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Exploring the synergy of enhanced weathering and Bacillus subtilis: A promising strategy for sustainable agriculture Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-18 Harun Niron, Arthur Vienne, Patrick Frings, Reinaldy Poetra, Sara Vicca
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Land use drives the distribution of free, physically protected, and chemically protected soil organic carbon storage at a global scale Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-18 Samuel J. Willard, Guopeng Liang, Savannah Adkins, Karen Foley, Jessica Murray, Bonnie Waring
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Mind the gap between education policy and practice Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-19 Noam Angrist, Stefan Dercon
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Challenges in developing STEM sign language for inclusive education Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-19 Caroline M. Solomon
Caroline Solomon is a biological oceanographer and deaf. She discusses how STEM sign lexicon development contributes to inclusive education and which challenges still need to be overcome.
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Replay shapes abstract cognitive maps for efficient social navigation Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-19 Jae-Young Son, Marc-Lluís Vives, Apoorva Bhandari, Oriel FeldmanHall
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Reply to: Milk intake, lactase non-persistence and type 2 diabetes risk in Chinese adults Nat. Metab. (IF 18.9) Pub Date : 2024-09-18 Kai Luo, Yanbo Zhang, Robert C. Kaplan, Qibin Qi
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Milk intake, lactase non-persistence and type 2 diabetes risk in Chinese adults Nat. Metab. (IF 18.9) Pub Date : 2024-09-18 Maria G. Kakkoura, Robin G. Walters, Robert Clarke, Zhengming Chen, Huaidong Du
arising from K. Luo et al. Nature Metabolism https://doi.org/10.1038/s42255-023-00961-1 (2024) In the 2024 January issue of Nature Metabolism, Luo et al.1 reported an inverse association between milk intake and risk of type 2 diabetes (T2D) among individuals who were lactase non-persistent (LNP), as determined by the lactase (LCT) rs4988235 homozygous GG genotype. The authors also reported inverse
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Ethical challenges in translating brain–computer interfaces Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-17 Anna Wexler, Ashley Feinsinger
Brain–computer interfaces (BCIs) have the potential to revolutionize treatment for individuals with severe disabilities. As these technologies transition from the laboratory to real-world applications, they pose unique ethical challenges that necessitate careful consideration.
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Observational and genetic evidence disagree on the association between loneliness and risk of multiple diseases Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-16 Yannis Yan Liang, Mingqing Zhou, Yu He, Weijie Zhang, Qiqi Wu, Tong Luo, Jun Zhang, Fujun Jia, Lu Qi, Sizhi Ai, Jihui Zhang
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Fetal bone engraftment reconstitutes the immune system in pigs with severe combined immunodeficiency Lab Anim. (IF 5.9) Pub Date : 2024-09-17 Kaylynn Monarch, Junchul Yoon, Kyungjun Uh, Emily Reese, Diana Canaveral Restrepo, Darling Melany de Carvalho Madrid, Laurie Touchard, Lee D. Spate, Melissa S. Samuel, John P. Driver, Ji-Hey Lim, Sarah Schlink, Kristin M. Whitworth, Kevin D. Wells, Randall S. Prather, Paula R. Chen, Kiho Lee
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Patient Consent and The Right to Notice and Explanation of AI Systems Used in Health Care. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-17 Meghan E Hurley,Benjamin H Lang,Kristin Marie Kostick-Quenet,Jared N Smith,Jennifer Blumenthal-Barby
Given the need for enforceable guardrails for artificial intelligence (AI) that protect the public and allow for innovation, the U.S. Government recently issued a Blueprint for an AI Bill of Rights which outlines five principles of safe AI design, use, and implementation. One in particular, the right to notice and explanation, requires accurately informing the public about the use of AI that impacts
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Some Extensions of the Loop: A Response to the Comments on Machine Learning-Driven Decision Aids. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-17 Sabine Salloch,Andreas Eriksen
