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Which left atrial volume measurement should we use in the neonatal intensive care? Early Hum. Dev. (IF 2.5) Pub Date : 2024-03-10 Enrico Petoello, Emma Kerkow, Nilkant Phad, Benjamim Ficial, Koert de Waal
Increased left atrial volume (LAV) is a marker of cardiovascular risk. Echocardiography standards to assess LAV in adults and children are the biplane area-length method (AL) and method of disks (MOD). LAV in neonatology is usually derived as M-mode ratio between the LA and the Aorta (LAAo). The aim of this study is to determine feasibility and reliability of these methods in neonatal clinical practice
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Prolonged renal function impairment in infants born during the peri-viable period: A retrospective longitudinal cohort study Early Hum. Dev. (IF 2.5) Pub Date : 2024-03-06 Kyosuke Ibi, Naoto Takahashi
The number of infants born during the peri-viable period who survive has been increasing. To clarify renal function in infants from the time of birth during the peri-viable period until their due date. This retrospective cohort study was conducted at a single center. We reviewed the data of infants born at ≤28 weeks of gestation between 2018 and 2022 at our hospital. The infants were divided into the
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Analysis of perinatal risk factors for massive pulmonary hemorrhage in very low birth weight infant: A nationwide large cohort database Early Hum. Dev. (IF 2.5) Pub Date : 2024-03-05 Jong Ki Jung, Eun Yeob Kim, Ju Sun Heo, Kyu Hee Park, Byung Min Choi
To determine perinatal risk factors for Massive pulmonary hemorrhage (MPH) and MPH-caused mortality to guide clinicians in implementing preventive measures at the beginning of life for improving the survival of very low birth weight infant (VLBWIs). A total of 13,826 VLBWIs born between 2013 and 2020 in the Korean Neonatal Network database were included. MPH occurred in 870 (6.3 %) VLBWIs. Among infants
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Active versus restrictive ligation strategy for patent ductus arteriosus – A retrospective two-center study of extremely preterm infants born between 22 + 0 and 25 + 6 weeks of gestational age Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-29 Fanny Söderström, Richard Sindelar, Karl Wilhelm Olsson, Sawin Yousef, Daniela Todorova, Joanna Pestalozzi, Mats Mellander, Renske Raaijmakers
Patent ductus arteriosus (PDA) in premature infants is associated with adverse clinical outcomes. Mode and timing of treatment are still controversial. Data are limited in the most extremely premature infants <26 weeks of gestational age (GA), where clinical problems are most significant and patients are most vulnerable. To investigate whether different approaches to surgical closure of PDA in two
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Relationships between preterm medical factors and feeding behaviors at term-equivalent age Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-28 Carolyn Ibrahim, Molly Grabill, Joan Smith, Roberta Pineda
To identify relationships between early medical factors and preterm infant feeding behaviors at term-equivalent age. Forty-three very preterm infants born ≤32 weeks gestation had standardized feeding assessments using the Neonatal Eating Outcome Assessment at term-equivalent age (36–42 weeks postmenstrual age). Medical factors were collected and analyses were run to determine if associations between
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Impact of low birth weight on academic attainment during adolescence: A comprehensive retrospective cohort study using linked data Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-27 Getinet Ayano, Berihun Assefa Dachew, Rosanna Rooney, Christina M Pollard, Rosa Alati
This study addresses a critical knowledge gap by exploring the intricate relationship between low birth weight (LBW) and the heightened risk of suboptimal academic achievement during adolescence through a comprehensive retrospective cohort design. In this registry-based cohort study, meticulously linked health and curriculum-based test data for individuals born in New South Wales (NSW), Australia,
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Association between the digit ratio (2D:4D), handgrip strength, wrist ratio, and body fat distribution in women with different carpal tunnel syndrome severity Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-15 İrfan Akyıldız, Gülay Açar, Aynur Emine Çiçekcibaşı, Muzaffer Mutluer
To evaluate the relationship of the second to fourth digit ratio (2D:4D), a biomarker of prenatal sex hormone exposure, with wrist ratio (WR), wrist-palm ratio (WPR), body mass index (BMI), waist-hip ratio (WHR), and handgrip strength (HGS) in different carpal tunnel syndrome (CTS) severity. This study involved 90 female participants (aged 18 to 83) with CTS. According to CTS severity, the participants
