Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus.,The Journal of Antibiotics

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Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus.
The Journal of Antibiotics ( IF 2.1 ) Pub Date : 2019-12-06 , DOI: 10.1038/s41429-019-0263-z
E-Eum Woo ₁ , Lee Su Ha ₁ , Ji-Yul Kim ₁ , In-Kyoung Lee ₁ , Bong-Sik Yun ₁

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Two new sesquiterpenes (1 and 2) together with one known compound (3) were isolated from the culture broth of Coprinus rhizophorus. Chemical structures of these compounds were deduced by spectroscopic methods. Compound 1 exhibited free-radical-scavenging activity against the 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical. Compounds 2 and 3 exhibited antimicrobial activities against Saccharomyces cerevisiae, Propionibacterium acnes, and Staphylococcus epidermidis.

中文翻译：

根瘤菌A和B，根瘤菌培养液中的新倍半萜。

从根腐鬼伞的培养液中分离出两个新的倍半萜烯（1和2）以及一种已知的化合物（3）。这些化合物的化学结构通过光谱法推导。化合物1对2，2′-叠氮基双-（3-乙基苯并噻唑啉-6-磺酸）（ABTS）自由基具有自由基清除活性。化合物2和3对啤酒酵母，痤疮丙酸杆菌和表皮葡萄球菌具有抗菌活性。

更新日期：2019-12-06

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