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Assessing the applicability of obstetrical randomized controlled trials in real-world practices J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-03-03 Anthony M. Vintzileos, Cande V. Ananth
This article examines the applicability of obstetrical randomized controlled trials (RCTs) in the real-world and proposes a classification of the value of these trials based on their potential for ...
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Evaluation of the current situation and quality of neonatal hearing screening from hearing screening practitioners’ perspective: a cross-sectional study J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-02-18 Hongli Lan, Maojie Liu, Chao Huang, Jing Ren, Yu Huang, Fan Jiang, Dan Lai
In recent years, neonatal hearing screening (NHS) has gained rapid traction in both developed and developing nations. However, the efficacy of these efforts depends on comprehensive standardization...
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Effects of uterine Doppler on midbrain growth and cortical development in late onset fetal growth restricted fetuses: a prospective cross-sectional study J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-02-19 Ilenia Mappa, Maria Chiara Marra, Chiara Patelli, Jia Li Angela Lu, Francesco D’Antonio, Giuseppe Rizzo
To investigate midbrain growth, including corpus callusum (CC), cerebellar vermis (CV) and cortical development in late fetal growth restriction (FGR) depending on uterine artery (UtA) Pulsatility ...
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Predicting the risks and recognizing the signs: a two-year prospective population-based study on pregnant women with uterine rupture in The Netherlands J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-02-13 E. M. Overtoom, T. N. Huynh, A. N. Rosman, J. J. Zwart, T. P. Schaap, T. E. Vogelvang, T. van den Akker, K. W. M. Bloemenkamp
To estimate the incidence of uterine rupture in the Netherlands and evaluate risk indicators prelabour and during labor of women with adverse maternal and/or perinatal outcome.This is a population-...
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Relationship between serum NLRP3 along with its effector molecules and pregnancy outcomes in women with hyperglycemia J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-02-13 Ning Han, Zili Yuan, Hongyang Zhao, Xinyuan Chang, Yingying Chen, Miao Zhang, Yizhan Wang
The study aims to investigate the levels of serum NLRP3 along with its effector molecules (Caspase-1, IL-1β, and IL-18) in the mid-pregnancy in pregnant women with hyperglycemia, and explore the re...
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Co-existing chronic hypertension and hypertensive disorders of pregnancy and associated adverse pregnancy outcomes J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-30 Lena C. Sweeney, Lisbet S. Lundsberg, Jennifer F. Culhane, Caitlin Partridge, Moeun Son
Chronic hypertension (CHTN) causes vascular damage and resistance in the pregnant person and malperfusion in the placenta which may worsen the endothelial dysfunction of hypertensive disorders of p...
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Physical activity changes and influencing factors among Chinese pregnant women: a longitudinal study J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-23 Le Zhang, Jinlan Piao, Wei Zhang, Ningning Liu, Xuesong Zhang, Yu Shen, Ying Jin, Fangfang Wang, Suwen Feng
Participating in physical activity during pregnancy has benefited a lot from maternal and child health. However, there are few longitudinal studies describing activity patterns and related factors ...
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Allostatic load in early pregnancy and sleep-disordered breathing J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-22 Amir J. Lueth, Amanda A. Allshouse, Robert M. Silver, Marquis S. Hawkins, William A. Grobman, Susan Redline, Phyllis Zee, Shalini Manchada, Grace Pien
To assess the association between allostatic load in early pregnancy and sleep-disordered breathing (SDB) during pregnancy.High allostatic load in the first trimester was defined as ≥ 4 of 12 bioma...
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A mitochondrial regulator protein, MNRR1, is elevated in the maternal blood of women with preeclampsia J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-14 Manaphat Suksai, Roberto Romero, Mariachiara Bosco, Francesca Gotsch, Eunjung Jung, Piya Chaemsaithong, Adi L. Tarca, Dereje W. Gudicha, Nardhy Gomez-Lopez, Marcia Arenas-Hernandez, Arun Meyyazhagan, Lawrence I. Grossman, Siddhesh Aras, Tinnakorn Chaiworapongsa
Preeclampsia, one of the most serious obstetric complications, is a heterogenous disorder resulting from different pathologic processes. However, placental oxidative stress and an anti-angiogenic s...
