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样式: 排序: IF: - GO 导出 标记为已读
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Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis Cell Death Differ. (IF 12.067) Pub Date : 2023-05-20 Chunfeng Liu, Matjaz Rokavec, Zekai Huang, Heiko Hermeking
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USP28 controls SREBP2 and the mevalonate pathway to drive tumour growth in squamous cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-05-18 Carina R. Maier, Oliver Hartmann, Cristian Prieto-Garcia, Kamal M. Al-Shami, Lisa Schlicker, Felix C. E. Vogel, Silke Haid, Kevin Klann, Viktoria Buck, Christian Münch, Werner Schmitz, Elias Einig, Bastian Krenz, Marco A. Calzado, Martin Eilers, Nikita Popov, Mathias T. Rosenfeldt, Markus E. Diefenbacher, Almut Schulze
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SUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1 Cell Death Differ. (IF 12.067) Pub Date : 2023-05-15 Xiao Wu, Jian-Hui Li, Long Xu, Ya-Xiong Li, Xiao-Xu Zhu, Xi-Yu Wang, Xingmei Wu, Wei Zhao, Xuhao Ni, Xiao-Yu Yin
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The deubiquitylating enzyme USP35 restricts regulated cell death to promote survival of renal clear cell carcinoma Cell Death Differ. (IF 12.067) Pub Date : 2023-05-12 Shanshan Wang, Taishu Wang, Xuehong Zhang, Shaoxuan Cheng, Chaoqun Chen, Guoheng Yang, Fuqiang Wang, Ruilin Wang, Qingqing Zhang, Dian Yang, Yingqiu Zhang, Shuyan Liu, Hongqiang Qin, Quentin Liu, Han Liu
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Circular RNA circRILPL1 promotes nasopharyngeal carcinoma malignant progression by activating the Hippo-YAP signaling pathway Cell Death Differ. (IF 12.067) Pub Date : 2023-05-12 Pan Wu, Xiangchan Hou, Miao Peng, Xiangying Deng, Qijia Yan, Chunmei Fan, Yongzhen Mo, Yumin Wang, Zheng Li, Fuyan Wang, Can Guo, Ming Zhou, Qianjin Liao, Hui Wang, Zhaoyang Zeng, Weihong Jiang, Guiyuan Li, Wei Xiong, Bo Xiang
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p53-dependent DNA repair during the DNA damage response requires actin nucleation by JMY Cell Death Differ. (IF 12.067) Pub Date : 2023-05-04 Ignacio Rodriguez-Pastrana, Eleni Birli, Amanda S. Coutts
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Actionable cancer vulnerability due to translational arrest, p53 aggregation and ribosome biogenesis stress evoked by the disulfiram metabolite CuET Cell Death Differ. (IF 12.067) Pub Date : 2023-05-04 Dimitris C. Kanellis, Asimina Zisi, Zdenek Skrott, Bennie Lemmens, Jaime A. Espinoza, Martin Kosar, Andrea Björkman, Xuexin Li, Stefanos Arampatzis, Jirina Bartkova, Miguel Andújar-Sánchez, Oscar Fernandez-Capetillo, Martin Mistrik, Mikael S. Lindström, Jiri Bartek
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KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility Cell Death Differ. (IF 12.067) Pub Date : 2023-05-04 Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
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Activated KRAS, polyamines, iASPP and TME: a multiple liaison in pancreatic cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-04-29 Giovanni Blandino
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Collagen I-DDR1 signaling promotes hepatocellular carcinoma cell stemness via Hippo signaling repression Cell Death Differ. (IF 12.067) Pub Date : 2023-04-28 Yi-xiao Xiong, Xiao-chao Zhang, Jing-han Zhu, Yu-xin Zhang, Yong-long Pan, Yu Wu, Jian-ping Zhao, Jun-jie Liu, Yuan-xiang Lu, Hui-fang Liang, Zhan-guo Zhang, Wan-guang Zhang
