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The treatment effect of operative intervention for flame versus scald burns in resource-limited settings Burns (IF 3.2) Pub Date : 2024-08-18 Sarah Peiffer, Linda Kayange, Selena An, Olivia Boddie, Anthony Charles, Jared Gallaher
In resource-limited environments, it is critical to triage burn patients most likely to benefit from operative intervention. This study sought to identify patients with a more significant treatment effect after operative intervention following burn injury at a tertiary burn center in Lilongwe, Malawi. This is a retrospective analysis of burn patients presenting to Kamuzu Central Hospital from 2011
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Clinical comparison study of square flap method and five-flap Z-plasty technique for correction of post-burn axillary contractures: Analysis of length gain and evaluation of functional outcome Burns (IF 3.2) Pub Date : 2024-08-17 Mahmoud A. Hifny, Ahmed Gaber Abdelmegeed
While there is no consensus on the best surgical procedure for post-burn axillary contractures, it is crucial to consider the elongation rate along the scar axis as a useful measurement index for determining the optimal surgical approach. The square flap and five flap z-plasty techniques are commonly employed scar lengthening procedures to address scar contractures in the axilla. These approaches successfully
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The added value of cultured cells in burn treatment: A systematic review Burns (IF 3.2) Pub Date : 2024-08-16 Marie Simaey, Ignace De Decker, Florian Vanlauwe, Phillip Blondeel, Stan Monstrey, Karel E.Y. Claes
Advancements in resuscitative care and burn surgery have improved survival rates after extensive burn injuries, shifting focus to enhancing the quality of survival. Conventional treatment with split-thickness skin grafts (STSG) presents limitations like donor-site morbidity, limited availability in extensive burn injuries, and hypertrophic scarring (HTS). Tissue engineering aims to address these drawbacks
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Wounds within: The hidden scars of violent care Burns (IF 3.2) Pub Date : 2024-08-15 Xin Zhang, Xiu-Hang Zhang
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Uncovering the treasure chest of burn care and research data Burns (IF 3.2) Pub Date : 2024-08-13 A. Mieras, PPM van Zuijlen, A. Pijpe
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Enhancing respiratory interventions for pediatric chest burns Burns (IF 3.2) Pub Date : 2024-08-13 Arnavaz Hajizadeh Barfejani
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Risk factors besides lamotrigine associated Stevens-Johnson Syndrome and toxic epidermal necrolysis Burns (IF 3.2) Pub Date : 2024-08-13 Kaveh Gharaei Nejad, Reyhaneh Ghadarjani
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Chemical burns secondary to detergent pods in the paediatric population: A regional 10-year review Burns (IF 3.2) Pub Date : 2024-08-11 Robyn Westerman, Karl Walsh
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Commentary on resveratrol promotes diabetic wound healing by inhibiting ferroptosis in vascular endothelial cells Burns (IF 3.2) Pub Date : 2024-08-10 Wenhao Wang, Zhengwei Huang, Xin Pan
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Interaction between long non-coding RNA and micro RNA in hypertrophic scar formation Burns (IF 3.2) Pub Date : 2024-08-10 Hojat Eftekhari
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Use of integra dermal regeneration template in burn patients: An Italian expert consensus Delphi study Burns (IF 3.2) Pub Date : 2024-08-08 Giuseppe Giudice, Rosario Ranno, Giuseppe Lombardo, Antonio Di Lonardo, Giuseppe Perniciaro, Maria Alma Posadinu, Davide Melandri, Roberto D'Alessio, Franz Baruffaldi Preis, Marcello Zamparelli, Daniela Risso, Giuseppe Minunni, Enrico Pinzauti, Stefano Merelli, Maurizio Governa, Giulio Maggio, Pasquale Tedeschi
Burn injuries pose significant challenges in healthcare, with Integra Dermal Regeneration Template (DRT) emerging as a prominent solution to enhance wound healing and recovery. Although there is no clear consensus on its technical use and application. We convened a panel of 14 burn specialists aiming to provide consensus regarding the application and usage of Integra® in managing burn wounds. Panelists
