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Global hotspots and trends in Acanthosis nigricans research: A bibliometric and visualized analysis Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-11 Shaobo Zhang, Huixin Yan, Weichen Sun, Jingnan Li, Jing Xu, Di Cao, Bailin Song, Xingquan Wu
BackgroundAcanthosis nigricans (AN) is a common skin disease characterized by clear pigmented patches on the folds of the skin. However, the AN research field lacks scientific and comprehensive bibliometric analysis. This article aims to use bibliometric methods to summarize and visualize the distribution patterns, research hotspots, and development trends of AN literature.MethodsLiterature from 1900
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Amelanotic melanoma of the nail unit: Clinical and dermoscopic features of the nail plate changes Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-11 Emi Dika, Pier Alessandro Fanti, Carlotta Baraldi, Federico Venturi, Biagio Scotti, Giulia Veronesi, Laura Miccio, Sabina Vaccari
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Clinical effects of polynucleotide with hyaluronic acid intradermal injections on facial erythema: Effective redness treatment using polynucleotides Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-11 Dongkeun Kenneth Lee, Myungjune Oh, Michael James Kim, Seung Min Oh
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A comparison of several separation processes for eggshell membrane powder as a natural biomaterial for skin regeneration Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-11 Samaneh Esmaeili, Majid Rahmati, Sepehr Zamani, Ali R. Djalilian, Zohreh Arabpour, Majid Salehi
BackgroundNumerous studies have focused on skin damage, the most prevalent physical injury, aiming to improve wound healing. The exploration of biomaterials, specifically eggshell membranes (ESMs), is undertaken to accelerate the recovery of skin injuries. The membrane must be separated from the shell to make this biomaterial usable. Hence, this investigation aimed to identify more about the methods
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Effective use of skin microbiome signatures for fingerprint identification Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-11 Seda Salman Yılmaz, Mert Ahmet Kuşkucu, Hüseyin Çakan, Gökhan Aygün
BackgroundRecent advances have increased the importance of the human microbiome, including the skin microbiome. Despite the hand microbiome research, the factors affecting the composition of the hand microbiome and their personal characteristics are incompletely known.ObjectivesDespite changing environmental factors and personal variation, we aimed to indicate the interpersonal distinction between
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Proanthocyanidins alleviate Henoch‐Schönlein purpura by mitigating inflammation and oxidative stress through regulation of the TLR4/MyD88/NF‐κB pathway Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-10 Xiaolong Li, Meng Wang, Shihong Pan, Li Xian, Shuyi Zhang, Dehai Xian, Jianqiao Zhong
ObjectiveInvestigate Proanthocyanidins (PCs) efficacy and mechanisms in treating Henoch‐Schönlein purpura (HSP)‐like rat models, focusing on inflammatory and oxidative stress (OS) responses.MethodsAn HSP‐like rat model was established using ovalbumin (OVA) injection, leading to symptoms mimicking HSP. The study measured inflammatory markers (IL‐4, IL‐17, TNF‐α), OS markers (MDA, SOD, CAT), and assessed
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A bibliometric and visual analysis of the research status and hotspots of seborrheic dermatitis based on web of science Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-10 Huixin Yan, Shaobo Zhang, Weichen Sun, Jingnan Li, Jing Xu, Yunpeng Bi, Xingquan Wu, Bailin Song
BackgroundSeborrheic dermatitis (SD) is a common chronic inflammatory skin disease. In recent years, significant progress has been made in the field of SD, but there has been no bibliometric research yet. This study aims to use bibliometric methods to analyze the current research status and hot topics of SD, to understand further the research trends and future development prospects in this field.MethodsRetrieve
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Correction to “Analysis of factors influencing the recurrence of diabetic foot ulcers ” Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-10
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Mechanism of Zuogui pill enhancing ovarian function and skin elastic repair in premature aging rats based on artificial intelligence medical image analysis Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-09 Xinpei Zhang, Fuju Wang, Xiaodan Zhu, Lan Xu, Ling Qin, Wenjuan Xu, Bozhen Fan
BackgroundAI medical image analysis shows potential applications in research on premature aging and skin. The purpose of this study was to explore the mechanism of the Zuogui pill based on artificial intelligence medical image analysis on ovarian function enhancement and skin elasticity repair in rats with premature aging.Materials and MethodsThe premature aging rat model was established by using an
