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“It’s a vote for hope”: first gene therapy for muscular dystrophy nears approval, but will it work? Nature (IF 69.504) Pub Date : 2023-06-02
The FDA’s decision, expected this month, follows several setbacks and delays and will pose difficult choices for the families of children with Duchenne muscular dystrophy.
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Colombia’s ‘cocaine hippo’ population is even bigger than scientists thought Nature (IF 69.504) Pub Date : 2023-06-02
The most comprehensive census yet reveals that there could be twice as many of the invasive animals than previous estimates indicated.
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Epic voyage finds astonishing microbial diversity among coral reefs Nature (IF 69.504) Pub Date : 2023-06-02
World’s largest survey of Pacific corals clocked 100,000 kilometres, collecting 58,000 samples from 249 locations including Indonesia, Japan and Papua New Guinea.
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Differences in the associations between psychoactive substance use and alexithymia: A series of meta-analyses Clin. Psychol. Rev. (IF 11.397) Pub Date : 2023-06-02 Bernadette Kun, Pelin Alpay, Viktória Bodó, Ágnes Molnár, Andrea Horváth, Szilvia Karsai, Róza Sára Somlai, Zsofia K. Takacs, Gyöngyi Kökönyei
The present meta-analytic study examined the association between alexithymia and psychoactive substance use. Studies published from 1988 to August 20, 2022 were identified by a systematic search and 168 eligible studies were included in five meta-analyses. Results showed that (1) the correlation between substance use and alexithymia is small but significant (r = 0.177); (2) substance users have substantially
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The mortality revolution, and the myth of the market: Books in brief Nature (IF 69.504) Pub Date : 2023-06-02
Andrew Robinson reviews five of the best science picks.
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How to make the workplace fairer for female researchers Nature (IF 69.504) Pub Date : 2023-06-02
Nature marked International Women’s Day by asking readers how to achieve gender equality in science.
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EU council’s ‘no pay’ publishing model draws mixed response Nature (IF 69.504) Pub Date : 2023-06-02
Some academics have welcomed the proposed open-access plans. But publishing-industry representatives warn they are unrealistic and lack detail.
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How to deliver a safer research culture for LGBTQIA+ researchers Nature (IF 69.504) Pub Date : 2023-06-02
Scientists from these communities mark the start of Pride Month by describing how colleagues and collaborators can better support them in lab and fieldwork settings.
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A storm is whirling atop Uranus Nature (IF 69.504) Pub Date : 2023-06-01
Strongly flowing winds are detected inside a bright spot at the giant planet’s north pole.
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Arab world's first asteroid hopper will visit seven space rocks Nature (IF 69.504) Pub Date : 2023-06-01
UAE's MBR Explorer aims to solve mystery of ultra-red celestial body in the asteroid belt beyond Mars.
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Biggest ever study of primate genomes has surprises for humanity Nature (IF 69.504) Pub Date : 2023-06-01
Genomes of humans' closest relatives provide insight for conservation, human disease and the origins of social structures.
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Preprint clubs: why it takes a village to do peer review Nature (IF 69.504) Pub Date : 2023-06-01
A group of early-career researchers have harnessed cross-institutional journal clubs to assess and review immunology preprints.
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Daily briefing: We are exceeding the limits of Earth’s ability to support us Nature (IF 69.504) Pub Date : 2023-06-01
Humanity has crossed eight of nine ‘Earth-system boundaries’ for a healthy and fair world. Plus, the brain’s wrinkles help to drive how it works and an infinite tiling pattern that could end a 60-year mathematical quest.
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Thousands of early-career NIH researchers forming union for first time Nature (IF 69.504) Pub Date : 2023-06-01
US push for better pay and benefits among scientists arrives at world’s largest biomedical funder.
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Global plan for dealing with next pandemic just got weaker, critics say Nature (IF 69.504) Pub Date : 2023-06-01
Watered-down language in the latest draft of the ‘pandemic treaty’ worries researchers.
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These hardy ants build their own landmarks in the desert Nature (IF 69.504) Pub Date : 2023-05-31
Ants living on the sprawling salt pans of Tunisia use DIY markers to find their way home.
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Daily briefing: Surveying the lush mosses of Canada’s Great Bear Rainforest Nature (IF 69.504) Pub Date : 2023-05-31
In a ‘bioblitz’, scientists catalogue the incredible diversity of bryophytes in a temperate rain forest. Plus, a ‘loss and damage’ fund for biodiversity and how chemists can now edit molecule cores atom by atom.
