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Rethinking the burden of latent tuberculosis to reprioritize research

Analyses refuting the dogma that a quarter of the world’s population is latently infected with Mycobacterium tuberculosis emphasize the need for a redirection of research priorities.

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Fig. 1: Models of TB pathogenesis and disease progression.

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Acknowledgements

M.A.B. is supported by a Tier 1 Canada Research Chair from the Canadian Institutes for Health Research. L.R. is supported by a Principal Research Fellowship from the Wellcome Trust and a Research Project Grant (RO1) from the National Institutes of Health.

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Correspondence to Lalita Ramakrishnan.

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Nature Microbiology thanks Brian Robertson and the other, anonymous, reviewer(s) for their contribution to the peer review of this work.

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Behr, M.A., Edelstein, P.H. & Ramakrishnan, L. Rethinking the burden of latent tuberculosis to reprioritize research. Nat Microbiol (2024). https://doi.org/10.1038/s41564-024-01683-0

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