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Cosmeceuticals in photoaging: A review Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-05 Lisa Kwin Wah Chan, Kar Wai Alvin Lee, Cheuk Hung Lee, Kar Wai Phoebe Lam, Kar Fai Victor Lee, Raymond Wu, Jovian Wan, Shanthala Shivananjappa, Wong Tin Hau Sky, Hosung Choi, Kyu‐Ho Yi
BackgroundPhotoaging is a process of the architecture of normal skin damaged by ultraviolet radiation. Topical cosmeceuticals have been used to treat this condition. The authors aimed to understand the mechanism and level of evidence of different commonly used cosmeceuticals used to treat photodamaged skin.ObjectiveA range of commonly used topical cosmeceuticals (botanicals, peptides, and hydroquinone)
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Emerging trends and research hotspots in the relationship between mast cells and atopic dermatitis based on the literature from 2001 to 2024: A bibliometric and visualized analysis Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-05 Wen Zuo, Zhang Yue, Shuang Xu, Cai‐Hong Sun, Xiong‐Fei Zou, Jie Ma, Han Yan, Xiao‐Wen Gu, Ming‐Yan Wang
BackgroundAtopic dermatitis (AD) is a prevalent chronic inflammatory and highly pruritic skin condition characterized by the infiltration of immune cells, notably eosinophils and mast cells. Mast cells (MCs) critically participate in the complex pathogenesis of AD through multiple pathways and have recently garnered growing attention in research. Despite the abundance of related studies published over
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Assessment of current practices and perceived effectiveness of injectable polynucleotide for enlarged facial pores among cosmetic physicians: A survey‐based evaluation Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-05 Dagyeong Lee, Hosung Choi, Kyounghun Yoo, Young Jin Park, Hyun Jun Park, Seung Min Oh, Gun Hyon Ji, Gong Chan Rah, Dong Wook Shin
BackgroundPolynucleotides stimulate collagen formation and are used clinically to enhance elasticity. In this study, we investigated current practices and perceived effectiveness of polynucleotide injection treatment for enlarged facial pores among cosmetic physicians.Materials and MethodsA survey was developed to investigate clinicians’ use and effectiveness of polynucleotides in the treatment of
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Quantitative interpretation of infrared images of lower limbs in individuals with and without type 2 diabetes mellitus Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-05 Edgar I. Fuentes‐Oliver, Rosalinda Ortiz‐Sosa, Raúl Serrano‐Loyola, Rebeca Solalinde‐Vargas, Crescencio García‐Segundo
BackgroundThe quantitative interpretation of the radiometric information extracted from infrared (IR) images in individuals with and without type 2 diabetes mellitus (DM2) is an open problem yet to be solved. This is of particular value given that DM2 is a worldwide health problem and onset for evolution toward diabetic foot disease (DFD). Since DM2 causes changes at the vascular and neurological levels
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Diagnostic value for methylation in cervical cancer based on a small‐molecule fluorescent probe targeting DNMT1 Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-05 Baohua Yang, Chao Xu, Hang Li, Xiuxiang Zhu, Ziyin Xia, Ling Xu, Qian Zhang
BackgroundValue analysis of a small‐molecule fluorescent probe for methylation detection in different cervical lesions.Materials and Methods(1) The grayscale values of distinct lesion tissues were remarkably distinct among the four groups (p < 0.05). The comparison of the grayscale value between the two groups showed that the CA group noticeably exceeded the LSIL and cervicitis groups, and the HSIL
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Comparing 3D imaging devices for the measurement of cutaneous neurofibromas in patients with Neurofibromatosis Type 1 Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-03 Jonathan C. L. Lau, Jane Fleming, Martin Good, Adrian Lim, Rebecca B. Saunderson, Tai A. Phan, Timothy Schlub, Sue‐Faye Siow, Nanette Lacson, Carlos Romo, Jaishri Blakely, Christina Bergqvist, Yemima D. Berman
BackgroundCutaneous neurofibromas (cNFs) are a major cause of disfigurement in patients with Neurofibromatosis Type 1 (NF1). However, clinical trials investigating cNF treatments lack standardised outcome measures to objectively evaluate changes in cNF size and appearance. 3D imaging has been proposed as an objective standardised outcome measure however various systems exist with different features
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A case of superficial CD34‐positive fibroblastic tumor on the axilla of an 11‐year‐old girl Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Siting Zheng, Jipeng Liu, Sha Zhou