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Upregulation of hepatic nuclear receptors in extremely preterm ovine fetuses undergoing artificial placenta therapy J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-09 Hideyuki Ikeda, Shimpei Watanabe, Shinichi Sato, Erin L. Fee, Sean W. D. Carter, Yusaku Kumagai, Tsukasa Takahashi, Shinichi Kawamura, Takushi Hanita, Sebastian E. Illanes, Mahesh A. Choolani, Masatoshi Saito, Atsuo Kikuchi, Matthew W. Kemp, Haruo Usuda
Extremely preterm infants have low Nuclear Receptor (NR) expression in their developing hepatobiliary systems, as they rely on the placenta and maternal liver for compensation. NRs play a crucial r...
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Fibrinogen as a potential diagnostic marker for prediction and evaluation of postpartum hemorrhage: a retrospective study J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2024-01-07 Yanke Zou, Yixiao Jiang, Dawei Zhu, Ling Liu, Xiuhui Zheng, Xing Gu, Changxiao Huang, Li Li
To investigate whether prenatal fibrinogen (FIB) or other related factors could be utilized to evaluate the risk of postpartum hemorrhage (PPH).A retrospective study was conducted in a database fro...
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Association of pre-/early pregnancy high blood pressure and pregnancy outcomes: a systemic review and meta-analysis J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-27 Ming Jin, Xiaowen Liu, Xiaojing Liu, Yaxian Wu, Yali Zhang, Le Zhang, Zhiwen Li, Rongwei Ye, Nan Li
Maternal high blood pressure (BP) was associated with adverse pregnancy outcomes. This study aimed to synthesize evidence on the association between high BP prior to or in early pregnancy with mate...
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Association between first-trimester ultrasound imaging of eccentric implantation and retained placenta J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-27 Shili Su, Xuejian Mu, Mei Xue, Wenjing Zhang, Ping Liu, Lanxiang Pu, Ling Wang
To evaluate first-trimester ultrasound imaging of eccentric implantation in predicting the probability of retained placenta.A total of 61 cases with gestational sac eccentrically implanted in first...
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Fetal congenital talipes equinovarus: genomic abnormalities and obstetric follow-up results J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-27 Meiying Cai, Jiansong Lin, Yanting Que, Liangpu Xu, Na Lin, Hailong Huang
The etiology of congenital talipes equinovarus (CTEV) is unknown, and the relationship between chromosome microdeletion/microduplication and fetal CTEV is rarely reported. In this study, we retrosp...
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Neonatal hypernatremic dehydration in breastfed neonates: a prospective study unmasking the influences of breastfeeding practices and early weight monitoring J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-27 Ishani Arora, Hemant Juneja, Heena Bhandekar, Manju Chandankhede
Introduction: Hypernatremic dehydration in neonates is an uncommon but serious reason for re-hospitalization, especially in exclusively breastfed neonates. The aim was to study the incidence, assoc...
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Serotype distribution, antimicrobial resistance, and molecular characterization of group B Streptococcus isolates from Chinese pregnant woman J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-20 Yifei Chen, Lin Liu, Jing Liu, Tongzhen Ji, Yang Gao, Dongmei Yang, Mohan Zhao, Yanhong Zhai, Zheng Cao
This study was aimed to investigate the serotypes, antibiotic susceptibilities, and multi-locus sequence type (MLST) profiles of group B Streptococcus (GBS) in the Beijing area.Lower vaginal and re...
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A meta-analysis of metformin and insulin on maternal outcome and neonatal outcome in patients with gestational diabetes mellitus J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-12-20 Rui Wu, Qingqing Zhang, Zuojing Li
The use of metformin for treating gestational diabetes mellitus (GDM) remains controversial because it can pass through the placenta. This meta-analysis aimed to compare the effects of metformin an...
