The phytochemistry of Hypericum perforatum (St. John’s wort) has been elaborated extensively owing to its immense application in medicinal chemistry. Illustrated pharmacological activities like antidepressant, antiviral, and antibacterial effects demonstrated its substantiation for numerous of the conventional purposes reported for St John’s wort. St. John’s wort is herbal remedy extensively used in mild to moderate depression. Most of pharmacological activities were assigned to presence of photosensitive naphthodianthrone; hypericin and other allied flavonoid constituents. Escalating demands of hyperforin as antidepressant added more lure to H. perforatum L. The crude extracts of H. perforatum containing phloroglucinols were used for free radical scavenging and against DNA damage. To meet increasing demands of this drug, researchers need to tailor out the biosynthetic pathways to improve secondary metabolite. This necessitated advancement in biotechnological intervention to improve phytochemical potential of this growing herb. This review will brief out ecology, chemistry and phytochemical efficacy with respective phytoconstituents. Further, review will emphasize biotechnological interventions including both conventional and modern contrivances that have been implemented to augment the glory of this species.

中文翻译：

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贯叶连翘的偷窥：植物化学，植物化学功效和生物技术干预

由于贯叶连翘（St. John's wort）的植物化学在药物化学中的广泛应用，因此对其进行了详尽的阐述。举例说明的药理活性，如抗抑郁，抗病毒和抗菌作用证明了其对圣约翰草报道的许多常规目的的证实。圣约翰草是广泛用于轻度至中度抑郁症的草药。大部分药理活性归因于光敏萘二蒽酮的存在。金丝桃素和其他相关的类黄酮成分。升级的hyperforin的需求作为抗抑郁剂增加了更多的引诱到贯叶连翘L.的粗提物贯叶连翘含有间苯三酚的物质可用于清除自由基和抵抗DNA损伤。为了满足对该药物不断增长的需求，研究人员需要调整生物合成途径以改善次生代谢产物。这就需要在生物技术干预方面取得进展，以提高这种正在生长的草药的植物化学潜力。这篇综述将简要介绍各自植物成分的生态，化学和植物化学功效。此外，审查将着重于生物技术干预措施，包括传统的和现代的改进措施，这些措施已被实施以增强该物种的荣耀。