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Effects of vaginal dilation therapy on vaginal length, vaginal stenosis, vaginal elasticity and sexual function of cervical cancer survivors J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-03-11 Yu-Xuan Lin, Fei-Fei Zhao, Wei-Min Kong
Cervical cancer survivors can experience vaginal length shortening, vaginal stenosis, vaginal elasticity deterioration, sexual frequency reduction and sexual dysfunction. This prospective, uncontro...
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Metformin enhances epithelial cell growth inhibition via the protein kinase–insulin-like growth factor binding protein-1 pathway J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-03-11 Xuping Shao, Changling Li, Junhui Liang, Li Changzhong
Abnormal stromal-epithelial cell communication is a pathogenic mechanism in endometriosis, and metformin can modulate it. Insulin-like growth factor binding protein-1 (IGFBP1) plays a role in endom...
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Translation and validation of the Chinese version of the menstrual distress questionnaire J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-03-11 Hsin-Huei Chang, Ya-Chien Hsu, Wen-Ling Liao, Chyi Lo, Cherry Yin-Yi Chang, Chun-Hui Liao, Shan-Yu Su
The Menstrual Distress Questionnaire (MDQ) is a commonly used questionnaire that assesses various symptoms and distress associated with the menstrual cycle in women. However, the questionnaire has ...
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Progestogen only contraception in women with congenital heart disease J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-03-11 Francesc Baró-Mariné, Antonia Pijuan-Domènech, Maria del Mar Goya, Elena Suárez-Edo, Berta Miranda-Barrio, Laura Dos-Subirà, Maria Luisa Pancorbo, Ignacio Ferreira-Gonzalez, Elena Carreras-Moratonas
There is little information of progestogen-only contraceptives in patients with congenital heart disease (CHD) on the long-term.To evaluate the use of contraception in patients with CHD. We studied...
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Red flags for randomisation J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-03-04 Natasha Weaver
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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The effect of the COVID-19 pandemic on the mental health of obstetrics and gynaecology trainees: a world-wide literature review J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-28 G. Ganeshan, H. Sekar, S. Reilly, C. Kuo, S. Singh, J. Michaels, W. Yoong
Coronavirus (COVID-19) pandemic has affected the training and wellbeing of obstetrics and gynaecology (O&G) trainees. The aim of this review is to offer a worldwide overview on its’ impact on the m...
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Causal relationship between affect disorders and endometrial cancer: a Mendelian randomisation study J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-29 Yewu Sun, Shuo Geng, Chunmeng Fu, Xiaoyan Song, Hua Lin, Yidan Xu
The aim was to assess the causal relationship between depression and anxiety disorders and endometrial cancer.We performed two-sample Mendelian randomisation analysis using summary statistics from ...
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Construction of a ferroptosis and hypoxia-related gene signature in cervical cancer to assess tumour immune microenvironment and predict prognosis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-29 Haiyan Wu, Yayun Fan, Yuanyuan Bao, Qing Zhou, Lei Xu, Yao Xu
This study aimed to investigate the potential role of ferroptosis/hypoxia-related genes in cervical cancer to improve early management and treatment of cervical cancer.All data were downloaded from...
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Impact of haemostasis methods during ovarian cystectomy on ovarian reserve: a pairwise and network meta-analysis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-26 Qin Xie, Yue Xie, Ying Shi, Xiaozhen Quan, Xuezhou Yang
Haemostasis during ovarian cystectomy is reported to damage the ovarian reserve, but the comparative impacts of three haemostasis methods (bipolar energy, suture and haemostatic sealant) on ovarian...
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Do maternal haemodynamics have a causal influence on treatment for gestational diabetes? J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-22 Abigail R. Anness, Michael Foster, Mohammed W. Osman, David Webb, Thompson Robinson, Asma Khalil, Neil Walkinshaw, Hatem A. Mousa
Arterial stiffening is believed to contribute to the worsening of insulin resistance, and factors which are associated with needing pharmacological treatment of gestational diabetes (GDM), such as ...