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Impact of advanced maternal age on neonatal morbidity: a systematic review. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-28 Inês Rodrigues,Henrique Soares,Gustavo Rocha,Inês Azevedo
OBJECTIVE This systematic review aimed to understand the impact of advanced maternal age (AMA) on the neonatal morbidity, based on the available scientific evidence. METHODS A systematic search was conducted on 22 November 2021, using the PubMed and Scopus databases to identify studies that compared the morbidity of neonates delivered to AMA mothers with that of neonates delivered to non-AMA mothers
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Antibiotic administration reduced intra-amniotic inflammation 7 days after preterm premature rupture of the membranes with intra-amniotic infection. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-28 Masazumi Ikeda,Yuko Oshima,Keisuke Tsumura,Kanako Gondo,Takeshi Ono,Yutaka Kozuma,Yukiko Nakura,Itaru Yanagihara,Makoto Nomiyama,Masatoshi Yokoyama
OBJECTIVE Intra-amniotic infections increase the risk of preterm delivery and short- and long-term fetal morbidity; however, no consensus exists on the choice of antimicrobial agents as treatment for these infections. We aimed to examine the efficacy of intravenous administration of sulbactam/ampicillin (SBT/ABPC) and azithromycin (AZM) for intra-amniotic infection in patients with preterm premature
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Maternal and fetal outcomes of intraplacental choriocarcinoma complicated by fetomaternal hemorrhage: a systematic review. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-27 Guglielmo Stabile,Roberta Marie Gentile,Stefania Carlucci,Tamara Stampalija,Stefania Biffi,Giulia Oletto,Maurizio Guido,Matteo Bruno
INTRODUCTION Intraplacental choriocarcinoma is a gestational trophoblastic neoplasia located within the placenta. Due to the usual silent presentation, more than half of the cases are diagnosed incidentally. It has been demonstrated that this pathology is linked to feto-maternal hemorrhage (FMH), stillbirth, and intrauterine growth restriction. The aim of our review was to establish if there are recurrent
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Intended delivery mode and neonatal outcomes in pregnancies with fetal growth restriction. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-27 Maria J Rodriguez-Sibaja,Miguel A Mendez-Piña,Mario I Lumbreras-Marquez,Sandra Acevedo-Gallegos,Berenice Velazquez-Torres,Jose A Ramirez-Calvo
Objective: To compare neonatal outcomes in pregnancies with fetal growth restriction (FGR) by intended delivery mode.Methods: This is a retrospective cohort study of singleton pregnancies with FGR that were delivered ≥34.0 weeks gestation. Neonatal outcomes were compared according to the intended delivery mode, which the attending obstetrician determined. Of note, none of the subjects had a contraindication
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Evaluation of the changes in cardiac morphology of fetuses with congenital heart disease using fetalHQ. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-27 Meixiang Zhang,Yifan Kong,Beilei Huang,Yulin Peng,Cheng Zhou,Junyi Yan,Yingchun Luo
Objective: To evaluate the changes in cardiac morphology of fetuses with congenital heart disease (CHD) using the fetal heart quantitative technique (fetalHQ).Methods: A total of 20 normal pregnant women (control group) and 20 pregnant women suspected of fetal CHD (case group) were included in this study. The dynamic images of the four-chamber view of the fetal heart were recorded and analyzed using
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Cesarean section rate: navigating the gap between WHO recommended range and current obstetrical challenges. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-21 Marco Parasiliti,Annalisa Vidiri,Federica Perelli,Giovanni Scambia,Antonio Lanzone,Anna Franca Cavaliere
The cesarean section (CS) rate is very heterogeneous all over the world, reflecting the differences in the access to healthcare services. In higher-income countries, changes observed in the obstetrical population brought to an increased rate of cesarean section for maternal request. Besides, clinicians are facing an increasing number of induction of labor, with the consequent risk of CS if the management
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Long-term neurodevelopmental effects of exclusively high cord lactate levels in term newborn. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-21 Aslan Yilmaz,Memnune Nur Cebi,Gizem Yilmaz,Gursel Karacaoglu,Sümeyye Nur Aydin,Yildiz Perk,Mehmet Vural
INTRODUCTION Cord arterial blood gas analysis (ABGA) results are used as diagnostic criteria for hypoxic-ischemic encephalopathy in newborns with suspected perinatal asphyxia. This study evaluated the effect of cord ABGA lactate level on the long-term neurodevelopment of newborns without any clinical signs of perinatal asphyxia. METHODS This clinical observation study was designed among term babies
