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Combined metabolomic and microbial community analyses reveal that biochar and organic manure alter soil C-N metabolism and greenhouse gas emissions Environ. Int. (IF 10.3) Pub Date : 2024-09-21 Wendan Xiao, Qi Zhang, Shouping Zhao, De Chen, Zhen Zhao, Na Gao, Miaojie Huang, Xuezhu Ye
The use of biochar to reduce the gas emissions from paddy soils is a promising approach. However, the manner in which biochar and soil microbial communities interact to affect CO2, CH4, and N2O emissions is not clearly understood, particularly when compared with other amendments. In this study, high-throughput sequencing, soil metabolomics, and quantitative real-time PCR were utilized to compare the
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Dermal exposure assessment of formal e-waste dismantlers to flame retardants and plasticizers using passive sampling methodologies Environ. Int. (IF 10.3) Pub Date : 2024-09-19 A. Balasch, A. Peris, C. Reche, T. Moreno, E. Eljarrat
The recycling of e-waste can lead to the release of organic chemicals when materials containing additives are subjected to dismantling and grinding. In this context, the exposure of workers from a Catalonian e-waste facility to flame retardants and plasticizers (including organophosphate esters (OPEs), polybrominated diphenyl ethers (PBDEs), novel brominated flame retardants (NBFRs) and dechloranes)
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Integrated assessment of simultaneous threshold exceedance of heat, air pollution and airborne allergenic pollen across Europe Environ. Int. (IF 10.3) Pub Date : 2024-09-19 Bernice Scholten, Koen van der Sanden, Blaise Kelly, Bas Henzing, Anjoeka Pronk, W. Marty Blom, Lisa Klous, Boris R.M. Kingma
Climate change is expected to elevate exposure to several environmental health risk factors, including extreme environmental temperatures, air pollution and airborne allergenic pollen. Given their interconnected effects on respiratory and cardiovascular diseases, it is crucial to evaluate these exposures simultaneously. Yet, comprehensive efforts to do so remain limited. This research aims to develop
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Ambient fine particulate matter and its constituents may exacerbate the acceleration of aging in adults Environ. Int. (IF 10.3) Pub Date : 2024-09-18 Cui Guo, Jun Yang, Jun Ma, Jie Chen, Siyi Chen, Yiling Zheng, Bo Huang, Jianzhen Yu, Tiantian Li, Shenjing He
Both ambient fine particulate matter (PM2.5) and aging are important urban concerns. However, the associations between PM2.5 constituents and the acceleration of aging (AA) remain unclear. We included 16,051 adults (aged 25–80 years) with 19,252 medical observations in Taiwan during 2008−2017. 2-year average PM2.5 and its five major constituents were assessed using a two-stage machine learning model
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Cold exposure accelerates lysine catabolism to promote cold acclimation via remodeling hepatic histone crotonylation Environ. Int. (IF 10.3) Pub Date : 2024-09-16 Chong Xue, Sijin Zhu, Yang Li, Xiaoming Chen, Liang Lu, Peng Su, Qian Zhang, Xinqin Liu, Ruili Guan, Zongcai Liu, Zhiwei Zhao, Shan Tang, Jingyuan Chen, Jianbin Zhang, Wenbin Zhang, Huanyu Lu, Wenjing Luo
Cold environments pose serious threats on human health, with increased risk for myocardial infarction, stroke, frostbite, and hypothermia. Acquired cold acclimation is required to minimize cold-induced injures and to improve metabolic health. However, the underlying mechanisms remain to be fully elucidated.
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Association between long-term exposure to low ambient PM2.5 and cardiovascular hospital admissions: A UK Biobank study Environ. Int. (IF 10.3) Pub Date : 2024-09-14 Jacopo Vanoli, Jennifer K. Quint, Sanjay Rajagopalan, Massimo Stafoggia, Sadeer Al-Kindi, Malcolm N. Mistry, Pierre Masselot, Arturo de la Cruz Libardi, Chris Fook Sheng Ng, Lina Madaniyazi, Antonio Gasparrini
A causal link between air pollution exposure and cardiovascular events has been suggested. However fewer studies have investigated the shape of the associations at low levels of air pollution and identified the most important temporal window of exposure. Here we assessed long-term associations between particulate matter < 2.5 µm (PM2.5) at low concentrations and multiple cardiovascular endpoints using
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Association between temperature and occupational injuries in Spain: The role of contextual factors in workers’ adaptation Environ. Int. (IF 10.3) Pub Date : 2024-09-12 Constanza Vielma, Hicham Achebak, Marcos Quijal-Zamorano, Simon J Lloyd, Guillaume Chevance, Joan Ballester
Extensive evidence links both cold and hot temperatures to an increased incidence of occupational injuries. Contextual modifiers of the temperature-injury association have been scarcely researched. The present study addresses temporal and spatial variations to identify factors associated with (mal)adaptation to heat and cold among Spanish workers.
