当前期刊：
Nature Structural & Molecular Biology
Go to
current issue
加入关注
本刊介绍/投稿指南
催更
样式： 排序： IF: - GO 导出 标记为已读
Go to
current issue
加入关注
本刊介绍/投稿指南
催更
样式： 排序： IF: - GO 导出 标记为已读
-
Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-09 Sicong Zhang, Robert G. Roeder
-
Author Correction: Unwinding of a eukaryotic origin of replication visualized by cryo-EM. Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-09 Sarah S Henrikus,Marta H Gross,Oliver Willhoft,Thomas Pühringer,Jacob S Lewis,Allison W McClure,Julia F Greiwe,Giacomo Palm,Andrea Nans,John F X Diffley,Alessandro Costa
-
Exocyst stimulates multiple steps of exocytic SNARE complex assembly and vesicle fusion Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-06 Chanwoo Lee, Dante Lepore, Seung-Hak Lee, Tae Gyun Kim, Natasha Buwa, Jongchan Lee, Mary Munson, Tae-Young Yoon
-
Distinct stabilization of the human T cell leukemia virus type 1 immature Gag lattice Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-06 Martin Obr, Mathias Percipalle, Darya Chernikova, Huixin Yang, Andreas Thader, Gergely Pinke, Dario Porley, Louis M. Mansky, Robert A. Dick, Florian K. M. Schur
-
Pseudouridine guides germline small RNA transport and epigenetic inheritance Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-06 Rowan P. Herridge, Jakub Dolata, Valentina Migliori, Cristiane de Santis Alves, Filipe Borges, Andrea J. Schorn, Frédéric van Ex, Ann Lin, Mateusz Bajczyk, Jean-Sebastien Parent, Tommaso Leonardi, Alan Hendrick, Tony Kouzarides, Robert A. Martienssen
-
Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-03 Kevin Michalski, Taha Abdulla, Sam Kleeman, Lars Schmidl, Ricardo Gómez, Noriko Simorowski, Francesca Vallese, Harald Prüss, Manfred Heckmann, Christian Geis, Hiro Furukawa
-
Shieldin and CST co-orchestrate DNA polymerase-dependent tailed-end joining reactions independently of 53BP1-governed repair pathway choice Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-03 Ashleigh King, Pia I. Reichl, Jean S. Metson, Robert Parker, Daniella Munro, Catarina Oliveira, Lucia Sommerova, Jordan R. Becker, Daniel Biggs, Chris Preece, Benjamin Davies, J. Ross Chapman
-
Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-03 Han Wang, Chun Xie, Bo Deng, Jingjun Ding, Na Li, Zengwei Kou, Mengmeng Jin, Jie He, Qinrui Wang, Han Wen, Jinbao Zhang, Qinming Zhou, Sheng Chen, Xiangjun Chen, Ti-Fei Yuan, Shujia Zhu
-
Structural insight into synergistic activation of human 3-methylcrotonyl-CoA carboxylase Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-09-02 Jiayue Su, Xuyang Tian, Hang Cheng, Desheng Liu, Ziyi Wang, Shan Sun, Hong-Wei Wang, Sen-Fang Sui
-
Dynamics of an epigenetic regulator on chromatin observed at the single-molecule level Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-22
-
Structural basis for lipid transfer by the ATG2A–ATG9A complex Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-22 Yang Wang, Selma Dahmane, Rujuan Ti, Xinyi Mai, Lizhe Zhu, Lars-Anders Carlson, Goran Stjepanovic
-
Putting together pieces of the LIN28A pathway puzzle Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-21 Alperen Yilmaz, Gulben Gurhan, Jacob H. Hanna
-
Differential dynamics specify MeCP2 function at nucleosomes and methylated DNA Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-20 Gabriella N. L. Chua, John W. Watters, Paul Dominic B. Olinares, Masuda Begum, Lauren E. Vostal, Joshua A. Luo, Brian T. Chait, Shixin Liu
-
Topoisomerase-modulated genome-wide DNA supercoiling domains colocalize with nuclear compartments and regulate human gene expression Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-16 Qian Yao, Linying Zhu, Zhen Shi, Subhadra Banerjee, Chongyi Chen
-
A PRE loop at the dac locus acts as a topological chromatin structure that restricts and specifies enhancer–promoter communication Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-16 Sandrine Denaud, Marion Bardou, Giorgio-Lucio Papadopoulos, Stefan Grob, Marco Di Stefano, Gonzalo Sabarís, Marcelo Nollmann, Bernd Schuettengruber, Giacomo Cavalli
-
Structural plasticity of bacterial ESCRT-III protein PspA in higher-order assemblies Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-16 Benedikt Junglas, Esther Hudina, Philipp Schönnenbeck, Ilona Ritter, Anja Heddier, Beatrix Santiago-Schübel, Pitter F. Huesgen, Dirk Schneider, Carsten Sachse