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Apoptotic cell death in disease—Current understanding of the NCCD 2023 Cell Death Differ. (IF 12.067) Pub Date : 2023-04-26 Ilio Vitale, Federico Pietrocola, Emma Guilbaud, Stuart A. Aaronson, John M. Abrams, Dieter Adam, Massimiliano Agostini, Patrizia Agostinis, Emad S. Alnemri, Lucia Altucci, Ivano Amelio, David W. Andrews, Rami I. Aqeilan, Eli Arama, Eric H. Baehrecke, Siddharth Balachandran, Daniele Bano, Nickolai A. Barlev, Jiri Bartek, Nicolas G. Bazan, Christoph Becker, Francesca Bernassola, Mathieu J. M. Bertrand
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The biophysical property of the limbal niche maintains stemness through YAP Cell Death Differ. (IF 12.067) Pub Date : 2023-04-24 Swarnabh Bhattacharya, Abhishek Mukherjee, Sabrina Pisano, Shalini Dimri, Eman Knaane, Anna Altshuler, Waseem Nasser, Sunanda Dey, Lidan Shi, Ido Mizrahi, Noam Blum, Ophir Jokel, Aya Amitai-Lange, Anna Kaganovsky, Michael Mimouni, Sergiu Socea, Mohamad Midlij, Beatrice Tiosano, Peleg Hasson, Chloe Feral, Haguy Wolfenson, Ruby Shalom-Feuerstein
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Telomerase deficiency and dysfunctional telomeres in the lung tumor microenvironment impair tumor progression in NSCLC mouse models and patient-derived xenografts Cell Death Differ. (IF 12.067) Pub Date : 2023-04-21 Sergio Piñeiro-Hermida, Giuseppe Bosso, Raúl Sánchez-Vázquez, Paula Martínez, Maria A. Blasco
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IKK-mediated TRAF6 and RIPK1 interaction stifles cell death complex assembly leading to the suppression of TNF-α-induced cell death Cell Death Differ. (IF 12.067) Pub Date : 2023-04-21 Choong-Sil Lee, Gyuho Hwang, Young Woo Nam, Chi Hyun Hwang, Jaewhan Song
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The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway Cell Death Differ. (IF 12.067) Pub Date : 2023-04-20 Xue Liang, Jiping Yao, Danrui Cui, Weiyang Zheng, Yanning Liu, Guohua Lou, Bingjue Ye, Liyan Shui, Yi Sun, Yongchao Zhao, Min Zheng
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The embryonic patterning gene Dbx1 governs the survival of the auditory midbrain via Tcf7l2-Ap2δ transcriptional cascade Cell Death Differ. (IF 12.067) Pub Date : 2023-04-20 Hong-Nhung Tran, Quy-Hoai Nguyen, Ji-eun Jeong, Duc-Linh Loi, Youn Hee Nam, Tong Ho Kang, Jaeseung Yoon, Kwanghee Baek, Yongsu Jeong
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Inhibition of USP14 promotes TNFα-induced cell death in head and neck squamous cell carcinoma (HNSCC) Cell Death Differ. (IF 12.067) Pub Date : 2023-04-13 Ethan L. Morgan, Tiffany Toni, Ramya Viswanathan, Yvette Robbins, Xinping Yang, Hui Cheng, Sreenivasulu Gunti, Angel Huynh, Anastasia L. Sowers, James B. Mitchell, Clint T. Allen, Zhong Chen, Carter Van Waes
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Transcriptional regulation of autophagy and its implications in human disease Cell Death Differ. (IF 12.067) Pub Date : 2023-04-12 Yuchen Lei, Daniel J. Klionsky
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Regulating GSDMB pore formation: to ignite or inhibit? Cell Death Differ. (IF 12.067) Pub Date : 2023-04-11 Jianbin Ruan
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Long non-coding RNA HIF1A-As2 and MYC form a double-positive feedback loop to promote cell proliferation and metastasis in KRAS-driven non-small cell lung cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-04-11 Kaixin Yang, Wenyang Zhang, Linghui Zhong, Yinan Xiao, Sudhakar Sahoo, Matteo Fassan, Kang Zeng, Peter Magee, Michela Garofalo, Lei Shi
