Aminophthalide derivatives of cytisine, anabasine, and salsoline were obtained in high yields via condensation of the alkaloids with o-formylbenzoic acid. Their structures were proven using ¹H and ¹³C NMR spectroscopy and data from 2D COSY ¹H–¹H and HMQC ¹H–¹³C spectra. Studies of their antimicrobial activity showed moderate antimicrobial activity of 3-(N-cytisin-1-yl)isobenzofuran-1(3H)-one and 3-(N-salsolin-1-yl)isobenzofuran-1(3H)-one against Gram-positive test strain Staphylococcus aureus ATCC 6538 and Gram-negative test strain Escherichia coli ATCC 25922.

中文翻译：

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金雀花碱、新木木碱和猪毛菜碱的苯并呋喃衍生物的合成及抗菌活性

通过生物碱与邻甲酰基苯甲酸的缩合，高产率地获得了金雀花碱、新木香和猪油碱的氨基苯酞衍生物。^使用1 H 和¹³ C NMR 光谱以及 2D COSY ¹ H– ¹ H 和 HMQC ¹ H– ¹³ C 光谱数据证明了它们的结构。其抗菌活性研究表明，3-( N-金雀花素-1-基)异苯并呋喃-1(3H ) -一和3-( N -salsolin-1-基)异苯并呋喃-1(3H ) -具有中等抗菌活性一种针对革兰氏阳性测试菌株金黄色葡萄球菌ATCC 6538 和革兰氏阴性测试菌株大肠杆菌ATCC 25922。