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Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice Dev. Cell (IF 13.417) Pub Date : 2022-08-16 Jianjian Zhu, Rashmi Patel, Anna Trofka, Brian D. Harfe, Susan Mackem
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The spatiotemporal dynamics of microglia across the human lifespan Dev. Cell (IF 13.417) Pub Date : 2022-08-16 David A. Menassa, Tim A.O. Muntslag, Maria Martin-Estebané, Liam Barry-Carroll, Mark A. Chapman, Istvan Adorjan, Teadora Tyler, Bethany Turnbull, Matthew J.J. Rose-Zerilli, James A.R. Nicoll, Zeljka Krsnik, Ivica Kostovic, Diego Gomez-Nicola
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VAB-8 stops dynein in its tracks to regulate synaptic delivery Dev. Cell (IF 13.417) Pub Date : 2022-08-08 Sierra D. Palumbos, Erika L.F. Holzbaur
How synaptogenic signals trigger the targeted delivery of synaptic material is a fundamental question in neuroscience. In this issue of Developmental Cell, Balseiro-Gomez et al. identify a mechanism through which local synatogenic pathways control synaptic cargo delivery.
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N6-adenomethylation of GsdmC is essential for Lgr5+ stem cell survival to maintain normal colonic epithelial morphogenesis Dev. Cell (IF 13.417) Pub Date : 2022-08-01 Jie Du, Rajesh Sarkar, Yan Li, Lei He, Wenjun Kang, Wang Liao, Weicheng Liu, Tivoli Nguyen, Linda Zhang, Zifeng Deng, Urszula Dougherty, Sonia S. Kupfer, Mengjie Chen, Joel Pekow, Marc Bissonnette, Chuan He, Yan Chun Li
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Variability of cross-tissue X-chromosome inactivation characterizes timing of human embryonic lineage specification events Dev. Cell (IF 13.417) Pub Date : 2022-07-31 Jonathan M. Werner, Sara Ballouz, John Hover, Jesse Gillis
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A robust and tunable system for targeted cell ablation in developing embryos Dev. Cell (IF 13.417) Pub Date : 2022-07-31 Zahra Labbaf, Kleio Petratou, Laura Ermlich, Wilko Backer, Katsiaryna Tarbashevich, Michal Reichman-Fried, Stefan Luschnig, Stefan Schulte-Merker, Erez Raz
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Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter Dev. Cell (IF 13.417) Pub Date : 2022-07-31 Emily E. Fink, Surbhi Sona, Uyen Tran, Pierre-Emmanuel Desprez, Matthew Bradley, Hong Qiu, Mohamed Eltemamy, Alvin Wee, Madison Wolkov, Marlo Nicolas, Booki Min, Georges-Pascal Haber, Oliver Wessely, Byron H. Lee, Angela H. Ting
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Charting the human disease condensate dysregulome Dev. Cell (IF 13.417) Pub Date : 2022-07-27 Bappaditya Chandra, Richard Kriwacki
Although it is understood that myriad proteins function in cells within biomolecular condensates, it is unclear how protein condensation is altered in human disease. In this issue of Developmental Cell, Banani et al. show that mutations in disease-associated proteins may map to phase-separation-prone regions and thereby alter condensate formation.
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“Fateful” encounter: Lineage tracing meets phylogeny to unravel mysteries of cancer progression Dev. Cell (IF 13.417) Pub Date : 2022-07-27 Wing Hing Wong, Christina Curtis
In a recent issue of Cell, Yang et al. utilize evolvable cellular barcodes to investigate the evolutionary trajectories of murine lung adenocarcinoma. Reconstructing the life histories of these tumors based on cellular barcodes reveals stringent selection and phenotypic differences across subclonal lineages.