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Similar early intervention referral rates following in-person administration of the Bayley Scales of Infant and Toddler Development, 4th Edition versus Telehealth Administration of the Developmental Assessment in Young Children, 2nd Edition in the high-risk infant population Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-14 Jasmine C. Ke, Panteha Hayati Rezvan, Douglas Vanderbilt, Christine B. Mirzaian, Alexis Deavenport-Saman, Beth A. Smith
Infants with prematurity, low birthweight, and medical comorbidities are at high risk for developmental delays and neurodevelopmental disabilities and require close monitoring. Due to the COVID-19 pandemic, high-risk infant follow-up (HRIF) programs have adapted to perform developmental assessments via telehealth. Describe the referral rates to initiate, continue, or increase/add early intervention
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Agreement between Hammersmith Neonatal Neurological Examination (HNNE) and Test of Infant Motor Performance (TIMP) in neurodevelopmental assessment of preterm infants <32 weeks' gestation at term corrected age Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-14 Mandi Suet Ning See, Imelda Lustestica Ereno, Wan Ying Teh, Vijayendra Ranjan Baral, Roger Daniel Vaughan, Cheo Lian Yeo
To determine the agreement between HNNE and TIMP at TCA for preterm infants born <32 weeks' gestation, and to evaluate their correlation to PDMS-2 at 12-month corrected age (CA). Infants born between November 2013 to June 2022 who had both HNNE and TIMP performed at TCA of 37–41 weeks gestation, and motor outcome assessed using the PDMS-2 at 12-month old were enrolled. The HNNE and 12-month PDMS-2
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Investigating behaviour from early- to mid-childhood and its association with academic outcomes in a cohort of children born at risk of neonatal hypoglycaemia Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-09 Jozie Sharpe, Luling Lin, Zeke Wang, Nike Franke
High rates of academic underachievement at 9–10 years have been identified in children born at risk of neonatal hypoglycaemia. This study investigated the stability of behaviour from early to mid-childhood and how this relates to academic outcomes in children born with at least one risk factor of neonatal hypoglycaemia in Aotearoa, New Zealand. Behaviour data was collected using the Bayley Scales of
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Neurodevelopmental outcome at 6 months of age of full-term neonates with hyperbilirubinemia necessitating exchange transfusion Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-08 Esraa Ahmed Elmazzahy, Zahraa Ezz El Din, Marina Atef Nessem, Sarah El Tatawy
Bilirubin neurotoxicity involves a spectrum of varying severity that could result in adverse long-term sequelae. To compare the neurodevelopmental outcome of full-term neonates who underwent exchange transfusion with those who did not. A retrospective cohort study. This study included a retrospective review of records of sixty neonates who were matched in admission ages and serum bilirubin levels and
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Effects of skin-to-skin contact in supported diagonal flexion positioning on movement quality in very preterm infants at term age Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-06 Aude Buil, Nelly Thomas, Benoît Chevalier, Emmanuel Devouche
Preterm birth is associated with a high risk of long-term neuromotor disabilities such as coordination of movements, deficient antigravity limb movement, less adaptive postural control strategies, head deformities… The aim of the present study was to examine the potential positive impact of a Supported Diagonal Flexion (SDF) skin-to-skin contact (SSC) positioning on the neuromotor development and movement
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Maternal and neonatal outcomes for kidney transplant recipients Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-06 Jianglin Ma, Fang Luo, Lingling Yan
To report pregnancy outcomes for women with kidney transplantation and investigate whether different intervals after transplantation have different effects on pregnancy outcomes. A single-center retrospective study was performed. Based on intervals after transplantation, pregnant women with kidney transplantation are divided into two groups: intervals <5 years and ≧5 years. The maternal and neonatal
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360-degree phenomenology: A qualitative approach to exploring the infant experience of hospitalisation in neonatal intensive care Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-04 Natalie Duffy, Leah Hickey, Karli Treyvaud, Clare Delany
This paper describes the development and justification of a qualitative methodology aimed at exploring the infant's personal experience of hospitalisation in the neonatal intensive care unit (NICU). We begin by briefly reviewing existing methods for documenting and recording infant experiences. These methods focus on the clinical needs of the infant predominantly through quantifiable medical outcome
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A comparative analysis of oropharyngeal functions in preterm and term children with cerebral palsy Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-02 Seda Nur Kemer, Selen Serel-Arslan
