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‘Effects of dehydration on central blood pressure in young healthy adults’ Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-09-13 Madeleine L. Giddings, Jacob P. Auringer, Nathan F. Meier, Elizabeth C. Lefferts, Chong Wang, Lindsay Kane‐Barnese
PurposeBrachial blood pressure (BP) is the current gold standard for BP assessment; however, measures of pulse wave velocity (PWV) and central blood pressure (CBP) may contribute uniquely to assessment of cardiovascular health status. As of yet, standards for assessment of CBP and PWV have not addressed the impact of hydration status on proper measurement. To understand the impact of hydration, PWV
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The concurrent validity of a portable ultrasound probe for muscle thickness measurements Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-09-06 Kai A. Homer, Matt R. Cross, Ivan Jukic
Ultrasound imaging is extensively used by both practitioners and researchers in assessing muscle thickness (MT); however, its use in the field is constrained by the transportability of stationary devices. New portable ultrasound probes pose as a cost‐effective and transportable alternative for field‐based assessments. This study evaluated the concurrent validity of a portable probe (Lumify) against
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Tortuosity of the left anterior descending artery is associated with hypertension and is not independently related to physical performance: A cardiac computed tomography study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-08-30 Alaa Sharfo, Malthe Faurschou Wandall‐Holm, Jesper James Linde, Ida Hæsum, Graversen Peter Laursen, Klaus Fuglsang Kofoed, Jens Dahlgaard Hove
BackgroundCoronary tortuosity (CorT) is frequently observed in invasive angiography, though its aetiology and clinical significance remain ambiguous. Prior research has indicated possible links between CorT and factors such as hypertension, age, and calcium scores in the left anterior descending (LAD) artery. The aim of this study was to examine and optimize the usage of coronary computed tomography
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Short‐ and long‐term prognostic performance of exercise ECG and myocardial perfusion SPECT Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-08-18 M. Kraen, S. Akil, B. Hedén, B. Kjellström, J. Berg, E. Ostenfeld, H. Arheden, M. Carlsson, H. Engblom
BackgroundMyocardial perfusion SPECT (MPS) and exercise electrocardiography (Ex‐ECG) results are of prognostic importance for short‐term follow up duration. However, the value of MPS or Ex‐ECG findings for long‐term risk assessment is less evident as underlying risk factors for ischemic heart disease (IHD) gain in importance.ObjectivesTo assess the short‐ and long‐term prognostic value of MPS and Ex‐ECG
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Impact of moderate‐intensity aerobic exercise in combined hypoxic and hot conditions on endothelial function Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-06-23 Takuma Morishima, Keiichi Yamaguchi, Kazushige Goto
There is no study that has investigated the impact of exercise in a combined hypoxic and hot environment on endothelial function. Therefore, we tested whether aerobic exercise in a combined hypoxic and hot conditions induces further enhancement of endothelial function. Twelve healthy males cycled at a constant workload (50% of their maximal oxygen uptake under normoxic/thermoneutral conditions) for
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Relation of changes in peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) during bronchoconstriction Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-06-23 Leon L. Csonka, Antti Tikkakoski, Liisa Vuotari, Jussi Karjalainen, Lauri Lehtimäki
Diagnosis of asthma can be confirmed based on variability in peak expiratory flow (PEF) or changes in forced expiratory volume in 1 s (FEV1) measured with spirometry. Our aim was to use methacholine challenge as a model of induced airway obstruction to assess how well relative changes in PEF reflect airway obstruction in comparison to relative changes in FEV1. We retrospectively studied 878 patients
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Cutting corners in muscle measurements with ISarcoPRM! Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-06-16 Ahmad J Abdulsalam
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Effects of combined training on nonshivering thermogenic activity of muscles in individuals with overweight and type 2 diabetes. Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-06-16 Enrico Antonio Rautenberg Finardi,Ivan Luiz Padilha Bonfante,Milena Monfort-Pires,Renata Garbellini Duft,Keryma Chaves da Silva Mateus,Sergio Querino Brunetto,Mara Patricia T Chacon-Mikahil,Celso Darío Ramos,Licio Augusto Velloso,Cláudia R Cavaglieri
