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Abdominal obesity and CKD: A potential mediating role of serum metabolites in the UK Biobank population. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-09-16 Hanwen Ye,Hafiz Muhammad Yasir,Jinbo Hu,Wenjin Luo,Yao Qin,Lina Mao,Zhuo Chen,Xiaoru Zhang,Qifu Li,Xiangjun Chen,Zhihong Wang
BACKGROUND It is generally known that although a connection between abdominal obesity and chronic kidney disease (CKD) is well-established, there is a lack of systematic research investigating the specific roles of serum metabolites, including lipid metabolites, amino acid metabolites, carbohydrate metabolites and inflammatory substances in explaining this associations. METHODS We included 118,020
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Association between body mass index and sex hormones among men: Evidence from cross-sectional and Mendelian randomization studies. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-09-03 Junhao Chen,Zilin Wang,Yi Zhou,Zhien Zhou,Weigang Yan
PURPOSE This study aims to investigate the association between Body Mass Index (BMI) and sex hormone levels utilizing a cross-sectional study design alongside Mendelian randomization (MR) analysis. MATERIALS AND METHODS A cross-sectional study was performed based on National Health and Nutrition Examination Survey (NHANES) 2013-2016. Additionally, a two-sample MR analysis was performed, utilizing Single
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Letter to the editor: Incidence of type 2 diabetes after gastric by-pass surgery in a Swedish controlled cohort study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-08-31 Shabee ul Hassan
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Weight loss trends in Korean adolescents (2005-2021): Exploring the impact of measured and self-perceived weight status. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-08-27 Kayoung Lee
OBJECTIVE This study aims to assess the trends in the proportions of weight loss efforts among Korean adolescents aged 10-18 years from 2005 to 2021, examining variations based on weight status, to examine factors related to weight loss efforts by weight status, and to evaluate weight loss efforts based on the combination of measured and self-perceived weight status. METHODS Complex sample design analyses
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Characteristics of the epicardial adipose tissue measured by low-dose chest computed tomography according to the metabolic health/obesity status. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-08-22 Bo Da Nam,Soon Hyo Kwon,Byung-Won Park,Seong Soon Kwon
BACKGROUND Epicardial adipose tissue (EAT) is associated with the development of cardiovascular disease and long-term survival. This study aimed to assess the characteristics of EAT according to the metabolic health and obesity status using low-dose chest computed tomography (CT). METHODS A total of 1074 asymptomatic adults who underwent a medical health check-up were enrolled. Subjects were categorized
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Single point insulin sensitivity estimator index for identifying metabolic syndrome in US adults: NHANES 2017-march 2020. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-08-12 Wonhee Cho,Myong-Won Seo,Jared Rosenberg,Joon Young Kim
PURPOSE Single Point Insulin Sensitivity Estimator (SPISE) index was recently introduced as a reliable indirect indicator of insulin resistance, applicable to large population-based research. Here, we aimed to 1) examine racial/ethnic differences in SPISE index among US adults, 2) compare predictive power of SPISE index for metabolic syndrome (MetSyn) by race/ethnicity, and 3) evaluate its predictive
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Lipidomics reveals ceramide biomarkers for detecting central precocious puberty in girls. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-08-09 Ngan Thi Kim Nguyen,Shih-Yi Huang,Hsien-Yu Fan,Te-Hsuan Tung,Quynh Thi Vu Huynh,Chen Yang,Yang Ching Chen
BACKGROUND Pubertal timing is modulated by complex interactions between the pituitary and gonadal sex steroid hormones. Evidence indicates that sphingolipids are involved in the biosynthesis of steroid hormones at multiple levels. METHOD This study recruited adolescent female patients from pubertal and pediatric endocrine clinics in Northern and Southern Taiwan from the Taiwan Puberty Longitudinal
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Possible pitfalls in the prediction of weight gain in middle-aged normal-weight individuals: Results from the NDB-K7Ps-study-2. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-30 Kei Nakajima,Airi Sekine,Ryoko Higuchi,Mai Enokido,Sadako Matsui