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Overcoming China’s animal waste disposal challenge brought by elevated levels of veterinary antimicrobial residues and antimicrobial resistance Environ. Int. (IF 10.3) Pub Date : 2024-09-12 Grace M. Cheng, Hefa Cheng
Direct application of animal waste on farmlands was banned in China recently, rendering organic fertilizer production a sound solution for disposing of animal manures and recycling their materials and nutrients. Due to the overuse of antimicrobials in livestock and poultry farms, manure-based organic fertilizers often contain elevated residues of antimicrobials and abundant antimicrobial resistance
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Short-term effects of wildfire-specific fine particulate matter and its carbonaceous components on perinatal outcomes: A multicentre cohort study in New South Wales, Australia Environ. Int. (IF 10.3) Pub Date : 2024-09-12 Sylvester Dodzi Nyadanu, Damien Foo, Gavin Pereira, Loretta J. Mickley, Xu Feng, Michelle L. Bell
Epidemiological evidence on the association between wildfire-specific fine particulate matter (PM2.5) and its carbonaceous components with perinatal outcomes is limited.
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Effect of per- and polyfluoroalkyl substances on neurodevelopment: Evidence-based risk assessment in the TRAEC strategy context Environ. Int. (IF 10.3) Pub Date : 2024-09-12 Jie Ning, Chaoshun Ding, Haoyi Xu, Zhaofeng Liu, Quanquan Guan, Yankai Xia, Qing Xu
Although emerging evidence on the association between per- and polyfluoroalkyl substances (PFASs) and neurodevelopment have been investigated, there is no consensus on the effect of maternal PFASs on neurodevelopment in offspring. Here, we assessed the risk of maternal PFASs exposure on the neurodevelopment of offspring using a novel Targeted Risk Assessment of Environmental Chemicals (TRAEC) strategy
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Widespread occurrence of glyphosate and aminomethylphosphonic acid in indoor dust from urban homes across the United States and its contribution to human exposure Environ. Int. (IF 10.3) Pub Date : 2024-09-11 Zhong-Min Li, HuiHo Jeong, Kurunthachalam Kannan
Glyphosate is the most widely used herbicide worldwide, with concerns over human exposure and potential health risks. Nevertheless, little is known about the sources of human exposure to glyphosate and its degradation product, aminomethylphosphonic acid (AMPA). In this study, we measured glyphosate and AMPA in 99 indoor dust samples collected from urban homes in sixteen states in the USA. Glyphosate
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Domain knowledge-enhanced multi-spatial multi-temporal [formula omitted] forecasting with integrated monitoring and reanalysis data Environ. Int. (IF 10.3) Pub Date : 2024-09-11 Yuxiao Hu, Qian Li, Xiaodan Shi, Jinyue Yan, Yuntian Chen
Accurate air quality forecasting is crucial for public health, environmental monitoring and protection, and urban planning. However, existing methods fail to effectively utilize multi-scale information, both spatially and temporally. There is a lack of integration between individual monitoring stations and city-wide scales. Temporally, the periodic nature of air quality variations is often overlooked
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Transforming contaminant ligands at water–solid interfaces via trivalent metal coordination Environ. Int. (IF 10.3) Pub Date : 2024-09-11 Qiandi Wang, Qiongying Xu, Wenzong Liu, Meng Jiao, Zhuqi Chen, Aijie Wang
In environmental matrices, the migration and distribution of contaminants at water–solid interfaces play a crucial role in their capture or dissemination. Scientists working in environmental remediation and wastewater treatment are increasingly aware of metal–contaminant coordination; however, interfacial behaviors remain underexplored. Here, we show that trivalent metal ions (e.g. Al3+ and Fe3+) mediate
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Unraveling the fate of 6PPD-Q in aquatic environment: Insights into formation, dissipation, and transformation under natural conditions Environ. Int. (IF 10.3) Pub Date : 2024-09-11 Xiaopeng Yan, Jin Xiao, Claude Kiki, Yuanyuan Zhang, Habasi Patrick Manzi, Guangpu Zhao, ShengDa Wang, Qian Sun
The widespread occurrence of N-(1,3-Dimethylbutyl)-N′-phenyl-p-phenylenediamine-quinone (6PPD-Q) in aquatic environments and its hazards to aquatic species underscore the necessity of comprehending its environmental fate. Here, we investigated the transformation from 6PPD to 6PPD-Q and the attenuation of 6PPD-Q in surface water under natural conditions. Contrary to prior findings, this work revealed
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A conceptual framework for landscape-based environmental risk assessment (ERA) of pesticides Environ. Int. (IF 10.3) Pub Date : 2024-09-10 Jose V. Tarazona, Mercedes de Alba-Gonzalez, Carole Bedos, Pierre Benoit, Colette Bertrand, Olivier Crouzet, Cécile Dagès, Jean-Lou CM Dorne, Ana Fernandez-Agudo, Andreas Focks, Maria del Carmen Gonzalez-Caballero, Alexandra Kroll, Matthias Liess, Susana Loureiro, Manuel E. Ortiz-Santaliestra, Jes J. Rasmussen, Raphaël Royauté, Maj Rundlöf, Ralf B. Schäfer, Stephen Short, Ayesha Siddique, José Paulo
While pesticide use is subject to strict regulatory oversight worldwide, it remains a main concern for environmental protection, including biodiversity conservation. This is partly due to the current regulatory approach that relies on separate assessments for each single pesticide, crop use, and non-target organism group at local scales. Such assessments tend to overlook the combined effects of overall
