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Probing the salivary proteome for prognostic biomarkers in response to non‐surgical periodontal therapy J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-25 Angelika Silbereisen, Kai Bao, Witold Wolski, Paolo Nanni, Laura Kunz, Beral Afacan, Gülnur Emingil, Nagihan Bostanci
AimThis prospective study investigated the salivary proteome before and after periodontal therapy.Materials and MethodsTen systemically healthy, non‐smoking, stage III, grade C periodontitis patients underwent non‐surgical periodontal treatment. Full‐mouth periodontal parameters were measured, and saliva (n = 30) collected pre‐ (T0), and one (T1) and six (T6) months post‐treatment. The proteome was
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Domains, competences and learning outcomes for undergraduate education in periodontology J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-24 Elena Figuero, Mervi Gürsoy, Virginie Monnet‐Corti, Margarita Iniesta, Angeline Antezack, Ines Kapferer‐Seebacher, Christian Graetz, Yuval Vered, Andreas Stavropoulos, Asaf Wilensky, Peter Eickholz, Mariano Sanz
AimThis review is intended to adapt the current conceptual framework in dental education based on four domains to propose a set of competences, learning outcomes and methods of teaching, learning and assessment for undergraduate education in periodontology.ReviewBased on the current framework of competences and learning outcomes recommended by the Association for Dental Education in Europe (ADEE),
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Effects of intermittent fasting on periodontal inflammation and subgingival microbiota J. Periodontol. (IF 4.3) Pub Date : 2024-04-24 Ronaldo Lira‐Junior, Micheál Mac Aogáin, Eva Crncalo, Neda Rajamand Ekberg, Sanjay H. Chotirmall, Sven Pettersson, Anders Gustafsson, Kerstin Brismar, Nagihan Bostanci
BackgroundStudies on the impact of intermittent fasting on periodontal health are still scarce. Thus, this study evaluated the effects of long‐term intermittent fasting on periodontal health and the subgingival microbiota.MethodsThis pilot study was part of a nonrandomized controlled trial. Overweight/obese participants (n = 14) entered an intermittent fasting program, specifically the 5:2 diet, in
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Transcriptomic and cellular decoding of scaffolds-induced suture mesenchyme regeneration Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-23 Jiayi Wu, Feifei Li, Peng Yu, Changhao Yu, Chuyi Han, Yitian Wang, Fanyuan Yu, Ling Ye
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Impact of autologous platelet concentrates on the osseointegration of dental implants Periodontol. 2000 (IF 18.6) Pub Date : 2024-04-22 Sašo Ivanovski, Ryan S. B. Lee, Tulio Fernandez‐Medina, Nelson Pinto, Catherine Andrade, Marc Quirynen
Osseointegration is defined as the direct deposition of bone onto biomaterial devices, most commonly composed from titanium, for the purpose of anchoring dental prostheses. The use of autologous platelet concentrates (APC) has the potential to enhance this process by modifying the interface between the host and the surface of the titanium implant. The rationale is to modify the implant surface and
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The distance of insertion points from wound margins in interrupted and vertical mattress sutures influences the tensile load capacity: An in vitro experimental study Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-22 Seungho Jeong, Won‐Ho Lee, Kyu‐Jin Hong, Franz Josef Strauss, Jung‐Seok Lee
AimTo determine the tensile load capacity (TLC) and the tearing characteristics for interrupted and vertical mattress sutures with different insertion points from the wound margin, and the effect of the bite size when using vertical mattress sutures.Materials and MethodsA total of 120 gingiva and lining mucosa samples obtained from pig jaws were divided into groups according to the suturing technique