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Effective ventilation and chest compressions during neonatal resuscitation - the role of the respiratory device. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-19 Tanja Restin,Marco Hönes,Helmut D Hummler,Manuel B Bryant
BACKGROUND The success of cardiopulmonary resuscitation (CPR) in newborns largely depends on effective lung ventilation; however, a direct randomized comparison using different available devices has not yet been performed. METHODS Thirty-six professionals were exposed to a realistic newborn CPR scenario. Ventilation with either a bag-valve mask (BVM), T-piece, or ventilator was applied in a randomized
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Small for gestational age at preterm birth identifies adverse neonatal outcomes more reliably than antenatal suspicion of fetal growth restriction. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-19 Maria G Alda,James Holberton,Teresa M MacDonald,Julia K Charlton
BACKGROUND Fetal growth restriction (FGR) is an important reason for premature delivery and a leading cause of perinatal morbidity and mortality. We aimed to evaluate whether classification as small for gestational age (SGA; <10th centile) at birth or antenatal suspicion of FGR was more strongly associated with neonatal morbidity and mortality in preterm infants. METHODS A retrospective audit of infants
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Relationship between air pollutants and spontaneous abortion in a coal resource valley city: a retrospective cohort study. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-15 Jimin Li,Boya Yang,Lang Liu,Jiajia Gu,Meiying Cao,Lili Wu,Jinwei He
OBJECTIVE Pollutants in the atmosphere have been linked to poor pregnancy outcomes in women. However, such investigations are scarce in metropolitan northern China. The major exposure window of air pollution affecting pregnant women is also unknown. METHODS For the analysis, this retrospective cohort study enrolled 6960 pregnant women recorded at Tongchuan People's Hospital from January 2018 to December
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Study on identification of a three-microRNA panel in serum for diagnosing neonatal early onset sepsis. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-15 Yihong Zhao,Chong Lu,Ruqin Zhu,Xiaoyan Hu
BACKGROUND Comparing with other diseases, early onset sepsis (EOS) is a global health concern in neonatal period for its high morbidity and mortality rates. In recent years, many studies have contributed to the figure out the expression patterns of circulating micro-RNAs (miRNAs) in different diseases and progressions, which could function as diagnostic biomarkers for EOS. The purpose of this study
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Mesenchymal stem cell secretome ameliorates over-expression of soluble fms-like tyrosine kinase-1 (sFlt-1) and fetal growth restriction (FGR) in animal SLE model. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-12 Muhammad Adrianes Bachnas,Gustaaf Albert Dekker,Ambar Mudigdo,Bambang Purwanto,Sri Sulistyowati,Erry Gumilar Dachlan,Muhammad Ilham Aldika Akbar,Angliana Chouw,Cynthia Retna Sartika,Widjiati Widjiati
INTRODUCTION In the near future, stem cell research may lead to several major therapeutic innovations in medical practice. Secretome, a "by-product" of stem cell line cultures, has many advantages. Its easiness of storage, usage, and fast direct effect are some of those to consider. Fetal growth restriction (FGR) remains one of the significant challenges in maternal-fetal and neonatal medicine. Placentation
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Predictive value of quantitative fetal fibronectin for spontaneous preterm birth in asymptomatic pregnancies: a systematic literature review and meta-analysis. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-12 Michael S Ruma,Marissa Betts,Sophie Dodman,Binod Neupane
OBJECTIVE Tests capable of accurate prediction of spontaneous preterm birth (sPTB) are crucial to inform clinical decisions to prevent neonatal deaths and reduce the risk of morbidity in surviving infants. A systematic literature review and meta-analysis were performed to assess the utility of the quantitative fetal fibronectin (fFN) test to predict sPTB at different test concentration thresholds.
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Knowledge, attitude and perception of cesarean section among pregnant women attending antenatal clinic at Babcock University Teaching Hospital, Ilishan-Remo, Ogun State. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-12 Bukola Titilope Maitanmi,Oluwasinmibo Victoria Oluyomi,Inioluwa Omowumi Aderemi,Julius Olatade Maitanmi,Abdulmajeed Aminu,Margaret Olutosin Ojewale,Ogechukwu Emmanuel Okondu,Oluwadamilare Akingbade
Background: While the rate of Cesarean Section (CS) has been increasing in developed countries, the same cannot be said about developing countries, especially Nigeria. Despite the various indications of CS that may arise, the CS rate in Nigeria has remained as low as 2.7% as against the 15% acceptable upper limit according to the World Health Organization. The level of knowledge, perception, and attitude
