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Recent advances of upconversion nanoparticles-based lateral flow assays for point-of-care testing Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-14 Wanghong He, Meng Wang, Peilin Cheng, Yi Liu, Minli You
Lateral flow assays (LFA), as the most commonly used commercialized point-of-care testing (POCT), has been limited by the detection accuracy for decades. To address this challenge, the improvement of detection sensitivity and quantitative ability become necessary. Therefore, increasing new fluorescent LFA have been developed and attracted lots of attentions. Wherein, the upconversion nanoparticles
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Colorimetric biosensing assays based on gold nanoparticles functionalized/combined with non-antibody recognition elements Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-13 Hu Chen, Songtao Cai, Jianxin Luo, Xiaohu Liu, Lijuan Ou, Qingwen Zhang, Bo Liedberg, Yi Wang
Biosensing assays involving antibody-antigen interactions have been widely applied in diagnostics and healthcare in virtue of their superior selectivity and sensitivity. However, antibodies typically suffer from complex and fragile functional structures, tedious preparation (resource-intensive and time-consuming), and large molecular size. As a result, the application of antibody-based biosensors tends
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Analytical methodology for unveiling human exposure to (micro)plastic additives Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-12 Andrea Estévez-Danta, Juan F. Ayala-Cabrera, Javier López-Vázquez, Mikel Musatadi, Rosa Montes, Nestor Etxebarria, José Benito Quintana, Maitane Olivares, Ailette Prieto, Rosario Rodil, Manuel Miró, Olatz Zuloaga
This review describes a wide variety of analytical approaches for the assessment of human exposure to organic chemicals associated with plastic additives, focusing on works published in the last decade on plasticisers, bisphenols, flame retardants and antioxidants. Physiologically based extraction tests serve as preliminary in-vitro assays to determine the bioaccessibility of these compounds from micro/nanoplastics
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Polymeric porous membranes as solid support and protective material in microextraction processes: A review Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-12 Lutfi Andre Yahya, Marek Tobiszewski, Paweł Kubica, Stanisława Koronkiewicz, Christina Vakh
Polymeric porous membranes have proven to be a versatile and efficient material for microextraction processes. In analytical practice, they are used both as a solid support and as a protective medium for improved sample preparation in various analytical applications. Polymeric porous membranes offer unique advantages in microextraction due to their large surface area and controllable pore size, eliminating
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Untargeted chromatographic methods coupled with chemometric strategies for the analysis of food and related samples Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-11 Federico N. Castañeda, Rocío B. Pellegrino Vidal, Juan Aspromonte
Due to the increasing interest in understanding the complexity of food chemistry and the change in the quality control paradigm for food products, not only a limited number of analytes are considered for analysis, and a more holistic approach is now required for assessing quality in a larger sense. Certainly, the improvement of chromatographic techniques, such as the hyphenation to high resolution
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Recent advances towards the use of deep eutectic solvents and cyclodextrins in the extraction of food contaminants: From traditional sample pretreatment techniques to green microextraction and beyond Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-11 Natasa P. Kalogiouri, Christina Papatheocharidou, Victoria F. Samanidou
There is an emerging need for the development of advanced analytical methods to guarantee food quality and safety. The development of green extraction techniques that employ green solvents for the extraction of contaminants has revolutionized the field of analytical sample preparation. Analytical scientists have turned to the application of alternative extraction techniques of food contaminants which
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Reactive oxygen species-induced microplastics aging: Implications for environmental fate and ecological impact Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-10 Shaochong Liu, Lianzhen Li, Sizhi Liu, Lu Liu, Xiangyang Xiao, Dongemi Zhou, Changyin Zhu, Xilin She
Microplastics (MPs) undergo aging when exposed to reactive oxygen species (ROS), modifying their physical properties, bioavailability, and toxicity, ultimately influencing their environmental fate and transport. Understanding ROS-induced MPs aging is crucial for predicting long-term environmental consequences and developing effective mitigation strategies. This review presents a thorough overview of
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Advances and challenges in portable optical biosensors for onsite detection and point-of-care diagnostics Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-08 Sufian Rasheed, Tehreem Kanwal, Naseer Ahmad, Batool Fatima, Muhammad Najam-ul-Haq, Dilshad Hussain
Portable optical biosensors have emerged as revolutionary tools in point-of-care diagnostics, bringing the healthcare sector to the next level. Developing cutting-edge portable optical sensors represents significant advances in disease detection and monitoring. This review includes classifying optical sensors based on their transduction mechanism, addressing challenges such as sensitivity, specificity
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Human exposure to PAHs through silicone-based passive samplers: Methodological aspects and main findings Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-06 María Murcia-Morales, Francisco José Díaz-Galiano, María José Gómez-Ramos, Amadeo R. Fernández-Alba
Silicone-based passive samplers have emerged as powerful tools for assessing dermal and inhalation exposure to polycyclic aromatic hydrocarbons (PAHs) across diverse environmental settings. Despite their increasing application, the nascent stage of this methodology and the absence of standardized protocols have led to varied monitoring approaches, resulting in fragmented and incomparable datasets.
