Background In recent years, residential green and availability of neighbourhood green spaces came into focus as a potential means to reduce transportation noise annoyance. Literature suggests that various characteristics of residential green may play a role, namely, greenness of the residential areas as quantified by the normalized difference vegetation index (NDVI), visible vegetation from home, and

Coastal flood impact assessments are important tools for risk management and are performed by combining the hazard component with the vulnerability of exposed assets, to quantify consequences (or impacts) in terms of relative or absolute (e.g. financial) damage. The process generates uncertainties that should be taken into account for the correct representation of the consequences of floods. This study

Background There is growing public awareness regarding the health effects of indoor nanoscale particulate matter (INPM) since people spend the majority of their time indoors. INPM could have a direct entry route into the brain via the axons of the olfactory nerve and migrating across the blood-brain barrier (BBB). Using animals to explore this possibility is not a reliable method to fully demonstrate

The exposome concept refers to the totality of exposures from a variety of external and internal sources including chemical agents, biological agents, or radiation, from conception onward, over a complete lifetime. It encompasses also “psychosocial components” including the impact of social relations and socio-economic position on health. In this review we provide examples of recent contributions from

Background A large body of evidence has shown a link between arsenic exposure and diabetes, but the underlying mechanisms have not yet been clarified. Objective We explored the association between arsenic exposure and the reduction of skeletal muscle mass as a potential mechanism of insulin resistance for developing arsenic-related hyperglycemia. Methods A total of 581 subjects were recruited from

Background Studies evaluating the role of long-term exposure to fine particulate matter (PM2.5) on chronic obstructive pulmonary disease (COPD) development showed inconsistent results and were limited to Western countries. We aimed to determine the association between long-term exposure to PM2.5 and COPD development in metropolitan cities in Korea, which have higher PM2.5 levels than those in Western

Polycyclic aromatic compounds (PACs), including polycyclic aromatic hydrocarbons (PAHs) and oxygenated PAHs (oxy-PAHs), are common environmental pollutants known to cause health effects in humans and wild-life. In particular, vertebrate cardiovascular development and function are sensitive to PACs. However, the interactive effects of PAHs and oxy-PAHs on cardiovascular endpoints have not been well

Aim To determine the associations between outdoor air pollution and hospital outpatient visits for mental disorders in China. Methods We obtained data of 111,842 hospital outpatient visits for mental disorders from the largest hospitals of 13 cities, China, between January 01, 2013 and December 31, 2015. We collected air pollutant data including particulate matter ≤2.5 µm in diameter (PM2.5), particulate

Background Fine particulate matter (with aerodynamic diameter ≤2.5 µm, PM2.5) causes huge disease burden worldwide. However, evidence is still inadequate and inconsistent on the relationships between PM2.5 constituents and mortality, especially in low resource settings. Objectives To evaluate the impact of PM2.5 constituents on cause-specific mortality in China. Methods We obtained daily mortality

The anoxic-oxic (A/O) wastewater treatment process that is widely used in pig farms in China is an important repository for antibiotic resistance genes (ARGs). However, the distribution of ARGs and their hosts in the A/O process has not been well characterized. In this study, the wastewaters in the anoxic and oxic tanks for A/O processes were collected from 38 pig farms. The concentrations of 20 subtypes

This paper describes the use of multiple models and model averaging for considering dose–response uncertainties when extrapolating low-dose risk from studies of populations with high levels of exposure. The model averaging approach we applied builds upon innovative methods developed by the U.S. Food and Drug Administration (FDA), principally through the relaxing of model constraints. The relaxing of

Harbour porpoise (Phocoena phocoena), the only resident cetacean species of the Baltic Sea is formed of two subpopulations populations, occurring in the western Baltic, Belt Seas and Kattegat and the Baltic Proper, respectively. Harbour porpoises throughout these areas are exposed to a large number of human activities causing direct and indirect effects on individuals, that might also harm this species

The biodiversity hypothesis that contact with natural environments (e.g. native vegetation) and biodiversity, through the influence of environmental microbes, may be beneficial for human commensal microbiota has been insufficiently tested. We aimed to study the association between living near natural environments in the urban context, and gut microbiota diversity and composition in young infants. Based

Background Cadmium is a toxic heavy metal that has been implicated in breast cancer etiology, albeit with inconsistent results. Objective To investigate the shape of the relation between cadmium exposure and breast cancer incidence and mortality in cohort studies. Data sources Following a literature search through April 14, 2020, we carried out a systematic review and dose-response meta-analysis to