BACKGROUND Increased thermogenic activity has shown to be a promising target for treating and preventing obesity and type 2 diabetes (T2DM). Little is known about the muscular influence on nonshivering thermogenesis (NST), and it remains unclear whether physical training and potential metabolic improvements could be associated with changes in this type of thermogenic activity. OBJECTIVE The present
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The patterns in urine excretion and transvascular fluid exchange in human subjects during intravenous fluid infusion: A quantitative analysis Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-05-16 FitzRoy E. Curry, C. Charles Michel
IntroductionInvestigations of responses of animals and humans to changes of plasma volume are usually reported as average responses of groups of individuals. This ignores considerable quantitative variation between individuals. We examined the hypothesis that individual responses follow a common temporal pattern with variations reflecting different parameters describing that pattern.MethodsWe illustrate
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Normal baseline cardiac autonomic function and increased pupillary parasympathetic tone in patients with vasovagal syncope Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-28 Udi Nussinovitch, Sapir Barak‐Lanciano, Itay Shavit, Ishay Avivi, Ella Haber‐Kaptsenel, Hagar Palacci, Chen Chaiat, Ronen Rubinshtein
It is controversial whether people with vasovagal syncope (VVS) have abnormal autonomic responses at baseline and whether specific diagnostic manoeuvres have a diagnostic value. We investigated whether the pupillary light reflex and cardiac autonomic tests can be used to identify autonomic dysfunction in volunteers with a medical history of VVS. The study groups included 128 healthy volunteers, of
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Reproducibility and sex differences in muscle oxygenation during brachial artery occlusion in healthy participants Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-26 Tommi Jeskanen, Venla Ylinen, Rasmus I. P. Valtonen, Mikko P. Tulppo
SignificanceNear‐infrared spectroscopy (NIRS) measurement is a widely used technique to measure muscle oxygenation. A knowledge of the reproducibility of NIRS measurements is essential for the correct interpretation of data.AimOur aim was to test the reproducibility and sex differences of NIRS measurements during brachial artery occlusion in healthy participants.ApproachAn NIRS device was used to measure
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Peripheral quantitative computed tomography is a valid imaging technique for tracking changes in skeletal muscle cross‐sectional area Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-26 Bradley A. Ruple, Christopher G. Vann, Casey L. Sexton, Shelby C. Osburn, Morgan A. Smith, Joshua S. Godwin, Petey W. Mumford, Matt S. Stock, Michael D. Roberts, Kaelin C. Young
Peripheral quantitative computed tomography (pQCT) has recently expanded to quantifying skeletal muscle, however its validity to determine muscle cross‐sectional area (mCSA) compared to magnetic resonance imaging (MRI) is unknown. Eleven male participants (age: 22 ± 3 y) underwent pQCT and MRI dual‐leg mid‐thigh imaging before (PRE) and after (POST) 6 weeks of resistance training for quantification
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Association of postsystolic shortening on stress echocardiography and significant coronary artery stenosis: A single‐centre retrospective cohort study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-25 Joel Toftgård, Henrik Hedskog, Lars Rune, Jan Svedenhag, Gabriel Riva
BackgroundPostsystolic shortening (PSS) is one of the proposed quantitative measures to predict myocardial ischaemia in the stress echocardiographic (SE) evaluation. It is previously known that hypo‐/akinesia (HA) correlates well with coronary stenosis. However, some patients undergoing SE only present with PSS, and their risk of significant coronary stenosis is less clear. This study aimed to evaluate
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Skeletal muscle architecture and aging: A comparison of ultrasound techniques and an assessment of intrarater reliability Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-15 Andrew C. D'Lugos, Nathan J. Skotak, Jacquelyn J. Faris, Nicholas T. Thomas, Corey E. Mazo, Jonathan J. Dickinson, Jessy G. Moore, Theresa M. Jorgensen, Jared M. Dickinson
ObjectiveTo assess intrarater reliability of ultrasound‐determined measurements of skeletal muscle characteristics across different measurement outcomes, imaging techniques, and age groups.Methods2D ultrasound images (B‐mode) of the quadriceps were obtained from young (26 ± 4 year, n = 8 M, 8 F) and older (70 ± 7 year, n = 7 M, 5 F) adults on two occasions, separated by 6 ± 3 days. With participants
