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Targeting an alternative route: autophagy in RAS-driven cancers Cell Res. (IF 28.1) Pub Date : 2025-05-16 Alina Üffing, Eleanor Attridge, Sharon A. Tooze
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Mucin-like protein of Crimean-Congo hemorrhagic fever virus is a key virulence factor and a potent target for developing novel attenuated vaccine Cell Res. (IF 28.1) Pub Date : 2025-05-16 Liushuai Li, Yajie Liu, Juhong Rao, Hengrui Hu, Jia Liu, Xi Wang, Jiang Li, Zhihong Hu, Manli Wang
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A thermosensor FUST1 primes heat-induced stress granule formation via biomolecular condensation in Arabidopsis Cell Res. (IF 28.1) Pub Date : 2025-05-14 Pan Geng, Changxuan Li, Xuebo Quan, Jiaxuan Peng, Zhiying Yao, Yunhe Wang, Ming Yang, Yanning Wang, Yunfan Jin, Yan Xiong, Hongtao Liu, Yijun Qi, Peiguo Yang, Kai Huang, Xiaofeng Fang
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DNA remnants in red blood cells enable early detection of cancer Cell Res. (IF 28.1) Pub Date : 2025-05-09 Haobo Sun, Xingyun Yao, Yurong Jiao, Xiangxing Kong, Yuehua Han, Ying Li, Jianping Ge, Yanfei Cao, Hongsheng Lu, Pingli Wang, Yu Xu, Jun Li, Kefeng Ding, Xiaofei Gao
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Allogeneic anti-CD19 CAR-T cells induce remission in refractory systemic lupus erythematosus Cell Res. (IF 28.1) Pub Date : 2025-05-08 Chunmei Yang, Chuanyin Sun, Binghe Tan, Chao Hu, Liyan Wan, Chris Wang, Xiujuan Shi, Juliang Qin, Na Zhang, Biao Zheng, Mingyao Liu, Jin Lin, Bing Du, Hongyan Tong
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Lysosomal EGFR functions as a GEF for Rheb Cell Res. (IF 28.1) Pub Date : 2025-05-07 Tao Hou, Peiqiang Yan, Hiroyuki Inuzuka, Wenyi Wei
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Author Correction: Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity Cell Res. (IF 28.1) Pub Date : 2025-05-07 Ling-Qi Xie, Biao Hu, Ren-Bin Lu, Ya-Lun Cheng, Xin Chen, Jie Wen, Yao Xiao, Yu-Ze An, Ning Peng, Yu Dai, Genqing Xie, Qi Guo, Hui Peng, Xiang-Hang Luo
Correction to: Cell Research https://doi.org/10.1038/s41422-025-01078-8, published online 29 January 2025
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Neural crossroads of pancreatic cancer: how nociceptors drive tumor progression and immune evasion Cell Res. (IF 28.1) Pub Date : 2025-05-07 Carmen Mota Reyes, Helmut Friess, Ihsan Ekin Demir
Nociceptor neurons actively promote pancreatic ductal adenocarcinoma progression by suppressing immune responses through interactions with cancer-associated fibroblasts. Targeting their signaling pathways offers a novel strategy for enhancing anti-tumor immunity and managing cancer pain.