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The role and impact of viruses on cancer development Periodontol. 2000 (IF 18.6) Pub Date : 2024-04-20 Adolfo Contreras, Sandra Amaya Sánchez, Carolina Rodríguez‐Medina, Javier Enrique Botero
This review focuses on three major aspects of oncoviruses' role in cancer development. To begin, we discuss their geographic distribution, revealing that seven oncoviruses cause 20% of all human cancers worldwide. Second, we investigate the primary carcinogenic mechanisms, looking at how these oncogenic viruses can induce cellular transformation, angiogenesis, and local and systemic inflammation. Finally
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The role of acquired host immunity in periodontal diseases Periodontol. 2000 (IF 18.6) Pub Date : 2024-04-20 Denis F. Kinane, David F. Lappin, Shauna Culshaw
The aim of this narrative review is to relate the contribution of European researchers to the complex topic of the host immune system in periodontal disease, focusing on acquired immunity. Other chapters in this volume will address the genetics and autoantibody responses and other forms of immunity to periodontal disease. While the contribution of European authors is the focus, global literature is
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Enhanced control of periodontitis by an artificial intelligence‐enabled multimodal‐sensing toothbrush and targeted mHealth micromessages: A randomized trial J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-17 Yuan Li, Xinyu Wu, Min Liu, Ke Deng, Annamaria Tullini, Xiao Zhang, Junyu Shi, Hongchang Lai, Maurizio S. Tonetti
AimTreatment of periodontitis, a chronic inflammatory disease driven by biofilm dysbiosis, remains challenging due to patients' poor performance and adherence to the necessary oral hygiene procedures. Novel, artificial intelligence‐enabled multimodal‐sensing toothbrushes (AI‐MST) can guide patients' oral hygiene practices in real‐time and transmit valuable data to clinicians, thus enabling effective
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Accuracy of template‐based guided dental implant placement—An in vitro comparison of different manufacturing methods Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-17 Aura Sium‐Abel, Ludger Keilig, Istabrak Dörsam, Christoph Bourauel
ObjectivesThis study investigates effects of surgical guide manufacturing process on 3D transfer accuracy of planned dental implant position, using three production methods: additive 3D‐printed (3DF), subtractive milled (MF), and analog laboratory fabricated templates (LF).Material and MethodsImplant position for a single‐tooth gap (#26) planned digitally. 3DF and MF templates were designed digitally
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Inter and intra‐operator reliability of Lekholm and Zarb classification and proposal of a novel radiomic data‐driven clustering for qualitative assessment of edentulous alveolar ridges Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-17 Giuseppe Troiano, Antonio Rapani, Francesco Fanelli, Federico Berton, Marino Caroprese, Teresa Lombardi, Khrystyna Zhurakivska, Claudio Stacchi
ObjectivesThe present study was conducted to evaluate the reproducibility of Lekholm and Zarb classification system (L&Z) for bone quality assessment of edentulous alveolar ridges and to investigate the potential of a data‐driven approach for bone quality classification.Materials and MethodsTwenty‐six expert clinicians were asked to classify 110 CBCT cross‐sections according to L&Z classification (T0)
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Expert consensus on pediatric orthodontic therapies of malocclusions in children Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-16 Chenchen Zhou, Peipei Duan, Hong He, Jinlin Song, Min Hu, Yuehua Liu, Yan Liu, Jie Guo, Fang Jin, Yang Cao, Lingyong Jiang, Qingsong Ye, Min Zhu, Beizhan Jiang, Wenhua Ruan, Xiao Yuan, Huang Li, Rui Zou, Yulou Tian, Li Gao, Rui Shu, Jianwei Chen, Renkai Liu, Shujuan Zou, Xiaobing Li
