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Evaluation of Myocarditis with a Free-breathing 3D Isotropic Whole-Heart Joint T1 and T2 Mapping Sequence. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-19 Alina Hua,Carlos Velasco,Camila Munoz,Giorgia Milotta,Anastasia Fotaki,Filippo Bosio,Inka Granlund,Agata Sularz,Amedeo Chiribiri,Karl P Kunze,Rene Botnar,Claudia Prieto,Tevfik F Ismail
BACKGROUND The diagnosis of myocarditis by CMR requires the use of T2 and T1 weighted imaging, ideally incorporating parametric mapping. Current 2D mapping sequences are acquired sequentially and involve multiple breath-holds resulting in prolonged scan times and anisotropic image resolution. We developed an isotropic free-breathing 3D whole-heart sequence which allows simultaneous T1 and T2 mapping
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iNav-based, Automated Coronary Magnetic Resonance Angiography for the Detection of Coronary Artery Stenosis (iNav-AUTO CMRA). J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-16 Gregory Wood,Reza Hajhosseiny,Alexandra Uglebjerg Pedersen,Simon Littlewood,Tina Juul Hansen,Radhouene Neji,Karl P Kunze,Jens Wetzl,Bjarne Linde Nørgaard,Jesper Møller Jensen,Michael Maeng,Per Lav Madsen,Niels Vejlstrup,Claudia Prieto,René M Botnar,Won Yong Kim
BACKGROUND Coronary computed tomography angiography (CCTA) is recommended as the first line diagnostic imaging modality in low to intermediate risk individuals suspected of stable coronary artery disease (CAD). However, CCTA exposes patients to ionising radiation and potentially nephrotoxic contrast agents. Invasive coronary angiography (ICA) is the gold-standard investigation to guide coronary revascularisation
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Automated biventricular quantification in patients with repaired tetralogy of Fallot using a 3D deep learning segmentation model. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-11 Sofie Tilborghs,Tiffany Liang,Stavroula Raptis,Ayako Ishikita,Werner Budts,Tom Dresselaers,Jan Bogaert,Frederik Maes,Rachel M Wald,Alexander Van De Bruaene
BACKGROUND Deep learning is the state-of-the-art approach for automated segmentation of the left ventricle (LV) and right ventricle (RV) in cardiac magnetic resonance (CMR) images. However, these models have been mostly trained and validated using CMR datasets of structurally normal hearts or cases with acquired cardiac disease, and are therefore not well-suited to handle cases with congenital cardiac
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Hyperpolarized [1-13C]pyruvate Magnetic Resonance Imaging Identifies Metabolic Phenotypes in Patients with Heart Failure. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-11 Steen Hylgaard Joergensen,Esben Soevsoe S Hansen,Nikolaj Bøgh,Lotte Bonde Bertelsen,Rasmus Stilling Tougaard,Peter Bisgaard Staehr,Christoffer Laustsen,Henrik Wiggers
BACKGROUND Hyperpolarized [1-13C]pyruvate magnetic resonance imaging (HP MRI) visualizes key steps in myocardial metabolism. The present study aimed to examine patients with heart (HF) using HP MRI. METHODS A cross-sectional study of patients with HF and healthy controls using HP MRI. Metabolic imaging was obtained using a cardiac-gated spectral-spatial excitation with spiral read-out acquisition.
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Practice Patterns of Cardiovascular Magnetic Resonance Use in the Diagnosis of Pediatric Myocarditis: A Survey-Based Study. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-11 Hannah M Jacobs,Jonathan H Soslow,Matthew D Cornicelli,Shae A Merves,Ruchira Garg,Mehul D Patel,Arpit Agarwal,Nilanjana Misra,Michael P DiLorenzo,M Jay Campbell,Jeremy Steele,Jennifer Co-Vu,Joshua D Robinson,Simon Lee,Jason N Johnson
BACKGROUND Cardiovascular magnetic resonance (CMR) is used to diagnose myocarditis in adults and children based on the original Lake Louise Criteria (LLC) and more recently the revised LLC. The major change included in the revised LLC was the incorporation of parametric mapping, which significantly increases the sensitivity and specificity of diagnosis. Subsequently, scientific statements have recommended
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Free-Breathing Non-Contrast T1ρ Dispersion MRI of Myocardial Interstitial Fibrosis in Comparison with Extracellular Volume Fraction. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-06 Qinfang Miao,Sha Hua,Yiwen Gong,Zhenfeng Lyu,Pengfang Qian,Chun Liu,Wei Jin,Peng Hu,Haikun Qi
BACKGROUND Myocardial fibrosis is a common feature in various cardiac diseases. It causes adverse cardiac remodeling and is associated with poor clinical outcomes. Late gadolinium enhancement (LGE) and extracellular volume fraction (ECV) are the standard MRI techniques for detecting focal and diffuse myocardial fibrosis. However, these contrast-enhanced techniques require the administration of gadolinium
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Accelerated Chemical Shift Encoded Cardiac MRI with Use of Resolution Enhancement Network. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-09-05 Manuel A Morales,Scott Johnson,Patrick Pierce,Reza Nezafat
BACKGROUND Cardiovascular magnetic resonance (CMR) chemical shift encoding (CSE) enables myocardial fat imaging. We sought to develop a deep learning network (FastCSE) to accelerate CSE. METHODS FastCSE was built on a super-resolution generative adversarial network extended to enhance complex-valued image sharpness. FastCSE enhances each echo image independently before water-fat separation. FastCSE