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Point‐of‐care β‐hydroxybutyrate measurement predicts adequate glucose metabolism suppression in cardiac FDG‐PET/CT Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-08 Suvi Hartikainen, Tuomo Tompuri, Tiina Laitinen, Tomi Laitinen
AimsThe aims of our study were to evaluate whether point‐of‐care β‐hydroxybutyrate (BHB) measurement can be used to identify patients with adequate cardiac glucose metabolism suppression for cardiac [18F]‐fluoro‐2‐deoxy‐ d‐glucose‐positron emission tomography with computerized tomography (FDG‐PET/CT) and to develop a pretest probability calculator of myocardial suppression using other metabolic factors
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Pulmonary volumes and signs of chronic airflow limitation in quantitative computed tomography Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-05 Emelie Bäcklin, Adrian Gonon, Magnus Sköld, Örjan Smedby, Eva Breznik, Birgitta Janerot‐Sjoberg
BackgroundComputed tomography (CT) offers pulmonary volumetric quantification but is not commonly used in healthy individuals due to radiation concerns. Chronic airflow limitation (CAL) is one of the diagnostic criteria for chronic obstructive pulmonary disease (COPD), where early diagnosis is important. Our aim was to present reference values for chest CT volumetric and radiodensity measurements and
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Improving sensitivity through data augmentation with synthetic lymph node metastases for AI‐based analysis of PSMA PET‐CT images Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-04-02 Elin Trägårdh, Johannes Ulén, Olof Enqvist, Lars Edenbrandt, Måns Larsson
BackgroundWe developed a fully automated artificial intelligence (AI)AI‐based‐based method for detecting suspected lymph node metastases in prostate‐specific membrane antigen (PSMA)(PSMA) positron emission tomography‐computed tomography (PET‐CT)(PET‐CT) images of prostate cancer patients by using data augmentation that adds synthetic lymph node metastases to the images to expand the training set.MethodsSynthetic
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Respiratory muscles's thermographic analysis in asthmatic youth with and without bronchospasm induced by eucapnic voluntary hyperpnea Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-03-28 Camila M. de A. Santos, Polyanna G. C. Quirino, José Â. Rizzo, Décio Medeiros, José J. de A. Ferreira, Manoel da C. Costa, Nádia Gaua, Bayne Freya, Marcelle de O. Martins, Marco A. C. V. Junior
ObjectiveTo compare the thermographic pattern of regions of interest (ROI) of respiratory muscles in young asthmatics with and without bronchospasm induced by eucapnic voluntary hyperpnea (EVH).Materials and MethodsCross‐sectional study carried out with 55 young (55% male and 45% females) aged 12.5 ± 3.3 years, divided in nine nonasthmatics, 22 asthmatics without exercise‐induced bronchospasm compatible
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Acute cardiac autonomic and hemodynamic responses to resistive breathing: Effect of loading type and intensity Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-03-18 Karan Pongpanit, Manta Korakot, Peerakan Nitilap, Nopparat Puplab, Noppawan Charususin, Kornanong Yuenyongchaiwat
ObjectivesThis study aimed to assess the acute impact of distinct loading breathing types and intensities on cardiac autonomic function and hemodynamic responses in healthy young adults.MethodsA randomized, crossover trial involved 28 participants who underwent inspiratory resistive breathing, expiratory resistive breathing (ERB) and combined resistive breathing, each at 30% and 60% of maximal respiratory
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Intersession reliability of lower limb muscle strength assessments in adults with obesity eligible for bariatric surgery Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-03-11 Søren Gam, Anders K. Petz, Lukas R. Bjerre, Jeppe Bøgild, Anders B. Nielsen, Rikke N. Sørensen, Mikkel I. Kolind, Bibi Gram, Stinus Hansen, Per Aagaard
BackgroundThe aim of this study was to examine the test−retest reliability in lower limb muscle strength and rate of torque development (RTD) using isokinetic dynamometry in adults with obesity, with a body mass index (BMI) ≥ 35 kg/m2.MethodThirty‐two adults with a BMI of 43.8 ± 6.6 kg/m2 eligible for bariatric surgery were enroled in the study. Isokinetic and isometric knee extensor (KE) and flexor
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Skeletal muscle estimation: A review of techniques and their applications Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-03-01 Christian Rodriguez, Jacob D. Mota, Ty B. Palmer, Steven B. Heymsfield, Grant M. Tinsley