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Circ_0025373 inhibits carbon black nanoparticles-induced malignant transformation of human bronchial epithelial cells by affecting DNA damage through binding to MSH2 Environ. Int. (IF 10.3) Pub Date : 2024-09-07 Han Zhang, Wenfeng Lu, Lan Qiu, Saifeng Li, Liqiu Qiu, Mengnan He, Xintong Chen, Jiajing Wang, Jingwen Fang, Chenghui Zhong, Meiqi Lan, Xiaole Xu, Yun Zhou
Carbon black nanoparticles (CBNPs) have been demonstrated to induce DNA damage in epithelial cells. However, the potential of the damage to initiate carcinogenesis and the underlying mechanism remain poorly understood. Therefore, we constructed an in vitro model of malignant transformation of human bronchial epithelial cells (16HBE-T) by treating 40 μg/mL CBNPs for 120 passages. We observed tumor-like
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Epigenetic alterations in bioaccumulators of cadmium: Lessons from mammalian kidneys and plants Environ. Int. (IF 10.3) Pub Date : 2024-09-07 Stephanie Frings, Romy Schmidt-Schippers, Wing-Kee Lee
Faced with unpredictable changes in global weather patterns, release and redistribution of metals through land erosion and water movements add to the increasing use of metals in industrial activities causing high levels of environmental pollution and concern to the health of all living organisms. Cadmium is released into the environment by smelting and mining, entering the food chain via contaminated
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Impacts of different vehicle emissions on ozone levels in Beijing: Insights into source contributions and formation processes Environ. Int. (IF 10.3) Pub Date : 2024-09-07 Jingyuan Cao, Jun Liu, Ying Cheng, Siqi Ai, Fangzhou Li, Tao Xue, Qiang Zhang, Tong Zhu
Beijing, with the highest number of motor vehicles in China, significantly contributes to O3 pollution through substantial NOx and VOC emissions in the on-road transportation sector. Understanding the unique impact of emissions from different vehicle types on O3 levels is crucial for developing targeted strategies for O3 pollution. This study applied the Community Multiscale Air Quality Modeling System
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Combining Google traffic map with deep learning model to predict street-level traffic-related air pollutants in a complex urban environment Environ. Int. (IF 10.3) Pub Date : 2024-09-06 Peng Wei, Song Hao, Yuan Shi, Abhishek Anand, Ya Wang, Mengyuan Chu, Zhi Ning
Traffic-related air pollution (TRAP) is a major contributor to urban pollution and varies sharply at the street level, posing a challenge for air quality modeling. Traditional land use regression models combined with data from fixed monitoring stations may be unable to predict and characterize fine-scale TRAP, especially in complex urban environments influenced by various features. This study aims
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Effect of anaerobic digestion on pathogens and antimicrobial resistance in the sewage sludge Environ. Int. (IF 10.3) Pub Date : 2024-09-05 Elena Franchitti, Matilde Pedullà, Anne Mette Madsen, Deborah Traversi
Antimicrobial resistance (AMR) is recognized as a global threat. AMR bacteria accumulate in sewage sludge however, knowledge on the persistence of human pathogens and AMR in the sludge line of the wastewater treatment is limited. Sludge can be used, with or without additional treatment, as fertilizer in agricultural fields. The aim of this study is to obtain knowledge about presence of human pathogens
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Long-term contributions of VOC sources and their link to ozone pollution in Bronx, New York City Environ. Int. (IF 10.3) Pub Date : 2024-09-03 Lucille Borlaza-Lacoste, Md. Aynul Bari, Cheng-Hsuan Lu, Philip K. Hopke
Changes in energy and environmental policies along with changes in the energy markets of New York State over the past two decades, have spurred interest in evaluating their impacts on emissions from various energy generation sectors. This study focused on quantifying these effects on VOC (volatile organic compounds) emissions and their subsequent impacts on air quality within the New York City (NYC)
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Exposure levels and maternal transfer of emerging organophosphate flame retardants (OPFRs) in pregnant women: Comparison with traditional OPFRs Environ. Int. (IF 10.3) Pub Date : 2024-09-02 Linwan Li, Fumei Gao, Chong Huang, Jianying Hu
Prenatal exposure to organophosphorus flame retardants (OPFRs) has been linked with adverse effects on reproductive health, and new OPFRs are continually emerging. In this study, emerging OPFRs, such as bis(2-ethylhexyl) phenyl phosphate (BEHPP), triamyl phosphate (TAP), tris(4-tert-butylphenyl) phosphate (T4tBPPP), oxydi-2,1-ethanediyl phosphoric acid tetrakis(2 chloro-1-methylethyl) ester (RDT905)
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Knowledge-based machine learning for predicting and understanding the androgen receptor (AR)-mediated reproductive toxicity in zebrafish Environ. Int. (IF 10.3) Pub Date : 2024-09-02 Lei Xin, Sisi Liu, Wenjun Shi, Guang-Guo Ying, Xinyue Hui, Chang-Er Chen
Traditional methods for identifying endocrine-disrupting chemicals (EDCs) that activate androgen receptors (AR) are costly, time-consuming, and low-throughput. This study developed a knowledge-based deep neural network model (AR-DNN) to predict AR-mediated adverse outcomes on female zebrafish fertility. This model started with chemical fingerprints as the input layer and was implemented through a five-layer
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A harmonized occupational biomonitoring approach Environ. Int. (IF 10.3) Pub Date : 2024-08-31 Nancy B. Hopf, Christophe Rousselle, Devika Poddalgoda, Farida Lamkarkach, Jos Bessems, Kaspar Schmid, Kate Jones, Koki Takaki, Ludwine Casteleyn, Maryam Zare Jeddi, Michael Bader, Michael Koller, Patience Browne, Rex FitzGerald, Susana Viegas, Thomas Göen, Tiina Santonen, Virpi Väänänen, Radu - Corneliu Duca, Robert Pasanen-Kase