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Assessing Aortic Motion with Automated 3D Cine Balanced SSFP MRI Segmentation. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-30 Renske Merton,Daan Bosshardt,Gustav J Strijkers,Aart J Nederveen,Eric M Schrauben,Pim van Ooij
PURPOSE To apply free-running three-dimensional (3D) cine balanced steady state free precession (bSSFP) CMR framework in combination with AI segmentations to quantify time-resolved aortic displacement, diameter and diameter change. METHODS In this prospective study, we implemented a free-running 3D cine bSSFP sequence with scan time of about 4minutes facilitated by pseudo-spiral Cartesian undersampling
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Impact of valve-sparing aortic root replacement on aortic fluid dynamics and biomechanics in patients with syndromic heritable thoracic aortic disease. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-28 Lydia Dux-Santoy,Aroa Ruiz-Muñoz,Andrea Guala,Laura Galian-Gay,Rubén Fernandez-Galera,Filipa Valente,Guillem Casas,Ruperto Oliveró,Marta Ferrer-Cornet,Mireia Bragulat-Arévalo,Alejandro Carrasco-Poves,Juan Garrido-Oliver,Alberto Morales-Galán,Kevin M Johnson,Oliver Wieben,Ignacio Ferreira-González,Arturo Evangelista,Jose Rodriguez-Palomares,Gisela Teixidó-Turà
OBJECTIVES Patients with syndromic heritable thoracic aortic diseases (sHTAD) who underwent prophylactic aortic root replacement are at high risk of distal aortic events, but the underlying mechanisms are poorly understood. This prospective, longitudinal study aims to assess the impact of valve-sparing aortic root replacement (VSARR) on aortic fluid dynamics and biomechanics in these patients, and
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Comparison of diagnostic algorithms in clinically suspected viral myocarditis: agreement between cardiac magnetic resonance, endomyocardial biopsy and troponin T. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-25 Hafisyatul Zainal,Andreas Rolf,Hui Zhou,Moises Vasquez,Felicitas Escher,Till Keller,Mariuca Vasa-Nicotera,Andreas M Zeiher,Heinz-Peter Schultheiss,Eike Nagel,Valentina O Puntmann
AIMS Myocardial inflammation is increasingly detected non-invasively by tissue mapping with cardiovascular magnetic resonance (CMR). Intraindividual agreement with endomyocardial biopsy (EMB) or marker of myocardial injury, high-sensitive troponin (hs-cTnT) in patients with clinically suspected viral myocarditis not understood. METHODS AND RESULTS Prospective multicentre study of consecutive patients
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Removed: "Kiosk 8Q-FA-03-Gedatolisib Associated Acute Myocarditis in a Patient with Breast Adenocarcinoma" [Journal of Cardiovascular Magnetic Resonance 26 (2024) 100856]. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-23 Mohamad Khattab,Jennifer Kwan,Deya Alkhatib,Miles Shen,Sagar Desai,Emmanuel Akintoye,Steffen Huber,Lauren Baldassarre
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Comparison of dual-bolus versus dual-sequence techniques for determining myocardial blood flow and myocardial perfusion reserve by cardiac magnetic resonance stress perfusion: From the Automated Quantitative analysis of myocardial perfusion cardiac Magnetic Resonance Consortium. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-16 Emily Yin Sing Chong,Haonan Wang,Kwan Ho Gordon Leung,Paul Kim,Yuko Tada,Tsun Hei Sin,Chun Ka Wong,Kwong Yue Eric Chan,Chor Cheung Frankie Tam,Mitchel Benovoy,Andrew E Arai,Victor Goh,Martin A Janich,Amit R Patel,Ming-Yen Ng
BACKGROUND Quantitative stress cardiac magnetic resonance (CMR) can be performed using the dual-sequence (DS) technique or dual-bolus (DB) method. It is unknown if DS and DB produce similar results for myocardial blood flow (MBF) and myocardial perfusion reserve (MPR). The study objective is to investigate if there are any differences between DB- and DS-derived MBF and MPR. METHODS Retrospective observational
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Comprehensive sex-specific and age-dependent analysis of 4D-flow MRI assessed aortic blood flow-related parameters in normal subjects using single-vendor MR systems and single-vendor software. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-12 Mitch J F G Ramaekers,Bastiaan J C Te Kiefte,Bouke P Adriaans,Joe F Juffermans,Hans C van Assen,Bjorn Winkens,Joachim E Wildberger,Hildo J Lamb,Simon Schalla,Jos J M Westenberg
BACKGROUND Aortic blood flow characterization by 4D flow MRI is increasingly performed in aneurysm research. A limited number of studies have established normal values that can aid the recognition of abnormal flow at an early stage. This study aims to establish additional sex-specific and age-dependent reference values for flow-related parameters in a large cohort of healthy adults. METHODS 212 volunteers
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Role of endogenous T1ρ and its dispersion imaging in differential diagnosis of cardiac amyloidosis. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-08 Keyan Wang,Yong Zhang,Wenbo Zhang,Hongrui Jin,Jing An,Jingliang Cheng,Jie Zheng
BACKGROUND Cardiovascular magnetic resonance (CMR) has demonstrated excellent performance in the diagnosis of cardiac amyloidosis (CA). However, misdiagnosis occasionally occurs because the morphological and functional features of CA are non-specific. This study was performed to determine the value of non-contrast CMR T1ρ in the diagnosis of CA. METHODS This prospective study included 45 patients with