Quantifying skeletal muscle size is necessary to identify those at risk for conditions that increase frailty, morbidity, and mortality, as well as decrease quality of life. Although muscle strength, muscle quality, and physical performance have been suggested as important assessments in the screening, prevention, and management of sarcopenic and cachexic individuals, skeletal muscle size is still a
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Rebooting nuclear medicine specialist education under the COVID‐19 pandemic: From plenary lectures to active e‐learning Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-02-28 Andreas Tulipan, Ankush Gulati, Torjan Haslerud, Robert Gray, Martin Biermann
Despite major reforms of specialist training in the Nordic countries towards concrete learning outcomes and promoting active learning, most specialist courses continue to be based on lectures. We redesigned our mandatory 5‐day course in clinical nuclear medicine (NM) that was last held in 2016 towards active learning. Thirty 1‐h lectures were replaced with 10 thematic blocks of 3 h each. Each block
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Lower limb blood flow occlusion increases systemic pressor response without increasing brachial arterial blood flow redistribution in women Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-02-25 Abby R. Fleming, Hayley V. MacDonald, Samuel L. Buckner, Lee J. Winchester
This study was conducted to investigate the systemic hemodynamic and vascular changes in women during and after two commonly used clinical blood flow restriction (BFR) pressures at rest. There are minimal data regarding the independent effects of BFR on hemodynamic and systemic vascular changes due to pressor response, particularly among women. Therefore, this study investigated BFR‐induced alterations
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Quantitative computed tomography angiography evaluation of the coronary fractional flow reserve in patients with left anterior descending artery myocardial bridging Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-02-14 Dan Zhang, Xin Tian, Meng-Ya Li, Wen-Song Zheng, Yang Yu, Hao-Wen Zhang, Tong Pan, Bu-Lang Gao, Cai-Ying Li
To quantitatively investigate the effect of myocardial bridge (MB) in the left anterior descending artery (LAD) on the fractional flow reserve (FFR).
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Resting strain analysis to identify myocardial ischemia in patients with advanced chronic kidney disease Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2024-02-05 Dimitrios Tsartsalis, Yannis Dimitroglou, Argyro Kalompatsou, Markos Koukos, Dimitrios Patsourakos, Elias Tolis, Spiros Tzoras, Dimitrios Petras, Costas Tsioufis, Constantina Aggeli
Chronic kidney disease (CKD) is associated with higher incidence of cardiovascular death. Screening for coronary artery disease in asymptomatic or mildly symptomatic patients is challenging.
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Is musculoskeletal pain associated with increased muscle stiffness? Evidence map and critical appraisal of muscle measurements using shear wave elastography Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-12-28 Andreas Haueise, Guillaume Le Sant, Angelika Eisele-Metzger, Angela V. Dieterich
Approximately 21% of the world's population suffers from musculoskeletal conditions, often associated with sensations of stiff muscles. Targeted therapy requires knowing whether typically involved muscles are objectively stiffer compared to asymptomatic individuals. Muscle stiffness is quantified using ultrasound shear wave elastography (SWE). Publications on SWE-based comparisons of muscle stiffness
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Impact of a cuff-based device calibration method on the agreement between invasive and noninvasive aortic and brachial pressure Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-28 Daniel Bia, Federico Salazar, Luis Cinca, Marcos Gutierrez, Álvaro Facta, Alejandro Diaz, Yanina Zócalo
Brachial cuff-based methods are increasingly used to estimate aortic systolic blood pressure (aoSBP). However, there are several unresolved issues.
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Metabolic tumour volume in Hodgkin lymphoma—A comparison between manual and AI-based analysis Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-27 May Sadik, Sally F. Barrington, Elin Trägårdh, Babak Saboury, Anne L. Nielsen, Annika L. Jakobsen, Jose L. L. Gongora, Jesus L. Urdaneta, Rajender Kumar, Lars Edenbrandt
To compare total metabolic tumour volume (tMTV), calculated using two artificial intelligence (AI)-based tools, with manual segmentation by specialists as the reference.
