-
What every intensivist should know about augmented renal clearance (ARC) J. Crit. Care (IF 3.2) Pub Date : 2024-09-10 Tim J.L. Smeets, Chantal A. Boly, John Papadopoulos, Henrik Endeman, Nicole G.M. Hunfeld
-
Correlation of venous excess ultrasound (VExUS) score to fluid responsiveness in critically ill patients J. Crit. Care (IF 3.2) Pub Date : 2024-09-07 Kyriakos K. Trigkidis, Christina Routsi, Stelios Kokkoris
-
Understanding ventilator-induced lung injury: The role of mechanical power J. Crit. Care (IF 3.2) Pub Date : 2024-09-05 Stephan von Düring MD MSc, Ken Kuljit S. Parhar MD MSc, Neill K.J. Adhikari MDCM MSc, Martin Urner MD PhD, S. Joseph Kim MD PhD, Laveena Munshi MD MSc, Kuan Liu PhD, Eddy Fan MD PhD
Mechanical ventilation stands as a life-saving intervention in the management of respiratory failure. However, it carries the risk of ventilator-induced lung injury. Despite the adoption of lung-protective ventilation strategies, including lower tidal volumes and pressure limitations, mortality rates remain high, leaving room for innovative approaches. The concept of mechanical power has emerged as
-
Practice survey on recent changes in post cardiac arrest care and temperature management in French intensive care units J. Crit. Care (IF 3.2) Pub Date : 2024-08-30 Clément Haddadi, Antoine Kimmoun, Marine Jacquier, Bruno Megarbane, Nicolas Deye, Bruno Levy
Recent guidelines for post-cardiac arrest (CA) management have undergone significant changes regarding targeted therapeutic management (TTM), transitioning from hypothermia to temperature control. We aimed to assess changes in post-CA management in French intensive care units following the new recommendations. Two declarative web surveys were conducted from March to August 2023. We compared the doctors'
-
Sustained elevation of calprotectin associates with delayed appearance of myeloid-derived suppressor cells in patients with septic shock J. Crit. Care (IF 3.2) Pub Date : 2024-08-29 Muzhda Haem Rahimi, Cécile Poussineau, Charlotte Cuerq, Martin Cour, Anne-Claire Lukaszewicz, Fabienne Venet, Guillaume Monneret
-
Preload responsiveness–guided fluid removal in mechanically ventilated patients with fluid overload: A comprehensive clinical–physiological study J. Crit. Care (IF 3.2) Pub Date : 2024-08-27 Ricardo Castro, Pablo Born, Eric Roessler, Christian Labra, Paul McNab, Sebastián Bravo, Dagoberto Soto, Eduardo Kattan, Glenn Hernández, Jan Bakker
This study investigated fluid removal strategies for critically ill patients with fluid overload on mechanical ventilation. Traditionally, a negative fluid balance (FB) is aimed for. However, this approach can have drawbacks. Here, we compared a new approach, namely removing fluids until patients become fluid responsive (FR) to the traditional empiric negative balance approach.