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Associations between maternal stressful life events experiences and risk of neural tube defects in offspring: a systematic review and meta-analysis. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-09 Meng Wang,Xian Chen Jiang,Shi Ming Lai,Zhi Juan Gan,Jin Na Wang,Bing Dong Zhan
OBJECTIVES Multiple factors associated with neural tube defects (NTDs) risk have been identified, yet there is little evidence on the possible effects of maternal stressful life events. In this study, we aimed to investigate the association between stressful life events during the periconceptional period and risk of NTDs in offspring. METHODS Relevant literature was searched in PubMed, Springer Link
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Intrahepatic cholestasis of pregnancy and theory of inheritance of the disease. Literature review. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-09 Weronika Niemyjska-Dmoch,Przemysław Kosiński,Piotr Węgrzyn,Katarzyna Luterek,Aleksandra Jezela-Stanek
Intrahepatic cholestasis during pregnancy is associated with a higher risk of prenatal and maternal complications. There are several new publications and guidelines on the detection and thresholds of intrahepatic cholestasis during pregnancy. However, the genetic background of this disease has rarely been investigated. This is a comprehensive review of the roles of genes in intrahepatic cholestasis
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Predicting poor left ventricular function recovery in Peripartum cardiomyopathy. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-07 Hawani Sasmaya Prameswari,Cindya Perthy Iswandi,Melawati Hasan,Erwan Martanto,Iwan Cahyo Santosa Putra,William Kamarullah,Triwedya Indra Dewi,Mohammad Rizki Akbar
INTRODUCTION Peripartum cardiomyopathy (PPCM) is a rare type of cardiomyopathy that manifests as acute heart failure associated with pregnancy. Delays in early identification result in poor recovery of left ventricular (LV) function; however, no risk prediction model exists. We sought to yield a scoring system known as the Padjadjaran Peripartum CardioMyopathy Recovery (PPCM recovery) score to predict
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Analysis of the application effect of a rapid response team in emergency cesarean section. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-06 Yi Li,Chunfen Yang,Shuangjian Yang,Hui Lan,Dong Yang
INTRODUCTION Emergency cesarean section is one of the most critical methods in the treatment of high-risk emergency obstetric cases. The aim of this study was to explore the clinical effect of constructing a Rapid Response Team (RRT) in emergency cesarean section. METHODS This is a pre- and post-implementation study. The patients who underwent emergency cesarean section were retrospectively analyzed
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Etiology of stillbirth in a tertiary care center: a retrospective cohort study assessing ultrasound, laboratory, and pathology investigations. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-05 Brenden Osborne,Sohini Mitra,Dalia Karol,Pierre Azzi,Kelsie Ou,Kameela M Alibhai,Malia S Q Murphy,Darine El-Chaâr
BACKGROUND Canadian stillbirth data are limited, and a significant proportion of pregnancies resulting in stillbirth have no attributable cause. The objective of this study was to characterize stillbirth case investigations and management at a tertiary care hospital in Ontario, Canada. METHODS This was a retrospective chart review study of all cases of singleton stillbirth at The Ottawa Hospital between
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Risk factors for failure of conversion from epidural labor analgesia to cesarean section anesthesia and general anesthesia incidence: an updated meta-analysis. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-11-05 Pan Li,Xiaoting Ma,Shuang Han,Izumi Kawagoe,Kurt Ruetzler,Amos Lal,Longlu Cao,Ran Duan,Jianli Li
OBJECTIVES Ongoing controversies persist regarding risk factors associated with the failure of transition from epidural labor analgesia to cesarean section anesthesia, including the duration of labor analgesia, gestational age, and body mass index (BMI). This study aims to provide an updated analysis of the incidence of conversion from epidural analgesia to general anesthesia, while evaluating and
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Late third trimester diagnosis of congenital giant hemangioma complicated by the Kasabach-Merritt phenomen: a case report and literature review. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-31 I Fantasia,V Polsinelli,S Ambrosii,S Tabacco,V Stanislao,M Ludovisi,A Dotta,A Conforti,A D'Alfonso,S Di Fabio,M Guido
Objective. To describe the case of a large cervical mass diagnosed in the late third trimester with development of Kasabach-Merritt phenomenon (KMP) in the immediate postnatal period, along with a literature review.Methods. Description of case-report and literature search through Medline/Pubmed, performed from inception to December 2022 for articles relating to the pre and postnatal diagnosis of KMP