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Right ventricular function in severe aortic stenosis assessed by echocardiography and MRI Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-20 Erica Holmberg, Éva Tamás, Eva Nylander, Jan Engvall, Hans Granfeldt
The prevalence of aortic valve stenosis (AS) is increasing due to an ageing population. Despite that right ventricular function has prognostic value for postoperative outcome, the right ventricle (RV) is not extensively studied and often not routinely assessed in AS. Our aim was to explore the relation between severe AS and RV function in a surgical aortic valve replacement (SAVR) cohort, comparing
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The effect of lower limb strengthening exercise on orthostatic blood pressure and the skeletal muscle pump in older people with orthostatic hypotension Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-17 James Frith, Lisa Robinson, Jake Ryan Gibbon, John Allen
Activation of muscles during standing is recommended to activate the skeletal muscle pump, increasing venous return and increasing blood pressure (BP) in people with orthostatic hypotension (OH).
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A case of hemichorea associated with nonketotic hyperglycaemia: A new magnetic resonance spectroscopy (MRS) finding and possible future implications Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-14 Assunta Trinchillo, Flavio Barchetti, Gabriella De Joanna, Marcello Esposito, Giovanni Piccirillo, Stefania Miniello
Diabetic Striatopathy (DS) is a rare complication of a poor-controlled Diabetes Mellitus consisting of sudden onset of movement disorders. To date, there is still poor knowledge about the pathogenesis.
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Relation of changes in PEF and FEV1 in exercise challenge in children Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-11-07 Leon Csonka, Antti Tikkakoski, Anna P. Tikkakoski, Jussi Karjalainen, Lauri Lehtimäki
Decrease in forced expiratory volume in one second (FEV1) of 10% or 15% in exercise challenge test is considered diagnostic for asthma, but a decrease of 15% in peak expiratory flow (PEF) is recommended as an alternative. Our aim was to assess the accuracy of different PEF cut-off points in comparison to FEV1.
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Enhanced interleukin-6 in human adipose tissue vein after sprint exercise: Results from a pilot study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-29 Mona Esbjörnsson, Barbara Norman, Moa Persson, Amarjit Saini, Jens Bülow, Eva Jansson
Low-volume sprint exercise is likely to reduce body fat. Interleukin (IL-6) may mediate this by increasing adipose tissue (AT) lipolysis. Therefore, the exchange of AT IL-6 and glycerol, a marker of lipolysis, was examined in 10 healthy subjects performing three 30-s all-out sprints.
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Influence of different time framings, reconstruction algorithms and post-processing methods on the quantification of myocardial blood flow from 13N-NH3 PET images Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-26 Shahnaz Akil, Anna E. Székely, Fredrik Hedeer, Berit Olsson, Henrik Engblom, Cecilia Hindorf
The aim was to investigate to what extent the quantification of myocardial blood flow (MBF) from dynamic 13N-NH3 positron emission tomography (PET) images is affected by time frame schemes, time-of-flight (ToF), reconstruction algorithms, blood pool volume of interest (VOI) locations and compartment models in patients with suspected chronic coronary syndrome.
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Impact of regular cold exposure on electrical skin resistance in patients with joint degenerative diseases Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-20 Marcin Machnia, Wafa Douzi, Hela Jdidi, Elzbieta Miller, Benoit Dugué
Common features in chronic inflammatory disease patients (CIDP) are inflammation, mental stress (MS), and autonomic nervous system imbalance. Whole-body cryotherapy (WBC) exposure and regular physical exercise are known to regulate these features. In this study, we assessed the impact of regular physical exercise and the use of WBC exposure in CIDP on the level of electrical skin resistance (SR) to
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Tilt table testing, methodology and practical insights for the clinic Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-15 Steven van Zanten, Richard Sutton, Viktor Hamrefors, Artur Fedorowski, Frederik J. de Lange
Tilt table testing (TTT) has been used for decades to study short-term blood pressure (BP) and heart rate regulation during orthostatic challenges. TTT provokes vasovagal reflex in many syncope patients as a background of widespread use. Despite the availability of evidence-based practice syncope guidelines, proper application and interpretation of TTT in the day-to-day care of syncope patients remain
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Agreement between self-reported and objectively assessed physical activity among out-of-hospital cardiac arrest survivors Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-13 Katarina Heimburg, Gisela Lilja, Erik Blennow Nordström, Hans Friberg, Lisa Gregersen Oestergaard, Anders M. Grejs, Thomas R. Keeble, Marco Mion, Niklas Nielsen, Christian Rylander, Magnus Segerström, Ida Katrine Thomsen, Susann Ullén, Johan Undén, Matthew P. Wise, Tobias Cronberg, Åsa B. Tornberg
Low level of physical activity is a risk factor for new cardiac events in out-of-hospital cardiac arrest (OHCA) survivors. Physical activity can be assessed by self-reporting or objectively by accelerometery.
