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In Memoriam: William (Bill) R. Yates, MD, and Russell (Russ) Noyes, MD. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Donald W Black
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Development of a mobile monitoring program for anxiety and depression in pregnancy and evaluation of 3-month results. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Yavuz Selim Oğur,Esra Yazıcı,Hilal Uslu Yuvacı,Nur Banu Oğur,Elif Köse,Ahmet Bülent Yazıcı
BACKGROUND The aims of this study were to develop a mobile mental health application (app) to scan the symptoms of anxiety, depression, and related factors during pregnancy; examine the effect of the app on pregnant women; and determine the factors related to using such an app. METHODS A software platform called Perinatal Anxiety Depression Monitoring Platform (PADIP) was developed. This study included
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Vitamin D levels among adult psychiatric inpatients and the association with psychosis. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Hossam Guirgis,Anne-Marie Duchemin,Sophia Vargo,Nagy A Youssef
BACKGROUND The association between low vitamin D levels and mental illness has been described in earlier research. The aim of our study was to examine the association between vitamin D levels with psychotic symptoms among hospitalized patients. METHODS A total of 1,456 patient records from an academic psychiatric hospital were examined. Vitamin D levels were classified as normal (>30 ng/mL); insufficient
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The role of psychiatry in bariatric care. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Richard Balon
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Protest behaviors among patients placed in seclusion in a psychiatric emergency service. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Tyler Q Ruch,Chelsea Hoops,Rif S El-Mallakh,Christina Terrell
BACKGROUND Patients placed in seclusion for behavioral dyscontrol often perceive that the health care team is treating them inappropriately. These patients may express their indignation in many ways. To better characterize these behaviors, we conducted a study of protest behaviors in a psychiatric emergency service. METHODS Video surveillance of seclusion room occupants is routinely reviewed as part
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Same but different? Phenomenological differences among various types of body-focused repetitive behaviors. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Steffen Moritz,Danielle Penney,Franziska Mißmann,Ivar Snorrason,Stella Schmotz
BACKGROUND Body-focused repetitive behaviors (BFRBs) are highly prevalent conditions at the border of psychiatry and dermatology. Using a newly developed scale, the Generic BFRB scale (GBS-36), we aimed to compare 4 prominent BFRBs in terms of phenomenology, age at onset, and other illness-related aspects. METHODS A sample of 391 individuals with different forms of BFRBs completed the GBS-36, the Patient
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Problematic internet use and suicidal behavior in adolescents: A review. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Edith Jolin,Ronald Weller
BACKGROUND Suicide is a leading cause of death in adolescents. Problematic internet use (PIU) has been associated with suicidal behavior in this age group. To assess this association, we reviewed population-based studies that examined the relationship between PIU and suicidal behavior. METHODS We searched PubMed, PsycINFO, and Web of Science for studies published in English from 1995 through 2021.
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Posttraumatic stress disorder comorbidity in patients undergoing ECT for major depressive disorder. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-11-01 Nagy A Youssef,Leon Brodsky,Rikinkumar S Patel
BACKGROUND Posttraumatic stress disorder (PTSD) is not recognized as an indication for electroconvulsive therapy (ECT). However, research indicates promise for this treatment modality. To elucidate the effects of ECT for treating PTSD, prospective research is needed. The first step in assessing the feasibility of such research is to determine if many patients being treated with ECT have comorbid PTSD
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Differences in clinical presentations of patients seeking care for treatment-resistant depression across sexual orientations and gender identities. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Isabel Benjamin,Rachel Hershenberg,Kate D Dorrell,Amanda C Tan,Patricio Riva-Posse,William M McDonald,Adriana P Hermida,Andrea Crowell,Brian A Feinstein
BACKGROUND Sexual and/or gender minority (SGM) individuals experience higher rates and greater severity of depressive disorders than non-SGM persons. SGM individuals are more likely than non-SGM individuals to seek mental health treatment and to present to treatment with unique characteristics that should be accounted for when considering treatment recommendations. Patients seeking care for treatment-resistant
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Characteristics and experiences of professionals providing 9/11 mental health services. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Carol S North,Samina Mahesar,Karen J Meltzer,David E Pollio