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Impact of training data composition on the generalizability of convolutional neural network aortic cross-section segmentation in four-dimensional magnetic resonance flow imaging. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-08 Chiara Manini,Markus Hüllebrand,Lars Walczak,Sarah Nordmeyer,Lina Jarmatz,Titus Kuehne,Heiko Stern,Christian Meierhofer,Andreas Harloff,Jennifer Erley,Sebastian Kelle,Peter Bannas,Ralf Felix Trauzeddel,Jeanette Schulz-Menger,Anja Hennemuth
BACKGROUND Four-dimensional cardiovascular magnetic resonance flow imaging (4D flow CMR) plays an important role in assessing cardiovascular diseases. However, the manual or semi-automatic segmentation of aortic vessel boundaries in 4D flow data introduces variability and limits the reproducibility of aortic hemodynamics visualization and quantitative flow-related parameter computation. This paper
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Unfinished debate: Why IPH-based metrics are still needed-An Editorial for "Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: the Plaque At RISK (PARISK) study". J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-08 Chun Yuan,Gador Canton,Thomas S Hatsukami
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Cardiovascular magnetic resonance feature tracking derived strain analysis can predict return to training following exertional heatstroke. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-06 Jun Zhang,Song Luo,Li Qi,Shutian Xu,Dongna Yi,Yue Jiang,Xiang Kong,Tongyuan Liu,Weiqiang Dou,Jun Cai,Long Jiang Zhang
BACKGROUND Exertional heatstroke (EHS) is increasingly common in young trained soldiers. However, prognostic markers in EHS patients remain unclear. The objective of this study was to evaluate cardiovascular magnetic resonance (CMR) feature tracking derived left ventricle (LV) strain as a biomarker for return to training (RTT) in trained soldiers with EHS. METHODS Trained soldiers (participants) with
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Interval changes in four-dimensional flow-derived in vivo hemodynamics stratify aortic growth in type B aortic dissection patients. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-02 Joshua Engel,Ozden Kilinc,Elizabeth Weiss,Justin Baraboo,Christopher Mehta,Andrew Hoel,S Chris Malaisrie,Michael Markl,Bradley D Allen
BACKGROUND Aortic diameter growth in type B aortic dissection (TBAD) is associated with progressive aortic dilation, resulting in increased mortality in patients with both de novo TBAD (dnTBAD) and residual dissection after type A dissection repair (rTAAD). Preemptive thoracic endovascular aortic repair may improve mortality in patients with TBAD, although it is unclear which patients may benefit most
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Respiratory-resolved 5D Flow MRI: in-vivo validation and respiratory dependent flow changes in healthy volunteers and patients with congenital heart disease. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-02 Elizabeth K Weiss,Justin Baraboo,Cynthia K Rigsby,Joshua D Robinson,Liliana Ma,Mariana B L Falcão,Christopher W Roy,Matthias Stuber,Michael Markl
BACKGROUND This study aimed to validate respiratory-resolved 5D flow MRI against real-time 2D phase contrast MRI, assess the impact of number of respiratory states, and measure the impact of respiration on hemodynamics in congenital heart disease (CHD) patients. METHODS Respiratory-resolved 5D flow MRI derived net and peak flow measurements were compared to real-time 2D phase contrast MRI derived measurements
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Occult coronary microvascular dysfunction and ischemic heart disease in patients with diabetes and heart failure. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-02 Noor Sharrack,Louise A E Brown,Jonathan Farley,Ali Wahab,Nicholas Jex,Sharmaine Thirunavukarasu,Amrit Chowdhary,Miroslawa Gorecka,Wasim Javed,Hui Xue,Eylem Levelt,Erica Dall'Armellina,Peter Kellman,Pankaj Garg,John P Greenwood,Sven Plein,Peter P Swoboda
BACKGROUND Patients with diabetes mellitus (DM) and heart failure (HF) have worse outcomes than normoglycemic HF patients. Cardiovascular magnetic resonance (CMR) can identify ischemic heart disease (IHD) and quantify coronary microvascular dysfunction (CMD) using myocardial perfusion reserve (MPR). We aimed to quantify the extent of silent IHD and CMD in patients with DM presenting with HF. METHODS
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Accelerated myocardial fibrosis in young to middle-aged patients with hypertrophic cardiomyopathy. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-02 Shiro Nakamori,Ethan J Rowin,Jennifer Rodriguez,Long H Ngo,Warren J Manning,Martin Maron,Reza Nezafat
BACKGROUND The extent of late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) in patients with hypertrophic cardiomyopathy (HCM) is associated with an increased risk of sudden cardiac death events. However, the clinical significance of age-specific longitudinal changes in LGE is not well characterized in HCM. We sought to assess whether the risk of LGE progression diverges between
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Regional Aortic Wall Shear Stress Increases over Time in Patients with a Bicuspid Aortic Valve. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-01 Savine C S Minderhoud,Aïmane Arrouby,Allard T van den Hoven,Lidia R Bons,Raluca G Chelu,Isabella Kardys,Dimitris Rizopoulos,Suze-Anne Korteland,Annemien E van den Bosch,Ricardo P J Budde,Jolien W Roos-Hesselink,Jolanda J Wentzel,Alexander Hirsch
