Climate change may amplify the frequency and severity of supply-demand mismatches in future power systems with high shares of wind and solar energy1,2. Here, we use a dispatch optimization model to assess potential increases in hourly costs associated with such climate-intensified gaps under fixed, high penetrations of wind and solar generation. We further explore various strategies to enhance system

Long (>200 nucleotides) non-coding RNAs (lncRNAs) play important roles in diverse aspects of life. Over 20 classes of lncRNAs have been identified in bacteria and bacteriophages through comparative genomics analyses, but their biological functions remain largely unexplored1-3. Due to the large sizes, the structural determinants of most lncRNAs also remain uncharacterized. Here we report the structures

Young exoplanets provide a critical link between understanding planet formation and atmospheric evolution1. Direct imaging spectroscopy allows us to infer the properties of young, wide orbit, giant planets with high signal-to-noise. This allows us to compare this young population to exoplanets characterized with transmission spectroscopy, which has indirectly revealed the presence of clouds2-4, photochemistry5

Plasma membrane integrity is vital for nearly all aspects of cell functioning1. Mechanical forces can cause plasma membrane damage2, but it is not known whether there are large molecules that regulate plasma membrane integrity under mechanical strain. Here we constructed a 384-well cellular stretch system that delivers precise, reproducible strain to cultured cells. Using the system, we screened 10