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Orchestrating NTSR1 signaling from the interface Cell Res. (IF 28.1) Pub Date : 2025-04-21 Xianglin Huang, Brian E. Krumm, Bryan L. Roth
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Spliceosome-associated quality control Cell Res. (IF 28.1) Pub Date : 2025-04-21 Nikita Sharaev, Jiangfeng Zhao, Wojciech P. Galej
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Gasdermin D pores hitch a ride: extracellular vesicles spread pyroptosis Cell Res. (IF 28.1) Pub Date : 2025-04-21 Gang Du, Hao Wu
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Decoding NLRP3: Phase separation enters the scene Cell Res. (IF 28.1) Pub Date : 2025-04-21 Niklas A. Schmacke, Veit Hornung
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Lysosomal EGFR acts as a Rheb-GEF independent of its kinase activity to activate mTORC1 Cell Res. (IF 28.1) Pub Date : 2025-04-21 Xiaobo He, Qiu-Xia Wang, Denghui Wei, Yujie Lin, Xia Zhang, Yuanzhong Wu, Xuexia Qian, Zhihao Lin, Beibei Xiao, Qinxue Wu, Zhen Wang, Fengtao Zhou, Zhihao Wei, Jingxuan Wang, Run Gong, Ruhua Zhang, Qingling Zhang, Ke Ding, Song Gao, Tiebang Kang
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Pyrimidine synthase CAD deamidates and inactivates p53 Cell Res. (IF 28.1) Pub Date : 2025-04-17 Yue Qi, Zizheng Tan, Hanyu Chen, Ziqi Xiao, Liang Zhang, Boxuan Wu, Chennan Liu, Yunqian Gao, Xueyan Yang, Lingqian Wu, Lei Lu, Hongyan Wang
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Author Correction: Structural and functional evidence that GPR30 is not a direct estrogen receptor Cell Res. (IF 28.1) Pub Date : 2025-04-16 Heng Liu, Shimeng Guo, Antao Dai, Peiyu Xu, Xin Li, Sijie Huang, Xinheng He, Kai Wu, Xinyue Zhang, Dehua Yang, Xin Xie, H. Eric Xu
Correction to: Cell Research https://doi.org/10.1038/s41422-024-00963-y, published online 14 May 2024
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Mechanistic insights into RNA cleavage by human Argonaute2–siRNA complex Cell Res. (IF 28.1) Pub Date : 2025-04-16 Zhenzhen Li, Qikui Xu, Yan Zhang, Jing Zhong, Tianxiang Zhang, Junchao Xue, Shuxian Liu, Haishan Gao, Z. Z. Zhao Zhang, Jianping Wu, En-Zhi Shen
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Why resident microglial-like cells were missed in the peripheral nervous system Cell Res. (IF 28.1) Pub Date : 2025-04-15 Michal Schwartz
In a recent paper in Cell, Wu et al. described a novel peripheral nervous system (PNS) resident myeloid cell population, which the authors named microglia-like PNS cells.
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Selective CDK4 inhibition holds promise for breast cancer Cell Res. (IF 28.1) Pub Date : 2025-04-14 Manuel Beltrán-Visiedo, Rebecca M. Shulman, Lorenzo Galluzzi
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Beyond peptide targeting sequences: machine learning of cellular condensate localization Cell Res. (IF 28.1) Pub Date : 2025-04-14 Jonathon A. Ditlev, Julie D. Forman-Kay
Proteins within cells must navigate complex intracellular environments to co-localize with partners and regulate functional cellular organization. In a recentScience paper, Kilgore et al. report the development of ProtGPS, a machine learning-trained predictor of protein localization within biomolecular condensates in cells that can be used to predict the ability of disease-linked mutations to dysregulate
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Phase separation paints Xi with Xist Cell Res. (IF 28.1) Pub Date : 2025-04-14 Thomas C. T. Michaels, Anton Wutz
In a recent study, Ding et al. investigated the role of hnRNPK phase separation in mammalian dosage compensation. The study stands out by linking biophysical and biochemical measurements with genetic and cell biological experimentation, providing wide-ranging evidence for specific mechanistic aspects of X chromosome inactivation, while expanding the potential repertoire for phase separation in biology
