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From local APP expression to network dysfunction Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-29 Darran Yates
In mice, localized mutant APP expression in the CA3 hippocampal region leads to progressive network dysfunction and hippocampus-dependent memory deficits.
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Publisher Correction: The transition to motherhood: linking hormones, brain and behaviour. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Camila Servin-Barthet,Magdalena Martínez-García,Clara Pretus,Maria Paternina-Die,Anna Soler,Olha Khymenets,Óscar J Pozo,Benedetta Leuner,Oscar Vilarroya,Susana Carmona
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Human neuronal maturation comes of age: cellular mechanisms and species differences Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-23 Jenelle L. Wallace, Alex A. Pollen
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Low-frequency neural parsing of hierarchical linguistic structures. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Nai Ding
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Reply to 'Low-frequency neural parsing of hierarchical linguistic structures'. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-12-01 Nina Kazanina,Alessandro Tavano
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Playing tag at the axon Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-15 Lisa Heinke
A new biotinylation-based approach identifies previously unknown cell surface proteins of the axonal initial segment (AIS) and shows a role for contactin-1 in assembly of the AIS extracellular matrix.
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Sometimes science needs a stubborn mind: the discovery of dopamine Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-14 Federica De Lazzari
Federica De Lazzari describes Arvid Carlsson’s 1957 paper, which provided evidence for the importance of dopamine in brain function.
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Mapping cilia connections in the human brain Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-13 Katherine Whalley
The organization and diversity of neuronal and glial primary cilia and their connectivity in the human cortex is characterized in detail.
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Avoiding bias in fluorescence sensor readout Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-10 Dmitri A. Rusakov
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Reliable social switch Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-08 Jake Rogers
The macaque homologue of the dorsal medial prefrontal cortex tracks the reliability of social information and determines whether this information is used to guide choices during decision making.
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Caught in a trap Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-02 Katherine Whalley
Ketamine is ‘trapped’ in the pores of NMDA receptors in the lateral habenula, mediating sustained antidepressant effects in mice.
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Boundary deprivation does not prevent grid cell maturation Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Caroline Barranco
Grid cells develop in rats soon after they leave the nest. Here, Ulsaker-Janke et al. show that preventing exposure to straight boundaries from birth delays, but does not prevent, grid cell maturation in adult rats.
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Coding number estimates Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-31 Darran Yates
A new study shows that, in a numerical judgement task, individuals show differences in neuronal coding of numbers below and above approximately four in the medial temporal lobe.
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Reply to 'What oscillations can do for syntax depends on your theory of structure building'. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Nina Kazanina,Alessandro Tavano
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What oscillations can do for syntax depends on your theory of structure building. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Cas W Coopmans,Anna Mai,Sophie Slaats,Hugo Weissbart,Andrea E Martin
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When linguistic dogma rejects a neuroscientific hypothesis. Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-11-01 Chia-Wen Lo,Lena Henke,Jordi Martorell,Lars Meyer
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How deep is the brain? The shallow brain hypothesis Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-27 Mototaka Suzuki, Cyriel M. A. Pennartz, Jaan Aru
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Detection, processing and reinforcement of social cues: regulation by the oxytocin system Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-27 Rohit Menon, Inga D. Neumann
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Data sharing in neuroimaging: experiences from the BIDS project Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-24 Melanie Ganz, Russell A. Poldrack
Data sharing is an essential component of open science practice. The Brain Imaging Data Structure project has pioneered a way to organize neuroimaging and behavioural data that enables easy sharing and reuse. We present experiences from the BIDS project and highlight how standards can promote open science.
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Neuron–oligodendroglial interactions in health and malignant disease Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-19 Kathryn R. Taylor, Michelle Monje
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Give and take Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-18 Sian Lewis
Following synaptic vesicle exocytosis, synaptotagmin 1 recruits a lipid signalling pathway within the presynaptic plasma membrane that drives local dynamin recruitment and membrane retrieval by endocytosis, thus maintaining membrane homeostasis.