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Comparison of facial skin ageing in healthy Asian and Caucasian females quantified by in vivo line‐field confocal optical coherence tomography 3D imaging Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Assi Ali, Lopez Colombe, Pedrazzani Mélanie, Pignol‐Lavoix Agnes, Nili Meryem, Ralambondrainy Samuel, Grignon Guénolé, Cauchard Jean‐Hubert, Korichi Rodolphe, Bonnier Franck
BackgroundQuantitative biomarkers of facial skin aging were investigated in 109 healthy Asian female volunteers, aged 20 to 70 years.Materials and MethodsIn vivo 3D Line‐field Confocal Optical Coherence Tomography (LC‐OCT) imaging, enhanced by Artificial Intelligence (AI)‐based quantification algorithms, was utilized to compute various metrics, including stratum corneum thickness (SC), viable epidermal
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Effect of umbilical cord mesenchymal stem cell‐derived mitochondrial transplantation on ischemia‐reperfusion injury in a rat model Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Chan Yeong Lee, Galina Khan, Dong Yun Hyun, Sang Hun Kim, Eun Soo Park
BackgroundDespite advancements in reconstructive procedures, ischemia‐reperfusion (I/R) injury remains a significant challenge in reconstructive surgery, with mitochondrial dysfunction playing a pivotal role. Mitochondrial transplantation has emerged as a promising therapeutic strategy to address this issue. This study aims to evaluate the impact of umbilical cord mesenchymal stem cell‐derived mitochondrial
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A novel Skin lesion prediction and classification technique: ViT‐GradCAM Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Muhammad Shafiq, Kapil Aggarwal, Jagannathan Jayachandran, Gayathri Srinivasan, Rajasekhar Boddu, Adugna Alemayehu
BackgroundSkin cancer is one of the highly occurring diseases in human life. Early detection and treatment are the prime and necessary points to reduce the malignancy of infections. Deep learning techniques are supplementary tools to assist clinical experts in detecting and localizing skin lesions. Vision transformers (ViT) based on image segmentation classification using multiple classes provide fairly
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The diagnostic value and associated molecular mechanism study for fibroblast‐related mitochondrial genes on keloid Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Ting Wei, Zuojiao Xu
PurposeThis study aims to reveal the mechanism of fibroblast‐related mitochondrial genes on keloid formation and explore promising signature genes for keloid diagnosis.MethodThe distribution of fibroblasts between the keloid sample and control sample based on three keloid datasets, followed by the differentially expressed genes (DEGs) investigation and associated enrichment analysis. Then, hub genes
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Targeted precision cryotherapy for acne vulgaris Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Ji Yeon Hong, Ka Ram Kim, Hyun Jung Kim, Joon Seok, Kui Young Park
BackgroundAcne vulgaris poses a significant dermatological challenge, necessitating alternative treatments due to limitations and side effects associated with current therapies. This pilot clinical trial investigated the feasibility and efficacy of precision cryotherapy for acne vulgaris.MethodsA total of 20 volunteers underwent targeted precision cryotherapy using a carbon dioxide‐based device. Treatment
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Investigating the efficacy of Endolift laser and Nanofat as a combination therapy for horizontal neck lines compared to Nanofat autologous alone Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Mohammad Ali Nilforoushzadeh, Shohreh Rafiee, Maryam Heidari‐Kharaji, Tannaz Fakhim, Niloufar Najar Nobari, Mohammadhasan Shahverdi, Zahra Lotfi, Sona Zare, Elham Torkamaniha, Shiva Alavi
BackgroundThe emergence of horizontal neck wrinkles is increasingly becoming a focal point for both cosmetic professionals and clients. Various treatment approaches must be considered to address this issue effectively, owing to its diverse underlying causes. The study explores the potential of utilizing the Endolift laser in conjunction with nanofat injection as a viable treatment option.MethodsTwenty
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Skin microbiome and causal relationships in three dermatological diseases: Evidence from Mendelian randomization and Bayesian weighting Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Xiaojian Li, Shiyu Chen, Shupeng Chen, Shiping Cheng, Hongrong Lan, Yunbo Wu, Guirong Qiu, Lingjin Zhang
BackgroundAtopic dermatitis (AD), psoriasis (PSO), rosacea, and other related immune skin diseases are affected by multiple complex factors such as genetic and microbial components. This research investigates the causal relationships between specific skin microbiota and these diseases by using Mendelian randomization (MR), and Bayesian weighted Mendelian randomization (BWMR).MethodsWe utilized genome‐wide
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Evaluation of hair surface structure and morphology of patients with lichen planopilaris (LPP) by atomic force microscopy (AFM) Skin Res. Technol. (IF 2.0) Pub Date : 2024-09-02 Karolina Krawczyk‐Wołoszyn, Magdalena Żychowska, Adam Reich
