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Obstetric Complications and Birth Outcomes After Antenatal Coronavirus Disease 2019 (COVID-19) Vaccination. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-17 Kimberly K Vesco, Anna E Denoble, Heather S Lipkind, Elyse O Kharbanda, Malini B DeSilva, Matthew F Daley, Darios Getahun, Ousseny Zerbo, Allison L Naleway, Lisa Jackson, Joshua T B Williams, Thomas G Boyce, Candace C Fuller, Eric S Weintraub, Gabriela Vazquez-Benitez
To evaluate the association between antenatal messenger RNA (mRNA) coronavirus disease 2019 (COVID-19) vaccination and risk of adverse pregnancy outcomes.
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Syphilis Treatment Among People Who Are Pregnant in Six U.S. States, 2018-2021. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-17 Ayzsa Tannis, Kathryn Miele, Jeffrey M Carlson, Kevin P O'Callaghan, Kate R Woodworth, Breanne Anderson, Aisha Praag, Kourtney Pulliam, Nicole Coppola, Teri' Willabus, Deborah Mbotha, Dejene Abetew, Salvatore Currenti, Nicole D Longcore, Amanda Akosa, Dana Meaney-Delman, Van T Tong, Suzanne M Gilboa, Emily O Olsen
To describe syphilis treatment status and prenatal care among people with syphilis during pregnancy to identify missed opportunities for preventing congenital syphilis.
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Drug-Induced Liver Injury in Pregnancy: The U.S. Drug-Induced Liver Injury Network Experience. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-16 Umair Masood, Nicholas Venturini, Paola Nicoletti, Andrew Dellinger, David Kleiner, Herbert L Bonkovsky, Huiman Barnhart, Raj Vuppalanchi, Simona Rossi, Joseph A Odin, Tatyana Kushner
There are limited data on the causative agents and characteristics of drug-induced liver injury in pregnant individuals. Data from patients with drug-induced liver injury enrolled in the ongoing multicenter Drug-Induced Liver Injury Network between 2004 and 2022 and occurring during pregnancy or 6 months postpartum were reviewed and compared with cases of drug-induced liver injury in nonpregnant women
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Neurologic Emergencies in Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-16 Shaun R Wesley, G Edward Vates, Loralei L Thornburg
Neurologic emergencies in pregnancy require prompt evaluation and early, focused intervention to improve neurologic outcomes for the affected person and to avoid further injury. Neurologic events in pregnancy, although rare, present a time of extreme risk of permanent injury for the person who is pregnant. Therefore, obstetric clinicians should be well versed in the risk factors for potential neurologic
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National Postpartum Permanent Contraception Practices and Perceived Barriers. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-16 Ellen Murphy, Andrea Pelletier, Kathryn Fay, Deborah Bartz
Single institution-level studies have demonstrated low postpartum permanent contraception fulfillment rates after vaginal birth. To explore the national scope of the problem, we collected cross-sectional survey data from faculty at 109 U.S. academic medical centers to elicit perceptions about postpartum permanent contraception practices after vaginal birth, including barriers to and changes in practice
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Pathophysiology and Clinical Implications of Ovarian Endometriomas. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-16 Farr R Nezhat, Ann M Cathcart, Ceana H Nezhat, Camran R Nezhat
Ovarian endometriomas affect many patients with endometriosis and have significant effects on quality of life, fertility, and risk of malignancy. Endometriomas range from small (1-3 cm), densely fibrotic cysts to large (20 cm or greater) cysts with varying degrees of fibrosis. Endometriomas are hypothesized to form from endometriotic invasion or metaplasia of functional cysts or alternatively from
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Trends in Reporting of Nuchal Translucency Measurements After the Clinical Introduction of Cell-Free DNA Screening. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-11 Timothy Wen, Loralei L Thornburg, Mary E Norton, Lawrence D Platt, Lorraine Dugoff, Ashley Hesson, Jean L Spitz, Gregory Toland, Bryann Bromley
Nuchal translucency (NT) measurement in conjunction with serum analytes has been used for first-trimester aneuploidy screening in the United States since 2005. We sought to analyze the trends in reporting of NT measurements to the Nuchal Translucency Quality Review program in all pregnancies beginning after the clinical introduction of cell-free DNA (cfDNA) screening for fetal aneuploidy in 2011. Overall
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Premature Ovarian Insufficiency After Coronavirus Disease 2019 (COVID-19): Autoimmune Follicle-Stimulating Hormone (FSH) and FSH Receptor Blockade. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-05 Rachel Stern, Moses Bibi, Martin D Keltz
Since the onset of the coronavirus disease (COVID-19) pandemic, a variety of long-COVID-19 symptoms and autoimmune complications have been recognized.
