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Growth of the maternal intestine during reproduction Cell (IF 45.5) Pub Date : 2025-04-26 Tomotsune Ameku, Anna Laddach, Hannah Beckwith, Alexandra Milona, Loranzie S. Rogers, Cornelia Schwayer, Emma Nye, Iain R. Tough, Jean-Louis Thoumas, Umesh Kumar Gautam, Yi-Fang Wang, Shreya Jha, Alvaro Castano-Medina, Christopher Amourda, Patric M. Vaelli, Sira Gevers, Elaine E. Irvine, Leah Meyer, Ivan Andrew, Ka Lok Choi, Irene Miguel-Aliaga
(Cell 188, ◼◼◼–◼◼◼.e1–e22; May 15, 2025)
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Conserved genetic basis for microbial colonization of the gut Cell (IF 45.5) Pub Date : 2025-04-25 Menghan Liu, Sydney B. Blattman, Mai Takahashi, Nandan Mandayam, Wenyan Jiang, Panos Oikonomou, Sohail F. Tavazoie, Saeed Tavazoie
(Cell 188, ▪▪▪.e1–e22; May 1, 2025)
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RNA polymerase II partitioning is a shared feature of diverse oncofusion condensates Cell (IF 45.5) Pub Date : 2025-04-25 Heankel Lyons, Prashant Pradhan, Gopinath Prakasam, Shubham Vashishtha, Xiang Li, Mikayla Eppert, Christy Fornero, Vanina T. Tcheuyap, Kathleen McGlynn, Ze Yu, Dinesh Ravindra Raju, Prasad R. Koduru, Chao Xing, Payal Kapur, James Brugarolas, Benjamin R. Sabari
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Neuron-astrocyte coupling in lateral habenula mediates depressive-like behaviors Cell (IF 45.5) Pub Date : 2025-04-24 Qianqian Xin, Junying Wang, Jinkun Zheng, Yi Tan, Xiaoning Jia, Zheyi Ni, Zijie Xu, Jiesi Feng, Zhaofa Wu, Yulong Li, Xiao-Ming Li, Huan Ma, Hailan Hu
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SLC7A11 is an unconventional H+ transporter in lysosomes Cell (IF 45.5) Pub Date : 2025-04-24 Nan Zhou, Jingzhi Chen, Meiqin Hu, Na Wen, Weijie Cai, Ping Li, Liding Zhao, Yaping Meng, Dongdong Zhao, Xiaotong Yang, Siyu Liu, Fangqian Huang, Cheng Zhao, Xinghua Feng, Zikai Jiang, Enjun Xie, Hongxu Pan, Zhidong Cen, Xinhui Chen, Wei Luo, Beisha Tang, Junxia Min, Fudi Wang, Junsheng Yang, Haoxing Xu
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Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias Cell (IF 45.5) Pub Date : 2025-04-23 Won Jun Kim, Edie I. Crosse, Emma De Neef, Inaki Etxeberria, Erich Y. Sabio, Eric Wang, Jan Philipp Bewersdorf, Kuan-Ting Lin, Sydney X. Lu, Andrea Belleville, Nina Fox, Cynthia Castro, Pu Zhang, Takeshi Fujino, Jennifer Lewis, Jahan Rahman, Beatrice Zhang, Jacob H. Winick, Alexander M. Lewis, Robert F. Stanley, Omar Abdel-Wahab
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Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer’s disease Cell (IF 45.5) Pub Date : 2025-04-23 Junchen Chen, Fatemeh Hadi, Xingzhao Wen, Wenxin Zhao, Ming Xu, Shuanghong Xue, Pei Lin, Riccardo Calandrelli, John Lalith Charles Richard, Zhixuan Song, Jessica Li, Alborz Amani, Yang Liu, Xu Chen, Sheng Zhong
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Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network Cell (IF 45.5) Pub Date : 2025-04-23 Andrew B. Kleist, Martyna Szpakowska, Lindsay J. Talbot, Greg Slodkowicz, Duccio Malinverni, Monica A. Thomas, Kyler S. Crawford, Daniel J. McGrail, Acacia F. Dishman, Michael J. Wedemeyer, Madison Sluter, S. Stephen Yi, Nidhi Sahni, Francis C. Peterson, Andy Chevigné, Brian F. Volkman, M. Madan Babu
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The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways Cell (IF 45.5) Pub Date : 2025-04-23 Mrinmoy Pal, Tamas Schauer, Adam Burton, Tsunetoshi Nakatani, Federico Pecori, Alicia Hernández-Giménez, Iliya Nadelson, Marc A. Marti-Renom, Maria-Elena Torres-Padilla