BackgroundLichen planopilaris (LPP) is a chronic lymphocytic skin disease manifested by progressive scarring alopecia. The diagnosis of LPP is made based on histopathological examination, although it is not always definite. The current study evaluates the effectiveness of non‐invasive atomic force microscopy (AFM) hair examination in detecting morphological differences between healthy and diseased
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Effect of sequential delivery of 1‐ and 2‐MHz bipolar microneedling radiofrequency energy on thermal tissue reactions in a minipig model Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-30 Sung Bin Cho, Sun Young Kang, Yea‐Jin Lee, Min Choi, Bora Kim, Jin‐Chul Ahn
BackgroundBipolar microneedling radiofrequency (RF) treatment generates different patterns of thermal reactions, depending on the skin impedance and RF treatment parameters, including the frequency, power, conduction time, settings of sub‐pulse packs, and penetrating depth and type of microneedles used. We compared the effect of sequential delivery of 1‐ and 2‐MHz bipolar RF energy to in vivo minipig
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Artificial intelligence in psychodermatology: A brief report of applications and impact in clinical practice Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-29 Isabella J. Tan, Olivia M. Katamanin, Rachel K. Greene, Mohammad Jafferany
BackgroundThis report evaluates the potential of artificial intelligence (AI) in psychodermatology, emphasizing its ability to enhance diagnostic accuracy, treatment efficacy, and personalized care. Psychodermatology, which explores the connection between mental health and skin disorders, stands to benefit from AI's advanced data analysis and pattern recognition capabilities.Materials and methodsA
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High‐powered 675‐nm laser: Safety and efficacy in clinical evaluation and in vitro evidence for different skin disorders Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-29 Massimo D. F. Vitale, Francesca Madeddu, Irene Fusco, Laura Pieri, Paolo Bonan, Tiziano Zingoni, Giada Magni, Francesca Rossi
BackgroundLaser technology is a viable therapeutic option for treating a number of skin pathologic conditions, including pigmented lesions, vascular lesions and acne scars.AimIn this work, through in vitro and clinical investigations we test the efficacy, the safety and the speed of treatment of high‐powered laser system emitting a 675‐nm in the management of various skin condition.Materials and methodsIn
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A comparison of the safety and efficacy of tapinarof and roflumilast topical therapies in the management of mild‐to‐moderate plaque psoriasis Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-29 Hira Ghani, Alicia Podwojniak, Isabella J. Tan, Aarushi K. Parikh, Bianca Sanabria, Babar Rao
IntroductionPsoriasis is an immune‐mediated inflammatory skin disease. First‐line topical treatments include steroids, calcineurin inhibitors, vitamin D analogs, and anthralin. Recently, novel topical therapeutics like tapinarof and roflumilast have emerged with unique anti‐inflammatory mechanisms and promising efficacy profiles.Materials and methodsThis review utilized PubMed, SCOPUS, and Web of Science
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The causal relationship between immune cells and atopic dermatitis: A bidirectional Mendelian randomization study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-28 Xu Zhu, Wenzhong Wu
BackgroundAtopic dermatitis (AD) is a chronic inflammatory skin condition whose origins remain unclear. Existing epidemiological evidence suggests that inflammation and immune factors play pivotal roles in the onset and progression of AD. However, previous research on the connection between immune inflammation and AD has yielded inconclusive results.MethodsTo evaluate the causal relationship between
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Evaluating psychodynamic therapy for nail picking and biting: An approach to body focused repetitive behaviors Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-27 Isabella J. Tan, Priya Agarwal, Stacy K. Nakell, Mohammad Jafferany
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Recent advances in artificial intelligent strategies for tissue engineering and regenerative medicine Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-27 Maliheh Gharibshahian, Mohammad Torkashvand, Mahya Bavisi, Niloofar Aldaghi, Akram Alizadeh
BackgroundTissue engineering and regenerative medicine (TERM) aim to repair or replace damaged or lost tissues or organs due to accidents, diseases, or aging, by applying different sciences. For this purpose, an essential part of TERM is the designing, manufacturing, and evaluating of scaffolds, cells, tissues, and organs. Artificial intelligence (AI) or the intelligence of machines or software can