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Adverse Pregnancy Outcomes and Predicted 30-Year Risk of Maternal Cardiovascular Disease 2-7 Years After Delivery. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-05 Kartik K Venkatesh, Sadiya S Khan, Lynn M Yee, Jiqiang Wu, Rebecca McNeil, Philip Greenland, Judith H Chung, Lisa D Levine, Hyagriv N Simhan, Janet Catov, Christina Scifres, Uma M Reddy, Victoria L Pemberton, George Saade, C Noel Bairey Merz, William A Grobman
To determine whether adverse pregnancy outcomes are associated with a higher predicted 30-year risk of atherosclerotic cardiovascular disease (CVD; ie, coronary artery disease or stroke).
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Patient Location and Disparities in Access to Fertility Preservation for Women With Gynecologic or Breast Cancer. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-05 Alexa Kanbergs, Kirsten Jorgensen, Nuria Agusti, David Viveros-Carreño, Chi-Fang Wu, Roni Nitecki, John A Harris, Terri Woodard, Ryan Ramphul, Jose Alejandro Rauh-Hain
To assess the effect of geographic factors on fertility-sparing treatment or assisted reproductive technology (ART) utilization among women with gynecologic or breast cancers.
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Association Between Hypertensive Disorders of Pregnancy and Interval Neurocognitive Decline: An Analysis of the Hispanic Community Health Study/Study of Latinos. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-05 Tali Elfassy, Shathiyah Kulandavelu, Leah Dodds, Robert A Mesa, Tatjana Rundek, Vera Sharashidze, Michael Paidas, Martha L Daviglus, Michelle A Kominiarek, Ariana M Stickel, Krista M Perreira, Marissa A Kobayashi, Tanya P Garcia, Carmen R Isasi, Richard B Lipton, Hector M González
To evaluate whether hypertensive disorders of pregnancy, including gestational hypertension, preeclampsia, and eclampsia, are associated with cognitive decline later in life among U.S. Hispanic/Latina individuals.
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High-Dose Buprenorphine Initiation in the Management of Opioid Use Disorder in Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-04 Marissa Berry, Miranda K Kiefer, Katherine A Hinely, Heather Bowden, Audra Jordan, Michael Vilensky, Kara M Rood
Buprenorphine is commonly used as a treatment for opioid use disorder (OUD). Transition to buprenorphine traditionally has been done using a low-dose initiation regimen due to concerns surrounding precipitated withdrawal. There are increasing data supporting use of a high-dose initiation regimen in the nonpregnant population. This retrospective case series describes six individuals with OUD who underwent
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Biomarker Prediction of Preeclampsia With Severe Features. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-04-03
This Clinical Practice Update provides guidance for the use of a biomarker immunoassay to aid in the risk assessment of certain pregnant women hospitalized for hypertensive disorders for the progression to preeclampsia with severe features. This document updates Practice Bulletin No. 222, Gestational Hypertension and Preeclampsia(Obstet Gynecol 2020;135:e237-60).