Biomonitoring has been widely used in assessing exposures in both occupational and public health complementing chemical risk assessments because it measures the concentrations of chemical substances in human body fluids (e.g., urine and blood). Biomonitoring considers all routes and sources of exposure. An occupational biomonitoring guidance document has been elaborated (OECD Occupational Biomonitoring
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Personalized mixture toxicity testing: A proof-of-principle in vitro study evaluating the steroidogenic effects of reconstructed contaminant mixtures measured in blood of individual adults Environ. Int. (IF 10.3) Pub Date : 2024-08-30 Denise Strand, Bo Lundgren, Ingvar A Bergdahl, Jonathan W Martin, Oskar Karlsson
Chemical risk assessments typically focus on single substances, often overlooking real-world co-exposures to chemical mixtures. Mixture toxicology studies using representative mixtures can reveal potential chemical interactions, but these do not account for the unique chemical profiles that occur in the blood of diverse individuals. Here we used the H295R steroidogenesis assay to screen personalized
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The effect of exposure to radiofrequency fields on cancer risk in the general and working population: A systematic review of human observational studies – Part I: Most researched outcomes Environ. Int. (IF 10.3) Pub Date : 2024-08-30 Ken Karipidis, Dan Baaken, Tom Loney, Maria Blettner, Chris Brzozek, Mark Elwood, Clement Narh, Nicola Orsini, Martin Röösli, Marilia Silva Paulo, Susanna Lagorio
The objective of this review was to assess the quality and strength of the evidence provided by human observational studies for a causal association between exposure to radiofrequency electromagnetic fields (RF-EMF) and risk of the most investigated neoplastic diseases.
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A randomized controlled trial of a housing intervention to reduce endocrine disrupting chemical exposures in children Environ. Int. (IF 10.3) Pub Date : 2024-08-30 Alan J. Fossa, Katherine E. Manz, George D. Papandonatos, Aimin Chen, Mark J. La Guardia, Bruce P. Lanphear, Robert C.Hale, Alexandra Pagano, Kurt D. Pennell, Kimberly Yolton, Joseph M. Braun
Few studies have considered household interventions for reducing endocrine disrupting chemical (EDC) exposures. We conducted a secondary analysis of a randomized controlled trial, originally designed to reduce lead exposure, to evaluate if the intervention lowered EDC exposures in young children. Study participants were children from the Cincinnati, Ohio area (n = 250, HOME Study). Prenatally, families
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Identifying groups at-risk to extreme heat: Intersections of age, race/ethnicity, and socioeconomic status Environ. Int. (IF 10.3) Pub Date : 2024-08-30 Austin Clark, Sara Grineski, David S. Curtis, Ethan Siu Leung Cheung
Anthropogenic climate change has resulted in a significant rise in extreme heat events, exerting considerable but unequal impacts on morbidity and mortality. Numerous studies have identified inequities in heat exposure across different groups, but social identities have often been viewed in isolation from each other. Children (5 and under) and older adults (65 and older) also face elevated risks of
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Integrated multi-omics approaches reveal the neurotoxicity of triclocarban in mouse brain Environ. Int. (IF 10.3) Pub Date : 2024-08-30 Qian Song, Chengchen Hu, Xueying Zhang, Pengweilin Ji, Yansong Li, Hanyong Peng, Yuxin Zheng, Hongna Zhang
Triclocarban (TCC) is an antimicrobial ingredient that commonly incorporated in many household and personal care products, raising public concerns about its potential health risks. Previous research has showed that TCC could cross the blood–brain barrier, but to date our understanding of its potential neurotoxicity at human-relevant concentrations remains lacking. In this study, we observed anxiety-like
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Recent advances in environmental antibiotic resistance genes detection and research focus: From genes to ecosystems Environ. Int. (IF 10.3) Pub Date : 2024-08-29 Bowei Ouyang, Cong Yang, Ziyue Lv, Baowei Chen, Lei Tong, Jianbo Shi
Antibiotic resistance genes (ARGs) persistence and potential harm have become more widely recognized in the environment due to its fast-paced research. However, the bibliometric review on the detection, research hotspot, and development trend of environmental ARGs has not been widely conducted. It is essential to provide a comprehensive overview of the last 30 years of research on environmental ARGs
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Response to letter from Bevington M., Electrosensitivity UK Environ. Int. (IF 10.3) Pub Date : 2024-08-29 Xavier Bosch-Capblanch, Ekpereonne Esu, Chioma Moses Oringanje, Stefan Dongus, Hamed Jalilian, John Eyers, Christian Auer, Martin Meremikwu, Martin Röösli
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Thirdhand smoke exposure promotes gastric tumor development in mouse and human Environ. Int. (IF 10.3) Pub Date : 2024-08-26 Chengfei Jiang, Lingyan Chen, Chunping Ye, Suzaynn F. Schick, Peyton Jacob III, Yingjia Zhuang, Jamie L. Inman, Changbin Chen, Lara A. Gundel, Hang Chang, Antoine M. Snijders, Xiaoping Zou, Jian-Hua Mao, Bo Hang, Pin Wang
The pollution of indoor environments and the consequent health risks associated with thirdhand smoke (THS) are increasingly recognized in recent years. However, the carcinogenic potential of THS and its underlying mechanisms have yet to be thoroughly explored. In this study, we examined the effects of short-term THS exposure on the development of gastric cancer (GC) in vitro and in vivo. In a mouse