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Single cell analysis unveils B cell-dominated immune subtypes in HNSCC for enhanced prognostic and therapeutic stratification Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-16 Kang Li, Caihua Zhang, Ruoxing Zhou, Maosheng Cheng, Rongsong Ling, Gan Xiong, Jieyi Ma, Yan Zhu, Shuang Chen, Jie Chen, Demeng Chen, Liang Peng
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Tetrahedral framework nucleic acids/hyaluronic acid-methacrylic anhydride hybrid hydrogel with antimicrobial and anti-inflammatory properties for infected wound healing Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-16 Cai Qi, Qiang Sun, Dexuan Xiao, Mei Zhang, Shaojingya Gao, Bin Guo, Yunfeng Lin
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Tailored apoptotic vesicles promote bone regeneration by releasing the osteoinductive brake Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-16 Yawen Cheng, Yuan Zhu, Yaoshan Liu, Xuenan Liu, Yanan Ding, Deli Li, Xiao Zhang, Yunsong Liu
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Periodontitis, Dental Procedures, and Young-Onset Cryptogenic Stroke J. Dent. Res. (IF 7.6) Pub Date : 2024-04-16 J. Leskelä, J. Putaala, N. Martinez-Majander, L. Tulkki, M. Manzoor, S. Zaric, P. Ylikotila, R. Lautamäki, A. Saraste, S. Suihko, E. Könönen, J. Sinisalo, P.J. Pussinen, S. Paju
Periodontitis is associated with an increased risk of ischemic stroke, and the risk may be particularly high among young people with unexplained stroke etiology. Thus, we investigated in a case-control study whether periodontitis or recent invasive dental treatments are associated with young-onset cryptogenic ischemic stroke (CIS). We enrolled participants from a multicenter case-control SECRETO study
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Tongue-Coating Microbial and Metabolic Characteristics in Halitosis J. Dent. Res. (IF 7.6) Pub Date : 2024-04-16 Y. Zhang, K.L. Lo, A.N. Liman, X.P. Feng, W. Ye
Halitosis is a common oral condition, which leads to social embarrassment and affects quality of life. Cumulative evidence has suggested the association of tongue-coating microbiome with the development of intraoral halitosis. The dynamic variations of tongue-coating microbiota and metabolites in halitosis have not been fully elucidated. Therefore, the present study aimed to determine the tongue-coating
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Metabolic profiling of peri‐implant crevicular fluid in peri‐implantitis Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-16 Lu Song, Hongye Lu, Jimin Jiang, Antian Xu, Yanli Huang, Jia‐Ping Huang, Pei‐Hui Ding, Fuming He
ObjectsThis study aims to explore the etiology of peri‐implantitis by comparing the metabolic profiles in peri‐implant crevicular fluid (PICF) from patients with healthy implants (PH) and those with peri‐implantitis (PI).Materials and MethodsFifty‐six patients were enrolled in this cross‐sectional study. PICF samples were collected and analyzed using both non‐targeted and targeted metabolomics approaches
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Spatiotemporal Evolution of Developing Palate in Mice J. Dent. Res. (IF 7.6) Pub Date : 2024-04-15 B. Wang, Z. Zhang, J. Zhao, Y. Ma, Y. Wang, N. Yin, T. Song
The intricate formation of the palate involves a series of complex events, yet its mechanistic basis remains uncertain. To explore major cell populations in the palate and their roles during development, we constructed a spatiotemporal transcription landscape of palatal cells. Palate samples from C57BL/6 J mice at embryonic days 12.5 (E12.5), 14.5 (E14.5), and 16.5 (E16.5) underwent single-cell RNA
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Strategies for Improving Impaired Osseointegration in Compromised Animal Models J. Dent. Res. (IF 7.6) Pub Date : 2024-04-15 J. Deng, C. Van Duyn, D. J. Cohen, Z. Schwartz, B. D. Boyan
Implant osseointegration is reduced in patients with systemic conditions that compromise bone quality, such as osteoporosis, disuse syndrome, and type 2 diabetes. Studies using rodent models designed to mimic these compromised conditions demonstrated reduced bone-to-implant contact (BIC) or a decline in bone mineral density. These adverse effects are a consequence of disrupted intercellular communication