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Healing mechanism of cotton bandage loaded with PNIPAM/GO-Ag hydrogel on the deep second-degree burn wound in rats model Burns (IF 3.2) Pub Date : 2024-08-04 Ning Liu, Baoxia Xue, Wei Cheng, Yong Liu, Mei Niu, Yongzhen Yang, Shiping Yu, Li Zhang
Dressings play a crucial role in the management of burn wound. In this study, the cotton bandage was modified with the Poly (N-isopropylacrylamide) / graphite oxide/nano silver (PNIPAM/GO-Ag) hydrogel to obtain a novel dressing (PNIPAM/GO-Ag/COT). The healing effect of the PNIPAM/GO-Ag/COT dressing on deep second-degree burn wounds in rats and the changes of related inflammatory factors were explored
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Exploring the underlying mechanism by transcriptome sequencing in rats with high-voltage electrical burns and the role of iron metabolism Burns (IF 3.2) Pub Date : 2024-08-04 Jiawen Hao, Mengyuan Lu, Xuegang Zhao, Congying Li, Chenyang Ge, Jing Zhang, Lihong Tu, Qingfu Zhang
Clinically, the condition of skeletal muscle injury is the key to the process of high voltage electrical burn (HVEB) wound repair. The aim of this study was to identify the potential mechanisms and intervention targets of skeletal muscle injury after HVEB. A skeletal muscle injury model in SD rats with HVEB was made. Pathological examination and transcriptome sequencing of injured skeletal muscles
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Effect of fluid resuscitation with albumin on mortality in patients with severe burns: A nationwide inpatient data analysis Burns (IF 3.2) Pub Date : 2024-08-04 Kazuha Nakamura, Toshiaki Isogai, Hiroyuki Ohbe, Mikio Nakajima, Hiroki Matsui, Kiyohide Fushimi, Hideo Yasunaga
The present study aimed to evaluate the effect of albumin administration on mortality in patients with severe burns. We retrospectively analyzed data from the Diagnosis Procedure Combination Database, a nationwide inpatient database in Japan. We identified patients in the database aged ≥ 15 years who were admitted with severe burns (burn index ≥15) from April 2014 to March 2021. We included patients
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The impact of subdermal adipose derived stem cell injections and early excision on systemic oxidative stress and wound healing in rats with severe scald burns Burns (IF 3.2) Pub Date : 2024-08-02 Kubilay Gürünlüoğlu, Basri Satilmiş, Mehmet Gül, Muhammed Dündar, Nurcan Göktürk, Sami Akbulut, Ahmet Koç, Semra Gürünlüoğlu, Mehmet Aslan, Ezgi Karaaslan, Mehmet Akif Türköz, Çağla Güner Toplu, Hasan Ateş, Muhammed Mehdi Üremiş, İrem Nur Menevşe, Elif Kayhan Kuştepe, Seren Sari Ünal, Ebubekir Altundaş, Turan Yildiz, Tevfik Tolga Şahin, Sezai Yilmaz, Mehmet Demircan
This study aims to develop an experimental treatment model effective against oxidative stress in the acute period of severe burns and to analyze the mechanisms of healing large wound defects. Five rats, including 2 females and 3 males, were used as donors to obtain adipose-derived stem cells (ADSC) from the inguinal fat pad. The stem cells were labeled with green fluorescent protein. The study included
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Cumulative sum (CUSUM) analysis: A 10 year experience of outcome monitoring in a regional burn centre Burns (IF 3.2) Pub Date : 2024-07-31 Sofia Eriksson, Niall Martin, Sarah Smailes, Peter Dziewulski
Outcome monitoring can identify fluctuations in healthcare. Cumulative sum (CUSUM) analysis can detect when mortality deviates from expected, allowing early intervention through targeted audit. We present a 10-year experience of the prospective use of CUSUM methodology in a regional burn centre. Prospective outcome monitoring was conducted for all admissions to the intensive care unit between 2012
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Investigating the impact of patient-centered peer counseling on anxiety and pain among burn patients: A randomized controlled trial Burns (IF 3.2) Pub Date : 2024-07-31 Mohammad Rahimkhani, Ali Mohammadabadi, Mohammadreza Askari, Masoud Abdollahi