BACKGROUND Aortic wall shear stress (WSS) is a known predictor of ascending aortic growth in patients with a bicuspid aortic valve (BAV). The aim of this study was to study regional WSS and changes over time in BAV patients. METHODS BAV patients and age-matched healthy controls underwent 4D flow CMR. Regional, peak systolic ascending aortic WSS, aortic valve function, aortic stiffness measures and
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In-vivo Assessment of Myocardial Calcium Uptake Using Manganese-Enhanced MRI in Aortic Stenosis. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-08-01 Abhishek Dattani,Saadia Aslam,Gaurav S Gulsin,Aseel Alfuhied,Trisha Singh,Shruti S Joshi,Lucy E Kershaw,David E Newby,Gerry P McCann,Anvesha Singh
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Late gadolinium enhancement and the diagnosis of arrhythmogenic right ventricular cardiomyopathy. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-31 David A Bluemke
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Clinical utility of a rapid two-dimensional balanced steady-state free precession sequence with deep learning reconstruction. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-28 Katerina Eyre,Moezedin Javad Rafiee,Margherita Leo,Junjie Ma,Elizabeth Hillier,Negin Amini,Josephine Pressacco,Martin A Janich,Xucheng Zhu,Matthias G Friedrich,Michael Chetrit
BACKGROUND Cardiovascular magnetic resonance (CMR) cine imaging is still limited by long acquisition times. This study evaluated the clinical utility of an accelerated two-dimensional (2D) cine sequence with deep learning reconstruction (Sonic DL) to decrease acquisition time without compromising quantitative volumetry or image quality. METHODS A sub-study using 16 participants was performed using
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Automating quality control in cardiac magnetic resonance: Artificial intelligence for discriminative assessment of planning and motion artifacts and real-time reacquisition guidance. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-28 Hoi C Cheung,Kavitha Vimalesvaran,Sameer Zaman,Michalis Michaelides,Matthew J Shun-Shin,Darrel P Francis,Graham D Cole,James P Howard
BACKGROUND Accurate measurements from cardiovascular magnetic resonance (CMR) images require precise positioning of scan planes and elimination of motion artifacts from arrhythmia or breathing. Unidentified or incorrectly managed artifacts degrade image quality, invalidate clinical measurements, and decrease diagnostic confidence. Currently, radiographers must manually inspect each acquired image to
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Generative Pre-trained Transformer 4 analysis of cardiovascular magnetic resonance reports in suspected myocarditis: A multicenter study. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-28 Kenan Kaya,Carsten Gietzen,Robert Hahnfeldt,Maher Zoubi,Tilman Emrich,Moritz C Halfmann,Malte Maria Sieren,Yannic Elser,Patrick Krumm,Jan M Brendel,Konstantin Nikolaou,Nina Haag,Jan Borggrefe,Ricarda von Krüchten,Katharina Müller-Peltzer,Constantin Ehrengut,Timm Denecke,Andreas Hagendorff,Lukas Goertz,Roman J Gertz,Alexander Christian Bunck,David Maintz,Thorsten Persigehl,Simon Lennartz,Julian A Luetkens
BACKGROUND Diagnosing myocarditis relies on multimodal data, including cardiovascular magnetic resonance (CMR), clinical symptoms, and blood values. The correct interpretation and integration of CMR findings require radiological expertise and knowledge. We aimed to investigate the performance of Generative Pre-trained Transformer 4 (GPT-4), a large language model, for report-based medical decision-making
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Reduced response to regadenoson with increased weight: an artificial intelligence based quantitative myocardial perfusion study. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-25 E Androulakis,G Georgiopoulos,A Azzu,E Surkova,A Bakula,P Papagkikas,A Briasoulis,R De Silva,P Kellman,D J Pennell,F Alpendurada
BACKGROUND There is conflicting evidence regarding the response to a fixed dose of regadenoson in patients with high body weight. The aim of this study was to evaluate the effectiveness of regadenoson in patients with varying body weights using novel quantitative CMR perfusion parameters in addition to standard clinical markers. METHODS Consecutive patients with typical angina and/or risk factors for
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Free-breathing three-dimensional simultaneous myocardial T1 and T2 mapping based on multi-parametric SAturation-recovery and Variable-flip-Angle. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-24 Dongyue Si,Rui Guo,Lan Cheng,Xiangchuang Kong,Daniel A Herzka,Haiyan Ding
BACKGROUND Quantitative myocardial tissue characterization with T1 and T2 parametric mapping can provide an accurate and complete assessment of tissue abnormalities across a broad range of cardiomyopathies. However, current clinical T1 and T2 mapping tools rely predominantly on two-dimensional (2D) breath-hold sequences. Clinical adoption of three-dimensional (3D) techniques is limited by long scan
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Society for Cardiovascular Magnetic Resonance Guidelines for Reporting Cardiovascular Magnetic Resonance Examinations in Patients with Congenital Heart Disease. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-23 Lars Grosse-Wortmann,Rachel Wald,Israel Valverde,Emanuela Lsangiacomo-Buechel,Karen Ordovas,Francesca Raimondi,Sonya Babu-Narayan,Rajesh Krishnamurthy,Deane Yim,Rahul H Rathod
