In order to analyze the effect of vascular wall structures on static and dynamic mechanical properties of vascular grafts, small calibre PHBHHx (Poly(3-hydroxybutyrate-co-3-hydroxhexanoate)) vascular grafts (inner diameter 6 mm) with various wall shapes and thicknesses were fabricated by changing electrospinning time and receiving molds. As spinning time increased, wall thickness of the vascular grafts increased and both circumferential tensile strength and suture retention strength improved significantly. When the wall thicknesses of straight grafts were about 120 μm, the great radial dynamic compliance was exhibited, however, the tensile strength and suture retention strength of the straight tubes can’t reach the requirements of normal blood vessel grafting. With the wall thicknesses increasing above 250 μm, although the circumferential tensile strength and suture retention strength gradually achieved the transplanting requirements, the dynamic compliance of the straight tubes declined too sharply to adapt the blood radial shock. For corrugated grafts, the effect of wall thickness on radial dynamic compliance was little, and the radial dynamic compliance was close to that of the commercial vascular grafts. The circumferential tensile strength and suture retention strength of the corrugated grafts were also improved to approach the commercial vessels’ performances with the wall thickness improving to about 425 μm. Elastic recovery rates of all the prepared vascular grafts were superior to that of the commercial sample. Along with the wall thickness exceeding 250 μm, the water permeabilities of both the straight and the corrugated grafts were less than 300 ml/(cm²·min).

为了分析血管壁结构对血管移植物静态和动态力学性能的影响，使用了小口径PHBHHx（内径6 mm的聚（3-羟基丁酸酯-co-3-羟基己酸酯））血管移植物，其壁面形状和形状各不相同。通过改变静电纺丝时间和接收模具来制造厚度。随着纺丝时间的增加，血管移植物的壁厚增加，周向拉伸强度和缝合线保持强度均显着提高。当直管移植物的壁厚约为120μm时，会表现出很大的径向动态顺应性，但是直管的抗张强度和缝合线保持强度无法达到正常血管移植的要求。随着壁厚增加到250μm以上，尽管周向抗张强度和缝线保持强度逐渐达到了移植要求，但直管的动态顺应性却急剧下降，无法适应血液径向冲击。对于波纹状移植物，壁厚对径向动态顺应性的影响很小，并且径向动态顺应性接近商业血管移植物。波纹状移植物的周向抗张强度和缝合线保持强度也得到了改善，以接近商用船的性能，壁厚提高到了约425μm。所有制备的血管移植物的弹性恢复率均优于商业样品。随着壁厚超过250μm，²分钟）。