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Organ-specific COP1 control of BES1 stability adjusts plant growth patterns under shade or warmth Dev. Cell (IF 13.417) Pub Date : 2022-07-27 Cecilia Costigliolo Rojas, Luciana Bianchimano, Jeonghwa Oh, Sofía Romero Montepaone, Dana Tarkowská, Eugenio G. Minguet, Jonas Schön, Mariano García Hourquet, Timo Flugel, Miguel A. Blázquez, Giltsu Choi, Miroslav Strnad, Santiago Mora-García, David Alabadi, Matias D. Zurbriggen, Jorge J. Casal
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Neural crest mechanosensors: Seeing old proteins in a new light Dev. Cell (IF 13.417) Pub Date : 2022-07-27 Brenda Canales Coutiño, Roberto Mayor
Mechanical forces exerted on neural crest cells control their collective migration and differentiation. This perspective discusses our current understanding of neural crest mechanotransduction during cell migration and differentiation. Additionally, we describe proteins that have mechanosensitive functions in other systems, such as mechanosensitive G-protein-coupled receptors, mechanosensitive ion
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Temporally dynamic antagonism between transcription and chromatin compaction controls stochastic photoreceptor specification in flies Dev. Cell (IF 13.417) Pub Date : 2022-07-13 Lukas Voortman, Caitlin Anderson, Elizabeth Urban, Luorongxin Yuan, Sang Tran, Alexandra Neuhaus-Follini, Josh Derrick, Thomas Gregor, Robert J. Johnston
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FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma Dev. Cell (IF 13.417) Pub Date : 2022-07-13 Grace Orstad, Gabriela Fort, Timothy J. Parnell, Alex Jones, Chris Stubben, Brian Lohman, Katherine L. Gillis, Walter Orellana, Rushmeen Tariq, Olaf Klingbeil, Klaus Kaestner, Christopher R. Vakoc, Benjamin T. Spike, Eric L. Snyder
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It takes a lot of nerve to form the lung alveolus Dev. Cell (IF 13.417) Pub Date : 2022-07-11 Kazushige Shiraishi, Edward E. Morrisey
Autonomic nerves innervate the lungs, but how these nerves guide lung development remains unclear. In this issue of Developmental Cell, Zhang et al. reveal that myofibroblasts and developing nerves cross-communicate through neurotrophins and neurotransmitters to drive alveologenesi—and that planar cell polarity signaling is critical to this process.
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May the force be with you: Mechanosensitivity shapes dendrite development Dev. Cell (IF 13.417) Pub Date : 2022-07-11 Chun-Liang Pan
Mechanical stimuli have profound effects on the structure and function of various cells and tissues. In this issue of Developmental Cell, Tao et al. report that mechanosensory ion channels mediate the effects of cell membrane guidance cues on the morphogenesis of neuronal dendrites.
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When the anchor’s away, meiotic telomeres go astray Dev. Cell (IF 13.417) Pub Date : 2022-07-11 Ivan Olaya, Sean M. Burgess
During meiosis, microtubules emanate from the centrosome to cluster telomeres in the bouquet configuration and facilitate chromosome pairing. In a recent issue of Science, Mytlis et al. establish that a cilium in zebrafish anchors the centrosome and is important for telomere clustering and germ cell development.
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Distinct p53 isoforms code for opposing transcriptional outcomes Dev. Cell (IF 13.417) Pub Date : 2022-07-11 Annika Wylie, Amanda E. Jones, Simanti Das, Wan-Jin Lu, John M. Abrams
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Local synthesis of the phosphatidylinositol-3,4-bisphosphate lipid drives focal adhesion turnover Dev. Cell (IF 13.417) Pub Date : 2022-07-08 York Posor, Charis Kampyli, Benoit Bilanges, Sushila Ganguli, Philipp A. Koch, Alexander Wallroth, Daniele Morelli, Michalina Jenkins, Samira Alliouachene, Elitza Deltcheva, Buzz Baum, Volker Haucke, Bart Vanhaesebroeck
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Sulfenylation of ENOLASE2 facilitates H2O2-conferred freezing tolerance in Arabidopsis Dev. Cell (IF 13.417) Pub Date : 2022-07-08 Wen-Cheng Liu, Ru-Feng Song, Yi-Min Qiu, Si-Qiu Zheng, Ting-Ting Li, Yan Wu, Chun-Peng Song, Ying-Tang Lu, Hong-Mei Yuan
