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Development of a Pseudocellular System to Quantify Specific Interactions Determining the G-Quadruplex Function in Cells J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Hisae Tateishi-Karimata, Keiko Kawauchi, Shuntaro Takahashi, Naoki Sugimoto
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Superconductivity and Charge-Density-Wave-Like Transition in Th2Cu4As5 J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Shaohua Liu, Qingchen Duan, Baizhuo Li, Jiaojiao Meng, Wuzhang Yang, Yi Liu, Yi-Qiang Lin, Si-Qi Wu, Jiayi Lu, Jin-Ke Bao, Yusen Xiao, Xinyu Zhao, Yu-Xue Mei, Yuping Sun, Shugang Tan, Qiang Jing, Dan Yu, Ruidan Zhong, Yongliang Chen, Yong Zhao, Zhi Ren, Cao Wang, Guang-Han Cao
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How Concerted Are Ionic Hops in Inorganic Solid-State Electrolytes? J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Cibrán López, Riccardo Rurali, Claudio Cazorla
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Red Light–Blue Light Chromoselective C(sp2)–X Bond Activation by Organic Helicenium-Based Photocatalysis J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Md Mubarak Hossain, Aslam C. Shaikh, Ramandeep Kaur, Thomas L. Gianetti
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Platform for Multiple Isotope Labeling via Carbon–Sulfur Bond Exchange J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Bouchaib Mouhsine, Maylis Norlöff, Juba Ghouilem, Antoine Sallustrau, Frédéric Taran, Davide Audisio
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Light in a Heartbeat: Bond Scission by a Single Photon above 800 nm J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Marina Russo, Hana Janeková, Debora Meier, Melanie Generali, Peter Štacko
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Ion Mobility Mass Spectrometry for Large Synthetic Molecules: Expanding the Analytical Toolbox J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Niklas Geue, Richard E. P. Winpenny, Perdita E. Barran
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Ion Pairing Enables Targeted Prodrug Activation via Red Light Photocatalysis: A Proof-of-Concept Study with Anticancer Gold Complexes J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Zhiying Xie, Bei Cao, Jing Zhao, Moyi Liu, Yuhan Lao, Hejiang Luo, Zhi Zhong, Xiaolin Xiong, Wei Wei, Taotao Zou
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Mechanistic Investigation into Single-Electron Oxidative Addition of Single-Atom Cu(I)-N4 Site: Revealing the Cu(I)–Cu(II)–Cu(I) Catalytic Cycle in Photochemical Hydrophosphinylation J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Guanglin Wang, Yichang Liu, Xiangyu Zhang, Xupeng Zong, Xu Zhang, Kun Zheng, Dan Qu, Li An, Xiaotian Qi, Zaicheng Sun
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Isolation of Cationic η3-Allenylnickel(II) Key Intermediate Complexes: Origins of Enantioselectivity and Regioselectivity in Nickel(0)-Catalyzed Asymmetric Propargylic Substitutions J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Yusuke Miyazaki, Kenichi Michigami, Masato Ohashi
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In Situ Visualization of RNA-Specific Sialylation on Living Cell Membranes to Explore N-Glycosylation Sites J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Huipu Liu, Xuemei Li, Yi Ren, Yuanjiao Yang, Yunlong Chen, Huangxian Ju
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Exploring Pyroelectricity, Thermal and Photochemical Switching in a Hybrid Organic-Inorganic Crystal by In-situ X-ray Diffraction Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Joshua J. Morris, Chris R. Bowen, Ben A. Coulson, Mark Eaton, Paul R. Raithby, Lucy K. Saunders, Jonathan M. Skelton, Qingping Wang, Mark R. Warren, Yan Zhang, Lauren Hatcher
The switching behavior of the novel hybrid material (FA)Na[Fe(CN)5(NO)].H2O (1) in response to temperature (T), light irradiation and electric field (E) is studied using in-situ X-ray diffraction (XRD). Crystals of 1 display piezoelectricity, pyroelectricity, second and third harmonic generation. XRD shows that the FA+ are disordered at room-temperature, but stepwise cooling from 273-100K induces gradual
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Stabilizing Lattice Oxygen through Mn Doping in NiCo2O4−d Spinel Electrocatalysts for Efficient and Durable Acid Oxygen Evolution Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Hongyu Zhao, Liu Zhu, Jie Yin, Jing Jin, Xin Du, Lei Tan, Yong Peng, Pinxian Xi, Chun-Hua Yan
