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Blockade of endothelin receptors mitigates SARS-CoV-2-induced osteoarthritis Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-11 Man Ting Au, Junguo Ni, Kaiming Tang, Wei Wang, Lanlan Zhang, Hantang Wang, Fangyi Zhao, Zhan Li, Peng Luo, Lawrence Chun-Man Lau, Ping-Keung Chan, Cuiting Luo, Bo Zhou, Lin Zhu, Charlie Yuli Zhang, Tianshu Jiang, Marianne Lauwers, Jasper Fuk-Woo Chan, Shuofeng Yuan, Chunyi Wen
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Primary succession of Bifidobacteria drives pathogen resistance in neonatal microbiota assembly Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-06 Yan Shao, Cristina Garcia-Mauriño, Simon Clare, Nicholas J. R. Dawson, Andre Mu, Anne Adoum, Katherine Harcourt, Junyan Liu, Hilary P. Browne, Mark D. Stares, Alison Rodger, Peter Brocklehurst, Nigel Field, Trevor D. Lawley
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An intranuclear bacterial parasite of deep-sea mussels expresses apoptosis inhibitors acquired from its host Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-06 Miguel Ángel González Porras, Adrien Assié, Målin Tietjen, Marlene Violette, Manuel Kleiner, Harald Gruber-Vodicka, Nicole Dubilier, Nikolaus Leisch
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Continental-scale associations of Arabidopsis thaliana phyllosphere members with host genotype and drought Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-06 Talia L. Karasov, Manuela Neumann, Laura Leventhal, Efthymia Symeonidi, Gautam Shirsekar, Aubrey Hawks, Grey Monroe, Moisés Exposito-Alonso, Joy Bergelson, Detlef Weigel, Rebecca Schwab
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Mycobacterium tuberculosis virulence lipid PDIM inhibits autophagy in mice Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-06 Ekansh Mittal, G. V. R. Krishna Prasad, Sandeep Upadhyay, Jully Sadadiwala, Andrew J. Olive, Guozhe Yang, Christopher M. Sassetti, Jennifer A. Philips
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Diverse RNA viruses of parasitic nematodes can elicit antibody responses in vertebrate hosts Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-04 Shannon Quek, Amber Hadermann, Yang Wu, Lander De Coninck, Shrilakshmi Hegde, Jordan R. Boucher, Jessica Cresswell, Ella Foreman, Andrew Steven, E. James LaCourse, Stephen A. Ward, Samuel Wanji, Grant L. Hughes, Edward I. Patterson, Simon C. Wagstaff, Joseph D. Turner, Rhys H. Parry, Alain Kohl, Eva Heinz, Kenneth Bentum Otabil, Jelle Matthijnssens, Robert Colebunders, Mark J. Taylor
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Discovery of CO2 tolerance genes associated with virulence in the fungal pathogen Cryptococcus neoformans Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-04 Benjamin J. Chadwick, Laura C. Ristow, Xiaofeng Xie, Damian J. Krysan, Xiaorong Lin
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We must learn from past outbreaks Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-03
To successfully tackle the current mpox public-health emergency, we must learn from past outbreaks to focus research questions and take collaborative action.
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Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-03 Xin Zhou, Audrey Hilk, Norma V. Solis, Nancy Scott, Annette Beach, Natthapon Soisangwan, Clara L. Billings, Laura S. Burrack, Scott G. Filler, Anna Selmecki
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Individual bacterial cells can use spatial sensing of chemical gradients to direct chemotaxis on surfaces Nat. Microbiol. (IF 20.5) Pub Date : 2024-09-02 James H. R. Wheeler, Kevin R. Foster, William M. Durham
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Neurospora intermedia from a traditional fermented food enables waste-to-food conversion Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-29 Vayu Maini Rekdal, José Manuel Villalobos-Escobedo, Nabila Rodriguez-Valeron, Mikel Olaizola Garcia, Diego Prado Vásquez, Alexander Rosales, Pia M. Sörensen, Edward E. K. Baidoo, Ana Calheiros de Carvalho, Robert Riley, Anna Lipzen, Guifen He, Mi Yan, Sajeet Haridas, Christopher Daum, Yuko Yoshinaga, Vivian Ng, Igor V. Grigoriev, Rasmus Munk, Christofora Hanny Wijaya, Lilis Nuraida, Isty Damayanti
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Understanding emerging and re-emerging viruses to facilitate pandemic preparedness Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-28 Francisco J. Zapatero-Belinchón, Priti Kumar, Melanie Ott, Olivier Schwartz, Alex Sigal
On 8–11 April 2024, a Keystone meeting on human immunodeficiency virus and emerging and re-emerging viruses convened in Hannover, Germany, aiming to unite researchers studying viruses of global concern, and gain a deep understanding of unique and shared viral disease mechanisms to facilitate pandemic preparedness.