BACKGROUND The prevalence of obesity has not decreased worldwide and obesity-related morbidities have been increasing steadily. However, few studies have investigated factors contributing to weight gain in normal-weight individuals. Thus, in this community-based cohort study, we aimed to investigate factors contributing to weight gain in normal-weight participants. METHODS Clinical variables and 10
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A convenient calf proportion index calculator for survival prediction in overweight and obese patients with cancer. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-25 Jia-Xin Huang,Xi Zhang,Wen-Jie Zhu,Meng Tang,Chun-Hua Song,Jiu-Wei Cui,Min Yang,Cong Zhao,Chao Wang,Han-Ping Shi,Ming-Hua Cong
OBJECTIVE This study aimed to define the calf proportion index (CPI) and investigate its association with malnutrition and survival in overweight and obese patients with cancer. METHODS This multicenter observational cohort study included 3499 patients diagnosed with cancer, including 3145 overweight and 354 obese individuals. The CPI was defined as the ratio of the cross-sectional area of the calf
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Evidence for central obesity risk-related thresholds for adolescents aged 11 to 18 years in England using the LMS method. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-16 Laura A Gray
INTRODUCTION Central obesity has been shown to better indicate health risks compared to general obesity. Measures of central obesity include waist-to-height ratio (WHtR), waist-to-hip ratio (WHR) and waist circumference (WC). The National Institute of Health and Care Excellence (NICE) recently recommended the use of WHtR alongside body mass index (BMI) to identify risks in adults and children, whilst
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Investigation of setmelanotide, an MC4R agonist, for obesity in individuals with Smith-Magenis syndrome. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-09 Julia Lazareva,Stephanie R Sisley,Sheila M Brady,Ann C M Smith,Sarah H Elsea,Jeremy J Pomeroy,Christian L Roth,Jennifer E Sprague,Martin Wabitsch,Jill Garrison,Jack A Yanovski
BACKGROUND Smith Magenis Syndrome (SMS) is a rare genetic disorder caused by RAI1 haploinsufficiency. Obesity in people with SMS is believed partially due to dysfunction of the proximal melanocortin 4 receptor (MC4R) pathway. We therefore studied effects of treatment with the MC4R agonist setmelanotide on obesity and hunger, as well as metabolic, cardiac and safety, in individuals with SMS. METHODS
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Diurnal rythm of Nampt is gender and weight dependent Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-03 I.V. Frielitz-Wagner, J. Mattutat, F.S. Frielitz, K. Scheuermann, J. Gesing, D. Marheineke, D. Löffler, W. Kiess, A. Körner
Nicotinamide phosphoribosyltransferase (Nampt) is an adipocytokine that is elevated in obesity, type 2 diabetes and increased levels are associated with inflammatory processes. Nampt serum concentrations have been suggested to follow a diurnal rhythm peaking in the afternoon in lean males. However, no data exists regarding the effects of gender and body weight. We measured Nampt serum levels over 24 h
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Cardio-metabolic health effects of CPAP treatment for sleep apnoea during weight loss: A randomised controlled pilot trial Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-02 Camilla M. Hoyos, Elizabeth A. Machan, Brendon J. Yee, Svetlana Postnova, Nathaniel S. Marshall, Tania Markovic, Stephen M. Twigg, Ronald R. Grunstein, Craig L. Phillips
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30-day morbidity and mortality of revisional bariatric surgery – An international multi-centre collaborative (BROAD) study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-07-01 Amrit Manik Nasta, Ramen Goel, Rishi Singhal, Luc Lemmens, Sarfaraz Baig, Yosuke Seki, Arun Prasad, Sonja Chiappetta, Mohammad Kermansaravi, Marc Vertruyen, Beniamino Pascotto, Juan Santiago Azagra, Waleed Al-Khyatt, Gennaro Martines, Diva Y Villao, Leandro Revello, Marco Rioseco, Francesco Martini, Arnaud Liagre, Gildas Juglard, Giovanni Dapri, Monika A Proczko-Stepaniak, Adel K ABOU-MRAD, Hosam M
Revisional bariatric surgery (RBS) for insufficient weight loss/weight regain or metabolic relapse is increasing worldwide. There is currently no large multinational, prospective data on 30-day morbidity and mortality of RBS. In this study, we aimed to evaluate the 30-day morbidity and mortality of RBS at participating centres. An international steering group was formed to oversee the study. The steering
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Patient perspectives on personalised medicine for obesity: An IMI2 SOPHIA Study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-06-29 Emma Farrell, Carel W. le Roux, Eva Hollmann, Joseph Nadglowski, Deirdre McGillicuddy