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Hypothalamic PNOC/NPY neurons constitute mediators of leptin-controlled energy homeostasis Cell (IF 45.5) Pub Date : 2025-04-23 Marie H. Solheim, Sima Stroganov, Weiyi Chen, P. Sicilia Subagia, Corinna A. Bauder, Daria Wnuk-Lipinski, Almudena Del Río-Martín, Tamara Sotelo-Hitschfeld, Cait A. Beddows, Paul Klemm, Garron T. Dodd, Sofia Lundh, Anna Secher, F. Thomas Wunderlich, Lukas Steuernagel, Jens C. Brüning
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Root microbiota regulates tiller number in rice Cell (IF 45.5) Pub Date : 2025-04-22 Jingying Zhang, Bing Wang, Haoran Xu, Weidong Liu, Jingwei Yu, Qiuxia Wang, Hong Yu, Jin-Wei Wei, Rui Dai, Jinghang Zhou, Yuhang He, Di Zou, Jinhua Yang, Xinwei Ban, Qingliang Hu, Xiangbing Meng, Yong-Xin Liu, Binglei Wang, Bin Hu, Mingyu Wang, Yang Bai
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection Cell (IF 45.5) Pub Date : 2025-04-22 Susan Westfall, Maria E. Gentile, Tayla M. Olsen, Danielle Karo-Atar, Andrei Bogza, Franziska Röstel, Ryan D. Pardy, Giordano Mandato, Ghislaine Fontes, De’Broski Herbert, Heather J. Melichar, Valerie Abadie, Martin J. Richer, Donald C. Vinh, Joshua F.E. Koenig, Oliver J. Harrison, Maziar Divangahi, Sebastian Weis, Alex Gregorieff, Irah L. King
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A cognitive map for value-guided choice in the ventromedial prefrontal cortex Cell (IF 45.5) Pub Date : 2025-04-21 Sebastijan Veselic, Timothy H. Muller, Elena Gutierrez, Timothy E.J. Behrens, Laurence T. Hunt, James L. Butler, Steven W. Kennerley
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Tissue geometry spatiotemporally drives bacterial infections Cell (IF 45.5) Pub Date : 2025-04-21 Yiming Han, Xiaoye Liu, Shaoqi Qu, Xiaocen Duan, Yunqing Xiang, Nan Jiang, Shuyu Yang, Xu Fang, Liang Xu, Hui Wen, Yue Yu, Shuqiang Huang, Jianyong Huang, Kui Zhu
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Red blood cells undergo lytic programmed cell death involving NLRP3 Cell (IF 45.5) Pub Date : 2025-04-18 Yaozhen Chen, Shouwen Chen, Zhixin Liu, Yafen Wang, Ning An, Yutong Chen, Yihao Peng, Zheng Liu, Qin Liu, Xingbin Hu
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Fate and state transitions during human blood vessel organoid development Cell (IF 45.5) Pub Date : 2025-04-17 Marina T. Nikolova, Zhisong He, Makiko Seimiya, Gustav Jonsson, Wuji Cao, Ryo Okuda, Reiner A. Wimmer, Ryoko Okamoto, Josef M. Penninger, J. Gray Camp, Barbara Treutlein
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CD36-mediated endocytosis of proteolysis-targeting chimeras Cell (IF 45.5) Pub Date : 2025-04-17 Zhengyu Wang, Bo-Syong Pan, Rajesh Kumar Manne, Jungang Chen, Dongwen Lv, Minmin Wang, Phuc Tran, Tsigereda Weldemichael, Wei Yan, Hongfei Zhou, Gloria M. Martinez, Jingwei Shao, Che-Chia Hsu, Robert Hromas, Daohong Zhou, Zhiqiang Qin, Hui-Kuan Lin, Hong-Yu Li
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Nutrient-regulated control of lysosome function by signaling lipid conversion Cell (IF 45.5) Pub Date : 2025-04-17 Michael Ebner, Dmytro Puchkov, Orestes López-Ortega, Pathma Muthukottiappan, Yanwei Su, Christopher Schmied, Silke Zillmann, Iryna Nikonenko, Jochen Koddebusch, Gillian L. Dornan, Max T. Lucht, Vonda Koka, Wonyul Jang, Philipp Alexander Koch, Alexander Wallroth, Martin Lehmann, Britta Brügger, Mario Pende, Dominic Winter, Volker Haucke