-
Reducing plastic waste in intensive care from longer use of intravenous administration and invasive monitoring sets: A before-and-after study J. Crit. Care (IF 3.2) Pub Date : 2024-08-24 Marc Schluep, Martijn Minheere, Michelle Baus, Stefan Machielse, Anita Donkers, Heleen Vroman
Intensive care unit (ICU) treatment carries a large environmental burden. Extending routine replacement of plastic line sets that belong to intravenous administration or invasive monitoring might lower waste from single-use plastics in ICUs. We extended the routine replacement interval of line sets from 4 to 7 days and assessed plastic waste reduction. In this single center retrospective study the
-
Influence of contrast medium on long-term renal function and outcomes in patients with septic acute kidney injury: A propensity-matched cohort study J. Crit. Care (IF 3.2) Pub Date : 2024-08-20 Jinnam Kim, Se Ju Lee, Jung Ho Kim, Jin Young Ahn, Su Jin Jeong, Jun Yong Choi, Joon-Sup Yeom, Hyung Jung Oh, Yong Eun Chung, Nam Su Ku
To investigate the relationship between contrast medium administration and long-term mortality and renal function in patients with septic acute kidney injury (AKI). We performed a retrospective, propensity-matched cohort study involving 1521 adult patients admitted with septic shock. Patients with septic AKI who underwent contrast or non-contrast CT scans were enrolled. The primary outcomes were the
-
Heliox ventilation in elderly, hypertensive ICU patients improves microcirculation: A randomized controlled study J. Crit. Care (IF 3.2) Pub Date : 2024-08-12 Lili Zhou, Jing Lin, Mingkai Zhuang, Yue Wang, Qinyong Weng, Hui Zhang
Conventional mechanical ventilation has adverse impacts on the hemodynamics of elderly, hypertensive ICU patients. Limited studies have addressed ways to ameliorate these negative effects. This study aimed to determine whether heliox ventilation could improve the hemodynamics, especially microcirculation, of elderly, hypertensive patients undergoing mechanical ventilation. Thirty-eight patients, over
-
Normalization of IL-6 levels is associated with survival in critically ill patients with COVID-19 J. Crit. Care (IF 3.2) Pub Date : 2024-08-12 Anahita Mostaghim, Neha A. Sathe, F. Linzee Mabrey, Sharon Sahi, Nick O'Connor, Eric D. Morrell, Michael Fitzpatrick, Craig H. Smith, Mark M. Wurfel, W. Conrad Liles, Pavan K. Bhatraju
-
Outcomes of continuous renal replacement therapy versus peritoneal dialysis as a renal replacement therapy modality in patients undergoing Venoarterial extracorporeal membrane oxygenation J. Crit. Care (IF 3.2) Pub Date : 2024-08-07 Peerapat Thanapongsatorn, Nisha Wanichwecharungruang, Nattachai Srisawat
The optimal modality for renal replacement therapy (RRT) in patients venoarterial extracorporeal membrane oxygenation (VA-ECMO) remains unclear. This study aimed to compare outcomes between continuous renal replacement therapy (CRRT) and peritoneal dialysis (PD) in VA-ECMO patients. This single-center retrospective study included VA-ECMO patients who developed AKI and subsequently required CRRT or
-
Continuous glucose monitoring versus conventional glucose monitoring in the ICU: A randomized controlled trial J. Crit. Care (IF 3.2) Pub Date : 2024-08-05 Chen Chu, Jian Li, XiaoDong Yang, HuiJing Zhao, ZaiXian Wu, RuoXin Xu, JianLing Gao
This study evaluated the clinical utility of continuous glucose monitoring system (CGMS) in critically ill patients. In this randomized controlled trial, we randomly assigned critically ill participants with diabetes or stress-induced hyperglycemia to the CGMS group ( = 48) or to the conventional point-of-care monitoring (POCM) group (n = 48). The glucose values and clinical outcome were compared between
-
Antisense therapy to block the Kallikrein-kinin pathway in COVID-19: The ASKCOV randomized controlled trial J. Crit. Care (IF 3.2) Pub Date : 2024-08-03 Fernando G. Zampieri, Glauco Adrieno Westphal, Maria Adelaide Dos Santos, Samara P.C. Gomes, Jackeline O. Gomes, Karina L. Negrelli, Renato H.N. Santos, Luciana M. Ishihara, Tamiris A. Miranda, Ligia N. Laranjeira, Nanci Valeis, Eliana Vieira Santucci, Vicente Cés de Souza Dantas, Otávio Gebara, Danny M. Cohn, Gustavo Buchele, Mariano Janiszewski, Flávio Geraldo de Freitas, Felipe Dal-Pizzol, Alexandre