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Remote myocardial fibrosis predicts adverse outcome in patients with myocardial infarction on clinical cardiovascular magnetic resonance imaging. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-23 Nicholas Black,Joshua Bradley,Erik B Schelbert,Laura J Bonnett,Gavin A Lewis,Jakub Lagan,Christopher Orsborne,Pamela F Brown,Fardad Soltani,Fredrika Fröjdh,Martin Ugander,Timothy C Wong,Miho Fukui,Joao L Cavalcante,Josephine H Naish,Simon G Williams,Theresa McDonagh,Matthias Schmitt,Christopher A Miller
BACKGROUND Heart failure (HF) most commonly occurs in patients who have had a myocardial infarction (MI), but factors other than MI size may be deterministic. Fibrosis of myocardium remote from the MI is associated with adverse remodeling. We aimed to 1) investigate the association between remote myocardial fibrosis, measured using cardiovascular magnetic resonance (CMR) extracellular volume fraction
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Can cardiovascular magnetic resonance enhance our understanding of coronary involvement in immunoglobulin subclass 4-related disease? J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-21 Tevfik F Ismail
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Identifying high-risk Fontan phenotypes using K-means clustering of cardiac magnetic resonance-based dyssynchrony metrics. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-14 Addison Gearhart,Sunakshi Bassi,Rahul H Rathod,Rebecca S Beroukhim,Stuart Lipsitz,Maxwell P Gold,David M Harrild,Audrey Dionne,Sunil J Ghelani
BACKGROUND Individuals with a Fontan circulation encompass a heterogeneous group with adverse outcomes linked to ventricular dilation, dysfunction, and dyssynchrony. The purpose of this study was to assess if unsupervised machine learning cluster analysis of cardiovascular magnetic resonance (CMR)-derived dyssynchrony metrics can separate ventricles in the Fontan circulation from normal control left
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Regional variability of cardiovascular magnetic resonance access and utilization in the United States. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-11 Jennifer M Li,David R Ho,Nazia Husain,Robert W Biederman,J Paul Finn,Anthon R Fuisz,Ibrahim M Saeed,Kim-Lien Nguyen
BACKGROUND Clinical guidelines and scientific data increasingly support the appropriate use of cardiovascular magnetic resonance (CMR) . The extent of CMR adoption across the United States (US) remains unclear. This observational analysis aims to capture CMR practice patterns in the US. METHODS Commissioned reports from the Society for Cardiovascular Magnetic Resonance (SCMR), pre-existing survey data
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Diagnostic value of late gadolinium enhancement at cardiovascular magnetic resonance to distinguish arrhythmogenic right ventricular cardiomyopathy from differentials. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-08 Lian Y Rekker,Steven A Muller,Alessio Gasperetti,Mimount Bourfiss,Marish I F J Oerlemans,Maarten J Cramer,Stefan L Zimmerman,Dennis Dooijes,Hanke Schalkx,Pim van der Harst,Cynthia A James,J Peter van Tintelen,Marco Guglielmo,Birgitta K Velthuis,Anneline S J M Te Riele
BACKGROUND While late gadolinium enhancement (LGE) is proposed as a diagnostic criterion for arrhythmogenic right ventricular cardiomyopathy (ARVC), the potential of LGE to distinguish ARVC from differentials remains unknown. We aimed to assess the diagnostic value of LGE for ARVC diagnosis. METHODS We included 132 subjects (60% male, 47 ± 11 years) who had undergone cardiac magnetic resonance imaging
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The Society for Cardiovascular Magnetic Resonance Registry at 150,000. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-04 Matthew S Tong,Jeremy A Slivnick,Behzad Sharif,Han W Kim,Alistair A Young,Lilia M Sierra-Galan,Kanae Mukai,Afshin Farzaneh-Far,Sadeer Al-Kindi,Angel T Chan,George Dibu,Michael D Elliott,Vanessa M Ferreira,John Grizzard,Sebastian Kelle,Simon Lee,Maan Malahfji,Steffen E Petersen,Venkateshwar Polsani,Olga H Toro-Salazar,Kamran A Shaikh,Chetan Shenoy,Monvadi B Srichai,Jadranka Stojanovska,Qian Tao,Janet
BACKGROUND Cardiovascular magnetic resonance (CMR) is increasingly utilized to evaluate expanding cardiovascular conditions. The Society for Cardiovascular Magnetic Resonance (SCMR) Registry is a central repository for real-world clinical data to support cardiovascular research, including those relating to outcomes, quality improvement, and machine learning. The SCMR Registry is built on a regulatory-compliant
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Prognostic value of global longitudinal strain in patients with preserved left ventricular systolic function: A cardiac magnetic resonance real-world study. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-04 Preeyaporn Janwetchasil,Ahthit Yindeengam,Rungroj Krittayaphong
BACKGROUND Myocardial strain is a more sensitive parameter for cardiac function evaluation than left ventricular ejection fraction (LVEF). This study aimed to assess the predictive value of left ventricular global longitudinal strain (LV-GLS) by feature tracking-cardiac magnetic resonance (FT-CMR) imaging in patients with known or suspected coronary artery disease (CAD) with preserved left ventricular
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Mitral annulus disjunction in consecutive patients undergoing cardiovascular magnetic resonance: Where is the boundary between normality and disease? J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-04 Stefano Figliozzi,Kamil Stankowski,Lara Tondi,Federica Catapano,Mauro Gitto,Costanza Lisi,Sara Bombace,Marzia Olivieri,Francesco Cannata,Fabio Fazzari,Renato Maria Bragato,Georgios Georgiopoulos,Pier-Giorgio Masci,Lorenzo Monti,Gianluigi Condorelli,Marco Francone