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Arsenical keratosis in China: A case report and review of the literature Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-27 Rong Tao, Ruojun Wang
BackgroundArsenical keratosis is a precancerous dermatosis which could be induced by long‐term exposure to arsenic poisoning. Arsenic is often added to traditional Chinese medicine in a non‐compliant manner to increase the effectiveness of psoriasis treatment, which is often the main cause of arsenic poisoning in Chinese patients with psoriasis.ObjectivesWe performed a systemic review of arsenic keratosis
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Low dose oral minoxidil for the treatment of female pattern hair loss Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-26 Paul Gressenberger, Daisy Kopera
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Glow or No‐Go: Ethical considerations of adolescent and teen skincare trends in social media Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-26 Aarushi K. Parikh, Shari R. Lipner
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Safety and efficacy of Deucravacitinib for moderate to severe plaque psoriasis: A meta‐analysis Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-24 Caixia Hu, Xiaomei Han, Yu Cui, Yan Zhang, Yi Cheng
BackgroundTo systematically evaluate the safety and efficacy of Deucravacitinib for moderate to severe plaque psoriasis.Materials and MethodsRandomized controlled trials (RCTs) of Deucravacitinib for moderate to severe plaque psoriasis in PubMed, Cochrane Library, Embase, and Web of Science were searched from database establishment to April 2023. Literature quality was independently evaluated by two
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Musical note flap repair large defects of the proximal nail fold: A case report Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-24 Renheng Zhu, Shuqiong Huang, Dingbin Yang
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Effectiveness of platelet‐rich plasma in treating female hair loss: A systematic review and meta‐analysis of randomized controlled trials Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-23 Jing Yuan, Yimin He, Hui Wan, Ying Gao
BackgroundHair loss profoundly affects women's physical appearance and psychological health. Platelet‐rich plasma (PRP) therapy has gained attention as a potential treatment for female hair loss. This systematic review and meta‐analysis aim to evaluate the efficacy and safety of PRP in treating different forms of female hair loss.MethodsA comprehensive search was conducted across PubMed, EMBASE, Scopus
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Co‐regulatory mechanisms and potential markers of oxidative stress‐related genes in vitiligo and alopecia areata Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-23 Chao Sun, Honghua Ding, Li Zhang, Junling Wang, Mengyun Su
BackgroundThe specific role of oxidative stress (OS) in vitiligo and alopecia areata (AA) remains unclear. The aim of this study was to analyze and identify the key markers of OS in vitiligo and AA by bioinformatics.MethodsWe obtained vitiligo and AA datasets from gene expression omnibus (GEO) database. The difference‐expressed genes of vitiligo and AA were identified by differential analysis, and
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Skin iconography analysis of traumatic anserine folliculosis: Skin image feature of TAF Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-23 Yuantao Song, Meixiang Rong, Qinfeng Li
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Neutrophil extracellular trap related risk score exhibits crucial prognostic value in skin cutaneous melanoma, associating with distinct immune characteristics Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Haiyang Zhang, Xiaoqing Bi, Pengrong Yan, Congcong Wang
BackgroundNeutrophil extracellular traps (NETs) are related to the prognosis of cancer patients. Nevertheless, the potential prognostic values of NETs in skin cutaneous melanoma (SKCM) remains largely unknown.Materials and methodsThe NET‐related gene signature was constructed by LASSO Cox regression analysis using the TCGA‐SKCM cohort. The overall survival (OS) and immune status in SKCM patients between
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Cover Image Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Bee Leng LUA, Linda RUAN, Ying LYU, Simon LIU
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In vitro efficacy of Rosa damascena solid state fermentation liquid and water extract on skin care Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Zhixiong Chen, Ni Hong, Nuo Xu, Cui Yan, Ping Cao, Hong Yao
BackgroundAs a medicinal and food homologous plant, Rosa damascena is not only highly ornamental, but also rich in a variety of active ingredients such as polyphenols and flavonoids. It is widely used in cosmetics, food and pharmaceutical industries.ObjectiveTo study the in vitro efficacy of Rosa damascena solid state fermentation liquid (RDF) and water extract (RDE).MethodsFirstly, the effect of RDF
