underwood
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Effects of Probiotics on Preterm Infant Gut Microbiota Across Populations: A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-05-20 Pandi He, Leilei Yu, Fengwei Tian, Wei Chen, Hao Zhang, Qixiao Zhai
Microbiota in early life is closely associated with the health of infants, especially premature ones. Probiotics are important drivers of gut microbiota development in preterm infants; however, there is no consensus regarding the characteristics of specific microbiota in preterm infants receiving probiotics. In this study, we performed a meta-analysis of 5 microbiome data sets (1816 stool samples from
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New Feature: Student and Trainee-Focused Podcast Interviews with Article Authors Adv. Nutr. (IF 8.0) Pub Date : 2024-05-17 Steven A Abrams
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Different Roles of Tocopherols and Tocotrienols in Chemoprevention and Treatment of Prostate Cancer Adv. Nutr. (IF 8.0) Pub Date : 2024-05-10 Qing Jiang
The vitamin E family contains α-tocopherol (αT), βT, γT, and δT and α-tocotrienol (TE), βTE, γTE, and δTE. Research has revealed distinct roles of these vitamin E forms in prostate cancer (PCa). The ATBC trial showed that αT at a modest dose significantly decreased PCa mortality among heavy smokers. However, other randomized controlled trials including the Selenium and Vitamin E Cancer Prevention Trial
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Human MicroRNAs Modulated by Diet: A Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-05-10 Gwen M Chodur, Francene M Steinberg
Because of their role in regulating and fine-tuning gene expression in the posttranscriptional period, microRNA (miRNA) may represent a mediating factor that connects diet and metabolic regulation. Given the vast number of miRNAs and that modulations in miRNA happen in response to a variety of stimuli, a comprehensive registry of miRNAs impacted by diet and the food items that modulate them, would
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Effects of Iron Status on Adaptive Immunity and Vaccine Efficacy: A Review Adv. Nutr. (IF 8.0) Pub Date : 2024-05-08 Nicole U. Stoffel, Hal Drakesmith
Vaccines can prevent infectious diseases, but their efficacy varies, and factors impacting vaccine effectiveness remain unclear. Iron deficiency is the most common nutrient deficiency, affecting >2 billion individuals. It is particularly common in areas with high infectious disease burden and in groups that are routinely vaccinated, such as infants, pregnant women, and the elderly. Recent evidence
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Prioritizing Nutrition in Medical Education—the Time Has Come Adv. Nutr. (IF 8.0) Pub Date : 2024-05-07 Andrew A Bremer
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The Extent, Range, and Nature of Quantitative Nutrition Research Engaging with Intersectional Inequalities: A Systematic Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-05-04 Emily Fivian, Helen Harris-Fry, Claudia Offner, Michele Zaman, Bhavani Shankar, Elizabeth Allen, Suneetha Kadiyala
Addressing malnutrition for all requires understanding inequalities in nutrition outcomes and how they intersect. Intersectionality is increasingly used as a theoretical tool for understanding how social characteristics intersect to shape inequalities in health outcomes. However, little is known about the extent, range, and nature of quantitative nutrition research engaging with intersectional inequalities
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Revolutionizing Neonatal Nutrition: Rethinking Definitions and Standards for Optimal Care Adv. Nutr. (IF 8.0) Pub Date : 2024-04-26 Ariel A Salas
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There and Back Again: A Forty-Year Perspective on Physician Nutrition Education Adv. Nutr. (IF 8.0) Pub Date : 2024-04-24 Jaclyn Lewis Albin, Olivia W Thomas, Farshad Fani Marvasti, Jo Marie Reilly
Medical education faces an urgent need for evidence-based physician nutrition education. Since the publication of the 1985 National Academies report “Nutrition Education in the United States Medical Schools,” little has changed. Although several key efforts sought to increase nutrition content in undergraduate medical education over the past 40 y, most medical schools still fail to include the recommended
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Expected and Desirable Preterm and Small Infant Growth Patterns Adv. Nutr. (IF 8.0) Pub Date : 2024-04-24 Tanis R Fenton, Stephanie Merlino Barr, Seham Elmrayed, Belal Alshaikh