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Diagnosis and Management of Cervical Squamous Intraepithelial Lesions in Pregnancy and Postpartum. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-29 Alyssa Larish, Margaret E Long
Perinatal care provides important health care opportunities for many individuals at risk for cervical cancer. Pregnancy does not alter cervical cancer screening regimens. ASCCP risk-based management has a colposcopy threshold of a 4% immediate risk of cervical intraepithelial neoplasia (CIN) 3 or cancer, but the actual risk can be considerably higher based on current and past screening results. Improving
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Long-Term Risk of Reintervention After Surgical Leiomyoma Treatment in an Integrated Health Care System. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-28 Susanna D Mitro, Fei Xu, Catherine Lee, Eve Zaritsky, L Elaine Waetjen, Lauren A Wise, Monique M Hedderson
To compare long-term risk of reintervention across four uterus-preserving surgical treatments for leiomyomas and to assess effect modification by sociodemographic factors in a prospective cohort study in an integrated health care delivery system.
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Active Compared With Passive Voiding Trials After Midurethral Sling Surgery: A Systematic Review. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-28 Siri Drangsholt, Cassidy Lleras, Rebecca Kindler, Maytal Babajanian, Bracha Pollack, Aleksandr Harutyunyan, Matan Grunfeld, Yehuda Gejerman, Katherine Kilkenny, Moshe Bulmash, Rahim Hirani, Parissa Alerasool, Christopher McNeil, Patrick Popiel, Elizabeth D Drugge, Cara Grimes
To compare active with passive voiding trials on the rate of passing a trial of void and discharge rates with catheter in women who have undergone midurethral sling for treatment of stress urinary incontinence (SUI).
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Equitable Artificial Intelligence in Obstetrics, Maternal-Fetal Medicine, and Neonatology. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-28 Ryan M McAdams, Tiffany L Green
Artificial intelligence (AI) offers potential benefits in the interconnected fields of obstetrics, maternal-fetal medicine, and neonatology to bridge disciplinary silos for a unified approach. Artificial intelligence has the capacity to improve diagnostic accuracy and clinical decision making for the birthing parent-neonate dyad. There is an inherent risk of ingrained biases in AI that perpetuate existing
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Obstetric Racial Disparities in the Era of the ARRIVE (A Randomized Trial of Induction Versus Expectant Management) Trial and the Coronavirus Disease 2019 (COVID-19) Pandemic. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-28 Sarahn M Wheeler, Tracy Truong, Shakthi Unnithan, Hwanhee Hong, Evan Myers, Geeta K Swamy
To evaluate the influence of the ARRIVE (A Randomized Trial of Induction Versus Expectant Management) trial and the coronavirus disease 2019 (COVID-19) pandemic on racial and ethnic differences in labor induction, pregnancy-associated hypertension, and cesarean delivery among non-Hispanic Black and non-Hispanic White low-risk, first-time pregnancies.
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Association Between Intrapartum Nitrous Oxide for Labor Analgesia and Short-Term Neonatal Outcomes. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-14 Anabel Starosta, Lisbet Lundsberg, Jennifer Culhane, Caitlin Partridge, Olga Grechukhina, Moeun Son
To evaluate the association between intrapartum nitrous oxide use and adverse short-term neonatal outcomes.
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A Contemporary View of Menopausal Hormone Therapy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-14 Barbara Levy, James A Simon
Enthusiasm for the use of hormones to ameliorate symptoms of perimenopause and menopause has waxed and waned over the years. Both treatment for symptoms and training of women's health care practitioners in the management of menopause have sharply declined since publication of the Women's Health Initiative initial results in 2002. Findings from that trial, which treated a population of older, asymptomatic
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Child Protection System Removal and Short-Interval Births Among Individuals With Prenatal Substance Use. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-14 Julia Reddy, Davida Schiff, Mishka Terplan, Hendree Jones, Emily Putnam-Hornstein
Child protection systems often intervene after substance-exposed births but are not designed to address the postpartum needs of the delivering parent. In this retrospective cohort study, we aimed to estimate the association between early child protection system removal and high-risk subsequent birth trajectories among a cohort of mothers with substance-exposed births in California. Of 6,893 births
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Pregnancy Outcomes After Laparoscopic Radiofrequency Ablation of Uterine Leiomyomas Compared With Myomectomy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-03-01 Antoinette Allen, Michael Schembri, Ram Parvataneni, L Elaine Waetjen, Shira Varon, Naghmeh Salamat-Saberi, Shawn Tassone, Nicole Williams, Kimberly A Kho, Vanessa L Jacoby
To compare pregnancy outcomes after laparoscopic radiofrequency ablation and myomectomy.