-
Risk of complications in observational ICU admission after QT-prolonging drug intoxication J. Crit. Care (IF 3.2) Pub Date : 2024-08-02 P.M.L. Zomer, M.M. Deckers, A.J.R. De Bie Dekker, M.J.A. Kamps
-
Letter to the Editor: “Prophylactic versus restrictive platelet transfusion strategy in patients with haematological malignancies in the ICU setting, a propensity-score analysis” J. Crit. Care (IF 3.2) Pub Date : 2024-07-31 N. Motayar, T. Haigh, M. Tomberlin, T. Kurth
-
Venoarterial extracorporeal membrane oxygenation in high-risk pulmonary embolism: A narrative review J. Crit. Care (IF 3.2) Pub Date : 2024-07-29 Eugene Yuriditsky, Jan Bakker, Carlos L. Alviar, Sripal Bangalore, James M. Horowitz
Emergent reperfusion, most commonly with the administration of thrombolytic agents, is the recommended management approach for patients presenting with high-risk, or hemodynamically unstable pulmonary embolism. However, a subset of patients with a more catastrophic presentation, including refractory shock and impending or active cardiopulmonary arrest, may require immediate circulatory support. Venoarterial
-
Therapeutic plasma exchange: A promising adjunctive treatment for tuberculosis-induced Hemophagocytic Lymphohistiocytosis? J. Crit. Care (IF 3.2) Pub Date : 2024-07-26 Muhammad Ahmad, Muneeza Ijaz, Ali Israr Ahmed, Rukhsar Aftab
-
Machine learning for predicting mortality in adult critically ill patients with Sepsis: A systematic review J. Crit. Care (IF 3.2) Pub Date : 2024-07-25 Nasrin Nikravangolsefid, Swetha Reddy, Hong Hieu Truong, Mariam Charkviani, Jacob Ninan, Larry J. Prokop, Supawadee Suppadungsuk, Waryaam Singh, Kianoush B. Kashani, Juan Pablo Domecq Garces
Introduction: Various Machine Learning (ML) models have been used to predict sepsis-associated mortality. We conducted a systematic review to evaluate the methodologies employed in studies to predict mortality among patients with sepsis.
-
Fluid infusion prior to intubation or anesthesia: A meta-analysis of randomized controlled trials J. Crit. Care (IF 3.2) Pub Date : 2024-07-24 Zhenfeng Lu, Jingsheng Guo, Aiping Zhang, Lin Song, Haibin Ni
The results of current randomized controlled trials (RCTs) vary regarding the effectiveness of rehydration prior to anesthesia induction. Our objective was to determine the effectiveness of pre-induction rehydration in patients undergoing tracheal intubation or surgical procedures. This meta-analysis followed PRISMA guidelines and was registered in the INPLASY database (registration number: INPLASY2022100099)
-
Does extracorporeal cardiopulmonary resuscitation improve survival with favorable neurological outcome in out-of-hospital cardiac arrest? A systematic review and meta-analysis J. Crit. Care (IF 3.2) Pub Date : 2024-07-24 Linda Pagura, Enrico Fabris, Serena Rakar, Marco Gabrielli, Enzo Mazzaro, Gianfranco Sinagra, Davide Stolfo
Extracorporeal cardiopulmonary resuscitation (-CPR) may improve survival with favorable neurological outcome in patients with refractory out-of-hospital cardiac arrest (OHCA). Unfortunately, recent results from randomized controlled trials were inconclusive. We performed a meta-analysis to investigate the impact of -CPR on neurological outcome compared to conventional cardiopulmonary resuscitation
-
End-tidal carbon dioxide during spontaneous breathing trial to predict extubation failure: A prospective observational study J. Crit. Care (IF 3.2) Pub Date : 2024-07-19 Faten May, Nicolas de Prost, Keyvan Razazi, Guillaume Carteaux, Armand Mekontso Dessap
Despite advances in weaning protocols, extubation failure (EF) is associated with poor outcomes. Many predictors of EF have been proposed, including hypercapnia at the end of the spontaneous breathing test (SBT). However, performing arterial blood gases at the end of SBT is not routinely recommended, whereas end-tidal carbon dioxide (EtCO2) can be routinely monitored during SBT.