Background Preterm birth is a major determinant of adverse health consequences, and early term births are also associated with increased risk of various outcomes. In light of climate change, the effect of ambient temperature on earlier delivery is an important factor to consider. Several studies have focused on associations of ambient air temperature (Ta) on preterm birth, but few have examined associations

Background Air pollution exposure during pregnancy is an important environmental health issue. Epigenetics mediate the effects of prenatal exposure and could increase disease predisposition in later life. The oncogenic miR-17/92 cluster is involved in normal development and disease. Objectives Here, for the first time the potential prenatal effects of particulate matter with a diameter<2.5 μm (PM2

Background Animal studies suggest that organophosphorus pesticides (OPs) may be environmental obesogens. While prenatal OP exposures have been associated with altered infant glucose metabolism, associations with pediatric adiposity remain unknown. Methods We summed concentrations of three dimethylphosphate (∑DMP) and three diethylphosphate (∑DEP) metabolites of OPs measured in third trimester spot

Objective Arsenic is a known childhood neurotoxicant, but its neurotoxicity at low exposure levels is still not well established. The aim of our cross-sectional study was to test the association between low-level arsenic exposure and executive functions (EF) among children in Montevideo. We also assessed effect modification by arsenic methylation capacity, a susceptibility factor for the health effects

Satellite observations show that the rapid urbanization and emergence of megacities with 10 million or more residents have raised PM2.5 concentrations across the globe during the past few decades. This study examines PM2.5 dynamics for the 33 cities included on the UN list of megacities published in 2018. These megacities were classified into densely (>1500 residents per km2), moderately (300–1500

Background Dyslipidemia is a major risk factor for cardiovascular disease. Several studies have explored the associations of greenness with blood lipids. However, the evidence is still limited and mixed, especially in rural areas. Methods From May to September 2016, we recruited 4735 Uyghur adults from rural areas of northwestern China. We measured levels of total cholesterol (TC), triglycerides (TG)

Microbial taxa within complex ecological networks can be classified by their universal roles based on their level of connectivity with other taxa. Highly connected taxa within an ecological network (kinless hubs) are theoretically expected to support higher levels of ecosystem functions than less connected taxa (peripherals). Empirical evidence of the role of kinless hubs in regulating the functional

Background Phthalates are a group of heavily produced endocrine disruptors that are widely used in personal care products, food packaging, building materials, and medical device. Few epidemiological studies have examined the effect of repeated prenatal exposure to multiple phthalates on preschooler cognitive development. Objectives This study aimed to examine the association between prenatal phthalate

Background In countries where air pollution stations are unavailable or scarce, station measurements from other countries and atmospheric remote sensing could jointly provide information to estimate ambient air quality at a sufficiently fine resolution to study the relationship between air pollution exposure and health. Predicting NO2 concentration globally with sufficient spatial and temporal resolution

Background Ambient air pollution has been linked to the development of gestational diabetes mellitus (GDM). However, previous studies provided inconsistent findings and no study has examined the effects of complex chemical constituents of the particular matter on GDM, especially in developing countries. Therefore, we aim to investigate the associations of exposure to PM2.5 (particular matter ≤ 2.5 μm)

Background Environmental health research has reported mixed findings on the associations between prenatal exposure to phthalates and parent-ratings of child behavioral problems. Objective We examined the consistency of the associations between prenatal urinary phthalate concentrations and child behavior scores across two standardized instruments – the Behavior Assessment System for Children-Second

Background Recent studies suggest that greater exposure to natural vegetation, or “green space” is associated with lower diabetes risk, possibly through increasing physical activity. However, there is limited research on green space and insulin resistance in youth. We hypothesized greater green space at early-life sensitive time periods would be associated with lower insulin resistance in youth. Methods

Background Few studies have examined the risk of long-term exposure to source-specific airborne pollutants on incidence of cerebrovascular and cardiovascular events. Objectives We aimed to estimate the effect of long-term exposure to source-specific air pollution and particulate matter (PM) components on incidence of stroke, coronary heart disease (CHD), and total cardiovascular events (CVE) in the

Exposure to mixtures of endocrine disrupting chemicals may contribute to the rising incidence of hormone-related diseases in humans. Real-life mixtures are complex, comprised of chemicals with mixed modes of action, and essential knowledge is often lacking on how to group such chemicals into cumulative assessment groups, which is an essential prerequisite to conduct a chemical mixture risk assessment