BACKGROUND After disasters, mental health professionals might be called upon to help address the emotional consequences of the disaster among survivors and other affected groups, but the clinicians themselves could be affected. This exploratory study examined the experiences of 60 mental health professionals, most of whom provided mental health care to individuals affected by the September 11, 2001
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High-dose armodafinil in treatment-refractory bipolar depression. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Wan Y Kwok,Victoria Stephens,Henry A Nasrallah
BACKGROUND Bipolar depression is a serious neuropsychiatric disorder associated with a high risk of morbidity and suicidality. Standard antidepressants approved for treating major depressive disorder fail to exert efficacy in bipolar depression. Although 5 agents have been developed for the treatment of bipolar depression, treatment resistance is still observed in some patients, and requires off-label
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Methamphetamine-associated catatonia: Case series and systematic review of the literature from 1943-2020. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Bojan Slavnic,Brian S Barnett,Seth McIntire,Robert Becker,Sindhu Saba,Krishna D Vellanki,Lindsay Honaker,Jeremy Weleff,Brendan T Carroll
BACKGROUND Catatonia due to a general medical condition may result from a variety of causes, including substance intoxication and withdrawal. Stimulants are occasionally associated with catatonia, though there has been little investigation of methamphetamine's relationship to catatonia. Here we present 5 cases of catatonia associated with methamphetamine use and a systematic review of the associated
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Better than we think: Is the treatment of depressed patients more effective than we think? Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Mark Zimmerman,Sin-Ying Lin
BACKGROUND Most studies of depression treatment rely on measures of symptom severity to evaluate outcome. We hypothesized that many patients would consider themselves to have benefitted significantly from treatment despite not being considered a responder according to a measure of depression symptom severity (ie, 50% reduction in symptom score). METHODS In our study, 854 patients with major depressive
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Concurrent Cotard and Koro syndromes in psychotic depression: Case report and literature review. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Matthew C Castellana,Preksha Arora-Hughes,Abigail S Green
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Stressors and coping mechanisms among pregnant women with psychiatric disorders during the COVID-19 pandemic. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-08-01 Rebecca S Hock,Anna Feeney,Heather A Harmon,Phoebe S Caplin,Lauren A Kobylski,Ella T Rossa,Adele C Viguera,Lee S Cohen,Marlene P Freeman
BACKGROUND Women with psychiatric disorders are vulnerable to relapse in pregnancy, and the COVID-19 pandemic has presented an additional stressor. METHODS Data came from a supplemental study offered to women enrolled in the Massachusetts General Hospital Center for Women's Mental Health National Pregnancy Registry for Psychiatric Medications. Registry participants were also invited to complete an
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A longitudinal follow-up study of Oklahoma City bombing survivors in the first quarter century after the disaster. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Carol S North,Katy McDonald,David E Pollio
BACKGROUND This study is one of the longest postdisaster prospective longitudinal studies of disaster-related psychopathology, completed nearly a quarter century after a terrorist bombing, and the longest follow-up study ever conducted using full diagnostic assessment in highly exposed disaster survivors. METHODS Oklahoma City bombing survivors (87% injured) were randomly selected from a state survivor
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COVID-19 and catatonia: Prevalence, challenges, pathophysiology, and treatment. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Joan Oh,Puneet Chawla Sahota,Tarannum Mohammadi,Basant K Pradhan,Maju Mathew Koola
BACKGROUND Emerging literature supports the association between acute COVID-19 infection and neuropsychiatric complications. This article reviews the evidence for catatonia as a potential neuropsychiatric sequela of COVID-19 infection. METHODS PubMed was searched using the terms catatonia, severe acute respiratory syndrome coronavirus 2, and COVID-19. Articles were limited to those published in the
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Temperament in trichotillomania and skin picking disorder. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Jon E Grant,Stephanie Valle,Ibrahim Aslan,Eve K Chesivoir,Samuel R Chamberlain
BACKGROUND Trichotillomania (TTM) and skin picking disorder (SPD) result in significant psychosocial burden. Despite this burden, however, risk factors related to the development of these disorders remain unclear. The present study assessed temperament in a well-characterized sample of adults with TTM or SPD. METHODS A total of 202 adults age 18 to 65 were enrolled; 44 had TTM, 30 had SPD, and 128
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Learning and achievement characteristics of sheltered homeless population subgroups. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Carol S North,Melissa Black,Sheila Gokul,David E Pollio,Faith M Scofield,Paul J Handal,Barry A Hong