-
Association of second antibiotic dose delays on mortality in patients with septic shock J. Crit. Care (IF 3.2) Pub Date : 2024-07-18 Zenalabdin H. Jabir PharmD, Travis S. Grey PharmD BCPS BCCCP, Angela R. Morelli PharmD BCPS BCIDP, Brandon D. Nornhold PharmD, Jestin N. Carlson MD MS MHA, Diane V. Thompson M.S, Animesh C. Gour MD
Determine whether a delay in the administration of the second dose of antibiotics is associated with an increased risk of mortality for patients admitted with septic shock. Retrospective, observational evaluation. Regional multicenter evaluation including four institutions in western Pennsylvania. A total of 905 patients were included in this study who met the criteria for septic shock. Patients that
-
Authors response: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience” J. Crit. Care (IF 3.2) Pub Date : 2024-07-17 Ana Gaspar, Madalena Gama, Gustavo Nobre de Jesus, Sara Querido, Juliana Damas, João Oliveira, Marta Neves, Alice Santana, João Miguel Ribeiro
-
Association of early changes in arterial carbon dioxide with acute brain injury in adult patients with extracorporeal membrane oxygenation: A ten-year retrospective study in a German tertiary care hospital J. Crit. Care (IF 3.2) Pub Date : 2024-07-17 Yuanyuan Yu, Iris Lettow, Kevin Roedl, Dominik Jarczak, Hans Pinnschmidt, Hermann Reichenspurner, Alexander M. Bernhardt, Gerold Söffker, Benedikt Schrage, Markus Haar, Theresa Weber, Daniel Frings, Stefan Kluge, Marlene Fischer
To assess the association between fluctuations of arterial carbon dioxide early after start of extracorporeal membrane oxygenation (ECMO) with intracranial hemorrhage (ICH) or ischemic stroke (IS). This single-center retrospective study included patients who required ECMO for circulatory or respiratory failure between January 2011 and April 2021 and for whom a cerebral computed tomography (cCT) scan
-
Critical care management of hantavirus cardiopulmonary syndrome. A narrative review J. Crit. Care (IF 3.2) Pub Date : 2024-07-17 Rodrigo Ulloa-Morrison, Nicolas Pavez, Esteban Parra, Rene Lopez, Roberto Mondaca, Paula Fernandez, David Kraunik, Claudia Sanhueza, Sebastian Bravo, Matias Germán Cornu, Eduardo Kattan
Hantaviruses, members of the family, can cause two patterns of disease in humans, hantavirus hemorrhagic fever with renal syndrome (HFRS) and cardiopulmonary syndrome (HCPS), being the latter hegemonic on the American continent. is one of the strains that can cause HCPS and is endemic in Chile. Its transmission occurs through direct or indirect contact with infected rodents' urine, saliva, or feces
-
Indications, results and consequences of electroencephalography in neurocritical care: A retrospective study J. Crit. Care (IF 3.2) Pub Date : 2024-07-16 Wolmet E. Haksteen MD, Gulsum Z. Nasim MD, Marjolein M. Admiraal PhD, Daan C. Velseboer MD PhD, A. Fleur van Rootselaar MDPhD, Janneke Horn MD PhD
Electrocencephalography (EEG) is a tool to assess cerebral cortical activity. We investigated the indications and results of routine EEG recordings in neurocritical care patients and corresponding changes in anti-seizure medication (ASM). This was a single-center, retrospective cohort study. We included all adult Intensive Care Unit (ICU) patients with severe acute brain injury who received a routine
-
Letter to the Editor: “Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience” J. Crit. Care (IF 3.2) Pub Date : 2024-07-15 Lingxiang Ran, Rui Zhao, Guangmo Hu
-
Authors response: “Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis” J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Aashish Kumar, Ra'eesa Doola, Amanda Zahumensky, Arif Shaikh, Alexis Tabah, Kevin B. Laupland, Mahesh Ramanan