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The adjunctive effect of polydeoxyribonucleotide on bone formation in alveolar ridge preservation: A pre‐clinical in vivo study J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-13 Young‐Chang Ko, Jungwon Lee, Istvan Urban, Yang‐Jo Seol, Yong‐Moo Lee, Ki‐Tae Koo
AimThis study investigated the adjunctive effect of polydeoxyribonucleotide (PDRN) on bone formation in alveolar ridge preservation (ARP) sockets.Materials and MethodsBoth mandibular second, third and fourth premolars of eight beagle dogs were randomly divided into ARP and ARP/PDRN groups. Following tooth extraction, ARP procedures were conducted using collagenized alloplastic graft material and bilayer
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Impact of digital technologies on implant surgery in fully edentulous patients: A scoping review Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-13 Alejandro Lanis, Juan Francisco Peña‐Cardelles, William Matthew Negreiros, Adam Hamilton, German O. Gallucci
BackgroundFor over three decades, digital technologies have been used in Implant Dentistry, beginning with the introduction of planning software for Static Computer‐Assisted Implant Surgery (S‐CAIS). During this time, this field has witnessed the emergence of diverse methodologies and a proliferation of technological advancements. Today, S‐CAIS is a widely adopted procedure for the placement of dental
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The Alcohol Harm Paradox in Periodontitis J. Dent. Res. (IF 7.6) Pub Date : 2024-04-12 L.M. Oliveira, F.B. Zanatta, S.A. Costa, T.R. Pelissari, S.E. Baumeister, F.F. Demarco, G.G. Nascimento
Individuals of lower socioeconomic position (SEP) experience a greater rate of alcohol-related harms, yet they consume equal or lower amounts of alcohol than higher-SEP individuals. This phenomenon, called the “alcohol harm paradox” (AHP), gained attention recently, and different mechanisms have been proposed to explain it. Since both SEP and alcohol have been suggested to be associated with periodontitis
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Patient awareness of the association between periodontal and systemic diseases in an academic setting J. Periodontol. (IF 4.3) Pub Date : 2024-04-12 William Carter, Tamanna Tiwari, Satheesh Elangovan, Lonnie Johnson, Karo Parsegian, Sangeetha Chandrasekaran
BackgroundPeriodontal diseases (PD) have been increasingly associated with several systemic conditions such as cardiovascular disease (CVD), diabetes mellitus (DM), rheumatoid arthritis (RA), and Alzheimer's disease (AD). This study aimed to gain insight into patients’ awareness of the association between PD and systemic diseases.MethodsA survey was developed to analyze patient awareness of the association
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How to explain the beneficial effects of platelet‐rich plasma Periodontol. 2000 (IF 18.6) Pub Date : 2024-04-11 Reinhard Gruber
Platelet‐rich plasma (PRP) is the platelet and leukocyte‐containing plasmatic fraction of anticoagulated autologous blood. While evidence supporting the clinical use of PRP in dentistry is low, PRP is widely used in sports medicine, orthopedics, and dermatology. Its beneficial activity is commonly attributed to the growth factors released from platelets accumulating in PRP; however, evidence is indirect
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Microstructural, Micromechanical Atlas of the Temporomandibular Joint Disc J. Dent. Res. (IF 7.6) Pub Date : 2024-04-10 N. Jiang, P. Tan, Y. Sun, J. Zhou, R. Ren, Z. Li, S. Zhu
The temporomandibular joint (TMJ) disc is mainly composed of collagen, with its arrangement responding to efficient stress distribution. However, microstructural and micromechanical transformations of the TMJ disc under resting, functional, and pathological conditions remain unclear. To address this, our study presents a high-resolution microstructural and mechanical atlas of the porcine TMJ disc.