This study aims to compare term and preterm children with Cerebral Palsy (CP) in terms of their oropharyngeal functions. A total of 50 children with CP participated in the study, and were divided into two groups according to their birth history including preterm group (gestational age below 37 weeks; 60 % female; mean age = 6.86 ± 4.35 years) and term group (gestational age between 37 and 41 weeks;
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Response to the Letter to the Editor by Dr. Keith Barrington Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-02 Mohammad Chehrazi, Sabita Uthaya, Neena Modi
Abstract not available
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Early childhood development monitoring during the first thousand days: Investigating the relationship between the developmental surveillance instrument and standardized scales Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-02 Kedma Teixeira Montedori, Maria Cecília Marconi Pinheiro Lima
This study aims to investigate the relationship between the Developmental Surveillance Instrument – (IVD), found in the Child's Booklet (CC), and standardized scales: Alberta Infant Motor Scale (AIMS) and Denver Developmental Screening Test (Denver-II). Employing an exploratory observational approach, we adopted a prospective longitudinal design with a quantitative approach. The convenience sample
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Role of patent ductus arteriosus in preterms in long-term outcome Early Hum. Dev. (IF 2.5) Pub Date : 2024-02-01 Moniek S. Veldhuis, Laura M.L. Dix, Johannes M.P.J. Breur, Willem B. de Vries, Corine Koopman, Maria J.C. Eijsermans, Henriette F.N. Swanenburg de Veye, Mirella C. Molenschot, Petra M.A. Lemmers, Frank van Bel, Daniel C. Vijlbrief
This study aimed to determine long-term neurodevelopmental outcome and cerebral oxygenation in extremely preterm infants, comparing those with a hemodynamic significant patent ductus arteriosus (hsPDA) to those without. We included infants born before 28 weeks of gestation from 2008 to 2010 with routine echocardiography. Prior to echocardiography, regional cerebral oxygen saturation was measured. At
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Antenatal corticosteroid administration is associated with lower risk of severe ROP in preterm twin infants Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-30 Omer Ertekin, Buse Ozer Bekmez, Mehmet Buyuktiryaki, Mustafa Senol Akin, Evrim Alyamac Dizdar, Fatma Nur Sari
Robust evidence revealed the impact of antenatal corticosteroid (ACS) administration on lower mortality and short-term neonatal outcomes in singleton preterm infants. We aimed to investigate the impact of ACS therapy on morbidity and mortality in preterm twin infants. We conducted this retrospective single-center study from to the records of twin babies of 24–30 weeks of gestation admitted to the neonatal
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Early metabolic markers as predictors of respiratory complications in preterm infants with bronchopulmonary dysplasia Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-28 You You, Liping Wang, Chengbo Liu, Xingyun Wang, Lin Zhou, Yongjun Zhang, Hongping Xia
Bronchopulmonary dysplasia (BPD), a common complication of premature birth, exerts considerable impact on the respiratory health of infants. This study aimed to identify the role of plasma metabolites in predicting respiratory outcomes in BPD-afflicted infants. This was a case-control study including 15 BPD premature infants and 15 gestational age and birth weight matched no-BPD preterm infants. Plasma
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Exploring the validity of the ASQ-SE for socio-emotional competency screening of a low-risk Asian cohort at 2 years of age Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-28 Pratibha Keshav Agarwal, Huichao Xie, Anu Sathyan Sathyapalan Rema, Ellen Ghim Hoon Tay, Michael J. Meaney, Keith M. Godfrey, Shirong Cai, Helen Yu Chen, Yap Seng Chong, Victor Samuel Rajadurai, Lourdes Mary Daniel
To assess the Ages & Stages Questionnaire: Social-Emotional (ASQ-SE)'s concurrent validity in a low-risk Singapore cohort and study its association with maternal mental health status. Concurrent validity of the parent-filled ASQ-SE with Child Behavior Checklist (CBCL1.5–5) was evaluated in 341 children at age 24 months. Data on maternal anxiety and depression were collected using the State-Trait Anxiety
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Impact of comprehensive quality improvement program on outcomes in very-low-birth-weight infants: A cluster-randomized controlled trial in Japan Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-26 Toshihiko Nishida, Satoshi Kusuda, Rintaro Mori, Katsuaki Toyoshima, Hideko Mitsuhashi, Hatoko Sasaki, Naohiro Yonemoto, Yumi Kono, Atsushi Uchiyama, Masanori Fujimura, INTACT Study Group
Differences in outcomes among neonatal intensive care units (NICUs) in Japan have been noted, prompting the need for quality improvement. To assess a comprehensive quality improvement program on outcomes in very-low-birth-weight (VLBW) infants. A cluster-randomized clinical trial. Forty hospitals and VLBW infants born in 2012–2014 and admitted to those hospitals were study subjects. The intervention