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The hunger strikes back: an epigenetic memory for autophagy Cell Death Differ. (IF 12.067) Pub Date : 2023-04-08 Patricia González-Rodríguez, Jens Füllgrabe, Bertrand Joseph
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LncRNA GLTC targets LDHA for succinylation and enzymatic activity to promote progression and radioiodine resistance in papillary thyroid cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-04-08 Liang Shi, Rui Duan, Zhenhua Sun, Qiong Jia, Wenyu Wu, Feng Wang, Jianjun Liu, Hao Zhang, Xue Xue
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BCL-G: 20 years of research on a non-typical protein from the BCL-2 family Cell Death Differ. (IF 12.067) Pub Date : 2023-04-08 Mariusz L. Hartman, Malgorzata Czyz
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Developmental growth plate cartilage formation suppressed by artificial light at night via inhibiting BMAL1-driven collagen hydroxylation Cell Death Differ. (IF 12.067) Pub Date : 2023-04-07 Guangjin Chen, Qingming Tang, Shaoling Yu, Yufeng Shen, Jiwei Sun, Jinfeng Peng, Ying Yin, Guangxia Feng, Xiaofeng Lu, Gang Mei, Yifan Zhang, Qian Wan, Luoying Zhang, Lili Chen
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CRL4B complex-mediated H2AK119 monoubiquitination restrains Th1 and Th2 cell differentiation Cell Death Differ. (IF 12.067) Pub Date : 2023-04-06 Liping Qin, Yu Song, Fan Zhang, Ru Wang, Li Zhou, Shiqi Jin, Chaojia Chen, Chunyang Li, Molin Wang, Baichun Jiang, Gongping Sun, Chunhong Ma, Yaoqin Gong, Peishan Li
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Epigenetic regulation of autophagy by histone-modifying enzymes under nutrient stress Cell Death Differ. (IF 12.067) Pub Date : 2023-03-30 Young Suk Yu, Hyunkyung Kim, Keun Il Kim, Sung Hee Baek
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SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation Cell Death Differ. (IF 12.067) Pub Date : 2023-03-25 Lilia Sanchez, Jessica Epps, Steven Wall, Cole McQueen, Scott J. Pearson, Kelly Scribner, Elizabeth A. Wellberg, Erin D. Giles, Monique Rijnkels, Weston W. Porter
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EMSY stabilization in KEAP1-mutant lung cancer disrupts genome stability and type I interferon signaling Cell Death Differ. (IF 12.067) Pub Date : 2023-03-23 Daoud Sheban, Yifat Merbl
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Deubiquitinase OTUD6A in macrophages promotes intestinal inflammation and colitis via deubiquitination of NLRP3 Cell Death Differ. (IF 12.067) Pub Date : 2023-03-17 Xin Liu, Yi Fang, Xinting Lv, Chenghong Hu, Guorong Chen, Lingxi Zhang, Bo Jin, Lijiang Huang, Wu Luo, Guang Liang, Yi Wang
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Doublecortin-like kinase 1 activates NF-κB to induce inflammatory responses by binding directly to IKKβ Cell Death Differ. (IF 12.067) Pub Date : 2023-03-13 Wu Luo, Yiyi Jin, Yuchen Jiang, Libin Yang, Haowen Xu, Di Wu, Yanmei Zhang, Lina Yin, Zia Ali Khan, Guang Liang, Yi Wang
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Histone demethylase KDM5B licenses macrophage-mediated inflammatory responses by repressing Nfkbia transcription Cell Death Differ. (IF 12.067) Pub Date : 2023-03-13 Yunkai Zhang, Ying Gao, Yuyu Jiang, Yingying Ding, Huiying Chen, Yan Xiang, Zhenzhen Zhan, Xingguang Liu