Personalised medicine is seen as an exciting opportunity to improve the health outcomes of people with obesity. As research on phenotyping and personalised treatment for obesity rapidly advances, this study sought to understand patient preferences and perspectives on personalised medicine for obesity. A participatory world café methodology was used to garner the perspectives of people living with obesity
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Approach to duodenal pathology in bariatric surgery: Transit bipartition as an option Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-06-28 Sergi Sanchez-Cordero, Ruth Lopez-Gonzalez, Jordi Pujol-Gebellí, Jordi Castellvi-Valls
Transit bipartition (TB) emerges as a bariatric surgery alternative to Duodenal Switch (DS), emphasizing complete intestinal access and reduced malabsorption. By directly stimulating the distal ileum, TB promotes weight loss while preserving endoscopic duodenal access. This technique enhances anorexigenic hormones, aiding in satiety and weight loss, with lower malnutrition risks than DS. TB shows favorable
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Association between N-terminal pro-brain natriuretic peptide and maximal functional capacity in heart failure with preserved ejection fraction: The modifying role of obesity Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-06-12 Patricia Palau, Gonzalo Núñez, Rafael de la Espriella, Gema Miñana, Eloy Domínguez, Miguel Lorenzo, Laura López, Cristina Flor, Paloma Marín, Antoni Bayés-Genís, Juan Sanchis, Julio Núñez
This study investigates the association between maximal functional capacity (peakVO) and N-terminal pro-brain natriuretic peptide (NT-proBNP) in 133 ambulatory patients with heart failure with preserved ejection fraction (HFpEF), focusing on patients with obesity. Across all participants, NT-proBNP inversely correlated with peakVO. However, this association varied based on obesity status. In patients
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Associations between body mass index, biological age and frailty in the critically ill Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-06-11 Kwok M. Ho
The relationship between body mass index (BMI) and outcomes in the acute care setting is controversial, with evidence suggesting that obesity is either protective - which is also called obesity paradox - or associated with worse outcomes. The purpose of this study was to assess whether BMI was related to frailty and biological age, and whether BMI remained predictive of mortality after adjusting for
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Association between a national behavioral weight management program and real-world weight change Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-06-08 Anna Hung, John A. Pura, Karen M. Stechuchak, Paul A. Dennis, Matthew L. Maciejewski, Valerie A. Smith, Dan V. Blalock, Katherine Hoerster, Susan D. Raffa, Edwin Wong
In a national cohort of Veterans, weight change was compared between participants in a US Department of Veterans Affairs (VA) behavioral weight management program (MOVE!) and matched non-participants, and between high-intensity and low-intensity participants. Retrospective cohort study of Veterans with 1 + MOVE! visits in 2008–2017 were matched to MOVE! non-participants via sequential stratification
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Interleukin-27 is positively correlated with obesity and a decrease in insulin resistance after weight loss Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-05-25 Meiyang Du, Yanju Zhang, Xinying Gao, Xiaolong Xing, Minying Zhang, Mingxin Leng, Xincheng Wang, Shi Zhang, Chunjun Li
Interleukin-27 (IL-27), a potential mediator linking obesity to inflammatory diseases, is considered an important candidate for regulating obesity. The present study evaluated the relationship of IL-27 with obesity and insulin resistance (IR) and further investigated the changes in IL-27 levels after weight loss. The study analyzed 405 participants, of whom 62 with overweight or obesity completed one
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Intrapartum antibiotic use is associated with higher child body mass index (BMI) z-score at 4 years of age Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-05-24 Nicole A. Cho, Gerald F. Giesbrecht, Deborah Dewey, Raylene A. Reimer
Early life antibiotic exposure may increase obesity risk. We investigated if prenatal, intrapartum, or childhood antibiotic use is associated with child BMI score at 4 yrs of age. We included data from the Alberta Pregnancy Outcomes and Nutrition (APrON) study, a prospective cohort study, on maternal and child antibiotic exposure and clinic measures of height and weight at age 4 (n = 408). Prenatal