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A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase Dev. Cell (IF 13.417) Pub Date : 2022-07-08 Dilyana Georgieva Kirova, Kristyna Judasova, Julia Vorhauser, Thomas Zerjatke, Jacky Kieran Leung, Ingmar Glauche, Jörg Mansfeld
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Genetic variation associated with condensate dysregulation in disease Dev. Cell (IF 13.417) Pub Date : 2022-07-08 Salman F. Banani, Lena K. Afeyan, Susana W. Hawken, Jonathan E. Henninger, Alessandra Dall’Agnese, Victoria E. Clark, Jesse M. Platt, Ozgur Oksuz, Nancy M. Hannett, Ido Sagi, Tong Ihn Lee, Richard A. Young
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Neurexin and frizzled intercept axonal transport at microtubule minus ends to control synapse formation Dev. Cell (IF 13.417) Pub Date : 2022-07-08 Santiago Balseiro-Gómez, Junhyun Park, Yang Yue, Chen Ding, Lin Shao, Selim Ҫetinkaya, Caroline Kuzoian, Marc Hammarlund, Kristen J. Verhey, Shaul Yogev
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Klf5 defines alveolar epithelial type 1 cell lineage commitment during lung development and regeneration Dev. Cell (IF 13.417) Pub Date : 2022-07-07 Derek C. Liberti, William A. Liberti III, Madison M. Kremp, Ian J. Penkala, Fabian L. Cardenas-Diaz, Michael P. Morley, Apoorva Babu, Su Zhou, Rafael J. Fernandez III, Edward E. Morrisey
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Interferon-γ resistance and immune evasion in glioma develop via Notch-regulated co-evolution of malignant and immune cells Dev. Cell (IF 13.417) Pub Date : 2022-07-07 Elena Parmigiani, Robert Ivanek, Chiara Rolando, Katrin Hafen, Gleb Turchinovich, Frank Michael Lehmann, Alexandra Gerber, Sime Brkic, Stephan Frank, Sara C. Meyer, Hiroaki Wakimoto, Murat Günel, Angeliki Louvi, Luigi Mariani, Daniela Finke, Georg Holländer, Gregor Hutter, Roxane Tussiwand, Claudio Giachino
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Recruitment of tetraspanin TSP-15 to epidermal wounds promotes plasma membrane repair in C. elegans Dev. Cell (IF 13.417) Pub Date : 2022-06-30 Yuanyuan Wang, Qingxian Yang, Xinan Meng, Chandra Sugiarto Wijaya, Xuecong Ren, Suhong Xu
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Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state Dev. Cell (IF 13.417) Pub Date : 2022-06-30 Yingzi Liu, Christian F. Guerrero-Juarez, Fei Xiao, Nitish Udupi Shettigar, Raul Ramos, Chen-Hsiang Kuan, Yuh-Charn Lin, Luis de Jesus Martinez Lomeli, Jung Min Park, Ji Won Oh, Ruiqi Liu, Sung-Jan Lin, Marco Tartaglia, Ruey-Bing Yang, Zhengquan Yu, Qing Nie, Ji Li, Maksim V. Plikus
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Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD Dev. Cell (IF 13.417) Pub Date : 2022-06-28 Romain Donne, Maëva Saroul-Ainama, Pierre Cordier, Adel Hammoutene, Christelle Kabore, Mira Stadler, Ivan Nemazanyy, Isabelle Galy-Fauroux, Mounia Herrag, Tobias Riedl, Marie Chansel-Da Cruz, Stefano Caruso, Stéphanie Bonnafous, Rupert Öllinger, Roland Rad, Kristian Unger, Albert Tran, Jean-Pierre Couty, Chantal Desdouets
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Keratinocytes cut corners on the cell cycle for the sake of skin barrier integrity Dev. Cell (IF 13.417) Pub Date : 2022-06-20 Renzhi Hou, Jung Eun Kim, Maksim V. Plikus
Epidermis can grow its surface by activating mitotic division in basal stem cells. In a recent issue of Nature, Chan et al. (2022) show that under high demand for new skin, differentiated epidermal cells in zebrafish divide without DNA synthesis, forming cells in the new surface with reduced and abnormal genomes.
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Brief encounters: The relationship between enhancer proximity and gene expression Dev. Cell (IF 13.417) Pub Date : 2022-06-20 Helen Ray-Jones, Mikhail Spivakov
In a recent issue of Nature, Zuin et al. (2022) integrate a transcriptional enhancer into various genomic locations surrounding a reporter gene promoter in order to determine how enhancer-promoter proximity affects gene expression. Their findings suggest a non-linear relationship, which the authors explain via a quantitative biophysical model with intriguing biological implications.
