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OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer Cell Death Differ. (IF 8.086) Pub Date : 2020-03-30 Rune Busk Damgaard; Helen E. Jolin; Michael E. D. Allison; Susan E. Davies; Hannah L. Titheradge; Andrew N. J. McKenzie; David Komander
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HPV-mediated nuclear export of HP1γ drives cervical tumorigenesis by downregulation of p53 Cell Death Differ. (IF 8.086) Pub Date : 2020-03-23 Sang Ah Yi; Dong Hoon Lee; Go Woon Kim; Hyun-Wook Ryu; Jong Woo Park; Jaecheol Lee; Jihoon Han; Jee Hun Park; Hwamok Oh; Jieun Lee; Junjeong Choi; Hyun-Soo Kim; Hyeok Gu Kang; Da-Hyun Kim; Kyung-Hee Chun; Jueng Soo You; Jeung-Whan Han; So Hee Kwon
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Correction: Cumulative inactivation of Nell-1 in Wnt1 expressing cell lineages results in craniofacial skeletal hypoplasia and postnatal hydrocephalus Cell Death Differ. (IF 8.086) Pub Date : 2020-03-23 Xiaoyan Chen; Huiming Wang; Mengliu Yu; Jong Kil Kim; Huichuan Qi; Pin Ha; Wenlu Jiang; Eric Chen; Xiangyou Luo; Ryan Brent Needle; Lloyd Baik; Cathryn Yang; Jiejun Shi; Jin Hee Kwak; Kang Ting; Xinli Zhang; Chia Soo
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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COVID-19 infection: the perspectives on immune responses Cell Death Differ. (IF 8.086) Pub Date : 2020-03-23 Yufang Shi; Ying Wang; Changshun Shao; Jianan Huang; Jianhe Gan; Xiaoping Huang; Enrico Bucci; Mauro Piacentini; Giuseppe Ippolito; Gerry Melino
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Drp1 modulates mitochondrial stress responses to mitotic arrest Cell Death Differ. (IF 8.086) Pub Date : 2020-03-19 Aida Peña-Blanco; Manuel D. Haschka; Andreas Jenner; Theresia Zuleger; Tassula Proikas-Cezanne; Andreas Villunger; Ana J. García-Sáez
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Inhibitor of apoptosis-stimulating protein of p53 inhibits ferroptosis and alleviates intestinal ischemia/reperfusion-induced acute lung injury Cell Death Differ. (IF 8.086) Pub Date : 2020-03-18 Yingchuan Li; Yongmei Cao; Jian Xiao; Jiawei Shang; Qin Tan; Feng Ping; Weifeng Huang; Fang Wu; Haijun Zhang; Xiaoping Zhang
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RIPK3 collaborates with GSDMD to drive tissue injury in lethal polymicrobial sepsis Cell Death Differ. (IF 8.086) Pub Date : 2020-03-09 Hui Chen; Yinshuang Li; Jianfeng Wu; Guoping Li; Xuan Tao; Kunmei Lai; Ying Yuan; Xiaohong Zhang; Zhenhuan Zou; Yanfang Xu
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Angiotensin-(1–9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway Cell Death Differ. (IF 8.086) Pub Date : 2020-03-09 Cristian Sotomayor-Flores; Pablo Rivera-Mejías; César Vásquez-Trincado; Camila López-Crisosto; Pablo E. Morales; Christian Pennanen; Iva Polakovicova; Víctor Aliaga-Tobar; Lorena García; Juan Carlos Roa; Beverly A. Rothermel; Vinicius Maracaja-Coutinho; Hung Ho-Xuan; Gunter Meister; Mario Chiong; María Paz Ocaranza; Alejandro H. Corvalán; Valentina Parra; Sergio Lavandero
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Correction: Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload Cell Death Differ. (IF 8.086) Pub Date : 2020-03-09 Nicoletta Plotegher; Dany Perocheau; Ruggero Ferrazza; Giulia Massaro; Gauri Bhosale; Federico Zambon; Ahad A. Rahim; Graziano Guella; Simon N. Waddington; Gyorgy Szabadkai; Michael R. Duchen
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Fenretinide induces a new form of dynamin-dependent cell death in pediatric sarcoma Cell Death Differ. (IF 8.086) Pub Date : 2020-03-06 Eva Brack; Marco Wachtel; Anja Wolf; Andres Kaech; Urs Ziegler; Beat W. Schäfer
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The lipogenic LXR-SREBF1 signaling pathway controls cancer cell DNA repair and apoptosis and is a vulnerable point of malignant tumors for cancer therapy Cell Death Differ. (IF 8.086) Pub Date : 2020-03-06 Bo Yang; Bin Zhang; Zhifei Cao; Xingdong Xu; Zihe Huo; Pan Zhang; Shufen Xiang; Zhe Zhao; Chunping Lv; Mei Meng; Gaochuan Zhang; Liang Dong; Shucheng Shi; Lan Yang; Quansheng Zhou