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Changing disturbance regimes, material legacies, and stabilizing feedbacks: Dead coral skeletons impair key recovery processes following coral bleaching Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-16 Kai L. Kopecky, Sally J. Holbrook, Emalia Partlow, Madeline Cunningham, Russell J. Schmitt
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Adaptive Machine Learning Systems in Medicine - More Learner, Less Machine. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Anthony P Weiss
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Adaptive Machine Learning Systems in Medicine: The Post-Authorization Phase. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Katrina A Bramstedt,Timothé Ménard
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Bolder Bioethics: Demanding a Gold Standard in REDI Recommendations. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Kumeri Bandara,Harleen Kaur Johal,Matimba Swana
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Designing Regulatory Frameworks for Machine Learning Systems in Medicine-Time for Balance and Practicality. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Junaid Nabi,Tawheed Makhdoomi
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Achieving Live Birth is Not an Endpoint but a Steppingstone. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Lainie Friedman Ross,Amy Gallo,D Micah Hester
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Beyond Consent: The MAMLS in the Room. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Jimin Rhim,Hortense Gallois,Vardit Ravitsky,Jean-Christophe Bélisle-Pipon
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Prudently Evaluating Medical Adaptive Machine Learning Systems. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Andreas Kuersten
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Discerning the Nature of MAMLS: Research, Quality Improvement, or Both? Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Charles Binkley,Rohan Meda,Joel de Lara
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REDI in Bioethics Cannot Be Achieved Without the Promotion of Anti-Ableism. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Kevin Todd Mintz,Maya Sabatello
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The Need for an Evolving Informed Consent Process in a Fetal Therapy Trial. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Meredith A Atkinson,Erika Ezumba,Jena L Miller
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Learning From Those Who Were Not REDI. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Jed Adam Gross,Karen Devon,Carol-Anne Moulton,Stephen Reich
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REDI in Practice: A Need to Expand Our Knowledge Pool. Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-16 Kimberly Vargas Barreto
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Online misinformation warning labels work despite distrust of fact-checkers Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-13
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The influence of habitat alteration on density of invading white‐tailed deer should not be discounted Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-13 Andrew Barnas, Brad Anholt, A. Cole Burton, Kathleen Carroll, Steeve D. Côté, Marco Festa‐Bianchet, John Fryxell, Martin‐Hugues St‐Laurent, Jason T. Fisher
Growing white‐tailed deer populations in Canada's boreal forest are linked to declines of threatened boreal caribou populations. Recent work by Dickie et al. (2024) shows that climate plays a stronger role than anthropogenic habitat alteration in impacting deer white‐tailed deer density, however we contend that these findings are not robust due to insufficient data and the analysis used is sensitive
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Precipitation and temperature timings underlying bioclimatic variables rearrange under climate change globally Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-13 Ákos Bede‐Fazekas, Imelda Somodi
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The influence of habitat alteration is widespread, but the impact of climate cannot continue to be discounted Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-13 Melanie Dickie, Robert Serrouya, Marcus Becker, Craig DeMars, Michael J. Noonan, Robin Steenweg, Stan Boutin, Adam T. Ford
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How do drought and heat affect the response of soybean seed yield to elevated O3? An analysis of 15 seasons of free‐air O3 concentration enrichment studies Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-12 Shuai Li, Christopher M. Montes, Elise K. Aspray, Elizabeth A. Ainsworth