BACKGROUND There is little systematic information about intelligence and academic achievement among sheltered homeless adults. This study adds descriptive data on intelligence and academic achievement, examines discrepancies across these concepts, and explores the associations among demographic and psychosocial characteristics in the context of intelligence categories and discrepancies. METHODS We
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Electroconvulsive therapy plus lithium is associated with less cognitive impairment and drug-induced delirium in bipolar depression compared to unipolar depression. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Nagy A Youssef,Neha Madangarli,Anil Bachu,Rikinkumar S Patel
BACKGROUND Although major depressive disorder (MDD) and bipolar depression can present with similar symptoms, biological differences exist. One difference is the possible variance in adverse effects associated with treatment. This study examined the association of cognitive impairment and delirium in patients treated with electroconvulsive therapy (ECT) plus lithium for MDD or bipolar depression. METHODS
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An accelerated course of TMS using intermittent theta burst for veterans with major depressive disorder: A case series. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Zachary D Zuschlag,Laura Bajor,Kimberly Van Trees,Sean Philips,Greg Sullivan,Christine Burke,F Andrew Kozel
BACKGROUND Transcranial magnetic stimulation (TMS) is a neuro-modulation technique for treatment-resistant major depressive disorder (MDD). Standard TMS protocols for MDD involve once-daily treatment for 6 to 9 weeks. We report a case series of an accelerated TMS protocol for outpatient MDD treatment. METHODS From July 2020 through January 2021, patients deemed appropriate candidates for TMS treatment
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Electroconvulsive therapy complicated by ventricular fibrillation: A case report. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-05-01 Brandon Neisewander,Nicholas Trapp
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Does gambling differ in people with a minority sexual orientation? Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Jon E Grant,Samuel R Chamberlain
BACKGROUND Gambling is common and there is growing concern about its public health implications. Little is known about how gambling differs in people with minority sexual identities. We sought to understand whether lesbian, gay, and bisexual (LGB) individuals differ from non-LGB individuals in terms of gambling and associated characteristics. METHODS A total of 534 participants age 18 to 29 who gambled
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Possible long-term impact of the loss of abortion services: Consequences for mental health of unwanted children. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Richard Balon
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Case report of lurasidone in the treatment of chronic tic disorders. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Calogero Crapanzano,Chiara Amendola,Jeremy Steen,Ilaria Casolaro
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A systematic review of alcohol consumption and disorders in relation to disasters. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Ala Ustyol,Sameer Sajjad,Fatemeh Safian,Josh M Raitt,Katherine Mills,Carol S North
BACKGROUND Excessive alcohol use and alcohol use disorders (AUDs) are serious medical problems in general populations. Alcohol use is associated with stressful events. Thus it is possible that problems with alcohol use increase in association with disasters. It is important to know the extent to which disasters contribute to these problems in exposed populations. METHODS This review focused on the
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Idiopathic burning mouth syndrome treated with electroconvulsive therapy. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Brandon Neisewander
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Repetitive transcranial magnetic stimulation (rTMS) is associated with increased abstinence in substance use disorders and comorbid depression. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Wael Foad,Karim Abdel Aziz,Maged Agour,Abdelazim Ali,Faris Alhammadi,Rami Alhawi,Samer Altamimi,Zahid Hussain,Amr Abdel Aty,Tarik Qassem
BACKGROUND Substance use disorders (SUDs) are associated with high rates of comorbid depression. Finding effective treatments for many of the substances of abuse is still an area of developing research. Repetitive transcranial magnetic stimulation (rTMS) is an established treatment for depression, but its effects in SUDs are less conclusive. Therefore, we aimed to investigate the effect of rTMS in
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Depressed patients who do not believe they deserve to get better: Prevalence, clinical characteristics, and treatment outcomes. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Mark Zimmerman,Lena Becker
BACKGROUND The aim of the present report from the Rhode Island Methods to Improve Diagnostic Assessment and Services (MIDAS) project was to examine the demographic and clinical features that distinguished depressed patients who did and did not indicate they deserved to feel better. METHODS A total of 490 depressed patients completed a clinical history questionnaire that included a question about whether