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Factors that influence the choice of long-acting reversible contraceptive use among adolescents post-abortion in Chongqing, China: a cross-sectional study J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-14 Fengzhen Jin, Yuanpei Yang, Junjie Sun, Ruiyue Li, Fei Yao, Xiaoli Liu
Induced abortion can seriously harm the physical and mental health of adolescent women. Long-acting reversible contraception (LARC) can effectively reduce unplanned pregnancies and prevent repeated...
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Transvaginal ultrasound and magnetic resonance imaging in the diagnosis of endometrioma: a systematic review and meta-analysis of diagnostic test accuracy studies J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-13 Fleur Serge Kanti, Rose Gorak Savard, Frédéric Bergeron, Hervé Tchala Vignon Zomahoun, Antoine Netter, Sarah Maheux-Lacroix
The diagnosis of endometriomas in patients with endometriosis is of primary importance because it influences the management and prognosis of infertility and pain. Imaging techniques are evolving co...
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Human papillomavirus type 16 E7 promotes cell viability and migration in cervical cancer by regulating the miR-23a/HOXC8 axis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-13 Yahang Chen, Lei Sun, Lin Li
Human papillomavirus (HPV) is a risk factor for the occurrence of cervical cancer (CC). Here, we aimed to explore the role of HPV16 in CC and identify the underlying mechanism.The expression of miR...
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Statement of retraction: Clomiphene citrate or aromatase inhibitors combined with gonadotropins for superovulation in women undergoing intrauterine insemination: a prospective randomised trial J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-08
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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Statement of retraction: Subfertility treatment in women with systemic lupus erythematosus J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-07
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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Vaginal bleeding in pregnancy and adverse clinical outcomes: a systematic review and meta-analysis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-02-02 Arezoo Karimi, Kourosh Sayehmiri, Mojtaba Vaismoradi, Mostafa Dianatinasab, Salman Daliri
Background: Vaginal bleeding during pregnancy has been recognised as a significant risk factor for adverse pregnancy outcomes. This study aimed to investigate the association between vaginal bleedi...
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GLP1R boosts survival, migration and invasion of endometrial cancer cells and protects against ferroptotic cell death J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-25 Wu Li, Wen Lyu, Songjun Liu, Fan Ruan, Xinmei Zhang
Despite the strong evidence concerning carcinogenic roles of glucagon-like peptide 1 receptor (GLP1R), the role of this gene in endometrial cancer (EC) remains elusive. This study investigated the ...
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Comparison of embryo quality and pregnancy outcomes for patients with low ovarian reserve in natural cycles and mildly stimulated cycles: a cohort study J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-23 Rui-Ying Yuan, Sen Li, Xie Feng, Xiao-Long Li, Xiao-ting Lin, Fu-min Gao, Hai-Jing Zhu, Yong-shi Li, Yan-chu Li, Xiang-Hong Ou
As women with low ovarian reserve embark on the challenging journey of in-vitro fertilisation (IVF) treatment, the choice between natural and mildly stimulated cycles becomes a pivotal consideratio...
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Minimally invasive surgical treatment of Robert’s uterus with missed miscarriage: case report J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-21 Houyu Yang, Yuanjunzi Shi, Gang Ji
Robert’s uterus was firstly reported in 1970, it’s a rare Müllerian duct anomaly with 2 intra-uterine cavities divided by asymmetrical septum. One of the cavities is completely obstructed to cervix...
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A noninvasive method for the detection of foetal DNA in early pregnancy based on differential methylation pattern of Ras association domain family member 1A J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-10 Yulin Sha, Wei Liu, Jiongzhi Hong, Yan Yang, Jian Yu, Xiaodong Fu
The detection of foetal DNA and extravillus trophoblasts (EVTs) in early pregnancy in cervical and uterine samples offers a potential pathway for non-invasive prenatal diagnostics. However, the cha...