Pain and anxiety are common complications in burn patients, significantly impacting treatment effectiveness and overall patient well-being. Peer counseling, a form of patient education provided by individuals with shared experiences, may hold potential to alleviate this pain and anxiety. This study seeks to investigate the effectiveness of patient-centered education through peer counseling on background
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Swallowing impairment in older persons following burn injury: Validation of incidence and predictive factors for dysphagia Burns (IF 3.2) Pub Date : 2024-07-31 Nicola A. Clayton, Caroline M. Nicholls, Cheryl Brownlow, Justine O’Hara, Andrea C. Issler-Fisher, Oliver M. Fisher, Peter K. Maitz
Early retrospective data identify that dysphagia is common in older persons with burn injury, suggesting a rate of 47 %, and that it is associated with medical, burn, and nutritional outcomes. To prospectively (1) explore the incidence, (2) describe associations, and (3) evaluate risk factors for dysphagia in patients ≥ 75 years old hospitalised with burn injury. All patients > 75 years old admitted
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Critical appraisal of the “one-day-per-percent” rule - A register-based observational study Burns (IF 3.2) Pub Date : 2024-07-31 RL Brekke, SK Almeland, KO Hufthammer, AB Guttormsen, E. Hansson, H. Onarheim
The ”one-day-per-percent” rule states that for burn patients, one day of hospital stay can be expected for each percentage of burned body surface. This study aimed to test the rule's predictive value. The study is a register-based observational study on all burns treated in the Norwegian National Burn Center 2000–22. All children and adults admitted and actively treated in this period were included
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The acceptability of early psychological interventions for adults with appearance concerns after burns Burns (IF 3.2) Pub Date : 2024-07-31 Laura Shepherd, Fuschia Sirois, Diana Harcourt, Paul Norman, Andrew R. Thompson
Appearance concerns are common following burns. However, there is a lack of research investigating early psychological interventions for appearance concerns. This qualitative study explored the acceptability of early psychological interventions for appearance concerns after burns. Fifteen adults (nine female; 18–56 years) with appearance concerns were interviewed within three months post-burn to explore
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Promising anti-inflammatory activity of a novel designed anti-microbial peptide for wound healing Burns (IF 3.2) Pub Date : 2024-07-31 Fariba Fathi, Maryam Ghobeh, Farshad H. Shirazi, Maryam Tabarzad
Chronic wounds can develop as a result of prolonged inflammation during the healing process, which can happen due to bacterial infection. Therefore, preventing infection and controlling inflammation can accelerate wound healing. Antimicrobial peptides have different protective properties in addition to antimicrobial activity. Some of these activities include the stimulation of cytokine or chemokine
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Delayed admission to hospital with proper prehospital treatments prevents severely burned patients from sepsis in China: A retrospective study Burns (IF 3.2) Pub Date : 2024-07-31 Runzhi Huang, Yuanan Li, Shuyuan Xian, Wei Zhang, Yifan Liu, Sujie Xie, Dayuan Xu, Yushu Zhu, Hanlin Sun, Jiale Yan, Xinya Guo, Yixu Li, Jianyu Lu, Xirui Tong, Yuntao Yao, Weijin Qian, Bingnan Lu, Jiaying Shi, Xiaoyi Ding, Junqiang Li, Shichu Xiao, Shizhao Ji
Sepsis is one of the major causes of morbidity and mortality in burn patients. However, the optimal timing of admission which can minimize the probability of sepsis is still unclear. This study aims to determine the optimal time period of admission for severely burned patients and find out the possible reasons for it. 185 victims to the Kunshan factory aluminum dust explosion accident, which happened
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Butane misuse and its consequences: Unmasking the silent epidemic of burn injuries among adolescents Burns (IF 3.2) Pub Date : 2024-07-22 Kai Shi, Xin-Xin Chen, Xiu-Hang Zhang