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PPARγ drives mitochondrial stress signaling and the loss of atrial cardiomyocytes in newborn mice exposed to hyperoxia Redox Biol. (IF 10.7) Pub Date : 2024-09-12 E. David Cohen, Kyle Roethlin, Min Yee, Collynn F. Woeller, Paul S. Brookes, George A. Porter Jr., Michael A. O'Reilly
Diastolic dysfunction is increasingly common in preterm infants exposed to supplemental oxygen (hyperoxia). Previous studies in neonatal mice showed hyperoxia suppresses fatty acid synthesis genes required for proliferation and survival of atrial cardiomyocytes. The loss of atrial cardiomyocytes creates a hypoplastic left atrium that inappropriately fills the left ventricle during diastole. Here, we
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O-GlcNAc transferase regulates glycolytic metabolon formation on mitochondria to enhance ATP production Nat. Metab. (IF 18.9) Pub Date : 2024-09-11
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Organization of a functional glycolytic metabolon on mitochondria for metabolic efficiency Nat. Metab. (IF 18.9) Pub Date : 2024-09-11 Haoming Wang, John W. Vant, Andrew Zhang, Richard G. Sanchez, Youjun Wu, Mary L. Micou, Vincent Luczak, Zachary Whiddon, Natasha M. Carlson, Seungyoon B. Yu, Mirna Jabbo, Seokjun Yoon, Ahmed A. Abushawish, Majid Ghassemian, Takeya Masubuchi, Quan Gan, Shigeki Watanabe, Eric R. Griffis, Marc Hammarlund, Abhishek Singharoy, Gulcin Pekkurnaz
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Targeting GPX4-mediated ferroptosis protection sensitizes BRCA1-deficient cancer cells to PARP inhibitors Redox Biol. (IF 10.7) Pub Date : 2024-09-11 Xuexia Xie, Congcong Chen, Cong Wang, Yongjian Guo, Binghe Sun, Jiaxin Tian, Jin Yan, Dake Li, Guo Chen
is one of the most frequently-mutated tumor suppressor genes in ovarian and breast cancers. Loss of BRCA1 triggers homologous recombination (HR) repair deficiency, consequently leading to genomic instability and PARP inhibitors (PARPi)-associated synthetic lethality. Although, the roles of BRCA1 in DNA repair and replication have been extensively investigated, its tumor suppressive functions beyond
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Long-term exercise training has positive effects on adipose tissue in overweight or obesity Nat. Metab. (IF 18.9) Pub Date : 2024-09-10
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Years of endurance exercise training remodel abdominal subcutaneous adipose tissue in adults with overweight or obesity Nat. Metab. (IF 18.9) Pub Date : 2024-09-10 Cheehoon Ahn, Tao Zhang, Gayoung Yang, Thomas Rode, Pallavi Varshney, Sophia J. Ghayur, Olivia K. Chugh, Hui Jiang, Jeffrey F. Horowitz
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More sensitive microbial responses to the interactive effects of warming and altered precipitation in subsoil than topsoil of an alpine grassland ecosystem Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-10 Qi Qi, Shijie Ning, Xue Guo, Jianshu Zhao, Renmao Tian, Haoran Gui, Jin‐Sheng He, Hao Wang, Zhenhua Zhang, Konstantinos T. Konstantinidis, Qun Gao, Yuxin Wang, Shunyi Li, Weishu Zhao, Yunfeng Yang, Jizhong Zhou
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Males miss and females forgo: Auditory masking from vessel noise impairs foraging efficiency and success in killer whales Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-10 Jennifer B. Tennessen, Marla M. Holt, Brianna M. Wright, M. Bradley Hanson, Candice K. Emmons, Deborah A. Giles, Jeffrey T. Hogan, Sheila J. Thornton, Volker B. Deecke
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Positive soil priming effects are the rule at a global scale Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-10 Shengwen Xu, Manuel Delgado‐Baquerizo, Yakov Kuzyakov, Yan Wu, Lihu Liu, Yuyi Yang, Yaying Li, Yongxiang Yu, Biao Zhu, Huaiying Yao
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UBR5 mediates colorectal cancer chemoresistance by attenuating ferroptosis via Lys 11 ubiquitin-dependent stabilization of Smad3-SLC7A11 signaling Redox Biol. (IF 10.7) Pub Date : 2024-09-10 Mei Song, Shuting Huang, Xiaoxue Wu, Ziyi Zhao, Xiaoting Liu, Chong Wu, Mengru Wang, Jialing Gao, Zunfu Ke, Xiaojing Ma, Weiling He
Chemoresistance remains a principal culprit for the treatment failure in colorectal cancer (CRC), especially for patients with recurrent or metastatic disease. Deciphering the molecular basis of chemoresistance may lead to novel therapeutic strategies for this fatal disease. Here, UBR5, an E3 ubiquitin ligase frequently overexpressed in human CRC, is demonstrated to mediate chemoresistance principally