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Towards a biologically annotated brain connectome Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-17 Vincent Bazinet, Justine Y. Hansen, Bratislav Misic
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Examining the role of the locus coeruleus in activating cortical astrocytes Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-06 Nathan Anthony Smith
In this Journal Club, Nathan Anthony Smith discusses a 2008 paper that documented a link between the noradrenergic modulatory network in the locus coeruleus and cortical astrocytes in vivo.
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Reconstructing computational system dynamics from neural data with recurrent neural networks Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-04 Daniel Durstewitz, Georgia Koppe, Max Ingo Thurm
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Parenting circuit triggered by infant cries Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-03 Katherine Whalley
A study dissects the neural circuit through which pup cries induce oxytocin release and maternal behaviour in mice.
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Is song processing distinct and special in the auditory cortex? Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-10-02 Ilana Harris, Efe C. Niven, Alex Griffin, Sophie K. Scott
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Excitation–transcription coupling, neuronal gene expression and synaptic plasticity Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-29 Huan Ma, Houda G. Khaled, Xiaohan Wang, Nataniel J. Mandelberg, Samuel M. Cohen, Xingzhi He, Richard W. Tsien
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A structural function for CaMKII Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-28 Darran Yates
A study reports that in the mouse hippocampus, the induction of long-term potentiation is dependent on the structural functions of CaMKII and not its enzymatic activity.
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Hormonal gatekeeper of distinct social behaviours Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-28 Jake Rogers
A juvenile hormone-degrading enzyme localized in the insect equivalent of the blood–brain barrier governs which social role, forager or soldier, worker carpenter ants fulfil.
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Angiogenesis in the eye Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-28 Sian Lewis
During retinal development in the mouse, angiogenesis was unexpectedly found to depend on temporally restricted dopamine production by retinal ganglion cells, rather than by canonical retinal dopamine neurons.
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Predicting post-COVID-19 cognitive deficits Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-28 Darran Yates
A study identified two different blood biomarker profiles in people hospitalized for COVID-19 that predicted later cognitive deficits.
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Restoring speech Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-22 Katherine Whalley
Two papers report the development of high performance brain–computer interfaces that can decode speech from cortical activity.
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Rewinding reward Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-20 Sian Lewis
Increasing levels of glial-derived neurotrophic factor using a gene-therapy approach in a macaque model of alcohol use disorder resulted in a lower tendency to relapse into alcohol consumption after a period of abstinence.
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Defensive responses: behaviour, the brain and the body Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-20 Yu-Ting Tseng, Bernhard Schaefke, Pengfei Wei, Liping Wang
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Reply to ‘When linguistic dogma rejects a neuroscientific hypothesis’ Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-09-11 Nina Kazanina, Alessandro Tavano
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Astrocyte engulfment Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-29 Sian Lewis
The stress associated with early-life social deprivation in mice results in corticosterone-driven overstimulation of cortical synapse removal by astrocytes and behavioural abnormalities in mature animals.
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Mapping mating circuits Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-25 Darran Yates
A new study reveals a neural circuit that regulates innate sexual behaviour in male mice.
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Central regulation of stress-evoked peripheral immune responses Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-25 Kenny L. Chan, Wolfram C. Poller, Filip K. Swirski, Scott J. Russo
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A biophysical perspective on the resilience of neuronal excitability across timescales Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-24 Shimon Marom, Eve Marder
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Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-24 Jacob W. Vogel, Nick Corriveau-Lecavalier, Nicolai Franzmeier, Joana B. Pereira, Jesse A. Brown, Anne Maass, Hugo Botha, William W. Seeley, Dani S. Bassett, David T. Jones, Michael Ewers
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The transition to motherhood: linking hormones, brain and behaviour Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-23 Camila Servin-Barthet, Magdalena Martínez-García, Clara Pretus, Maria Paternina-Pie, Anna Soler, Olha Khymenets, Óscar J. Pozo, Benedetta Leuner, Oscar Vilarroya, Susana Carmona
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Cerebrospinal fluid-contacting neurons: multimodal cells with diverse roles in the CNS Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-09 Claire Wyart, Martin Carbo-Tano, Yasmine Cantaut-Belarif, Adeline Orts-Del’Immagine, Urs L. Böhm
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Losing sleep in heart disease Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-08-08 Katherine Whalley
Cardiac disease drives the denervation of the pineal gland, resulting in a loss of neural control of melatonin release and disrupted sleep–wake patterns.