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Abnormal preoperative haematological parameters in Endometrial cancer; reflecting tumour aggressiveness or reduced response to radiotherapy? J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-07 Stephanie W. Vrede, Hannah Donkers, Casper Reijnen, Anke Smits, Nicole C.M. Visser, Peggy M. Geomini, Huy Ngo, Dennis van Hamont, Brenda M. Pijlman, Maria Caroline Vos, Marc P.L.M. Snijders, Roy Kruitwagen, Ruud L.M. Bekkers, Khadra Galaal, Johanna M.A. Pijnenborg
In endometrial cancer (EC), preoperative anaemia, thrombocytosis and leucocytosis appear to be associated with worse prognosis. It remains unclear whether these parameters solely reflect tumour agg...
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Prenatal MRI for the diagnosis of foetal pial arteriovenous fistula: a case report and literature review J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2024-01-04 Yimin Cao, Weixin Meng, JianXiong Zheng, Chengye Zhang, Duo Gao, LiXia Zhou
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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Successful management of pyoderma gangrenosum after caesarean section: a case report J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-27 Liqin Yang, Yiping You, Zheng Li, Yingxue Song, Xiaozhou Jia
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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Prevalence of prescribing topical corticosteroids to patients with lichen sclerosus following surgery for vulvar cancer: a survey among gynaecologic oncologists in The Netherlands J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-29 Féline O. Voss, Karelina L. Groenewegen, Hester Vermaat, Maaike C.G. Bleeker, Marc van Beurden
Vulvar lichen sclerosus (LS) is a chronic inflammatory dermatosis which can progress to precursor lesion differentiated vulvar intraepithelial neoplasia (dVIN) and vulvar squamous cell carcinoma (V...
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How I maximised my training during the COVID-19 pandemic J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-26 H. Sekar, L. Berg, V. Sampson, W. Yoong
The COVID-19 pandemic was declared in March 2020 and London maternity units were among the first in the United Kingdom to report maternal infection and vertical transmission. To manage resources, o...
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The oncological and reproductive outcomes of fertility-preserving treatments for stage 1 grade 1 endometrial carcinoma: a systematic review and meta-analysis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-21 M. Olabisi Ogunbiyi, Samuel Oxley, Radha Graham, Adeola Olaitan
The number of patients desiring fertility-preserving treatment for endometrial cancer rather than standard surgical management continues to increase.We aimed to evaluate the efficacies of fertility...
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Statement of retraction: a prospective randomised trial comparing Foley catheter, oxytocin, and combination Foley catheter-oxytocin for labour induction with unfavourable cervix J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-18
Published in Journal of Obstetrics and Gynaecology (Vol. 44, No. 1, 2024)
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Modifiable prognostic factors in uterine fibroid development: a systematic review of literature J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-16 Alieke L. Keizer, Annika Semmler, Helen S. Kok, Paul J.M van Kesteren, Judith A.F Huirne, Wouter J.K Hehenkamp
Many risk factors in uterine fibroid development have been identified, but women and their physicians are less aware of the influence of lifestyle on uterine fibroid development. The objective of t...