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The role of chemometrics in improving clinical data analysis and diagnostics Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-06 I. Stanimirova, M. Daszykowski, P.K. Hopke
In recent years, due to the significant development of instrumental techniques, clinical research has acquired many interesting tools and analytical platforms that can support the development of advanced diagnostic methods. Nevertheless, along with these attractive instrument possibilities and the pressure to implement the complementary descriptions of biological systems, there is a need for rational
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Microplastic residues in clinical samples: A retrospection on sources, entry routes, detection methods and human toxicity Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-06 Neha Sharma, Vinay Kumar, Vimal S., Mridul Umesh, Pritha Chakraborty, Thazeem Basheer, Suma Sarojini, Preeti Sharma, Ritu Pasrija, Damia Barcelo
Microplastics (MPs) are emerging toxicants which have been detected in varying environments. Despite MPs adverse effects, reports on MPs detection from human clinical samples are only a few. This is due to several reasons such as inefficiency of current MPs detection techniques to detect them from human clinical samples, lack of understanding about the MPs toxicity to human organs and ethical regulations
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A review of sequential extraction methods for fractionation analysis of toxic metals in solid environmental matrices Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-05 Jamshed Ali, Mustafa Tuzen, Qurat-ul-ain Shaikh, Wahid Bux Jatoi, Xinbin Feng, Guangyi Sun, Tawfik A. Saleh
This review provides a thorough examination of SEMs for the fractionation analysis of toxic metals within solid environmental matrices. It offers an overview of these techniques' principles and applications for determining the chemical fractions of toxic metals associated with such matrices. The review assesses and contrasts the strengths and weaknesses of SEMs for chemical fractionation analysis.
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Phage display based biosensing: Recent advances and challenges Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-05 Mingyang Wang, Shuang Pang, Haohan Zhang, Zhonghuang Yang, Aihua Liu
Phage display enables to screen probes such as peptide, antibody and nanobody with high specificity and affinity to the target, providing excellent probes for various analytical or biosensing platforms. Furthermore, by employing techniques like as genetic engineering and chemical modification, it is possible to conveniently functionalize these ligands for analytical chemistry with selectivity and sensitivity
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Perspectives on sustainable plastic treatment: A shift from linear to circular economy Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-05 Xingdong Shi, Zhijie Chen, Wei Wei, Bing-Jie Ni
The pervasive presence of plastics in the environment, particularly microplastics, has become a significant global challenge, demanding innovative solutions for their management and upcycling. While traditional methods including landfill and incineration face limitations in environmental impact, emerging technologies offer promising pathways for the conversion of plastics into valuable chemicals and
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Optical biosensors utilising viral receptors ACE2 and ACE2 mimics Trends Anal. Chem. (IF 13.1) Pub Date : 2024-03-04 Sian Yang Ow, Laura Sutarlie, Samuel Wei Yang Lim, Nur Asinah Binte Mohamed Salleh, Yuki Tanaka, Chee Kiang Ivan Tan, Xiaodi Su
Common viral infections start from binding of the viral pathogens to the viral receptors on the host body, for example, SARS-CoV-2 infects cells by binding to human angiotensin converting enzyme 2 (ACE2). This review discusses optical biosensors that exploit ACE2 or ACE2 derived peptides (ACE2 mimics) as affinity ligands for detecting SARS-CoV-2. In these biosensors, the target analytes can include
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Critical analysis of green extraction techniques used for botanicals: Trends, priorities, and optimization strategies-A review Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-29 Ciro Cannavacciuolo, Stefania Pagliari, Rita Celano, Luca Campone, Luca Rastrelli
Botanicals are widely used and marketed as food supplements or cosmetics with particular benefits for human health. Botanicals are products manufactured using natural components derived from plants, algae, fungi or lichens. Given the easy accessibility of such products, it is essential to ensure their safety by guaranteeing the absence of chemical or microbiological contamination. Furthermore, since