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Enhanced healing of burn wounds by multifunctional alginate-chitosan hydrogel enclosing silymarin and zinc oxide nanoparticles Burns (IF 3.2) Pub Date : 2024-07-20 Moein Valadi, Maryam Doostan, Kamyar Khoshnevisan, Mahtab Doostan, Hassan Maleki
Multifunctional wound dressings have been applied for burn injuries to avoid complications and promote tissue regeneration. In the present study, we fabricated a natural alginate-chitosan hydrogel comprising silymarin and green-synthesized zinc oxide nanoparticles (ZnO NPs). Then, the physicochemical attributes of ZnO NPs and loaded hydrogels were analyzed. Afterward, wound healing efficacy was evaluated
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Lamotrigine Emerging as a Driver of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: An 8-Year Retrospective Study Burns (IF 3.2) Pub Date : 2024-07-20 Joshua Zev Glahn, Mariana N. Almeida, Alejandro Kochen, Olivier Noel, Viola Stogner, Henry C. Hsia, Alisa Savetamal
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) represent severe manifestations of a potentially life-threatening spectrum defined by a desquamating rash of the skin and mucous membranes. This study was prompted by the observed increase in the off-label use of lamotrigine as a causal agent in SJS/TEN in our regional burn center. A retrospective cohort of 48 patients presenting to
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Differences in burn injury knowledge among reproductive-age women attending an urban and a semi-rural hospital in Northwest Nigeria: A cross-sectional study Burns (IF 3.2) Pub Date : 2024-07-18 Godpower C. Michael, Adewale O. Ashimi, Ibrahim Aliyu, Mohammad Riyad
To assess burn injury knowledge and its predictors among reproductive-age women attending an urban and a semi-rural hospital in Northwest Nigeria A descriptive cross-sectional study It was conducted in the general and paediatric outpatient clinics of Aminu Kano Teaching Hospital in Kano (urban setting) and the general outpatient, paediatric outpatient and antenatal clinics of Federal Medical Centre
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The prevalence and predictors of reconstructive surgery in pediatric burn care Burns (IF 3.2) Pub Date : 2024-07-17 M.D. Cuijpers, A. Meij - de Vries, P.P.M. van Zuijlen, M.G.A. Baartmans, M. Nieuwenhuis, M.E. van Baar, A. Pijpe, Dutch Burn Repository Group
This study aimed to examine the prevalence and predictors of reconstructive surgery among pediatric burn patients in the Netherlands. Pediatric burn patients were identified through the Dutch Burn Repository R3. Eligibility criteria included a burn requiring hospital admission or surgical treatment at one of the Dutch burn centers in 2009–2019. First, patient, burn, and treatment characteristics were
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The relationship between job satisfaction and motivation levels of nurses working in the burn units Burns (IF 3.2) Pub Date : 2024-07-15 A. Kabuk, P. Ongün
For nurses working in specialized units such as burn units, having adequate levels of job satisfaction and motivation is crucial for enhanced productivity in order to maintain quality nursing care. A cross-sectional, descriptive, correlational design was used in the study. The study aimed to investigate the job satisfaction and motivation levels of nurses working in burn units, the relationship between
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Evaluating mechanical and biological responses of bipolymeric drug-chitosan-hydroxyapatite scaffold for wound created during sport training: Fabrication, characterization, and finite element analysis Burns (IF 3.2) Pub Date : 2024-07-14 Qihao Wang, Xiaodong Sun, Ali Basem, lbę Słabi Hussam, Sh. Baghaei, R. Rezaei
This study aims to explore the potential of a scaffold composed of drug-chitosan-hydroxyapatite (HA) in improving tissue treatment. The focus of the investigation lies in analyzing the physical and biological properties of the scaffold and evaluating its mechanical characteristics through finite element analysis. To synthesize microcapsules containing dextran-diclofenac sodium, the electrospraying