Design the electrocatalysts without noble metal is still a challenge for oxygen evolution reaction (OER) in acid media. Herein, we reported the manganese doping method to decrease the concentration of oxygen vacancy (Vo) and form the Mn−O structure adjacent octahedral sites in spinel NiCo2O4−δ (NiMn1.5Co3O4−δ), which highly enhanced the activity and stability of spinel NiCo2O4−δ with a low overpotential
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Dimethyl Carbonate Synthesis from CO2 over CeO2 with Electron-enriched Lattice Oxygen Specises Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Guoqiang Hou, Qi Wang, Di Xu, Haifeng Fan, Kaidi Liu, Yangyang Li, Xiang-Kui Gu, Mingyue Ding
The direct synthesis of dimethyl carbonate (DMC) from CO2 has both theoretical and practical value in carbon neutrality, but its efficiency is far from the application requirements due to the lacks of understanding of reaction mechanism and rational design of catalyst. Herein, abundant electron-enriched lattice oxygen species were introduced into CeO2 catalyst by constructing a large number of point
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Self-Assembly Morphology Manipulation by Side-chain Engineering of Quinoxaline-Substituted Organic Photothermal Molecules for Efficient Solar-Thermal Conversion and Application Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Jing Li, Luoqing Wang, Yuyu Pan, Han Wang, Chenyang Zhang, Shizhang Li, Xian-Kai Chen, Tao Jia, Kai Wang
Organic photothermal materials have attracted more and more attention due to the structural diversity, flexibility, and compatibility. However, the energy conversion efficiency is limited due to the narrow absorption spectrum, strong reflection/transmittance and insufficient non-radiative decay. Herein, we synthesized two quinoxaline-based D-A-D-A-D type molecules with ethyl (BQE) or carboxylate (BQC)
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Near-Infrared Light Activated Formulation for the Spatially Controlled Release of CRISPR-Cas9 Ribonucleoprotein for Brain Gene Editing Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Susana Simões, Miguel Lino, Angela Barrera, Catarina Rebelo, Francesca Tomatis, Andreia Vilaça, Christopher Breunig, Andrea Neuner, João Peça, Ricardo González, Alexandra Carvalho, Stefan Stricker, Lino Ferreira
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Classifieds: Jobs and Awards, Products and Services Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18
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High-throughput DNA synthesis for data storage Chem. Soc. Rev. (IF 46.2) Pub Date : 2024-03-18 Meng Yu, Xiaohui Tang, Zhenhua Li, Weidong Wang, Shaopeng Wang, Min Li, Qiuliyang Yu, Sijia Xie, Xiaolei Zuo, Chang Chen
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SO2 capture and detection with carbon microfibers (CMFs) synthesised from polyacrylonitrile Chem. Commun. (IF 4.9) Pub Date : 2024-03-18 Ana Yañez-Aulestia, Valeria B. López-Cervantes, Juan Marcos Esparza Shulz, Diego Solis-Ibarra, Ilich A. Ibarra, Salomón Cordero-Sánchez, Elí Sánchez-González, Reyna Ojeda-López
SO2 emissions not only affect local air quality but can also contribute to other environmental issues. Developing low-cost and robust adsorbents with high uptake and selectivity is needed to reduce SO2 emissions. Here, we show the SO2 adsorption-desorption capacity of carbon microfibers (CMFs) at 298 K. CMFs showed a reversible SO2 uptake capacity (5 mmol g-1), cyclability over ten adsorption cycles
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Synthesis and immunological evaluation of TLR1/2 ligand-conjugated RBDs as self-adjuvanting vaccine candidates against SARS-CoV-2 Chem. Commun. (IF 4.9) Pub Date : 2024-03-15 Yoshiyuki Manabe, Brandon Gárate-Reyes, Keita Ito, Ramón Hurtado-Guerrero, Kazuya Kabayama, Koichi Fukase
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Materials in Radiative Cooling Technologies Adv. Mater. (IF 29.4) Pub Date : 2024-03-18 Rong Liu, Shancheng Wang, Zhengui Zhou, Keyi Zhang, Guanya Wang, Changyuan Chen, Yi Long
Radiative cooling (RC) is a carbon-neutral cooling technology that utilizes thermal radiation to dissipate heat from the Earth's surface to the cold outer space. Research in the field of RC has garnered increasing interest from both academia and industry due to its potential to drive sustainable economic and environmental benefits to human society by reducing energy consumption and greenhouse gas emissions