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Biased belief updating in depression Clin. Psychol. Rev. (IF 11.397) Pub Date : 2023-06-01 Tobias Kube
Cognitive approaches to depression have benefitted from recent research on belief updating, examining how new information is used to alter beliefs. This review presents recent advances in understanding various sources of bias in belief updating in depression. Specifically, research has demonstrated that people with depression have difficulty revising negative beliefs in response to novel positive information
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A systematic review of literature examining mediators and mechanisms of change in empirically supported treatments for posttraumatic stress disorder Clin. Psychol. Rev. (IF 11.397) Pub Date : 2023-06-01 Elizabeth Alpert, Chelsea Shotwell Tabke, Travis A. Cole, Daniel J. Lee, Denise M. Sloan
Despite the availability of empirically supported treatments (ESTs) for posttraumatic stress disorder (PTSD), relatively little is known regarding these treatments' mechanisms of change. This systematic review moves beyond previous reviews by summarizing the findings and reviewing the methodological quality of literature that specifically examined mediators/mechanisms of change in ESTs for PTSD. Studies
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Youth Advancing Anti-racism in the 2020s Current Opinion in Psychology (IF 6.813) Pub Date : 2023-06-01 Noelle M. Hurd, Madeline Brence, Claire Armstrong
In this review, we highlight articles on youth anti-racist action undertaken alongside the COVID-19 pandemic. Three contexts for youth anti-racism development are reviewed: educational settings, out-of-school programs, and youth-led participatory action research. The burden and costs of these undertakings are substantial for youth (particularly racially and ethnically marginalized youth), and pandemic-related
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The Psychological, Social, and Societal Relevance of Nostalgia Current Opinion in Psychology (IF 6.813) Pub Date : 2023-06-01 Constantine Sedikides, Tim Wildschut
Research on nostalgia has grown exponentially. This special issue features 27 articles that sketch out the relevant literature. The articles are arranged under five themes: Archaeological, historical, and sociological perspectives; the fundamentals of the emotion; psychological functions of nostalgia; varieties of nostalgia; and the social and societal significance of nostalgia. The introduction provides
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Impacts of COVID-19 Quarantine and Isolation on Adolescent Social Functioning Current Opinion in Psychology (IF 6.813) Pub Date : 2023-06-01 Rosanna Breaux, Annah R. Cash., Jasmine Lewis., Katelyn Garcia., Melissa R. Dvorsky., Stephen P. Becker.
This review discusses research conducted globally between March 2020 and March 2023 examining the impact of the COVID-19 pandemic on adolescent social functioning, including their lifestyle, extracurricular activities, family environment, peer environment, and social skills. Research highlights the widespread impact, with largely negative effects. However, a handful of studies support improved quality
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Responsiveness in Cultural-Ecological Context Current Opinion in Psychology (IF 6.813) Pub Date : 2023-06-01 Emre Selcuk, Gul Gunaydin
Theoretical and empirical research on responsiveness focused mostly on cultural ecologies of independence. Emerging studies suggest that the responsiveness process may unfold differently in cultural ecologies of interdependence. We organize these studies into a working conceptual model. The model argues that two mechanisms—expectations of culturally normative relationship behaviors and relative centrality
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This infinite tiling pattern could end a 60-year mathematical quest Nature (IF 69.504) Pub Date : 2023-06-01
First truly single aperiodic tile discovered that can cover an infinite surface without repeating itself.