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Effects of prepregnancy dietary patterns on infant birth weight: a prospective cohort study. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-30 Yiman Zhang,Yongli Zhao,Yifan Duan,Changqing Liu,Zhenyu Yang,Jingtao Duan,Ze Cui
BACKGROUND Maternal nutrition can have a profound effect on fetal growth, development, and subsequent infant birth weight. However, little is known regarding the influence of prepregnancy dietary patterns. OBJECTIVES This study aimed to explore the effects between prepregnancy dietary patterns on birth weight. METHODS This study included 911 singleton live-born infants from the Taicang and Wuqiang
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Novel approach to prenatal predictors of outcomes for fetuses with severe Ebstein anomaly. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-30 Kavita Narang,Michelle Wyatt,Patrick O'Leary,M Yasir Qureshi,Amy Kolbe,Elizabeth H Stephens,Joseph A Dearani,Rodrigo Ruano
OBJECTIVE Ebstein anomaly (EA) is a cardiac malformation with highly variable presentation and severity with limited perinatal management options. We present incorporation of fetal lung measurements into a multidisciplinary evaluation for counseling and predicting postnatal outcomes in patients with severe EA. METHODS Five fetuses with severe fetal EA were reviewed. Third trimester sonographic observed/expected
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The interaction effect of pre-pregnancy body mass index and maternal age on the risk of pregnancy complications in twin pregnancies after assisted reproductive technology. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-26 Shenglan Chen,Yu Zhou,Qin Mu,Yina Wang
OBJECTIVE The widespread use of assisted reproductive technology (ART) has led to an increased twin pregnancy rate and increased risk of pregnancy complications. Pre-pregnancy body mass index (BMI) and maternal age are both risk factors for pregnancy complications. This study aimed to explore whether there is an interaction effect between pre-pregnancy BMI and maternal age on pregnancy complications
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Omeprazole activates aryl hydrocarbon receptor to reduce hyperoxia-induced oxidative stress in the peripheral blood mononuclear cells from premature infants. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-26 Xi Yang,Zhengrong Bao,Xiaoping Lei,Xia Wang,Shuai Zhao,Fengling Du,Xingling Liu,Wenbin Dong
OBJECTIVE To investigate the correlation between the aryl hydrocarbon receptor (AhR) and reactive oxygen species (ROS) in peripheral blood mononuclear cells (PBMCs) of premature infants, to demonstrate the protective role of AhR against hyperoxia-induced oxidative stress in premature infants and to provide a rational basis for the use of omeprazole (OM) as a new treatment for bronchopulmonary dysplasia
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B-cell-activating factor (BAFF) and platelet-activating factor (PAF) in pregnancies complicated by maternal obesity and diabetes: a preliminary study. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-23 Caterina Neri,Alessandra Ciliberti,Davide Archelao Dessì,Chiara Airoldi,Katia Basello,Andrea Costanzi,Alessandra Familiari,Chiara Tersigni,Mattia Cappelletti,Attilio Francesco Speciani,Antonio Lanzone
OBJECTIVE In pregnancies complicated by maternal obesity and diabetes, a disruption in inflammatory mediators occurs, resulting in endothelial microvascular dysfunction, oxidative stress, tissue damage, and maternal and feto-neonatal complications. To outline this proinflammatory status, an innovative approach is represented by the measurement of proinflammatory cytokines. Among these biomarkers, B-cell-activating
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Evaluation and management of neonatal onset hyperinsulinemic hypoglycemia: a single neonatal center experience. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-20 Handan Bezirganoglu,Nilufer Okur,Kiymet Celik,Funda Feryal Tas,Mehmet Nuri Ozbek
OBJECTIVES To evaluate the clinical characteristics and treatment options of neonates requiring prolonged hospitalization due to persistent hyperinsulinemic hypoglycemia (HH). METHODS This retrospective cohort study included infants >34 weeks of gestation at birth who were born in our hospital between 2018 and 2021, diagnosed with HH, and required diazoxide within the first 28 days of life. The baseline
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Investigation of serum isthmin 1 concentration in pregnant women diagnosed with gestational diabetes mellitus; a case-control study. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-18 Zeynep Şentürk,İbrahim Kale,Murat Muhcu
OBJECTIVE Isthmin 1 (ISM1) is an adipokine that improves hyperglycemia by increasing glucose uptake in a non-insulin-dependent manner. Studies have shown that ISM is associated with the development of type 2 diabetes mellitus. Based on this, we aimed to investigate serum ISM1 concentrations of pregnant women with gestational diabetes mellitus (GDM). METHODS This case-control study was conducted with