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Polyelectrolyte Hydrogel-Functionalized Photothermal Sponge Enables Simultaneously Continuous Solar Desalination and Electricity Generation without Salt Accumulation Adv. Mater. (IF 29.4) Pub Date : 2024-03-18 Lin Li, Chaorui Xue, Qing Chang, Xiaohu Ren, Ning Li, Jinlong Yang, Shengliang Hu, Haolan Xu
Technologies that can simultaneously generate electricity and desalinate seawater are highly attractive and required to meet the increasing global demand for power and clean water. Here we develop a bifunctional solar evaporator that features continuous electric generation in seawater without salt accumulation by rational design of polyelectrolyte hydrogel-functionalized photothermal sponge. This evaporator
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Achieving Zero-Temperature Coefficient Point Behavior by Defect Passivation for Temperature-Immune Organic Field-Effect Transistors Adv. Mater. (IF 29.4) Pub Date : 2024-03-18 Jiannan Qi, Kai Tie, Yue Ma, Yinan Huang, Wenbing Gong, Shougang Sun, Zhongwu Wang, Zhiyun Li, Rong Huang, Jinshun Bi, Liqiang Li, Xiaosong Chen, Wenping Hu
Organic field-effect transistors (OFETs) have broad prospects in biomedical, sensor, and aerospace applications. However, obtaining temperature-immune OFETs is difficult because the electrical properties of organic semiconductors (OSCs) are temperature-sensitive. The zero-temperature coefficient (ZTC) point behavior can be used to achieve a temperature-immune output current; however, it is difficult
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An Electro-optical Kerr Device Based on 2D Boron Nitride Liquid Crystals for Solar-blind Communications Adv. Mater. (IF 29.4) Pub Date : 2024-03-18 Youan Xu, Ziyang Huang, Zehao Zhang, Baofu Ding, Peixuan Li, Jiarong Liu, Yugan Hao, Lixin Dai, Hao Zhang, Caizhen Zhu, Wei Cai, Bilu Liu
Achieving light modulation in the spectral range of 200 – 280 nm is a prerequisite for solar-blind ultraviolet communication, where current technologies mainly based on the electro-luminescent self-modulation of the ultraviolet source. External light modulation through the electro-birefringence control of liquid crystal devices has shown success in the visible-to-infrared regions. However, the poor
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Freestanding Serpentine Silicon Strips with Ultrahigh Stretchability over 300% for Wearable Electronics Adv. Mater. (IF 29.4) Pub Date : 2024-03-15 Yihao Shi, Jianzhong Zhao, Bingchang Zhang, Jiahao Qin, Xinyue Hu, Yuan Cheng, Jia Yu, Jiansheng Jie, Xiaohong Zhang
Well-functionalized electronic materials, such as silicon, in a stretchable format are desirable for high-performance wearable electronics. However, obtaining Si materials that meet the required stretchability of over 100% for wearable applications remains a significant challenge. Herein, a rational design strategy is proposed to achieve freestanding serpentine Si strips (FS-Si strips) with ultrahigh
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Tailoring Perovskite Surface Potential and Chelation Advances Efficient Solar Cells Adv. Mater. (IF 29.4) Pub Date : 2024-03-13 Wenlong Shao, Haibing Wang, Shiqiang Fu, Yansong Ge, Hongling Guan, Chen Wang, Cheng Wang, Ti Wang, Weijun Ke, Guojia Fang
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Sequentially Processed Bulk-Heterojunction-Buried Structure for Efficient Organic Solar Cells with 500 nm Thickness Adv. Mater. (IF 29.4) Pub Date : 2024-03-13 Huarui Zhang, Yuqiang Liu, Guangliu Ran, Hongxiang Li, Wenkai Zhang, Pei Cheng, Zhishan Bo
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A Two-Decade Journey of Continuous Innovation at the National Center for Nanoscience and Technology of China (NCNST) Adv. Mater. (IF 29.4) Pub Date : 2024-03-17 Qing Dai, Zhixiang Wei, Zhiyong Tang, Yuliang Zhao
This special issue of Advanced Materials celebrates the 20th anniversary of the National Center for Nanoscience and Technology of China (NCNST), showcasing a diverse array of cutting-edge research in nanoscience and nanotechnology. This issue highlights recent advances in nanomaterials for devices, nanomedicine, energy, and catalysis applications. NCNST is a pioneering institution established on December