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Clinical performance and risk factors of all‐ceramic screw‐retained implant crowns in the posterior region based on a retrospective investigation Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-10 Tobias Graf, Alina Lyko, Iulia Dahmer, Michael Stimmelmayr, Horst Dieterich, Hans Aggstaller, Jan‐Frederik Güth
ObjectivesClinical data on all‐ceramic screw‐retained implant crowns (SICs) luted on titanium base abutments (TBAs) over more than 3 years are sparse. This study aimed to evaluate the clinical performance and potential risk factors for these restorations.Materials and MethodsAnalysis took place based on the medical patient‐records of three dental offices. Implant survival and prosthetic complications
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Understanding exosomes: Part 2—Emerging leaders in regenerative medicine Periodontol. 2000 (IF 18.6) Pub Date : 2024-04-09 Richard J. Miron, Nathan E. Estrin, Anton Sculean, Yufeng Zhang
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells with the ability to communicate with other tissues and cell types over long distances. Their use in regenerative medicine has gained tremendous momentum recently due to their ability to be utilized as therapeutic options for a wide array of diseases/conditions. Over 5000 publications are currently being published
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Digital planning and bone regenerative technologies: A narrative review Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-09 Grazia Tommasato, Sergio Piano, Paolo Casentini, Luca De Stavola, Matteo Chiapasco
ObjectivesThe aim of this narrative review was to explore the application of digital technologies (DT) for the simplification and improvement of bone augmentation procedures in advanced implant dentistry.Material and methodsA search on electronic databases was performed to identify systematic reviews, meta‐analyses, randomized and non‐randomized controlled trials, prospective/retrospective case series
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The evolution of robotics: research and application progress of dental implant robotic systems Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-04-08 Chen Liu, Yuchen Liu, Rui Xie, Zhiwen Li, Shizhu Bai, Yimin Zhao
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A Polygenic Score Predicts Caries Experience in Elderly Swedish Adults J. Dent. Res. (IF 7.6) Pub Date : 2024-04-08 N. Fries, S. Haworth, J.R. Shaffer, A. Esberg, K. Divaris, M.L. Marazita, I. Johansson
Caries is a partially heritable disease, raising the possibility that a polygenic score (PS, a summary of an individual’s genetic propensity for disease) might be a useful tool for risk assessment. To date, PS for some diseases have shown clinical utility, although no PS for caries has been evaluated. The objective of the study was to test whether a PS for caries is associated with disease experience
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Oral–Gut–Estrobolome Axis May Exert a Selective Impact on Oral Cancer J. Dent. Res. (IF 7.6) Pub Date : 2024-04-08 M. Tatullo, J. Nor, G. Orrù, A. Piattelli, E. Cascardi, G. Spagnuolo
A subset of bacterial species that holds genes encoding for β-glucuronidase and β-galactosidase, enzymes involved in the metabolism of conjugated estrogens, is called the “estrobolome.” There is an emerging interest embracing this concept, as it may exert a selective impact on a number of pathologies, including oral cancer. Although the estrobolome bacteria are typically part of the gut microbiota
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Accuracy of open‐sleeved vs. closed‐sleeved static computer‐assisted implant systems in immediate maxillary molar implant placement: An in vitro study Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-08 Zhaozhao Chen, Junying Li, Chen Xuan Wei, Gustavo Mendonca, Hom‐Lay Wang
ObjectivesThe objective of this study is (1) to compare the accuracy of an open‐sleeved static computer‐assisted implant system (sCAIS) with a closed‐sleeve sCAIS and free‐hand approach in immediate implant placement (IIP) of maxillary molar sites and (2) to investigate the influence of socket morphology on these approaches.Materials and MethodsNinety partially edentulous duplicated maxillary models
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Five decades of research on immediate implant therapy: A modern bibliometric network analysis via Altmetric and level of evidence mapping Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-08 Hamoun Sabri, Neshatafarin Manouchehri, Lorenzo Tavelli, Joseph Y. K. Kan, Hom‐Lay Wang, Shayan Barootchi