-
Letter to the Editor: “Association between elevated lactate and clinical outcomes in adults with diabetic ketoacidosis” J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Syeda Dua Azhar, Yusra Saleem, Aimen Waqar Khan
-
Letter to the editor: “How a positive fluid balance develops in acute kidney injury: A binational, observational study” J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Alejandro Úbeda-Iglesias, Dra. Irene Fernández-Burgos
-
Changes in left ventricular-arterial coupling during resuscitation are associated with mortality in patients with septic shock - A post-hoc analysis of a randomized trial J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Xiaoyang Zhou, Jianneng Pan, Hua Wang, Zhaojun Xu, Bixin Chen, Caibao Hu
-
Establishing consensus on patient- and family-centered care in adult intensive care units: A Delphi survey J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Søs Bohart MSc. RN, Anne Højager Nielsen RN PhD, Jette Led Sørensen MD PhD MMEd, Anne Sofie Andreasen MD PhD, Tina Waldau MD MPG PhD, Ann Merete Møller MD, Thordis Thomsen RN PhD
To establish consensus between intensive care unit (ICU) experts on concrete patient- and family-centered care statements for adult patients and relatives in the ICU. We did a three-round Delphi survey with a panel of ICU health care professionals from 23 ICUs in Denmark. In round 1, participants answered 20 open-ended questions, based on existing evidence. Analysis of their responses generated close-ended
-
One-year outcomes in COVID-19 and non-COVID-19 intensive care unit survivors J. Crit. Care (IF 3.2) Pub Date : 2024-07-14 Hidde Heesakkers, Johannes G. van der Hoeven, Stijn Corsten, Inge Janssen, Esther Ewalds, Koen S. Simons, Maaike de Blauw, Thijs C.D. Rettig, Crétien Jacobs, Susanne van Santen M.D, Arjen J.C. Slooter, Margaretha C.E. van der Woude, Marieke Zegers, Mark van den Boogaard
To determine differences in one-year multi-domain health outcomes in COVID-19 and non-COVID-19 intensive care unit (ICU) survivors. Adult ICU survivors treated for COVID-19 were compared to a control group consisting of survivors admitted for respiratory distress due to other causes, i.e. non-COVID-19 ARDS or pneumonia. Occurrence of physical (frailty, fatigue, physical symptoms), mental (anxiety,
-
Enhancing Sepsis prognosis: Integrating social determinants and demographic variables into a comprehensive model for critically ill patients J. Crit. Care (IF 3.2) Pub Date : 2024-07-11 Elie Sarraf, Alireza Vafaei Sadr, Vida Abedi, Anthony S. Bonavia
The Sequential Organ Failure Assessment (SOFA) score monitors organ failure and defines sepsis but may not fully capture factors influencing sepsis mortality. Socioeconomic and demographic impacts on sepsis outcomes have been highlighted recently. To evaluate the prognostic value of SOFA scores against demographic and social health determinants for predicting sepsis mortality in critically ill patients
-
High PEEP/low FiO2 ventilation is associated with lower mortality in COVID–19 J. Crit. Care (IF 3.2) Pub Date : 2024-07-11 Robin L. Goossen, Relin van Vliet, Lieuwe D.J. Bos, Laura A. Buiteman-Kruizinga, Markus W. Hollman, Sheila N. Myatra, Ary Serpa Neto, Peter E. Spronk, Meta C.E. van der Woude, David M.P. van Meenen, Frederique Paulus, Marcus J. Schultz, for the PRoVAcT-COVID investigators, S. Ahuja, J.P. van Akkeren, A.G. Algera, C.K. Algoe, R.B. van Amstel, A. Artigas, E. Aydeniz, M. Bailey, A.E. van den Berg, P.