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Adaptation of a standardized self-reported cost questionnaire specific for the severe burn injury population (BI-CoPaQ) Burns (IF 3.2) Pub Date : 2024-07-11 Maria-Eugenia Espinoza-Moya, Maude Laberge, Laurianne Bélanger, Sue-Ling Chang, Thomas G. Poder, Véronique J. Moulin, Lucie Germain, Chanel Beaudoin Cloutier, Jason Robert Guertin
Severe burn injuries (SBIs) are known to pose a significant burden on patients, caregivers, and the healthcare system. Yet, scarce data on the short and long-term clinical and economic impacts of these injuries limits the development of evidence-informed strategies and policies to better care for these patients. To fill in this gap, we adapted a previously validated self-reported out-of-pocket cost
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Resveratrol promotes diabetic wound healing by inhibiting ferroptosis in vascular endothelial cells Burns (IF 3.2) Pub Date : 2024-07-11 Kui Xiao, Sisi Wang, Gang Li, Wenxin Chen, Bin Chen, Xiaojian Li
Diabetic wounds are a common complication of diabetes, with alarming disability and mortality rates. Ferroptosis plays an essential role in the occurrence and development of diabetes mellitus and its complications, suggesting that mitigating ferroptosis can be used as a potential therapeutic strategy. Resveratrol (RSV) can promote the angiogenesis of diabetic wounds, but its molecular mechanism is
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Enhancing clinical outcomes in burn and surgical intensive care units patients Burns (IF 3.2) Pub Date : 2024-07-10 Mahta Moghaddam Ahmadi, Moein Moghaddam Ahmadi
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Patient-reported scar quality in paediatric and adult burn patients: A long-term multicentre follow-up study Burns (IF 3.2) Pub Date : 2024-07-10 Jan N. Dijkshoorn, Margriet E. van Baar, Anouk Pijpe, Marianne Nieuwenhuis, Harold Goei, Cornelis H. van der Vlies, Inge Spronk
Burn scar maturation can take several years but is generally studied shortly after injury. Therefore, we investigated patient-reported scar quality up to 5–7 years post-burn. Patients with ≤ 20 % total body surface area burned completed the Patient Scale of the Patient and Observer Scar Assessment Scale (POSAS 2.0) on the same scar at three, > 18 months (median 28 months) and 5–7 years (median 63 months)
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Nanocellulose significantly reduces number of anesthetics, hospitalization and in-patient dressing changes compared to PU-Foam Dressing: A prospective cohort study in children Burns (IF 3.2) Pub Date : 2024-07-09 Miriam Renkert, Florentine Günter, Christoph Mohr, Kristina Maurer, Michaela Klinke Petrowsky, Michael Boettcher, Julia Elrod
Pediatric thermal injuries can have profound physical and psychological effects. Long-term care, including wound dressing selection, significantly impacts outcomes. This study compared treatment related variables and long-term results of bacterial nanocellulose (BNC) and polyurethane foam (PU-foam) dressings in pediatric burn care. A prospective cohort study comparing BNC (2018–2020) and PU-foam (2016–2018)
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Evaluation of emergency skin decontamination protocols in response to an acid attack (vitreolage) Burns (IF 3.2) Pub Date : 2024-07-08 H. Matar, P.R. Vuddanda, R.P. Chilcott
The incidence of “acid attacks” (vitreolage) is a global concern, with those affected often receiving lifelong medical care due to physical and psychological damage. The purpose of this study was to evaluate the effectiveness of several emergency skin decontamination approaches against concentrated (>99 %) sulphuric acid and to identify the effective window of opportunity for decontamination. The effects
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The national burden of mortality and its associated factors among burn patients in Ethiopia. A systematic review and meta-analysis Burns (IF 3.2) Pub Date : 2024-07-08 Mengistu Abebe Messelu, Nega Nigussie Abrha, Haymanot Kitaw Jemberie, Tiruye Azene Demile, Asnake Gashaw Belayneh