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Distinct GSDMB protein isoforms and protease cleavage processes differentially control pyroptotic cell death and mitochondrial damage in cancer cells Cell Death Differ. (IF 12.067) Pub Date : 2023-03-11 Sara S. Oltra, Sara Colomo, Laura Sin, María Pérez-López, Sara Lázaro, Angela Molina-Crespo, Kyoung-Han Choi, David Ros-Pardo, Lidia Martínez, Saleta Morales, Cristina González-Paramos, Alba Orantes, Mario Soriano, Alberto Hernández, Ana Lluch, Federico Rojo, Joan Albanell, Paulino Gómez-Puertas, Jae-Kyun Ko, David Sarrió, Gema Moreno-Bueno
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Deletion of the transcriptional regulator TFAP4 accelerates c-MYC-driven lymphomagenesis Cell Death Differ. (IF 12.067) Pub Date : 2023-03-09 Margaret A. Potts, Shinsuke Mizutani, Alexandra L. Garnham, Connie S. N. Li Wai Suen, Andrew J. Kueh, Lin Tai, Martin Pal, Andreas Strasser, Marco J. Herold
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Targeting HDAC3 to overcome the resistance to ATRA or arsenic in acute promyelocytic leukemia through ubiquitination and degradation of PML-RARα Cell Death Differ. (IF 12.067) Pub Date : 2023-03-09 Bo Dai, Feng Wang, Ying Wang, Jiayan Zhu, Yunxuan Li, Tingting Zhang, Luyao Zhao, Lining Wang, Wenhui Gao, Junmin Li, Honghu Zhu, Ke Li, Jiong Hu
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A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner Cell Death Differ. (IF 12.067) Pub Date : 2023-03-03 Sandrine Ragu, Nathalie Droin, Gabriel Matos-Rodrigues, Aurélia Barascu, Sylvain Caillat, Gabriella Zarkovic, Capucine Siberchicot, Elodie Dardillac, Camille Gelot, Josée Guirouilh-Barbat, J. Pablo Radicella, Alexander A. Ishchenko, Jean-Luc Ravanat, Eric Solary, Bernard S. Lopez
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Human skin specific long noncoding RNA HOXC13-AS regulates epidermal differentiation by interfering with Golgi-ER retrograde transport Cell Death Differ. (IF 12.067) Pub Date : 2023-03-03 Letian Zhang, Minna Piipponen, Zhuang Liu, Dongqing Li, Xiaowei Bian, Guanglin Niu, Jennifer Geara, Maria A. Toma, Pehr Sommar, Ning Xu Landén
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Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification Cell Death Differ. (IF 12.067) Pub Date : 2023-03-02 Ozge Saatci, Ozge Akbulut, Metin Cetin, Vitali Sikirzhytski, Meral Uner, Deniz Lengerli, Elizabeth C. O’Quinn, Martin J. Romeo, Burcu Caliskan, Erden Banoglu, Sercan Aksoy, Aysegul Uner, Ozgur Sahin
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DNA 5mC and RNA m6A modification successively facilitates the initiation and perpetuation stages of HSC activation in liver fibrosis progression Cell Death Differ. (IF 12.067) Pub Date : 2023-02-25 Yue Feng, Shihui Guo, Yulan Zhao, Haibo Dong, Jiayu Qian, Yun Hu, Lei Wu, Yimin Jia, Ruqian Zhao
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BAP18 facilitates CTCF-mediated chromatin accessible to regulate enhancer activity in breast cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-02-24 Ge Sun, Yuntao Wei, Baosheng Zhou, Manlin Wang, Ruina Luan, Yu Bai, Hao Li, Shan Wang, Dantong Zheng, Chunyu Wang, Shengli Wang, Kai Zeng, Shuchang Liu, Lin Lin, Mingcong He, Qiang Zhang, Yue Zhao
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A novel tumor suppressor encoded by a 1p36.3 lncRNA functions as a phosphoinositide-binding protein repressing AKT phosphorylation/activation and promoting autophagy Cell Death Differ. (IF 12.067) Pub Date : 2023-02-23 Lili Li, Xing-sheng Shu, Hua Geng, Jianming Ying, Lei Guo, Jie Luo, Tingxiu Xiang, Longtao Wu, Brigette B. Y. Ma, Anthony T. C. Chan, Xiaofeng Zhu, Richard F. Ambinder, Qian Tao