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Programmable DNA hydrogels construction with functional regulations for biosensing applications Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-29 Chengyu Yan, Yulin Hua, Jiarong Guo, Peng Miao
DNA hydrogels are hydrophilic polymer networks formed by DNA cross-linked polymer backbones or self-assembly of DNA building blocks. Following Watson-Crick base pairing principle and switchable recognition capability towards a wide range of biomolecules, programmable DNA assembly or disassociation events can be applied for the fabrication of highly sensitive biosensors. DNA hydrogels have excellent
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Mass spectrometry for biomarkers, disease mechanisms, and drug development in cerebrospinal fluid metabolomics Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-29 Dongyuan Xu, Xuan Dai, Le Zhang, Yuankun Cai, Keyu Chen, Ji Wu, Lixin Dong, Lei Shen, Jingyi Yang, Jingwei Zhao, Yixuan Zhou, Zhimin Mei, Wei Wei, Zhaowei Zhang, Nanxiang Xiong
The high incidence rate, complexity, and intractability of central nervous system (CNS) diseases drive significant interest in understanding the underlying mechanisms involved in the immune response. Cerebrospinal fluid (CSF) is the key biological fluid for the study of CNS diseases. Mass spectrometry (MS)-based metabolomics investigations benefit from the advantages of high sensitivity, high selectivity
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Empowerment of AI algorithms in biochemical sensors Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-29 Zhongzeng Zhou, Tailin Xu, Xueji Zhang
Biochemical sensors have become indispensable tools for real-time, on-site monitoring and analysis in diverse domains such as healthcare, environmental protection, and food safety. The rapid evolution of artificial intelligence (AI) has opened new frontiers for enhancing the capabilities of these sensors across a spectrum of detection modalities. This paper delves into the recent integration of AI
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Pressurized liquid extraction of organic contaminants in environmental and food samples Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-28 Yolanda Soriano, Vicente Andreu, Yolanda Picó
Pressurized liquid extraction (PLE) is an automated technique for extracting compounds, including organic contaminants (OCs) that are strongly bind to the matrix. This technique offers various advantages provides advantages such as reduced extraction time, decreased solvent and energy consumption, simultaneous multiple extractions, and concurrent clean-up capability. This review presents an updated
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Insights into sensing applications of fluorescent covalent organic frameworks Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-27 Chengtao Gong, Chunxing Yan, Jialiang Liu, Jiahao Li, Jiangen Fu, Chunhong Chen, Ying Huang, Guozan Yuan, Yongwu Peng
Covalent organic frameworks (COFs), as meticulously designed porous crystalline materials, have garnered significant interdisciplinary attention. Notably, extensive efforts have been directed towards creating fluorescent COFs by strategically integrating fluorophores, optimized conjugated structures, and exploring diverse topologies, utilizing luminescent mechanisms like aggregation-induced emission
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A critical review of chromatographic methods for analyzing haloacetic acids in water: Advances, uncertainties, and prospects Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-26 Wei Ma, Wenyu Li, Baiyang Chen, Yang Yang, Jie Yang
Haloacetic acids (HAAs), which are the second largest group of halogenated disinfection byproducts, raise great analytical challenges because of their hydrophilicity, non-volatility, and acidity. To determine HAAs in drinking water, many pretreatment methods (such as extraction and derivatization) have been proposed since 2000. These methods vary significantly in principles and performance, each carrying
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Advancements in biosensing of hormones: Recent progress and future trends Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-23 Milad Baghal Behyar, Arezoo Mirzaie, Mohammad Hasanzadeh, Nasrin Shadjou
Hormones play a crucial role as signaling molecules, produced by different glands in the body and transported through the bloodstream to target organs, tissues, and cells. Disorders in hormonal processes can lead to various diseases. Due to the significant impact of hormones on human health, precise and rapid monitoring is essential. This study delves into the use of new nanomaterials in the development