The positive end–expiratory pressure (PEEP) strategy in patients with coronavirus 2019 (COVID–19) acute respiratory distress syndrome (ARDS) remains debated. Most studies originate from the initial waves of the pandemic. Here we aimed to assess the impact of high PEEP/low FiO ventilation on outcomes during the second wave in the Netherlands. Retrospective observational study of invasively ventilated
-
Authors reply: “How a positive fluid balance develops in acute kidney injury: A binational, observational study” J. Crit. Care (IF 3.2) Pub Date : 2024-07-04 Kyle C. White, Kevin B. Laupland, Rinaldo Bellomo
-
The effect of high-dose selenium on mortality and postoperative organ dysfunction in post-cardiotomy cardiogenic shock patients supported with mechanical circulatory support – A post-hoc analysis of the SUSTAIN CSX trial J. Crit. Care (IF 3.2) Pub Date : 2024-07-02 Sascha Ott, Ellen Dresen, Zheng Yii Lee, Lukas M. Müller-Wirtz, Livia Procopiuc, Elyad Ekrami, Leonard Pitts, Nicolas Hellner, Daniel Catena, Georg Daniel Duerr, Maria Wittmann, Reiner M. Waeschle, Gunnar Elke, Benjamin O'Brien, Daren K. Heyland, Christian Stoppe
Cardiac surgery, post-cardiotomy cardiogenic shock (PCCS), and temporary mechanical circulatory support (tMCS) provoke substantial inflammation. We therefore investigated whether a selenium-based, anti-inflammatory strategy would benefit PCCS patients treated with tMCS in a post-hoc analysis of the sustain CSX trial. Post-hoc analysis of patients receiving tMCS for PCCS in the Sustain CSX trial, which
-
Impact of AKI on metabolic compensation for respiratory acidosis in ICU patients with AECOPD J. Crit. Care (IF 3.2) Pub Date : 2024-06-26 Florian Marcy MD, Katharina Goettfried, Philipp Enghard MD PhD, Sophie K. Piper PhD, Julius Valentin Kunz MD, Tim Schroeder MD
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) can result in severe respiratory acidosis. Metabolic compensation is primarily achieved by renal retention of bicarbonate. The extent to which acute kidney injury (AKI) impairs the kidney's capacity to compensate for respiratory acidosis remains unclear. This retrospective analysis covers clinical data between January 2009 and December
-
Letter to the Editor: “Development of a machine learning model for prediction of the duration of unassisted spontaneous breathing in patients during prolonged weaning from mechanical ventilation” J. Crit. Care (IF 3.2) Pub Date : 2024-06-25 Rashid Nadeem, Atif Altafuddin Ahmad
-
The ratio of parasternal intercostal muscle-thickening fraction-to-diaphragm thickening fraction for predicting weaning failure J. Crit. Care (IF 3.2) Pub Date : 2024-06-22 Li Peng, Hongshan Kang, Hairong Chang, Yue Sun, Yuanyuan Zhao, Heling Zhao
Diaphragm dysfunction is associated with weaning outcomes in mechanical ventilation patients, in the case of diaphragm dysfunction, the accessory respiratory muscles would be recruited. The main purpose of this study is to explore the performance of parasternal intercostal muscle thickening fraction in relation to diaphragmatic thickening fraction ratio (TFic/TFdi) for predicting weaning outcomes,
-
Letter to the Editor: “Different ventilation intensities among various categories of patients ventilated for reasons other than ARDS – A pooled analysis of 4 observational studies.” J. Crit. Care (IF 3.2) Pub Date : 2024-06-21 Lorenzo Schiavoni, Alessia Mattei, Alessandro Ruggiero, Alessandro Strumia
-
Authors’ response: “Development of a machine learning model for prediction of the duration of unassisted spontaneous breathing in patients during prolonged weaning from mechanical ventilation” J. Crit. Care (IF 3.2) Pub Date : 2024-06-21 Sebastian Johannes Fritsch, Morris Riedel, Gernot Marx, Johannes Bickenbach, Andreas Schuppert
-
Authors' response: ‘Different ventilation intensities amongst various categories of patients ventilated for reasons other than ARDS––A pooled analysis of 4 observational studies’ J. Crit. Care (IF 3.2) Pub Date : 2024-06-20 Simon Corrado Serafini, Marcus J. Schultz
-
Sepsis phenotypes in the era of individualized medicine J. Crit. Care (IF 3.2) Pub Date : 2024-06-19 Elio Antonucci, Marc Leone