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Spatial single-cell isotope tracing reveals heterogeneity of de novo fatty acid synthesis in cancer Nat. Metab. (IF 18.9) Pub Date : 2024-09-09 Elena Buglakova, Måns Ekelöf, Michaela Schwaiger-Haber, Lisa Schlicker, Martijn R. Molenaar, Mohammed Shahraz, Lachlan Stuart, Andreas Eisenbarth, Volker Hilsenstein, Gary J. Patti, Almut Schulze, Marteinn T. Snaebjornsson, Theodore Alexandrov
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What we should learn from pandemic publishing Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-09 Satyaki Sikdar, Sara Venturini, Marie-Laure Charpignon, Sagar Kumar, Francesco Rinaldi, Francesco Tudisco, Santo Fortunato, Maimuna S. Majumder
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Distributed representations of behaviour-derived object dimensions in the human visual system Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-09 Oliver Contier, Chris I. Baker, Martin N. Hebart
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Temperature controls the relation between soil organic carbon and microbial carbon use efficiency Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-09 Zhaoyang Luo, Jianning Ren, Stefano Manzoni, Simone Fatichi
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The limits of the metapopulation: Lineage fragmentation in a widespread terrestrial salamander (Plethodon cinereus) Syst. Biol. (IF 6.1) Pub Date : 2024-09-09 Brian P Waldron, Emily F Watts, Donald J Morgan, Maggie M Hantak, Alan R Lemmon, Emily Moriarty Lemmon, Shawn R Kuchta
In vicariant species formation, divergence results primarily from periods of allopatry and restricted gene flow. Widespread species harboring differentiated, geographically distinct sublineages offer a window into what may be a common mode of species formation, whereby a species originates, spreads across the landscape, then fragments into multiple units. However, incipient lineages usually lack reproductive
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Water restriction alters seed bank traits and ecology in Atlantic Forest seasonal forests under climate change Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-07 Patrícia Borges Dias, Sustanis Horn Kunz, José Eduardo Macedo Pezzopane, Talita Miranda Teixeira Xavier, João Paulo Fernandes Zorzanelli, João Vitor Toledo, Lhoraynne Pereira Gomes, Rodrigo Gomes Gorsani
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LOX-mediated ECM mechanical stress induces Piezo1 activation in hypoxic-ischemic brain damage and identification of novel inhibitor of LOX Redox Biol. (IF 10.7) Pub Date : 2024-09-07 Dongya Jiang, Jing Zhao, Jie Zheng, Yingmin Zhao, Meini Le, Dani Qin, Qiong Huang, Jinyu Huang, Qingshun Zhao, Long Wang, Xiaohua Dong
Hypoxic-ischemic encephalopathy (HIE) poses a significant challenge in neonatal medicine, often resulting in profound and lasting neurological deficits. Current therapeutic strategies for hypoxia-ischemia brain damage (HIBD) remain limited. Ferroptosis has been reported to play a crucial role in HIE and serves as a potential therapeutic target. However, the mechanisms underlying ferroptosis in HIBD
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High expression levels of haem oxygenase-1 promote ferroptosis in macrophage-derived foam cells and exacerbate plaque instability Redox Biol. (IF 10.7) Pub Date : 2024-09-07 Zhenyu Guo, Wan Zhang, Hongxia Gao, Yang Li, Xu Li, Xiaohu Yang, Longhua Fan
Plaque rupture with consequent thrombosis is the leading cause of acute cardiovascular events, during which macrophage death is a hallmark. Ferroptosis is a pivotal intermediate link between early and advanced atherosclerosis. Existing evidence indicates the involvement of macrophage ferroptosis in plaque vulnerability; however, the exact mechanism remains elusive. The aim of this study was to explore
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Efferocytosis drives a tryptophan metabolism pathway in macrophages to promote tissue resolution Nat. Metab. (IF 18.9) Pub Date : 2024-09-06 Santosh R. Sukka, Patrick B. Ampomah, Lancia N. F. Darville, David Ngai, Xiaobo Wang, George Kuriakose, Yuling Xiao, Jinjun Shi, John M. Koomen, Robert H. McCusker, Ira Tabas
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Preventing eating disorders in the LGBTQ+ community Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-06 Jaclyn A. Siegel, Michelle M. Johns
To prevent eating disorders in the LGBTQ+ (lesbian, gay, bisexual, transgender, queer) community, we must enact safeguards for sexual and gender minority individuals to live in their bodies authentically, address stigma against and within the LGBTQ+ community, and fund research to develop a better understanding of the unique drivers of eating disorder behaviours and to tailor prevention efforts.