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BRUCE preserves genomic stability in the male germline of mice Cell Death Differ. (IF 8.086) Pub Date : 2020-03-05 Lixiao Che; Kris G. Alavattam; Peter J. Stambrook; Satoshi H. Namekawa; Chunying Du
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Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling Cell Death Differ. (IF 8.086) Pub Date : 2020-03-05 Naijin Zhang; Ying Zhang; Hao Qian; Shaojun Wu; Liu Cao; Yingxian Sun
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53BP1 loss rescues embryonic lethality but not genomic instability of BRCA1 total knockout mice Cell Death Differ. (IF 8.086) Pub Date : 2020-03-05 Jiyuan Chen; Peng Li; Licun Song; Long Bai; Michael S. Y. Huen; Yidan Liu; Lin-Yu Lu
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Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15. Cell Death Differ. (IF 8.086) Pub Date : 2020-03-03 EunBin Kong,Hag Dong Kim,Joon Kim
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Oocyte competence is maintained by m 6 A methyltransferase KIAA1429-mediated RNA metabolism during mouse follicular development Cell Death Differ. (IF 8.086) Pub Date : 2020-02-24 Yue Hu; Zhangyi Ouyang; Xuesong Sui; Meijie Qi; Mingrui Li; Yuanlin He; Yumeng Cao; Qiqi Cao; Qianneng Lu; Shuai Zhou; Lu Liu; Li Liu; Bin Shen; Wenjie Shu; Ran Huo
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MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex Cell Death Differ. (IF 8.086) Pub Date : 2020-02-24 Tirta Mario Djajawi; Lei Liu; Jia-nan Gong; Allan Shuai Huang; Ming-jie Luo; Zhen Xu; Toru Okamoto; Melissa J. Call; David C. S. Huang; Mark F. van Delft
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Convergence of pathway analysis and pattern recognition predicts sensitization to latest generation TRAIL therapeutics by IAP antagonism. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-21 Vesna Vetma,Cristiano Guttà,Nathalie Peters,Christian Praetorius,Meike Hutt,Oliver Seifert,Friedegund Meier,Roland Kontermann,Dagmar Kulms,Markus Rehm
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Squamous differentiation requires G2/mitosis slippage to avoid apoptosis. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-20 Natalia Sanz-Gómez,Isabel de Pedro,Beatriz Ortigosa,David Santamaría,Marcos Malumbres,Guillermo de Cárcer,Alberto Gandarillas
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Rab5a activates IRS1 to coordinate IGF-AKT-mTOR signaling and myoblast differentiation during muscle regeneration. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-12 Xiao Xia Cong,Xiu Kui Gao,Xi Sheng Rao,Jie Wen,Xiao Ceng Liu,Yin Pu Shi,Min Yi He,Wei Liang Shen,Yue Shen,Hongwei Ouyang,Ping Hu,Boon Chuan Low,Zhuo Xian Meng,Yue Hai Ke,Ming Zhu Zheng,Lin Rong Lu,Yong Heng Liang,Li Ling Zheng,Yi Ting Zhou
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Drp1 overexpression induces desmin disassembling and drives kinesin-1 activation promoting mitochondrial trafficking in skeletal muscle. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-10 Matteo Giovarelli,Silvia Zecchini,Emanuele Martini,Massimiliano Garrè,Sara Barozzi,Michela Ripolone,Laura Napoli,Marco Coazzoli,Chiara Vantaggiato,Paulina Roux-Biejat,Davide Cervia,Claudia Moscheni,Cristiana Perrotta,Dario Parazzoli,Emilio Clementi,Clara De Palma
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Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-10 Serena Mancarella,Grazia Serino,Francesco Dituri,Antonio Cigliano,Silvia Ribback,Jingxiao Wang,Xin Chen,Diego F Calvisi,Gianluigi Giannelli
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Spatio-temporal characterization of the antiviral activity of the XRN1-DCP1/2 aggregation against cytoplasmic RNA viruses to prevent cell death. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-07 Chen Seng Ng,Dacquin M Kasumba,Takashi Fujita,Honglin Luo