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Documentation and management of paediatric obesity: Evidence from a paediatric inpatient unit Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-05-17 Hemani Sharma, Anthony Liu, Muhammad Aziz Rahman, Alison Poulton, Habib Bhurawala
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Fat loss and muscle gain: The possible role of cortical glutamate in determining the efficacy of physical exercise Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-05-04 Muhammad Abdullah, Shih-Hsien Lin, Li-Chung Huang, Po See Chen, Huai-Hsuan Tseng, Yen Kuang Yang
Physical exercise is widely acknowledged for its health benefits, but its effectiveness in treating obesity remains contentious due to variability in response. Owing to the roles of glutamate in appetite regulation, food addiction, and impulsivity, this observational cohort-study evaluated medial prefrontal cortex (mPFC) glutamate as a predictor of variability in exercise response, specifically in
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Long-term changes in eating-related problems and quality of life in children with overweight and obesity attending a 10-week lifestyle camp Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-05-04 Dorthe Dalstrup Jakobsen, Kajsa Järvholm, Lea Brader, Jens Meldgaard Bruun
Eating-related problems (e.g., binge eating (BE)) and impaired quality of life (QoL) is more prevalent in children with overweight and obesity. This study aimed to investigate changes in self-reported overeating (OE), BE, and QoL in children with overweight or obesity attending multicomponent 10-week lifestyle camps with a 52-weeks follow-up. Additionally, the study sought to investigate whether self-reported
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Benefits managers’ attitudes toward obesity treatment coverage Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-17 Caroline Ben Nathan, Jennifer Ben Nathan, Yung-Tang Chou, Sukanya M. Joshi, Christine Gallagher, Ariana M. Chao
Despite the existence of effective treatments, obesity continues to present a severe public health crisis. Limited access to treatments works against efforts to reduce obesity prevalence. A major barrier to treatment access is a lack of insurance coverage. This study focused on an important population of stakeholders: benefits managers. The purpose of this study was to explore the relationships between
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Changes in weight status of caregivers of children and adolescents enrolled in a community-based healthy lifestyle programme: Five-year follow-up Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-17 Thomas S. Hadley, Cervantée E.K. Wild, Sarah E. Maessen, Paul L. Hofman, José G.B. Derraik, Yvonne C. Anderson
Whānau Pakari is a family-centred healthy lifestyle programme for children/adolescents with overweight/obesity in New Zealand. This secondary analysis from our randomised trial within the clinical service assessed 5-year BMI changes in accompanying caregivers ( = 23), mostly mothers. Overall, baseline and 5-year caregivers’ BMI were similar (32.50 vs 31.42 kg/m, respectively; = 0.31) but two-thirds
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Effects evaluation of different exercises on subclinical left ventricular dysfunction in obese rats by speckle-tracking echocardiography Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-08 Fengli Tan, Donghui Tang, Pei Su, Tianyi Xu, Yufeng He, Mengyue Wang, Daxin Li, Yangya Feng
To identify subclinical left ventricle dysfunction (LVD) in obese rats by speckle-tracking echocardiography, and to evaluate the effects of 12-week Moderate-Intensity Continuous Training (MICT) or High-Intensity Interval Training (HIIT) on LV geometry, histology and function in obese rats. Eighteen male standard or obese Sprague-Dawley rats were randomly divided into the Control group, the MICT group
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Semaglutide as a potential treatment for obesity in Smith-Kingsmore syndrome (SKS) patients: A mosaic mutation case report Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-06 Jean-baptiste Bonnet, Axelle Trupheme Durieux, Sarah Tournayre, Lucile Marty, Ariane Sultan, Antoine Avignon
We present for the first-time efficacy and tolerability of GLP-1-RA (Semaglutide) in Smith-Kingsmore syndrome (SKS). SKS is a rare genetic disorder characterized by intellectual disability, macrocephaly, seizures and distinctive facial features due to MTOR gene mutation. We present a 22-year-old woman with mosaic SKS and severe obesity (Body Mass Index ≥40 kg/m²), treated with semaglutide. She achieved
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Fat tissue quantity, waist circumference or waist-to-hip ratio in patients with chronic kidney disease: A systematic review and meta-analysis Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-06 Silke Zimmermann, Akash Mathew, Robert Schöppe, Gyulten Mangova, Ronald Biemann, Alexey Surov, Hans-Jonas Meyer, Berend Isermann