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Living Synthelectronics: A New Era for Bioelectronics Powered by Synthetic Biology Adv. Mater. (IF 29.4) Pub Date : 2024-03-17 Jing Sun, Ruofan Yang, Qingsong Li, Runtao Zhu, Ying Jiang, Lei Zang, Zhibo Zhang, Wei Tong, Hang Zhao, Tengfei Li, Hanfei Li, Dianpeng Qi, Guanglin Li, Xiaodong Chen, Zhuojun Dai, Zhiyuan Liu
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Nanodiamond-Enhanced Magnetic Resonance Imaging (Adv. Mater. 11/2024) Adv. Mater. (IF 29.4) Pub Date : 2024-03-14 Jelena Lazovic, Eberhard Goering, Anna-Maria Wild, Peter Schützendübe, Anitha Shiva, Jessica Löffler, Gordon Winter, Metin Sitti
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Split-Type Magnetic Soft Tactile Sensor with 3D Force Decoupling (Adv. Mater. 11/2024) Adv. Mater. (IF 29.4) Pub Date : 2024-03-14 Huangzhe Dai, Chengqian Zhang, Chengfeng Pan, Hao Hu, Kaipeng Ji, Haonan Sun, Chenxin Lyu, Daofan Tang, Tiefeng Li, Jianzhong Fu, Peng Zhao
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The Stability of Hydrogen-Bonded Ion-Pair Complex Unexpectedly Increases with Increasing Solvent Polarity Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Debashree Manna, Rabindranath Lo, Jaroslav Vacek, Vijay Madhav Miriyala, Petr Bouř, Tao Wu, Zuzana Osifova, Dana Nachtigallová, Martin Dračinský, Pavel Hobza
The generally observed decrease of the electrostatic energy in the complex with increasing solvent polarity has led to the assumption that the stability of the complexes with ion-pair hydrogen bonds decreases with increasing solvent polarity. Besides, the smaller solvent-accessible surface area (SASA) of the complex in comparison with the isolated subsystems results in a smaller solvation energy of
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The Celiac-Disease Superantigen Oligomerizes and Increases Permeability in an Enterocyte Cell Model Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Maria Georgina Herrera, Maria Julia Amundarain, Philipp W Dörfler, Veronica I Dodero
Celiac disease (CeD) is an autoimmune disorder triggered by gluten proteins, affecting approximately 1% of the global population. The 33-mer deamidated gliadin peptide (DGP) is a metabolically modified wheat-gluten superantigen for CeD. Here, we demonstrate that the 33-mer DGP spontaneously assembles into oligomers with a diameter of approximately 24 nm. The 33-mer DGP oligomers present two main secondary
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Radicalizing CO by Mononuclear Palladium(I) Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Tim Bruckhoff, Joachim Ballmann, Lutz H. Gade
A mononuclear, T-shaped palladium(I) d9 metalloradical (3), stabilized by a bulky carbazole-based PNP-ligand, was obtained by reduction of palladium chloride or thermal Pd-C bond homolysis of the corresponding neopentyl complex. Pressurizing with CO gave the Pd(I) carbonyl complex, which was structurally characterized by X-ray diffraction. Delocalization of the unpaired electron to the carbonyl carbon
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Dual Enhancement of Phosphorescence and Circularly Polarized Luminescence through Entropically Driven Self-Assembly of a Platinum(II) Complex Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Yanqing Wang, Na Li, Liangwen Chu, Zelin Hao, Junyu Chen, Jiang Huang, Junlin Yan, Hongtao Bian, Pengfei Duan, Jing Liu, Yu Fang
Addressing the dual enhancement of circular polarization (glum) and luminescence quantum yield (QY) in circularly polarized luminescence (CPL) systems poses a significant challenge. In this study, we present an innovative strategy utilizing the entropically driven self-assembly of amphiphilic phosphorescent platinum(II) complexes (L-Pt) with tetraethylene glycol chains, resulting in unique temperature
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Light-Regulated Nucleation for Growing Highly Uniform Single-Crystalline Microrods Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Lishan Sun, Yanjun Gong, Yanxue Che, Hongwei Ji, Bing Liu, Yanke Che, Jincai Zhao
We report a light-irradiation method to control the synchronous nucleation of a donor-acceptor (D-A) fluorophore for growing highly uniform single-crystalline microrods, which is in sharp contrast to the prevailing methods of inhibiting spontaneous nucleation and additionally adding seeds. The D-A fluorophore was observed to undergo photoinduced electron transfer to CrCl3, leading to the generation