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Neighbourhood environments and cognitive health in the longitudinal Personality and Total Health (PATH) through life study: A 12-year follow-up of older Australians Environ. Int. (IF 10.3) Pub Date : 2024-08-25 Ester Cerin, Maria V. Soloveva, Miguel A. Molina, Ralf-Dieter Schroers, Luke D. Knibbs, Muhammad Akram, Yu-Tzu Wu, Suzanne Mavoa, Matthew Prina, Perminder S. Sachdev, Vibeke Sorensen Catts, Bin Jalaludin, Govinda Poudel, Mark Symmons, Anthony Barnett, Md Hamidul Huque, Yvonne Leung, Nicolas Cherbuin, Kaarin J. Anstey
Urban neighbourhood environments may impact older adults’ cognitive health. However, longitudinal studies examining key environmental correlates of cognitive health are lacking. We estimated cross-sectional and longitudinal associations of neighbourhood built and natural environments and ambient air pollution with multiple cognitive health outcomes in Australian urban dwellers aged 60+ years.
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Pesticide residues and polyphenols in urine – A combined LC-HRMS screening to reveal intake patterns Environ. Int. (IF 10.3) Pub Date : 2024-08-25 Carolin Huber, Werner Brack, Stefan Röder, Martin von Bergen, Ulrike Rolle-Kampczyk, Ana Claudia Zenclussen, Martin Krauss, Gunda Herberth
Human exposure to pesticides in the general population occurs mainly through food consumption. However, specific dietary habits or food products that contribute to pesticide exposure are often unknown. In this study, we propose a combined screening for polyphenols and pesticide residues by liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS) to assess the diet and the associated
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Identification of candidate exposure biomarkers for acetyl tributyl citrate and acetyl triethyl citrate using suspect screening in human liver microsomes Environ. Int. (IF 10.3) Pub Date : 2024-08-24 Hyojoo Choi, Eu-Kyung Jo, Jinhyun Kwon, Daeho Kang, Junho Jeon, Younglim Kho, Mi-Yeon Shin, Sungkyoon Kim
Acetyl tributyl citrate (ATBC) and acetyl triethyl citrate (ATEC) are increasingly used as alternatives to phthalates in various products, including food packaging, medical devices, and personal care items, raising concerns about their potential health impacts. This study aimed to investigate the in vitro human metabolism of ATBC and ATEC and identify potential exposure biomarkers applicable in human
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Carcinogenic industrial air pollution and postmenopausal breast cancer risk in the National Institutes of Health AARP Diet and Health Study Environ. Int. (IF 10.3) Pub Date : 2024-08-24 Jessica M. Madrigal, Caroline N. Pruitt, Jared A. Fisher, Linda M. Liao, Barry I. Graubard, Gretchen L. Gierach, Debra T. Silverman, Mary H. Ward, Rena R. Jones
Chemicals emitted from industrial facilities include known or suspected mammary carcinogens and endocrine disruptors, but epidemiologic studies are limited. We evaluated associations between air emissions of multiple carcinogenic chemicals and postmenopausal breast cancer risk in a large prospective U.S. cohort.
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Mapping air quality trends across 336 cities in India: Insights from three decades of monitoring (1987–2019) Environ. Int. (IF 10.3) Pub Date : 2024-08-24 Garima Sharma, Medhavi Gupta, Prashant Gargava, Sri Harsha Kota
Over a span of 34 years (1987–2019), an in-depth analysis of PM10, SO2, and NO2 trends across India was conducted using data from the National Ambient Air Quality Monitoring Programme’s manual monitoring stations in 336 cities. The study encompassed six geographical regions over three time blocks, revealing a correlation between the expansion of monitoring networks and the nation’s economic growth
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An innovative mixture sampling strategy with uniform design: Application to global sensitivity analysis of mixture toxicity Environ. Int. (IF 10.3) Pub Date : 2024-08-24 Ting-Ting Ding, Ze-Jun Wang, Meng-Ting Tao, Zhong-Wei Gu, Ru-Jun Chen, Ya-Qian Xu, Shu-Shen Liu
Global sensitivity analysis combined with quantitative high-throughput screening (GSA-qHTS) uses random starting points of the trajectories in mixture design, which may lead to potential contingency and a lack of representativeness. Moreover, a scenario in which all factor levels were at stimulatory effects was not considered, thereby hindering a comprehensive understanding of GSA-qHTS. Accordingly
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Pathogen shape: Implication on pathogenicity via respiratory deposition Environ. Int. (IF 10.3) Pub Date : 2024-08-23 Lipeng Lv, Yahong Chen, Bin Zhao
The shape of environmental aerosols contributes to the discrepancy in their dynamic behavior compared to spherical particles, which have received inadequate consideration. We reported deposition patterns of aerosols and aerosol-transmissible pathogens in real human respiratory systems, taking into account their actual shape, using a validated computational-based model. We found that the shape of the
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The trends of non-accidental mortality burden attributed to compound hot-dry events in China and its provinces in a global warming world Environ. Int. (IF 10.3) Pub Date : 2024-08-23 Guanhao He, Yi Lin, Jianxiong Hu, Yang Chen, Yanfang Guo, Min Yu, Fangfang Zeng, Hailai Duan, Ruilin Meng, Chunliang Zhou, Yize Xiao, Biao Huang, Weiwei Gong, Jiangmei Liu, Tao Liu, Maigeng Zhou, Wenjun Ma
Global warming has provoked more co-occurrence of hot extreme and dry extreme, namely compound hot-dry events (CHDEs). However, their health impacts have seldom been investigated. This study aimed to characterize CHDEs and assess its mortality burden in China from 1990 to 2100.