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The American Psychiatric Association Publishing Textbook of Anxiety, Trauma, and OCD-Related Disorders. Third Edition. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 James Allen Wilcox
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Clozapine withdrawal-induced catatonia treated with clozapine: A case report. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 James Alexander Scott,Ahmad Shobassy
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Hoarding Disorder. A Comprehensive Clinical Guide. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Richard Balon
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A link between seizure and stuttering disorders? A case report. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2023-02-01 Ariana Z Turk,Mutahir Farhan,Lama Al-Khoury,Gerald A Maguire,Shahriar SheikhBahaei
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Black-box warnings: Their consequences and how we should approach them. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Richard Balon
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Ketamine as potential treatment for postpartum depression: A narrative review. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 David Chen-Li,Leanna M W Lui,Joshua D Rosenblat,Orly Lipsitz,Kayla M Teopiz,Roger Ho,Maj Vinberg,Marina Golts,Muhammad Youshay Jawad,Yena Lee,Flora Nasri,Hartej Gill,Roger S McIntyre
BACKGROUND Postpartum depression (PPD) is a severe, debilitating mood disorder with consequences for both mothers and children, highlighting the need for rapid-acting and effective treatments for PPD. The aim of this narrative review is to synthesize the available literature on the administration of ketamine for PPD and propose ketamine as a viable and advantageous treatment. METHODS A search was conducted
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Frequency of illness anxiety (hypochondriasis) by proxy encountered by doctors in parents towards their children. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Dina Aly El-Gabry,Karim Abdel Aziz,Maitha Hasan Al-Hosani,Maryam Khaled Aljneibi,Amany Shouma,Dina Abu Zeid,Emmanuel Stip,Hussien Elkholy
BACKGROUND Illness anxiety disorder is a condition of having a persistent fear of having a serious or life-threatening illness despite few or no symptoms. Current classification systems assume that illness anxiety is experienced relative to one's own health, and not towards others ("by proxy"), yet it has been observed to occur in parents towards their children. This study was designed to survey doctors
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Anxiety and depression in stroke: An evaluation of these psychopathologies on outcomes of stroke type using the National Inpatient Sample. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Obiora Onwuameze,Vineka Heeramun,Steven Scaife,Andrew T Olagunju,Malathi Pilla,Jude Ogugua,Daniel Boeder
BACKGROUND Anxiety and depression have been reported to complicate the course of stroke. This study evaluated the association of anxiety and depression independently on ischemic vs non-ischemic stroke. METHODS A cross-sectional survey of 4,983,807 admissions for acute stroke from 1994 to 2013 in the National Inpatient Sample compared stroke patients with depression and anxiety to stroke patients with
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Emotion regulation difficulties link trait resilience and symptoms of depression and anxiety in psychiatric outpatients. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Joseph M Diehl,Moria J Smoski,Mark Zimmerman
BACKGROUND Despite negative associations of trait resilience with depression and anxiety symptoms, the mechanisms by which resilience may buffer against these symptoms remain underexplored. This study investigated emotion regulation difficulties as a potential link in the relationship between trait resilience and depression and anxiety severity in psychiatric outpatients (N = 353). METHODS Participants
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Naltrexone for sexual sadism disorder in an adolescent. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Amber Lemons,Christopher Piatz,Adrian Schenk,Rebecca M Reiss
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Delusional parasitosis successfully controlled with lurasidone: A case report. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Ashish Meshram,Serge Sevy
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Concomitant mood disorder and stutter in a post-COVID-19 patient. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Zeyd Sarwar,Estee George,Manzoor Elahi
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A randomized, double-blind, clinical pilot trial of adjunct ketone supplement compared to placebo for treating posttraumatic stress disorder. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Nagy A Youssef,Angelia Maleah Holland-Winkler,Phung Phung,Jennifer L Waller,Sonali Ponkshe
BACKGROUND Despite some evidence of the helpful role of ketones in some neuropsychiatric disorders, there are no clinical trials that examine these agents for posttraumatic stress disorder (PTSD). Our aim was to investigate whether ketone salt supplementation can improve PTSD symptoms in a randomized, placebo-controlled trial. METHODS A total of 21 participants were recruited and randomized to placebo
