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Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus

The Journal of Antibiotics volume 73, pages 175–178 (2020)Cite this article

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Abstract

Two new sesquiterpenes (1 and 2) together with one known compound (3) were isolated from the culture broth of Coprinus rhizophorus. Chemical structures of these compounds were deduced by spectroscopic methods. Compound 1 exhibited free-radical-scavenging activity against the 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical. Compounds 2 and 3 exhibited antimicrobial activities against Saccharomyces cerevisiae, Propionibacterium acnes, and Staphylococcus epidermidis.

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Fig. 1
Fig. 2

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Acknowledgements

This study was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future Planning (NRF-2016R1A2B2014430). Authors thank Ms Ji-Young Oh, Center for University Research Facility (CURF) at Jeonbuk National University, for NMR measurement.

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  1. Division of Biotechnology and Advanced Institute of Environment and Bioscience, College of Environmental and Bioresource Sciences, Jeonbuk National University, Iksan-si, Korea

    E-Eum Woo, Lee Su Ha, Ji-Yul Kim, In-Kyoung Lee & Bong-Sik Yun

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  1. E-Eum Woo
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Correspondence to Bong-Sik Yun.

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Woo, EE., Ha, L.S., Kim, JY. et al. Rhizophins A and B, new sesquiterpenes from the culture broth of Coprinus rhizophorus. J Antibiot 73, 175–178 (2020). https://doi.org/10.1038/s41429-019-0263-z

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