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Analytical micro and nano technologies meet sepsis diagnosis Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-23 José M. Gordón Pidal, Águeda Molinero-Fernández, María Moreno-Guzmán, Miguel Ángel López, Alberto Escarpa
Sepsis is one of the deadliest health disorders in the current century due to specific limitations in early and differential diagnosis. Therefore, early diagnosis and appropriate treatment of sepsis are crucial research areas to prevent human death worldwide. Among other clinical manifestations, protein biomarker detection has shown outstanding characteristics to provide relevant biological information
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Recent advances in metal-organic framework-based nanozymes and their enabled optical biosensors for food safety analysis Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-23 Huirong Hou, Li Wang, Yibo Gao, Jianfeng Ping, Fengnian Zhao
As a convenient and efficient analytical tool, the optical biosensor plays an essential part in the on-site and rapid detection for food safety. To expand its practical application, enzyme-mimicking nanomaterials (nanozymes), in particular metal-organic framework (MOF)-based nanozymes have been fabricated and applied in optical biosensors due to their abundant catalytic sites and stable catalytic activities
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Pressurized liquid extraction for the determination of bioactive compounds in plants with emphasis on phenolics Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Ana Miklavčič Višnjevec, Laura Barp, Paulo Lucci, Sabrina Moret
Pressurized liquid extraction (PLE) is considered an advanced extraction technique because it can save time and reduce solvent consumption compared to traditional extraction methods. It is a solid-liquid extraction performed at high temperatures and high pressure. Considering the importance of enhancing the value of by-products or waste products and the increased use of high-temperature extraction
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Advances in the analysis of disinfection by-products with mass spectrometry: Sample preparation and target/non-target screening Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Jianfa Gao, Foon Yin Lai, Cristina Postigo, Mengting Yang
The identification and quantification of disinfection by-products (DBPs) in disinfected water is challenging due to their high chemodiversity and low concentration levels. There is a clear trend in developing new methods and improving the related methodology for qualitative and quantitative analysis of DBPs in different water matrices, such as drinking water and reclaimed water. This article reviews
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Magnetic multifunctional nanomaterials for enhanced transverse chemical and bioanalytical applications – A review Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Farooq Sher, Emina Boškailo, Narcisa Smječanin, Monica R. Nemțanu, Emina K. Sher, Eder C. Lima
The present study focused on the ability to combine magnetic NMs to enable the use of their synergistic additives and new properties for the development of different sensing systems in various fields. A novel kind of integration of magnetic NPs in the sensing systems results in its significant improvement of sensitivity, limit of detection and stability. The applicability of NPs as colourimetric sensors
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Stimuli-responsive 19F MRI probes: From materials design to in vitro detection and in vivo diagnosis Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Xianglong Zhu, Pengbo Zhang, Dong Liu, Ling Tao, Jinge Du, Xia Gao
Accurate detection and diagnosis allow healthcare professionals to precisely identify patient's disease and enable the clinicians to implementation the most appropriate and effective treatment. While conventional H magnetic resonance imaging (MRI) has underscored vital utility in anatomical imaging and pathological examination, F MRI distinguishes itself for its heightened sensitivity, minimal background
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MOF-functionalized paper-based biosensors: Fabrications, mechanisms and applications Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Jiaqi Huang, Jiajun Pan, Yiteng Song, Qian Lin, Yuzhi Xu, Zong Dai, Si-Yang Liu
Point-of-care testing (POCT) biosensors are rapidly developing in recent years because of the urgent needs for rapid test and home test. Among various types of POCT biosensors, paper-based biosensors have occupied large market share owing to the advantages of cost-effectiveness, portability and simplicity. To further meet the increasing requirement of POCT in various application scenes, the functionalization
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Exploration and application of chemico-biology detection methods and patterns for factors inducing protein misfolding Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-22 Xiaochen Gao, Jia Zhai, Xuan He, Wenjing Ding, Baoxing Shen
