Frequency dependent multiphase flows on centrifugal microfluidics.,Lab on a Chip

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Frequency dependent multiphase flows on centrifugal microfluidics.
Lab on a Chip ( IF 6.1 ) Pub Date : 2020-01-03 , DOI: 10.1039/c9lc00924h
Esmail Pishbin ₁ , Amin Kazemzadeh ₂ , Mohammadreza Chimerad ₁ , Sasan Asiaei ₁ , Mahdi Navidbakhsh ₁ , Aman Russom ₂

Affiliation

The simultaneous flow of gas and liquids in large scale conduits is an established approach to enhance the performance of different working systems under critical conditions. On the microscale, the use of gas-liquid flows is challenging due to the dominance of surface tension forces. Here, we present a technique to generate common gas-liquid flows on a centrifugal microfluidic platform. It consists of a spiral microchannel and specific micro features that allow for temporal and local control of stratified and slug flow regimes. We investigate several critical parameters that induce different gas-liquid flows and cause the transition between stratified and slug flows. We have analytically derived formulations that are compared with our experimental results to deliver a general guideline for designing specific gas-liquid flows. As an application of the gas-liquid flows in enhancing microfluidic systems' performance, we show the acceleration of the cell growth of E. coli bacteria in comparison to traditional culturing methods.

中文翻译：

频率相关的多相流在离心微流体系统上。

大型管道中气体和液体的同时流动是一种在临界条件下增强不同工作系统性能的既定方法。在微观尺度上，由于表面张力的优势，气液流的使用具有挑战性。在这里，我们提出了一种在离心微流控平台上产生常见气液流的技术。它由螺旋形微通道和特定的微特征组成，可对分层和团状流态进行时间和局部控制。我们研究了几个关键参数，这些参数会引起不同的气液流量并导致分层流和段塞流之间的过渡。我们将分析得出的配方与我们的实验结果进行比较，以提供设计特定气液流量的一般指南。

更新日期：2020-02-13

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