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Structural basis of stepwise proton sensing-mediated GPCR activation Cell Res. (IF 28.1) Pub Date : 2025-04-11 Xiaolei Yue, Li Peng, Shenhui Liu, Bingjie Zhang, Xiaodan Zhang, Hao Chang, Yuan Pei, Xiaoting Li, Junlin Liu, Wenqing Shui, Lijie Wu, Huji Xu, Zhi-Jie Liu, Tian Hua
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Mechanisms of chromatin remodeling by the human Snf2-type ATPase SNF2H Cell Res. (IF 28.1) Pub Date : 2025-04-03 Deepshikha Malik, Ashish Deshmukh, Silvija Bilokapic, Mario Halic
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Pyroptosis: molecular mechanisms and roles in disease Cell Res. (IF 28.1) Pub Date : 2025-04-03 Petr Broz
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Signal-induced NLRP3 phase separation initiates inflammasome activation Cell Res. (IF 28.1) Pub Date : 2025-04-01 Gonglu Zou, Yuluan Tang, Jie Yang, Shuo Fu, Yuheng Li, Xuanyao Ren, Nanhai Zhou, Wenlong Zhao, Juyi Gao, Ziran Ruan, Zhengfan Jiang
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A phytoalexin dismantles bacterial type III injectisome Cell Res. (IF 28.1) Pub Date : 2025-03-31 Manman Zhang, Cheng Li, Zheng Qing Fu
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Author Correction: Improved survival of porcine acute liver failure by a bioartificial liver device implanted with induced human functional hepatocytes Cell Res. (IF 28.1) Pub Date : 2025-03-27 Xiao-Lei Shi, Yimeng Gao, Yupeng Yan, Hucheng Ma, Lulu Sun, Pengyu Huang, Xuan Ni, Ludi Zhang, Xin Zhao, Haozhen Ren, Dan Hu, Yan Zhou, Feng Tian, Yuan Ji, Xin Cheng, Guoyu Pan, Yi-Tao Ding, Lijian Hui
Correction to: Cell Research https://doi.org/10.1038/cr.2016.6, published online 15 January 2016
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Identification of a GPCR as a tip link-independent equilibrioceptor Cell Res. (IF 28.1) Pub Date : 2025-03-25 Biyun Zhu, Shao Wei Hu, Yilai Shu
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Mechano-pharmacology of T cell receptor specificity Cell Res. (IF 28.1) Pub Date : 2025-03-25 Panyu Fei, Michael L. Dustin
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The night shift: norepinephrine drives glymphatics Cell Res. (IF 28.1) Pub Date : 2025-03-25 Benjamin A. Plog, Leon C. D. Smyth, Jonathan Kipnis
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Broad H3K4me3 domains orchestrate temporal control of gene expression Cell Res. (IF 28.1) Pub Date : 2025-03-25 Yuka Kitamura, Mengwen Hu, Satoshi H. Namekawa
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Grow AI virtual cells: three data pillars and closed-loop learning Cell Res. (IF 28.1) Pub Date : 2025-03-25 Liujia Qian, Zhen Dong, Tiannan Guo
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Nociceptor neurons promote PDAC progression and cancer pain by interaction with cancer-associated fibroblasts and suppression of natural killer cells Cell Res. (IF 28.1) Pub Date : 2025-03-24 Kaiyuan Wang, Bo Ni, Yongjie Xie, Zekun Li, Limei Yuan, Chenyang Meng, Tiansuo Zhao, Song Gao, Chongbiao Huang, Hongwei Wang, Ying Ma, Tianxing Zhou, Yukuan Feng, Antao Chang, Chao Yang, Jun Yu, Wenwen Yu, Fenglin Zang, Yanhui Zhang, Ru-Rong Ji, Xiuchao Wang, Jihui Hao
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Target DNA-induced filament formation and nuclease activation of SPARDA complex Cell Res. (IF 28.1) Pub Date : 2025-03-24 Feng Wang, Haijiang Xu, Chendi Zhang, Jialin Xue, Zhuang Li