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A broadband thermal emission spectrum of the ultra-hot Jupiter WASP-18b Nature (IF 69.504) Pub Date : 2023-05-31 Louis-Philippe Coulombe, Björn Benneke, Ryan Challener, Anjali A. A. Piette, Lindsey S. Wiser, Megan Mansfield, Ryan J. MacDonald, Hayley Beltz, Adina D. Feinstein, Michael Radica, Arjun B. Savel, Leonardo A. Dos Santos, Jacob L. Bean, Vivien Parmentier, Ian Wong, Emily Rauscher, Thaddeus D. Komacek, Eliza M.-R. Kempton, Xianyu Tan, Mark Hammond, Neil T. Lewis, Michael R. Line, Elspeth K. H. Lee, Hinna
Close-in giant exoplanets with temperatures greater than 2,000 K (“ultra-hot Jupiters”) have been the subject of extensive efforts to determine their atmospheric properties using thermal emission measurements from the Hubble and Spitzer Space Telescopes1–3. However, previous studies have yielded inconsistent results because the small sizes of the spectral features and the limited information content
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AI identifies gene interactions to speed up search for treatment targets Nature (IF 69.504) Pub Date : 2023-05-31
Hear the biggest stories from the world of science | 31 May 2023
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Transannular C–H functionalization of cycloalkane carboxylic acids Nature (IF 69.504) Pub Date : 2023-05-31 Guowei Kang, Daniel A. Strassfeld, Tao Sheng, Chia-Yu Chen, Jin-Quan Yu
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Deterministic evolution and stringent selection during preneoplasia Nature (IF 69.504) Pub Date : 2023-05-31 Kasper Karlsson, Moritz J. Przybilla, Eran Kotler, Aziz Khan, Hang Xu, Kremena Karagyozova, Alexandra Sockell, Wing H. Wong, Katherine Liu, Amanda Mah, Yuan-Hung Lo, Bingxin Lu, Kathleen E. Houlahan, Zhicheng Ma, Carlos J. Suarez, Chris P. Barnes, Calvin J. Kuo, Christina Curtis
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Axonemal structures reveal mechanoregulatory and disease mechanisms Nature (IF 69.504) Pub Date : 2023-05-31 Travis Walton, Miao Gui, Simona Velkova, Mahmoud R. Fassad, Robert A. Hirst, Eric Haarman, Christopher O’Callaghan, Mathieu Bottier, Thomas Burgoyne, Hannah M. Mitchison, Alan Brown
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Attosecond electron microscopy of sub-cycle optical dynamics Nature (IF 69.504) Pub Date : 2023-05-31 David Nabben, Joel Kuttruff, Levin Stolz, Andrey Ryabov, Peter Baum
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Expertise increases planning depth in human gameplay Nature (IF 69.504) Pub Date : 2023-05-31 Bas van Opheusden, Ionatan Kuperwajs, Gianni Galbiati, Zahy Bnaya, Yunqi Li, Wei Ji Ma
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Uncovering the Ediacaran phosphorus cycle Nature (IF 69.504) Pub Date : 2023-05-31 Matthew S. Dodd, Wei Shi, Chao Li, Zihu Zhang, Meng Cheng, Haodong Gu, Dalton S. Hardisty, Sean J. Loyd, Malcolm W. Wallace, Ashleigh vS. Hood, Kelsey Lamothe, Benjamin J. W. Mills, Simon W. Poulton, Timothy W. Lyons
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A pan-influenza antibody inhibiting neuraminidase via receptor mimicry Nature (IF 69.504) Pub Date : 2023-05-31 Corey Momont, Ha V. Dang, Fabrizia Zatta, Kevin Hauser, Caihong Wang, Julia di Iulio, Andrea Minola, Nadine Czudnochowski, Anna De Marco, Kaitlin Branch, David Donermeyer, Siddhant Vyas, Alex Chen, Elena Ferri, Barbara Guarino, Abigail E. Powell, Roberto Spreafico, Samantha S. Yim, Dale R. Balce, Istvan Bartha, Marcel Meury, Tristan I. Croll, David M. Belnap, Michael A. Schmid, William Timothy Schaiff
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Increasingly negative tropical water–interannual CO2 growth rate coupling Nature (IF 69.504) Pub Date : 2023-05-31 Laibao Liu, Philippe Ciais, Mengxi Wu, Ryan S. Padrón, Pierre Friedlingstein, Jonas Schwaab, Lukas Gudmundsson, Sonia I. Seneviratne
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Characterization of just one atom using synchrotron X-rays Nature (IF 69.504) Pub Date : 2023-05-31 Tolulope M. Ajayi, Nozomi Shirato, Tomas Rojas, Sarah Wieghold, Xinyue Cheng, Kyaw Zin Latt, Daniel J. Trainer, Naveen K. Dandu, Yiming Li, Sineth Premarathna, Sanjoy Sarkar, Daniel Rosenmann, Yuzi Liu, Nathalie Kyritsakas, Shaoze Wang, Eric Masson, Volker Rose, Xiaopeng Li, Anh T. Ngo, Saw-Wai Hla