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Damage-responsive neuro-glial clusters coordinate the recruitment of dormant neural stem cells in Drosophila Dev. Cell (IF 13.417) Pub Date : 2022-06-17 Anabel R. Simões, Marta Neto, Carolina S. Alves, Mariana B. Santos, Ismael Fernández-Hernández, Henrique Veiga-Fernandes, David Brea, Irene Durá, Juan M. Encinas, Christa Rhiner
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A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange Dev. Cell (IF 13.417) Pub Date : 2022-06-16 Kuan Zhang, Erica Yao, Shao-An Wang, Ethan Chuang, Julia Wong, Liliana Minichiello, Andrew Schroeder, Walter Eckalbar, Paul J. Wolters, Pao-Tien Chuang
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BMP-gated cell-cycle progression drives anoikis during mesenchymal collective migration Dev. Cell (IF 13.417) Pub Date : 2022-06-15 Frank Macabenta, Hsuan-Te Sun, Angelike Stathopoulos
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The cellular architecture and molecular determinants of the zebrafish fusogenic synapse Dev. Cell (IF 13.417) Pub Date : 2022-06-15 Zhou Luo, Jun Shi, Pratima Pandey, Zhi-Rong Ruan, Maria Sevdali, Ye Bu, Yue Lu, Shaojun Du, Elizabeth H. Chen
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Dendrites use mechanosensitive channels to proofread ligand-mediated neurite extension during morphogenesis Dev. Cell (IF 13.417) Pub Date : 2022-06-15 Li Tao, Sean Coakley, Rebecca Shi, Kang Shen
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Fetomaternal microchimerism in tissue repair and tumor development Dev. Cell (IF 13.417) Pub Date : 2022-06-13 Egor Sedov, Jordan McCarthy, Elle Koren, Yaron Fuchs
In various placental mammals, the bidirectional exchange of cells during pregnancy can lead to the acquisition of genetically unique cells that can persist in both mother and child for decades. Over the years, it has become increasingly clear that this phenomenon, termed fetomaternal microchimerism may play key roles in a number of biological processes. In this perspective, we explore the concept of
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Macrophages trigger cardiomyocyte proliferation by increasing epicardial vegfaa expression during larval zebrafish heart regeneration Dev. Cell (IF 13.417) Pub Date : 2022-06-09 Finnius A. Bruton, Aryan Kaveh, Katherine M. Ross-Stewart, Gianfranco Matrone, Magdalena E.M. Oremek, Emmanouil G. Solomonidis, Carl S. Tucker, John J. Mullins, Christopher D. Lucas, Mairi Brittan, Jonathan M. Taylor, Adriano G. Rossi, Martin A. Denvir
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R-SPONDIN2+ mesenchymal cells form the bud tip progenitor niche during human lung development Dev. Cell (IF 13.417) Pub Date : 2022-06-08 Renee F.C. Hein, Joshua H. Wu, Emily M. Holloway, Tristan Frum, Ansley S. Conchola, Yu-Hwai Tsai, Angeline Wu, Alexis S. Fine, Alyssa J. Miller, Emmanuelle Szenker-Ravi, Kelley S. Yan, Calvin J. Kuo, Ian Glass, Bruno Reversade, Jason R. Spence
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EED is required for mouse primordial germ cell differentiation in the embryonic gonad Dev. Cell (IF 13.417) Pub Date : 2022-06-08 Matthew G. Lowe, Ming-Ren Yen, Fei-Man Hsu, Linzi Hosohama, Zhongxun Hu, Tsotne Chitiashvili, Timothy J. Hunt, Isaac Gorgy, Matthew Bernard, Sissy E. Wamaitha, Pao-Yang Chen, Amander T. Clark
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IL18 signaling causes islet β cell development and insulin secretion via different receptors on acinar and β cells Dev. Cell (IF 13.417) Pub Date : 2022-06-07 Xian Zhang, Songyuan Luo, Minjie Wang, Qin Huang, Wenqian Fang, Jie Li, Tianxiao Liu, Yuanyuan Zhang, Zhiyong Deng, Cong-Lin Liu, Shuling Guan, Julio E. Ayala, Richard A. Flavell, Rohit N. Kulkarni, Peter Libby, Junli Guo, Zhangsuo Liu, Guo-Ping Shi
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Major construction entails major demolition Dev. Cell (IF 13.417) Pub Date : 2022-06-06 Ekaterina Korotkevich, Takashi Hiiragi
Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.
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Macrophages, masters of invasion Dev. Cell (IF 13.417) Pub Date : 2022-06-06 Denise J. Montell
Macrophages are exceptionally invasive cells. In a recent article in Science, Akhmanova et al. describe a novel mechanism facilitating macrophage infiltration into a tightly packed tissue in Drosophila embryos. Ectodermal cell rounding and division enhance macrophage entry by detaching the dividing cells from the underlying extracellular matrix.