Protein misfolding and aggregation are the leading cause of many diseases, including neuron degenerative diseases, cardiovascular diseases, and cancers. However, the inducing factors and mechanisms behind protein misfolding remain largely unrevealed, due to the lack of efficient analyzing and probing methods for the detection of inducing substrates and protein labelling. In this review, we investigated
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Quantification and mapping of RNA modifications Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-21 Jun Xiong, Jianyuan Wu, Yu Liu, Ya-Jing Feng, Bi-Feng Yuan
In addition to the four canonical nucleobases, RNA molecules undergo various chemical modifications. To date, more than 170 structurally diverse RNA modifications have been discovered across all three domains of life. These RNA modifications play crucial roles in a wide range of biological processes, such as regulating gene expression, maintaining RNA stability, and facilitating protein translation
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Applications of environmental mass spectrometry in atmospheric haze chemistry Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-21 Tianzeng Chen, Yanli Ge, Biwu Chu, Peng Zhang, Qingxin Ma, Hong He
The diverse components, sources, and concentration levels of pollutants in the atmosphere pose significant challenges to understanding the complex formation processes of atmospheric haze. With the advent of environmental mass spectrometry, researchers have been able to gain deeper insights into the composition and further expound the formation mechanisms of atmospheric haze. This review provides a
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Current trends in the sorbent-based extraction of illegal drugs from biofluids: Solid sorbents and configurations Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 P. García-Atienza, H. Martínez-Pérez-Cejuela, J.M. Herrero-Martínez, S. Armenta
Analysis of illegal drugs in biofluids typically requires the incorporation of an adequate sample treatment step together with high performance instrumentation to meet the high demands of the modern Analytical Chemistry in terms of sensitivity and selectivity. Regarding the main objective, sample treatment can be addressed to: i) the extraction of a large number of different compounds; or ii) the selective
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Current trends in the determination of organic compounds in foodstuffs using matrix solid phase dispersion Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 L, ., , R, a, m, o, s
Since its introduction in 1989 by Barker and co-workers, the acceptation of matrix solid-phase dispersion (MSPD) has increased steadily and it is now considered a well-stablished technique in many application fields. In these three decades, MSPD has evolved from being a technique mainly used for the disruption and simultaneous extraction of biological tissues, to gain increasing acceptation in other
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Deep learning in spectral analysis: Modeling and imaging Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Xuyang Liu, Hongle An, Wensheng Cai, Xueguang Shao
Deep learning (DL) is powerful to find patterns or hidden information from data using neural networks. With the growth of data and computing capabilities, DL has rapidly advanced and shown great power in scientific research. In recent years, DL methods have been widely explored in spectral analysis. This review provides an overview of the advancements in DL techniques and highlights their recent applications
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MOFs/COFs-based hybrids for agricultural sensors: Current state of art and beyond Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Xin Liu, Peidi Fan, Xiaoyu Su, Lei Cai, Cui Wu, Yong Qiu, Weijie Yu, Feng Xu, Jianfeng Ping, Ping Wang, Hao Wan, Yuxiang Pan
Reticular chemistry enables the precise prediction for metal-organic frameworks (MOFs) and covalent organic frameworks (COFs) by opening up an infinite space of the chemical compositions, structures, and material properties. Leveraging the reticular design, MOFs and COFs (MOFs/COFs)-based hybrids have made significant advances in both fundamental properties and sensor applications. MOFs/COFs-based
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Advancements and emerging technologies in biosensors for rapid and accurate virus detection Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Giovanna Marrazza, Murugan Ramalingam, Abinaya Jaisankar, Lijia Cheng, Giulia Selvolini, Ilaria Antonia Vitale