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Chemical and non-chemical stressors in a postpartum cohort through wristband and self report data: Links between increased chemical burden, economic, and racial stress Environ. Int. (IF 10.3) Pub Date : 2024-08-23 Elise Hickman, Jenna Frey, Amanda Wylie, Hadley J. Hartwell, Nicholas J. Herkert, Sarah J. Short, W. Roger Mills-Koonce, Rebecca C. Fry, Heather M. Stapleton, Cathi Propper, Julia E. Rager
Multiple external stressors are known to have adverse impacts on health and development. Certain groups are more vulnerable and/or more likely to be exposed toenvironmental, psychological, and social stressors simultaneously. Yet, few studies have examined combined exposure to environmental toxicants and psychosocial stress. Here, we integrated environmental chemical exposure data collected using silicone
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BaP/BPDE suppresses homologous recombination repair in human trophoblast cells to induce miscarriage: The roles of lnc-HZ08 Environ. Int. (IF 10.3) Pub Date : 2024-08-23 Weina Chen, Chenglong Ma, Manli Wang, Xinying Huang, Xueyu Chen, Zhongyan Xu, Wenxin Huang, Rong Wang, Zhaodian Zheng, Jing Fang, Yanqiu Shen, Depeng Zhao, Huidong Zhang
Benzo(a)pyrene (BaP) or benzo (a) pyrene 7,8-dihydrodiol-9,10-epoxide (BPDE) exposure causes trophoblast cell dysfunctions and induces miscarriage, which is generally epigenetically regulated. Homologous recombination (HR) repair of DNA double strand break (DSB) plays a crucial role in maintenance of genetic stability and cell normal functions. However, whether BaP/BPDE might suppress HR repair in
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Letter to the Editor, Environment International ‘Available evidence shows adverse symptoms from acute non-thermal RF-EMF exposure’. Comment on: Bosch-Capblanch X et al., The effects of radiofrequency electromagnetic fields exposure on human self-reported symptoms: A systematic review of human experimental studies, Envir Int. vol. 187, May 2024, 108612 Environ. Int. (IF 10.3) Pub Date : 2024-08-23 Michael Bevington
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Transfer of antibiotic resistance genes from soil to rice in paddy field Environ. Int. (IF 10.3) Pub Date : 2024-08-22 Min Xu, Fang Wang, Robert D. Stedtfeld, Yuhao Fu, Leilei Xiang, Hongjie Sheng, Zhongpei Li, Syed A. Hashsham, Xin Jiang, James M. Tiedje
The global spread and distribution of antibiotic resistance genes (ARGs) has received much attention whereas knowledge about the transmission of ARGs from one matrix to another is still insufficient. In this study, the paddy fields fertilized with chemical fertilizer, swine compost, and no fertilizer were investigated to assess the transfer of ARGs from soil to rice. Soil and plant samples were collected
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Corrigendum to “The significance of environmentally bioavailable antimicrobials in driving antimicrobial resistance in soils” [Environ. Int. 190 (2024) 108830] Environ. Int. (IF 10.3) Pub Date : 2024-08-22 Han Yeong Kaw, Jing Yu, Xuejing Ma, Qi Yang, Lizhong Zhu, Wei Wang
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Impact of enniatins and beauvericin on lipid metabolism: Insights from a 3D HepaRG spheroid model Environ. Int. (IF 10.3) Pub Date : 2024-08-22 Qiao Wang, Yan Li, Peihao Hu, Yutao Zhang, Yan Liu, Qing Yang, Lin Xu, Zhiyong Gong, Jiangke Yang, Wen Sun, Xin Liu, Yongning Wu
Emerging mycotoxins enniatins (ENNs) and beauvericin (BEA) pose potential health risks to humans through dietary exposure. However, research into their mechanisms of toxicity is limited, with a lack of comprehensive toxicological data. This study investigates from a hepatic lipid metabolism perspective, establishing a more precise and reliable 3D HepaRG hepatocyte spheroid model as an alternative for
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The fate of antibiotics and antibiotic resistance genes in Large-Scale chicken farm Environments: Preliminary view of the performance of National veterinary Antimicrobial use reduction Action in Guangdong, China Environ. Int. (IF 10.3) Pub Date : 2024-08-21 Yu Pan, Jiaxiong Zeng, Lingxuan Zhang, Jianxin Hu, Haihong Hao, Zhenling Zeng, Yafei Li
In 2018, China implemented the Veterinary Antimicrobial Use Reduction Action to curb the rapid development of antibiotic resistance (AR). However, the AR-related pollutions in animal farms after the reduction policy has been poorly investigated. Here, we performed a comprehensive investigation combining UPLC-MS/MS, metagenomic, and bacterial genomic analyses in eight representative large-scale chicken