-
Outcomes of extracorporeal blood purification with oXiris® membrane in critically ill patients: A systematic review and meta-analysis J. Crit. Care (IF 3.2) Pub Date : 2024-06-19 Li Ying Siew, Zheng-Yii Lee, Nor'azim Mohd Yunos, Rafidah Atan, Matthew Edward Cove, Nuttha Lumlertgul, Nattachai Srisawat, M. Shahnaz Hasan
To evaluate the efficacy of the novel oXiris® membrane in critically ill adult patients. We systematically searched MEDLINE, EMBASE, and CENTRAL from inception to 01/06/2023 for relevant randomised controlled trials (RCTs) and non-randomised studies of intervention (NRSI). The primary outcome was overall mortality. Random effect meta-analyses were conducted in RevMan 5.4.1. Study quality was evaluated
-
Behind the scenes: Key lessons learned from the RELIEVE-AKI clinical trial J. Crit. Care (IF 3.2) Pub Date : 2024-06-15 Nasrin Nikravangolsefid MD MPH, Supawadee Suppadungsuk M.D, Waryaam Singh M.B.B.S, Paul M. Palevsky MD, Raghavan Murugan MD. M.S, Kianoush B. Kashani MD. M.S
Continuous kidney replacement therapy (CKRT) is commonly used to manage critically ill patients with severe acute kidney injury. While recent trials focused on the correct dosing and timing of CKRT, our understanding regarding the optimum dose of net ultrafiltration is limited to retrospective data. The Restrictive versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury
-
Long-term survival of traumatic brain injury and intra-cerebral haemorrhage patients: A multicentric observational cohort J. Crit. Care (IF 3.2) Pub Date : 2024-06-14 E. Dantan, Y. Foucher, J. Simon-Pimmel, M. Léger, M. Campfort, S. Lasocki, K. Lakhal, M. Bouras, A. Roquilly, R. Cinotti, for the AtlanREA study group
Mortality is often assessed during ICU stay and early after, but rarely at later stage. We aimed to compare the long-term mortality between TBI and ICH patients. From an observational cohort, we studied 580 TBI patients and 435 ICH patients, admitted from January 2013 to February 2021 in 3 ICUs and alive at 7-days post-ICU discharge. We performed a Lasso-penalized Cox survival analysis. We estimated
-
Driving pressure during routine ventilation in the ICU: Is the ICU-team as driven as they should be? J. Crit. Care (IF 3.2) Pub Date : 2024-06-13 Renee Post-Spenkelink, Marleen Flim, Ingrid D. van Iperen, Marnix Kuindersma, Peter E. Spronk
-
The impact of frailty on survival times up to one year among patients admitted to ICU with in-hospital cardiac arrest J. Crit. Care (IF 3.2) Pub Date : 2024-06-11 Ryo Ueno MD, Mallikarjuna Ponnapa Reddy MBBS, Daryl Jones PhD, David Pilcher MBBS, Ashwin Subramaniam MMed
In-hospital cardiac arrest (IHCA) is a serious medical emergency. When IHCA occurs in patients with frailty, short-term survival is poor. However, the impact of frailty on long-term survival is unknown. We performed a retrospective multicentre study of all critically ill adult (age ≥ 16 years) patients admitted to Australian intensive care units (ICU) between 1st January 2018 to 31st March 2022. We
-
Letter to the Editor: “Efficacy and safety of corticosteroids for the treatment of community-acquired pneumonia: A systematic review and meta-analysis of randomized controlled trials” J. Crit. Care (IF 3.2) Pub Date : 2024-06-01 Shan-Chi Chang M.D., Enoch Kang M.A., Kee-Hsin Chen Ph.D.
-
Authors response: "Efficacy and safety of corticosteroids for the treatment of community-acquired pneumonia: A systematic review and meta-analysis of randomized controlled trials." J. Crit. Care (IF 3.2) Pub Date : 2024-05-31 Huzaifa Ahmad Cheema, Tamas Szakmany
-
Letter to the editor: “Efficacy and safety of corticosteroids for the treatment of community-acquired pneumonia: A systematic review and meta-analysis of randomized controlled trials” J. Crit. Care (IF 3.2) Pub Date : 2024-05-29 Ling Zhang MD, Chang'e Wei MM
-
Effectiveness of early high-flow nasal oxygen therapy after extubation of patients in the intensive care unit J. Crit. Care (IF 3.2) Pub Date : 2024-05-28 Atsushi Ishihara, Hideshi Okada, Teruki Mori, Takashi Yoshizane, Kentaro Morishita, Takuji Yamamoto, Izumi Toyoda, Toshiyuki Noda