Adequate nutrition is necessary for achieving optimal growth and neurodevelopment. Growth is a natural and expected process that happens concomitantly with rapid advancements in neurodevelopment. Serial weight, length, and head circumference growth measures are essential for monitoring development, although identifying pathological deviations from normal growth can pose challenges. Appropriate growth
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Effects of (Poly)phenols on Circadian Clock Gene–Mediated Metabolic Homeostasis in Cultured Mammalian Cells: A Scoping Review Adv. Nutr. (IF 8.0) Pub Date : 2024-04-20 Noha Sulaimani, Michael J Houghton, Maxine P Bonham, Gary Williamson
Circadian clocks regulate metabolic homeostasis. Disruption to our circadian clocks, by lifestyle behaviors such as timing of eating and sleeping, has been linked to increased rates of metabolic disorders. There is now considerable evidence that selected dietary (poly)phenols, including flavonoids, phenolic acids and tannins, may modulate metabolic and circadian processes. This review evaluates the
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Is Maternal Body Weight or Composition Associated with Onset of Lactogenesis II, Human Milk Production, or Infant Consumption of Mother’s Own Milk? A Systematic Review and Meta-Analysis Adv. Nutr. (IF 8.0) Pub Date : 2024-04-11 Amanda V Montana, Alison Mildon, Allison I Daniel, Michael A Pitino, Jo-Anna B Baxter, Megan R Beggs, Sharon L Unger, Deborah L O’Connor, Kathryn Walton
Maternal adiposity impacts lactation performance, but the pathways are unclear. We conducted a systematic review to understand whether maternal adiposity (body mass index [BMI] or percentage fat mass) is associated with onset of lactogenesis II (copious milk; hours), human milk production (expressed volume/24 h), and infant consumption of mother’s own milk (volume/24 h). We used random-effects standard
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Perspective: Beyond the Mediterranean Diet—Exploring Latin American, Asian, and African Heritage Diets as Cultural Models of Healthy Eating Adv. Nutr. (IF 8.0) Pub Date : 2024-04-09 Kelly E LeBlanc, Sara Baer-Sinnott, Kristie J Lancaster, Hannia Campos, Ka Hei Karen Lau, Katherine L Tucker, Lawrence H Kushi, Walter C Willett
The Mediterranean diet is a well-studied cultural model of healthy eating, yet research on healthy models from other cultures and cuisines has been limited. This perspective article summarizes the components of traditional Latin American, Asian, and African heritage diets, their association with diet quality and markers of health, and implications for nutrition programs and policy. Though these diets
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Diet, Food, and Nutritional Exposures and Inflammatory Bowel Disease or Progression of Disease: an Umbrella Review Adv. Nutr. (IF 8.0) Pub Date : 2024-04-08 Camilla Christensen, Andrea Knudsen, Erik K Arnesen, Jan Gunnar Hatlebakk, Ida Sofie Sletten, Lars T Fadnes
Inflammatory bowel disease (IBD), including Crohn’s disease (CD) and ulcerative colitis (UC), contributes to substantial morbidity. Understanding the intricate interplay between dietary factors and the incidence and progression of IBD is essential for developing effective preventative and therapeutic strategies. This umbrella review comprehensively synthesizes evidence from systematic reviews and meta-analyses
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Human Milk Oligosaccharides and Respiratory Syncytial Virus Infection in Infants Adv. Nutr. (IF 8.0) Pub Date : 2024-04-05 Karina M Tonon, Somchai Chutipongtanate, Ardythe L Morrow, David S Newburg
In infants worldwide, respiratory syncytial virus (RSV) is the leading cause of lower respiratory infections, including bronchiolitis, which is a major source of infant mortality. Bronchiolitis is the most common lower respiratory infection and the major cause of hospitalization in the first 6 mo of life. Infant responses to RSV infection are highly diverse, with symptoms varying from asymptomatic
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Infant Formulas With Partially or Extensively Hydrolyzed Milk Proteins for the Prevention of Allergic Diseases: A Systematic Review and Meta-Analysis of Clinical Trials Adv. Nutr. (IF 8.0) Pub Date : 2024-04-04 Xiaoxu Li, Tingchao He, Sufang Duan, Jinghong Liang, Gang Feng, Fang Li, Zhenyu Shen, Wenhui Ye, Biao Liu, Bibo Jiang, Yujing Chen, Nan Liu, Ignatius Man-Yau Szeto, Li Cai
Despite the widely recommended usage of partially hydrolyzed formula (PHF) or extensively hydrolyzed formula (EHF) of milk protein for preventing allergic diseases (ADs), clinical studies have been inconclusive regarding their efficacy compared with that of cow's milk formula (CMF) or breast milk (BM). We aimed to systematically evaluate the effects of PHF or EHF compared with those of CMF or BM on
