Nuclear condensates in YAP1-driven ependymoma,Nature Cell Biology

当前位置： X-MOL 学术 › Nat. Cell Biol. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Nuclear condensates in YAP1-driven ependymoma
Nature Cell Biology ( IF 17.3 ) Pub Date : 2023-02-02 , DOI: 10.1038/s41556-022-01081-w
Mahsa Shahidi Dadras ₁ , Howard A Fine ₁

Affiliation

An ependymoma subtype is driven by fusion proteins related to the transcriptional regulator YAP1. Research now shows that localization of these fusion proteins within nuclear condensates is necessary and sufficient for tumour formation through the activation of various genetic and epigenetic oncogenic mechanisms.

中文翻译：