Despite all advances in burn prevention, treatment, acute care, and rehabilitation, burn injuries continue to cause significant mortality and disability in Ethiopia. Thus, this review and meta-analysis aimed to assess the pooled prevalence and its determinants of mortality in Ethiopia. This systematic review was conducted according to the guidelines of Preferred Reporting Items for Systematic Reviews
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The prognostic relevance of full-thickness burns on ABSI Burns (IF 3.2) Pub Date : 2024-07-06 J. Gorenflo, B. Reichert, German Burn Registry, S. Reif, I.-F. Megas, M. Billner
The Abbreviated Burn Severity Index (ABSI) by Tobiasen, which is commonly used to estimate the mortality risk of severely burned patients, calculates an additional point for the existence of full-thickness (third-degree) burns. [1] However, the score does not consider the extent of how much of the burnt body surface was affected by thirddegree burns. To understand whether there is a way to improve
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The association between neighborhood disadvantage and patient-reported outcomes in burn survivors Burns (IF 3.2) Pub Date : 2024-07-04 Arushi Biswas, Zachary H. Zamore, Zohra Aslami, Rafael Felix P. Tiongco, Ayman Ali, Carisa M. Cooney, Mark D. Fisher, Julie A. Caffrey, Sheera F. Lerman
Burns can cause long-term complications including pain and poor physical function. While neighborhood disadvantage is associated with burn severity, its effect on long-term complications has not been investigated. We hypothesized that patients from areas of higher area of deprivation index (ADI) will report poorer long-term outcomes. We linked patient data from the Burn Model System with ADI state
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Enhancing wound treatment with superoxide dismutase-loaded solid lipid nanoparticles Burns (IF 3.2) Pub Date : 2024-07-03 Hui Sun, Wei Shen, Hui-Qiong Nie, Yi Yao, Ying-Ming Ma, Zhi-Hong Ma, Hua-Jie Zhong
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Beyond skin deep: Revealing the essence of ips cell-generated skin organoids in regeneration Burns (IF 3.2) Pub Date : 2024-06-27 Yu-Xuan Zhang, Yuan Zhou, Yu-Yun Xiong, Yu-Mei Li
Various methods have been used for in vivo and in vitro skin regeneration, including stem cell therapy, tissue engineering, 3D printing, and platelet-rich plasma (PRP) injection therapy. However, these approaches are rooted in the existing knowledge of skin structures, which overlook the normal physiological processes of skin development and fall short of replicating the skin's regenerative processes
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Patient care for burn victims in Brazil: A national survey Burns (IF 3.2) Pub Date : 2024-06-24 Marco Aurelio Cruciol Rodrigues, Marcos Toshiyuki Tanita, André José Yabar Alfaro, Cintia Magalhães Carvalho Grion
To analyze, through the responses of physicians who work in burn treatment units, their demographic profiles and academic backgrounds, the structure available for patient care, the adoption of care protocols, support from medical and multidisciplinary specialties, and the main challenges faced by these professionals. Cross-sectional study of the survey type carried out from March 2020 to April 2021
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Does NexoBrid® have antimicrobial properties? Burns (IF 3.2) Pub Date : 2024-06-22 Amal Sharaf, Philip Turpin, Neil Ullyott, Preetha Muthayya
We previously published the microbial profile of burn wounds managed with NexoBrid® in Pinderfields Regional Burns Centre, Wakefield, UK. Our results showed no significant changes in bacterial colonisation in burn wounds debrided with NexoBrid®. Previous studies described the antimicrobial properties of bromelain enzyme. To date, the effects of NexoBrid® on microorganisms have not been reported. In
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Esketamine use for primary intelligent analgesia in adults with severe burns: A double-blind randomized trial with effects on analgesic efficacy, gastrointestinal function and mental state Burns (IF 3.2) Pub Date : 2024-06-22 Qiulan He, Qi Liu, Bing Liang, Xu Zhao, Wenqi Huang, Shaowei Gao, Caiyun Chen, Fei Zhou, Zhongxing Wang