AimTo conduct a bibliometric network analysis to explore the research landscape of immediate implant placement (IIP) and provide insights into its trends and contributors.Materials and MethodsThe Scopus database was utilized as the bibliographic source, and a search strategy was implemented to identify relevant research articles. Various bibliometric parameters were extracted, including publication
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UiO-66/AgNPs Coating for Dental Implants in Preventing Bacterial Infections J. Dent. Res. (IF 7.6) Pub Date : 2024-04-06 C. Yu, Y. Yu, Y. Lu, K. Quan, Z. Mao, Y. Zheng, L. Qin, D. Xia
Titanium (Ti)–based biomaterials lack inherent antimicrobial activities, and the dental plaque formed on the implant surface is one of the main risk factors for implant infections. Construction of an antibacterial surface can effectively prevent implant infections and enhance implant success. Silver nanoparticles (AgNPs) exhibit broad antibacterial activity and a low tendency to induce drug resistance
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Zinc- and Fluoride-Releasing Bioactive Glass as a Novel Bone Substitute J. Dent. Res. (IF 7.6) Pub Date : 2024-04-06 T. Kondo, K. Otake, H. Kakinuma, Y. Sato, S. Ambo, H. Egusa
Bioglass 45S5, a silica-based glass, has pioneered a new field of biomaterials. Bioglass 45S5 promotes mineralization through calcium ion release and is widely used in the dental field, including toothpaste formulations. However, the use of Bioglass 45S5 for bone grafting is limited owing to the induction of inflammation, as well as reduced degradation and ion release. Phosphate-based glasses exhibit
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Immediate versus delayed implant placement of novel fully tapered tissue‐level implants – A retrospective multicenter clinical study Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-04 Eik Schiegnitz, Keyvan Sagheb, Leila Raahimi, Jochem König, Adriano Azaripour, Bilal Al‐Nawas
ObjectivesTo compare the clinical and radiological outcomes of novel fully tapered tissue‐level implants in immediate implant placement (type 1) versus late implant placement (type 4) for the first time.Materials and MethodsFor this clinical study, 318 fully tapered tissue‐level implants in 65 patients were inserted immediately (n = 68 implants) or late (n = 250 implants) in two different centers.
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Correction to “Akkermansia muciniphila reduces Porphyromonas gingivalis‐induced inflammation and periodontal bone destruction” J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-03
Huck, O, Mulhall, H, Rubin, G, et al. Akkermansia muciniphila reduces Porphyromonas gingivalis-induced inflammation and periodontal bone destruction. J Clin Periodontol. 2020; 47: 202–212. https://doi.org/10.1111/jcpe.13214 Concerns were raised by a third party regarding the appearance of Figure 2, suggesting that the A and D subpanels show identical images for the “H&E Control” and overlapping field
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Correction to “Kava‐241 reduced periodontal destruction in a collagen antibody primed Porphyromonas gingivalis model of periodontitis” J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-03
Alshammari, A, Patel, J, Al-Hashemi, J, Cai, B, Panek, J, Huck, O, Amar, S. Kava-241 reduced periodontal destruction in a collagen antibody primed Porphyromonas gingivalis model of periodontitis. J Clin Periodontol. 2017 Nov; 44(11): 1123–1132. https://doi.org/10.1111/jcpe.12784. Epub 2017 Sep 21. PMID: 28746780; PMCID: PMC5650496. Concerns were raised by a third party regarding the appearance of Figure
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Single‐cell analysis reveals a unique microenvironment in peri‐implantitis J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-03 J. Li, L. J. Ye, Y. W. Dai, H. W. Wang, J. Gao, Y. H. Shen, F. Wang, Q. G. Dai, Y. Q. Wu
AimThis study aimed to reveal the unique microenvironment of peri‐implantitis through single‐cell analysis.Materials and MethodsHerein, we performed single‐cell RNA sequencing (scRNA‐seq) of biopsies from patients with peri‐implantitis (PI) and compared the results with healthy individuals (H) and patients with periodontitis (PD).ResultsDecreased numbers of stromal cells and increased immune cells
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Influence of scanning protocol on the accuracy of complete‐arch digital implant scans: An in vitro study Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-03 Adam Hamilton, William Matthew Negreiros, Shruti Jain, Matthew Finkelman, German O. Gallucci