BACKGROUND The presence of mitral annulus disjunction (MAD) has been considered a high-risk feature for sudden cardiac death based on selected study populations. We aimed to assess the prevalence of MAD in consecutive patients undergoing clinically indicated cardiovascular magnetic resonance (CMR), its association with ventricular arrhythmias, mitral valve prolapse (MVP), and other CMR features. METHODS
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Prognostic value of myocardial deformation parameters for outcome prediction in tetralogy of Fallot. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-01 Subin K Thomas,Romina DSouza,Kate Hanneman,Gauri R Karur,Christian Houbois,Ayako Ishikita,Luigia D'Errico,Isaac Begun,Ming-Yen Ng,Rachel M Wald
BACKGROUND The prognostic value of myocardial deformation parameters in adults with repaired tetralogy of Fallot (rTOF) has not been well-elucidated. We therefore aimed to explore myocardial deformation parameters for outcome prediction in adults with rTOF using cardiovascular magnetic resonance imaging (CMR). METHODS Adults with rTOF and at least moderate pulmonary regurgitation were identified from
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Double aortic arch: a comparison of fetal cardiovascular magnetic resonance, postnatal computed tomography and surgical findings. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-07-01 Milou P M van Poppel,David F A Lloyd,Johannes K Steinweg,Sujeev Mathur,James Wong,Vita Zidere,Simone Speggiorin,Haran Jogeesvaran,Reza Razavi,John M Simpson,Kuberan Pushparajah,Trisha V Vigneswaran
BACKGROUND In double aortic arch (DAA), one of the arches can demonstrate atretic portions postnatally, leading to diagnostic uncertainty due to overlap with isolated right aortic arch (RAA) variants. The main objective of this study is to demonstrate the morphological evolution of different DAA phenotypes from prenatal to postnatal life using three-dimensional (3D) fetal cardiac magnetic resonance
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The effects of field strength on stimulated echo and motion-compensated spin-echo diffusion tensor cardiovascular magnetic resonance sequences. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-06-25 Andrew D Scott,Ke Wen,Yaqing Luo,Jiahao Huang,Simon Gover,Rajkumar Soundarajan,Pedro F Ferreira,Dudley J Pennell,Sonia Nielles-Vallespin
BACKGROUND In-vivo diffusion tensor cardiovascular magnetic resonance (DT-CMR) is an emerging technique for microstructural tissue characterization in the myocardium. Most studies are performed at 3T, where higher signal-to-noise ratio (SNR) should benefit this signal-starved method. However, a few studies have suggested that DT-CMR is possible at 1.5T, where echo planar imaging artifacts may be less
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Improving the efficiency and accuracy of cardiovascular magnetic resonance with artificial intelligence-review of evidence and proposition of a roadmap to clinical translation. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-06-22 Qiang Zhang,Anastasia Fotaki,Sona Ghadimi,Yu Wang,Mariya Doneva,Jens Wetzl,Jana G Delfino,Declan P O'Regan,Claudia Prieto,Frederick H Epstein
BACKGROUND Cardiovascular magnetic resonance (CMR) is an important imaging modality for the assessment of heart disease; however, limitations of CMR include long exam times and high complexity compared to other cardiac imaging modalities. Recently advancements in artificial intelligence (AI) technology have shown great potential to address many CMR limitations. While the developments are remarkable
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Thoracic duct drainage patterns in heterotaxy. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-06-21 Daniel A Castellanos,Emily M Bucholz,Katherine Bai,Jesse J Esch,David Hoganson,Stephen P Sanders,Raja Shaikh,Sunil J Ghelani,David N Schidlow
BACKGROUND Disordered lymphatic drainage is common in congenital heart diseases (CHD), but thoracic duct (TD) drainage patterns in heterotaxy have not been described in detail. This study sought to describe terminal TD sidedness in heterotaxy and its associations with other anatomic variables. METHODS This was a retrospective, single-center study of patients with heterotaxy who underwent cardiovascular
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Signal intensity and volume of carotid intraplaque hemorrhage on magnetic resonance imaging and the risk of ipsilateral cerebrovascular events: The Plaque At RISK (PARISK) study. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-06-13 Kelly P H Nies,Mueez Aizaz,Dianne H K van Dam-Nolen,Timothy C D Goring,Tobien A H C M L Schreuder,Narender P van Orshoven,Alida A Postma,Daniel Bos,Jeroen Hendrikse,Paul Nederkoorn,Rob van der Geest,Robert J van Oostenbrugge,Werner H Mess,M Eline Kooi
BACKGROUND The Plaque At RISK (PARISK) study demonstrated that patients with a carotid plaque with intraplaque hemorrhage (IPH) have an increased risk of recurrent ipsilateral ischemic cerebrovascular events. It was previously reported that symptomatic carotid plaques with IPH showed higher IPH signal intensity ratios (SIR) and larger IPH volumes than asymptomatic plaques. We explored whether IPH SIR