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Impaired insight into illness is unrelated to subjective happiness, success, and life satisfaction in schizophrenia. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Julia Kim,Laura Romero,Yusuke Iwata,Fernando Caravaggio,Gary Remington,Ariel Graff-Guerrero,Philip Gerretsen,Ofer Agid
BACKGROUND Impaired insight into illness is a common feature of schizophrenia. Improved insight is associated with better treatment adherence and clinical outcomes. At the same time, improving insight has been suggested to increase depressive symptoms and diminish quality of life. The aim of this study was to examine the associations between impaired insight and degree of subjective happiness, perceived
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Telemedicine for outpatient treatment of depressive disorders. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Georg Juckel,Eva Neumann,Arnd Jäger,Magnus Welz,Jessica Heinrich,Katharina Pehnke,Ida S Haussleiter,Barbara Emons
BACKGROUND The newly developed app TellUs is a digital offering for psychiatric outpatient treatment that includes diagnostic and therapeutic tools. The aim of this study was to test the clinical efficiency and patient satisfaction of TellUs. METHODS Sixty-four patients with depressive disorder took part in the study for 3 months. The intervention group was treated digitally with TellUs and the control
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Recurrent antimicrobial exposure and acute psychosis. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-11-01 Evan Ketcham,Brian J Miller
BACKGROUND There is an increased prevalence of recent antimicrobial exposure in patients with acute psychosis. We previously found recurrent urinary tract infections (UTIs) in some patients with psychosis. We evaluated the prevalence of recurrent antimicrobial exposure in acutely ill inpatients with psychosis. METHODS We performed a retrospective chart review of 85 patients age 18 to 65 with multiple
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The need to clarify professional terminology in psychiatry. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Carol S North,Betty Pfefferbaum
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COVID-19 leading to new-onset psychosis and suicide. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Erin Semple,Amy Beauchamp,Ahmad Shobassy
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Creutzfeldt-Jakob disease presenting as catatonia with desaturation on lorazepam challenge. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Himangshu Rathinakumar,Clayton Schutz,Ross Smith,Brandi R French,Eman Mhadi,Kimberly Brandt
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Neurobehavioral follow-up of children exposed to selective serotonin reuptake inhibitors in utero. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Lee S Cohen,Sinéad M Rhodes,Lauren D Claypoole,Lina Góez-Mogollón,Alexandra Z Sosinsky,Danna Moustafa,Olivia B Noe,Sara A McElheny,Laura J Cheng,Johanna R Bick,Marlene P Freeman,Charles A Nelson
BACKGROUND Systematic data regarding long-term neurobehavioral effects of maternal antidepressant use during pregnancy are sparse. The aim of this study was to evaluate the impact of gestational exposure to antidepressants on later neurodevelopmental function. METHODS This study describes a cohort of mother-child dyads (44 mothers, 54 children) in which maternal depressive symptoms and medication exposures
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Dissociation and psychopathology in Kenyan survivors of a terrorist bombing. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Ala Ustyol,Josh M Raitt,C Robert Cloninger,Carol S North
BACKGROUND Dissociation is a serious psychological condition that is characterized as a pathological outcome of trauma-related experience. Thus, dissociation could be expected to develop in survivors of disaster trauma and to be associated with trauma exposure and psychopathology. METHODS A sample of 278 disaster-affected Kenyans was assessed 8 to 10 months after the 1998 terrorist bombing of the US
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A prospective longitudinal study of tobacco use and tobacco use disorder in a homeless population. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Esha Hansoti,David E Pollio,Carol S North
BACKGROUND Little is known about smoking habits and disorders among homeless populations. Previous research has not generally differentiated tobacco use from tobacco use disorders in this population. Known associations of tobacco use and morbidity and mortality in general populations may also apply to homeless populations. METHODS A 2-year longitudinal prospective study of 255 homeless individuals
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A systematic mental health assessment of first-year students at a historically Black college. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Jessica R Moore,David E Pollio,Carol Tamminga,Preston Wiles,Carol S North
BACKGROUND A systematic diagnostic mental health assessment was conducted with first-year students at Paul Quinn College, a small historically Black college/university (HBCU) in Dallas, Texas. METHODS A sample of 128 students was assessed with the Mini-International Neuropsychiatric Interview for DSM-5 and the Childhood Trauma Questionnaire. RESULTS Nearly one-third of students were diagnosed with