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Optimizing haemoglobin measurements in VLBW newborns: Insights from a comparative retrospective study Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-26 Andrea Calandrino, Carolina Montobbio, Irene Bonato, Gaia Cipresso, Francesco Vinci, Samuele Caruggi, Marcella Battaglini, Chiara Andreato, Federica Mongelli, Paolo Massirio, Giorgia Brigati, Diego Minghetti, Luca Antonio Ramenghi
Haemoglobin levels assessment is a crucial part of neonatal intensive care practice, the painful experience of repeated heel pricks and venepunctures blood sampling may negatively affect neonatal clinical course. To date the reliability of haemoglobin levels obtained by point-of-care testing (POCT) analysis if compared to standard blood cell count remains controversial. Retrospective study conducted
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Effect of antenatal micronutrient or antidepressant exposure on Brazelton neonatal behavioral assessment scale (NBAS) performance within one-month of birth Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-26 S.A. Campbell, H.A. Bradley, R.T. Mulder, J.M.T. Henderson, L. Dixon, L.C. Haslett, J.J. Rucklidge
Antenatal depression is a risk factor for poor infant outcomes. Broad-spectrum-micronutrients (vitamins and minerals) have shown efficacy in treating psychiatric symptoms in non-pregnant populations and are associated with reduced incidence of adverse birth outcomes, and improvements in neonatal development. We investigated the effects of treatment of antenatal depression with micronutrients above
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Challenges in clinical identification of right ventricular dysfunction in preterm infants with persistent pulmonary hypertension of the newborn Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-23 Faith Zhu, Caio Barbosa de Oliveira, Nada Mohsen, Ashraf Kharrat, Poorva Deshpande, Luc Mertens, Amish Jain
Right ventricular dysfunction, typically qualitatively diagnosed (Q-RVd) in preterm infants, requires echocardiography which is not always acutely available. We aimed to identify clinical indices of Q-RVd in very preterm infants (gestational age, GA <32 weeks) with persistent pulmonary hypertension of newborn (PPHN) and examine the reliability and validity of Q-RVd. Forty-seven infants with mean ± SD
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‘Baby Liberation’ – Developing and implementing an individualised, developmentally-supportive care bundle to critically unwell infants in an Australian Paediatric Intensive Care Unit Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-23 Bronagh McAlinden, Natasha Pool, Jane Harnischfeger, Michaela Waak, Miranda Campbell
Infants requiring high acuity care within a Paediatric Intensive Care Unit are at multifactorial risk of neurological injury to the immature brain, resulting in long-term developmental difficulties. In 2020, Queensland Children's Hospital implemented an individualised family-centred developmental care program, ‘Baby Liberation’, to address an identified service gap for critically unwell infants, aimed
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2D:4D ratio, alexithymia, impulsivity, aggression, and ADHD in men with opioid and methamphetamine use disorders: A comparative analysis with healthy controls Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-22 Merve Akkuş, Pınar Aydogan Avşar
Substance use disorder is an important mental health problem with increasing frequency. This study aims to investigate the 2D:4D ratio, Dr-I values (right-left differences), alexithymia, aggression, impulsivity, and attention deficit hyperactivity disorder (ADHD) symptoms in male patients with methamphetamine use disorder (MUD), opioid use disorder (OUD), and healthy controls. The study included a
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Electroencephalographic activity during direct breastfeeding and breast milk expression in primiparous mothers Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-20 M. Pérez-Hernández, J.P. García-Hernández, R.M. Hidalgo-Aguirre, M.A. Guevara, F.A. Robles-Aguirre, M. Hernández-González
Breastfeeding is recognized worldwide as the best option for infant feeding. Expressing breast milk is an alternative for mothers to provide their infants all the benefits of maternal milk. During breast milk expression, mothers receive a distinct kind of sensory stimulation, because there is no direct bodily or affective interaction with their infants, many women report feeling isolated, generating
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The psychometric properties and feasibility of the Alberta infant motor scale used in telehealth: A scoping review Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-15 Rafaela Silveira Passamani, Herika de Vargas Ciello, Beatriz Helena Brugnaro, Adriana Neves dos Santos
Background Telehealth can be a viable option for improving equitable access to early motor assessment for financially vulnerable individuals. Aim This review aimed to identify the psychometric properties of the Alberta Infant Motor Scale (AIMS) when applied via telehealth and assess its feasibility. Methods Papers were systematically retrieved from electronic databases until October 4, 2023. We included