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Switch to gliflozins and biventricular function improvement in patients with chronic heart failure and diabetes mellitus Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-05 Michele Correale, Pietro Mazzeo, Martino Fortunato, Matteo Paradiso, Andrea Furore, Angela I. Fanizzi, Lucia Tricarico, Giuseppe Pastore, Simona Alfieri, Natale D. Brunetti, Olga Lamacchia
SGLT2 inhibitors have been shown to reduce hospitalisation in patients with chronic heart failure (CHF). The cardioprotective mechanisms of gliflozins however have not been fully elucidated. The aim of this study was therefore to evaluate the effect of SGLT2 inhibitors on right and left ventricular function in patients with diabetes and HF.
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Age-related changes in muscle thickness, echo intensity and shear modulus of the iliocapsularis Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-10-03 Haruka Sakata, Hiroshige Tateuchi, Masahide Yagi, Kotono Kobayashi, Noriaki Ichihashi
This study aimed to clarify age-related changes in the iliocapsularis (IC) using indicators of quantity, quality, and mechanical properties. We also compared the age-related changes in the IC and other hip muscles.
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Influence of physical post-exercise recovery techniques on vagally-mediated heart rate variability: A systematic review and meta-analysis Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-09-27 Sylvain Laborde, Jannik Wanders, Emma Mosley, Florian Javelle
In sports, physical recovery following exercise-induced fatigue is mediated via the reactivation of the parasympathetic nervous system (PNS). A noninvasive way to quantify the reactivation of the PNS is to assess vagally-mediated heart rate variability (vmHRV), which can then be used as an index of physical recovery. This systematic review and meta-analysis investigated the effects of physical recovery
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Effects of low workload respiratory training with steam inhalation on lung function in stable asthma: A controlled clinical study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-09-25 Ilpo Kuronen, Jukka Heinijoki, Anssi Sovijärvi
To investigate effects of low workload respiratory muscle training (RMT) on respiratory muscle power and lung function in asthmatics, we recruited asthmatic persons who performed a 4-week training programme. The training included 20 daily ex- and inhalations with counter pressure 30% from the individual maximal expiratory pressure (MEP). Lung function was measured before and after the training programme
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Quantitative myocardial perfusion should be interpreted in the light of sex and comorbidities in patients with suspected chronic coronary syndrome: A cardiac positron emission tomography study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-08-29 Anna Székely, Katarina Steding-Ehrenborg, Daniel Ryd, Fredrik Hedeer, Kristian Valind, Shahnaz Akil, Cecilia Hindorf, Erik Hedström, David Erlinge, Håkan Arheden, Henrik Engblom
Diagnosis and treatment of patients with suspected chronic coronary syndrome (CCS) currently relies on the degree of coronary artery stenosis and its significance for myocardial perfusion. However, myocardial perfusion can be affected by factors other than coronary stenosis. The aim of this study was to investigate to what extent sex, age, diabetes, hypertension and smoking affect quantitative myocardial
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First clinical experience of a ring-configured cadmium zinc telluride camera: A comparative study versus conventional gamma camera systems Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-08-17 Irma Cerić Andelius, David Minarik, Eva Persson, Henrik Mosén, Kristian Valind, Elin Trägårdh, Jenny Oddstig
A novel semiconductor cadmium zinc telluride (CZT) gamma camera system using a block sequential regularized expectation maximization (BSREM) reconstruction algorithm is now clinically available. Here we investigate how a multi-purpose ring-configurated CZT system can be safely applied in clinics and describe the initial optimization process.
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Effect of blood flow restriction with low-load exercise on muscle damage in healthy adults: A systematic review of randomized controlled trials Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-08-14 Jinchao Yang, Fenghao Ma, Qian Wang, Yuanfen Cui, Jun Zheng
Blood flow restriction (BFR) is a relatively new rehabilitative technique and low-load exercise combined with BFR (LL-BFR) can increase muscle strength and muscle mass. However, it is currently unknown whether LL-BFR causes muscle damage. Therefore, the aim of this study is to investigate the effects of LL-BFR on muscle damage and provide recommendations for sports training and physical exercise.