(Cell 186, 5328–5346.e1–e12; November 22, 2023)
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From geroscience to precision geromedicine: Understanding and managing aging Cell (IF 45.5) Pub Date : 2025-04-17 Guido Kroemer, Andrea B. Maier, Ana Maria Cuervo, Vadim N. Gladyshev, Luigi Ferrucci, Vera Gorbunova, Brian K. Kennedy, Thomas A. Rando, Andrei Seluanov, Felipe Sierra, Eric Verdin, Carlos López-Otín
Major progress has been made in elucidating the molecular, cellular, and supracellular mechanisms underlying aging. This has spurred the birth of geroscience, which aims to identify actionable hallmarks of aging. Aging can be viewed as a process that is promoted by overactivation of gerogenes, i.e., genes and molecular pathways that favor biological aging, and alternatively slowed down by gerosuppressors
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Rewriting regulatory DNA to dissect and reprogram gene expression Cell (IF 45.5) Pub Date : 2025-04-16 Gabriella E. Martyn, Michael T. Montgomery, Hank Jones, Katherine Guo, Benjamin R. Doughty, Johannes Linder, Deepa Bisht, Fan Xia, Xiangmeng S. Cai, Ziwei Chen, Kelly Cochran, Kathryn A. Lawrence, Glen Munson, Anusri Pampari, Charles P. Fulco, Nidhi Sahni, David R. Kelley, Eric S. Lander, Anshul Kundaje, Jesse M. Engreitz
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High-resolution dynamic imaging of chromatin DNA communication using Oligo-LiveFISH Cell (IF 45.5) Pub Date : 2025-04-15 Yanyu Zhu, Ashwin Balaji, Mengting Han, Leonid Andronov, Anish R. Roy, Zheng Wei, Crystal Chen, Leanne Miles, Sa Cai, Zhengxi Gu, Ariana Tse, Betty Chentzu Yu, Takeshi Uenaka, Xueqiu Lin, Andrew J. Spakowitz, W.E. Moerner, Lei S. Qi
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Synthetic deconvolution of an auxin-dependent transcriptional code Cell (IF 45.5) Pub Date : 2025-04-15 Raquel Martin-Arevalillo, Bruno Guillotin, Jonas Schön, Alice Hugues, Marie-France Gerentes, Kun Tang, Jérémy Lucas, Emmanuel Thévenon, Marianne Dreuillet, Graeme Vissers, Mohammed Mohammed Ateequr, Carlos S. Galvan-Ampudia, Guillaume Cerutti, Jonathan Legrand, Coralie Cance, Annick Dubois, François Parcy, Kenneth D. Birnbaum, Matias D. Zurbriggen, Renaud Dumas, Teva Vernoux
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Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity Cell (IF 45.5) Pub Date : 2025-04-15 Wen-Bing Jin, Leyi Xiao, Mingeum Jeong, Seong-Ji Han, Wen Zhang, Hiroshi Yano, Huiqing Shi, Mohammad Arifuzzaman, Mengze Lyu, Daoming Wang, Yuelin Angelina Tang, Shanshan Qiao, Xiaoyu Yang, He S. Yang, Jingyuan Fu, Gregory F. Sonnenberg, Nicholas Collins, David Artis, Chun-Jun Guo
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DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation Cell (IF 45.5) Pub Date : 2025-04-15 Shady Saad, Tomek Swigut, Saman Tabatabaee, Pranav Lalgudi, Daniel F. Jarosz, Joanna Wysocka
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Structure and infection dynamics of mycobacteriophage Bxb1 Cell (IF 45.5) Pub Date : 2025-04-15 Krista G. Freeman, Sudipta Mondal, Lourriel S. Macale, Jennifer Podgorski, Simon J. White, Benjamin H. Silva, Valery Ortiz, Alexis Huet, Ronelito J. Perez, Joemark T. Narsico, Meng-Chiao Ho, Deborah Jacobs-Sera, Todd L. Lowary, James F. Conway, Donghyun Park, Graham F. Hatfull
