It is poorly understood how group 3 innate lymphoid cells (ILC3s) recognize metabolites produced by the gut microbiota. In this issue of Immunity, Chun et al. show that short-chain fatty acids sensed through the G protein-coupled receptor Ffar2 promote ILC3 function in the colon.

中文翻译：

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结肠ILC3对代谢产物的感应：Ffar2距离太远了吗？

人们对第3组先天淋巴样细胞（ILC3）如何识别肠道菌群产生的代谢物了解甚少。在本期《免疫》中，Chun等人。结果表明，通过G蛋白偶联受体Ffar2感知的短链脂肪酸可促进结肠中ILC3的功能。