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An Update on Prenatal Diethylstilbestrol Exposure and High-Grade Squamous Intraepithelial Lesions of the Lower Genital Tract. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-29 Rebecca Troisi, Kimberly Bertrand, Elizabeth E Hatch, William C Strohsnitter, Kjersti Aagaard, Stanley J Robboy, Gretchen Gierach, Linda Titus
Women with prenatal diethylstilbestrol exposure are excluded from less frequent cervical cancer screening because of their increased neoplasia risk. We report the results of a prospective follow-up study of prenatal diethylstilbestrol exposure and lower genital tract high-grade (grade 2 or higher) squamous intraepithelial lesions (HSIL). The age-adjusted risk of HSIL among diethylstilbestrol-exposed
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Association of Adverse Childhood Experiences and Resilience With Depression and Anxiety During Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-29 Carey R Watson, Abigail Eaton, Cynthia I Campbell, Stacey E Alexeeff, Lyndsay A Avalos, Kathryn K Ridout, Kelly C Young-Wolff
This was a retrospective cohort study of pregnant individuals in the Kaiser Permanente Northern California system who were screened for adverse childhood experiences and resilience as part of standard prenatal care at about 16 weeks of gestation. Overall, 14,625 pregnancies were included; 17.0% had newly identified depression; 9.8% had newly identified depression symptoms; and 8.9% had newly identified
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Universal Fetal Echocardiography for Pregestational Diabetes Mellitus: A Cost-Effectiveness Analysis. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-29 Leah M Savitsky, Caitlin Hamilton, Mary Sterrett, Kelsey Olerich, Kimberly Ma, Catherine M Albright
To evaluate the cost effectiveness of universal fetal echocardiogram for patients with pregestational diabetes mellitus by first-trimester hemoglobin A1c (Hb A1c) level.
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Applying Tension to the Transcervical Foley Balloon and Delivery Times in Term Nulliparous Women Undergoing Induction of Labor: A Randomized Controlled Trial. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-29 Meagan Benson, Lena Younes, Alisha Watson, George R Saade, Antonio F Saad
To investigate the effects of applying tension to a transcervical Foley balloon on delivery time in term nulliparous patients undergoing labor induction.
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Timing of Coronavirus Disease 2019 (COVID-19) Vaccination and Effects on Menstrual Cycle Changes. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-27 Alison Edelman, Emily R Boniface, Victoria Male, Sharon Cameron, Eleonora Benhar, Leo Han, Kristen A Matteson, Agathe van Lamsweerde, Jack T Pearson, Blair G Darney
To assess whether menstrual cycle timing (follicular or luteal phase) of coronavirus disease 2019 (COVID-19) vaccine administration is associated with cycle length changes.
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Treating Mild Chronic Hypertension During Pregnancy: A Cost-Effectiveness Analysis. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-22 Uma Doshi, Sarina Chaiken, Alyssa Hersh, Karen J Gibbins, Aaron B Caughey
To assess the cost effectiveness of targeting a blood pressure of less than 140/90 mm Hg compared with 160/105 mm Hg.