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Epigenetic phenotype of plasma cell-free DNA in the prediction of early-onset preeclampsia. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-12-01 Wei He,Yi Zhang,Kai Wu,Yunan Wang,Xin Zhao,Lijuan Lv,Congmian Ren,Jiaqi Lu,Jiexia Yang,Aihua Yin,Guocheng Liu
BACKGROUND In the current study, we sought to characterise the methylation haplotypes and nucleosome positioning patterns of placental DNA and plasma cell-free DNA of pregnant women with early-onset preeclampsia using whole genome bisulphite sequencing (WGBS) and methylation capture bisulphite sequencing (MCBS) and further develop and examine the diagnostic performance of a generalised linear model
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Role of the CD40-CD40L expression level pathway in the diagnosis of unexplained recurrent pregnancy loss. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-30 Hui Ding,Guoqian An
BACKGROUND Unexplained recurrent spontaneous pregnancy loss (URPL) lacks effective treatment and reliable early diagnosis and prediction. Immunologic dysfunction can be an underlying cause of recurrent pregnancy loss (RPL). Considering the regulatory role of CD40-CD40L in immune responses, we explored its clinical significance in URPL. METHODS The 108 women with URPL who were treated in Hebei Yanda
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Factors associated with gestational weight gain in women with morbid obesity. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-28 Frankie J Fair,Hora Soltani
BACKGROUND Women with obesity are at increased risk of excessive gestational weight gain. Women with a body mass index (BMI) of 40 kg/m2 or more are known to have different patterns of weight gain than women with lower levels of obesity. This study therefore aimed to determine the characteristics associated with gestational weight gain (GWG) among women with a BMI of 40 kg/m2 or more. METHODS Secondary
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Is platelet to lymphocyte ratio predictive of preeclampsia? A systematic review and meta-analysis. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-28 Tianyong Qiang,Xiuqin Ding,Jiajia Ling,Meirong Fei
BACKGROUND To evaluate the value of the platelet-to-lymphocyte ratio (PLR) in predicting preeclampsia (PE) in pregnant women. METHODS PubMed, EMBASE and Web of Science databases were searched for observational studies (cohort, case-control or cross-sectional) that reported pre-treatment maternal PLR values in women with and without PE. The analysis was done using a random effects model. Pooled effect
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Diminished ovarian reserve is associated with metabolic disturbances and hyperhomocysteinemia in women with infertility. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-27 Yuehong Lu,Zhoulan Xia
BACKGROUND To distinguish the metabolic profile between women with diminished ovarian reserve (DOR) and those with normal ovarian reserve (NOR). METHODS In this retrospective study, we enrolled 524 women under the age of 40 who were experiencing infertility: 261 in the DOR group and 263 in the NOR group. Physical characteristics and metabolic parameters were compared between these two groups. RESULTS
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Association between nutrient intake and female infertility: a study based on NHANES database. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-27 Xiaowei Ji,Yao Ye,Lin Wang,Suying Liu,Xi Dong
BACKGROUND This study was designed to investigate the association between nutrients and female infertility. METHODS A cross-sectional study on 18-45 years of age reproductive-age women was conducted using the data from the National Health and Nutrition Examination Surveys (NHANES) for the periods 2013-2014 and 2015-2016. Multivariate logistic regression analysis was performed to evaluate the association
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A retrospective study of Pipelle endometrial biopsy for ovarian, fallopian tube, and peritoneal cancers. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-20 Ryo Tamura,Yohei Kitani,Kotaro Takahashi,Masayuki Yamaguchi,Nobumichi Nishikawa,Takashi Kawasaki,Akira Kikuchi
OBJECTIVES Although the Pipelle endometrial biopsy is widely performed as a practical and minimally invasive test for endometrial disease(s), its effectiveness in ovarian cancer has not been explored. The aim of the present study was to evaluate the results of Pipelle endometrial biopsy for ovarian, fallopian tube, and peritoneal cancers. METHODS A pre-treatment Pipelle-endometrial biopsy was performed
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Effects of sirtuin 1 deficiency on trophoblasts and its implications in the pathogenesis of pre-eclampsia. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-15 Hongbiao Yu,Ling Chen,Ping Du,Xianping Liu,Ying Xia
