In cancer, alternative polyadenylation has been shown to lead to altered 3′ UTRs with different regulatory potentials. A study now suggests a mechanism that leads to 3′ UTR lengthening and translational repression of a subset of metastasis-suppressing genes, revealing a new prospective therapeutic vulnerability.

中文翻译：

---

剪裁 3' UTR 改变转移潜能

在癌症中，替代性聚腺苷酸化已被证明会导致具有不同调节潜力的 3' UTR 改变。现在的一项研究提出了一种导致 3' UTR 延长和转移抑制基因子集翻译抑制的机制，揭示了一种新的前瞻性治疗脆弱性。