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Systolic blood pressure as a critical mediator in the association between adult height and 25-year risk of stroke Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-04 Hsien-Yu Fan, Hsin-Yin Hsu, Hung-Ju Lin, Yun-Yu Chen, Yang-Ching Chen, Ta-Chen Su, Kuo-Liong Chien
Adult height is associated with the risk of stroke. However, the underlying mechanism remains unclear. We explored the mediating role of metabolic factors in the association between adult height and stroke incidence. We used data from 3306 community-dwelling participants with complete information on adult height, metabolic factors, and 25-year cardiovascular outcomes. Participants were classified into
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Associations of gestational weight gain with the long-term postpartum weight gain, body mass index, waist circumference and abdominal obesity: A 27-year prospective cohort study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-04 Abdullah A. Mamun, Emily Oken, Harold D. McIntyre, Jake M. Najman, Gail M. Williams, Alexandra Clavarino, Tolassa W. Ushula
This prospective cohort study aimed to investigate the associations between gestational weight gain (GWG) and long-term postpartum maternal weight gain, body mass index (BMI), waist circumference (WC), and the risk of general and abdominal obesity, beyond motherhood (some 27 y after childbirth). Participants were 1953 women enrolled in the Mater-University of Queensland Study of Pregnancy cohort study
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Differences in healthcare costs over 10 years following discharge from military service by weight trajectory Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-04-01 Edwin S. Wong, Karen M. Stechuchak, Valerie A. Smith, Anna Hung, Paul A. Dennis, Katherine D. Hoerster, Matthew L. Maciejewski
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Renal sinus fat is associated with intrarenal hemodynamic abnormalities independent of visceral fat in patients with chronic kidney disease Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-03-29 Kenji Kaneko, Ryunosuke Mitsuno, Daiki Kojima, Tatsuhiko Azegami, Shotaro Kosugi, Toshifumi Nakamura, Akinori Hashiguchi, Yoshitake Yamada, Masahiro Jinzaki, Shintaro Yamaguchi, Hiroshi Itoh, Jun Yoshino, Kaori Hayashi
Obesity is a risk factor of chronic kidney disease (CKD), contributing to the rising incidence of cardiometabolic diseases. Renal sinus fat (RSF) is an ectopic fat depot located at the renal cavity that could impair renal function and hemodynamic through compression of renal structures. The major purpose of this study was to explore the relationship between RSF accumulation and renal dysfunction in
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Associations of overweight and obesity with the risk of cardiovascular disease according to metabolic risk factors among middle-aged Japanese workers: The Aichi Workers’ cohort study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-03-12 Abubakr Ahmed Abdullah Al-shoaibi, Yuanying Li, Zean Song, Young Jae Hong, Chifa Chiang, Yoshihisa Nakano, Yoshihisa Hirakawa, Masaaki Matsunaga, Atsuhiko Ota, Koji Tamakoshi, Hiroshi Yatsuya
The association between obesity and cardiovascular disease (CVD) remains unclear, particularly for those with established CVD risk factors. We analyzed follow-up data from the Aichi Workers’ Cohort Study. We studied the association between the degree of obesity and risk of CVD and its subtypes specifically among individuals with hypertension, hyper-low-density lipoprotein (LDL)-cholesterolemia, or
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Association with pre-pregnancy BMI on early pregnancy loss in infertility patients in first HRT-FET cycles: A retrospective cohort study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-03-06 Tiantian Cheng, Jingjing Fan, Fang Yuan, Huanhuan Xie, Cuilian Zhang, Qiaohua He
To investigate the association between pre-pregnancy body mass index (BMI) and the early pregnancy loss rate in patients in first hormone replacement therapy-frozen-thawed embryo transfer (HRT-FET) cycles and find the threshold. A retrospective cohort study was conducted using a total of 14030 HRT-FET cycles at the Reproductive Center from January 2017 to December 2021. The association of pre-pregnancy
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Association between weight change, waist circumference change, and the risk of nonalcoholic fatty liver disease in individuals with metabolically healthy overweight or obesity and metabolically unhealthy overweight or obesity Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-03-04 Sailimai Man, Yuhan Deng, Yuan Ma, Xiaochen Yang, Xiaona Wang, Jingzhu Fu, Canqing Yu, Jun Lv, Jing Du, Bo Wang, Liming Li