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Experimental Evidence for Non-Fermi-Contact J Coupling Across Chalcogen Bonds in Ionic Salt Cocrystal Polymorphs Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Tamali Nag, Victor V. Terskikh, David L. Bryce
A pair of novel polymorphic ionic cocrystals of 3,4-dicyanotelluradiazole and tetraphenylphosphonium bromide are synthesized and are characterized by single-crystal XRD. Strong and directional non-covalent chalcogen bonds (ChB) between Te and Br are analyzed via solid-state NMR to reveal large and anisotropic J(125Te,79/81Br) coupling tensors, providing unequivocal evidence for non-Fermi contact contributions
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Stereodivergent, Kinetically Controlled Isomerization of Terminal Alkenes via Nickel Catalysis Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Camille Z. Rubel, Anne K. Ravn, Hang Chi Ho, Shenghua Yang, Zi-Qi Li, Keary Mark Engle, Julien C. Vantourout
Because internal alkenes are more challenging synthetic targets than terminal alkenes, metal-catalyzed olefin mono-transposition (i.e., positional isomerization) approaches have emerged to afford valuable E- or Z- internal alkenes from their complementary terminal alkene feedstocks. However, the applicability of these methods has been hampered by lack of generality, commercial availability of precatalysts
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Introducing Carborane Clusters into Crystalline Frameworks via Thiol-yne Click Chemistry for Energetic Materials Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Tian-Li Pu, Xu-Yang Wang, Zhi-Bing Sun, Xi-Yan Dong, Qian-You Wang, Shuang-Quan Zang
Crystalline frameworks represent a cutting-edge frontier in material science, and recently, there has been a surge of interest in energetic crystalline frameworks. However, the well-established porosity often leads to diminished output energy, necessitating a novel approach for performance enhancement. Thiol-yne coupling, a versatile metal-free click reaction, has been underutilized in crystalline
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Metabolic Glycoengineering-Enabled Molecularly Specific Acoustic Tweezing Cytometry for Targeted Mechanical Stimulation of Cell Surface Sialoglycans Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Weiping Li, Jiatong Guo, Eric C. Hobson, Xufeng Xue, Qingjiang Li, Jianping Fu, Cheri X. Deng, Zhongwu Guo
This study developed a new type of dibenzocyclooctyne (DBCO)-functionalized microbubbles (MBs) and validated their attachment to azide-labelled sialoglycans on human pluripotent stem cells (hPSCs) generated via metabolic glycoengineering (MGE). This enabled application of mechanical forces to sialoglycans on hPSCs via molecularly specific acoustic tweezing cytometry (mATC), i.e., displacing sialoglycan-anchored
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Reduction-Tolerance Electrolyte Design for High-Energy Lithium Batteries Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Chuangchao Sun, Ruhong Li, Suting Weng, Chunnan Zhu, Long Chen, Sen Jiang, Long Li, Xuezhang Xiao, Chengwu Liu, Lixin Chen, Tao Deng, Xuefeng Wang, Xiulin Fan
Lithium batteries employing Li or silicon (Si) anodes hold promise for the next-generation energy storage systems. However, their cycling behavior encounters rapid capacity degradation due to the vulnerability of solid electrolyte interphases (SEIs). Though anion-derived SEIs mitigate this degradation, the unavoidable reduction of solvents introduces heterogeneity to SEIs, leading to fractures during
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Photocatalytic Functionalization of Dehydroalanine-Derived Peptides in Batch and Flow Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Nikolaos Kaplaneris, Merve Akdeniz, Méritxell Fillols, Francesca Arrighi, Fabian Raymenants, Gana Sanil, Daniel T. Gryko, Timothy Noel
Unnatural amino acids, and their synthesis via the late-stage functionalization (LSF) of peptides, play a crucial role in areas such as drug design and discovery. Historically, the LSF of biomolecules has predominantly utilized traditional synthetic methodologies that exploit nucleophilic residues, such as cysteine, lysine or tyrosine. In this study, we present a photocatalytic hydroarylation process
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Iso-E-Codelock: A Rebuilding-free Electrochemical Chip with a Customizable Decoding Probe for Real-Time and Portable Pathogen Diagnostics Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-18 Yichen Liu, Yidan Tang, Yin Bao, Kaiwei Cai, Baiyang Lu, Rujian Zhao, Chunxu Yu, Yan Du, Bingling Li
