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Interventions for ADHD in childhood and adolescence: A systematic umbrella review and meta-meta-analysis
Clinical Psychology Review ( IF 13.7 ) Pub Date : 2023-03-25 , DOI: 10.1016/j.cpr.2023.102271
Selina Türk 1 , Ann-Kathrin Korfmacher 1 , Heike Gerger 2 , Saskia van der Oord 3 , Hanna Christiansen 1
Affiliation  

There are several meta-analyses of treatment effects for children and adolescents with attention deficit hyperactivity disorder (ADHD). The conclusions of these meta-analyses vary considerably. Our aim was to synthesize the latest evidence of the effectiveness of psychological, pharmacological treatment options and their combination in a systematic overview and meta-meta-analyses. A systematic literature search until July 2022 to identify meta-analyses investigating effects of treatments for children and adolescents with ADHD and ADHD symptom severity as primary outcome (parent and teacher rated) yielded 16 meta-analyses for quantitative analyses. Meta-meta-analyses of pre-post data showed significant effects for pharmacological treatment options for parent (SMD = 0.67, 95% CI 0.60 to 0.74) and teacher ADHD symptom ratings (SMD = 0.68, 95% CI 0.54 to 0.82) as well as for psychological interventions for parent (SMD = 0.42, 95% CI 0.33 to 0.51) and teacher rated symptoms (SMD = 0.25, 95% CI 0.12 to 0.38). We were unable to calculate effect sizes for combined treatments due to the lack of meta-analyses. Our analyses revealed that there is a lack of research on combined treatments and for therapy options for adolescents. Finally, future research efforts should adhere to scientific standards as this allows comparison of effects across meta-analyses.



中文翻译:

儿童和青少年时期多动症的干预措施:系统性总体回顾和荟萃分析

对于患有注意力缺陷多动障碍 (ADHD) 的儿童和青少年的治疗效果有多项荟萃分析。这些荟萃分析的结论差异很大。我们的目的是通过系统概述和荟萃分析来综合心理、药物治疗方案及其组合有效性的最新证据。截至 2022 年 7 月,系统性文献检索旨在确定以 ADHD 儿童和青少年治疗效果以及 ADHD 症状严重程度为主要结果(家长和教师评分)的荟萃分析,得出 16 项荟萃分析用于定量分析。前后数据的荟萃分析显示,药物治疗选择对父母(SMD = 0.67,95% CI 0.60 至 0.74)和教师 ADHD 症状评分(SMD = 0.68,95% CI 0.54 至 0.82)也有显着影响。至于对家长(SMD = 0.42,95% CI 0.33至0.51)和教师评定症状(SMD = 0.25,95% CI 0.12至0.38)的心理干预。由于缺乏荟萃分析,我们无法计算联合治疗的效果大小。我们的分析表明,缺乏针对青少年的联合治疗和治疗选择的研究。最后,未来的研究工作应遵循科学标准,因为这样可以比较荟萃分析的效果。

更新日期:2023-03-25
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