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Mutant GTF2I induces cell transformation and metabolic alterations in thymic epithelial cells. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-07 In-Kyu Kim,Guanhua Rao,Xiaoliang Zhao,Ruzong Fan,Maria Laura Avantaggiati,Yisong Wang,Yu-Wen Zhang,Giuseppe Giaccone
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Correction: Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-05 Chao Liu,Zhaoying Yao,Jianing Wang,Wen Zhang,Yan Yang,Yan Zhang,Xinliang Qu,Yubing Zhu,Jianjun Zou,Sishi Peng,Yan Zhao,Shuli Zhao,Bangshun He,Qiongyu Mi,Xiuting Liu,Xu Zhang,Qianming Du
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Correction: The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-05 Maritza Oñate,Alejandra Catenaccio,Natalia Salvadores,Cristian Saquel,Alexis Martinez,Ines Moreno-Gonzalez,Nazaret Gamez,Paulina Soto,Claudio Soto,Claudio Hetz,Felipe A Court
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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MARCH5-dependent degradation of MCL1/NOXA complexes defines susceptibility to antimitotic drug treatment. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-03 Manuel D Haschka,Gerlinde Karbon,Claudia Soratroi,Katelyn L O'Neill,Xu Luo,Andreas Villunger
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PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain. Cell Death Differ. (IF 8.086) Pub Date : 2020-02-03 Libo Su,Xuepei Lei,Hongyan Ma,Chao Feng,Jing Jiang,Jianwei Jiao
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Roles of mTORC1 and mTORC2 in controlling γδ T1 and γδ T17 differentiation and function. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-30 Quanli Yang,Xia Liu,Qihui Liu,Zerong Guan,Jing Luo,Guangchao Cao,Ruitian Cai,Zhenhua Li,Yan Xu,Zengfeng Wu,Miaomiao Xu,Song Zhang,Fan Zhang,Hengwen Yang,Xuejia Lin,Meixiang Yang,Yangzhe Wu,Yunfei Gao,Richard Flavell,Jianlei Hao,Zhinan Yin
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Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-29 Patryk Janus,Agnieszka Toma-Jonik,Natalia Vydra,Katarzyna Mrowiec,Joanna Korfanty,Marek Chadalski,Piotr Widłak,Karolina Dudek,Anna Paszek,Marek Rusin,Joanna Polańska,Wiesława Widłak
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NF-κB-p62-NRF2 survival signaling is associated with high ROR1 expression in chronic lymphocytic leukemia. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-28 Elsa Sanchez-Lopez,Emanuela M Ghia,Laura Antonucci,Natasha Sharma,Laura Z Rassenti,Jinyi Xu,Beicheng Sun,Thomas J Kipps,Michael Karin
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Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-27 Charis E Teh,Jia-Nan Gong,David Segal,Tania Tan,Cassandra J Vandenberg,Pasquale L Fedele,Michael S Y Low,George Grigoriadis,Simon J Harrison,Andreas Strasser,Andrew W Roberts,David C S Huang,Garry P Nolan,Daniel H D Gray,Melissa E Ko
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RIPK3 upregulation confers robust proliferation and collateral cystine-dependence on breast cancer recurrence. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-27 Chao-Chieh Lin,Nathaniel W Mabe,Yi-Tzu Lin,Wen-Hsuan Yang,Xiaohu Tang,Lisa Hong,Tianai Sun,Jeremy Force,Jeffrey R Marks,Tso-Pang Yao,James V Alvarez,Jen-Tsan Chi
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Autophagy in animal development Cell Death Differ. (IF 8.086) Pub Date : 2020-01-27 Elizabeth A. Allen; Eric H. Baehrecke
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Synergistic therapeutic effect of combined PDGFR and SGK1 inhibition in metastasis-initiating cells of breast cancer. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-22 Lu Yang,Ning Li,Zhicheng Xue,Ling-Rui Liu,Jian Li,Xiaojia Huang,Xinhua Xie,Yutian Zou,Hailin Tang,Xiaoming Xie