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Integrator loss leads to dsRNA formation that triggers the integrated stress response Cell (IF 45.5) Pub Date : 2025-04-14 Apoorva Baluapuri, Nicole ChenCheng Zhao, Ryan J. Marina, Kai-Lieh Huang, Anastasia Kuzkina, Maria E. Amodeo, Chad B. Stein, Lucie Y. Ahn, Jordan S. Farr, Ashleigh E. Schaffer, Vikram Khurana, Eric J. Wagner, Karen Adelman
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A two-step self-pollination mechanism maximizes fertility in Brassicaceae Cell (IF 45.5) Pub Date : 2025-04-14 Pu Liu, Xin Quan, Zihan Song, Wenhao Li, Yuan Wang, Hongya Gu, Daoxin Xie, Weicai Yang, Thomas Dresselhaus, Sheng Zhong, Li-Jia Qu
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Precision proteogenomics reveals pan-cancer impact of germline variants Cell (IF 45.5) Pub Date : 2025-04-14 Fernanda Martins Rodrigues, Nadezhda V. Terekhanova, Kathleen J. Imbach, Karl R. Clauser, Myvizhi Esai Selvan, Isabel Mendizabal, Yifat Geffen, Yo Akiyama, Myranda Maynard, Tomer M. Yaron, Yize Li, Song Cao, Erik P. Storrs, Olivia S. Gonda, Adrian Gaite-Reguero, Akshay Govindan, Emily A. Kawaler, Matthew A. Wyczalkowski, Robert J. Klein, Berk Turhan, Yige Wu
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ALDH7A1 protects against ferroptosis by generating membrane NADH and regulating FSP1 Cell (IF 45.5) Pub Date : 2025-04-14 Jia-Shu Yang, Andrew J. Morris, Koki Kamizaki, Jianzhong Chen, Jillian Stark, William M. Oldham, Toshitaka Nakamura, Eikan Mishima, Joseph Loscalzo, Yasuhiro Minami, Marcus Conrad, Whitney S. Henry, Victor W. Hsu
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Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity Cell (IF 45.5) Pub Date : 2025-04-11 Taisuke Kondo, François X.P. Bourassa, Sooraj Achar, Justyn DuSold, Pablo F. Céspedes, Makoto Ando, Alka Dwivedi, Josquin Moraly, Christopher Chien, Saliha Majdoul, Adam L. Kenet, Madison Wahlsten, Audun Kvalvaag, Edward Jenkins, Sanghyun P. Kim, Catherine M. Ade, Zhiya Yu, Guillaume Gaud, Marco Davila, Paul Love, Naomi Taylor
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An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation Cell (IF 45.5) Pub Date : 2025-04-11 Xing Guo, Yichuan Wang, Caiyao Zhao, Cong Tan, Wei Yan, Sunhuan Xiang, Dan Zhang, Hui Zhang, Mengting Zhang, Liujing Yang, Meng Yan, Pingli Xie, Yi Wang, Li Li, Dongming Fang, Xuanmin Guang, Wenwen Shao, Fang Wang, Haoxuan Wang, Sunil Kumar Sahu, Xun Xu
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Extracellular respiration is a latent energy metabolism in Escherichia coli Cell (IF 45.5) Pub Date : 2025-04-10 Biki Bapi Kundu, Jayanth Krishnan, Richard Szubin, Arjun Patel, Bernhard O. Palsson, Daniel C. Zielinski, Caroline M. Ajo-Franklin
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Engineered nucleocytosolic vehicles for loading of programmable editors Cell (IF 45.5) Pub Date : 2025-04-09 Julian Geilenkeuser, Niklas Armbrust, Emily Steinmaßl, Samuel W. Du, Sebastian Schmidt, Eva Maria Hildegard Binder, Yuchun Li, Niklas Wilhelm Warsing, Stephanie Victoria Wendel, Florian von der Linde, Elisa Marie Schiele, Xiya Niu, Luisa Stroppel, Oleksandr Berezin, Tobias Heinrich Santl, Tanja Orschmann, Keith Nelson, Christoph Gruber, Grazyna Palczewska, Carolline Rodrigues Menezes, Dong-Jiunn Jeffery
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Extensive N4 cytosine methylation is essential for Marchantia sperm function Cell (IF 45.5) Pub Date : 2025-04-09 James Walker, Jingyi Zhang, Yalin Liu, Shujuan Xu, Yiming Yu, Martin Vickers, Weizhi Ouyang, Judit Tálas, Liam Dolan, Keiji Nakajima, Xiaoqi Feng