This study aimed to explore and compare the effect of weight change, and waist circumference (WC) change, on the risk of nonalcoholic fatty liver disease (NAFLD) in individuals with metabolically healthy overweight or obesity (MHOW/O) and metabolically unhealthy overweight or obesity (MUOW/O) in a health check-up cohort in China. 5625 adults with overweight or obesity, and free from NAFLD at baseline
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Postbariatric hypoglycemia, abdominal pain and gastrointestinal symptoms after Roux-en-Y gastric bypass explored by continuous glucose monitoring. Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-23 Kirsti K. Bjerkan, Jorunn Sandvik, Siren Nymo, Gjermund Johnsen, Åsne A. Hyldmo, Bård Eirik Kulseng, Sissel Salater, Kjetil Laurits Høydal, Dag Arne L. Hoff
Abdominal pain and postbariatric hypoglycemia (PBH) are common after bariatric surgery. This study aimed to explore the potential relationship between abdominal pain, gastrointestinal symptoms, and PBH more than a decade after Roux-en-Y gastric bypass (RYGB) and whether continuous glucose monitoring (CGM) with dietary intervention has an educational role in reducing symptoms. At two public hospitals
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Influence of preconception body mass index on perinatal outcomes after metabolic and bariatric surgery Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-23 Diana Rodrigues-Martins, Tiago Esteves, Sara Andrade, Jorge Braga, Inês Nunes, Mariana P. Monteiro
Metabolic and bariatric surgery (MBS) is a very effective weight loss intervention, although does not invariably reverses the obesity status. Our aim was to evaluate whether despite successful weight loss after MBS, persistence of obesity at time of conception still carries additional risks of adverse perinatal pregnancy outcomes. Retrospective study comparing pregnancy outcomes of women previously
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Adipose tissue deposition region affects fall risk in people with obesity: A systematic review and meta-analysis Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-15 Jiyun Ahn, Caroline Simpkins, Feng Yang
This review sought to meta-analyze previous research observing the effects of fat mass distribution on the fall risk among people with obesity. The literature search yielded five qualified studies enrolling 1218 participants (650 with android vs. 568 with gynoid). The outcome variables included the annual fall prevalence (primary outcome) and the center of pressure (COP) movement measurements during
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Duration of therapy of cost-subsidised phentermine and topiramate in patients with obesity: A retrospective medical records audit of an Australian single site Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-15 Jared A. Houssarini, Janet Franklin, Tania Markovic, Samantha L. Hocking
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Trajectories of body mass index before the diagnosis of type 2 diabetes in a cohort of Taiwanese adults Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-08 Tsung Yu, Tzu-Jung Wong, Jen-Wen Chang, Xiang-Qian Lao
Although the prevalence of overweight/obesity is lower in Asian countries, the risk of type 2 diabetes (T2DM) is disproportionally higher. We identified and characterized the trajectory patterns of body mass index (BMI) before the onset of T2DM in a Taiwanese population. Using the Taiwan MJ cohort study, we sampled the health examination data of 22,934 participants, including 7618 cases of T2DM and
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Obesity in patients without diabetes undergoing coronary artery bypass graft surgery: Time to select patients for semaglutide Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-07 Nick S.R. Lan, Umar S. Ali, Robert Larbalestier, Girish Dwivedi, P. Gerry Fegan
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Relationship between metabolically healthy obesity and coronary artery calcification Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-02-06 Yoo-Bin Seo, Sung-Goo Kang, Sang-Wook Song
There is a lack of consensus regarding universally accepted criteria for metabolic health (MH). A simple definition of MH was systematically derived in a recent prospective cohort study. The present cross-sectional study aimed to explore the applicability of these criteria in Korean population, using coronary calcification as an indicator of cardiovascular risk. In total, 1049 healthy participants
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Associations of pancreas fat content and size with markers of iron metabolism Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-26 Wandia Kimita, Loren Skudder-Hill, Xiatiguli Shamaitijiang, Sunitha Priya, Maxim S. Petrov