ObjectiveThis in‐vitro study assessed the influence of two intraoral scanning (IOS) protocols on the accuracy (trueness and precision) of digital scans performed in edentulous arches.MethodsTwenty‐two abutment‐level master casts of edentulous arches with at least four implants were scanned repeatedly five times, each with two different scanning protocols. Protocol A (IOS‐A) consisted of scanning the
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A randomized clinical trial on zirconia versus titanium implants in maxillary single tooth replacement Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-03 J. H. W. de Beus, M. S. Cune, J. W. A. Slot, C. Jensen‐Louwerse, S. la Bastide‐van Gemert, H. J. A. Meijer, G. M. Raghoebar, U. Schepke
ObjectivesThis RCT aimed to compare zirconia and titanium dental implants in the maxillary premolar region. The comparison was based on marginal bone level (MBL) changes, clinical parameters, aesthetic outcomes, and patient related outcome measures (PROMs) 1 year after prosthetic loading.Materials and MethodsFifty patients were randomly assigned to receive either a zirconia (ZrO2, n = 25) implant or
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Echo‐intensity characterization at implant sites and novel diagnostic ultrasonographic markers for peri‐implantitis J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-04-02 Maria Elisa Galarraga‐Vinueza, Shayan Barootchi, Leonardo Mancini, Hamoun Sabri, Frank Schwarz, German O. Gallucci, Lorenzo Tavelli
AimTo apply high‐frequency ultrasound (HFUS) echo intensity for characterizing peri‐implant tissues at healthy and diseased sites and to investigate the possible ultrasonographic markers of health versus disease.Materials and MethodsSixty patients presenting 60 implants diagnosed as healthy (N = 30) and peri‐implantitis (N = 30) were assessed with HFUS. HFUS scans were imported into a software where
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Maxillary sinus floor augmentation with autogenous bone graft compared with composite grafts: A one‐year single‐blinded randomized controlled trial Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-02 Thomas Starch‐Jensen, Marianne Ahmad, Niels Henrik Bruun, Jonas Peter Becktor
ObjectiveThe objective was to assess the one year implant treatment outcome and patient‐related outcome measures (PROMs) following maxillary sinus floor augmentation (MSFA) with autogenous bone graft (ABG) from the zygomatic buttress (control) compared with 1:1 mixture of ABG and anorganic porcine bone mineral (APBM) (Test I) or biphasic bone graft material (BBGM) (Test II).Materials and MethodsSixty
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Association of periodontitis with gastrointestinal tract disorders: A bidirectional Mendelian randomization study J. Periodontol. (IF 4.3) Pub Date : 2024-04-02 Yuqiang Wang, Jiakang Zhu, Ying Tang, Cui Huang
BackgroundThe bidirectional link of periodontitis (PD) and gastrointestinal tract (GIT) disorders has been investigated in previous epidemiological studies; however, the conclusions still remain controversial. The aim of this study was to comprehensively explore the bidirectional causal effect between PD and various GIT diseases.MethodsBased on summary‐level data of genome‐wide association studies
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Evaluation of acceptance and preference of topical lidocaine application versus articaine injection anesthesia after nonsurgical periodontal treatment: A randomized clinical trial J. Periodontol. (IF 4.3) Pub Date : 2024-04-02 Christof Dörfer, Kathrin Chmiela, Nicole B. Arweiler, Gregor J. Petersilka, Henrik Dommisch, Ralph Heckel, Maren Kahl, Denica Kuzmanova, Peter Purucker, Claudia Springer
BackgroundTo compare acceptance and preference of topical lidocaine gel anesthesia with articaine injection anesthesia in patients with moderate periodontitis undergoing scaling and root debridement.MethodsNinety‐one patients completed this randomized multicenter split‐mouth controlled study and underwent two separate periodontal treatment sessions on different days, one with a topical intrapocket
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Immediate versus early implant placement for single tooth replacement in the aesthetic area: A systematic review and meta‐analysis Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-04-01 Axelle Ickroth, Lorenz Seyssens, Véronique Christiaens, Jeremy Pitman, Jan Cosyn