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Attachment and mother-infant interactions in dyads with infants born full-term, moderate-to-late preterm, and very-to-extreme preterm Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-17 Marina Fuertes, Inês Martelo, Rita Almeida, Joana L. Gonçalves, Miguel Barbosa
Background The impact of prematurity status on attachment quality remains indeterminate. Some studies found no differences between infants born preterm (PT) and infants born full-term (FT), while other investigations present opposite results. Aims We aim to contribute to this body of research by studying mother-infant interactive behaviors and quality of attachment in 3 independent samples: Full-Term
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Application of desirability of outcome ranking to the milking in non-vigorous infants trial Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-05 Anup C. Katheria, Laure El ghormli, Madeline M. Rice, Rebecca A. Dorner, William A. Grobman, Scott R. Evans
Objectives Neonatal trials have traditionally used binary composite short-term (such as death or bronchopulmonary dysplasia) or longer-term (such as death or severe neurodevelopmental impairment) outcomes. We applied the Desirability Of Outcome Ranking (DOOR) method to rank the overall patient outcome by best (no morbidities) to worst (death). Study design Using a completed large multicenter trial
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Does parental mental health mediate the association between parents' perceived stress and parent-infant bonding during the early COVID-19 pandemic? Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-05 Carmen Power, Victoria Weise, Judith T. Mack, Marlene Karl, Susan Garthus-Niegel
Background The spread of the COVID-19 virus was declared a pandemic in March 2020. New restrictions such as ‘lockdowns’ and ‘social distancing’ created challenges for individuals' work-life balance, financial situation, family life, and physical and mental health. The global population's stress levels rose in response to these changes, leading to a widespread deterioration of mental health. One group
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Understanding Covid-19: Digit ratios and duration of oxygen therapy in hospitalized Covid-19 patients Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-05 Anna Kasielska-Trojan, Maciej Jabłkowski, Jolanta Białkowska-Warzecha, Oliwia Kwaśniewska, Bogusław Antoszewski
Background Covid-19 severity shows a sex difference (males>females) and progressive hypoxia among the most seriously affected. Digit ratios are sexually dimorphic and may be negatively-related to prenatal (2nd-to-4th digits' ratio; 2D:4D) and pubertal (3rd-to-5th digits' ratio; 3D:5D) testosterone. Oxygen therapy is important in Covid-19 treatment and low 2D:4D is linked to efficient oxygen metabolism
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Relationship between trunk control and gross motor development of infants in the first year of life: A systematic review Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-04 Kaitiana Martins da Silva, Raissa Felipe Pádua, Cristina dos Santos Cardoso de Sá, Raquel de Paula Carvalho
Objective to verify the relationship between the level of trunk control and the acquisition of gross motor skills in the first year of life. Methods a searching strategy was developed using the PICO tool and performed in the databases PubMed, Cochrane Library, Virtual Library in Health, Embase, and Scopus, from September 2020 to July 2022. The methodological quality of the articles was evaluated by
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Neonatal-onset pulmonary alveolar proteinosis is a phenotype associated with poor outcomes in surfactant protein-C disorder Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-04 Ryota Honjo, Kazutoshi Cho, Kahoko Hashimoto, Kenta Takeda, Yoshitaka Seto, Yosuke Kaneshi, Yuta Furuse, Atsushi Manabe
Background Surfactant protein C (SP-C) disorder is a major component of hereditary interstitial lung disease (HILD) among Japanese. The correlation between clinical outcomes and the phenotype/genotype of SP-C disorder has not been evaluated comprehensively. The current study aimed to evaluate the phenotype/genotype correlated with poor outcomes in patients with SP-C disorder. Methods Sequencing analysis
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Early red blood cell transfusion and the occurrence of intraventricular hemorrhage in very preterm infants Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-04 Aleksandra Skubisz, Linda S. de Vries, Sophie J. Jansen, Hilde van der Staaij, Enrico Lopriore, Sylke J. Steggerda
Background Preterm infants are at risk of developing both intraventricular hemorrhage (IVH) and anemia of prematurity. Several studies reported an association between early postnatal red blood cell (RBC) transfusion and IVH, however the timing and causality between these two remains unclear. Aims To describe the temporal sequence between administration of early RBC transfusion (within the first week
