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Characterizing the BCR repertoire in immune-mediated diseases.
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2020-01-01 , DOI: 10.1038/s41584-019-0339-y
Nitya S Ramadoss 1, 2 , William H Robinson 1, 2
Affiliation  

B cells can assume protective or pathogenic roles in immune-mediated diseases (IMDs). Analysis of the B cell receptor (BCR) repertoires in six IMDs provides insights into the diversity of B cell repertoires across diseases as well as into potential pathological mechanisms and the effects of different treatments.

中文翻译:

表征免疫介导疾病中的 BCR 库。

B 细胞可以在免疫介导疾病 (IMD) 中发挥保护或致病作用。对六种 IMD 中的 B 细胞受体 (BCR) 库的分析提供了对跨疾病 B 细胞库的多样性以及潜在病理机制和不同治疗效果的见解。
更新日期:2019-11-29
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