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Molecular mechanism of the arrestin-biased agonism of neurotensin receptor 1 by an intracellular allosteric modulator Cell Res. (IF 28.1) Pub Date : 2025-03-21 Demeng Sun, Xiang Li, Qingning Yuan, Yuanxia Wang, Pan Shi, Huanhuan Zhang, Tao Wang, Wenjing Sun, Shenglong Ling, Yuanchun Liu, Jinglin Lai, Wenqin Xie, Wanchao Yin, Lei Liu, H. Eric Xu, Changlin Tian
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Structural basis of augmenting taurine uptake by the taurine transporter in alleviating cellular senescence Cell Res. (IF 28.1) Pub Date : 2025-03-20 Heng Zhang, Nana Cui, Xiong Ma, H. Eric Xu
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Author Correction: LKB1 inactivation promotes epigenetic remodeling-induced lineage plasticity and antiandrogen resistance in prostate cancer Cell Res. (IF 28.1) Pub Date : 2025-03-18 Fei Li, Pengfei Dai, Huili Shi, Yajuan Zhang, Juan He, Anuradha Gopalan, Dan Li, Yu Chen, Yarui Du, Guoliang Xu, Weiwei Yang, Chao Liang, Dong Gao
Correction to: Cell Research https://doi.org/10.1038/s41422-024-01025-z, published online 02 January 2025
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New insights into how parental worms protect their offspring Cell Res. (IF 28.1) Pub Date : 2025-03-14 Chenming Zeng, Eric A. Miska
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Killing cancer quickly: inducing hyper-acute rejection of patient tumors Cell Res. (IF 28.1) Pub Date : 2025-03-13 Eric Bartee
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Publisher Correction: Comprehensive discovery and functional characterization of the noncanonical proteome Cell Res. (IF 28.1) Pub Date : 2025-03-10 Chengyu Shi, Fangzhou Liu, Xinwan Su, Zuozhen Yang, Ying Wang, Shanshan Xie, Shaofang Xie, Qiang Sun, Yu Chen, Lingjie Sang, Manman Tan, Linyu Zhu, Kai Lei, Junhong Li, Jiecheng Yang, Zerui Gao, Meng Yu, Xinyi Wang, Junfeng Wang, Jing Chen, Wei Zhuo, Zhaoyuan Fang, Jian Liu, Qingfeng Yan, Dante Neculai, Qiming Sun, Jianzhong Shao, Weiqiang Lin, Wei Liu, Jian Chen, Liangjing Wang, Yang Liu, Xu Li, Tianhua
Correction to: Cell Research https://doi.org/10.1038/s41422-024-01059-3, published online 10 January 2025
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Oncogenic RAS induces a distinctive form of non-canonical autophagy mediated by the P38-ULK1-PI4KB axis Cell Res. (IF 28.1) Pub Date : 2025-03-07 Xiaojuan Wang, Shulin Li, Shiyin Lin, Yaping Han, Tong Zhan, Zhiying Huang, Juanjuan Wang, Ying Li, Haiteng Deng, Min Zhang, Du Feng, Liang Ge
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SETD1B-mediated broad H3K4me3 controls proper temporal patterns of gene expression critical for spermatid development Cell Res. (IF 28.1) Pub Date : 2025-03-04 Zhen Lin, Bowen Rong, Ruitu Lyu, Yuxuan Zheng, Yao Chen, Junyi Yan, Meixia Wu, Xiaogang Gao, Fuchou Tang, Fei Lan, Ming-Han Tong
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NO-immune privilege for hematopoietic stem cells Cell Res. (IF 28.1) Pub Date : 2025-02-28 Agathe L. Chédeville, Simón Méndez-Ferrer
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Structural basis of phosphate export by human XPR1 Cell Res. (IF 28.1) Pub Date : 2025-02-28 Yifei Wang, Yuechan Wang, Hui Yang, Ao Li, Dan Ma, Huaizong Shen
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Structural insights into spliceosome fidelity: DHX35–GPATCH1- mediated rejection of aberrant splicing substrates Cell Res. (IF 28.1) Pub Date : 2025-02-28 Yi Li, Paulina Fischer, Mengjiao Wang, Qianxing Zhou, Aixia Song, Rui Yuan, Wanyu Meng, Fei Xavier Chen, Reinhard Lührmann, Benjamin Lau, Ed Hurt, Jingdong Cheng
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TCR catch bonds nonlinearly control CD8 cooperation to shape T cell specificity Cell Res. (IF 28.1) Pub Date : 2025-02-27 Rui Qin, Yong Zhang, Jiawei Shi, Peng Wu, Chenyi An, Zhenhai Li, Nuo Liu, Ziyan Wan, Ting Hua, Xiaolong Li, Jizhong Lou, Weiwei Yin, Wei Chen