Infectious diseases originating from viruses are emerging as a major global health concern. The recent epidemic events related to various respiratory viruses, including coronavirus 2, have been reported worldwide and raised much concern. Starting from this point, early detection of infectious diseases plays a crucial role in both preventing their spread and helping the therapeutic treatment of affected
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Deciphering the research of Micro(nano)plastics: An in-depth bibliometric expedition into ecotoxicological impacts and research trends Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Wanjing Liu, Min Zeng, Ye Li, Guanglong Chen, Jing Wen, Jun Wang
Micro(nano)plastics pollution has become a significant and unavoidable issue, and research on the toxicity of micro(nano)plastics is experiencing an explosive trend. We comprehensively retrieved all articles (total 2506) on the toxicity of micro(nano)plastics in the Web of Science Core Collection from the initiation of the concept of micro(nano)plastics to the present. Through bibliometric analysis
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Noninvasive strategies of cell-tracking in vivo Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Yuxiang Han, Yimin Li, Wei Emma Wu, Zhibo Liu
In recent years, cell-based therapy, such as adoptive immunotherapy and stem cell restorative therapy, was followed with interest. However, restricted understanding of the metabolic and functional characteristics of the adoptive cells in vivo hinders the clinical translation of these therapeutic cells. For example, the distribution, proliferation, and homing of CAR-T cells in vivo are not clear, so
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2D nanomaterials as electrochemical (bio)sensing transducers in the post-graphene era Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Alexandros Ch Lazanas, Mamas I. Prodromidis
This review centers upon two-dimensional (2D) nanomaterials beyond graphene and their utilization in the development of novel electrochemical (bio)sensors and analytical devices. The text is organized in three main sections including the presentation of the most important families of 2D nanomaterials, an outline of “top-down” and hydro(solvo)thermal methods which are commonly employed for the production
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NMR spectroscopic applications to atmospheric organic aerosol analysis – Part 2: A review of existing methodologies and perspectives Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Emilio Tagliavini, Stefano Decesari, Marco Paglione, Andrea Mazzanti
In the last decade, the considerable technological progress achieved in parallel science disciplines provides a potential for a breakthrough in NMR atmospheric applications. Improvements in probe sensitivity and in the NMR devices, like innovative tubes with a better filling factor, enable to improve the signal-to-noise ratios of an order of magnitude with respect to the earlier techniques. This already
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Microplastic occurrences, transport, and quantification and associated effects on primary productivity and carbon cycling processes in freshwater ecosystems Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-20 Fan Wu, Xianrui Ha, Shuoyue Wang, Jiajia Li, Yang Gao
Microplastic (MP) research has mostly focused on individual organisms while few focus on the functional processes participated by multiple organisms. Thus, a comprehensive introduction of biogeochemical carbon (C) transfer via food chain is still missing from the available knowledgebase. Accordingly, this study analyzes potential MP sources and distribution, abundance, and transport patterns in freshwater
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Covalent organic frameworks nanocomposites and their role in performance enhancement of bioanalysis based biosensor Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-16 Jundong Wang, Jingming Zhong, Wen Luo, Qiang Han, Mingyu Ding
As a kind of crystalline organic porous material, covalent organic frameworks (COFs) have been employed in bioanalysis owing to its outstanding intrinsic properties including stable structure, optional building block, highly tunable porosity, large specific surface area, π-π stacking interactions, unique photoelectric property and ordered channel. Multiplex and multidimensional bioanalysis represents
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Trends in sample preparation and analysis of current use pesticides in abiotic environmental matrices Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-16 Jiehong Guo, An Li
Current-use pesticides (CUPs) are the replacements of legacy organochlorine pesticides. The increasing use of CUPs has resulted in their occurrence in various environmental matrices including water, air, soil and sediment. The diversity in the physicochemical properties of CUPs and the complexity of the matrices pose challenges in the selection and optimization of laboratory methods for their measurement