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Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism Dev. Cell (IF 13.417) Pub Date : 2022-06-06 Kalle Sipilä, Emanuel Rognoni, Johanna Jokinen, Mukul Tewary, Matteo Vietri Rudan, Salli Talvi, Ville Jokinen, Käthe M. Dahlström, Kif Liakath-Ali, Atefeh Mobasseri, Xinyi Du-Harpur, Jarmo Käpylä, Stephen L. Nutt, Tiina A. Salminen, Jyrki Heino, Fiona M. Watt
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PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine Dev. Cell (IF 13.417) Pub Date : 2022-06-03 Deguan Lv, Ryan C. Gimple, Cuiqing Zhong, Qiulian Wu, Kailin Yang, Briana C. Prager, Bhaskar Godugu, Zhixin Qiu, Linjie Zhao, Guoxin Zhang, Deobrat Dixit, Derrick Lee, Jia Z. Shen, Xiqing Li, Qi Xie, Xiuxing Wang, Sameer Agnihotri, Jeremy N. Rich
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γ-secretase promotes Drosophila postsynaptic development through the cleavage of a Wnt receptor Dev. Cell (IF 13.417) Pub Date : 2022-06-01 Lucas J. Restrepo, Alison T. DePew, Elizabeth R. Moese, Stephen R. Tymanskyj, Michael J. Parisi, Michael A. Aimino, Juan Carlos Duhart, Hong Fei, Timothy J. Mosca
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A cilia-independent function of BBSome mediated by DLK-MAPK signaling in C. elegans photosensation Dev. Cell (IF 13.417) Pub Date : 2022-05-31 Xinxing Zhang, Jinzhi Liu, Tong Pan, Alex Ward, Jianfeng Liu, X.Z. Shawn Xu
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A human breast atlas integrating single-cell proteomics and transcriptomics Dev. Cell (IF 13.417) Pub Date : 2022-05-25 G. Kenneth Gray, Carman Man-Chung Li, Jennifer M. Rosenbluth, Laura M. Selfors, Nomeda Girnius, Jia-Ren Lin, Ron C.J. Schackmann, Walter L. Goh, Kaitlin Moore, Hana K. Shapiro, Shaolin Mei, Kurt D’Andrea, Katherine L. Nathanson, Peter K. Sorger, Sandro Santagata, Aviv Regev, Judy E. Garber, Deborah A. Dillon, Joan S. Brugge
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New adventures in spatial transcriptomics Dev. Cell (IF 13.417) Pub Date : 2022-05-23 Maayan Pour, Itai Yanai
Complex dynamic processes such as development involve the deployment of gene regulatory pathways that transform the spatial arrangement of cells. Disentangling these genetic programs is at the core of many biological problems. Stereo-seq is a promising spatial transcriptomics method, as demonstrated by three papers in this issue of Developmental Cell, each in a distinct biological context.
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Guidance by followers ensures long-range coordination of cell migration through α-catenin mechanoperception Dev. Cell (IF 13.417) Pub Date : 2022-05-24 Arthur Boutillon, Sophie Escot, Amélie Elouin, Diego Jahn, Sebastián González-Tirado, Jörn Starruß, Lutz Brusch, Nicolas B. David
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Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging Dev. Cell (IF 13.417) Pub Date : 2022-05-24 Zunpeng Liu, Qianzhao Ji, Jie Ren, Pengze Yan, Zeming Wu, Si Wang, Liang Sun, Zehua Wang, Jiaming Li, Guoqiang Sun, Chuqian Liang, Run Sun, Xiaoyu Jiang, Jianli Hu, Yingjie Ding, Qiaoran Wang, Shijia Bi, Gang Wei, Guang-Hui Liu
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The ER ladder is a unique morphological feature of developing mammalian axons Dev. Cell (IF 13.417) Pub Date : 2022-05-23 Emiliano Zamponi, Janet B. Meehl, Gia K. Voeltz
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DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism Dev. Cell (IF 13.417) Pub Date : 2022-05-20 Barbara Pernaute, Salvador Pérez-Montero, Juan Miguel Sánchez Nieto, Aida Di Gregorio, Ana Lima, Katerina Lawlor, Sarah Bowling, Gianmaria Liccardi, Alejandra Tomás, Pascal Meier, Hiromi Sesaki, Guy A. Rutter, Ivana Barbaric, Tristan A. Rodríguez