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An S-methyltransferase that produces the climate-active gas dimethylsulfide is widespread across diverse marine bacteria Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-28 Yunhui Zhang, Chuang Sun, Zihua Guo, Liyan Liu, Xiaotong Zhang, Kai Sun, Yanfen Zheng, Andrew J. Gates, Jonathan D. Todd, Xiao-Hua Zhang
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Aspergillus fumigatus conidial surface-associated proteome reveals factors for fungal evasion and host immunity modulation Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-27 Camila Figueiredo Pinzan, Clara Valero, Patrícia Alves de Castro, Jefferson Luiz da Silva, Kayleigh Earle, Hong Liu, Maria Augusta Crivelente Horta, Olaf Kniemeyer, Thomas Krüger, Annica Pschibul, Derya Nur Cömert, Thorsten Heinekamp, Axel A. Brakhage, Jacob L. Steenwyk, Matthew E. Mead, Nico Hermsdorf, Scott G. Filler, Nathalia Gonsales da Rosa-Garzon, Endrews Delbaje, Michael J. Bromley, Hamilton
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Manipulation of host phagocytosis by fungal pathogens and therapeutic opportunities Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-26 Lei-Jie Jia, Katherine González, Thomas Orasch, Franziska Schmidt, Axel A. Brakhage
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Evolution of SARS-CoV-2 in the murine central nervous system drives viral diversification Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-23 Jacob Class, Lacy M. Simons, Ramon Lorenzo-Redondo, Jazmin Galván Achi, Laura Cooper, Tanushree Dangi, Pablo Penaloza-MacMaster, Egon A. Ozer, Sarah E. Lutz, Lijun Rong, Judd F. Hultquist, Justin M. Richner
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Fc-engineered antibodies promote neutrophil-dependent control of Mycobacterium tuberculosis Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-22 Edward B. Irvine, Angel Nikolov, Mehak Z. Khan, Joshua M. Peters, Richard Lu, Jaimie Sixsmith, Aaron Wallace, Esther van Woudenbergh, Sally Shin, Wiktor Karpinski, Jeff C. Hsiao, Arturo Casadevall, Bryan D. Bryson, Lisa Cavacini, Patricia S. Grace, Galit Alter, Sarah M. Fortune
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Bacteria induce metabolic perturbations in ticks Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-21 W. Robert Shaw, Flaminia Catteruccia
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The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-21 Lu Zhang, Xiao-Xu Leng, Jianxun Qi, Ni Wang, Ji-Xuan Han, Zhi-Hang Tao, Zi-Yan Zhuang, Yimeng Ren, Yi-Le Xie, Shan-Shan Jiang, Jia-Lu Li, Huimin Chen, Cheng-Bei Zhou, Yun Cui, Xiaoyu Chen, Zheng Wang, Zi-Zhen Zhang, Jie Hong, Hao-Yan Chen, Weihong Jiang, Ying-Xuan Chen, Xin Zhao, Jun Yu, Jing-Yuan Fang
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Gut epithelial electrical cues drive differential localization of enterobacteria Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-20 Yaohui Sun, Fernando Ferreira, Brian Reid, Kan Zhu, Li Ma, Briana M. Young, Catherine E. Hagan, Renée M. Tsolis, Alex Mogilner, Min Zhao
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Host–gut microbiota crosstalk predicts neuroinflammation Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-19 Carolina M. Polonio, Francisco J. Quintana
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Non-canonical start codons confer context-dependent advantages in carbohydrate utilization for commensal E. coli in the murine gut Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-19 Yassine Cherrak, Miguel Angel Salazar, Nicolas Näpflin, Lukas Malfertheiner, Mathias K.-M. Herzog, Christopher Schubert, Christian von Mering, Wolf-Dietrich Hardt
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Translating between science and politics as a government adviser Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-16 Robin C. May
Moving from academia to government was challenging, but learning to translate evidence-based results into policy decisions that impact society is hugely rewarding, writes Robin May.