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Mechanism of action of montmorillonite powder on injury and repair factors in Stage II pressure ulcers in model mice Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Xiaofei Li, Jinying Zhao
BackgroundThis study aims to elucidate the therapeutic effects and underlying mechanisms of montmorillonite powder on wound healing in mice with Stage II pressure ulcers, thereby providing a robust foundation for its clinical application in the treatment of such ulcers.Materials and methodsSixty 8‐week‐old specific pathogen‐free male BALB/c mice were randomly allocated into three groups: a model group
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A bibliometric analysis of global research on microbial immune microenvironment in melanoma from 2012 to 2022 Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Lin Sun, Jianghui Ying, Rong Guo, Lingling Jia, Hongyi Zhang
BackgroundMelanoma is an aggressive malignancy primarily impacting the skin, mucous membranes, and pigment epithelium. The tumor microbial microenvironment encompasses both the microorganisms inhabiting the tumor vicinity and the environmental factors influencing their interactions. Emerging evidence highlights the pivotal role of the microbial immune microenvironment in melanoma.MethodsWe conducted
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Adipose‐derived stem cells transplantation improves survival and alleviates contraction of skin grafts via promoting macrophages M2 polarization Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Yuying Cui, Jiahao He, Zheyuan Yu, Sizheng Zhou, Dejun Cao, Taoran Jiang, Bin Fang, Guangshuai Li
BackgroundFull‐thickness skin grafts are widely used in plastic and reconstructive surgery. The main limitation of skin grafting is the poor textural durability and associated contracture, which often needs further corrective surgery. Excessive inflammation is the main reason for skin graft contractions, which involve overactivation of myofibroblasts. These problems have prompted the development of
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Association of partial infections with the risk of psoriasis: A two‐sample Mendelian randomization study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Minghui Lu, Changyong Gao, Runtian Zhang, Lingling Yuan, Xi Chen, Boping Zhang
BackgroundAs a common chronic recurrent inflammatory skin disease, psoriasis is characterized by erythema and scaly skin lesions, with infection as an integral part of the pathogenesis of many diseases. Many previous cases reported the impact of psoriasis on infection. However, the existing research fails to completely clarify the infection factors associated with the potential of these diseases and
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Time‐dependent change of T cell receptor clonality: From large plaque parapsoriasis to early mycosis fungoides Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Munenari Itoh, Akihiko Asahina, Yoshimasa Nobeyama
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LC‐OCT as a tool to visualize in vivo location of dermal fillers Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Noah Musolff, Bianca Sanabria, Victoria Caetano, Laura Pulgarin, Zaima Sohail Chaudhry, Babar Rao
BackgroundDermal fillers have emerged as a popular non‐surgical solution for facial rejuvenation and enhancement. Apart from botulinum toxin injections, they are the most common non‐surgical procedure performed in the US. Line‐field optical coherence tomography (LC‐OCT; deepLive system Damae Medical, France) represents one of the most recent developments in non‐invasive skin imaging technologies.Materials
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A faster CO2 fractional scanner system mode for skin rejuvenation. A clinical study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Domenico Piccolo, Tiziano Zingoni, Irene Fusco, Francesca Madeddu, Claudio Conforti
BackgroundThe market requires ever‐faster techniques, in particular for pre‐rejuvenation condition.AimThe purpose of this study was to assess if a fractional CO2 scanner modality (called moveo) results in a faster full‐face rejuvenation treatment in comparison to the standard mode, currently existing in the scanner system.Materials and MethodsA total of 12 female patients affected by fine lines participated
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Helicobacter pylori infection in psoriatic patients and its relation to psoriasis severity: Cross Sectional Study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Soheir Abdel‐Hamid, Shimaa Arafat Abdel‐Monem
BackgroundPsoriasis is a prevalent inflammatory skin condition that can be recognized by silvery‐white scales on plaques and erythematous papules, despite the fact that psoriasis appears to have multiple causes. Helicobacter pylori (H. pylori) has been investigated recently as a potential infectious etiological component.AimsThe objective of the study was to evaluate the prevalence of H. pylori infection
