First discovered more than five decades ago, protein ubiquitylation has proven to be an omnipresent post-translational modification regulating virtually every eukaryotic cellular process. With novel clinical applications and recent studies demonstrating ubiquitylation of biomolecules other than proteins, the interest in ubiquitin will not waver any time soon.

中文翻译：

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加深对泛素化的理解

蛋白质泛素化在五十多年前首次被发现，已被证明是一种无所不在的翻译后修饰，几乎调节每个真核细胞过程。随着新的临床应用和最近的研究证明蛋白质以外的生物分子泛素化，人们对泛素的兴趣不会很快动摇。