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Autoimmune mechanisms elucidated through muscle acetylcholine receptor structures Cell (IF 45.5) Pub Date : 2025-04-08 Huanhuan Li, Minh C. Pham, Jinfeng Teng, Kevin C. O’Connor, Colleen M. Noviello, Ryan E. Hibbs
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Human proteome distribution atlas for tissue-specific plasma proteome dynamics Cell (IF 45.5) Pub Date : 2025-04-08 Erik Malmström, Lars Malmström, Simon Hauri, Tirthankar Mohanty, Aaron Scott, Christofer Karlsson, Carlos Gueto-Tettay, Emma Åhrman, Shahab Nozohoor, Bobby Tingstedt, Sara Regner, Peter Elfving, Leif Bjermer, Andreas Forsvall, Alexander Doyle, Mattias Magnusson, Ingrid Hedenfalk, Päivi Kannisto, Christian Brandt, Emma Nilsson, Johan Malmström
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Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals Cell (IF 45.5) Pub Date : 2025-04-08 Xuelong Mi, Alex Bo-Yuan Chen, Daniela Duarte, Erin Carey, Charlotte R. Taylor, Philipp N. Braaker, Mark Bright, Rafael G. Almeida, Jing-Xuan Lim, Virginia M.S. Ruetten, Yizhi Wang, Mengfan Wang, Weizhan Zhang, Wei Zheng, Michael E. Reitman, Yongkang Huang, Xiaoyu Wang, Lei Li, HanFei Deng, Song-Hai Shi, Guoqiang Yu
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Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage Cell (IF 45.5) Pub Date : 2025-04-08 Andrew Murley, Ann Catherine Popovici, Xiwen Sophie Hu, Anina Lund, Kevin Wickham, Jenni Durieux, Larry Joe, Etai Koronyo, Hanlin Zhang, Naomi R. Genuth, Andrew Dillin
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Brain-wide mapping of immune receptors uncovers a neuromodulatory role of IL-17E and the receptor IL-17RB Cell (IF 45.5) Pub Date : 2025-04-07 Yunjin Lee, Tomoe Ishikawa, Hyeseung Lee, Byeongjun Lee, Changhyeon Ryu, Irene Davila Mejia, Minjin Kim, Guangqing Lu, Yujin Hong, Mengyang Feng, Hyeyoon Shin, Sylvain Meloche, Richard M. Locksley, Ekaterina Koltsova, Sergei I. Grivennikov, Myriam Heiman, Gloria B. Choi, Jun R. Huh
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Peripheral nervous system microglia-like cells regulate neuronal soma size throughout evolution Cell (IF 45.5) Pub Date : 2025-04-07 Zhisheng Wu, Yiheng Wang, Wei-wei Chen, Hua Sun, Xiaoyan Chen, Xiaobo Li, Zeshuai Wang, Weizheng Liang, Shuang-Yin Wang, Xuemei Luan, Yijiang Li, Shangjin Huang, Yuteng Liang, Jiaqi Zhang, Zhou-Feng Chen, Guanlin Wang, Yun Gao, Yanan Liu, Jun Wang, Zhen Liu, Peng Shi, Cirong Liu, Longbao Lv, Anli Hou, Chenglin Wu, Chen Yao, Zexuan Hong, Ji Dai, Zhonghua Lu, Fan Pan, Xin Chen, Helmut Kettenmann, Ido
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Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety Cell (IF 45.5) Pub Date : 2025-04-07 Byeongjun Lee, Jeong-Tae Kwon, Yire Jeong, Hannah Caris, Dongsun Oh, Mengyang Feng, Irene Davila Mejia, Xiaoying Zhang, Tomoe Ishikawa, Brianna R. Watson, Jeffrey R. Moffitt, Kwanghun Chung, Jun R. Huh, Gloria B. Choi
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Channel synapse mediates neurotransmission of airway protective chemoreflexes Cell (IF 45.5) Pub Date : 2025-04-04 Shogo Soma, Norihito Hayatsu, Kengo Nomura, Mark W. Sherwood, Tatsuro Murakami, Yoichiro Sugiyama, Naofumi Suematsu, Takanori Aoki, Yu Yamada, Moe Asayama, Mami Kaneko, Kento Ohbayashi, Misa Arizono, Masato Ohtsuka, Shun Hamada, Ichiro Matsumoto, Yusaku Iwasaki, Nobuhiko Ohno, Yasushi Okazaki, Akiyuki Taruno
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Molecular basis for shifted receptor recognition by an encephalitic arbovirus Cell (IF 45.5) Pub Date : 2025-04-04