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Network models to enhance the translational impact of cross-species studies Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-31 Julia K. Brynildsen, Kanaka Rajan, Michael X. Henderson, Dani S. Bassett
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Planning projections Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-28 Sian Lewis
During cortical development, direct neurogenesis was found to generate key glutamatergic projection neuron subclasses and indirect neurogenesis generated and amplified specific subpopulations within these subclasses.
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Co-released with opposing actions but coordinated timescales Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-27 Jake Rogers
A co-released inhibitory neurotransmitter and stimulatory neuropeptide are shown to act on different timescales to enhance circuit output and optimize behaviour.
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GABA tone regulation and its cognitive functions in the brain Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-26 Wuhyun Koh, Hankyul Kwak, Eunji Cheong, C. Justin Lee
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Myelin under attack endangers axons Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-18 Katherine Whalley
Findings suggest that the presence of a myelin sheath increases an axon’s vulnerability in autoimmune conditions.
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Brain network communication: concepts, models and applications Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-12 Caio Seguin, Olaf Sporns, Andrew Zalesky
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Gut macrophages shape and sustain the enteric nervous system Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-03 Katherine Whalley
Gut-resident macrophages are shown to have roles in circuit refinement and maintenance in the mouse enteric nervous system.
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Controlling corticosterone Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-03 Sian Lewis
The increase in blood corticosterone triggered by the release of proinflammatory cytokines is shown to involve vagal regulation of a parabrachial nucleus–paraventricular nucleus pathway.
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The hypothesis of fundal cognition Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-07-03 Kevin S. Weiner
Understanding how the brain organizes information into functional representations and networks that support flexible cognitive behaviour is a major goal in neuroscience. In a 1994 paper, Markowitsch and Tulving identified a relationship between functional activations (observed by positron emission tomography (PET)) and the deepest points (fundi) in the indentations (sulci) of the human cerebral cortex
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Interactions between rodent visual and spatial systems during navigation Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-28 Aman B. Saleem, Laura Busse
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Unpicking the antidepressant actions of psychedelics Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-19 Katherine Whalley
The binding of psychedelics to the BDNF receptor TrkB boosts plasticity in cultured neurons and underlies the antidepressant-like effects of these compounds in mice.
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Alternative splicing in neurodegenerative disease and the promise of RNA therapies Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-19 David Nikom, Sika Zheng
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Assessments of dentate gyrus function: discoveries and debates Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-14 Mia Borzello, Steve Ramirez, Alessandro Treves, Inah Lee, Helen Scharfman, Craig Stark, James J. Knierim, Lara M. Rangel
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Unfolding cognitive decline mechanisms Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-02 Sian Lewis
The number of neural stem cells in the brain decreases with age, which in the dentate gyrus of older mice is associated with a lower SIRT7-mediated mitochondrial unfolded protein response and reduced neural stem cell maintenance and neurogenesis.
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Roles and regulation of microglia activity in multiple sclerosis: insights from animal models Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-06-02 Félix Distéfano-Gagné, Sara Bitarafan, Steve Lacroix, David Gosselin
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Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-05-31 Eva-Maria Krämer-Albers, Hauke B. Werner
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Non-invasive continuous language decoding Nat. Rev. Neurosci. (IF 34.7) Pub Date : 2023-05-30 Jake Rogers
A brain–computer interface can decode semantic representations of perceived and imagined stimuli at the level of words and phrases from functional MRI recordings of brain activity.