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S100 family proteins are linked to organoid morphology and EMT in pancreatic cancer Cell Death Differ. (IF 12.067) Pub Date : 2023-02-24 Ronnie Ren Jie Low, Ka Yee Fung, Hugh Gao, Adele Preaudet, Laura F. Dagley, Jumana Yousef, Belinda Lee, Samantha J. Emery-Corbin, Rune H. Larsen, Nadia J. Kershaw, Antony W. Burgess, Peter Gibbs, Frédéric Hollande, Michael D. W. Griffin, Sean M. Grimmond, Tracy L. Putoczki
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N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2 Cell Death Differ. (IF 12.067) Pub Date : 2023-02-24 Haibo Xia, Yan Wu, Jing Zhao, Cheng Cheng, Jiaheng Lin, Yi Yang, Lu Lu, Quanyong Xiang, Tao Bian, Qizhan Liu
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PIN1 and CDK1 cooperatively govern pVHL stability and suppressive functions Cell Death Differ. (IF 12.067) Pub Date : 2023-02-23 Jiayi Chen, Mei Li, Yeqing Liu, Tangming Guan, Xiao Yang, Yalei Wen, Yingjie Zhu, Zeyu Xiao, Xiangchun Shen, Haoxing Zhang, Hui Tang, Tongzheng Liu
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Lineage tracing of mutant granulosa cells reveals in vivo protective mechanisms that prevent granulosa cell tumorigenesis Cell Death Differ. (IF 12.067) Pub Date : 2023-02-23 Shudong Niu, Kaixin Cheng, Longzhong Jia, Jing Liang, Lu Mu, Yibo Wang, Xuebing Yang, Chen Yang, Yan Zhang, Chao Wang, Lijun Huang, Huarong Wang, Shuang Zhang, Hua Zhang
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PDLIM3 supports hedgehog signaling in medulloblastoma by facilitating cilia formation Cell Death Differ. (IF 12.067) Pub Date : 2023-02-22 Jie Zhang, Yijun Yang, Xinhua Li, Gen Li, Takuya Mizukami, Yanli Liu, Yuan Wang, Guoqiang Xu, Heinrich Roder, Li Zhang, Zeng-jie Yang
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The deubiquitinating enzyme UCHL3 promotes anaplastic thyroid cancer progression and metastasis through Hippo signaling pathway Cell Death Differ. (IF 12.067) Pub Date : 2023-02-22 Jianing Tang, Qian Yang, Chao Mao, Desheng Xiao, Shuang Liu, Liang Xiao, Ledu Zhou, Gaosong Wu, Yongguang Tao
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To not love thy neighbor: mechanisms of cell competition in stem cells and beyond Cell Death Differ. (IF 12.067) Pub Date : 2023-02-22 Marianna Yusupova, Yaron Fuchs
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The p53 endoplasmic reticulum stress-response pathway evolved in humans but not in mice via PERK-regulated p53 mRNA structures Cell Death Differ. (IF 12.067) Pub Date : 2023-02-22 Leila Fusée, Norman Salomao, Anand Ponnuswamy, Lixiao Wang, Ignacio López, Sa Chen, Xiaolian Gu, Stavros Polyzoidis, Sivakumar Vadivel Gnanasundram, Robin Fahraeus
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CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death Cell Death Differ. (IF 12.067) Pub Date : 2023-02-18 Neil Kuehnle, Scout Mask Osborne, Ziyan Liang, Mark Manzano, Eva Gottwein
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Mechanisms controlling plant proteases and their substrates Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Álvaro Daniel Fernández-Fernández, Simon Stael, Frank Van Breusegem
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Tissue specificity and spatio-temporal dynamics of the p53 transcriptional program Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Vinod Pant, Chang Sun, Guillermina Lozano
