A shared fate for nuclear and cytosolic inclusions,Nature Cell Biology

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A shared fate for nuclear and cytosolic inclusions
Nature Cell Biology ( IF 17.3 ) Pub Date : 2023-04-20 , DOI: 10.1038/s41556-023-01121-z
Simon Alberti ₁ , Serena Carra _{1,

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Affiliation

Coordination of protein quality control processes across organelles is poorly understood. A study now shows that the cytosolic juxtanuclear quality control (JUNQ) and intranuclear quality control (INQ) compartments face each other on opposite sides of the nuclear envelope before their vacuolar degradation, promoting proteostasis.

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