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Enhanced rare-earth separation with a metal-sensitive lanmodulin dimer Nature (IF 69.504) Pub Date : 2023-05-31 Joseph A. Mattocks, Jonathan J. Jung, Chi-Yun Lin, Ziye Dong, Neela H. Yennawar, Emily R. Featherston, Christina S. Kang-Yun, Timothy A. Hamilton, Dan M. Park, Amie K. Boal, Joseph A. Cotruvo
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Transfer learning enables predictions in network biology Nature (IF 69.504) Pub Date : 2023-05-31 Christina V. Theodoris, Ling Xiao, Anant Chopra, Mark D. Chaffin, Zeina R. Al Sayed, Matthew C. Hill, Helene Mantineo, Elizabeth M. Brydon, Zexian Zeng, X. Shirley Liu, Patrick T. Ellinor
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Strong and ductile titanium–oxygen–iron alloys by additive manufacturing Nature (IF 69.504) Pub Date : 2023-05-31 Tingting Song, Zibin Chen, Xiangyuan Cui, Shenglu Lu, Hansheng Chen, Hao Wang, Tony Dong, Bailiang Qin, Kang Cheung Chan, Milan Brandt, Xiaozhou Liao, Simon P. Ringer, Ma Qian
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In situ tumour arrays reveal early environmental control of cancer immunity Nature (IF 69.504) Pub Date : 2023-05-31 Guadalupe Ortiz-Muñoz, Markus Brown, Catherine B. Carbone, Ximo Pechuan-Jorge, Vincent Rouilly, Henrik Lindberg, Alex T. Ritter, Gautham Raghupathi, Qianbo Sun, Tess Nicotra, Shreya R. Mantri, Angela Yang, Jonas Doerr, Deepti Nagarkar, Spyros Darmanis, Benjamin Haley, Sanjeev Mariathasan, Yulei Wang, Carlos Gomez-Roca, Carlos Eduardo de Andrea, David Spigel, Thomas Wu, Lelia Delamarre, Johannes Schöneberg
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Myelin dysfunction drives amyloid-β deposition in models of Alzheimer’s disease Nature (IF 69.504) Pub Date : 2023-05-31 Constanze Depp, Ting Sun, Andrew Octavian Sasmita, Lena Spieth, Stefan A. Berghoff, Taisiia Nazarenko, Katharina Overhoff, Agnes A. Steixner-Kumar, Swati Subramanian, Sahab Arinrad, Torben Ruhwedel, Wiebke Möbius, Sandra Göbbels, Gesine Saher, Hauke B. Werner, Alkmini Damkou, Silvia Zampar, Oliver Wirths, Maik Thalmann, Mikael Simons, Takashi Saito, Takaomi Saido, Dilja Krueger-Burg, Riki Kawaguchi
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The effects of cash transfers on adult and child mortality in low- and middle-income countries Nature (IF 69.504) Pub Date : 2023-05-31 Aaron Richterman, Christophe Millien, Elizabeth F. Bair, Gregory Jerome, Jean Christophe Dimitri Suffrin, Jere R. Behrman, Harsha Thirumurthy
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Pan-KRAS inhibitor disables oncogenic signalling and tumour growth Nature (IF 69.504) Pub Date : 2023-05-31 Dongsung Kim, Lorenz Herdeis, Dorothea Rudolph, Yulei Zhao, Jark Böttcher, Alberto Vides, Carlos I. Ayala-Santos, Yasin Pourfarjam, Antonio Cuevas-Navarro, Jenny Y. Xue, Andreas Mantoulidis, Joachim Bröker, Tobias Wunberg, Otmar Schaaf, Johannes Popow, Bernhard Wolkerstorfer, Katrin Gabriele Kropatsch, Rui Qu, Elisa de Stanchina, Ben Sang, Chuanchuan Li, Darryl B. McConnell, Norbert Kraut, Piro Lito
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Indefinite and bidirectional near-infrared nanocrystal photoswitching Nature (IF 69.504) Pub Date : 2023-05-31 Changhwan Lee, Emma Z. Xu, Kevin W. C. Kwock, Ayelet Teitelboim, Yawei Liu, Hye Sun Park, Benedikt Ursprung, Mark E. Ziffer, Yuzuka Karube, Natalie Fardian-Melamed, Cassio C. S. Pedroso, Jongwoo Kim, Stefanie D. Pritzl, Sang Hwan Nam, Theobald Lohmueller, Jonathan S. Owen, Peter Ercius, Yung Doug Suh, Bruce E. Cohen, Emory M. Chan, P. James Schuck
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Nuclear export of pre-60S particles through the nuclear pore complex Nature (IF 69.504) Pub Date : 2023-05-31 Zongqiang Li, Shuaijiabin Chen, Liang Zhao, Guoqiang Huang, Huiqin Xu, Xiaoyun Yang, Peiyi Wang, Ning Gao, Sen-Fang Sui
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Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours Nature (IF 69.504) Pub Date : 2023-05-31 Avishai Gavish, Michael Tyler, Alissa C. Greenwald, Rouven Hoefflin, Dor Simkin, Roi Tschernichovsky, Noam Galili Darnell, Einav Somech, Chaya Barbolin, Tomer Antman, Daniel Kovarsky, Thomas Barrett, L. Nicolas Gonzalez Castro, Debdatta Halder, Rony Chanoch-Myers, Julie Laffy, Michael Mints, Adi Wider, Rotem Tal, Avishay Spitzer, Toshiro Hara, Maria Raitses-Gurevich, Chani Stossel, Talia Golan, Amit