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Metabolomics profiling of maternal and umbilical cord blood in normoglycemia macrosomia. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-17 Mianmian Zhu,Rongyue Sun,Lixu Jin,Dandan Yu,Xiaoxia Huang,Ting Zhu,Yujing Gong,Yuan Chen,Jiamin Shi,Qiu Wang,Chaosheng Lu,Dan Wang
Background: Macrosomia is a common disorder that occurs during pregnancy. We investigated the comprehensive metabolite profiles of pregnant maternal and fetal sera in normoglycemic macrosomia in a Chinese population. Methods: Forty pregnant women and their fetuses were included in the study (twenty macrosomia patients and twenty normal-weight controls). Maternal and umbilical cord serum metabolites
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Accuracy of a portable hemoglobinometer (HemoCue) to measure fetal hemoglobin values during in utero transfusion. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-15 Amélie Delabaere,Maeva Guerard,Romain Cahierc,Damien Bouvier,Bruno Pereira,Denis Gallot
OBJECTIVES The current recommended treatment for severe fetal anemia is in utero transfusion (IUT). During this procedure, the evaluation of the necessary volume of transfused blood is based on regular measurement of fetal hemoglobin (FHb) concentration. The gold standard measurement is performed in the biology laboratory. A rapid medical test such as HemoCue® is an effective way to predict FHb concentration
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Value of post-cerclage transvaginal ultrasound in predicting preterm birth at <28 weeks in twin pregnancy with ultrasound-indicated cerclage. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-11 Min Lv,Huanxia Yang,Shuli Zhu,Neng Jin,Chenyu Jiang,Baihui Zhao,Yimin Zhou,Qiong Luo
OBJECTIVE To evaluate the value of transvaginal ultrasound parameters before and after cerclage in twins in predicting spontaneous preterm birth (sPTB) before 28+0 weeks. METHODS We retrospectively studied the medical records of twin-pregnant women who underwent ultrasound-indicated cerclage between January 2016 and February 2022 at our hospital. Recorded transvaginal ultrasound images before and after
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COVID-19 during pregnancy could potentially affect placental function. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-08 Shoichi Magawa,Masafumi Nii,Naosuke Enomoto,Yuya Tamaishi,Sho Takakura,Shintaro Maki,Masaki Ishida,Kazuhiro Osato,Eiji Kondo,Hajime Sakuma,Tomoaki Ikeda
OBJECTIVE COVID-19 is an ongoing pandemic and has been extensively studied. However, the effects of COVID-19 during pregnancy, particularly on placental function, have not been verified. In this study, we used blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI) to evaluate whether COVID-19 incidence during pregnancy has any lasting effects with respect to placental oxygenation. METHODS
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Periostin promotes extensive neovascularization in placenta accreta spectrum disorders via Notch signaling. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-08 Rui Li,Wan Wang,Xia Qiu,Mei He,Xiaoqin Tang,Mei Zhong
OBJECTIVE Extensive neovascularization, closely linked to massive intraoperative blood loss, is a pathological hallmark of placenta accreta spectrum (PAS) cases. This study aims to explore proteins related to neovascularization and elucidate their regulatory roles in PAS, enhancing our understanding of this condition. METHODS The isobaric tags for relative and absolute quantitation technique were used
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Techniques for detecting cervical remodeling as a predictor for spontaneous preterm birth: current evidence and future research avenues in patients with multiple pregnancies. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-10-01 L K Wharton,D O C Anumba
BACKGROUND Spontaneous preterm birth occurs more frequently in multiple pregnancies. This syndrome has multiple triggers that result in a unified downstream pathway of cervical remodeling, uterine activity, and progressive cervical dilatation. Whilst the triggers for labor in multiple pregnancy may be different from singletons, the downstream changes will be the same. Identifying patients at risk of
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Prenatal diagnosis of 15q11.2 microdeletion fetuses in Eastern China: 21 case series and literature review. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-28 Xia-Li Jiang,Bin Liang,Wan-Tong Zhao,Na Lin,Hai-Long Huang,Mei-Ying Cai,Liang-Pu Xu
OBJECTIVE 15q11.2 microdeletion can lead to syndromes affecting the nervous system. However, 15q11.2 microdeletion has large phenotypic differences and incomplete penetrance, which brings challenges to prenatal diagnosis. We reported 21 cases of 15q11.2 microdeletion fetuses in Eastern China and reviewed literature on the prenatal clinical characteristics related to the deletion variants to provide
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Interaction between smoking during pregnancy and gestational diabetes mellitus and the risk of cesarean delivery: evidence from the National Vital Statistics System 2019. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-27 Jie Song,Ruiyu Cai