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A retrospective head-to-head comparison of the Lugano classification and PERCIST for FDG-PET/CT response assessment in diffuse large B-cell lymphoma Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-27 Nicklas B. Nielsen, Oke Gerke, Anne L. Nielsen, Karen Juul-Jensen, Thomas S. Larsen, Michael B. Møller, Malene G. Hildebrandt
Diffuse large B-cell lymphoma (DLBCL) is the most common form of lymphoma. European guidelines recommend FDG-PET/CT for staging and end of treatment (EOT) response assessment, mid-treatment response assessment is optional. We compared the Lugano classification and PET Response Criteria In Solid Tumours (PERCIST) for FDG-PET/CT response assessment in DLBCL head-to-head.
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Heart rate stability in a clinical setting and after a short exercise in healthy male volunteers Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-17 Fleur W. H. Wildenbeest, Gert-Jan Hassing, Michiel J. B. Kemme, Matthijs Moerland, Pim Gal
Limited data exist on heart rate stabilization in the domiciled nature of phase I clinical studies, particularly when frequent measurements of QT intervals are involved. The present analysis aimed to evaluate heart rate stability in the domiciled nature of, and stabilization after a short exercise.
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Association between abdominal muscle stiffness, diaphragm thickness and peak expiratory flow in younger versus older adults Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-16 Youngeun Lim, Yerim Do, Haneul Lee
The present study aimed to evaluate forced expiration based on transverse abdominis (TrA) stiffness by identifying the relationship between TrA stiffness and peak expiratory flow (PEF) in both younger and older adults. We also assessed the relationship between diaphragm thickness and PEF. A total of 31 younger (21.24 ± 2.73 years) and 34 older (71.35 ± 5.26 years) adults were included in the present
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Young type 1 diabetes subjects sway more than healthy persons when somatosensory system is challenged in static standing postural stability tests Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-16 Kim J. Lesch, Vesa V. Hyrylä, Timo Eronen, Saana Kupari, Lauri Stenroth, Mika Venojärvi, Mika P. Tarvainen, Heikki O. Tikkanen
In type 1 diabetes, it is important to prevent diabetes-related complications and postural instability may be one clinically observable manifestation early on. This study was set to investigate differences between type 1 diabetics and healthy controls in variables of instrumented posturography assessment to inform about the potential of the assessment in early detection of diabetes-related complications
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Cardiac morbidity and the cause of death in elderly patients with prostate cancer and incidental cardiac uptake on bone scintigraphy Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-08 Eero Juntunen, Olli Suomalainen, Sorjo Mätzke, Tiina Heliö, Antti Loimaala, Valtteri Uusitalo
Cardiac transthyretin amyloidosis (ATTR) is a possible incidental finding on bone scintigraphy imaged due to prostate cancer. We investigated its significance in 1426 elderly prostate cancer patients (>70 years) who underwent bone scintigraphy in three nuclear medicine departments in Finland. Patients with Perugini grade two or three uptakes were considered positive for cardiac uptake. Heart failure
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Lobar quantification of pulmonary perfusion prior to minimally invasive lung reduction improves prediction of postprocedure outcomes: A pilot study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-08 Kritika Subramanian, Brett Muench, Eugene Shostak, Amanda Coffey, Lady Sawoszczyk, Fei Gao, Adam Leep, Ramya Rajaram, John Hornung, Elisabeth O'Dwyer
Endobronchial valve placement is a minimally invasive option for treatment of patients with severe emphysema, by reducing lung volumes in lobes with both poor ventilation and perfusion; ventilation is determined by emphysematous scores and perfusion by quantitative lung perfusion imaging. CT-based fissure identifying artificial intelligence algorithms have recently demonstrated enhanced quantification
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Erratum Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-03
In Valind et al. (2023), estimated glomerular filtration rate (eGFR) values using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation were incorrectly calculated. As a result of this, the regression equations presented in Equations 1, 3, 5 and 7 were incorrect. In consequence, the resulting R2 values presented in Table 2 and graphical representations in Figure 2 and Figure 3 were
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Regional motion of the AV-plane is related to the cardiac anatomy and deformation of the AV-plane. Data from the HUNT study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-07-03 Asbjørn Støylen, Harald E. Mølmen, Håvard Dalen
The study examines global and regional systolic shortening of the left (LV) and right ventricle (RV) in 1266 individuals without evidence of heart disease in the third wave of the HUNT study. Regional mitral annular systolic displacement (mitral annular plane systolic excursion [MAPSE]) was 1.5 cm in the septum and anterior walls, 1.6 cm in the lateral wall and 1.7 cm in the inferior wall, global mean
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Effect of cryothermic and radiofrequency Cox-Maze IV ablation on atrial size and function assessed by 2D and 3D echocardiography, a randomized trial. To freeze or to burn Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-19 Gabriella Boano, Farkas Vánky, Meriam Åström Aneq
Atrial linear scars in Cox-Maze IV procedures are achieved using Cryothermy (Cryo) or radiofrequency (RF) techniques. The subsequent postoperative left atrial (LA) reverse remodelling is unclear. We used 2- and 3-dimensional echocardiography (2-3DE) to compare the impact of Cryo and RF procedures on LA size and function 1 year after Cox-maze IV ablation concomitant with Mitral valve (MV) surgery.