BACKGROUND Sirtuin 1 (SIRT1) is mainly localised in syncytiotrophoblasts and cytotrophoblasts, and is involved in pregnancy regulation. However, data on the association between SIRT1 and pre-eclampsia (PE) remains limited. This study aimed to investigate the role of SIRT1 in PE pathophysiology. METHODS Placental SIRT1 expression, as well as serum SIRT1, placental growth factor (PlGF), and soluble FMS-like
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Tanshinol inhibits trophoblast cell migration and invasion by regulating Gadd45a in preeclampsia. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-08 Yanlin Yang,Haixia Shang,Jingfen Sun,Xiaofeng Shi,Bohui Zhou
OBJECTIVE Tanshinol is an active constituent of Salvia miltiorrhiza that possesses anti-inflammatory, antioxidant, and antibacterial activities. Therefore, this study attempted to detect whether it has a role in the treatment of preeclampsia (PE). METHODS In this study, we explored the effect of tanshinol on the development of PE at the cellular level. The effect of tanshinol on cell proliferation
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Identification of a prognostic model based on immune and hypoxia-related gene expressions in cervical cancer. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-08 Liqun Wang,Caizhi Wang,Yu He,Maosheng Jin,Lu Lin,Xuejuan Jiao,Xiaowen Hu,Yafei Wang
BACKGROUND Tumour immune microenvironment (TIME) has long been a key direction of tumour research. Understanding the occurrence, metastasis and other processes of cervical cancer (CC) is of great significance in the diagnosis and prognosis of tumours. METHODS Here, this study applied the univariate Cox regression model to determine the prognostic association of immune and hypoxia signature genes in
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Blood manganese level and gestational diabetes mellitus: a systematic review and meta-analysis. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-11-03 Yingmei Sun,Yu Zhang
BACKGROUND Previous studies evaluating the relationship between blood manganese (Mn) level and gestational diabetes mellitus (GDM) in pregnant women showed inconsistent results. A systematic review and meta-analysis was therefore performed to investigate the above association. METHODS Relevant observational studies were obtained by search of electronic databases including Medline, Embase, Cochrane
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Live birth rate following endometrial preparation with daily versus depot GnRH agonist. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-10-30 Ulas Fidan,Mustafa Ozturk,Temel Ceyhan,Lala Kazımova,Emre Karasahin
BACKGROUND Gonadotrophin-releasing hormone agonist (GnRHa) downregulates gonadotropin secretion in the pituitary gland. It is used both in ovulation induction protocols and in artificial endometrium preparation. Frozen-thawed embryo transfer to artificially prepared endometrium (FET-APE) is a frequent procedure in vitro fertilization (IVF) which requires GnRHa. It can be used either as a daily low-dose
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Caesarean sections before and during the COVID-19 pandemic in western Sydney, Australia. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-10-26 Lieu Thi Thuy Trinh,Helen M Achat,Andrew Pesce
BACKGROUND To determine the changes in emergency and elective caesarean section (CS) rates since the COVID-19 pandemic, identify the groups most affected, and examine changes in the factors associated with CS rates, and reasons for CS. METHODS We conducted a retrospective cohort study using routinely collected data of 22,346 births from before the pandemic (January 2018-February 2020) and 18,597 births
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Risk factors associated with periodontal disease and its impact on quality of life among pregnant women. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-10-13 Hsiang-Hsi Hong,Yi-Heng Chen,Po-Jen Cheng,Min-Yu Chang,Li-Lan Chuang
BACKGROUND Periodontal disease during pregnancy affects maternal oral health and increases the risk of adverse pregnancy outcomes. However, studies on the risk factors for periodontal disease and its impact on oral health-related quality of life in pregnant women in Taiwan are lacking. This present study aimed to identify the risk factors associated with periodontal disease during pregnancy and examine
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Survival of women with cervical cancer in East Africa: a systematic review and meta-analysis. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-09-30 Roza Kassa,Yang Irene,Edom Woldetsadik,Eshetu Kidane,Melinda Higgins,Tariku Dejene,Jessica Wells
BACKGROUND The prognosis for cervical cancer varies greatly between nations. The disparity in cancer survival rates within nations is largely a result of disparities in public knowledge, the accessibility of cancer services, diagnosis and treatment. The purpose of this systematic review and meta-analysis is to assess the survival rate and associated factors among cervical cancer patients in East Africa