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Hospital Discharge Codes and Overestimating Severe Maternal Morbidity During Delivery Hospitalization. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-22 Johanna Quist-Nelson, Marie-Louise Meng, Divya Mallampati, Jerome J Federspiel, Lauren M Kucirka, Matthew Fuller, M Kathryn Menard
Our objective was to identify birth hospitalization severe maternal morbidity (SMM) diagnoses that were also coded during prior encounters and, thus, potentially falsely carried forward as de novo SMM events. This retrospective cohort study included pregnant patients with births between 2016 and 2020. We applied the SMM algorithm to the birth hospitalization and encounters occurring prepregnancy, antepartum
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A Treatment Algorithm for High-Tone Pelvic Floor Dysfunction. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-22 Michele Torosis, Erin Carey, Kristin Christensen, Melissa R Kaufman, Kimberly Kenton, Rhonda Kotarinos, H Henry Lai, Una Lee, Jerry L Lowder, Melanie Meister, Theresa Spitznagle, Kelly Wright, A Lenore Ackerman
To develop evidence- and consensus-based clinical practice guidelines for management of high-tone pelvic floor dysfunction (HTPFD). HTPFD is a neuromuscular disorder of the pelvic floor characterized by non-relaxing pelvic floor muscles, resulting in lower urinary tract and defecatory symptoms, sexual dysfunction, and pelvic pain. Despite affecting 80% of women with chronic pelvic pain, there are no
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Uterine Sacculation With Entrapped Placenta After Delivery. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-13 Michael T Solotke, Glenn Boyles, Kara Rood, Emily Hinchcliff, Jeanne M Horowitz, Lynn M Yee
Uterine sacculation refers to a temporary pouch or sac within the uterus that may contain the placenta or fetal parts and that may be diagnosed antepartum or after delivery. There is very limited published information about this rare condition and its management.
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Angiogenic Biomarkers in Preeclampsia. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-13 Richard M Burwick, M Hellen Rodriguez
Preeclampsia contributes disproportionately to maternal and neonatal morbidity and mortality throughout the world. A critical driver of preeclampsia is angiogenic imbalance, which is often present weeks to months before overt disease. Two placenta-derived angiogenic biomarkers, soluble fms-like tyrosine kinase 1 (sFlt-1) and placental growth factor (PlGF), have proved useful as diagnostic and prognostic
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A Comparison of Newer and Traditional Approaches to Diagnosing Vaginal Infections. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-13 Anna Powell, Oluwatosin Goje, Paul Nyirjesy
Molecular diagnostic testing (eg, polymerase chain reaction [PCR]-based vaginitis testing) is widely used in clinical practice, although vaginitis experts have reservations about its use for vaginitis diagnosis. As with any new technology, cost to the health system is a large concern. Although clinical evaluation of signs and symptoms along with wet mount microscopy is traditionally used for vaginitis
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Effects of Obesity on Urogynecologic Prolapse Surgery Outcomes: A Systematic Review and Meta-analysis. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-08 Nancy E Ringel, Stacy M Lenger, Rachel High, Alexandriah Alas, Sara Houlihan, Olivia H Chang, Jon Pennycuff, Ruchira Singh, Amanda White, Lioudmila Lipitskaia, Sadikah Behbehani, David Sheyn, Bela Kudish, Mikio Nihira, Ambereen Sleemi, Cara Grimes, Ankita Gupta, Ethan M Balk, Danielle D Antosh
To systematically review the literature on outcomes of pelvic organ prolapse (POP) surgery in patients from various body mass index (BMI) categories to determine the association between obesity and surgical outcomes.
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Endometrial Cancer in a Transgender Man with Prolonged Exogenous Testosterone Use. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-08 Stephanie Gill, Michelle Anderson, Joannie Neveu
Hormone therapy (HT) in transgender males requires monitoring. For amenorrheic transmasculine individuals on HT, episodes of abnormal vaginal bleeding should be assessed promptly.
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Understanding New Recommendations for Respiratory Syncytial Virus Prevention in Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-08 Rebecca Horgan, Brenna L Hughes, Jerri Waller, Yara Hage Diab, George Saade
Respiratory syncytial virus (RSV) is a significant cause of infant morbidity and mortality worldwide with peak hospitalization rates for RSV-mediated illnesses between 2 and 3 months of life. Until very recently, prevention strategies for RSV involved primarily passive immunization of neonates at high risk with monoclonal antibodies and promotion of breastfeeding. The Centers for Disease Control and
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Neonatal Birth Weight With Daily Compared With Every-Other-Day Glucose Monitoring in Gestational Diabetes Mellitus: A Randomized Controlled Trial. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-08 Kristina Martimucci Feldman, Arielle Coughlin, Jasmin Feliciano, Guillaume Stoffels, Kelly Z Wang, Tirtza Spiegel Strauss, Olivia Grubman, Zainab Al-Ibraheemi, David Cole, Graham Ashmead, Farrah Hussain, Sophia Scarpelli Shchur, Deborah Lee, Lois Brustman
To assess whether universal use of every-other-day glucose monitoring in patients with gestational diabetes mellitus (GDM) resulted in similar birth weights and medication use and was preferred by the patient compared with traditional daily glucose monitoring.
