A glycoprotein inhibiting the growth of colon cancer cells was isolated from sheep intestinal mucous membrane. The glycoprotein, designated IGP, was purified by a combination of ion-exchange chromatography over DEAE-650M and gel-filtration over HW-55F. Purified IGP had a molecular mass of ~60 kDa and consisted of 68.72 ± 2.10% protein and 32.09 ± 1.52% carbohydrates. The monosaccharide composition of the carbohydrate part consisted of glucose (31.28% of the total carbohydrate content), glucosamine (22.28%) and N-acetylgalactosamine (19.38%), mannose (11.14%), fucose (11.28%), and rhamnose (4.64%). The amino-acid composition of IGP was also determined.

从绵羊肠粘膜中分离出一种抑制结肠癌细胞生长的糖蛋白。该糖蛋白被命名为IGP，通过DEAE-650M上的离子交换层析和HW-55F上的凝胶过滤相结合来纯化。纯化的 IGP 的分子量约为 60 kDa，由 68.72 ± 2.10% 蛋白质和 32.09 ± 1.52% 碳水化合物组成。碳水化合物部分的单糖组成为葡萄糖（占碳水化合物总含量的31.28%）、葡萄糖胺（22.28%）和N-乙酰半乳糖胺（19.38%）、甘露糖（11.14%）、岩藻糖（11.28%）和鼠李糖（4.64%）。 %）。还测定了 IGP 的氨基酸组成。