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Micro-interfacial behavior of antibiotic-resistant bacteria and antibiotic resistance genes in the soil environment: A review Environ. Int. (IF 10.3) Pub Date : 2024-08-21 Jibao Deng, Wenkang Zhang, Lingyu Zhang, Chao Qin, Hefei Wang, Wanting Ling
Overutilization and misuse of antibiotics in recent decades markedly intensified the rapid proliferation and diffusion of antibiotic resistance genes (ARGs) within the environment, thereby elevating ARGs to the status of a global public health crisis. Recognizing that soil acts as a critical reservoir for ARGs, environmental researchers have made great progress in exploring the sources, distribution
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Effects of seasonal management programs on PM2.5 in Seoul and Beijing using DN-PMF: Collaborative efforts from the Korea-China joint research Environ. Int. (IF 10.3) Pub Date : 2024-08-20 Ilhan Ryoo, Lihong Ren, Gang Li, Tao Zhou, Manhua Wang, Xiaoyang Yang, Taeyeon Kim, Yeonseung Cheong, Songkang Kim, Hyeogki Chae, Kyungmi Lee, Kwon-ho Jeon, Philip K. Hopke, Seung-Muk Yi, Jieun Park
South Korea and China have implemented increasingly stringent mitigation measures to reduce the health risks from PM2.5 exposure, jointly conducting a ground-based air quality observation study in Northeast Asia. Dispersion normalized positive matrix factorization (DN-PMF) was used to identify PM2.5 sources in Seoul and Beijing and assess the effectiveness of the seasonal management programs (SMPs)
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Intergenerational metabolism-disrupting effects of maternal exposure to plasticizer acetyl tributyl citrate (ATBC) Environ. Int. (IF 10.3) Pub Date : 2024-08-20 Danyang Zhang, Weigao Zhang, Hu Liu, Shuxian Huang, Wangchao Huang, Yunfeng Zhu, Xuening Ma, Yugui Xia, Jianfa Zhang, Wei Lu, Da Shao, Dan Weng
Environmental chemicals and pollutants are increasingly recognized for their potential transgenerational effects. Acetyl tributyl citrate (ATBC), a widely used plasticizer substituting di-(2-ethylhexyl) phthalate (DEHP), was identified as an inducer of lipogenesis in male mice by our previous research. This study aimed to investigate the impact of ATBC exposure on the metabolic homeostasis of female
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Simultaneous biomass concentration and subsequent quantitation of multiple infectious disease agents and antimicrobial resistance genes from community wastewater Environ. Int. (IF 10.3) Pub Date : 2024-08-20 Anniina Sarekoski, Anssi Lipponen, Anna-Maria Hokajärvi, Kati Räisänen, Ananda Tiwari, Dafni Paspaliari, Kirsi-Maarit Lehto, Sami Oikarinen, Annamari Heikinheimo, Tarja Pitkänen, the WastPan Study Group
Wastewater-based surveillance (WBS) of infectious disease agents is increasingly seen as a reliable source of population health data. To date, wastewater-based surveillance efforts have largely focused on individual pathogens. However, given that wastewater contains a broad range of pathogens circulating in the population, a more comprehensive approach could enhance its usability. We focused on the
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Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner Environ. Int. (IF 10.3) Pub Date : 2024-08-20 Brian G Oliver, Xiaomin Huang, Rochelle Yarak, Xu Bai, Qi Wang, Razia Zakarya, Karosham D. Reddy, Chantal Donovan, Richard Y. Kim, James Morkaya, Baoming Wang, Yik Lung Chan, Sonia Saad, Alen Faiz, David van Reyk, Alexei Verkhratsky, Chenju Yi, Hui Chen
There is no safe level of air pollution for human health. Traffic-related particulate matter (PM2.5) is a major in-utero toxin, mechanisms of action of which are not fully understood. BALB/c dams were exposed to an Australian level of traffic PM2.5 (5 µg/mouse/day, intranasal, 6 weeks before mating, during gestation and lactation). Male offspring had reduced memory in adulthood, whereas memory was
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Air pollution, traffic noise, mental health, and cognitive development: A multi-exposure longitudinal study of London adolescents in the SCAMP cohort Environ. Int. (IF 10.3) Pub Date : 2024-08-18 Rhiannon Thompson, Gregor Stewart, Tuan Vu, Calvin Jephcote, Shanon Lim, Benjamin Barratt, Rachel B. Smith, Yasmin Bou Karim, Aamirah Mussa, Ian Mudway, Helen L. Fisher, Iroise Dumontheil, Michael S.C. Thomas, John Gulliver, Sean Beevers, Frank J. Kelly, Mireille B. Toledano
There is increasing evidence that air pollution and noise may have detrimental psychological impacts, but there are few studies evaluating adolescents, ground-level ozone exposure, multi-exposure models, or metrics beyond outdoor residential exposure. This study aimed to address these gaps.