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The findings are probably due to reverse causation: Letter to the Editor regarding: Chehrazi M, Lanoue J, Ougham K, Moss B, Uthaya S, Modi N. Outcomes in very preterm infants receiving an exclusive human milk diet, or their own mother's milk supplemented with preterm formula. Early Hum. Dev. 2023;187 Early Hum. Dev. (IF 2.5) Pub Date : 2024-01-03 Keith J. Barrington
Abstract not available
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Ischemia modified albumin as a marker of hypoxia in preterm infants in the first week after birth Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-30 Martin van der Heide, Anneke C. Muller Kobold, Karin K.R. Koerts-Steijn, Christian V. Hulzebos, Jan B.F. Hulscher, Simon Eaton, Michael Orford, Arend F. Bos, Jan Koerts, Elisabeth M.W. Kooi
Background Tissue hypoxia remains a leading cause of morbidity and mortality in preterm infants. Current biomarkers often detect irreversible hypoxic cellular injury (i.e. lactate) and are non-specific. A new biomarker is needed which detects tissue hypoxia before irreversible damage occurs. Aims To investigate the relation between serum ischemia modified albumin (IMA), a marker of hypoxia; and analytic
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Hokkaido birth cohort study in Japan on the growth trajectory of children born with low birth weight until 7 years of age Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-26 Kritika Poudel, Sumitaka Kobayashi, Hiroyoshi Iwata, Maki Tojo, Takeshi Yamaguchi, Keiko Yamazaki, Naomi Tamura, Mariko Itoh, Taku Obara, Shinichi Kuriyama, Reiko Kishi
Background Low birth weight (LBW) is a significant global health concern with potential health risks and developmental implications for infants. Catch-up growth, an accelerated growth following an inhibition period, may partially compensate for growth deficits in LBW children. Aims This study investigated the prevalence of LBW and catch-up growth in height, weight, and body mass index (BMI) among LBW
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General movements assessment: A bibliometric analysis Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-21 Zhanna Zhussupova, Dinmukhamed Ayaganov, Latina Tekebayeva, Altynshash Jaxybayeva, Ayten Mamedbayli, Amin Tamadon, Gulmira Zharmakhanova
This bibliometric analysis provides an in-depth exploration of the scholarly landscape in the field of Prechtl General Movement Assessment (GMA) research, spanning the period from 1961 to 2023. It offers valuable insights into the evolutionary trajectory and global impact of GMA. The study employs a longitudinal approach, meticulously tracking trends in scholarly output, international collaborations
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Young adult outcomes following premature birth: A Western Australian experience Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-18 Cheryl A. Mackay, Caitlin Gray, Catherine Campbell, Mary J. Sharp
Background Childhood outcomes following preterm birth are widely published, however long-term adult outcomes are less well described. We aimed to determine the quality of life and burden of co-morbidities experienced by preterm-born young adults in Western Australia. Methods A retrospective observational study was conducted. Participants born at 23–33 weeks gestation cared for at King Edward Memorial
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Value of video-based education to enhance infant motor development Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-18 Nicole Kleffman, Kailey Snyder, Marlene Rosager Lund Pedersen, Jenny Dong, Angie Pereira-Burbach, Danae Dinkel
Background Parents play a vital role in promoting infant motor development and physical activity; however, there is little information available to parents on how to support healthy movement. Therefore, the purpose of this study was to assess the feasibility of implementing video-based education to improve infant physical activity and motor development. Methods This multiple case study consisted of
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Contributions of the light environment and co-sleeping to sleep consolidation into nighttime in early infants: A pilot study Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-22 Michiko Yoshida, Atsuko Ikeda, Hiroyuki Adachi
Background Sleep consolidation into nighttime is considered the primary goal of sleep development in early infants. However, factors contributing to sleep consolidation into nighttime remain unclear. Aim To clarify the influences of the light environment and nighttime co-sleeping on sleep consolidation into nighttime in early infants. Study design Cross-sectional study. Subjects and methods Sleep–wake
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Heart rate variability in school-age children born moderate-to-late preterm Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-21 Fabianne M.N.A. Dantas, Paulo A.F. Magalhães, Emilly C.N. Hora, Lívia B. Andrade, Emanuel S.C. Sarinho