To comprehensively investigate the associations of pancreas fat content and size with circulating markers of iron metabolism. A total of 116 individuals underwent magnetic resonance imaging and spectroscopy on a 3.0 Tesla scanner, exclusively for the purpose of the COSMOS research programme. Intra-pancreatic fat deposition, total pancreas volume, liver fat content, visceral and subcutaneous fat volumes
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Letter to the Editor: Comment on “Effect of zinc supplementation on blood sugar control in the overweight and obese population: A systematic review and meta-analysis of randomized controlled trials” Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-20 Priscila Berti Zanella
Abstract not available
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Effects of aerobic, resistance, and high-intensity interval training on thermogenic gene expression in white adipose tissue in high fat diet induced obese mice Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-18 Tzu-Jung Chou, Li-Yu Lin, Chia-Wen Lu, Yi-Ju Hsu, Chi-Chang Huang, Kuo-Chin Huang
Global prevalence of obesity has continued to rise and poses public health concerns. Current anti-obesity medications are mainly focused on suppressing appetite. Thermogenic fat cells that increase energy expenditure may be a promising alternative target to combat obesity. Our study aims to investigate the effects of aerobic, resistance, and high-intensity interval training on thermogenic gene expression
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Prevalence and predictors of weight recurrence following bariatric surgery: A longitudinal prospective cohort study from Tehran Obesity Treatment Study (TOTS) Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-16 Minoo Heidari Almasi, Maryam Barzin, Maryam Mahdavi, Alireza Khalaj, Majid Valizadeh, Farhad Hosseinpanah
Considering the lack of a standardized definition for weight recurrence (W), the prevalence and predictors of W remain inconsistent. The prospective study was conducted on 1939 individuals who underwent bariatric surgery;66.8% underwent sleeve gastrectomy (SG), 33.2%, underwent gastric bypass (GB)[of them 87% one-anastomosis gastric bypass (OAGB), and 13% Rue and Y gastric bypass (RYGB)]. Among 1939
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Incidence of type 2 diabetes after gastric by-pass surgery in a Swedish controlled cohort study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-10 Shabbar Jamaly, Christina E. Lundberg, Martin Adiels, Jesper Lagergren, Lena Björck, Annika Rosengren
To assess the long-term risk of developing type 2 diabetes in patients with obesity who have undergone gastric bypass surgery compared to non-operated patients with obesity and the general population. This study included 71,495 patients aged 20–65 years with a principal diagnosis of obesity in the Swedish Patient Register in 2001–2013. Of these, 23,099 had undergone gastric bypass and 32,435 had not
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A multifaceted training tool to reduce weight bias among healthcare students: A randomized controlled trial Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2024-01-05 Shiri Sherf-Dagan, Lani Ofri, Inbar Tayar, Ido Keisar, Assaf Buch, Naama Paska-Davis, Michael Pinus, Riki Tesler, Roni Elran-Barak, Mona Boaz, Gizell Green
Weight bias toward people with obesity (PwO) is common in healthcare settings. Efforts to address weight bias in healthcare settings should begin during university studies. This study aimed to explore the effect of a multifaceted intervention on weight bias among undergraduate healthcare students. An open label randomized controlled trial. The intervention tool consisted of short video lectures on
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What matters for weight loss in behavioral trials in the Latinx community: Learnings from three randomized controlled trials Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-12-09 Patricia Rodriguez Espinosa, Lan Xiao, Jun Ma, Lisa G. Rosas
Background Nearly half of Latinx adults in the US are obese, making effective weight loss interventions crucial to prevent associated chronic conditions. Objective To identify factors associated with increased session attendance and clinically significant weight loss among Latinx adults. Participants Latinx participants from the Vivamos Activos (n = 207), Vida Sana (n = 191), and HOMBRE (n = 424 Latinx
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Cardioprotective effects of calorie restriction against inflammation and apoptosis in ovariectomized obese rats: Role of classical estrogen receptors and SIRT1 Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-12-09 Zahra Hajializadeh, Mohammad Khaksari