In order to realize portable pathogen diagnostics with easier quantitation, digitization and integration, we develop a ready-to-use electrochemical sensing strategy (Iso-E-Codelock) for real-time detection of isothermal nucleic acid amplification. Bridged by a branch DNA as codelock, the isothermal amplicon is transduced into increased current of an electrochemical probe, holding multiple advantages
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Robust Covalent Organic Framework Photocatalysts for H2O2 Production: Linkage Position Matters Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Tao Yang, De Zhang, Aiguo Kong, Yingying Zou, Ling Yuan, Chao Liu, Sijia Luo, Guangfeng Wei, Chengzhong Yu
Covalent organic frameworks (COFs) are promising photocatalysts for hydrogen peroxide (H2O2) synthesis. However, the nature of organic polymers makes the balance between high activity and stability challenging. We demonstrate that the linkage position matters in the design of robust COF photocatalysts with durable high activity without sacrificial reagents. COFs with ortho- and para-linkages (o-COFs
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Enhanced Detection of Novel Low-Frequency Gene Fusions via High-Yield Ligation and Multiplexed Enrichment Sequencing Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Yi Wu, Jinxiao Guo, Wenjun Li, Xuehao Xiu, Deepak Thirunavukarasu, Yudong Wang, Kai Wang, Weiyu Chen, David yu Zhang, Xiurong Yang, Chunhai Fan, Ping Song
Panel-based methods are commonly employed for the analysis of novel gene fusions in precision diagnostics and new drug development in cancer. However, these methods are constrained by limitations in ligation yield and the enrichment of novel gene fusions with low variant allele frequencies. In this study, we conducted a pioneering investigation into the stability of double-stranded adapter DNA, resulting
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The Influence of Ions on the Electrochemical Stability of Aqueous Electrolytes Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Yiming Sui, Alexis Scida, Bo Li, Cheng Chen, Yanke Fu, Yanzhao Fang, Peter Alex Greaney, Tomas Osborn Popp, De-en Jiang, Chong Fang, Xiulei Ji
The electrochemical stability window of water is known to vary with the type and concentration of dissolved salts. However, the underlying influence of ions on the thermodynamic stability of aqueous solutions has not been fully understood. Here, we investigated the electrolytic behaviors of aqueous electrolytes as a function of different ions. Our findings indicate that ions with high ionic potential
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Entropy-Driven Direct Air Electrofixation Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Yuntong Sun, Ming Li, Jingjing Duan, Markus Antonietti, Sheng Chen
According to the rule of chemical thermodynamics, the catalytic activation of small molecules (like N2 in air and CO2 in flue gas) generally exhibits a negative activity dependence on O2 owning to the competitive oxygen reduction reaction (ORR). Nevertheless, some catalysts can show positive activity dependence for N2 electrofixation, an important route to produce ammonia under ambient condition. Here
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The Impact of Metagenomics on Biocatalysis Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Bethany N Hogg, Christian Schnepel, James D Finnigan, Simon J Charnock, Martin A Hayes, Nicholas John Turner
In the ever-growing demand for sustainable ways to produce high-value small molecules, biocatalysis has come to the forefront of greener routes to these chemicals. As such, the need to constantly find and optimise suitable biocatalysts for specific transformations has never been greater. Metagenome mining has been shown to rapidly expand the toolkit of promiscuous enzymes needed for new transformations
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Highly selective acetylene-to-ethylene electroreduction over Cd-decorated Cu catalyst with efficiently inhibited carbon-carbon coupling Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Zeping Wang, Chengyu Li, Gongao Peng, Run Shi, Lu Shang, Tierui Zhang