Opioid consumption for analgesia in burn patients is enormous. Non-opioid analgesics for burn pain management may result in opioid sparing, reducing opioid-related adverse reactions and drug tolerance or addiction. A dual-center, randomized controlled trial assessed Esketamine for perioperative period in patients with severe [20–50 % total body surface area (TBSA)] and extensive ( 50 % TBSA) burns
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Corrigendum to “Potential antibacterial activity and healing effect of topical administration of bone marrow and adipose mesenchymal stem cells encapsulated in collagen-fibrin hydrogel scaffold on full-thickness burn wound infection caused by Pseudomonas aeruginosa” [Burns 49(8) (2023) 1944–1957] Burns (IF 3.2) Pub Date : 2024-06-21 Maryam Mirshekar, Hamed Afkhami, Shabnam Razavi, Faramarz Masjedian Jazi, Davood Darban-Sarokhalil, Elnaz Ohadi, Majid Motaghinejad, Roya Karimi
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Methodological concerns about the prediction model of mortality risk for patients with necrotizing soft tissue infections in the intensive care unit Burns (IF 3.2) Pub Date : 2024-06-21 Li Chen, Ying Xu
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Early high-volume resuscitation with crystalloid solution combined with albumin – Pragmatic advice Burns (IF 3.2) Pub Date : 2024-06-21 TS Burge
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Psychological needs of children of mothers who attempt suicide by self-immolation Burns (IF 3.2) Pub Date : 2024-06-20 Leeba Rezaie, David C. Schwebel
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Letter to the Editor regarding “Predictors of mortality following electrical and lightning injuries in Malawi: A decade of experience” Burns (IF 3.2) Pub Date : 2024-06-18 Norberto Navarrete, Juan David Rodriguez-Parra
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The association between body mass index and physical function in adult burn survivors: A Burn Model System National Database study Burns (IF 3.2) Pub Date : 2024-06-17 Alen Palackic, Victoria G. Rontoyanni, Julia Kleinhapl, Camila Franco-Mesa, Ludwik K. Branski, David N. Herndon, Jeffrey Schneider, Kimberly Roaten, Colleen M. Ryan, Karen Kowalske, Nicole Gibran, Barclay Stewart, Steven E. Wolf, Oscar E. Suman-Vejas
An area of rehabilitation research in burns is the impact of co-morbidities on disease trajectory. Obesity is a comorbidity of increasing public health concern, but its role remains controversial regarding burn injury and physical recovery. Our aim was to evaluate the association between body mass index (BMI) categories as a measure of obesity at discharge and self-reported physical function (PF) during
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The inclusion criteria and minimum dataset for burn-injured patients at the National Trauma Registry of Iran Burns (IF 3.2) Pub Date : 2024-06-13 Payman Salamati, Mohammad Reza Zafarghandi
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Inter-individual variability of aerobic capacity after rehabilitation exercise training in children with severe burn injury Burns (IF 3.2) Pub Date : 2024-06-10 Eric Rivas, Julia Kleinhapl, Oscar E. Suman-Vejas
Severe burn trauma damages resting and exercise cardiac function that may affect long term cardiovascular health. The implementation of rehabilitation exercise training (RET) soon after hospital discharge improves cardiorespiratory fitness; however, does not fully restore aerobic capacity and presents large inter-individual variability. We tested the hypothesis that the inter-individual variability
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Long-term renal function after burn-related acute kidney injury with continuous renal replacement therapy Burns (IF 3.2) Pub Date : 2024-06-06 Travis Gordon, Bader Al-Zeer, Bingyue Zhu, Alexandra Romann, Peter Neufeld, Donald Griesdale, Anthony Papp
Acute kidney injury (AKI) is a common complication of severe burn injury and is associated with significant morbidity and mortality. Continuous Renal Replacement Therapy (CRRT) is the preferred treatment for stage 3 AKI due to severe burn. This retrospective cohort study at a single institution aimed to examine the long-term renal outcomes after discharge of burn survivors who underwent CRRT during