This study aimed to evaluate the impact of early high-flow nasal oxygen (HFNO) therapy initiation using a pre-determined respiratory rate‑oxygenation (ROX) index on reducing reintubation rates and duration of intensive care unit (ICU) stay in post-extubated patients. We enrolled a total of 145 extubated patients (mean age: 67.1 ± 12.9 years; sex: 96 male and 49 female; acute physiology and chronic
-
What every intensivist should know about…Systolic arterial pressure targets in shock J. Crit. Care (IF 3.2) Pub Date : 2024-05-28 Eugene Yuriditsky MD, Jan Bakker MD PhD
-
Prophylactic versus restrictive platelet transfusion strategy in patients with haematological malignancies in the ICU setting, a propensity-score analysis J. Crit. Care (IF 3.2) Pub Date : 2024-05-27 Jean-Baptiste Berenger, Colombe Saillard, Antoine Sannini, Luca Servan, Frederic Gonzalez, Marion Faucher, Jean-Manuel de Guibert, Marie-Anne Hospital, Magali Bisbal, Laurent Chow-Chine, Djamel Mokart
Prophylactic platelet transfusions (PT) aim to reduce bleeding. We assessed whether restrictive PT compared to prophylactic strategy could apply in ICU. We conducted a retrospective monocentric study including patients >18 yo with haematological malignancy admitted to the ICU with thrombocytopenia <20 G/L between 2018 and 2021. Patients were classified in 2 groups according transfusion strategy applied
-
Corrigendum to “An update on ICU outcomes in patients after CAR-T therapy: A four-year tertiary UK centre experience” [J Crit Care. 2024 Apr:80:154511]. J. Crit. Care (IF 3.2) Pub Date : 2024-05-25 Lily Scourfield, Tasneem Pirani, Neeraj Singh, Rohit Saha, Andrea Kuhnl, Robin Sanderson, Victoria Metaxa
-
Prevalence and prognostic relevance of invasive fungal disease during veno-arterial ECMO: A retrospective single-center study J. Crit. Care (IF 3.2) Pub Date : 2024-05-25 Jens M. Poth, Mathias Schmandt, Jens-Christian Schewe, Felix Lehmann, Stefan Kreyer, Zaki Kohistani, Farhad Bakhtiary, Gunnar Hischebeth, Christian Putensen, Johannes Weller, Stefan F. Ehrentraut
-
Urea to creatinine ratio as a predictor of persistent critical illness J. Crit. Care (IF 3.2) Pub Date : 2024-05-22 Liran Statlender, Tzippy Shochat, Eyal Robinson, Guy Fishman, Moran Hellerman-Itzhaki, Itai Bendavid, Pierre Singer, Ilya Kagan
Persistent critical illness (PCI) is a syndrome in which the acute presenting problem has been stabilized, but the patient's clinical state does not allow ICU discharge. The burden associated with PCI is substantial. The most obvious marker of PCI is prolonged ICU length of stay (LOS), usually greater than 10 days. Urea to Creatinine ratio (UCr) has been suggested as an early marker of PCI development
-
Association between comorbidities at ICU admission and post-Sepsis physical impairment: A retrospective cohort study J. Crit. Care (IF 3.2) Pub Date : 2024-05-22 Seibi Kobara, Ryohei Yamamoto, Milad G. Rad, Jocelyn R. Grunwell, Nao Hikota, Yoshihiro Uzawa, Yoshiro Hayashi, Craig M. Coopersmith, Rishikesan Kamaleswaran
Few studies have measured the association between pre-existing comorbidities and post-sepsis physical impairment. The study aimed to estimate the risk of physical impairment at hospital discharge among sepsis patients, adjusting for pre-existing physical impairment prior to ICU admission and in-hospital mortality. We analyzed all consecutive adult patients admitted to an ICU in a tertiary community
-
The interaction of net ultrafiltration rate with urine output and fluid balance after continuous renal replacement therapy initiation: A multi-Centre study. J. Crit. Care (IF 3.2) Pub Date : 2024-05-20 Kyle White, Kevin B. Laupland, Rinaldo Bellomo, Ary Serpa-Neto
During continuous renal replacement therapy (CRRT), a high net ultrafiltration rate (NUF) may worsen the decrease in urine output (UO) associated with starting CRRT. However, fluid balance (FB) may modulate this association. We aimed to examine the relationship between NUF, UO and FB at the start of CRRT. A retrospective cohort study of 1030 CRRT-treated patients admitted to two tertiary ICUs. Median