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MNT suppresses T cell apoptosis via BIM and is critical for T lymphomagenesis Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Hai Vu Nguyen, Cassandra J. Vandenberg, Mikara R. Robati, Ashley P. Ng, Suzanne Cory
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MLKL deficiency protects against low-grade, sterile inflammation in aged mice Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Emma C. Tovey Crutchfield, Sarah E. Garnish, Jessica Day, Holly Anderton, Shene Chiou, Anne Hempel, Cathrine Hall, Komal M. Patel, Pradnya Gangatirkar, Katherine R. Martin, Connie S. N. Li Wai Suen, Alexandra L. Garnham, Andrew J. Kueh, Ian P. Wicks, John Silke, Ueli Nachbur, Andre L. Samson, James M. Murphy, Joanne M. Hildebrand
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Lymphoma cells lacking pro-apoptotic BAX are highly resistant to BH3-mimetics targeting pro-survival MCL-1 but retain sensitivity to conventional DNA-damaging drugs Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Sarah T. Diepstraten, Savannah Young, John E. La Marca, Zilu Wang, Ruth M. Kluck, Andreas Strasser, Gemma L. Kelly
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Moonlighting chromatin: when DNA escapes nuclear control Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Jeeshan Singh, Michael Boettcher, Maximilian Dölling, Annika Heuer, Bettina Hohberger, Moritz Leppkes, Elisabeth Naschberger, Mirco Schapher, Christine Schauer, Janina Schoen, Michael Stürzl, Ljubomir Vitkov, Han Wang, Leticija Zlatar, Georg A. Schett, David S. Pisetsky, Ming-Lin Liu, Martin Herrmann, Jasmin Knopf
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Cuproptosis: p53-regulated metabolic cell death? Cell Death Differ. (IF 12.067) Pub Date : 2023-02-08 Chen Xiong, Hong Ling, Qian Hao, Xiang Zhou
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The regulation loop of MARVELD1 interacting with PARP1 in DNA damage response maintains genome stability and promotes therapy resistance of cancer cells Cell Death Differ. (IF 12.067) Pub Date : 2023-02-07 Haoxiu Sun, Chao Liu, Fang Han, Xiaoyu Lin, Liangyu Cao, Chenxing Liu, Qiuyu Ji, Jinjin Cui, Yuanfei Yao, Bojun Wang, Yuanyu liao, Huan Nie, Yanqiao Zhang, Yu Li
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The anti-cancer agent APR-246 can activate several programmed cell death processes to kill malignant cells Cell Death Differ. (IF 12.067) Pub Date : 2023-02-04 Zilu Wang, Huimin Hu, Luuk Heitink, Kelly Rogers, Yue You, Tao Tan, Connie Li Wai Suen, Alex Garnham, Hao Chen, Elizabeth Lieschke, Sarah T. Diepstraten, Catherine Chang, Diane Moujalled, Kate Sutherland, Guillaume Lessene, Oliver M. Sieber, Jane Visvader, Gemma L. Kelly, Andreas Strasser
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Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs Cell Death Differ. (IF 12.067) Pub Date : 2023-01-24 Nicolás A. Pinto, Martín C. Abba, Lorena Laporte, Juan M. Pérez Sáez, Ada G. Blidner, Nicolás I. Torres, Rosa M. Morales, Sabrina G. Gatto, Camila A. Bach, Florencia Veigas, Hernán J. García Rivello, Peng Song, Jane H. Frederiksen, Lene Juel Rasmussen, Francoise Poirier, Diego O. Croci, Victoria Sundblad, Gabriel A. Rabinovich, Juan P. Cerliani
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CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity Cell Death Differ. (IF 12.067) Pub Date : 2023-01-21 Hansen Liu, Zhenzhen Yan, Deyu Zhu, Haiyan Xu, Feng Liu, Tian Chen, Honghai Zhang, Yi Zheng, Bingyu Liu, Lei Zhang, Wei Zhao, Chengjiang Gao