ObjectivesTo compare immediate implant placement (IIP) with early implant placement (EIP) for single tooth replacement in the aesthetic area in terms of aesthetic, clinical, and patient‐reported outcomes.Materials and MethodsTwo independent reviewers conducted an electronic literature search in PubMed, Web of Science, Embase, and Cochrane databases as well as a manual search to identify eligible clinical
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High-Performance Dental Resins Containing a Starburst Monomer J. Dent. Res. (IF 7.6) Pub Date : 2024-03-29 S.Q. Dai, W. Zhou, L.Y. Duan, K. Tang, Z.Y. Yang, R.J. Cao, F.R. Tay, L.N. Niu, J.H. Chen
Dimethacrylate-based chemistries feature extensively as resin monomers in dental resin–based materials due to their distinguished overall performance. However, challenges endure, encompassing inadequate mechanical attributes, volumetric shrinkage, and estrogenicity. Herein, we first synthesized a novel resin monomer, 9-armed starburst polyurethane acrylate (NPUA), via the grafting-onto approach. Compared
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FUT8-mediated aberrant N-glycosylation of SEMA7A promotes head and neck squamous cell carcinoma progression Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-03-28 Zhonglong Liu, Xiaoyan Meng, Yuxin Zhang, Jingjing Sun, Xiao Tang, Zhiyuan Zhang, Liu Liu, Yue He
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Periodontitis exacerbates pulmonary hypertension by promoting IFNγ+ T cell infiltration in mice Int. J. Oral Sci. (IF 14.9) Pub Date : 2024-03-28 Xiaoqian Meng, Linjuan Du, Shuo Xu, Lujun Zhou, Boyan Chen, Yulin Li, Chumao Chen, Huilin Ye, Jun Zhang, Guocai Tian, Xuebing Bai, Ting Dong, Wenzhen Lin, Mengjun Sun, Kecong Zhou, Yan Liu, Wuchang Zhang, Shengzhong Duan
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Understanding exososmes: Part 3—therapeutic + diagnostic potential in dentistry Periodontol. 2000 (IF 18.6) Pub Date : 2024-03-28 Richard J. Miron, Nathan E. Estrin, Anton Sculean, Yufeng Zhang
Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells with the ability to communicate with other tissues and cell types over long distances. Their use in regenerative medicine has gained tremendous momentum recently due to their ability to be utilized as therapeutic options for a wide array of various diseases. Over 5000 publications are currently being published
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Accuracy of cone‐beam computed tomography in imaging the components of the periodontal phenotype Periodontol. 2000 (IF 18.6) Pub Date : 2024-03-28 Ralf Schulze, Emilio Couso‐Queiruga, Christos Katsaros
The components and dimensions of the periodontal and peri‐implant phenotype have a high relevance in contemporary dental research and should be taken into consideration in the decision‐making process in the management of a variety of clinical scenarios to optimize the outcomes of therapy. Various assessment methods for quantifying and classifying the phenotypical dimensions have emerged and developed
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Heterogeneous Association of Tooth Loss with Functional Limitations J. Dent. Res. (IF 7.6) Pub Date : 2024-03-27 Y. Matsuyama, J. Aida, K. Kondo, K. Shiba
Tooth loss is prevalent in older adults and associated with functional capacity decline. Studies on the susceptibility of some individuals to the effects of tooth loss are lacking. This study aimed to investigate the heterogeneity of the association between tooth loss and higher-level functional capacity in older Japanese individuals employing a machine learning approach. This is a prospective cohort
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Association between dietary patterns and periodontal disease: The OsteoPerio cohort study J. Clin. Periodontol. (IF 6.7) Pub Date : 2024-03-27 Yihua Yue, Kathleen M. Hovey, Michael J. LaMonte, Jean Wactawski-Wende, Chris A. Andrews, Amy E. Millen
To examine the association of dietary patterns with periodontal disease (PD) and its progression over 5 years.
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Supportive therapy following peri‐implantitis treatment: A retrospective study on compliance Clin. Oral. Implants Res. (IF 4.3) Pub Date : 2024-03-26 Alberto Monje, Pablo Galindo‐Fernández, José Nart
BackgroundThe compliance rate with supportive therapy following peri‐implantitis treatment (SPIT) remains unknown. The present retrospective study was carried out to assess the compliance rate and the factors influencing compliance in a private practice setting.Materials and MethodsPatients were divided into three groups according to compliance rate: regular compliance (RC ≥2 SPIT/year), erratic compliance