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Trajectory correction enables free-running chemical shift encoded imaging for accurate cardiac proton-density fat fraction quantification at 3T. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-06-13 Pierre Daudé,Thomas Troalen,Adèle L C Mackowiak,Emilien Royer,Davide Piccini,Jérôme Yerly,Josef Pfeuffer,Frank Kober,Sylviane Confort Gouny,Monique Bernard,Matthias Stuber,Jessica A M Bastiaansen,Stanislas Rapacchi
BACKGROUND Metabolic diseases can negatively alter epicardial fat accumulation and composition, which can be probed using quantitative cardiac chemical shift encoded (CSE) cardiovascular magnetic resonance (CMR) by mapping proton-density fat fraction (PDFF). To obtain motion-resolved high-resolution PDFF maps, we proposed a free-running cardiac CSE-CMR framework at 3T. To employ faster bipolar readout
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Coronary artery wall contrast enhancement imaging impact on disease activity assessment in IgG4-RD: a direct marker of coronary involvement. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-05-31 Yaqi Du,Shuang Ding,Ce Li,Yun Bai,Xinrui Wang,Debiao Li,Yibin Xie,Guoguang Fan,Lian-Ming Wu,Guan Wang
BACKGROUND Coronary artery wall contrast enhancement (CE) has been applied to non-invasive visualization of changes to the coronary artery wall in systemic lupus erythematosus (SLE). This study investigated the feasibility of quantifying CE to detect coronary involvement in IgG4-related disease (IgG4-RD), as well as the influence on disease activity assessment. METHODS A total of 93 subjects (31 IgG4-RD;
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Equilibrium phase contrast-enhanced magnetic resonance angiography of the thoracic aorta and heart using balanced T1 relaxation-enhanced steady-state. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-05-27 Robert R Edelman,Onural Ozturk,Amit Pursnani,Senthil Balasubramanian,Nondas Leloudas,Ioannis Koktzoglou
BACKGROUND Three-dimensional (3D) contrast-enhanced magnetic resonance angiography (CEMRA) is routinely used for vascular evaluation. With existing techniques for CEMRA, diagnostic image quality is only obtained during the first pass of the contrast agent or shortly thereafter, whereas angiographic quality tends to be poor when imaging is delayed to the equilibrium phase. We hypothesized that prolonged
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Using diffusion tensor imaging to depict myocardial changes after matured pluripotent stem cell-derived cardiomyocyte transplantation. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-05-23 Moses P Cook,Wahiba Dhahri,Michael A Laflamme,Nilesh R Ghugre,Graham A Wright
BACKGROUND Novel treatment strategies are needed to improve the structure and function of the myocardium post-infarction. In vitro-matured pluripotent stem cell-derived cardiomyocytes (PSC-CMs) have been shown to be a promising regenerative strategy. We hypothesized that mature PSC-CMs will have anisotropic structure and improved cell alignment when compared to immature PSC-CMs using cardiovascular
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Dispelling concerns: the mild nature of coronavirus disease 2019 vaccine-related myocarditis. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-05-08 Zahra Raisi-Estabragh
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REMOVED: Gedatolisib Associated Acute Myocarditis in a Patient with Breast Adenocarcinoma. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-04-15 Mohamad Khattab,Jennifer Kwan,Deya Alkhatib,Miles Shen,Sagar Desai,Emmanuel Akintoye,Steffen Huber,Lauren Baldassarre
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Editorial Commentary: Generative Pre-trained Transformer 4 (GPT4) makes cardiovascular magnetic resonance reports easy to understand. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-04-06 Imon Banerjee,Amara Tariq,Chieh-Ju Chao
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Diastolic function assessment with four-dimensional flow cardiovascular magnetic resonance using automatic deep learning E/A ratio analysis. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-30 Federica Viola,Mariana Bustamante,Ann Bolger,Jan Engvall,Tino Ebbers
BACKGROUND Diastolic left ventricular (LV) dysfunction is a powerful contributor to the symptoms and prognosis of patients with heart failure. In patients with depressed LV systolic function, the E/A ratio, the ratio between the peak early (E) and the peak late (A) transmitral flow velocity, is the first step to defining the grade of diastolic dysfunction. Doppler echocardiography (echo) is the preferred
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Quality assurance of late gadolinium enhancement cardiac magnetic resonance images: a deep learning classifier for confidence in the presence or absence of abnormality with potential to prompt real-time image optimization. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-24 Sameer Zaman,Kavitha Vimalesvaran,Digby Chappell,Marta Varela,Nicholas S Peters,Hunain Shiwani,Kristopher D Knott,Rhodri H Davies,James C Moon,Anil A Bharath,Nick Wf Linton,Darrel P Francis,Graham D Cole,James P Howard
BACKGROUND Late gadolinium enhancement (LGE) of the myocardium has significant diagnostic and prognostic implications, with even small areas of enhancement being important. Distinguishing between definitely normal and definitely abnormal LGE images is usually straightforward, but diagnostic uncertainty arises when reporters are not sure whether the observed LGE is genuine or not. This uncertainty might