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Effect of Antioxidant Supplementation on Macular Pigment Optical Density and Visual Functions: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials Adv. Nutr. (IF 8.0) Pub Date : 2024-04-04 Weili Hu, Vernice Seah, Vanessa Huang, Jung Eun Kim
Antioxidants are bioactive molecules that function to scavenge free radicals and balance oxidative stress. Although all antioxidants can act as reactive oxygen species scavengers, their efficacy on eye health may vary. Moreover, the comparative effectiveness and potential additive effect between groups of antioxidants, hitherto, have not been systematically studied. A systematic review and network
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Nutritional Strategies for Managing Iron Deficiency in Adolescents: Approaches to a Challenging but Common Problem Adv. Nutr. (IF 8.0) Pub Date : 2024-03-29 Clay T Cohen, Jacquelyn M Powers
Iron deficiency (ID) is a common and challenging problem in adolescence. In order to prevent, recognize, and treat ID in this age range, it is critical to understand the recommended daily intake of iron in relation to an adolescent’s activity, dietary habits, and basal iron losses. Adolescents following vegetarian or vegan diets exclusively rely on plant-based, nonheme iron, which has decreased bioavailability
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Reply to J Barbaresko et al. Adv. Nutr. (IF 8.0) Pub Date : 2024-03-28 Marilena Vitale, Rosalba Giacco
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Uncovering Shortcomings and Deficiencies in the Systematic Review and Meta-Analysis on Ultraprocessed Food Consumption and Human Health Adv. Nutr. (IF 8.0) Pub Date : 2024-03-28 Janett Barbaresko, Alexander Lang, Sabrina Schlesinger
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Understanding and Intervening in Nutrition-Related Health Disparities Adv. Nutr. (IF 8.0) Pub Date : 2024-03-21 Maninder Kahlon
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Perspective: Nutrition Health Disparities Framework: A Model to Advance Health Equity Adv. Nutr. (IF 8.0) Pub Date : 2024-03-21 Tanya Agurs-Collins, Jennifer Alvidrez, Sanae ElShourbagy Ferreira, Mary Evans, Kimberlea Gibbs, Bramaramba Kowtha, Charlotte Pratt, Jill Reedy, Marissa Shams-White, Alison GM Brown
Disparities in nutrition, such as poor diet quality and inadequate nutrient intake, arise from multiple factors and are related to adverse health outcomes such as obesity, diabetes, cardiovascular disease, and some cancers. The aim of the current perspective is to present a nutrition-centric socioecological framework that delineates determinants and factors that contribute to diet and nutrition-related
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Observational Dose-Response Meta-Analysis Methods May Bias Risk Estimates at Low Consumption Levels: The Case of Meat and Colorectal Cancer Adv. Nutr. (IF 8.0) Pub Date : 2024-03-21 Jane G Pouzou, Francisco J Zagmutt
Observational studies of foods and health are susceptible to bias, particularly from confounding between diet and other lifestyle factors. Common methods for deriving dose-response meta-analysis (DRMA) may contribute to biased or overly certain risk estimates. We used DRMA models to evaluate the empirical evidence for colorectal cancer (CRC) association with unprocessed red meat (RM) and processed
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Perspective: The Place of Pork Meat in Sustainable Healthy Diets Adv. Nutr. (IF 8.0) Pub Date : 2024-03-18 Adam Drewnowski
The food systems sustainability framework has 4 domains: nutrition, economics, environment, and society. To qualify as sustainable, individual foods and total diets need to be nutrient-rich, affordable, environmentally friendly, and socially acceptable. Pork is the most consumed meat globally, providing high-quality protein and several priority micronutrients. With research attention focused on plant-based
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Quantifying Overlapping Forms of Malnutrition Across Latin America: A Systematic Literature Review and Meta-Analysis of Prevalence Estimates Adv. Nutr. (IF 8.0) Pub Date : 2024-03-15 Diana Sagastume, Antonio Barrenechea-Pulache, Andrea Ruiz-Alejos, Katja Polman, Lenka Beňová, Manuel Ramírez-Zea, José L Peñalvo
Estimating the prevalence of double burden of malnutrition (DBM) is challenging in the Latin American and Caribbean (LAC) region where various DBM typologies (e.g., obesity and stunting) are heterogeneous and estimates are scattered across literature This study aimed to assess the prevalence of DBM typologies in the LAC region. We searched PubMed, Embase, Scopus, and Web of Science to identify studies