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Safe and just Earth system boundaries Nature (IF 69.504) Pub Date : 2023-05-31 Johan Rockström, Joyeeta Gupta, Dahe Qin, Steven J. Lade, Jesse F. Abrams, Lauren S. Andersen, David I. Armstrong McKay, Xuemei Bai, Govindasamy Bala, Stuart E. Bunn, Daniel Ciobanu, Fabrice DeClerck, Kristie Ebi, Lauren Gifford, Christopher Gordon, Syezlin Hasan, Norichika Kanie, Timothy M. Lenton, Sina Loriani, Diana M. Liverman, Awaz Mohamed, Nebojsa Nakicenovic, David Obura, Daniel Ospina, Klaudia
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Geometric constraints on human brain function Nature (IF 69.504) Pub Date : 2023-05-31 James C. Pang, Kevin M. Aquino, Marianne Oldehinkel, Peter A. Robinson, Ben D. Fulcher, Michael Breakspear, Alex Fornito
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Engineered tRNAs suppress nonsense mutations in cells and in vivo Nature (IF 69.504) Pub Date : 2023-05-31 Suki Albers, Elizabeth C. Allen, Nikhil Bharti, Marcos Davyt, Disha Joshi, Carlos G. Perez-Garcia, Leonardo Santos, Rajesh Mukthavaram, Miguel Angel Delgado-Toscano, Brandon Molina, Kristen Kuakini, Maher Alayyoubi, Kyoung-Joo Jenny Park, Grishma Acharya, Jose A. Gonzalez, Amit Sagi, Susan E. Birket, Guillermo J. Tearney, Steven M. Rowe, Candela Manfredi, Jeong S. Hong, Kiyoshi Tachikawa, Priya Karmali
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The geometry of the human brain shapes its function Nature (IF 69.504) Pub Date : 2023-05-31
A physically principled framework shows that the brain’s geometry has a greater influence on neural activity patterns than the complex interconnectivity between brain regions.
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AI intensifies fight against ‘paper mills’ that churn out fake research Nature (IF 69.504) Pub Date : 2023-05-31
Text- and image-generating tools present a new hurdle for efforts to tackle the growing number of fake papers making their way into the academic literature.
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Cash-transfer programmes reduce mortality in low- and middle-income countries Nature (IF 69.504) Pub Date : 2023-05-31
Risk of death among women and young children was markedly reduced by the poverty-reduction efforts.
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Search for distant atmosphere off to a rocky start Nature (IF 69.504) Pub Date : 2023-05-31 Laura Kreidberg
JWST observations rule out atmosphere for TRAPPIST-1b.
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How to define unjust planetary change Nature (IF 69.504) Pub Date : 2023-05-31 Stephen Humphreys
Safe and just boundaries for Earth.
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How a protein differentiates between rare-earth elements Nature (IF 69.504) Pub Date : 2023-05-31 Scott Banta
Structures and metal-binding modes of lanmodulin proteins.
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The human brain’s characteristic wrinkles help to drive how it works Nature (IF 69.504) Pub Date : 2023-05-31
A model of the brain’s geometry better explains neuronal activity than a model based on the ‘connectome’.
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Patterns of tumour transcriptional variability Nature (IF 69.504) Pub Date : 2023-05-31 Raymond W. S. Ng, Sydney M. Shaffer
Analysis of single-cell RNA-sequencing studies across various cancers.
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A structural model of the core of cilia Nature (IF 69.504) Pub Date : 2023-05-31
An atomic model of the axoneme core of the hair-like cilia on some cells reveals how they move.
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Machine-learning model makes predictions about network biology Nature (IF 69.504) Pub Date : 2023-05-31
Pretraining on a large data set gives model insight into how genes interact.
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Why ideas of ‘planetary boundaries’ must uphold environmental justice Nature (IF 69.504) Pub Date : 2023-05-31
Earth-system boundaries define a safe operating space for humanity. Accounting for the planet’s most vulnerable people provides a stark warning of the work still to be done.'
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Designer titanium alloys created using 3D printing Nature (IF 69.504) Pub Date : 2023-05-31
Strong and ductile titanium–oxygen–iron alloys made using a laser-directed additive-manufacturing process.