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Late Preterm Antenatal Steroids for Reduction of Neonatal Respiratory Complications: A Randomized Controlled Trial. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-08 Hilda Yenuberi, Benjamin Ross, Richa Sasmita Tirkey, Santosh Joseph Benjamin, Swati Rathore, Reka Karuppusami, Aadarsh Lal, Niranjan Thomas, Jiji Elizabeth Mathew
To evaluate the efficacy of antenatal corticosteroids in reducing neonatal respiratory complications when administered to those at risk of preterm delivery between 34 and 36 6/7 weeks of gestation.
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Structural Racism and Use of Labor Neuraxial Analgesia Among Non-Hispanic Black Birthing People. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-01 Jean Guglielminotti, Allison Lee, Ruth Landau, Goleen Samari, Guohua Li
To assess the association between structural racism and labor neuraxial analgesia use.
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Enabling Technologies for Gynecologic Vaginal Surgery: A Systematic Review. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-01 Sunil Balgobin, Ethan M Balk, Anne E Porter, Meenal Misal, Tamara Grisales, Kate V Meriwether, Peter C Jeppson, Paula J Doyle, Sarit O Aschkenazi, Jeannine M Miranne, Deslyn T Hobson, David L Howard, Saifuddin Mama, Ankita Gupta, Danielle D Antosh
To systematically review the literature to evaluate clinical and surgical outcomes for technologies that facilitate vaginal surgical procedures.
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Association Between Neighborhood Deprivation in Early Pregnancy and Gestational Diabetes Mellitus. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-01 Emily F Liu, Assiamira Ferrara, Sneha B Sridhar, Mara B Greenberg, Monique M Hedderson
To evaluate whether having a pregnancy in a deprived neighborhood was associated with an increased risk of gestational diabetes mellitus (GDM) compared with having a pregnancy in the least-deprived neighborhoods.
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Inpatient Management of Hyperemesis Gravidarum. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-01 Shannon M Clark, Xue Zhang, Daphne Arena Goncharov
Hyperemesis gravidarum has a reported incidence of approximately 0.3-3% of pregnancies. Without treatment, refractory hyperemesis gravidarum can result in dehydration, electrolyte deficiencies, and severe nutritional deficiencies, resulting in significant maternal morbidity. The overall goals of inpatient management of refractory hyperemesis gravidarum are the resumption of oral intake to an adequate
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Addressing Privacy Concerns Surrounding Oocyte Donation in the United States: Gone With Anonymity. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-02-01 Shelun Tsai, Jennifer L Eaton
Oocyte donation has greatly expanded in the past several decades since the first procedure was performed in 1983. According to the Centers for Disease Control, the number of cycles using donor oocytes increased from 18,011 cycles in 2010 to 27,131 cycles in 2019. Oocyte donation has become an important reproductive option for women with diminished ovarian reserve, recurrent failed in vitro fertilization
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Outcomes After Induction of Labor Compared With Dilation and Evacuation for the Management of Rupture of Membranes in the Second Trimester. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-23 Elizabeth A Hoffman, Jason Kaufman, Nathanael C Koelper, Sarita Sonalkar, Andrea H Roe
Previable and periviable rupture of membranes is associated with significant morbidity for the pregnant patient. For those who have a choice of options and undergo active management, it is not known how the risks of induction of labor compare with those for dilation and evacuation (D&E). We performed a retrospective cohort study of patients with rupture of membranes between 14 0/7 and 23 6/7 weeks
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Neurodevelopment of Children Whose Mothers Were Randomized to Low-Dose Aspirin During Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-23 Matthew K Hoffman, Shivaprasad Goudar, Sangappa Dhaded, Lester Figueroa, Manolo Mazariegos, Nancy F Krebs, Jamie Westcott, Shiyam Sunder Tikmani, Fatima Karim, Sarah Saleem, Robert L Goldenberg, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Archana Patel, Prabir Das, Patricia Hibberd, Elwyn Chomba, Musaku Mwenchanya, Waldemar A Carlo, Marissa Trotta, Alexis Williams, Janet Moore, Tracy Nolen
Because low-dose aspirin is now commonly prescribed in pregnancy, we sought to assess the association between early antenatal exposure and child neurodevelopment.