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Serum protein profile analysis via label-free quantitation proteomics in patients with early-onset preeclampsia. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-09-24 Qinghong Ji,Shulin Zhang,Wen Jiang,Jue Wang,Yun Luan,Qian Xin
BACKGROUND Preeclampsia (PE) is a serious pregnancy complication, resulting in potentially life-threatening conditions for both mother and foetus. It is worth noting that early-onset PE has become a great challenge for clinicians due to its complex manifestation, rapid progression and serious complications. This study aims to investigate differential serum proteome profiles in patients with early-onset
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Is separating obstetrics from gynaecology the way forward? A UK perspective. J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-09-21 Marwan Habiba
A recent editorial in this Journal argued that increasing surgical complexity coupled with more limited training calls for separating obstetrics from gynaecology. The speciality suffers manpower challenges and high attrition rates. There is an apparent gulf in approach between researchers focussing on the views of UK graduates or trainees and workforce planners who address the problem through overseas
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Maternal gestational weight gain and adverse pregnancy outcomes in non-diabetic women J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-09-06 Binbin Yin, Lingwei Hu, Kaiqi Wu, Yanni Sun, Xingjun Meng, Wanlu Zheng, Bo Zhu
Abstract Objective This study investigated the relationship between maternal gestational weight gain (GWG) and the risk of adverse pregnancy outcomes in gestational diabetes mellitus (GDM)-negative pregnant women. Methods We did a retrospective cohort study between 1 July 2017, and 1 January 2020, at Women’s Hospital, Zhejiang University School of Medicine. Firstly, pregnant women were divided into
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KLF2 transcription suppresses endometrial cancer cell proliferation, invasion, and migration through the inhibition of NPM1 J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-23 Xiyun Cheng, Changmei Shen, Zhenrong Liao
Abstract Endometrial cancer (EC) is the most common gynaecologic malignancy. This study was to explore the role of kruppel-like factor 2 (KLF2) in EC cell behaviours. The expression of KLF2 in EC and its correlation with NPM1 were first predicted on the database. Levels of KLF2 and nucleophosmin 1 (NPM1) in EC cell lines were then determined. After transfection of the overexpression vector of KLF2
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Effectiveness of mobile health interventions for pregnant women with gestational diabetes mellitus: a systematic review and meta-analysis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-22 Hui Xin Wei, Yi Ling Yang, Ting Yu Luo, Wei Qiang Chen
Abstract Gestational diabetes mellitus is a growing global health problem. Inadequate management during pregnancy can lead to maternal and foetal complications. Currently, mobile health (mHealth) delivers healthcare services, playing an increasingly important role in the management of blood glucose in GDM. This study aimed to systematically evaluate the effectiveness of mHealth intervention in pregnant
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CircEpha5 regulates the synthesis and secretion of androgen in mouse preantral follicles by targeting miR-758-5p J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-09 Xueying Zhang, Jiaxuan Liu, Hao Wu, Yan Chen, Xuesen Zhang, Boqun Xu
Abstract Circular RNAs are involved in the pathogenesis of various diseases, although its expression pattern and role in polycystic ovary syndrome (PCOS), characterised by hyperandrogenism, are not very clear. This article assessed the circRNAs expression profile in the ovaries of PCOS mice by circRNAs high-throughput sequencing and explored the role of circEpha5 in hyperandrogenism. The results showed
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Swedish obstetric thromboprophylaxis guideline: background and update J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-08 Pelle G. Lindqvist, Eli Westerlund, Margareta Hellgren
Abstract Risk estimation concerning venous thromboembolism (VTE) and thromboprophylaxis for those at risk is routine in pregnancy. For 20 years, Swedish obstetricians have followed a weighted-risk algorithm guideline for risk estimation, based on which patient selection, timing, duration and dosage of thromboprophylaxis are determined. This article presents the latest update, the basis for the algorithm
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Editorial J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-07 Ciara Shiel, Wai Yoong
Published in Journal of Obstetrics and Gynaecology (Vol. 43, No. 2, 2023)