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A novel molecular pathway of lipid accumulation in human hepatocytes caused by PFOA and PFOS Environ. Int. (IF 10.3) Pub Date : 2024-08-18 Xiao Gou, Mingming Tian, Lu Yan, Pu Xia, Huimin Ji, Haoyue Tan, Wei Shi, Hongxia Yu, Xiaowei Zhang
Exposed to ubiquitously perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) has been associated with non-alcoholic fatty liver disease (NAFLD), yet the underlying molecular mechanism remains elusive. The extrapolation of empirical studies correlating per- and polyfluoroalkyl substance (PFAS) exposure with NAFLD occurrence to real-life exposure was hindered by the limited availability
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Understanding the molecular pathway of triclosan-induced ADHD-like behaviour: Involvement of the hnRNPA1-PKM2-STAT3 feedback loop Environ. Int. (IF 10.3) Pub Date : 2024-08-17 Chang Shu, He Cui, Yuxuan Peng, Ziyun Wei, Xiao Ni, Linlin Zheng, Jianing Shang, Fu Liu, Jieyu Liu
Triclosan (TCS) is an environmental pollutant. In recent years, there has been increasing level of concern regarding the potential toxicity of TCS in animals and humans, especially its effects on the nervous system. However, whether TCS induces ADHD-like behaviour and the mechanism by which it affects neural function are unclear. The impact of 60 days of continuous exposure to TCS on the behaviour
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Migration and accumulation of microplastics in soil-plant systems mediated by symbiotic microorganisms and their ecological effects Environ. Int. (IF 10.3) Pub Date : 2024-08-17 Xinru Li, Feng Shi, Min Zhou, Fengchang Wu, Hailei Su, Xuesong Liu, Yuan Wei, Fanfan Wang
The coexistence of microorganisms in complex soil environments greatly affects the environmental behavior and ecological effects of microplastics (MPs). However, relevant studies are sparse, and internal mechanisms remain unclear. Herein, arbuscular mycorrhizal fungi (AMF), a common symbiotic microorganism in the soil–plant system, was proved to significantly affect MPs absorption and migration with
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Soil keystone viruses are regulators of ecosystem multifunctionality Environ. Int. (IF 10.3) Pub Date : 2024-08-17 Pu Jia, Jie-Liang Liang, Jing-li Lu, Sheng-ji Zhong, Tian Xiong, Shi-wei Feng, Yutao Wang, Zhuo-hui Wu, Xin-zhu Yi, Shao-ming Gao, Jin Zheng, Ping Wen, Fenglin Li, Yanying Li, Bin Liao, Wen-sheng Shu, Jin-tian Li
Ecosystem multifunctionality reflects the capacity of ecosystems to simultaneously maintain multiple functions which are essential bases for human sustainable development. Whereas viruses are a major component of the soil microbiome that drive ecosystem functions across biomes, the relationships between soil viral diversity and ecosystem multifunctionality remain under-studied. To address this critical
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Environmental risks in swine biogas slurry-irrigated soils: A comprehensive analysis of antibiotic residues, resistome, and bacterial pathogens Environ. Int. (IF 10.3) Pub Date : 2024-08-16 Jie-Yi Zeng, Miaoling Meng, Lin Qi, Yaying Li, Huaiying Yao
Simple anaerobic digestion is insufficient to completely remove residual parent antibiotics and antibiotic resistance genes (ARGs) from animal manure. ARG prevalence in swine biogas slurry-irrigated soils threatens human health. However, comprehensive analysis of antibiotic residues, high-resolution resistance gene profiles, and pathogenic microbiomes in biogas slurry-irrigated soils is very limited
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Aged fragmented-polypropylene microplastics induced ageing statues-dependent bioenergetic imbalance and reductive stress: In vivo and liver organoids-based in vitro study Environ. Int. (IF 10.3) Pub Date : 2024-08-15 Wei Cheng, Hange Chen, Yue Zhou, Yifei You, Dong Lei, Yan Li, Yan Feng, Yan Wang
Ageing is a nature process of microplastics that occurrs daily, and human beings are inevitably exposed to aged microplastics. However, a systematic understanding of ageing status and its toxic effect is currently still lacking. In this study, plastic cup lids-originated polypropylene (PP) microplastics were UV-photoaged until the carbonyl index (CI), a canonical indicator for plastic ageing, achieved
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Extreme temperatures, PM2.5 and trajectories of impaired thyroid hormone sensitivity: A longitudinal study of patients with schizophrenia Environ. Int. (IF 10.3) Pub Date : 2024-08-15 Jintao Liu, Rong Song, Rubing Pan, Weizhuo Yi, Xiaoyu Jin, Jian Song, Jian Cheng, Xulai Zhang, Hong Su
The climate change scenario has witnessed an increase in extreme temperature events (ETEs), including heat waves and cold spells, and a heightened occurrence of compounding with fine particulate matter (PM2.5). However, the impact of this phenomenon on the sensitivity to thyroid hormones (THs) in humans is unclear, especially in a group as specific as schizophrenia.