OBJECTIVE To explore the interaction between smoking during pregnancy (SDP) and gestational diabetes mellitus (GDM) on the risk of cesarean delivery. METHODS This retrospective cohort study utilized data from the National Vital Statistics System (NVSS) 2019. The NVSS database provides data on births and deaths as well as maternal characteristics in the United States. The duration of follow-up was 38
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Group B Streptococcus rectovaginal colonization screening on term pregnancies: culture or polymerase chain reaction? J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-27 Susana Correia Costa,Ana Paula Machado,Cláudia Teixeira,Luísa Cerqueira,Teresa Rodrigues,Manuela Ribeiro,Marina Moucho
OBJECTIVES The aim of this study was to evaluate if screening Group B Streptococcus colonization by intrapartum polymerase chain reaction could improve intrapartum administration of antibiotic prophylaxis, compared with antepartum culture screening and analyze the sensitivity and specificity of polymerase chain reaction test. METHODS 198 pregnant women with Group B Streptococcus colonization antepartum
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Abdominal circumference growth velocity as a predictor of adverse perinatal outcomes in small-for-gestational-age fetuses. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-26 Maria J Rodriguez-Sibaja,Alejandra Villa-Cueva,Maria Ochoa-Padilla,Maria S Rodriguez-Montenegro,Mario I Lumbreras-Marquez,Sandra Acevedo-Gallegos,Juan M Gallardo-Gaona,Yazmin Copado-Mendoza
OBJECTIVE To assess the predictive value of abdominal circumference growth velocity (ACGV) between the second and third trimesters to predict adverse perinatal outcomes in a cohort of small-for-gestational-age fetuses without evidence of placental insufficiency (i.e. fetal growth restriction). MATERIAL AND METHODS This is a single-center retrospective cohort study of all singleton pregnancies with
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Clinical, epidemiological and laboratory characteristics of cases of Covid-19-related maternal near miss and death at referral units in northeastern Brazil: a cohort study. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-25 Anna Catharina M C Cunha,Leila Katz,Arthur Ferreira Cerqueira Amorim,Isabela Cristina Coutinho,Alex Sandro Souza,Sara Katz,Gustavo Souza,Gabriela Souza,Lucas Farias,Raissa Lemos,Maria Zilda Mello,Lucas Neves,Marina Albuquerque,Francisco Edson Feitosa,Jordana Paiva,Carolina Lima,Marcelo Lima,Melania Maria Amorim,
Objective: Covid-19 poses a major risk during pregnancy and postpartum, resulting in an increase in maternal mortality worldwide, including in Brazil; however, little research has been conducted into cases of a near miss. This study aimed to describe the frequency of COVID-19-related near miss and deaths during pregnancy or in the postpartum in referral centers in northeastern Brazil, as well as the
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Postpartum depressive symptoms in women with female genital mutilation in Somalia. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-25 Ozgur Ozer,Esra Keles,Hasan Huseyin Eker,Kurşad Nuri Baydili,Marian Muse Osman
OBJECTIVES This study aimed to identify associated factors for postpartum depression (PPD) among women with female genital mutilation (FGM) in Somalia. METHODS This was a cross-sectional study conducted between February and May 2021 in Somalia Mogadishu-Turkey Recep Tayyip Erdogan Training and Research Hospital, Mogadishu, Somalia. Mothers with any known chronic disease, or psychiatric disorders and
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Perinatal risk factors for neonatal early-onset sepsis: a meta-analysis of observational studies. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-24 Liyan Guo,Wenxiao Han,Yan Su,Na Wang,Xinqing Chen,Jinjin Ma,Jiaojiao Liang,Ling Hao,Changjun Ren
OBJECTIVE Early-onset neonatal sepsis (EONS) remains an important cause of neonatal mortality and has many risk factors, therefore, this study aimed to investigate the perinatal risk factors for EONS. METHODS We searched CNKI, Wan Fang, VIP, CBM, PubMed, Embase, and Web of Science to compile studies regarding the incidence of neonatal early-onset sepsis, published up to 1 May 2022. To evaluate the
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Live birth after single euploid frozen embryo transfer in a 39-year-old woman with high-grade mosaic Turner syndrome. J. Matern.-Fetal Neonat. Med. (IF 1.8) Pub Date : 2023-09-24 Giuliano Bedoschi,Guilherme Gastaldo,Bianca Bianco,Denise Maria Christofolini,Caio Parente Barbosa,Matheus Roque,Paula Andrea Navarro
OBJECTIVE To describe the reproductive and obstetric outcomes of an intracytoplasmic sperm injection cycle with preimplantation genetic testing for aneuploidy in an advanced reproductive-age woman with high-grade mosaic Turner syndrome. METHODS Case report of a 39-year-old woman diagnosed with mosaic Turner Syndrome 45,X[90]/46,XX[10] karyotype who underwent in vitro fertilization treatment with blastocyst