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Evolutionary origin of the tropical race 4 banana pathogen and mechanisms of its virulence Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-16
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Virulence of banana wilt-causing fungal pathogen Fusarium oxysporum tropical race 4 is mediated by nitric oxide biosynthesis and accessory genes Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-16 Yong Zhang, Siwen Liu, Diane Mostert, Houlin Yu, Mengxia Zhuo, Gengtan Li, Cunwu Zuo, Sajeet Haridas, Katie Webster, Minhui Li, Igor V. Grigoriev, Ganjun Yi, Altus Viljoen, Chunyu Li, Li-Jun Ma
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Bacteria modulate microalgal aging physiology through the induction of extracellular vesicle production to remove harmful metabolites Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-14 Yun Deng, Ruyi Yu, Veit Grabe, Thomas Sommermann, Markus Werner, Marine Vallet, Christian Zerfaß, Oliver Werz, Georg Pohnert
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Staphylococcus aureus adapts to exploit collagen-derived proline during chronic infection Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-12 Andreacarola Urso, Ian R. Monk, Ying-Tsun Cheng, Camilla Predella, Tania Wong Fok Lung, Erin M. Theiller, Jack Boylan, Sofya Perelman, Swikrity U. Baskota, Ahmed M. Moustafa, Gaurav Lohia, Ian A. Lewis, Benjamin P. Howden, Timothy P. Stinear, Nicolino V. Dorrello, Victor Torres, Alice S. Prince
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Darwin’s expedition revisited to reveal the evolution of plant–microbe interactions on Galápagos Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-06 Viviane Cordovez, Víctor J. Carrión, Gonzalo Rivas Torres, Diego A. Ortiz, Wilson Cabrera, Haig Balian, Adriana Karina Vivanco, Juan E. Pérez-Jaramillo, Jaime Chaves, Diana A. Pazmiño, Pieter van ’t Hof, Jos M. Raaijmakers
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Quantitative principles of microbial metabolism shared across scales Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-06 Daniel Sher, Daniel Segrè, Michael J. Follows
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Microscopy methods map mobile genetic elements and their bacterial hosts Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-05
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Aspergillus cvjetkovicii protects against phytopathogens through interspecies chemical signalling in the phyllosphere Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-05 Xiaoyan Fan, Haruna Matsumoto, Haorong Xu, Hongda Fang, Qianqian Pan, Tianxing Lv, Chengfang Zhan, Xiaoxiao Feng, Xiaoyu Liu, Danrui Su, Mengyuan Fan, Zhonghua Ma, Gabriele Berg, Shaojia Li, Tomislav Cernava, Mengcen Wang
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Angiopoietin-like 4 protects against endothelial dysfunction during bacterial sepsis Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-05 Jason Ziveri, Loïc Le Guennec, Isabel dos Santos Souza, Jean-Philipe Barnier, Samuel M. Walter, Youssouf Diallo, Yasmine Smail, Elodie Le Seac’h, Haniaa Bouzinba-Segard, Camille Faure, Philippe C. Morand, Irié Carel, Nicolas Perriere, Taliah Schmitt, Brigitte Izac, Franck Letourneur, Mathieu Coureuil, Thomas Rattei, Xavier Nassif, Sandrine Bourdoulous
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The evolving landscape of live attenuated COVID-19 vaccines Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-02 Simone Pecetta, Rino Rappuoli
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Shining light on the coral photosymbiont family Symbiodiniaceae Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-02 Madeleine J. H. van Oppen
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Bringing microbial ecology into focus Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-02
This month’s issue of Nature Microbiology has a focus on microbial ecology, showcasing how these dynamics might be harnessed to better understand and safeguard life on Earth.