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Relationship between maternal ABO blood groups and pregnancy outcomes: a retrospective cohort study in Dongguan, China J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-04 Jing-Yun Yu, Bi Jiang, Xin-Jian Zhang, Si-Si Wei, Wei-Chao He
Abstract The purpose of this study was to study the relationship between maternal ABO blood groups and pregnancy outcomes. A total of 29,658 couples in Dongguan were selected as the research subjects. We obtained data on ABO blood groups and pregnancy outcomes and explored the relationship between them through log binomial regression and survival analysis. Compared to mothers with type B blood, the
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Recurrent miscarriage and infertility: a national service evaluation J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-08-02 Laura Linehan, Marita Hennessy, Keelin O’Donoghue
Abstract The appropriate clinical care of women/couples with infertility experiencing recurrent miscarriage (RM) is overlooked in international guidelines. We sought to evaluate care provision for women/couples with RM and infertility across public (19 clinics providing RM care, five fertility clinics) and private sectors (nine fertility clinics) using adapted guideline-based key performance indicators
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Radiotherapy for postoperative vaginal recurrences of cervical squamous cell carcinoma: analysis of dosing and prognosis J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-07-18 Ziye Zheng, Ke Hu, Xiaorong Hou, Lihua Yu, Junfang Yan, Fuquan Zhang
Abstract Squamous cell carcinoma (SCC) is the most common type of vaginal recurrence in cervical cancer patients, and the role of salvage radiotherapy on these patients remains unclear. This study aimed to investigate the efficacy of salvage radiotherapy for vaginal recurrence of SCC in patients who previously underwent surgery and to explore prognostic factors associated with survival. Ninety-seven
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Statement of retraction: a new technique for uterine incision closure at the time of caesarean section: does it make a difference? J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-07-18
Published in Journal of Obstetrics and Gynaecology (Vol. 43, No. 2, 2023)
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Umbilical artery ultrasound haemodynamics combined with serum adiponectin levels can aid in predicting adverse pregnancy outcomes in patients with severe pre-eclampsia J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-07-18 Zhi Zhang, Fei Liu, Qiling Zhang, Danya Li, Liping Cai
Abstract Severe pre-eclampsia is a leading cause of maternal and perinatal morbidity and mortality. This retrospective study explored pregnancy outcome predictive values of umbilical artery Doppler with serum adiponectin in severe pre-eclampsia. Fasting elbow venous blood was collected from 118 severe pre-eclampsia patients [maternal systolic pressure ≥ 160 mmHg and/or diastolic pressure ≥ 110 mmHg + minimal
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Circular RNA differential expression profiles and bioinformatics analysis of hsa_circRNA_079422 in human endometrial carcinoma J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-07-05 Yuwei Li, Ziling Yang, Mengyao Zeng, Ying Wang, Xin Chen, Shibo Li, Xiaotong Zhao, Yuhui Sun
Abstract The aim of our study was to explore circular RNA (circRNA) expression profiles associated with human endometrial carcinoma (EC) and to analyse the molecular mechanisms involved in cancer development and their potential clinical importance. Differential expression profiles were revealed by Arraystar human circRNA microarray analysis. The results of the circRNA microarray were confirmed by quantitative
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Obstetrics and gynaecology: one specialty or two? J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-07-04 Ayman A. A. Ewies
Published in Journal of Obstetrics and Gynaecology (Vol. 43, No. 2, 2023)
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Statement of retraction: Effects of dexamethasone on foetal Doppler flow velocimetry J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-06-28
Published in Journal of Obstetrics and Gynaecology (Vol. 43, No. 2, 2023)
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Bioinformatics analysis of the clinicopathological and prognostic significance of BAG3 mRNA in gynecological cancers J. Obstet. Gynaecol. (IF 1.3) Pub Date : 2023-06-28 Zi-mo Wang, Li Zhang, Dong-hui Ren, Cong-yu Zhang, Hua-chuan Zheng
Abstract BAG3 is a co-chaperone BAG family protein that plays important roles in protein homeostasis, cell survival, cell motility, and tumour metastasis. This study aimed to clarify the clinicopathological and prognostic implications of BAG3 mRNA expression in tumours. We performed bioinformatics analysis on BAG3 mRNA expression using TCGA, XIANTAO, UALCAN, and Kaplan-Meier plotter databases. BAG3