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Targeting LncDACH1 promotes cardiac repair and regeneration after myocardium infarction. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-22 Benzhi Cai,Wenya Ma,Xiuxiu Wang,Natalia Sukhareva,Bingjie Hua,Lai Zhang,Juan Xu,Xingda Li,Shuainan Li,Shenzhen Liu,Meixi Yu,Yan Xu,Ruijie Song,Binbin Xu,Fan Yang,Zhenbo Han,Fengzhi Ding,Qi Huang,Ying Yu,Yue Zhao,Jin Wang,Djibril Bamba,Naufal Zagidullin,Faqian Li,Ye Tian,Zhenwei Pan,Baofeng Yang
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TRIM proteins in autophagy: selective sensors in cell damage and innate immune responses Cell Death Differ. (IF 8.086) Pub Date : 2020-01-22 Martina Di Rienzo; Alessandra Romagnoli; Manuela Antonioli; Mauro Piacentini; Gian Maria Fimia
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NBS1 is required for SPO11-linked DNA double-strand break repair in male meiosis. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-21 Bin Zhang,Zhenghui Tang,Lejun Li,Lin-Yu Lu
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Prolyl hydroxylase 3 controls the intestine goblet cell generation through stabilizing ATOH1. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-20 Yi-Ming Xu,Qiang Gao,Jin-Zhao Zhang,Yun-Tao Lu,Dong-Ming Xing,Yan-Qing Qin,Jing Fang
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Dissecting DISC regulation via pharmacological targeting of caspase-8/c-FLIPL heterodimer. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-20 Laura K Hillert,Nikita V Ivanisenko,Denise Busse,Johannes Espe,Corinna König,Sergey E Peltek,Nikolai A Kolchanov,Vladimir A Ivanisenko,Inna N Lavrik
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Inhibition of the mitochondrial citrate carrier, Slc25a1, reverts steatosis, glucose intolerance, and inflammation in preclinical models of NAFLD/NASH. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-20 Mingjun Tan,Rami Mosaoa,Garrett T Graham,Anna Kasprzyk-Pawelec,Shreyas Gadre,Erika Parasido,Olga Catalina-Rodriguez,Patricia Foley,Giuseppe Giaccone,Amrita Cheema,Bhaskar Kallakury,Chris Albanese,Chunling Yi,Maria Laura Avantaggiati
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LINC00662 promotes hepatocellular carcinoma progression via altering genomic methylation profiles. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-20 Tao Guo,Cheng Gong,Ping Wu,Shyue-Fang Battaglia-Hsu,Juan Feng,Pengpeng Liu,Haitao Wang,Deliang Guo,Ye Yao,Baiyang Chen,Yusha Xiao,Zhisu Liu,Zhen Li
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AXL and CAV-1 play a role for MTH1 inhibitor TH1579 sensitivity in cutaneous malignant melanoma. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-09 Ishani Das,Helge Gad,Lars Bräutigam,Linda Pudelko,Rainer Tuominen,Veronica Höiom,Ingrid Almlöf,Varshni Rajagopal,Johan Hansson,Thomas Helleday,Suzanne Egyházi Brage,Ulrika Warpman Berglund
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Saga of Mcl-1: regulation from transcription to degradation. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-06 Viacheslav V Senichkin,Alena Y Streletskaia,Anna S Gorbunova,Boris Zhivotovsky,Gelina S Kopeina
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Dual targeting of SREBP2 and ERRα by carnosic acid suppresses RANKL-mediated osteoclastogenesis and prevents ovariectomy-induced bone loss. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-06 Zu-Guo Zheng,Hui-Min Cheng,Ya-Ping Zhou,Si-Tong Zhu,Pyone Myat Thu,Hui-Jun Li,Ping Li,Xiaojun Xu
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Coupling of terminal differentiation deficit with neurodegenerative pathology in Vps35-deficient pyramidal neurons. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-06 Fu-Lei Tang,Lu Zhao,Yang Zhao,Dong Sun,Xiao-Juan Zhu,Lin Mei,Wen-Cheng Xiong
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Chchd2 regulates mitochondrial morphology by modulating the levels of Opa1. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-06 Wei Liu,Xiuying Duan,Lingna Xu,Weina Shang,Jiayao Zhao,Liquan Wang,Jian-Chiuan Li,Chun-Hong Chen,Jun-Ping Liu,Chao Tong
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Autophagy and disease: unanswered questions Cell Death Differ. (IF 8.086) Pub Date : 2020-01-03 Ying Yang; Daniel J. Klionsky