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Green metrics for analytical methodologies: Uncovering sustainable chromatography approaches for detecting emerging contaminants in food and environmental water Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-16 Nor Munira Hashim, Maisarah Nasution Waras, Noorfatimah Yahaya, Muggundha Raoov, Abuzar Kabir, Nur Nadhirah Mohamad Zain
The ecological impact of chemical and analytical studies involving toxic reagents and solvents remains a concern. Hence, analytical-based greenness assessments are necessary to estimate emerging contaminants (ECs) with minimal environmental hazards. Greenness evaluation is essential for determining the viability of adopting sustainable practices. This review presented a comprehensive outlook of chromatography
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Artificial intelligence and water quality: From drinking water to wastewater Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-15 C.H. Pérez-Beltrán, A.D. Robles, N.A. Rodriguez, F. Ortega-Gavilán, A.M. Jiménez-Carvelo
The transformative impact of Artificial Intelligence (AI) technologies, particularly Machine Learning (ML), on the analysis of spectroscopic data in water quality assessment cannot be overstated. We remark the ways in which AI and ML have revolutionized the analysis and prediction of water quality parameters. These technologies efficiently process spectral data from various sources, identify contaminants
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Corrigendum to “Recent advances in illicit drug detection sensor technology in water” [TrAC Trends in Anal. Chem. 168 (2023) 117295] Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-15 Keugtae Kim, Stephanie Stoll, Rajendra Singh, Woo Hyoung Lee, Jae-Hoon Hwang
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Green analytical chemistry metrics for evaluation of microextraction methods: Fascinating or essential tools in real-world applications? Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-11 Noorfatimah Yahaya, Ahmad Husaini Mohamed, Mazidatulakmam Miskam, Aemi Syazwani Abdul Keyon, Saw Hong Loh, Nur Nadhirah Mohamad Zain, Muhammad Sajid
The twelve principles of Green Analytical Chemistry serve as a guideline for introducing greenness in the analytical methods. Microextraction-based sample preparation has been developed as a greener alternative to large-scale liquid-liquid extraction and solid-phase extraction, minimizing the amount of solvents, eliminating toxic substances, reducing sample size, and generating less waste. However
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Novel sorptive extraction techniques in bioanalysis evaluated by Blue Applicability Grade Index: The paradigm of fabric phase sorptive extraction and capsule phase microextraction Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-10 Natalia Manousi, Justyna Płotka-Wasylka, Victoria Samanidou
Fabric phase sorptive extraction (FPSE) and capsule phase microextraction (CPME) are two sol-gel derived microextraction techniques that emerged in the last decade towards the minimization of the environmental impact of conventional sample preparation approaches. Complementary to the well-established green metric tools, Blue Applicability Grade Index (BAGI) was recently proposed for the evaluation
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Fluorescent nanomaterials for the detection of chronic kidney disease Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-09 Poornima Bhatt, Deepak Kukkar, Ki-Hyun Kim
The preliminary identification of chronic kidney disease (CKD) is crucial because of its high-risk factors for complications. Currently, diverse forms of chronic kidney disease biomarkers (CKDBs) (e.g., serum creatinine [CR], kidney injury molecule-1, neutrophil gelatinase-associated lipocalin, and cystatin C [cys C]) are available for the medical assessment of kidney diseases. The fluorescent (FL)
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Nanozyme-enhanced paper-based biosensor technologies Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-09 Anupriya Baranwal, Ravi Shukla, Vipul Bansal
Nanozymes, enzyme-mimetic nanomaterials that combine features of nanoscale material with the catalytic properties of enzymes, have undergone rapid development in recent years. While enzymes have remained integral to biosensor technologies for the past several decades, the emerging potential of nanozymes to overcome the low stability and high production costs of biological enzymes has turned them into