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Permanent Contraception: Ethical Issues and Considerations: ACOG Committee Statement No. 8. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-1-18
Permanent contraception is the most used method of contraception among women aged 15-49 years and is one of the most straightforward surgical procedures an obstetrician-gynecologist can perform. At the same time, this therapeutic option is enormously complex when considered from a historical, sociological, or ethical perspective. This Committee Statement reviews ethical issues related to permanent
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The Evaluation of Payment for Obstetric and Gynecology Services: From ACOG. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-1-18
To perform an environmental scan of the current status of reimbursement for obstetric and gynecology services and identify problematic issues and opportunities for change. The areas that were evaluated include the American Medical Association (AMA) relative value unit assignment process, payer rates (where available), and trends in employment and salary determination for obstetrician-gynecologists
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Immunosuppressant Medications in Pregnancy. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-16 Antonio F Saad, Luis D Pacheco, George R Saade
Pregnant patients are often on immunosuppressant medications, most commonly to manage transplantation or autoimmune disorders. Most immunosuppressant agents, including tacrolimus, corticosteroids, azathioprine, and calcineurin inhibitors, are safe during pregnancy and lactation. However, mycophenolic acid is associated with higher risks of birth defects and should be avoided in pregnancy. Tacrolimus
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Efficacy and Safety of Fezolinetant for the Treatment of Menopause-Associated Vasomotor Symptoms: A Meta-analysis. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-16 Krishna Nikhila Bonga, Archana Mishra, Rituparna Maiti, Biswa Mohan Padhy, Bikash Ranjan Meher, Anand Srinivasan
To evaluate the efficacy and adverse events of fezolinetant for treating vasomotor symptoms (VMS) of menopause.
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Venous Thromboembolic Risk of Estradiol Valerate-Dienogest Compared with Ethinyl Estradiol-Levonorgestrel Combined Oral Contraceptives. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-16 Anja Bauerfeind, Sophia von Stockum, Tanja Boehnke, Klaas Heinemann
This pooled analysis compared the risk of venous thromboembolism (VTE) associated with combined oral contraceptives (COCs) containing estradiol (E2) valerate-dienogest with those containing ethinyl E2-levonorgestrel. Data were retrieved from two large, prospective, observational cohort studies. Propensity score subclassification was applied to balance baseline parameters between the COC user cohorts
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Naltrexone Compared With Buprenorphine or Methadone in Pregnancy: A Systematic Review. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-16 Sreevalli Atluru, Alyssa K Bruehlman, Porcia Vaughn, Charles W Schauberger, Marcela C Smid
Although naltrexone is an evidence-based medication for opioid use disorder (MOUD), few data are available with use in pregnancy. Our objective was to assess outcomes of pregnant individuals with opioid use disorder (OUD) taking naltrexone compared with those taking methadone or buprenorphine.
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Longitudinal Reoperation Risk After Apical Prolapse Procedures in Women Aged 65 Years and Older. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-16 Alexander A Berger, Carol E Bretschneider, W Thomas Gregory, Vivian Sung
To describe longitudinal reoperation risk among older women undergoing surgery for apical pelvic organ prolapse (POP) and to compare risk of reoperation for prolapse and complications among different surgical approaches.