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Cerebrovascular and cardiovascular responses to the Valsalva manoeuvre during hyperthermia Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-18 Blake G. Perry, Stephanie Korad, Toby Mündel
During hyperthermia, the perturbations in mean arterial blood pressure (MAP) produced by the Valsalva manoeuvre (VM) are more severe. However, whether these more severe VM-induced changes in MAP are translated to the cerebral circulation during hyperthermia is unclear.
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Cardiorespiratory fitness components in relation to clinical characteristics, disease state and medication intake: A patient registry study Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-14 Nicholas Cauwenberghs, Josephine Sente, František Sabovčik, Evangelos Ntalianis, Kristofer Hedman, Jomme Claes, Kaatje Goetschalckx, Véronique Cornelissen, Tatiana Kuznetsova
Interpretation of cardiopulmonary exercise testing (CPET) results requires thorough understanding of test confounders such as anthropometrics, comorbidities and medication. Here, we comprehensively assessed the clinical determinants of cardiorespiratory fitness and its components in a heterogeneous patient sample.
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Four- to seven-year follow-up of pharmacological postconditioning with mangafodipir as an adjunct to primary PCI in ST-segment elevation myocardial infarction Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-10 Walid El-Saadi, Jan Engvall, Jan-Erik Karlsson, Eva Maret
Adverse left ventricular remodelling (AR) develops over time in approximately 30% of patients with a history of coronary artery disease. AR manifests as a structural change in the left ventricle (LV) in terms of increased volumes and reduced left ventricular ejection fraction (LVEF). Manganese dipyridoxyl diphosphate (mangafodipir) has demonstrated interesting cardioprotective features in acute myocardial
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Heart rate variability and haemodynamic function in individuals with hypertrophic cardiomyopathy Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-09 Alaa I. Alyahya, Sarah J. Charman, Nduka C. Okwose, Amy S. Fuller, Christopher Eggett, Peter Luke, Kristian Bailey, Guy A. MacGowan, Djordje G. Jakovljevic
Heart rate variability (HRV) is a measure of cardiac autonomic function. This study: (1) evaluated the differences in HRV and haemodynamic function between individuals with hypertrophic cardiomyopathy (HCM) and healthy controls, and (2) determined the relationship between HRV and haemodynamic variables in individuals with HCM.
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End-tidal oxygen partial pressure is a strong prognostic predictive factor in patients with cardiac disease Clin. Physiol. Funct. Imaging (IF 1.3) Pub Date : 2023-06-09 Asami Ogura, Kazuhiro P. Izawa, Hideto Tawa, Masaaki Wada, Masashi Kanai, Ikko Kubo, Ayano Makihara, Ryohei Yoshikawa, Yuichi Matsuda
Cardiopulmonary exercise testing (CPET) variables represent central and peripheral factors and combined factors in the pathology of patients with cardiac disease. The difference in end-tidal oxygen partial pressure from resting to anaerobic threshold (ΔPETO2) may represent predominantly peripheral factors. This study aimed to verify the prognostic significance of ΔPETO2 for major adverse cardiac and