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Host-imposed control mechanisms in legume–rhizobia symbiosis Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-02 Stephanie S. Porter, Simon E. Dupin, R. Ford Denison, E. Toby Kiers, Joel L. Sachs
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Integrating viruses into soil food web biogeochemistry Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-02 Cátia Carreira, Christian Lønborg, Basistha Acharya, Laxman Aryal, Zivile Buivydaite, Felipe Borim Corrêa, Tingting Chen, Christine Lorenzen Elberg, Joanne B. Emerson, Luke Hillary, Ram B. Khadka, Valérie Langlois, Kyle Mason-Jones, Tarquin Netherway, Suvi Sutela, Gareth Trubl, Arno wa Kang’eri, Ruiqi Wang, Richard Allen White, Anne Winding, Tianci Zhao, Rumakanta Sapkota
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Differential rates of Mycobacterium tuberculosis transmission associate with host–pathogen sympatry Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-01 Matthias I. Gröschel, Francy J. Pérez-Llanos, Roland Diel, Roger Vargas, Vincent Escuyer, Kimberlee Musser, Lisa Trieu, Jeanne Sullivan Meissner, Jillian Knorr, Don Klinkenberg, Peter Kouw, Susanne Homolka, Wojciech Samek, Barun Mathema, Dick van Soolingen, Stefan Niemann, Shama Desai Ahuja, Maha R. Farhat
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An acidophilic fungus promotes prey digestion in a carnivorous plant Nat. Microbiol. (IF 20.5) Pub Date : 2024-08-01 Pei-Feng Sun, Min R. Lu, Yu-Ching Liu, Brandon J. P. Shaw, Chieh-Ping Lin, Hung-Wei Chen, Yu-fei Lin, Daphne Z. Hoh, Huei-Mien Ke, I-Fan Wang, Mei-Yeh Jade Lu, Erica B. Young, Jonathan Millett, Roland Kirschner, Ying-Chung Jimmy Lin, Ying-Lan Chen, Isheng Jason Tsai
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Harnessing a brain parasite as a tool for delivery of therapeutics to the brain Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-29
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Engineering Toxoplasma gondii secretion systems for intracellular delivery of multiple large therapeutic proteins to neurons Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-29 Shahar Bracha, Hannah J. Johnson, Nicole A. Pranckevicius, Francesca Catto, Athena E. Economides, Sergey Litvinov, Karoliina Hassi, Marco Tullio Rigoli, Cristina Cheroni, Matteo Bonfanti, Alessia Valenti, Sarah Stucchi, Shruti Attreya, Paul D. Ross, Daniel Walsh, Nati Malachi, Hagay Livne, Reut Eshel, Vladislav Krupalnik, Doron Levin, Stuart Cobb, Petros Koumoutsakos, Nicolò Caporale, Giuseppe Testa
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SARS-CoV-2-related bat viruses evade human intrinsic immunity but lack efficient transmission capacity Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-29 Mario A. Peña-Hernández, Mia Madel Alfajaro, Renata B. Filler, Miyu Moriyama, Emma L. Keeler, Zara E. Ranglin, Yong Kong, Tianyang Mao, Bridget L. Menasche, Madeleine C. Mankowski, Zhe Zhao, Chantal B. F. Vogels, Anne M. Hahn, Chaney C. Kalinich, Shuo Zhang, Nicholas Huston, Han Wan, Rafael Araujo-Tavares, Brett D. Lindenbach, Robert Homer, Anna Marie Pyle, David R. Martinez, Nathan D. Grubaugh, Benjamin
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CRISPRi–TnSeq maps genome-wide interactions between essential and non-essential genes in bacteria Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-19 Bimal Jana, Xue Liu, Julien Dénéréaz, Hongshik Park, Dmitry Leshchiner, Bruce Liu, Clément Gallay, Junhao Zhu, Jan-Willem Veening, Tim van Opijnen
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Gut microbial factors predict disease severity in a mouse model of multiple sclerosis Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-15 Alex Steimle, Mareike Neumann, Erica T. Grant, Stéphanie Willieme, Alessandro De Sciscio, Amy Parrish, Markus Ollert, Eiji Miyauchi, Tomoyoshi Soga, Shinji Fukuda, Hiroshi Ohno, Mahesh S. Desai
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MHC class II proteins mediate sialic acid independent entry of human and avian H2N2 influenza A viruses Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-15 Umut Karakus, Milagros Sempere Borau, Patricia Martínez-Barragán, Josephine von Kempis, Soner Yildiz, Laura M. Arroyo-Fernández, Marie O. Pohl, Julia A. Steiger, Irina Glas, Annika Hunziker, Adolfo García-Sastre, Silke Stertz
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A dynamic subpopulation of CRISPR–Cas overexpressers allows Streptococcus pyogenes to rapidly respond to phage Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-12 Marie J. Stoltzfus, Rachael E. Workman, Nicholas C. Keith, Joshua W. Modell