Western equine encephalitis virus (WEEV) is an arbovirus that historically caused large outbreaks of encephalitis throughout the Americas. WEEV binds …
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Structural basis for plasticity in receptor engagement by an encephalitic alphavirus Cell (IF 45.5) Pub Date : 2025-04-04 Saravanan Raju, Sathvik Palakurty, Alan Sariol, Ngan Wagoner, Lucas J. Adams, Sean Hui, William B. Klimstra, Daved H. Fremont, Michael S. Diamond
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Conserved genetic basis for microbial colonization of the gut Cell (IF 45.5) Pub Date : 2025-04-04 Menghan Liu, Sydney B. Blattman, Mai Takahashi, Nandan Mandayam, Wenyan Jiang, Panos Oikonomou, Sohail F. Tavazoie, Saeed Tavazoie
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PAX translocations remodel mitochondrial metabolism through altered leucine usage in rhabdomyosarcoma Cell (IF 45.5) Pub Date : 2025-04-03 Bhargab Kalita, Gerard Martinez-Cebrian, Justina McEvoy, Melody Allensworth, Michelle Knight, Alessandro Magli, Rita C.R. Perlingeiro, Michael A. Dyer, Elizabeth Stewart, Brian David Dynlacht
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Rorγt-positive dendritic cells are required for the induction of peripheral regulatory T cells in response to oral antigens Cell (IF 45.5) Pub Date : 2025-04-03 Patrick Fernandes Rodrigues, Shitong Wu, Tihana Trsan, Santosh K. Panda, José Luís Fachi, Yizhou Liu, Siling Du, Sarah de Oliveira, Alina Ulezko Antonova, Darya Khantakova, Raki Sudan, Pritesh Desai, Michael S. Diamond, Susan Gilfillan, Stephen K. Anderson, Marina Cella, Marco Colonna
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Single-cell spatial transcriptome atlas and whole-brain connectivity of the macaque claustrum Cell (IF 45.5) Pub Date : 2025-04-03 Ying Lei, Yuxuan Liu, Mingli Wang, Nini Yuan, Yujie Hou, Lingjun Ding, Zhiyong Zhu, Zihan Wu, Chao Li, Mingyuan Zheng, Ruiyi Zhang, Ana Rita Ribeiro Gomes, Yuanfang Xu, Zhaoke Luo, Zhen Liu, Qinwen Chai, Pierre Misery, Yanqing Zhong, Xinxiang Song, Camille Lamy, Zhiming Shen
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20 years of histone lysine demethylases: From discovery to the clinic and beyond Cell (IF 45.5) Pub Date : 2025-04-03 Zach H. Gray, Madison A. Honer, Pooja Ghatalia, Yang Shi, Johnathan R. Whetstine
Twenty years ago, histone lysine demethylases (KDMs) were discovered. Since their discovery, they have been increasingly studied and shown to be important across species, development, and diseases. Considerable advances have been made toward understanding their (1) enzymology, (2) role as critical components of biological complexes, (3) role in normal cellular processes and functions, (4) implications
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Cell membranes sustain phospholipid imbalance via cholesterol asymmetry Cell (IF 45.5) Pub Date : 2025-04-02 Milka Doktorova, Jessica L. Symons, Xiaoxuan Zhang, Hong-Yin Wang, Jan Schlegel, Joseph H. Lorent, Frederick A. Heberle, Erdinc Sezgin, Edward Lyman, Kandice R. Levental, Ilya Levental
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Therapeutic potential of allosteric HECT E3 ligase inhibition Cell (IF 45.5) Pub Date : 2025-04-02 Alexander M.K. Rothman, Amir Florentin, Florence Zink, Catherine Quigley, Olivier Bonneau, Rene Hemmig, Amanda Hachey, Tomas Rejtar, Maulik Thaker, Rishi Jain, Shih-Min Huang, Daniel Sutton, Jan Roger, Ji-Hu Zhang, Sven Weiler, Simona Cotesta, Johannes Ottl, Salil Srivastava, Alina Kordonsky, Reut Avishid, David J. Rowlands