Ambient air pollution has been linked to stroke, but few studies have examined in detail stroke subtypes and confounding by road traffic noise, which was recently associated with stroke. Here we examined the association between long-term exposure to air pollution and incidence of stroke (overall, ischemic, hemorrhagic), adjusting for road traffic noise. In a nationwide Danish Nurse Cohort consisting

Although several studies have reported that social isolation is one of the important health risk factors in the elderly population living in urban areas, its effects on vulnerability to heatwaves have been studied relatively less than climatic and other socio-economic factors. Thus, we investigated the association between social isolation levels and heatwave-related mortality risk in the elderly population

In this research, a novel chitosan (CS)–vanadium-titanium-magnetite (VTM) composite was designed and synthesized. The interaction between CS-VTM and Congo red (CR) dye conformed to a pseudo-second-order model to support the potent involvement of chemisorption. The effects of adsorbent dosage, reaction temperature, and initial solution pH on adsorption of CR were investigated. Approximately 99.1% of

Background An association between maternal exposure to air pollution and the birth weight distribution has been reported, but the extent to which this relationship varies according to socioeconomic status (SES) is unknown. This study examined the relationship using the data from a Korean birth cohort. Methods Data for singleton births in Seoul from 2007 to 2017 (n = 1739) were analyzed. Maternal exposures

The Baltic/Wadden Sea Flyway of common eiders has declined over the past three decades. Multiple factors such as contaminant exposure, global warming, hunting, white-tailed eagle predation, decreased agricultural eutrophication and infectious diseases have been suggested to explain the decline. We collected information on body mass, mercury (Hg) concentration, biochemistry and untargeted metabolomics

This study aimed to investigate the occurrences of a suite of thirty-one organophosphate tri-esters (tri-OPEs) and six di-esters (di-OPEs) in house dust collected from Adelaide, South Australia. The results demonstrate ubiquitous presence of most OPEs in Adelaide house dust, with median concentration of 40,200 and 5260 ng/g dry weight for ∑tri-OPEs and ∑di-OPEs, respectively. A number of emerging OPEs

Personal care and consumer products are extensively used and contain various chemicals that are recognized as endocrine disrupting chemicals. Few epidemiological studies measured the associations of these chemicals and metabolites, especially phenols, with bone health. We measured the associations between nine urinary phenol biomarkers and BMD and the subsequent prevalence of osteopenia/osteoporosis

Breast cancer (BC) is a common cancer in women worldwide; however, the incidence of BC is increasing in younger women, possibly associated with the environment. Perfluoroalkyl substances (PFAS) are one of endocrine disruptors that accumulate in environment and impact human health. This study aimed to investigate whether the PFAS and BC are associated. We enrolled 120 BCE patients and 119 controls at

The Christiansø colony of common eiders (Somateria mollissima) in the central Baltic Sea were exposed to high levels of Pb during the 2018 breeding season that were not present in 2017. Due to these high Pb blood levels, the present study investigated possible Pb sources and Pb dynamics within this vulnerable colony. We analyzed body mass and lead isotopic ratios (Pb-IRs) in blood taken from the same

Apex predators are characterized by high levels of biomagnifying organohalogenated contaminants (OHCs) which have been found to induce detrimental health effects in wildlife, such as immune system impairment. The leukocyte coping capacity (LCC) assay is a functional real-time measure of an innate immune response essential in pathogen resistance, known as the respiratory burst. The current study suggests

Aromatic matters are widely present in wastewater, especially industrial wastewater, and may lead to a high abundance of antibiotic resistance genes (ARGs) in wastewater treatment bioreactors and stimulate horizontal transfers of ARGs. Here, we investigated a practical approach that applying ozone pretreatment to mitigate ARGs in bioreactors treating wastewater containing a typical aromatic pollutant

Biotransport is often associated with migration patterns of species, including large, anadromous salmonids. Several studies have reported biotransport of persistent organic pollutants in the Northern Hemisphere, but there is no published information on biotransport ocurring south of the equator. Chile’s Patagonia is one of the last largely intact natural areas in the world. The objective of this study

Zearalenone is a widespread mycotoxin with high estrogenic activity. This study aimed to characterize the exposure of ZEN in a Chinese population during harvest season in 2016. Exposure to ZEN was measured using both duplicate diet method and human biomonitoring approaches. Duplicate diet samples from 199 individuals (4–80 years old) and their following morning urine samples were collected and analyzed