Background Prematurity is associated with reduced cardiac autonomic function. This study aimed to investigate the heart rate variability (HRV) in school-age children born moderately to late preterm (MLPT). Methods This cross-sectional study investigated school-age children, aged 5 to 10 years, born moderate-to-late preterm. Electrocardiograms recordings were performed during fifteen-minutes. Time and
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Effects of SARS-CoV-2 gestational exposure and risk factors on neurodevelopment until 12 months: A prospective cohort study in Brazil Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-13 Gabriela Soutto Mayor Assumpção Pinheiro, Stela Maris Aguiar Lemos, Isadora de Araújo Martins, Gabriela Cintra Januário, Mila Lemos Cintra, Ana Vitória Silva Rodrigues Farias, Rafaela Martins dos Santos Oliveira, José Nélio Januário, Vivian Mara Gonçalves de Oliveira Azevedo, Aline Almeida Bentes, Claudia Regina Lindgren Alves
Background The effects of SARS-CoV-2 gestational exposure on child development remain inconclusive. Aims To analyze the effects of SARS-CoV-2 gestational exposure on neurodevelopment until 12 months. Study design Prospective cohort study conducted in five municipalities in Southeast Brazil from August 2021 to September 2022. Subjects Infants were recruited from a serological survey performed during
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Predictive value of General Movements Assessment for developmental delay at 18 months in children with complex congenital heart disease Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-08 Darlene C. Huisenga, Sacha la Bastide-van Gemert, Andrew H. Van Bergen, Jane K. Sweeney, Mijna Hadders-Algra
Background Infants with complex congenital heart disease are at increased risk of impaired fetal brain growth, brain injury, and developmental impairments. The General Movement Assessment (GMA) is a valid and reliable tool to predict cerebral palsy (CP), especially in preterm infants. Predictive properties of the GMA in infants with complex congenital heart disease (CCHD) are unknown. Aim To evaluate
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Association between intermittent hypoxemia and neurodevelopmental outcomes in extremely premature infants: A single-center experience Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-13 Faith Kim, David A. Bateman, Donna Garey, Nimrod Goldshtrom, Joseph R. Isler, Rakesh Sahni, Aaron Wallman-Stokes
Objective To describe the association between intermittent hypoxemic events (IHEs) and severe neurodevelopmental impairment (SNDI) or death in extremely premature infants. Study design Retrospective study of extremely premature infants 230/7–276/7 weeks gestational age (GA) and birthweight (BW) ≤1250 grams (g) admitted to a level IV neonatal intensive care unit (NICU) from 2013 to 2017. IHEs, defined
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Prevalence and risk factors associated with the need for surgical intervention due to necrotizing enterocolitis in very low birth weight infants Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-10 Maria Ailen Bruno, Maria Fernanda Galletti, Pablo H. Brener Dik, Gonzalo L. Mariani, Álvaro Gonzalez, Ricardo Nieto
Introduction Necrotizing enterocolitis (NEC) is one of the most common gastrointestinal emergencies affecting very low birth weight (VLBW) infants with an incidence of 6–15 %. Early recognition is crucial. Mortality is high and variable (30–50 %). Those requiring surgical intervention have a higher mortality rate than those who receive medical treatment. Objectives 1) To assess the prevalence of surgical
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Does base excess predict kidney injury in neonates with hypoxic-ischemic encephalopathy? Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-06 H. Gözde Kanmaz Kutman, Gülsüm Kadıoğlu Şimşek, Betül Siyah Bilgin, M. Şenol Akin, Fuat Emre Canpolat
In neonates with hypoxic-ischemic encephalopathy (HIE), we studied the correlation between cord blood base excess (BE) and kidney function. Among 225 infants, 29 % had oliguria. BE levels differed significantly between oliguric and non-oliguric infants (p < 0.01), with a negative correlation to kidney injury (r = −0.544, p < 0.01). BE < −18 had 85 % specificity and 76 % sensitivity in predicting kidney
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Prevalence and patterns of executive function, adaptive function, and behavioral outcomes in preschool and school age children with congenital diaphragmatic hernia Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-09 Enrico Danzer, Jane E. Schreiber, Casey Hoffman, Leny Mathew, Sabrina J. Flohr, Elizabeth Eppley, Sierra D. Land, Lisa Herkert, Natalie E. Rintoul, N. Scott Adzick, Holly L. Hedrick
Background Executive function, adaptive function, and behavioral outcomes in congenital diaphragmatic hernia (CDH) survivors have not been well studied. Aim To evaluate executive and neurobehavioral dysfunction in preschool and early school-aged children with CDH. Study design Retrospective cohort study. Subjects All eligible CDH survivors ages 3 to 7 years enrolled in our follow-up program between
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Assortative parenting and assortative cross-parenting: New views of parental preference for selected children Early Hum. Dev. (IF 2.5) Pub Date : 2023-12-01 Nancy L. Segal