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Autophagy, replication stress and DNA synthesis, an intricate relationship. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-03 Francesco Cecconi
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Autophagy and microbial pathogenesis Cell Death Differ. (IF 8.086) Pub Date : 2020-01-02 Matthew D. Keller; Victor J. Torres; Ken Cadwell
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Correction to: Impaired adult neurogenesis is an early event in Alzheimer's disease neurodegeneration, mediated by intracellular Aβ oligomers. Cell Death Differ. (IF 8.086) Pub Date : 2020-01-02 Chiara Scopa,Francesco Marrocco,Valentina Latina,Federica Ruggeri,Valerio Corvaglia,Federico La Regina,Martine Ammassari-Teule,Silvia Middei,Giuseppina Amadoro,Giovanni Meli,Raffaella Scardigli,Antonino Cattaneo
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Deubiquitinating enzyme USP33 restrains docetaxel-induced apoptosis via stabilising the phosphatase DUSP1 in prostate cancer. Cell Death Differ. (IF 8.086) Pub Date : 2019-12-19 Fei Guo,Chao Zhang,Fubo Wang,Wei Zhang,Xiaolei Shi,Yasheng Zhu,Ziyu Fang,Bo Yang,Yinghao Sun
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Correction to: Splicing factor derived circular RNA circUHRF1 accelerates oral squamous cell carcinoma tumorigenesis via feedback loop. Cell Death Differ. (IF 8.086) Pub Date : 2019-12-18 Wei Zhao,Yameng Cui,Lina Liu,Xiaoqian Qi,Jingwen Liu,Shiqing Ma,Xin Hu,Zheng Zhang,Yue Wang,Hongfa Li,Zuomin Wang,Zihao Liu,Jie Wu
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ATG12 deficiency leads to tumor cell oncosis owing to diminished mitochondrial biogenesis and reduced cellular bioenergetics. Cell Death Differ. (IF 8.086) Pub Date : 2019-12-16 He Liu,Zhaoyue He,Nina Germič,Hyrijie Ademi,Živa Frangež,Andrea Felser,Shuang Peng,Carsten Riether,Valentin Djonov,Jean-Marc Nuoffer,Cédric Bovet,Irena Mlinarič-Raščan,Inti Zlobec,Martin Fiedler,Aurel Perren,Hans-Uwe Simon
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Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients Cell Death Differ. (IF 8.086) Pub Date : 2019-12-13 Jean M. Mulcahy Levy; Andrew Thorburn
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Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways Cell Death Differ. (IF 8.086) Pub Date : 2019-12-12 Jessica Dittmann; Tinka Haydn; Patrick Metzger; George A. Ward; Melanie Boerries; Meike Vogler; Simone Fulda
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ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness. Cell Death Differ. (IF 8.086) Pub Date : 2019-12-12 Qingyu Luo,Xiaowei Wu,Wan Chang,Pengfei Zhao,Yabing Nan,Xiaolin Zhu,Jonathan P Katz,Dan Su,Zhihua Liu
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SPHK1 deficiency protects mice from acetaminophen-induced ER stress and mitochondrial permeability transition Cell Death Differ. (IF 8.086) Pub Date : 2019-12-11 Longjun Li, Haitao Wang, Jun Zhang, Yeqin Sha, Fengjiao Wu, Shuang Wen, Lianping He, Liang Sheng, Qiang You, Meiqing Shi, Lixin Liu, Hong Zhou
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Prohibitin levels regulate OMA1 activity and turnover in neurons. Cell Death Differ. (IF 8.086) Pub Date : 2019-12-09 Corey J Anderson,Anja Kahl,Hannah Fruitman,Liping Qian,Ping Zhou,Giovanni Manfredi,Costantino Iadecola
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Mitochondrial 4-HNE derived from MAO-A promotes mitoCa 2+ overload in chronic postischemic cardiac remodeling Cell Death Differ. (IF 8.086) Pub Date : 2019-12-09 Yohan Santin, Loubina Fazal, Yannis Sainte-Marie, Pierre Sicard, Damien Maggiorani, Florence Tortosa, Yasemin Yücel Yücel, Lise Teyssedre, Jacques Rouquette, Marlene Marcellin, Cécile Vindis, Jean C. Shih, Olivier Lairez, Odile Burlet-Schiltz, Angelo Parini, Frank Lezoualc’h, Jeanne Mialet-Perez
Contents have been reproduced by permission of the publishers.
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