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Orbital myositis induced by botulinum toxin injection: A case report Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Joe Khodeir, Paul Ohanian
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The gut‐facial aging axis: A two‐sample Mendelian randomization and mediation analysis of gut microbiota, gut microbiota metabolic pathways, and blood metabolites Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-22 Sha Yang, Ying Zhao, Jian Liu, Jianning Song, Qingyan Long, Si Cheng
BackgroundFacial aging (FA) is a complex process influenced by both genetic and environmental factors. Gut microbiota (GM), gut microbiota metabolic pathways (GMMPs), and blood metabolites (BMs) have been implicated in the regulation of FA, but the causal and mediating effects of these factors remain unclear.MethodsWe used summary‐level data from genome‐wide association studies (GWAS) of 16S rRNA gene
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Rutin alleviates psoriasis‐related inflammation in keratinocytes by regulating the JAK2/STAT3 signaling Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-21 Panhong Wu, Yonghui Liu, Hanxue Zhai, Xiaohan Wu, Aimin Liu
BackgroundPsoriasis is a chronic inflammatory skin disease that can cause systemic inflammation in various organs. Rutin has been suggested to fight psoriasis, but the signaling pathways by which it works need to be explored.Materials and methodsHaCaT cells co‐stimulated with interleukin (IL)‐17, IL‐22, tumor necrosis factor‐alpha (TNF‐α), IL‐1α, and oncostatin M (M5) were used as an in vitro cell
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Epidermal and dermal hydration in relation to skin color parameters Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-21 Harvey N. Mayrovitz, Kawaiola Aoki, Emily Deehan, Marissa Ruppe
BackgroundOur goal was to investigate linkages between skin color parameters and skin hydration. Since most prior studies focused on stratum corneum hydration, we focused on epidermal and dermal hydration in relation to skin color parameters in both sexes.Materials and MethodsThirty adults (16 female) with an age ± SD of 24.3 ± 0.6 years participated. Three sites on both volar forearms were evaluated
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Development of alginate/chitosan hydrogel loaded with obestatin and evaluation of collagen type I, III, VEGF and TGF‐β1 gene expression for skin repair in a rat model (in vitro and in vitro study) Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-21 Nazanin Toumaj, Majid Salehi, Sepehr Zamani, Zohreh Arabpour, Ali R. Djalian, Majid Rahmati
BackgroundSkin injuries have long been recognized as a prevalent type of physical injury. As a result, numerous research studies have been performed to discover an effective mechanism for wound healing. Therefore, tissue engineering of skin has developed as a potential solution for traditional methods of treating skin injuries.Methods and materialsAlginate/Chitosan hydrogel was mixed with 1, 10, 100
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Improvement of self‐administration experience with a new injection device: Real‐life experience with risankizumab in patients with psoriasis Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-20 Alexandra Maria Giovanna Brunasso, Ilaria Salvi, Stefania Sorbara, Andrea Muracchioli, Elena De Col, Manuela Baldari, Aurora Parodi, Emanuele Cozzani, Martina Burlando
BackgroundTrypanophobia or “needle phobia” represents a potential hindrance to the effective management of chronic diseases whenever an injectable therapy might be required, especially in case of frequent administrations. Psoriasis, a chronic dermatologic disease, can be effectively treated with biologic drugs administered subcutaneously. Thankfully, anti‐IL‐23 drugs require few administrations per
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Causal association of micronutrients and supplements with pressure ulcer: A Mendelian randomization study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-16 Yanting Huang, Song Shang, Haiyang Du
BackgroundPressure ulcer (PU) is known to be associated with abnormalities of micronutrient status. However, to date, it is not clear whether a causal relationship exists between circulating levels of micronutrients and their supplementations and PU.MethodsA two‐sample Mendelian randomization (MR) study was conducted using summary statistics from Genome‐Wide Association Studies (GWAS). Genetic instrumental
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The causal relationships of granulocytes and melanoma skin cancer: A univariable and multivariable Mendelian randomization study Skin Res. Technol. (IF 2.0) Pub Date : 2024-08-16 Zhang Rui‐chang, Peng Hui‐zi, Zhou Lin
BackgroundIncreasing evidence has revealed that granulocyte has a critical role in tumorigenesis and progression. In this study, Mendelian randomization (MR) analysis was utilized for estimating the causal association between neutrophil percentage and melanoma skin cancer, eosinophil percentage and melanoma skin cancer, basophil percentage and melanoma skin cancer, respectively.MethodsThe Genome‐Wide