Aim Obesity is a metabolic complication linked with bad eating habits and a sedentary lifestyle, and the heart is one of the target organs damaged by it. Estrogen deficiency during menopause worsens the situation. Calorie restriction (CR) can contribute to reducing cardiovascular disease (CVD) in postmenopausal conditions. Thus, the effects of CR on inflammation and apoptosis in ovariectomized rats'
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Validation of the Universal Measure of Bias–Fat (UMB Fat) among Malaysian health practitioners using Rasch analysis Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-12-01 Nor Akma Yunus, Elizabeth Sturgiss, Sze-Ee Soh
Objective This study aimed to evaluate the structural validity of the Universal Measures of Bias – Fat (UMB Fat) among Malaysian healthcare practitioners using Rasch analysis. Methods Data from a cross-sectional survey of 268 public and private doctors and allied health practitioners in Peninsular Malaysia were used for this analysis. Using Rasch analysis, overall model fit and item fit of the summary
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Strengths and weaknesses of telemedicine: Survey analysis in a single center bariatric surgery program Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-28 Carolina Baz, Francisco Schlottmann, Amber Pirzada, Mario A. Masrur
Background Despite Telemedicine being considered by most patients as the preferred follow-up method, bariatric surgery programs that include virtual consults still exhibit high attrition rates. This study analyzed the strengths and weaknesses of telemedicine in a single-center bariatric surgery program. Methods We developed a 5-minute, 10-question online survey via Qualtrics and examined the results
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Nonhepatic hyperammonemic encephalopathy following bariatric surgery: A systematic review Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-25 Nasser Sakran, Chetan Parmar, Sjaak Pouwels
Background Nonhepatic Hyperammonemic encephalopathy (NHAE) following Bariatric Surgery (BS), mainly Roux-en-Y Gastric Bypass (RYGB) and Biliopancreatic Diversion (BPD) is a potentially devastating condition if not diagnosed and managed promptly. Methods A literature review was performed using PRISMA guidelines. Eighteen studies and 3 conference abstracts with a total of 33 patients were included in
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Factors contributing to whether or not people with obesity undergo bariatric surgery Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-24 Chi-Whan Choi, Daniel Cunha, Christine Helfrich, Simone V. Gill
Background Bariatric surgery has been suggested as a safe and effective way to treat obesity by facilitating weight loss, but factors that predict the likelihood of bariatric surgery are unknown. The objective of this study was to describe factors associated with individuals with obesity that influence their decision to undergo bariatric surgery. Subjects and methods The study design was a cross-sectional
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Neck Circumference and Cardio-metabolic Variable in General Population Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-07 Kyu Rae Lee, In Cheol Hwang, Kyoung Kon Kim
Abstract not available
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Exploring the Relationship Between Obesity and Breast Cancer Treatment Outcomes Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-07 Chih-Yu Hsu, Hsiang-Sheng Wang, Tse-Ching Chen, Hai-Hua Chuang
Abstract not available
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Exploring the Potential of Thai Herbal Medicines for Obesity Therapy by Modulating Intestinal-Fat Cell Interaction: In Vitro Model Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-07 Chartchai Chaichana, Piyavee Kongsungnoen, Pakwuan Wongshaya, Thaniya Suwanmalai, Pornpoj Pramyothin
Abstract not available
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The Long-term Effects of Intentional Weight Loss on Obesity-related Morbidity and Mortality in East and South Asian Populations: A Systematic Review Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-07 Thomas Lew, Annabel Barrett, Josefine Redig, Naveen Kayam
Abstract not available
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Impact of Metabolic-Bariatric Surgery on Weight Loss Outcomes in an Asian Cohort: A 10-year Follow-up Study Obes. Res. Clin. Pract. (IF 2.5) Pub Date : 2023-11-07 Yong Qin Lee, Wei Lum Gwyneth Syn, Fan Shuen Tseng, Phong Ching Lee, Sarah Ying Tse Tan, Hong Chang Tan, Tse Lin Emily Ho, Jean-Paul Kovalik, Tian Hui Jeremy Tan, Weng Hoong Chan, Kim Hock Alvin Eng, Chin Hong Lim, Kee Wee Eugene Lim, Jian Ying Tiffany Lye, Zhen Jin Lee, XiangYing Angelina Foo, Yoke Ling Chan, Giat Yeng Khee, Paik Shia Lim, Kai Ling Jasmine Chua
Abstract not available