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Design and implementation of multicenter pediatric and congenital studies with cardiovascular magnetic resonance: Big data in smaller bodies. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-23 Michael P DiLorenzo,Simon Lee,Rahul H Rathod,Francesca Raimondi,Kanwal M Farooqi,Supriya S Jain,Margaret M Samyn,Tiffanie R Johnson,Laura J Olivieri,Mark A Fogel,Wyman W Lai,Pierangelo Renella,Andrew J Powell,Sujatha Buddhe,Caitlin Stafford,Jason N Johnson,Willem A Helbing,Kuberan Pushparajah,Inga Voges,Vivek Muthurangu,Kimberley G Miles,Gerald Greil,Colin J McMahon,Timothy C Slesnick,Brian M Fonseca
Cardiovascular magnetic resonance (CMR) has become the reference standard for quantitative and qualitative assessment of ventricular function, blood flow, and myocardial tissue characterization. There is a preponderance of large CMR studies and registries in adults; However, similarly powered studies are lacking for the pediatric and congenital heart disease (PCHD) population. To date, most CMR studies
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A motion-corrected deep-learning reconstruction framework for accelerating whole-heart magnetic resonance imaging in patients with congenital heart disease. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-22 Andrew Phair,Anastasia Fotaki,Lina Felsner,Thomas J Fletcher,Haikun Qi,René M Botnar,Claudia Prieto
BACKGROUND Cardiovascular magnetic resonance (CMR) is an important imaging modality for the assessment and management of adult patients with congenital heart disease (CHD). However, conventional techniques for three-dimensional (3D) whole-heart acquisition involve long and unpredictable scan times and methods that accelerate scans via k-space undersampling often rely on long iterative reconstructions
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Cardiovascular magnetic resonance reference values of right ventricular volumetric variables in patients with hypoplastic left heart syndrome. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-16 Andrik Ballenberger,Amke Caliebe,Sylvia Krupickova,Anselm Uebing,Dominik Daniel Gabbert,Inga Voges
BACKGROUND Cardiovascular magnetic resonance (CMR) has established itself as the gold standard for serial assessment of systemic right ventricular (RV) performance but due to the lack of standardized RV reference values for hypoplastic left heart syndrome (HLHS) patients, the interpretation of RV volumetric data in HLHS remains difficult. Therefore, this study aimed to close this gap by providing CMR
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Intra-bin correction and inter-bin compensation of respiratory motion in free-running five-dimensional whole-heart magnetic resonance imaging. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-16 Christopher W Roy,Bastien Milani,Jérôme Yerly,Salim Si-Mohamed,Ludovica Romanin,Aurélien Bustin,Estelle Tenisch,Tobias Rutz,Milan Prsa,Matthias Stuber
BACKGROUND Free-running cardiac and respiratory motion-resolved whole-heart five-dimensional (5D) cardiovascular magnetic resonance (CMR) can reduce scan planning and provide a means of evaluating respiratory-driven changes in clinical parameters of interest. However, respiratory-resolved imaging can be limited by user-defined parameters which create trade-offs between residual artifact and motion
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Cardiovascular magnetic resonance imaging and clinical follow-up in patients with clinically suspected myocarditis after COVID-19 vaccination. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-11 Norain Talib,Matteo Fronza,Constantin Arndt Marschner,Paaladinesh Thavendiranathan,Gauri Rani Karur,Kate Hanneman
BACKGROUND The purpose of this study was to evaluate cardiovascular magnetic resonance (CMR) findings and their relationship to longer-term clinical outcomes in patients with suspected myocarditis following coronavirus disease 2019 (COVID-19) vaccination. METHODS Consecutive adult patients who underwent clinically indicated CMR for evaluation of suspected myocarditis following messenger ribonucleic
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Cardiovascular magnetic resonance characterization of myocardial tissue injury in a miniature swine model of cancer therapy-related cardiovascular toxicity. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-07 Kei Nakata,Selcuk Kucukseymen,Xiaoying Cai,Tuyen Yankama,Jennifer Rodriguez,Eiryu Sai,Patrick Pierce,Long Ngo,Shiro Nakamori,Nadine Tung,Warren J Manning,Reza Nezafat
BACKGROUND Left ventricular ejection fraction (LVEF) is the most commonly clinically used imaging parameter for assessing cancer therapy-related cardiac dysfunction (CTRCD). However, LVEF declines may occur late, after substantial injury. This study sought to investigate cardiovascular magnetic resonance (CMR) imaging markers of subclinical cardiac injury in a miniature swine model. METHODS Female
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Generative Pre-trained Transformer 4 makes cardiovascular magnetic resonance reports easy to understand. J. Cardiovasc. Magn. Reson. (IF 4.2) Pub Date : 2024-03-07 Babak Salam,Dmitrij Kravchenko,Sebastian Nowak,Alois M Sprinkart,Leonie Weinhold,Anna Odenthal,Narine Mesropyan,Leon M Bischoff,Ulrike Attenberger,Daniel L Kuetting,Julian A Luetkens,Alexander Isaak
BACKGROUND Patients are increasingly using Generative Pre-trained Transformer 4 (GPT-4) to better understand their own radiology findings. PURPOSE To evaluate the performance of GPT-4 in transforming cardiovascular magnetic resonance (CMR) reports into text that is comprehensible to medical laypersons. METHODS ChatGPT with GPT-4 architecture was used to generate three different explained versions of