Electrochemical acetylene reduction (EAR) employing Cu catalysts represents an environmentally friendly and cost-effective method for ethylene production and purification. However, Cu-based catalysts encounter product selectivity issues stemming from carbon-carbon coupling and other side reactions. We explored the use of secondary metals to modify Cu-based catalysts and identified Cd decoration as
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Reticular Modulation of Piezofluorochromic Behaviors in Organic Molecular Cages by Replacing Non-Luminous Components Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Yang Li, Kai Wang, Rui Feng, Jingtian Wang, Xiao-Juan Xi, Feifan Lang, Quanwen Li, Wei Li, Bo Zou, Jiandong Pang, Xian-He Bu
Organic piezochromic materials that manifest pressure-stimuli-responses are important in various fields such as data storage and anticounterfeiting. The manipulation of piezofluorochromic behaviors for these materials is promising but remains a great challenge. Herein, a non-luminous components regulated strategy is developed and organic molecular cages (OMCs), a burgeoning class of crystalline organic
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Enantioselective Hydrofunctionalization of Cyclobutenones: Total Synthesis of gem-Dimethylcyclobutane Natural Products Angew. Chem. Int. Ed. (IF 16.6) Pub Date : 2024-03-17 Shaowei Wang, Changxu Zhong, Yingchao Huang, Ping Lu
Cyclobutanes with a gem-dimethyl group are common motifs in natural products. However, strategies for constructing enantioenriched gem-dimethyl cyclobutanes are still underdeveloped. Herein, we report an enantioselective approach to synthesize a broad group of chiral 2,3-disubstituted cyclobutanones through sequential 1,4-conjugate addition/trapping/cross-coupling of readily available cyclobutenones
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Field-Induced Antiferroelectric–Ferroelectric Transformation in Organometallic Perovskite Displaying Giant Negative Electrocaloric Effect J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Shiguo Han, Jie Bie, Wei Fa, Shuang Chen, Liwei Tang, Wuqian Guo, Haojie Xu, Yu Ma, Yi Liu, Xitao Liu, Zhihua Sun, Junhua Luo
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Engineering the Coordination Environment of Ir Single Atoms with Surface Titanium Oxide Amorphization for Superior Chlorine Evolution Reaction J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Jiaxian Wang, Long Zhao, Yunjie Zou, Jie Dai, Qian Zheng, Xingyue Zou, Lufa Hu, Wei Hou, Ruizhao Wang, Kaiyuan Wang, Yanbiao Shi, Guangming Zhan, Yancai Yao, Lizhi Zhang
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Pyrogenic Carbon Degradation by Galvanic Coupling with Sprayed Seawater Microdroplets J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Ruolan Zhang, Zhenyuan Zhang, Xuke Chen, Jichun Jiang, Lei Hua, Xiuquan Jia, Rui Bao, Feng Wang
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Enantioselective Divergent Syntheses of Diterpenoid Pyrones J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-18 Yunpeng Ji, Yaqian Liu, Weiqiang Guan, Chuning Guo, Hongli Jia, Benke Hong, Houhua Li
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Unprotected Organic Cations─The Dilemma of Highly Li-Concentrated Ionic Liquid Electrolytes J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-17 Shaoning Zhang, Shengan Wu, Jinkwang Hwang, Kazuhiko Matsumoto, Rika Hagiwara
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A Biomimetic Synthetic Strategy Can Provide Keratan Sulfate I and II Oligosaccharides with Diverse Fucosylation and Sulfation Patterns J. Am. Chem. Soc. (IF 15.0) Pub Date : 2024-03-17 Yunfei Wu, Gerlof P. Bosman, Digantkumar Chapla, Chin Huang, Kelley W. Moremen, Robert P. de Vries, Geert-Jan Boons
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Cage escape governs photoredox reaction rates and quantum yields Nat. Chem. (IF 21.8) Pub Date : 2024-03-18 Cui Wang, Han Li, Tobias H. Bürgin, Oliver S. Wenger
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High-throughput and proteome-wide discovery of endogenous biomolecular condensates Nat. Chem. (IF 21.8) Pub Date : 2024-03-18 Pengjie Li, Peng Chen, Fukang Qi, Jinyun Shi, Wenjie Zhu, Jiashuo Li, Peng Zhang, Han Xie, Lina Li, Mengcheng Lei, Xueqing Ren, Wenhui Wang, Liang Zhang, Xufu Xiang, Yiwei Zhang, Zhaolong Gao, Xiaojun Feng, Wei Du, Xin Liu, Limin Xia, Bi-Feng Liu, Yiwei Li
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Molecular vessels from preorganised natural building blocks Chem. Soc. Rev. (IF 46.2) Pub Date : 2024-03-18 Arturo Llamosí, Marek P. Szymański, Agnieszka Szumna