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Author Correction: The rapid proximity labeling system PhastID identifies ATP6AP1 as an unconventional GEF for Rheb Cell Res. (IF 28.1) Pub Date : 2025-02-28 Ran Feng, Feng Liu, Ruofei Li, Zhifen Zhou, Zhuoheng Lin, Song Lin, Shengcheng Deng, Yingying Li, Baoting Nong, Ying Xia, Zhiyi Li, Xiaoqin Zhong, Shuhan Yang, Gang Wan, Wenbin Ma, Su Wu, Zhou Songyang
Correction to: Cell Research https://doi.org/10.1038/s41422-024-00938-z, published online 06 March 2024
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Mimicking the TCR immune synapse for improved CAR-T cell function Cell Res. (IF 28.1) Pub Date : 2025-02-25 Tom Enbar, Li Tang
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Grease, fuel and target — polyunsaturated lipids in metastasis Cell Res. (IF 28.1) Pub Date : 2025-02-25 Annemarie Schwab, Thomas Brabletz
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Hangry hairs: intermittent fasting linked to hair loss Cell Res. (IF 28.1) Pub Date : 2025-02-25 Carlos Galvan, William E. Lowry
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A force-sensitive adhesion GPCR is required for equilibrioception Cell Res. (IF 28.1) Pub Date : 2025-02-18 Zhao Yang, Shu-Hua Zhou, Qi-Yue Zhang, Zhi-Chen Song, Wen-Wen Liu, Yu Sun, Ming-Wei Wang, Xiao-Long Fu, Kong-Kai Zhu, Ying Guan, Jie-Yu Qi, Xiao-Hui Wang, Yu-Nan Sun, Yan Lu, Yu-Qi Ping, Yue-Tong Xi, Zhen-Xiao Teng, Lei Xu, Peng Xiao, Zhi-Gang Xu, Wei Xiong, Wei Qin, Wei Yang, Fan Yi, Ren-Jie Chai, Xiao Yu, Jin-Peng Sun
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Raptin, a novel brain hormone links sleep health to body weight gain Cell Res. (IF 28.1) Pub Date : 2025-02-17 Leonie Cabot, Henning Fenselau
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Halt aging? — functional HSCs lead the way Cell Res. (IF 28.1) Pub Date : 2025-02-06 Rebecca T. Chu, Adam B. Schroer, Saul A. Villeda
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Raptin, a sleep-induced hypothalamic hormone, suppresses appetite and obesity Cell Res. (IF 28.1) Pub Date : 2025-01-29 Ling-Qi Xie, Biao Hu, Ren-Bin Lu, Ya-Lun Cheng, Xin Chen, Jie Wen, Yao Xiao, Yu-Ze An, Ning Peng, Yu Dai, Genqing Xie, Qi Guo, Hui Peng, Xiang-Hang Luo
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Author Correction: Heat acclimation in mice requires preoptic BDNF neurons and postsynaptic potentiation Cell Res. (IF 28.1) Pub Date : 2025-01-24 Baoting Chen, Cuicui Gao, Changhao Liu, Tongtong Guo, Junwei Hu, Jialiang Xue, Kangmin Tang, Yuelai Chen, Tian Yu, Qiwei Shen, Hongbin Sun, Wen Z. Yang, Wei L. Shen
Correction to: Cell Research https://doi.org/10.1038/s41422-024-01064-6, published online 26 December 2024
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Transport and inhibition mechanism for human TauT-mediated taurine uptake Cell Res. (IF 28.1) Pub Date : 2025-01-21 Yulin Chao, Zixuan Zhou, Hao Xia, Chuanhui Yang, Tingting Li, Yi-Quan Tang, Yilai Shu, Qian Ba, Jiaxu Hong, Dianfan Li, Qianhui Qu
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H₂O₂ regulates rice defense via bHLH25 oxidation Cell Res. (IF 28.1) Pub Date : 2025-01-20 Lijun Cao, Xinnian Dong
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Beyond housekeeping: a new role of snoRNA in nascent protein secretion Cell Res. (IF 28.1) Pub Date : 2025-01-20 Hao Wu, Chu-Xiao Liu, Ling-Ling Chen
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Metabolite is a part of immune-regulating circuit Cell Res. (IF 28.1) Pub Date : 2025-01-17 Han Wang, Shi-Min Zhao
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Chemogenetics for sensing antigens Cell Res. (IF 28.1) Pub Date : 2025-01-15 Blake A. Fordyce, Bryan L. Roth