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Common neural choice signals can emerge artefactually amid multiple distinct value signals Nat. Hum. Behav. (IF 21.4) Pub Date : 2024-09-06 Romy Frömer, Matthew R. Nassar, Benedikt V. Ehinger, Amitai Shenhav
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Knowing You Know Better Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-03 Robert Steel
Published in The American Journal of Bioethics (Vol. 24, No. 9, 2024)
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Early AI Lifecycle Co-Reasoning: Ethics Through Integrated and Diverse Team Science Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-03 Danielle M. Pacia, Vardit Ravitsky, Jan N. Hansen, Emma Lundberg, Wade Schulz, Jean-Christophe Bélisle-Pipon
Published in The American Journal of Bioethics (Vol. 24, No. 9, 2024)
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Reasons in the Loop: The Role of Large Language Models in Medical Co-Reasoning Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-03 Sebastian Porsdam Mann, Brian D. Earp, Peng Liu, Julian Savulescu
Published in The American Journal of Bioethics (Vol. 24, No. 9, 2024)
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The Black Box Dilemma: Challenges in Human-AI Collaboration in ML-CDSS Am. J. Bioethics (IF 17.0) Pub Date : 2024-09-03 Rishab Jain, Rushil Srirambhatla, John Kessler, Ram Goel
Published in The American Journal of Bioethics (Vol. 24, No. 9, 2024)
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Adaptation to climate change and limits in food production systems: Physics, the chemistry of biology, and human behavior Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-06 Gerald C. Nelson, William W. L. Cheung, Rachel Bezner Kerr, James Franke, Francisco Meza, Muhammed A. Oyinlola, Philip Thornton, Florian Zabel
Are there limits to our ability to adapt food systems to climate change? This overview paper for the special issue highlights results of research on potential limits and responses by food system actors. Responses are shaped by the critical interactions among the physical, chemical, biological, and social impacts in food systems arising from climate change. Food grains, temperate perennials, livestock
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Tall Bornean forests experience higher canopy disturbance rates than those in the eastern Amazon or Guiana shield Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-06 Toby D. Jackson, Fabian J. Fischer, Grégoire Vincent, Eric B. Gorgens, Michael Keller, Jérôme Chave, Tommaso Jucker, David A. Coomes
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The devil is in the details: Experiment reveals how a forest‐dwelling scavenger, and their excrement, may buffer ecosystem processes from climate change Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-06 Thomas D. Stokely
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Global change and premature hatching of aquatic embryos Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-06 Zara‐Louise Cowan, Leon Green, Timothy D. Clark, Tamzin A. Blewett, Jeremy De Bonville, Thomas Gagnon, Elizabeth Hoots, Luis Kuchenmüller, Robine H. J. Leeuwis, Joaquín Navajas Acedo, Lauren E. Rowsey, Hanna Scheuffele, Michael Richard Skeeles, Lorena Silva‐Garay, Fredrik Jutfelt, Sandra A. Binning
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Otolith reliability is context‐dependent for estimating warming and CO2 acidification impacts on fish growth Glob. Change Biol. (IF 10.8) Pub Date : 2024-09-06 Bangli Tang, Liuyong Ding, Chengzhi Ding, Dekui He, Haojie Su, Juan Tao