Two novel parenting terms are introduced into the literature on parent-child relationships. The first term, assortative parenting, references a familiar, but poorly defined concept regarding parental affinity for a given child. The second term, assortative cross-parenting, denotes a previously unrecognized relationship phenomenon, namely parental attraction to a child who displays favored qualities
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Digit ratio and the femoral circumflex artery perforator: A sex-dependent association between the vascular system of the thigh and prenatal sex hormones? Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-29 Anna Kasielska-Trojan, Aneta Sitek, Mateusz Gabryszewski, Bogusław Antoszewski
Background The anterolateral thigh flap (ALTF) is a type of free flap which is commonly used in reconstructive surgery procedures and is based on the perforator from femoral circumflex artery. Some authors found that the location of the perforator differs between sexes. Objective To verify the influence of prenatal sex hormones (as measured by 2D:4D) on the morphology of the perforator of the descending
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Relationship of passive hypothermia during transport with the incidence of early multiorgan compromise in newborns with perinatal asphyxia Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-24 Gloria Troncoso, Sergio Agudelo-Pérez, Nicole Thorin Maldonado, Mateo Perdigón Becerra
Background Newborns with perinatal asphyxia can be born in institutions that cannot perform therapeutic hypothermia. Therefore, hypothermia should be initiated during transport using passive hypothermia. The effects of overcooling on mortality and multiorgan compromise in newborns with perinatal asphyxia subjected to passive hypothermia are poorly understood. Aims To evaluate the relationship between
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Birth weight discordance in very and extremely preterm twins and the risk of neonatal hearing loss Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-06 Paula van Dommelen, Paul H. Verkerk, Karin de Graaff-Korf, Henrica L.M. van Straaten
Objective Birth weight (BW) discordant twins have an increased risk of mortality and morbidity. We aimed to study the effect of BW discordance on the risk of neonatal hearing loss (NHL) in very and extremely preterm twins. Study design Results of the nationwide newborn hearing screening program in Dutch Neonatal Intensive Care Units and diagnostic examination were centrally registered between 2003
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Hemodynamic evaluation of extremely low birth weight infants during the first 7 days of life Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-08 Sun Mee Tan, Hidehiko Nakanishi, Shuji Ishida, Yukako Kosaka, Rika Sekiya, Kouhei Kawada, Mari Ooka
Background and aim We aimed to investigate the hemodynamic status of extremely low birth weight (ELBW) infants during the transitional period under intensive management. Methods This retrospective cohort study analyzed left ventricular ejection fraction (LVEF), left ventricular end-systolic wall stress (ESWS), left ventricular internal dimension in diastole (LVIDd), and mean arterial pressure (MAP)
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The critical role of technologies in neonatal care Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-04 Syed Taha, Rosalind B. Simpson, Don Sharkey
Neonatal care has made significant advances in the last few decades. As a result, mortality and morbidity in high-risk infants, such as extremely preterm infants or those infants with birth-related brain injury, has reduced significantly. Many of these advances have been facilitated or delivered through development of medical technologies allowing clinical teams to be better supported with the care
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Association between early-life antibiotics use and the risk of attention-deficit/hyperactivity disorder: A real-world evidence study Early Hum. Dev. (IF 2.5) Pub Date : 2023-10-29 Chih-Kang Lin, Ya-Chun Tseng, Hsing-Yu Hsu, Tung-Han Tsai, Kuang-Hua Huang
Background Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. Recently, children using antibiotics showed an increased incidence of neurodevelopmental disorders. Aims The purpose of this study was to investigate the association between antibiotics use and the risk of ADHD in children. Study design Population-based retrospective cohort study. Subjects The Taiwan
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Is prenatal testosterone-estrogen balance related to critical shoulder angle? Early Hum. Dev. (IF 2.5) Pub Date : 2023-11-03 Haluk Yaka, Yahaya Baako, Mustafa Özer, Ulunay Kanatli
Background The 2D:4D ratio (an indicator of prenatal testosterone-estrogen balance) is the ratio of the second finger length to the fourth finger length. We hypothesized that low 2D:4D values indicating high prenatal testosterone exposure may be associated with increased critical shoulder angle (CSA). Aims The aim of this study was to evaluate the relationship between CSA and 2D:4D ratio. Methods Meeting