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KCNJ8/ABCC9-containing K-ATP channel modulates brain vascular smooth muscle development and neurovascular coupling Dev. Cell (IF 13.417) Pub Date : 2022-05-18 Koji Ando, Lei Tong, Di Peng, Elisa Vázquez-Liébanas, Hirohisa Chiyoda, Liqun He, Jianping Liu, Koichi Kawakami, Naoki Mochizuki, Shigetomo Fukuhara, Jaime Grutzendler, Christer Betsholtz
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Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis Dev. Cell (IF 13.417) Pub Date : 2022-05-16 Roxana E. Oberkersch, Giovanna Pontarin, Matteo Astone, Marianna Spizzotin, Liaisan Arslanbaeva, Giovanni Tosi, Emiliano Panieri, Sara Ricciardi, Maria Francesca Allega, Alessia Brossa, Paolo Grumati, Benedetta Bussolati, Stefano Biffo, Saverio Tardito, Massimo M. Santoro
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Epithelial cells adapt to curvature induction via transient active osmotic swelling Dev. Cell (IF 13.417) Pub Date : 2022-05-13 Caterina Tomba, Valeriy Luchnikov, Luca Barberi, Carles Blanch-Mercader, Aurélien Roux
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Can’t smell the virus: SARS-CoV-2, chromatin organization, and anosmia Dev. Cell (IF 13.417) Pub Date : 2022-05-09 Matan Sorek, Eran Meshorer
Anosmia, or loss of smell, is strongly associated with SARS-CoV-2 infection in humans, but the underlying mechanism remains obscure. In a recent Cell study, Zazhytska et al. (2022) report non-cell-autonomous disruption of long-range genomic interactions of olfactory receptor genes in response to SARS-CoV-2 infection, and these interactions remain disrupted long after virus clearance.
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Developmental landscape of human forebrain at a single-cell level identifies early waves of oligodendrogenesis Dev. Cell (IF 13.417) Pub Date : 2022-05-05 David van Bruggen, Fabio Pohl, Christoffer Mattsson Langseth, Petra Kukanja, Hower Lee, Alejandro Mossi Albiach, Mukund Kabbe, Mandy Meijer, Sten Linnarsson, Markus M. Hilscher, Mats Nilsson, Erik Sundström, Gonçalo Castelo-Branco
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High-resolution 3D spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae Dev. Cell (IF 13.417) Pub Date : 2022-05-04 Mingyue Wang, Qinan Hu, Tianhang Lv, Yuhang Wang, Qing Lan, Rong Xiang, Zhencheng Tu, Yanrong Wei, Kai Han, Chang Shi, Junfu Guo, Chao Liu, Tao Yang, Wensi Du, Yanru An, Mengnan Cheng, Jiangshan Xu, Haorong Lu, Longqi Liu
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The single-cell stereo-seq reveals region-specific cell subtypes and transcriptome profiling in Arabidopsis leaves Dev. Cell (IF 13.417) Pub Date : 2022-05-04 Keke Xia, Hai-Xi Sun, Jie Li, Jiming Li, Yu Zhao, Lichuan Chen, Chao Qin, Ruiying Chen, Zhiyong Chen, Guangyu Liu, Ruilian Yin, Bangbang Mu, Xiaojuan Wang, Mengyuan Xu, Xinyue Li, Peisi Yuan, Yixin Qiao, Shijie Hao, Xun Xu
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Spatiotemporal mapping of gene expression landscapes and developmental trajectories during zebrafish embryogenesis Dev. Cell (IF 13.417) Pub Date : 2022-05-04 Chang Liu, Rui Li, Young Li, Xiumei Lin, Kaichen Zhao, Qun Liu, Shuowen Wang, Xueqian Yang, Xuyang Shi, Yuting Ma, Chenyu Pei, Hui Wang, Wendai Bao, Junhou Hui, Tao Yang, Zhicheng Xu, Tingting Lai, Michael Arman Berberoglu, Longqi Liu
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ISL2 is a putative tumor suppressor whose epigenetic silencing reprograms the metabolism of pancreatic cancer Dev. Cell (IF 13.417) Pub Date : 2022-05-03 Harun Ozturk, Harun Cingoz, Turan Tufan, Jiekun Yang, Sara J. Adair, Krishna Seshu Tummala, Cem Kuscu, Meric Kinali, Gamze Comertpay, Sarbajeet Nagdas, Bernadette J. Goudreau, Husnu Umit Luleyap, Yagmur Bingul, Timothy B. Ware, Wiliam L. Hwang, Ku-lung Hsu, David F. Kashatus, David T. Ting, Mazhar Adli