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Multiplexed electrochemical sensing devices for chronic diseases diagnosis and monitoring Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-08 Maria-Bianca Irimes, Alexandra Pusta, Andreea Cernat, Bogdan Feier, Mihaela Tertis, Cecilia Cristea, Anca Dana Buzoianu, Radu Oprean
Chronic diseases are persistent health conditions that affect a large number of patients worldwide and have serious implications on the health status of patients, representing a global challenge from both a medical and an economic point of view. Thus, rapid and accurate diagnosis, as well as disease monitoring, represent key steps in the optimal management in clinical practice. In an attempt to achieve
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Applications of metal organic frameworks in point of care testing Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-08 Fotouh R. Mansour, Sherin F. Hammad, Inas A. Abdallah, Alaa Bedair, Reda M. Abdelhameed, Marcello Locatelli
Diagnostic devices used in the point-of-care (POC) today play a critical role as tools to provide essential medical surveillance data and to ensure that patients receive appropriate and timely care. These devices also allow self-analysis by the patient, increasing therapeutic adherence as well as reducing pressure on clinical structures. The development of new diagnostic tools, therefore, represents
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Challenges and perspectives of CRISPR-based technology for diagnostic applications Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-08 Stefano Del Giovane, Neda Bagheri, Andrea Celeste Di Pede, Alejandro Chamorro, Simona Ranallo, Davide Migliorelli, Loïc Burr, Samantha Paoletti, Hatice Altug, Alessandro Porchetta
The precision and versatility of CRISPR-based techniques, combined with the advantages of nucleic acid-based nanotechnology, hold great promise in transforming the landscape of molecular diagnostics. While significant progress has been made, current CRISPR-based platforms primarly focus on nucleic acid detection. To expand the applicability and fully leverage the advantages offered by CRISPR-based
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Playing with biological selectivity: Antimicrobial peptides and bacteriophages-based optical biosensors for pathogenic bacteria detection Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-08 Carmen Cuntín-Abal, Beatriz Jurado-Sánchez, Alberto Escarpa
Bacteria monitoring is of paramount significance for healthcare systems worldwide and to assess food or water quality monitoring. In this review, advances during the last 10 years in optical biosensors based on antimicrobial peptides and bacteriophages for bacteria detection are described. Such probes possess high stability which allows for chemical and other modification for highly directed selectivity
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Lung disease characterised via synchrotron radiation micro-CT and digital volume correlation (DVC) Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-07 Hari Arora, Dale Kernot, Louis Giron, David Howells, Michael Darcy, Makoto Hoshino, Kentaro Uesugi, Raoul van Loon, Gaku Tanaka, Toshihiro Sera
The study of lung mechanics is important to futureproof resilience against potential novel threats to lung health. Medical imaging provides insight to lung function. High-resolution, high-speed synchrotron radiation micro-CT imaging at SPring-8 (Japan) and mechanics were used to characterize healthy and diseased airways. Synchrotron radiation was important to maximize speed and spatial resolution to
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Recent progress and applications of Raman spectrum denoising algorithms in chemical and biological analyses: A review Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-07 Shiyan Fang, Siyi Wu, Zhou Chen, Chang He, Linley Li Lin, Jian Ye
Raman spectroscopy is a powerful technique widely used in analytical chemistry. However, spectral noise emerging during detection introduces potential to compromise the signal-to-noise ratio, undermining the accuracy and reliability of sample analyses. This limitation has driven the development of Raman spectrum denoising algorithms to encourage the application of Raman spectroscopy in more complicated
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Covalent organic frameworks for detection of ions Trends Anal. Chem. (IF 13.1) Pub Date : 2024-02-06 Meng Wang, Yutian Qin, Zhixi Li, Zhe Song, Yue Wan, Jing Du, Meina Song, Shaopeng Li, Shun Zhang, Meiting Zhao
Covalent organic frameworks (COFs) are a class of ordered organic network materials with permanent pore structures. The physical and chemical properties of COFs such as porosity, fluorescence, and acid-base stability can be tuned through the topological, linkage, and building block regulation. These features make COFs promising candidates in various applications and especially for detection originating