-
How protons shape AMPA receptor structure, function and diffusion at the synapse Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-13
-
Proton-triggered rearrangement of the AMPA receptor N-terminal domains impacts receptor kinetics and synaptic localization Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-13 Josip Ivica, Nejc Kejzar, Hinze Ho, Imogen Stockwell, Viktor Kuchtiak, Alexander M. Scrutton, Terunaga Nakagawa, Ingo H. Greger
-
Structural basis of LRPPRC–SLIRP-dependent translation by the mitoribosome Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-12 Vivek Singh, J. Conor Moran, Yuzuru Itoh, Iliana C. Soto, Flavia Fontanesi, Mary Couvillion, Martijn A. Huynen, L. Stirling Churchman, Antoni Barrientos, Alexey Amunts
-
Sex chromosome-encoded protein homologs: current progress and open questions Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-09 Michael C. Owens, Amber Yanas, Kathy Fange Liu
-
Structural basis of RfaH-mediated transcription–translation coupling Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-08 Vadim Molodtsov, Chengyuan Wang, Jing Zhang, Jason T. Kaelber, Gregor Blaha, Richard H. Ebright
-
Structural basis for processive daughter-strand synthesis and proofreading by the human leading-strand DNA polymerase Pol ε Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-08-07 Johann J. Roske, Joseph T. P. Yeeles
-
Identifying nature’s smallest fractals Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-30 Kelli L. Hvorecny
-
Dissecting the mechanism of CRISPR–Cas technologies to design efficient biotechnologies Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-26 Jasleen Gill
CRISPR–Cas enzymes have enabled us to manipulate the genetic code with unparalleled precision and efficiency. Here I explore the structural and biochemical intricacies that govern the functionality of CRISPR–Cas technologies, emphasizing the need for a nuanced mechanistic understanding to overcome current limitations and pave the way for safer and more effective genome-editing applications in medicine
-
The cyanobacterial protein VIPP1 forms ESCRT-III-like structures on lipid bilayers Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-26 Sichen Pan, Karin Gries, Benjamin D. Engel, Michael Schroda, Christoph A. Haselwandter, Simon Scheuring
-
Structural basis for activity switching in polymerases determining the fate of let-7 pre-miRNAs Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-25 Gangshun Yi, Mingda Ye, Loic Carrique, Afaf El-Sagheer, Tom Brown, Chris J. Norbury, Peijun Zhang, Robert J. C. Gilbert
-
Poised PABP–RNA hubs implement signal-dependent mRNA decay in development Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-25 Miha Modic, Klara Kuret, Sebastian Steinhauser, Rupert Faraway, Emiel van Genderen, Igor Ruiz de Los Mozos, Jona Novljan, Žiga Vičič, Flora C. Y. Lee, Derk ten Berge, Nicholas M. Luscombe, Jernej Ule
-
Genome dilution by cell growth drives starvation-like proteome remodeling in mammalian and yeast cells Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-24 Michael C. Lanz, Shuyuan Zhang, Matthew P. Swaffer, Inbal Ziv, Luisa Hernández Götz, Jacob Kim, Frank McCarthy, Daniel F. Jarosz, Joshua E. Elias, Jan M. Skotheim
-
Structural and mechanistic insights into Streptococcus pneumoniae NADPH oxidase Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-22 Victor R. A. Dubach, Pablo San Segundo-Acosta, Bonnie J. Murphy
-
The ribosome termination complex remodels release factor RF3 and ejects GDP Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-19 Li Li, Mariia Yu. Rybak, Jinzhong Lin, Matthieu G. Gagnon
-
Structural basis of NEAT1 lncRNA maturation and menRNA instability Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-18 Ilias Skeparnias, Jinwei Zhang
-
The power of scientific collaborations and the future of structural biology Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-15 Pedro Beltrao
The idea of a scientific discovery is often linked to the eureka moment of a lone scientist, which then transforms our thinking. However, scientific discoveries are never made by individuals in isolation. They build on the work of countless researchers, and often require interdisciplinary and collaborative teams of researchers.