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Krankheitsreste: The residual signs of catatonia. A case series. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-08-01 Brendan T Carroll,Stephen L Scott,Heather P M Theibert,Bojan Slavnic,Krishna D Vellanki
BACKGROUND Catatonic signs were first described by 19th- and 20th-century researchers. An important concept known as "Krankheitsreste," or the residual signs of catatonia, was described by Kraepelin in 1896. Modern researchers describe patients who demonstrate "partial response to the treatment of catatonia with residual signs." Kraepelin observed that these signs occurred between catatonic episodes
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Anxiety, depression, and rejection towards parents among individuals who grew up in a hoarded home. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-02-01 Andrew G Guzick,Suzanne Chabaud,Cecilia Garrett,Eric A Storch
BACKGROUND Limited research has investigated parent-child conflict and mental health among adult children of parents with hoarding problems. METHODS Four hundred fourteen participants who reported clinically significant parental hoarding completed assessments of parental hoarding characteristics (clutter, insight, difficulty discarding), feelings of rejection towards their parent, depression, and generalized
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Ketamine for treatment of mood disorders and suicidality: A narrative review of recent progress. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2022-02-01 Michael D Kritzer,Nicholas A Mischel,Jonathan R Young,Christopher S Lai,Prakash S Masand,Steven T Szabo,Sanjay J Mathew
BACKGROUND Mood disorders are a leading cause of morbidity. Many patients experience treatment-resistant depression (TRD), and suicide rates are rising. Faster-acting and more effective antidepressant medications are needed. Four decades of research has transformed the use of ketamine from an anesthetic to an outpatient treatment for major depressive disorder (MDD). Ketamine is a N-methyl-d-aspartate
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Doll therapy in dementia: Facts and controversies Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2021-02-01 Kala Chinnaswamy, Dominic M. DeMarco, George T. Grossberg
BACKGROUND The management of major neurocognitive disorder (MNCD), formerly known as dementia, is of increasing concern as the elderly population continues to grow. Doll therapy (DT) is a controversial method observed in clinical practice that has both promising benefits and potential ethical concerns. To date, little research has been done on this therapy. METHODS A PubMed search was performed using
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Increased mortality in patients with standard EEG findings of 'diffuse slowing'. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2021-02-01 Robert Wanzek,Nicholas Bormann,Yaseen Shabbir,Taku Saito,Thoru Yamada,Gen Shinozaki
BACKGROUND We aimed to confirm the association between slow brain wave activity typically described as "diffuse slowing" on standard electroencephalogram (EEG) and patient outcomes, including mortality. METHODS This retrospective study was conducted with patient chart data from March 2015 to March 2017 at a tertiary care academic hospital in the midwestern United States. In total, 1,069 participants
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Less is more: Deprescribing anticholinergic medications in persons with severe mental illness. Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2021-02-01 Ana M Lupu,Kathryn L MacCamy,Jessica M Gannon,Jaspreet S Brar,K N Roy Chengappa
BACKGROUND Long-term prescribing of anticholinergic medications (ACM) for antipsychotic-associated extrapyramidal symptoms (EPS) is not recommended, yet is widely prevalent. Adverse effects of ACM include memory impairment, dry mouth, constipation, blurred vision, urinary retention, and tachycardia, which can seriously impact quality of life. This quality improvement deprescription project sought to
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Acutely ill psychiatric inpatients and antimicrobial exposure Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2020-11-01 Kaitlin P. Kehoe, Brian J. Miller
BACKGROUND Patients with schizophrenia, bipolar disorder, and major depressive disorder (MDD) have increased infections. We explored the association between recent antimicrobial exposure and acute psychiatric illness. METHODS We performed a retrospective chart review of 267 acutely ill patients age 18 to 65. There were 92 patients with schizophrenia, 42 with bipolar disorder, 61 with MDD, and 72 with
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Double-blind, placebo-controlled, proof-of-concept trial of a kappa-selective opioid receptor antagonist augmentation in treatment-resistant depression Annals of Clinical Psychiatry (IF 1.5) Pub Date : 2020-11-01 Maurizio Fava, Erica Mazzone, Marlene Freeman, Martina Flynn, Heidi Judge, Bettina Hoeppner, Rebecca S. Hock, Amy Shui, Matthew Macaluso, Mary F. Morrison, Linda L. Carpenter, Richard Shelton, John Zajecka, George I. Papakostas
BACKGROUND Kappa-opioid antagonism may possess antidepressant properties. We assessed, in a proof-of-concept pilot trial among patients with major depressive disorder with inadequate response to antidepressants, the efficacy of adjunctive CERC-501 (formerly LY2456302), a kappaselective opioid receptor antagonist. METHODS In a Sequential Parallel Comparison Design study, patients were pre-randomized