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A safe, effective and adaptable live-attenuated SARS-CoV-2 vaccine to reduce disease and transmission using one-to-stop genome modifications Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-12 Jacob Schön, G. Tuba Barut, Bettina Salome Trüeb, Nico Joel Halwe, Inês Berenguer Veiga, Annika Kratzel, Lorenz Ulrich, Jenna N. Kelly, Melanie Brügger, Claudia Wylezich, Adriano Taddeo, Etori Aguiar Moreira, Demeter Túrós, Llorenç Grau-Roma, Ann Kathrin Ahrens, Kore Schlottau, Tobias Britzke, Angele Breithaupt, Björn Corleis, Jana Kochmann, Blandina I. Oliveira Esteves, Lea Almeida, Lisa Thomann,
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Bacterial reprogramming of tick metabolism impacts vector fitness and susceptibility to infection Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-12 Sourabh Samaddar, Agustin Rolandelli, Anya J. O’Neal, Hanna J. Laukaitis-Yousey, Liron Marnin, Nisha Singh, Xiaowei Wang, L. Rainer Butler, Parisa Rangghran, Chrysoula Kitsou, Francy E. Cabrera Paz, Luisa Valencia, Camila R. Ferraz, Ulrike G. Munderloh, Benedict Khoo, Benjamin Cull, Kristin L. Rosche, Dana K. Shaw, Jonathan Oliver, Sukanya Narasimhan, Erol Fikrig, Utpal Pal, Gary M. Fiskum, Brian M
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Multikingdom and functional gut microbiota markers for autism spectrum disorder Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-08 Qi Su, Oscar W. H. Wong, Wenqi Lu, Yating Wan, Lin Zhang, Wenye Xu, Moses K. T. Li, Chengyu Liu, Chun Pan Cheung, Jessica Y. L. Ching, Pui Kuan Cheong, Ting Fan Leung, Sandra Chan, Patrick Leung, Francis K. L. Chan, Siew C. Ng
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CRISPR-based functional profiling of the Toxoplasma gondii genome during acute murine infection Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-08 Christopher J. Giuliano, Kenneth J. Wei, Faye M. Harling, Benjamin S. Waldman, Madeline A. Farringer, Elizabeth A. Boydston, Tammy C. T. Lan, Raina W. Thomas, Alice L. Herneisen, Allen G. Sanderlin, Isabelle Coppens, Jeffrey D. Dvorin, Sebastian Lourido
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Environmentally dependent interactions shape patterns in gene content across natural microbiomes Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-08 Kyle Crocker, Kiseok Keith Lee, Milena Chakraverti-Wuerthwein, Zeqian Li, Mikhail Tikhonov, Madhav Mani, Karna Gowda, Seppe Kuehn
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Algal methylated compounds shorten the lag phase of Phaeobacter inhibens bacteria Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-05 Martin Sperfeld, Delia A. Narváez-Barragán, Sergey Malitsky, Veronica Frydman, Lilach Yuda, Jorge Rocha, Einat Segev
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Enterococcus faecalis-derived adenine enhances enterohaemorrhagic Escherichia coli Type 3 Secretion System-dependent virulence Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-04 Fernando H. Martins, Thibaut Rosay, Anubama Rajan, Hannah E. Carter, Tayah Turocy, Andres Mejia, Jason M. Crawford, Anthony W. Maresso, Vanessa Sperandio
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Using gene copy flexibility to build adaptable synthetic microbial populations Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-03
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Loving mucus with Akkermansia muciniphila Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-03 Lauren Davey
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Moving from hype to hope in diet–microbiome interactions Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-03
To mark World Microbiome Day, we reflect on recent developments in gut microbiome and diet research, including the complexities of this rapidly evolving field and future opportunities.
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Body heat drives antifungal resistance Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-03 Michael J. Bottery, David W. Denning
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Glutathione-mediated redox regulation in Cryptococcus neoformans impacts virulence Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-02 Braydon Black, Leandro Buffoni Roque da Silva, Guanggan Hu, Xianya Qu, Daniel F. Q. Smith, Armando Alcázar Magaña, Linda C. Horianopoulos, Mélissa Caza, Rodgoun Attarian, Leonard J. Foster, Arturo Casadevall, James W. Kronstad
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Microbes produce biofilms to support their communities in nutrient-limited environments Nat. Microbiol. (IF 20.5) Pub Date : 2024-07-01 Isis Del Mazo-Monsalvo, Michel Geovanni Santiago-Martínez
Biofilms are complex extracellular structures formed by microbes (bacteria, archaea, protists, fungi and microalgae), usually as a response to stress induced by fluctuating factors in their environment1. However, microbes also naturally form biofilms to facilitate their interactions with other microbes, their environment and their hosts. Biofilms are generally composed of extracellular DNA, complex