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Genetically encoded reporters of actin filament organization in living cells and tissues Cell (IF 45.5) Pub Date : 2025-04-02 Carla Silva Martins, François Iv, Shashi Kumar Suman, Thomas C. Panagiotou, Clara Sidor, María Ruso-López, Camille N. Plancke, Shizue Omi, Rebecca Pagès, Maxime Gomes, Alexander Llewellyn, Sourish Reddy Bandi, Laurie Ramond, Federica Arbizzani, Caio Vaz Rimoli, Frank Schnorrer, François Robin, Andrew Wilde, Loïc LeGoff, Jean-Denis Pedelacq, Manos Mavrakis
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Engineering sonogenetic EchoBack-CAR T cells Cell (IF 45.5) Pub Date : 2025-04-02 Longwei Liu, Peixiang He, Yuxuan Wang, Fengyi Ma, Dulei Li, Zhiliang Bai, Yunjia Qu, Linshan Zhu, Chi Woo Yoon, Xi Yu, Yixuan Huang, Zhengyu Liang, Yiming Zhang, Kunshu Liu, Tianze Guo, Yushun Zeng, Qifa Zhou, H. Kay Chung, Rong Fan, Yingxiao Wang
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A chemical radar allows bacteria to detect and kill predators Cell (IF 45.5) Pub Date : 2025-04-02 Shuaibing Zhang, Kevin Schlabach, Victor Hugo Pérez Carrillo, Anan Ibrahim, Shahran Nayem, Anna Komor, Ruchira Mukherji, Somak Chowdhury, Lisa Reimer, Felix Trottmann, A. Corina Vlot, Christian Hertweck, Ute A. Hellmich, Pierre Stallforth
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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease Cell (IF 45.5) Pub Date : 2025-03-31 Yiwen Hou, Yue Wu, Yang Cao, Xiaoxia Hu, Yuqian Sun, Hongmei Wang, Liang Wang, Jialin Zhou, Zhonglin Zhang, Zhiwei Liu, Baolin Tang, Kaidi Song, Guangyu Sun, Wen Gao, Tianqi Zheng, Ping Wu, Weiwei Wu, Dapeng Ju, Xiaoyu Zhu, Cheng Zhan
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Global analysis of protein turnover dynamics in single cells Cell (IF 45.5) Pub Date : 2025-03-31 Pierre Sabatier, Maico Lechner, Ulises H. Guzmán, Christian M. Beusch, Xinlei Zeng, Longteng Wang, Fabiana Izaguirre, Anjali Seth, Olga Gritsenko, Sergey Rodin, Karl-Henrik Grinnemo, Zilu Ye, Jesper V. Olsen
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Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic Cell (IF 45.5) Pub Date : 2025-03-31 Frank Bürmann, Bryony Clifton, Sophie Koekemoer, Oliver J. Wilkinson, Dari Kimanius, Mark S. Dillingham, Jan Löwe
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A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer Cell (IF 45.5) Pub Date : 2025-03-26 Zedao Liu, Zhenlin Yang, Junqi Wu, Wenjie Zhang, Yuxuan Sun, Chao Zhang, Guangyu Bai, Li Yang, Hongtao Fan, Yawen Chen, Lei Zhang, Benyuan Jiang, Xiaoyan Liu, Xiaoshi Ma, Wei Tang, Chang Liu, Yang Qu, Lixu Yan, Deping Zhao, Yilong Wu, Zemin Zhang
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Large language models deconstruct the clinical intuition behind diagnosing autism Cell (IF 45.5) Pub Date : 2025-03-26 Jack Stanley, Emmett Rabot, Siva Reddy, Eugene Belilovsky, Laurent Mottron, Danilo Bzdok
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Enteric neuronal Piezo1 maintains mechanical and immunological homeostasis by sensing force Cell (IF 45.5) Pub Date : 2025-03-24 Zili Xie, Lillian Rose, Jing Feng, Yonghui Zhao, Yisi Lu, Harry Kane, Timothy J. Hibberd, Xueming Hu, Zhen Wang, Kaikai Zang, Xingliang Yang, Quentin Richardson, Rahmeh Othman, Olivia Venezia, Ademi Zhakyp, Fang Gao, Nobuya Abe, Keren Vigeland, Hongshen Wang, Camren Branch, Ruaidhrí Jackson
更新日期：2025-04-24
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