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Activity Restrictions After Gynecologic Surgery. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Margaret G Mueller, Kimberly Kenton
Gynecologic surgeons have traditionally restricted the physical activity of postoperative patients. Minimally invasive surgery and enhanced recovery after surgery programs have contributed to decreased hospital stays and more expeditious recovery. In this narrative review, we review the current state of postoperative activity restrictions in gynecology and other specialties, the purported risks and
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Urethral Bulking With Polyacrylamide Hydrogel Compared With Other Treatments for Stress Urinary Incontinence: A Cost-Effectiveness Analysis. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Olivia H Chang, Jonathan P Shepherd, Lauren A Cadish, Shannon L Wallace, Brad St Martin, Eric R Sokol
Our objective was to perform a cost-effectiveness analysis comparing polyacrylamide hydrogel urethral bulking with other surgical and nonsurgical treatments for stress urinary incontinence (SUI). We created a cost-effectiveness analysis using TreeAge Pro, modeling eight SUI treatments. Treatment with midurethral sling (MUS) had the highest effectiveness (1.86 quality-adjusted life-years [QALYs]), followed
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Geographic Access to Early Pregnancy Loss Management. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Jamie W Krashin, Patricia Black, Eric Brannen, Charlotte C Gard, Yan Lin, Margaret Greenwood-Ericksen, Victoria Y Trujillo, Gillian Burkhardt, Courtney A Schreiber
Early pregnancy loss (EPL) is common, but patients face barriers to the most effective medication (mifepristone followed by misoprostol) and procedural (uterine aspiration) management options. This cross-sectional geospatial analysis evaluated access in New Mexico to mifepristone and misoprostol and uterine aspiration in emergency departments (comprehensive) and to uterine aspiration anywhere in a
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Sexual Health in Women Affected by Gynecologic or Breast Cancer. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Katina Robison, Amita Kulkarni, Don S Dizon
Sexual health problems are prevalent among women affected by gynecologic or breast cancer. It is important to understand the effects cancer treatment can have on sexual health and to have the tools necessary to identify and treat sexual health problems. This Clinical Expert Series discusses practical methods for routinely screening for sexual dysfunction and reviews sexual health treatment options
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Association Between Length of Maternity Leave and Breastfeeding Duration in the United States: A Systematic Review. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Lorena Wicklund, Allison Epstein, Heidi Szugye, Mary Schleicher, Suet Kam Lam
To perform a systematic review to assess the association between the length of maternity leave and breastfeeding duration in the United States.
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Effect of Uterine Leiomyomas on Noninvasive Prenatal Testing Parameters in the First Trimester. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-11 Teodora R Kolarova, Ali Alderson, Hayley MacKinnon, Leah Chen, Jillian G Buchan, Christina Lockwood, Raj Shree
Uterine leiomyomas may affect the performance of cell-free DNA (cfDNA)-based noninvasive prenatal testing (NIPT). We conducted a retrospective cohort study of pregnant individuals with and without leiomyomas undergoing first-trimester cfDNA-based NIPT. Characteristics of NIPT in patients with leiomyomas (n=122) were compared with those in patients without leiomyomas (n=937). Mean fetal fraction was
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Evaluation of Recurrent Pregnancy Loss. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-04 Viviana de Assis, Claudio Schenone Giugni, Stephanie T Ros
Recurrent pregnancy loss (RPL) affects approximately 5% of couples. Although RPL definitions vary across professional societies, an evaluation after a second clinically recognized first-trimester pregnancy loss is recommended. Good quality evidence links parental chromosomal rearrangements, uterine anomalies, and antiphospholipid syndrome (APS) to RPL. In contrast, the relationship between RPL and
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Breastfeeding Initiation, Duration, and Associated Factors Among People With Hepatitis C Virus Infection. Obstet. Gynecol. (IF 7.2) Pub Date : 2024-01-04 Jennifer L Grasch, Jessica A de Voest, George R Saade, Brenna L Hughes, Uma M Reddy, Maged M Costantine, Edward K Chien, Alan T N Tita, John M Thorp, Torri D Metz, Ronald J Wapner, Vishakha Sabharwal, Hyagriv N Simhan, Geeta K Swamy, Kent D Heyborne, Baha M Sibai, William A Grobman, Yasser Y El-Sayed, Brian M Casey, Samuel Parry
To characterize breastfeeding behaviors and identify factors associated with breastfeeding initiation among people with hepatitis C virus (HCV) infection.