-
A roadmap for ribosome assembly in human mitochondria Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-11 Elena Lavdovskaia, Elisa Hanitsch, Andreas Linden, Martin Pašen, Venkatapathi Challa, Yehor Horokhovskyi, Hanna P. Roetschke, Franziska Nadler, Luisa Welp, Emely Steube, Marleen Heinrichs, Mandy Mong-Quyen Mai, Henning Urlaub, Juliane Liepe, Ricarda Richter-Dennerlein
-
Resolving chaperone-assisted protein folding on the ribosome at the peptide level Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-10 Thomas E. Wales, Aleksandra Pajak, Alžběta Roeselová, Santosh Shivakumaraswamy, Steven Howell, Svend Kjær, F. Ulrich Hartl, John R. Engen, David Balchin
-
Obscure DNA sequences unveil a new cancer target Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-08 Agnel Sfeir
-
AlphaFold3 takes a step toward decoding molecular behavior and biological computation Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-08 Rohit Roy, Hashim M. Al-Hashimi
-
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-08 Sven M. Lange, Matthew R. McFarland, Frederic Lamoliatte, Thomas Carroll, Logesvaran Krshnan, Anna Pérez-Ràfols, Dominika Kwasna, Linnan Shen, Iona Wallace, Isobel Cole, Lee A. Armstrong, Axel Knebel, Clare Johnson, Virginia De Cesare, Yogesh Kulathu
-
Cryo-EM structures of γ-TuRC reveal molecular insights into microtubule nucleation Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-02 Léa Mammri, Paul T. Conduit
-
cBAF generates subnucleosomes that expand OCT4 binding and function beyond DNA motifs at enhancers Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-02 Marina C. Nocente, Anida Mesihovic Karamitsos, Emilie Drouineau, Manon Soleil, Waad Albawardi, Cécile Dulary, Florence Ribierre, Hélène Picaud, Olivier Alibert, Joël Acker, Marie Kervella, Jean-Christophe Aude, Nick Gilbert, Françoise Ochsenbein, Sophie Chantalat, Matthieu Gérard
-
Structural basis of MALAT1 RNA maturation and mascRNA biogenesis Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-02 Ilias Skeparnias, Charles Bou-Nader, Dimitrios G. Anastasakis, Lixin Fan, Yun-Xing Wang, Markus Hafner, Jinwei Zhang
-
Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-01 Ruth M. Saecker, Andreas U. Mueller, Brandon Malone, James Chen, William C. Budell, Venkata P. Dandey, Kashyap Maruthi, Joshua H. Mendez, Nina Molina, Edward T. Eng, Laura Y. Yen, Clinton S. Potter, Bridget Carragher, Seth A. Darst
-
Asymmetric apical domain states of mitochondrial Hsp60 coordinate substrate engagement and chaperonin assembly Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-01 Julian R. Braxton, Hao Shao, Eric Tse, Jason E. Gestwicki, Daniel R. Southworth
-
Single-base tiled screen unveils design principles of PspCas13b for potent and off-target-free RNA silencing Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-07-01 Wenxin Hu, Amit Kumar, Syed Faraz Ahmed, Shijiao Qi, David K. G. Ma, Honglin Chen, Gurjeet J. Singh, Joshua M. L. Casan, Michelle Haber, Ilia Voskoboinik, Matthew R. McKay, Joseph A. Trapani, Paul G. Ekert, Mohamed Fareh
-
The tRNA methyltransferase METTL6 requires seryl-tRNA synthetase for tRNASer targeting Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-25
-
Structural basis of tRNA recognition by the m3C RNA methyltransferase METTL6 in complex with SerRS seryl-tRNA synthetase Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-25 Philipp Throll, Luciano G. Dolce, Palma Rico-Lastres, Katharina Arnold, Laura Tengo, Shibom Basu, Stefanie Kaiser, Robert Schneider, Eva Kowalinski
-
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16 Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-25 Huasong Ai, Zaozhen He, Zhiheng Deng, Guo-Chao Chu, Qiang Shi, Zebin Tong, Jia-Bin Li, Man Pan, Lei Liu
-
Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-25 Elias Adriaenssens, Thanh Ngoc Nguyen, Justyna Sawa-Makarska, Grace Khuu, Martina Schuschnig, Stephen Shoebridge, Marvin Skulsuppaisarn, Emily Maria Watts, Kitti Dora Csalyi, Benjamin Scott Padman, Michael Lazarou, Sascha Martens
-
Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-19 Duc-Duy Vu, Alessio Bonucci, Manon Brenière, Metztli Cisneros-Aguirre, Philippe Pelupessy, Ziqing Wang, Ludovic Carlier, Guillaume Bouvignies, Patricia Cortes, Aneel K. Aggarwal, Martin Blackledge, Zoher Gueroui, Valérie Belle, Jeremy M. Stark, Mauro Modesti, Fabien Ferrage
-
Structures of synaptic vesicle protein 2A and 2B bound to anticonvulsants Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-19 Anshumali Mittal, Matthew F. Martin, Elena J. Levin, Christopher Adams, Meng Yang, Laurent Provins, Adrian Hall, Martin Procter, Marie Ledecq, Alexander Hillisch, Christian Wolff, Michel Gillard, Peter S. Horanyi, Jonathan A. Coleman
-
Structure of the poxvirus core Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-18 Fasséli Coulibaly
-
Structural basis for the dynamic chaperoning of disordered clients by Hsp90 Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-18 Xiaozhan Qu, Shuo Zhao, Chanjuan Wan, Lei Zhu, Tuo Ji, Paolo Rossi, Junfeng Wang, Charalampos G. Kalodimos, Chao Wang, Weiya Xu, Chengdong Huang
-
Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-18 Qian Li, Jun Zhang, Cory Haluska, Xiang Zhang, Lei Wang, Guangfeng Liu, Zhaoning Wang, Duo Jin, Tong Cheng, Hongxia Wang, Yuan Tian, Xiangxi Wang, Lei Sun, Xiaolan Zhao, Zhenguo Chen, Lanfeng Wang
-
The human ATAD5 has evolved unique structural elements to function exclusively as a PCNA unloader Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-13 Feng Wang, Qing He, Nina Y. Yao, Michael E. O’Donnell, Huilin Li
-
Efficient selenium use by PRDX6 suppresses iron toxicity and ferroptosis Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-12
-
PRDX6 augments selenium utilization to limit iron toxicity and ferroptosis Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-12 Hiroaki Fujita, Yu-ki Tanaka, Seiryo Ogata, Noriyuki Suzuki, Sota Kuno, Uladzimir Barayeu, Takaaki Akaike, Yasumitsu Ogra, Kazuhiro Iwai
-
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-12 Hossein Batebi, Guillermo Pérez-Hernández, Sabrina N. Rahman, Baoliang Lan, Antje Kamprad, Mingyu Shi, David Speck, Johanna K. S. Tiemann, Ramon Guixà-González, Franziska Reinhardt, Peter F. Stadler, Makaía M. Papasergi-Scott, Georgios Skiniotis, Patrick Scheerer, Brian K. Kobilka, Jesper M. Mathiesen, Xiangyu Liu, Peter W. Hildebrand
-
Author Correction: MYC phase separation selectively modulates the transcriptome. Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-12 Junjiao Yang,Chan-I Chung,Jessica Koach,Hongjiang Liu,Ambuja Navalkar,Hao He,Zhimin Ma,Qian Zhao,Xiaoyu Yang,Liang He,Tanja Mittag,Yin Shen,William A Weiss,Xiaokun Shu
-
-
The structure of the human 80S ribosome at 1.9 Å resolution reveals the molecular role of chemical modifications and ions in RNA Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-06 Samuel Holvec, Charles Barchet, Antony Lechner, Léo Fréchin, S. Nimali T. De Silva, Isabelle Hazemann, Philippe Wolff, Ottilie von Loeffelholz, Bruno P. Klaholz
-
XIST dampens X chromosome activity in a SPEN-dependent manner during early human development Nat. Struct. Mol. Biol. (IF 12.5) Pub Date : 2024-06-04 Charbel Alfeghaly, Gaël Castel, Emmanuel Cazottes, Madeleine Moscatelli, Eva Moinard, Miguel Casanova, Juliette Boni, Kasturi Mahadik, Jenna Lammers, Thomas Freour, Louis Chauviere, Carla Piqueras, Ruben Boers, Joachim Boers, Joost Gribnau, Laurent David, Jean-François Ouimette, Claire Rougeulle
更新日期：2024-09-03
京公网安备 11010802027423号