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Utility of customized 3D compression mask with pressure sensors on facial burn scars: A single-blinded, randomized controlled trial Burns (IF 3.2) Pub Date : 2024-06-06 Seok Jin Hwang, Jisu Seo, Jeong Yeon Cha, Hyunjun Shin, Gyu Seok Kim, Young Min Cho, Zheng Hua, Hyoung Soon Youn, Cheong Hoon Seo, So Young Joo, Yoon Soo Cho
A pressure of approximately 15–25 mmHg is used for effective compression therapy to prevent and treat hypertrophic scar formation in patients with burns. However, conventional facial compression garments present challenges owing to inadequate pressure distribution in curved areas such as the cheeks, around the mouth, and the slope of the nose. This study aimed to evaluate the utility of a custom-made
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Artiss fibrin sealant for the fixation of autografts in pediatric burn care Burns (IF 3.2) Pub Date : 2024-06-06 Carolyn Reuland, Charbel Chidiac, Clint Cappiello, Erica Hodgman
Traditional fixation of autografts in the treatment of burns involves the use of sutures and staples. A novel fibrin sealant, Artiss, has been introduced as an alternate method of fixation and has shown promising safety and efficacy results in the adult population. Our study assessed the effectiveness of fibrin sealant to secure autologous split thickness skin grafts (ASTSG) in the pediatric burn population
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The minimal important change (MIC) and minimal clinically important difference (MCID) of the patient and observer scar assessment scale (POSAS) 2.0 Burns (IF 3.2) Pub Date : 2024-06-06 Catherine M. Legemate, Esther Middelkoop, Michelle E. Carrière, Paul P.M. van Zuijlen, Margriet E. van Baar, Cornelis H. van der Vlies, for the Hycon Study group
The Patient and Observer Scar Assessment Scale (POSAS) is frequently used to assess scar quality after burns. It is important to be aware of the minimal important change (MIC) and the minimal clinically important difference (MCID) to establish if a POSAS score represents a clinically relevant change or difference. The aim of this study is to explore the MIC and MCID of POSAS version 2.0. This prospective
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Superoxide dismutase-contained solid lipid nanoparticles: Formulation development and In-vivo evaluation for second-degree burn wound healing in rats Burns (IF 3.2) Pub Date : 2024-06-06 Behzad Sharif Makhmalzadeh, Siavash Khaksar Haghani Dehkordi, Anahita Rezaie, Masoud Ali Karami
Superoxide dismutase (SOD), a natural enzyme with high antioxidant activity, reduces injury and accelerates wound healing by scavenging superoxide radicals. This enzyme plays an important role in cellular defense against oxidative stress such as burn injury. The aim of this study was to load SOD into solid lipid nanoparticles for the treatment of rat burn wounds. Solid lipid nanoparticles were prepared
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Human dental pulp stem cells for burn wound healing: Potential therapeutic applications Burns (IF 3.2) Pub Date : 2024-06-02 Mohammad Vakili Ojarood, Bahar Farhadi, Hamidreza Alizadeh-Otaghvar, Seyed Mostafa Mohsenizadeh, Ramyar Farzan, Tahereh Yaghoubi
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Metformin is associated with reduced risk of mortality and morbidity in burn patients compared to insulin Burns (IF 3.2) Pub Date : 2024-05-27 Taylor G. Hallman, Georgiy Golovko, Juquan Song, Alen Palackic, Steven E. Wolf, Amina El Ayadi
The standard of care for burned patients experiencing hyperglycemia associated with the hypermetabolic response is insulin therapy. Insulin treatment predisposes burn patients to hypoglycemia, which increases morbidity and mortality. Metformin has been suggested as an alternative to insulin therapy for glycemic control in burn patients given its safety profile, but further research is warranted. This
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Raising the bar: Development and implementation of a novel positioning system for extremity burn surgery Burns (IF 3.2) Pub Date : 2024-05-14 Ronak A. Patel, Benjamin L. Cox, Ajay S. Patel, Sebastian Q. Vrouwe